# molecular_function 20160307: Eukaryota_PTN001638807 lost/modified transcription factor activity, RNA polymerase II transcription factor recruiting (GO:0001135) capacity 20160307: Eukaryota_PTN001638807 lost/modified RNA polymerase II transcription factor activity, sequence-specific DNA binding (GO:0000981) capacity 20160307: root_PTN000067606 has function RNA polymerase II transcription factor activity, sequence-specific DNA binding (GO:0000981) 20160307: root_PTN000067606 has function transcription factor activity, RNA polymerase II transcription factor recruiting (GO:0001135) 20160307: root_PTN000067606 has function transcription factor activity, sequence-specific DNA binding (GO:0003700) 20160307: root_PTN000067606 has function sequence-specific DNA binding (GO:0043565) 20160307: root_PTN000067606 has function transcription regulatory region DNA binding (GO:0044212) # cellular_component 20160307: Opisthokonta_PTN001289598 located in snRNA-activating protein complex (GO:0019185) 20160307: Eukaryota_PTN001638961 located in snRNA-activating protein complex (GO:0019185) 20160307: root_PTN000067606 located in nucleus (GO:0005634) # biological_process 20160307: Opisthokonta_PTN000837192 participates in termination of RNA polymerase I transcription (GO:0006363) 20160307: Eukaryota_PTN001638807 lost/modified regulation of transcription from RNA polymerase II promoter (GO:0006357) capacity 20160307: Eukaryota_PTN001638807 participates in transcription initiation from RNA polymerase I promoter (GO:0006361) 20160307: Eukaryota_PTN001638807 participates in termination of RNA polymerase I transcription (GO:0006363) 20160307: Eukaryota_PTN001638820 participates in mitotic spindle assembly (GO:0090307) 20160307: Eukaryota_PTN000743470 participates in snRNA transcription from RNA polymerase II promoter (GO:0042795) 20160307: Eukaryota_PTN001638961 participates in snRNA transcription from RNA polymerase III promoter (GO:0042796) 20160307: Eukaryota_PTN000743470 participates in snRNA transcription from RNA polymerase III promoter (GO:0042796) 20160307: Magnoliophyta_PTN001319540 participates in regulation of stomatal movement (GO:0010119) 20160307: Pentapetalae_PTN001637115 participates in stamen development (GO:0048443) 20160307: Pentapetalae_PTN001637068 participates in negative regulation of transcription, DNA-templated (GO:0045892) 20160307: Magnoliophyta_PTN000067939 participates in positive regulation of transcription, DNA-templated (GO:0045893) 20160307: Eukaryota_PTN000067791 participates in mitotic cell cycle (GO:0000278) 20160307: Eukaryota_PTN000067791 participates in positive regulation of transcription, DNA-templated (GO:0045893) 20160307: root_PTN000067606 participates in cell differentiation (GO:0030154) 20160307: root_PTN000067606 participates in regulation of transcription from RNA polymerase II promoter (GO:0006357) 20160307: Eukaryota_PTN001638961 participates in snRNA transcription from RNA polymerase II promoter (GO:0042795) # Notes Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).