# HISTORY
07 May 2016: Updated by: TOUCHUP-v1.18
14 Mar 2016: Updated by: TOUCHUP-v1.12
24 Mar 2016: Updated by: TOUCHUP-v1.15

# molecular_function
20140815: root_PTN000021269 has function CXCR chemokine receptor binding (GO:0045236) 
20140815: root_PTN000021269 has function chemokine activity (GO:0008009) 
20140815: Boreoeutheria_PTN000021375 has function heparin binding (GO:0008201) 
20140815: Euteleostomi_PTN000021270 has function CXCR3 chemokine receptor binding (GO:0048248) 

# cellular_component
20140815: root_PTN000021269 is found in extracellular space (GO:0005615) 

# biological_process
20140815: root_PTN000021269 participates in G-protein coupled receptor signaling pathway (GO:0007186) 
20140815: root_PTN000021269 participates in inflammatory response (GO:0006954) 
20140815: root_PTN000021269 participates in chemokine-mediated signaling pathway (GO:0070098) 
20140815: root_PTN000021269 participates in positive regulation of leukocyte chemotaxis (GO:0002690) 
20140815: root_PTN000021269 participates in response to lipopolysaccharide (GO:0032496) 
20140815: root_PTN000021269 participates in immune response (GO:0006955) 
20140815: root_PTN000021269 participates in regulation of cell proliferation (GO:0042127) 
20140815: Amniota_PTN000021292 participates in B cell chemotaxis (GO:0035754) 
20140815: Boreoeutheria_PTN000021353 participates in neutrophil mediated immunity (GO:0002446) 
20140815: Amniota_PTN001303132 participates in positive regulation of neutrophil chemotaxis (GO:0090023) 
20140815: Euteleostomi_PTN000021270 participates in T cell chemotaxis (GO:0010818) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).