# HISTORY
24 Mar 2016: Updated by: TOUCHUP-v1.15
14 Mar 2016: Updated by: TOUCHUP-v1.12

# molecular_function

# cellular_component
20140211: Bilateria_PTN000033897 is found in integral component of synaptic vesicle membrane (GO:0030285) 

# biological_process
20140211: Euteleostomi_PTN000033951 participates in regulation of neuronal synaptic plasticity (GO:0048168) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
Synaptophysin and synaptoporin are synaptic vesicle proteins.
MF - Only mouse and rat synaptophysin genes are annotated as SH2 domain binding. No evidence of a particular function. Therefore, no MF is propagated
CC - Integral component of synaptic vesicle membran is propagated.
BP - No process can be propagated to the ancestor of all synaptophysin.  Mouse and rat SYP are involved in regulation of neuronal synaptic plasticity. Propagate to the root of Syp. It is not known whether Sypl are involved.

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).