@prefix    owl: <http://www.w3.org/2002/07/owl#> .
@prefix   rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix    rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix biopax: <http://www.reactome.org/biopax/48887#> .
@prefix    obo: <http://purl.obolibrary.org/obo/> .

# Named toplevel resources (7)

<http://example.org>
	a owl:Ontology ;
	owl:imports <http://purl.obolibrary.org/obo/go.owl> ,
		    <http://purl.obolibrary.org/obo/go/extensions/lego-relations.owl> .

obo:UniProtKB_P24557
	rdfs:label "CYP5"@em ,
		   "CYP5A1"@em ,
		   "TBXAS1"@em ,
		   "UniProt:P24557 TBXAS1"@em .

biopax:BiochemicalReaction5215
	a [ a owl:Restriction ;
	    owl:onProperty obo:BFO_0000066 ;
	    owl:someValuesFrom obo:GO_0005789
	  ] ,
	  obo:GO_0008116 ;
	obo:BFO_0000050 biopax:Pathway1337 ;
	obo:directly_activates biopax:BiochemicalReaction5216 ;
	rdfs:label "PGH2 is isomerised to PGI2 by PTGIS"@em ,
		   "Prostacyclin synthase (CYP8A1) mediates the isomerization of prostaglandin H2 to prostaglandin I2"@em .

biopax:BiochemicalReaction5217
	a [ a owl:Restriction ;
	    owl:onProperty obo:BFO_0000066 ;
	    owl:someValuesFrom obo:GO_0005789
	  ] ,
	  [ a owl:Restriction ;
	    owl:onProperty obo:enabled_by ;
	    owl:someValuesFrom obo:UniProtKB_P24557
	  ] ,
	  obo:GO_0004796 ;
	obo:BFO_0000050 biopax:Pathway1337 ;
	obo:directly_activates biopax:BiochemicalReaction5218 ;
	rdfs:label "PGH2 is isomerised to TXA2 by TBXAS1"@em ,
		   "Thromboxane synthase (CYP5A1) mediates the isomerization of prostaglandin H2 to thromboxane A2"@em .

biopax:BiochemicalReaction5226
	a [ a owl:Restriction ;
	    owl:onProperty obo:BFO_0000066 ;
	    owl:someValuesFrom obo:GO_0005789
	  ] ,
	  obo:GO_0050051 ;
	obo:BFO_0000050 biopax:Pathway1337 ;
	obo:directly_activates biopax:BiochemicalReaction5227 ,
			       biopax:Catalysis2477 ;
	rdfs:label "CYP4F2 omega-hydroxylates leukotriene B4, thus inactivating it"@em ,
		   "LTB4 is hydroxylated to 20oh-LTB4 by CYP4F2/4F3"@em .

biopax:BiochemicalReaction5870
	a [ a owl:Restriction ;
	    owl:onProperty obo:BFO_0000066 ;
	    owl:someValuesFrom obo:GO_0005789
	  ] ,
	  obo:GO_0019825 ;
	obo:BFO_0000050 biopax:Pathway1337 ;
	rdfs:label "CYP4F8 hydroxylates prostaglandin H2"@em .

biopax:Pathway1337
	a obo:GO_0008150 ;
	rdfs:label "Eicosanoids"@em .