# HISTORY 23 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.12 # molecular_function 20150814: root_PTN000801139 has function RNA polymerase II regulatory region sequence-specific DNA binding (GO:0000977) 20150814: root_PTN000801139 has function chromatin binding (GO:0003682) 20150814: root_PTN000801139 has function transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding (GO:0001228) 20150814: root_PTN000801139 has function RNA polymerase II transcription factor binding (GO:0001085) # cellular_component 20150814: root_PTN000801139 is found in transcription factor complex (GO:0005667) 20150814: root_PTN000801139 is found in nucleus (GO:0005634) # biological_process 20150814: root_PTN000801139 participates in cell differentiation (GO:0030154) 20150814: Metazoa_PTN001600558 participates in cell fate commitment (GO:0045165) 20150814: Metazoa_PTN001600558 participates in tissue development (GO:0009888) 20150814: Metazoa_PTN001600558 participates in digestive tract development (GO:0048565) 20150814: Metazoa_PTN001600558 participates in organ morphogenesis (GO:0009887) 20150814: Metazoa_PTN001600558 participates in heart development (GO:0007507) 20150814: Metazoa_PTN001600558 participates in cell development (GO:0048468) 20150814: Metazoa_PTN001600558 participates in anatomical structure formation involved in morphogenesis (GO:0048646) 20150814: Euteleostomi_PTN000007601 participates in positive regulation of BMP signaling pathway (GO:0030513) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).