# HISTORY 05 Oct 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20161005: cellular organisms_PTN000091176 has function DNA binding (GO:0003677) 20161005: cellular organisms_PTN000091176 has function DNA topoisomerase type II (ATP-hydrolyzing) activity (GO:0003918) 20161005: cellular organisms_PTN000091176 has function endodeoxyribonuclease activity, producing 3'-phosphomonoesters (GO:0016889) # cellular_component 20161005: Archaea_PTN000091251 is NOT found in nuclear chromosome (GO:0000228) 20161005: Eukaryota_PTN000091177 is found in nuclear chromosome (GO:0000228) # biological_process 20161005: Archaea_PTN000091251 does NOT participate in reciprocal meiotic recombination (GO:0007131) 20161005: Eukaryota_PTN000091177 participates in reciprocal meiotic recombination (GO:0007131) 20161005: Eukaryota_PTN000091177 participates in meiotic DNA double-strand break formation (GO:0042138) 20161005: Eukaryota_PTN000091177 participates in meiotic DNA double-strand break processing (GO:0000706) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).