# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.12 # molecular_function 20141001: root_PTN000027542 has function protein kinase A binding (GO:0051018) # cellular_component 20141001: root_PTN000027542 is found in cytoplasm (GO:0005737) 20141001: Amniota_PTN001305121 is found in sperm principal piece (GO:0097228) 20141001: Amniota_PTN001305121 is found in sperm fibrous sheath (GO:0035686) 20141001: Amniota_PTN000027562 is found in sperm fibrous sheath (GO:0035686) 20141001: Amniota_PTN000027562 is found in sperm principal piece (GO:0097228) 20141001: Amniota_PTN001305135 is found in peroxisome (GO:0005777) 20141001: Euteleostomi_PTN000812494 is found in mitochondrion (GO:0005739) # biological_process 20141001: root_PTN000027542 participates in regulation of protein kinase A signaling (GO:0010738) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).