# HISTORY 29 Sep 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20160929: Eukaryota_PTN000075631 has function proton-transporting ATPase activity, rotational mechanism (GO:0046961) # cellular_component 20160929: Eumetazoa_PTN000842132 is NOT found in fungal-type vacuole membrane (GO:0000329) 20160929: Monosiga brevicollis_A9V9J6 is NOT found in fungal-type vacuole membrane (GO:0000329) 20160929: Amoebozoa_PTN000075691 is NOT found in fungal-type vacuole membrane (GO:0000329) 20160929: Fungi_PTN000842151 is found in fungal-type vacuole membrane (GO:0000329) 20160929: Eukaryota_PTN000075631 is found in vacuolar proton-transporting V-type ATPase, V1 domain (GO:0000221) 20160929: Opisthokonta_PTN000842131 is found in lysosomal membrane (GO:0005765) # biological_process 20160929: Eukaryota_PTN000075631 participates in vacuolar acidification (GO:0007035) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).