# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.12 # molecular_function 20141208: Eukaryota_PTN000035478 has function 3'-5'-exodeoxyribonuclease activity (GO:0008296) 20141208: Gammaproteobacteria_PTN000035572 has function 3'-5'-exodeoxyribonuclease activity (GO:0008296) # cellular_component 20110103: node_PTN000035347 is found in nucleus (GO:0005634) 20110103: Eukaryota_PTN000035411 is found in zeta DNA polymerase complex (GO:0016035) 20110103: Eukaryota_PTN000035348 is found in alpha DNA polymerase:primase complex (GO:0005658) 20110103: Eukaryota_PTN000035478 is found in delta DNA polymerase complex (GO:0043625) # biological_process 20141208: Eukaryota_PTN000035411 participates in error-prone translesion synthesis (GO:0042276) 20141208: Eukaryota_PTN000035348 participates in lagging strand elongation (GO:0006273) 20141208: Eukaryota_PTN000035348 participates in leading strand elongation (GO:0006272) 20120330: Eukaryota_PTN000035348 participates in double-strand break repair via nonhomologous end joining (GO:0006303) 20110104: Eukaryota_PTN000035478 participates in DNA replication proofreading (GO:0045004) 20110104: Eukaryota_PTN000035478 participates in base-excision repair, gap-filling (GO:0006287) 20141208: Eukaryota_PTN000035478 participates in nucleotide-excision repair, DNA gap filling (GO:0006297) 20141208: Gammaproteobacteria_PTN000035572 participates in DNA replication proofreading (GO:0045004) 20141208: Gammaproteobacteria_PTN000035572 participates in SOS response (GO:0009432) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES MSL, 4 Jan 2011 First pass curation Revised 26 Aug 2011, MSL: Added answers from wiki PG reannotated 2014-12-08 Disputes SWIS protein P09884 GO:0003896 IDA ECO:0000314 PMID:2175912 (Dispute ID: 1853) POLA1 does not have primase activity; it acts after the primase, to elongate the fragments synthesized by the primase. SourceForge https://sourceforge.net/p/geneontology/ontology-requests/11389/ # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).