# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.12 # molecular_function 20150204: node_PTN000048695 has function DNA ligase (ATP) activity (GO:0003910) # cellular_component 20150204: node_PTN000048695 is found in cytoplasm (GO:0005737) 20110128: Eukaryota_PTN000048698 is found in DNA ligase IV complex (GO:0032807) 20150204: Opisthokonta_PTN000825456 is found in DNA-dependent protein kinase-DNA ligase 4 complex (GO:0005958) 20120329: Eukaryota_PTN000048763 is found in mitochondrion (GO:0005739) 20150204: Eukaryota_PTN000048763 is found in nucleus (GO:0005634) # biological_process 20150204: node_PTN000048695 participates in lagging strand elongation (GO:0006273) 20150204: node_PTN000048695 participates in DNA ligation involved in DNA repair (GO:0051103) 20150204: Eukaryota_PTN000048698 participates in nucleotide-excision repair, DNA gap filling (GO:0006297) 20120329: Eukaryota_PTN000048698 participates in double-strand break repair via nonhomologous end joining (GO:0006303) 20150204: Euteleostomi_PTN000048704 participates in immunoglobulin V(D)J recombination (GO:0033152) 20150204: Eukaryota_PTN000048794 participates in Okazaki fragment processing involved in mitotic DNA replication (GO:1903461) 20150204: Eukaryota_PTN000048794 does NOT participate in DNA ligation involved in DNA repair (GO:0051103) 20150204: Eukaryota_PTN000048765 does NOT participate in lagging strand elongation (GO:0006273) 20150204: Eukaryota_PTN000048698 does NOT participate in lagging strand elongation (GO:0006273) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES PG Reannotated family. PG 2015-02-05 # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).