@prefix    owl: <http://www.w3.org/2002/07/owl#> .
@prefix   rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix    rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix biopax: <http://www.reactome.org/biopax/48887#> .
@prefix    obo: <http://purl.obolibrary.org/obo/> .

# Named toplevel resources (8)

<http://example.org>
	a owl:Ontology ;
	owl:imports <http://purl.obolibrary.org/obo/go.owl> ,
		    <http://purl.obolibrary.org/obo/go/extensions/lego-relations.owl> .

obo:UniProtKB_Q92888
	rdfs:label "ARHGEF1"@em ,
		   "UniProt:Q92888 ARHGEF1"@em .

biopax:BiochemicalReaction3901
	a obo:GO_0003674 ;
	obo:BFO_0000050 biopax:Pathway1002 ;
	obo:directly_activates biopax:BiochemicalReaction3902 ;
	rdfs:label "p75NTR interacts with the NOGO receptor"@em .

biopax:BiochemicalReaction3902
	a obo:GO_0003674 ;
	obo:BFO_0000050 biopax:Pathway1002 ;
	obo:directly_activates biopax:BiochemicalReaction3903 ;
	rdfs:label "p75NTR:NgR complex interacts with the axonal inhibitor LINGO1"@em .

biopax:BiochemicalReaction3903
	a obo:GO_0003674 ;
	obo:BFO_0000050 biopax:Pathway1002 ;
	obo:directly_activates biopax:BiochemicalReaction3904 ;
	rdfs:label "Myelin components can interact with p75NTR:NgR:LINGO1"@em .

biopax:BiochemicalReaction3904
	a obo:GO_0003674 ;
	obo:BFO_0000050 biopax:Pathway1002 ;
	obo:directly_activates biopax:BiochemicalReaction3905 ,
			       biopax:Catalysis1778 ;
	rdfs:label "The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA"@em .

biopax:BiochemicalReaction3905
	a [ a owl:Restriction ;
	    owl:onProperty obo:BFO_0000066 ;
	    owl:someValuesFrom obo:GO_0005886
	  ] ,
	  [ a owl:Restriction ;
	    owl:onProperty obo:enabled_by ;
	    owl:someValuesFrom obo:UniProtKB_Q92888
	  ] ,
	  obo:GO_0005089 ;
	obo:BFO_0000050 biopax:Pathway1002 ;
	rdfs:label "RhoA is activated by nucleotide exchange and inhibits axonal growth"@em .

biopax:Pathway1002
	a obo:GO_0008150 ;
	rdfs:label "Axonal growth inhibition (RHOA activation)"@em .