KAT2B
PCAF
UniProt:Q92831 KAT2B
CTDP1
FCP1
UniProt:Q9Y5B0 CTDP1
Cleavage of mRNA at the 3'-end
Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA
Cleavage of the 3'-end of the Histone Pre-mRNA
Cleavage of Intronless Pre-mRNA at 3'-end
UBF-1 Binds rDNA Promoter
Phosphorylation of UBF-1:rDNA Promoter
Formation of SL1
Acetylation of SL1
Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter
Assembly of RNA Polymerase I Holoenzyme (human)
Binding of Rrn3 to RNA Polymerase I
Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter
Loss of Rrn3 from RNA Polymerase I promoter escape complex
Elongation of pre-rRNA transcript
TTF-I binds to the Sal Box
Polymerase I Transcription Complex/Nascent Pre rRNA Complex pauses at the TTF-I:Sal Box
PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box
Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box
RNA Polymerase III Abortive Initiation At Type 1 Open Promoters
RNA Polymerase III Abortive Initiation At Type 2 Open Promoters
RNA Polymerase III Abortive Initiation At Type 3 Open Promoters
RNA Polymerase III Productive Transcription
RNA Polymerase III Promoter Opening at Type 1 Promoters
RNA Polymerase III Promoter Opening at Type 2 Promoters
RNA Polymerase III Promoter Opening at Type 3 Promoters
RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites
RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters
RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters
RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters
RNA Polymerase III Termination and release of transcribed mRNA
RNA Polymerase III Transcriptional Pause at Terminator Sequence
Binding of TFIIIA To type 1 Promoter
Binding of TFIIIC to TFIIIA:Type I Promoter complex
Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex
Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex
Binding of TFIIIC to Type 2 promoter
Binding of TFIIIB to TFIIC: Type 2 Promoter Complex
Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex
Binding of SNAPc, Oct-1, and Staf to Type 3 Promoter
Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex
Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex
Initiation of RNA Polymerase III Productive Transcription
Resumption of RNA Polymerase III Productive Transcription
TFAM binds to mitochondrial promoters
Association of TFAM:mt promoter complex with POLRMT:TFB2M
Association of mTERF with the termination sequence
Abortive initiation after formation of the first phosphodiester bond
Abortive Initiation After Second Transition
Abortive Initiation Before Second Transition
Formation of DSIF complex
Formation of Elongin BC complex
Formation of FACT complex
Formation of NELF complex
Formation of P-TEFb complex
Formation of elongin complex
Resumption of elongation after recovery from pausing
2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing
7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest
TFIIS-mediated recovery of elongation from arrest
Abortive termination of early transcription elongation by DSIF:NELF
Abortive termination of elongation after arrest
Elongating transcript encounters a lesion in the template
Fall Back to Closed Pre-initiation Complex
Recognition and Binding of Core Promoter Elements by TFIID
Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex
Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex
Binding of TFIIE to the growing preinitiation complex
Formation of the closed pre-initiation complex
RNA Polymerase II Promoter Opening: First Transition
NTP Binds Active Site of RNA Polymerase II
Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP
Newly Formed Phosphodiester Bond Stabilized and PPi Released
Addition of the third nucleotide on the nascent transcript
Addition of the fourth nucleotide on the Nascent Transcript: Second Transition
Addition of Nucleotides 5 through 9 on the growing Transcript
Addition of nucleotides 10 and 11 on the growing transcript: Third Transition
Addition of nucleotides between position +11 and +30
Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex
Phosphorylation (Ser5) of RNA pol II CTD
RNA Polymerase II CTD (phosphorylated) binds to CE
Activation of GT
SPT5 subunit of Pol II binds the RNA triphosphatase (RTP)
Hypophosphorylation of RNA Pol II CTD by FCP1P protein
DSIF complex binds to RNA Pol II (hypophosphorylated)
Formation of DSIF:NELF:early elongation complex
Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex
Recruitment of elongation factors to form elongation complex
Addition of nucleotides leads to transcript elongation
Pol II elongation complex moves on the template as transcript elongates
Separation of elongating transcript from template
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription
RNA Polymerase I Promoter Clearance
RNA Polymerase I Promoter Opening
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase I Transcription Termination
RNA Polymerase III Transcription
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription Termination
Transcription from mitochondrial promoters
Mitochondrial transcription initiation
POLRMT chain elongation
Mitochondrial transcription termination
RNA Polymerase II Transcription
RNA Polymerase II Pre-transcription Events
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase II Transcription Initiation
RNA Polymerase II Promoter Escape
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Transcription Elongation
Formation of the Early Elongation Complex
Formation of RNA Pol II elongation complex
RNA Polymerase II Transcription Termination
Cleavage of Growing Transcript in the Termination Region
Transcription