# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.12 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20151112: root_PTN000039458 has function beta-glucosidase activity (GO:0008422) 20151112: Chordata_PTN001620447 has function beta-galactosidase activity (GO:0004565) 20151112: Chordata_PTN001620447 has function glycosylceramidase activity (GO:0017042) 20151112: Euteleostomi_PTN000039495 has function fibroblast growth factor receptor binding (GO:0005104) 20151112: Euteleostomi_PTN000039495 has function signal transducer activity (GO:0004871) 20151112: Euteleostomi_PTN000039495 has function fibroblast growth factor binding (GO:0017134) 20151112: Euteleostomi_PTN000039543 has function lactase activity (GO:0000016) 20151112: Amniota_PTN000039520 has LOST/MODIFIED function beta-glucosidase activity (GO:0008422) # cellular_component 20151112: Chordata_PTN001620447 is found in cytosol (GO:0005829) 20151112: Euteleostomi_PTN000039466 is found in endoplasmic reticulum (GO:0005783) 20151112: Euteleostomi_PTN000039495 is found in integral component of plasma membrane (GO:0005887) 20151112: Euteleostomi_PTN000039543 is found in integral component of plasma membrane (GO:0005887) 20151112: node_PTN000039749 is found in cytosol (GO:0005829) # biological_process 20151112: root_PTN000039458 participates in glycosyl compound metabolic process (GO:1901657) 20151112: Chordata_PTN001620447 participates in glycosylceramide catabolic process (GO:0046477) 20151112: Euteleostomi_PTN000039495 participates in fibroblast growth factor receptor signaling pathway (GO:0008543) 20151112: Pentapetalae_PTN001620535 participates in response to hormone (GO:0009725) 20151112: Pentapetalae_PTN001620535 participates in glucosinolate catabolic process (GO:0019762) 20151112: Pentapetalae_PTN001620535 participates in response to salt stress (GO:0009651) 20151112: node_PTN000039749 participates in single-organism carbohydrate catabolic process (GO:0044724) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES MAF: Due to the high level of duplications in plant, I did not propagate plant annotations within highly duplicated families. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).