# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.12 # molecular_function 20150213: cellular organisms_PTN000063907 has function translation initiation factor activity (GO:0003743) 20150213: cellular organisms_PTN000063907 has function ribosome binding (GO:0043022) # cellular_component 20150213: cellular organisms_PTN000063907 is found in ribosome (GO:0005840) 20150213: Eukaryota_PTN000063908 is found in eukaryotic translation initiation factor 2B complex (GO:0005851) 20150213: Eukaryota_PTN000063908 is found in eukaryotic 48S preinitiation complex (GO:0033290) 20150213: Eukaryota_PTN000063908 is found in multi-eIF complex (GO:0043614) 20150213: Eukaryota_PTN000063908 is found in eukaryotic translation initiation factor 2 complex (GO:0005850) # biological_process 20150213: cellular organisms_PTN000063907 participates in translational initiation (GO:0006413) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).