PPM1A
label: PPPM1A
label: UniProt:P35813 PPM1A

LKB1 forms a trimeric complex with STRAD and MO25
type: GO_0003674
BFO_0000050: Regulation of AMPK activity via LKB1
directly activates: Activation of cytosolic AMPK by phosphorylation
directly activates: Catalysis1749
directly activates: Control309
directly activates: Control310

Activation of cytosolic AMPK by phosphorylation
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004674
BFO_0000050: Regulation of AMPK activity via LKB1
directly activates: AMPK is dephosphorylated
directly activates: Phosphorylated AMPK binds AMP
directly activates: BiochemicalReaction4768
directly activates: Catalysis1750
directly activates: Catalysis2124

AMPK is dephosphorylated
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: Restriction
  on property: enabled by
  some values from: PPM1A
type: GO_0004722
BFO_0000050: Regulation of AMPK activity via LKB1

Phosphorylated AMPK binds AMP
type: GO_0003674
BFO_0000050: Regulation of AMPK activity via LKB1
directly activates: AMPK phosphorylates Raptor
directly activates: BiochemicalReaction3839
directly activates: BiochemicalReaction4768
directly activates: BiochemicalReaction5359
directly activates: Catalysis1751
directly activates: Catalysis1752
directly activates: Catalysis2124
directly activates: Catalysis2580
directly activates: Control435
directly activates: Control436

AMPK phosphorylates Raptor
type: Restriction
  on property: BFO_0000066
  some values from: GO_0005829
type: GO_0004679
BFO_0000050: Regulation of AMPK activity via LKB1

Regulation of AMPK activity via LKB1
type: GO_0008150