# HISTORY 13 Aug 2016: Saved by suzi using Paint 2.22 14 Mar 2016: Updated by: TOUCHUP-v1.12 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150724: root_PTN000817051 has function ubiquitin protein ligase activity (GO:0061630) # cellular_component 20150724: root_PTN000817051 is found in nucleus (GO:0005634) 20150724: root_PTN000817051 is found in cytoplasm (GO:0005737) # biological_process 20150724: root_PTN000817051 participates in protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787) 20150724: Dictyostelium_PTN000817058 does NOT participate in apoptotic process (GO:0006915) 20150724: Embryophyta_PTN000817061 does NOT participate in apoptotic process (GO:0006915) 20150724: Embryophyta_PTN001618593 does NOT participate in apoptotic process (GO:0006915) 20150724: Tetrahymena thermophila SB210_Q23FX6 does NOT participate in apoptotic process (GO:0006915) 20150724: Tetrahymena thermophila SB210_Q23FX5 does NOT participate in apoptotic process (GO:0006915) 20150724: root_PTN000817051 participates in proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161) 20160813: Tetrahymena thermophila SB210_Q23FX6 does NOT participate in apoptotic process (GO:0006915) 20160813: Tetrahymena thermophila SB210_Q23FX5 does NOT participate in apoptotic process (GO:0006915) 20160813: Embryophyta_PTN001618593 does NOT participate in apoptotic process (GO:0006915) 20160813: Metazoa_PTN001618575 participates in apoptotic process (GO:0006915) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).