# HISTORY
24 Mar 2016: Updated by: TOUCHUP-v1.15
14 Mar 2016: Updated by: TOUCHUP-v1.12

# molecular_function
20150805: Eukaryota_PTN000028271 has function syntaxin binding (GO:0019905) 
20150805: Eukaryota_PTN000028271 has function Rab GTPase binding (GO:0017137) 
20150805: Eukaryota_PTN000028271 has function GTPase activator activity (GO:0005096) 
20150805: node_PTN000028341 has LOST/MODIFIED function syntaxin binding (GO:0019905) 

# cellular_component
20150805: Eukaryota_PTN000028271 is found in cytoplasm (GO:0005737) 
20150805: Eukaryota_PTN000028271 is found in plasma membrane (GO:0005886) 
20150805: Metazoa_PTN001614432 is found in secretory granule (GO:0030141) 
20150805: Metazoa_PTN001614432 is found in SNARE complex (GO:0031201) 
20150805: Metazoa_PTN001614445 is found in cortical actin cytoskeleton (GO:0030864) 

# biological_process
20150805: Eukaryota_PTN000028271 participates in regulation of exocytosis (GO:0017157) 
20150805: Opisthokonta_PTN000028273 participates in regulation of protein secretion (GO:0050708) 
20150805: Fungi_PTN000813047 participates in establishment of cell polarity (GO:0030010) 
20150805: Metazoa_PTN001614445 participates in regulation of establishment or maintenance of cell polarity (GO:0032878) 
20150805: Metazoa_PTN001614445 participates in establishment of spindle orientation (GO:0051294) 
20150805: Metazoa_PTN001614445 participates in neurogenesis (GO:0022008) 
20150805: Metazoa_PTN001614445 participates in cortical actin cytoskeleton organization (GO:0030866) 
20150805: Metazoa_PTN001614445 participates in regulation of Notch signaling pathway (GO:0008593) 
20150805: Metazoa_PTN001614445 does NOT participate in regulation of exocytosis (GO:0017157) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).