# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 18 Nov 2015: redistribution of PTN000364676 from PTHR14127 to PTHR10799 14 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function # cellular_component 20150226: Eukaryota_PTN000364676 is found in cytoplasm (GO:0005737) # biological_process 20150226: Eukaryota_PTN000364676 participates in regulation of apoptotic process (GO:0042981) 20150226: Eukaryota_PTN000364676 participates in negative regulation of mRNA splicing, via spliceosome (GO:0048025) 20150226: Dictyostelium_PTN000858052 does NOT participate in regulation of apoptotic process (GO:0042981) 20150226: Dictyostelium_PTN001332314 does NOT participate in regulation of apoptotic process (GO:0042981) 20150226: Trypanosomatidae_PTN001649723 does NOT participate in regulation of apoptotic process (GO:0042981) 20150226: Dictyostelium_PTN000857916 does NOT participate in regulation of apoptotic process (GO:0042981) 20150226: Viridiplantae_PTN001326485 does NOT participate in regulation of apoptotic process (GO:0042981) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).