# HISTORY
07 May 2016: Updated by: TOUCHUP-v1.18
14 Mar 2016: Updated by: TOUCHUP-v1.12
24 Mar 2016: Updated by: TOUCHUP-v1.15

# molecular_function
20150806: cellular organisms_PTN000058283 contributes to function RNA binding (GO:0003723) 

# cellular_component
20150806: cellular organisms_PTN000058283 is found in intracellular ribonucleoprotein complex (GO:0030529) 
20150806: node_PTN000058284 is found in catalytic step 2 spliceosome (GO:0071013) 
20150806: node_PTN000058284 is found in U2-type prespliceosome (GO:0071004) 
20150806: node_PTN000058284 is found in U12-type spliceosomal complex (GO:0005689) 
20150806: Eukaryota_PTN000058285 is found in U5 snRNP (GO:0005682) 
20150806: Eukaryota_PTN000058285 is found in U1 snRNP (GO:0005685) 
20150806: Eukaryota_PTN000058285 is found in precatalytic spliceosome (GO:0071011) 
20150806: Eukaryota_PTN000058285 is found in P granule (GO:0043186) 
20150806: Eukaryota_PTN000058285 is found in spliceosomal tri-snRNP complex (GO:0097526) 
20150806: Eukaryota_PTN000058285 is found in U2 snRNP (GO:0005686) 
20150806: Eukaryota_PTN000058285 is found in U4 snRNP (GO:0005687) 
20150806: Eukaryota_PTN000058285 is found in SMN-Sm protein complex (GO:0034719) 
20150806: Eukaryota_PTN000058361 is found in U6 snRNP (GO:0005688) 
20150806: Eukaryota_PTN000058361 is found in Lsm1-7-Pat1 complex (GO:1990726) 
20150806: Eukaryota_PTN000058361 is found in spliceosomal tri-snRNP complex (GO:0097526) 

# biological_process
20150806: cellular organisms_PTN000058283 participates in RNA processing (GO:0006396) 
20150806: Eukaryota_PTN000058285 participates in mRNA splicing, via spliceosome (GO:0000398) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
This family contains the Sm protein SMX2 (aka Smg1 or SNRPG) and the corresponding "Like Sm" protein LSM7. The Sm proteins are ancient and highly conserved in eukaryotes and Archaea and are related to the bacterial Hf1 proteins (Mura et al. 2014; PMID:23579284)
The Sm proteins are part of heteroheptameric complex (composed of Smb1, Smd1, Smd2, Smd3, Sme1, Smx3, and Smx2) that are essential components of the spliceosomal U1, U2, U4, and U5 snRNPs.
The Lsm proteins 1-8 are found in two seven membered Lsm rings, each containing Lsm2-7, and containing either Lsm1 or Lsm8. The complex containing Lsm8 localizes to the nucleus where it binds the U6 snRNA and is involved in spliceosomal splicing. The complex containing Lsm1 is cytoplasmic where it associates with he Pat1p decapping enzyme and Xrn1p exoribonucleases and is involved in mRNA degradation.

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).