@prefix    owl: <http://www.w3.org/2002/07/owl#> .
@prefix   rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix    rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix biopax: <http://www.reactome.org/biopax/48887#> .
@prefix    obo: <http://purl.obolibrary.org/obo/> .

# Named toplevel resources (10)

<http://example.org>
	a owl:Ontology ;
	owl:imports <http://purl.obolibrary.org/obo/go.owl> ,
		    <http://purl.obolibrary.org/obo/go/extensions/lego-relations.owl> .

obo:UniProtKB_P25774
	rdfs:label "CTSS"@em ,
		   "UniProt:P25774 CTSS"@em .

biopax:BiochemicalReaction854
	a obo:GO_0003674 ;
	obo:BFO_0000050 biopax:Pathway244 ;
	obo:directly_activates biopax:BiochemicalReaction855 ;
	rdfs:label "TLR folding by chaperones GP96 and CNPY3"@em .

biopax:BiochemicalReaction855
	a obo:GO_0003674 ;
	obo:BFO_0000050 biopax:Pathway244 ;
	obo:directly_activates biopax:BiochemicalReaction856 ;
	rdfs:label "Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex"@em .

biopax:BiochemicalReaction856
	a obo:GO_0003674 ;
	obo:BFO_0000050 biopax:Pathway244 ;
	obo:directly_activates biopax:BiochemicalReaction857 ;
	rdfs:label "Full-length TLR3/7/8/9 binds to UNC93B1"@em .

biopax:BiochemicalReaction857
	a obo:GO_0003674 ;
	obo:BFO_0000050 biopax:Pathway244 ;
	obo:directly_activates biopax:BiochemicalReaction858 ;
	rdfs:label "Endosomal TLRs pass through the Golgi"@em .

biopax:BiochemicalReaction858
	a obo:GO_0003674 ;
	obo:BFO_0000050 biopax:Pathway244 ;
	obo:directly_activates biopax:BiochemicalReaction859 ,
			       biopax:BiochemicalReaction860 ,
			       biopax:Catalysis324 ,
			       biopax:Catalysis325 ,
			       biopax:Control53 ;
	rdfs:label "UNC93B1 delivers endosomal full-length TLRs to endolysosome"@em .

biopax:BiochemicalReaction859
	a [ a owl:Restriction ;
	    owl:onProperty obo:BFO_0000066 ;
	    owl:someValuesFrom obo:GO_0036021
	  ] ,
	  obo:GO_0004197 ;
	obo:BFO_0000050 biopax:Pathway244 ;
	obo:directly_activates biopax:BiochemicalReaction972 ,
			       biopax:Control68 ;
	rdfs:label "TLR processing at low pH"@em .

biopax:BiochemicalReaction860
	a [ a owl:Restriction ;
	    owl:onProperty obo:BFO_0000066 ;
	    owl:someValuesFrom obo:GO_0036021
	  ] ,
	  [ a owl:Restriction ;
	    owl:onProperty obo:enabled_by ;
	    owl:someValuesFrom obo:UniProtKB_P25774
	  ] ,
	  obo:GO_0004197 ;
	obo:BFO_0000050 biopax:Pathway244 ;
	obo:directly_activates biopax:BiochemicalReaction970 ,
			       biopax:BiochemicalReaction971 ,
			       biopax:Control67 ;
	rdfs:label "TLR9 processing at neutral pH"@em .

biopax:Pathway244
	a obo:GO_0008150 ;
	rdfs:label "Trafficking and processing of endosomal TLR"@em .