# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.12 # molecular_function 20140930: Eumetazoa_PTN000813633 has function calcium-activated potassium channel activity (GO:0015269) 20140930: Eumetazoa_PTN000813633 has function potassium channel regulator activity (GO:0015459) # cellular_component 20140930: Eumetazoa_PTN000813633 is found in voltage-gated potassium channel complex (GO:0008076) # biological_process 20140930: Eumetazoa_PTN000813633 participates in detection of calcium ion (GO:0005513) 20140930: Eumetazoa_PTN000813633 participates in potassium ion transmembrane transport (GO:0071805) 20140930: Chordata_PTN000813636 participates in synaptic transmission (GO:0007268) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).