# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.12 # molecular_function 20160119: Euteleostomi_PTN001635232 has function extracellular matrix binding (GO:0050840) # cellular_component 20160119: Euteleostomi_PTN001635232 is found in extracellular space (GO:0005615) # biological_process 20160119: Euteleostomi_PTN001635232 participates in cell adhesion (GO:0007155) 20160119: Euteleostomi_PTN001635232 participates in positive regulation of bone resorption (GO:0045780) 20160119: Euteleostomi_PTN001635232 participates in osteoblast differentiation (GO:0001649) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).