# HISTORY
07 May 2016: Updated by: TOUCHUP-v1.18
14 Mar 2016: Updated by: TOUCHUP-v1.12
23 Mar 2016: Updated by: TOUCHUP-v1.15

# molecular_function
20140313: root_PTN000004140 has function cation channel activity (GO:0005261) 
20140313: Opisthokonta_PTN000798901 has function voltage-gated sodium channel activity (GO:0005248) 
20140313: Eukaryota_PTN000799132 has function voltage-gated calcium channel activity (GO:0005245) 
20140313: node_PTN000799133 has function NAADP-sensitive calcium-release channel activity (GO:0072345) 
20140313: node_PTN000799041 has function voltage-gated calcium channel activity (GO:0005245) 
20140319: node_PTN000004694 has function high voltage-gated calcium channel activity (GO:0008331) 

# cellular_component
20140313: root_PTN000004140 is found in plasma membrane (GO:0005886) 

# biological_process
20140319: root_PTN000004140 participates in membrane depolarization during action potential (GO:0086010) 
20140313: root_PTN000004140 participates in ion transmembrane transport (GO:0034220) 
20140313: Opisthokonta_PTN000798901 participates in neuronal action potential (GO:0019228) 
20140313: Eukaryota_PTN000799132 participates in calcium ion transport (GO:0006816) 
20140313: Eukaryota_PTN001295293 participates in calcium ion transport (GO:0006816) 
20140316: node_PTN000799041 participates in sperm motility (GO:0030317) 
20140319: node_PTN000004815 participates in positive regulation of calcium ion-dependent exocytosis (GO:0045956) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).