# HISTORY 06 Jun 2016: Saved by pascalegaudet using Paint 2.0-beta19 # molecular_function 20160606: Eukaryota_PTN000044668 has function urate oxidase activity (GO:0004846) 20160606: node_PTN000044713 has function carboxy-lyase activity (GO:0016831) 20160606: Euteleostomi_PTN000044593 has function thyroid hormone binding (GO:0070324) # cellular_component 20160606: Bacteria _PTN001624581 is found in peroxisome (GO:0005777) 20160606: Euteleostomi_PTN000044593 is found in extracellular space (GO:0005615) # biological_process 20160606: Eukaryota_PTN000044668 participates in allantoin biosynthetic process (GO:0019428) 20160606: node_PTN000044586 participates in purine nucleobase metabolic process (GO:0006144) 20160606: Euteleostomi_PTN000044593 does NOT participate in purine nucleobase metabolic process (GO:0006144) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).