# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 14 Mar 2016: Updated by: TOUCHUP-v1.12 24 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150722: root_PTN001606015 has function phosphatase activity (GO:0016791) 20150722: Eumetazoa_PTN000807400 has function lipid phosphatase activity (GO:0042577) 20150722: Tetrapoda_PTN000018113 has function sphingosine-1-phosphate phosphatase activity (GO:0042392) 20150722: Eukaryota_PTN000017950 has function phosphatidate phosphatase activity (GO:0008195) # cellular_component 20150722: root_PTN001606015 is found in integral component of plasma membrane (GO:0005887) # biological_process 20150722: root_PTN001606015 participates in phospholipid dephosphorylation (GO:0046839) 20150722: root_PTN001606015 participates in phospholipid metabolic process (GO:0006644) 20150722: root_PTN001606015 participates in signal transduction (GO:0007165) 20150722: Euteleostomi_PTN000018009 participates in axonogenesis (GO:0007409) 20150722: Tetrapoda_PTN000018113 participates in canonical Wnt signaling pathway (GO:0060070) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).