RNA Polymerase II CTD (phosphorylated) binds to CE
Activation of GT
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)
Capping complex formation
Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme
Formation of the CE:GMP intermediate complex
Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA
Dissociation of transcript with 5'-GMP from GT
Methylation of GMP-cap by RNA Methyltransferase
Recognition and binding of the mRNA cap by the cap-binding complex
Formation of cap binding complex (CBC)
mRNA Capping