# HISTORY 24 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.12 # molecular_function 20140730: root_PTN000010478 has function S-adenosylmethionine-dependent methyltransferase activity (GO:0008757) # cellular_component 20140730: root_PTN000010478 is found in cytoplasm (GO:0005737) 20140730: Eukaryota_PTN000010481 is found in mitochondrion (GO:0005739) 20140730: node_PTN000788014 is found in endosome (GO:0005768) 20140730: node_PTN000788014 is found in vacuolar membrane (GO:0005774) 20140730: node_PTN000788014 is found in trans-Golgi network (GO:0005802) # biological_process 20140730: root_PTN000010478 participates in methylation (GO:0032259) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).