'Protein_Id'	'sf_name'	'definition'	'organism'	'gene_id'	'gene_symbol'	'Molecular function'	'Biological process'	'Cellular component'	'Protein class'	'Public_node_id'
'AN68'	'INSULIN RECEPTOR SUBSTRATE 2'	''	''	''	''	'GO:0005515=protein binding;GO:0005102=receptor binding;GO:0004871=signal transducer activity;GO:0005488=binding'	'GO:0008152=metabolic process;GO:0007165=signal transduction;GO:0050789=regulation of biological process;GO:0007154=cell communication;GO:0007166=cell surface receptor signaling pathway;GO:0007169=transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009719=response to endogenous stimulus;GO:0050896=response to stimulus;GO:0044238=primary metabolic process;GO:0009987=cellular process;GO:0065007=biological regulation;GO:0006629=lipid metabolic process'	'GO:0016020=membrane;GO:0005829=cytosol;GO:0044464=cell part;GO:0005622=intracellular;GO:0005886=plasma membrane;GO:0005737=cytoplasm'	''	'PTN000064811'
'MOUSE|MGI=MGI=109334|UniProtKB=P81122'	''	'Insulin receptor substrate 2'	'Mus musculus'	'MGI:MGI=109334'	'Irs2'	''	''	''	''	'PTN000064825'
'HORSE|Ensembl=ENSECAG00000003315|UniProtKB=F6X610'	''	'Uncharacterized protein (Fragment)'	'Equus caballus'	'Ensembl:ENSECAG00000003315'	'IRS2'	''	''	''	''	'PTN002239247'
'XENTR|Ensembl=ENSXETG00000002647|UniProtKB=F6TDY1'	''	'Uncharacterized protein (Fragment)'	'Xenopus tropicalis'	'Ensembl:ENSXETG00000002647'	'LOC100498409'	''	''	''	''	'PTN000064834'
'FELCA|Ensembl=ENSFCAG00000025305|UniProtKB=M3WWW7'	''	'Uncharacterized protein (Fragment)'	'Felis catus'	'Ensembl:ENSFCAG00000025305'	'IRS2'	''	''	''	''	'PTN001635342'
'PANTR|Ensembl=ENSPTRG00000006030|UniProtKB=H2Q7S8'	''	'Uncharacterized protein (Fragment)'	'Pan troglodytes'	'Ensembl:ENSPTRG00000006030'	'IRS2'	''	''	''	''	'PTN000064822'
'ANOCA|Ensembl=ENSACAG00000008078|UniProtKB=H9GDE9'	''	'Uncharacterized protein'	'Anolis carolinensis'	'Ensembl:ENSACAG00000008078'	'LOC103282162'	''	''	''	''	'PTN001635344'
'TAKRU|Ensembl=ENSTRUG00000009972|UniProtKB=H2TK86'	''	'Uncharacterized protein'	'Takifugu rubripes'	'Ensembl:ENSTRUG00000009972'	'LOC101076043'	''	''	''	''	'PTN001635337'
'CANFA|Ensembl=ENSCAFG00000006058|UniProtKB=F1Q219'	''	'Uncharacterized protein (Fragment)'	'Canis familiaris'	'Ensembl:ENSCAFG00000006058'	'IRS2'	''	''	''	''	'PTN000064831'
'CHICK|Ensembl=ENSGALG00000016839|UniProtKB=F1P2R4'	''	'Uncharacterized protein (Fragment)'	'Gallus gallus'	'Ensembl:ENSGALG00000016839'	'IRS2'	''	''	''	''	'PTN001635345'
'DANRE|ZFIN=ZDB-GENE-040426-975|UniProtKB=F1QHL0'	''	'Uncharacterized protein'	'Danio rerio'	'ZFIN:ZDB-GENE-040426-975'	'irs2a'	''	''	''	''	'PTN000064839'
'RAT|RGD=69316|UniProtKB=F1MAL5'	''	'Protein Irs2'	'Rattus norvegicus'	'RGD:69316'	'Irs2'	''	''	''	''	'PTN000064827'
'MONDO|Ensembl=ENSMODG00000004825|UniProtKB=F6RR27'	''	'Uncharacterized protein (Fragment)'	'Monodelphis domestica'	'Ensembl:ENSMODG00000004825'	'IRS2'	''	''	''	''	'PTN001318340'
'MACMU|Ensembl=ENSMMUG00000021790|UniProtKB=F7DE94'	''	'Uncharacterized protein (Fragment)'	'Macaca mulatta'	'Ensembl:ENSMMUG00000021790'	'IRS2'	''	''	''	''	'PTN000064823'
'HUMAN|HGNC=6126|UniProtKB=Q9Y4H2'	''	'Insulin receptor substrate 2'	'Homo sapiens'	'HGNC:6126'	'IRS2'	''	''	''	''	'PTN000064819'
'BOVIN|Ensembl=ENSBTAG00000012019|UniProtKB=F1MJE0'	''	'Uncharacterized protein (Fragment)'	'Bos taurus'	'Ensembl:ENSBTAG00000012019'	'IRS2'	''	''	''	''	'PTN000064830'
'TAKRU|Ensembl=ENSTRUG00000006418|UniProtKB=H2STH6'	''	'Uncharacterized protein'	'Takifugu rubripes'	'Ensembl:ENSTRUG00000006418'	'IRS2 (1 of 2)'	''	''	''	''	'PTN000064838'
'AN5'	'INSULIN RECEPTOR SUBSTRATE 1'	''	''	''	''	'GO:0005515=protein binding;GO:0005102=receptor binding;GO:0004871=signal transducer activity;GO:0005488=binding'	'GO:0008152=metabolic process;GO:0007165=signal transduction;GO:0050789=regulation of biological process;GO:0007154=cell communication;GO:0007166=cell surface receptor signaling pathway;GO:0007169=transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009719=response to endogenous stimulus;GO:0050896=response to stimulus;GO:0044238=primary metabolic process;GO:0009987=cellular process;GO:0065007=biological regulation;GO:0006629=lipid metabolic process'	'GO:0016020=membrane;GO:0005829=cytosol;GO:0044464=cell part;GO:0005622=intracellular;GO:0005886=plasma membrane;GO:0005737=cytoplasm'	''	'PTN000064840'
'PANTR|Ensembl=ENSPTRG00000012989|UniProtKB=H2QJJ4'	''	'Insulin receptor substrate 1'	'Pan troglodytes'	'Ensembl:ENSPTRG00000012989'	'IRS1'	''	''	''	''	'PTN000064849'
'RAT|RGD=2922|UniProtKB=P35570'	''	'Insulin receptor substrate 1'	'Rattus norvegicus'	'RGD:2922'	'Irs1'	''	''	''	''	'PTN000064857'
'CANFA|Ensembl=ENSCAFG00000010397|UniProtKB=E2RDB5'	''	'Uncharacterized protein (Fragment)'	'Canis familiaris'	'Ensembl:ENSCAFG00000010397'	'IRS1'	''	''	''	''	'PTN000064860'
'ANOCA|Ensembl=ENSACAG00000003830|UniProtKB=G1KC98'	''	'Uncharacterized protein'	'Anolis carolinensis'	'Ensembl:ENSACAG00000003830'	'IRS1'	''	''	''	''	'PTN001318350'
'MACMU|Ensembl=ENSMMUG00000019467|UniProtKB=F6SUL3'	''	'Uncharacterized protein'	'Macaca mulatta'	'Ensembl:ENSMMUG00000019467'	'IRS4'	''	''	''	''	'PTN000064850'
'BOVIN|Ensembl=ENSBTAG00000021308|UniProtKB=F1MYE0'	''	'Uncharacterized protein'	'Bos taurus'	'Ensembl:ENSBTAG00000021308'	'IRS1'	''	''	''	''	'PTN000064859'
'HORSE|Ensembl=ENSECAG00000007393|UniProtKB=F7DIR1'	''	'Uncharacterized protein'	'Equus caballus'	'Ensembl:ENSECAG00000007393'	'IRS1'	''	''	''	''	'PTN001318348'
'HUMAN|HGNC=6125|UniProtKB=P35568'	''	'Insulin receptor substrate 1'	'Homo sapiens'	'HGNC:6125'	'IRS1'	''	''	''	''	'PTN000064848'
'XENTR|Gene=Xenbase=XB-GENE-6455904|UniProtKB=Q6P4Y6'	''	'Insulin receptor substrate 1'	'Xenopus tropicalis'	'Gene:Xenbase=XB-GENE-6455904'	'irs1'	''	''	''	''	'PTN001635347'
'CHICK|Ensembl=ENSGALG00000004959|UniProtKB=F1NIJ3'	''	'Uncharacterized protein (Fragment)'	'Gallus gallus'	'Ensembl:ENSGALG00000004959'	'IRS1'	''	''	''	''	'PTN001635332'
'MONDO|Ensembl=ENSMODG00000021208|UniProtKB=F7B223'	''	'Uncharacterized protein'	'Monodelphis domestica'	'Ensembl:ENSMODG00000021208'	'IRS1'	''	''	''	''	'PTN000064861'
'MOUSE|MGI=MGI=99454|UniProtKB=P35569'	''	'Insulin receptor substrate 1'	'Mus musculus'	'MGI:MGI=99454'	'Irs1'	''	''	''	''	'PTN000064856'
'PIG|Ensembl=ENSSSCG00000025729|UniProtKB=I3LLF1'	''	'Uncharacterized protein'	'Sus scrofa'	'Ensembl:ENSSSCG00000025729'	'IRS1'	''	''	''	''	'PTN001318347'
'DANRE|ZFIN=ZDB-GENE-030131-872|UniProtKB=E7F4P8'	''	'Uncharacterized protein'	'Danio rerio'	'ZFIN:ZDB-GENE-030131-872'	'irs1'	''	''	''	''	'PTN000834856'
'FELCA|Ensembl=ENSFCAG00000003009|UniProtKB=M3WUW8'	''	'Uncharacterized protein'	'Felis catus'	'Ensembl:ENSFCAG00000003009'	'IRS1'	''	''	''	''	'PTN001635331'
'AN73'	'SUBFAMILY NOT NAMED'	''	''	''	''	'GO:0005515=protein binding;GO:0005102=receptor binding;GO:0004871=signal transducer activity;GO:0005488=binding'	'GO:0008152=metabolic process;GO:0007165=signal transduction;GO:0050789=regulation of biological process;GO:0007154=cell communication;GO:0007166=cell surface receptor signaling pathway;GO:0007169=transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009719=response to endogenous stimulus;GO:0050896=response to stimulus;GO:0044238=primary metabolic process;GO:0009987=cellular process;GO:0065007=biological regulation;GO:0006629=lipid metabolic process'	'GO:0016020=membrane;GO:0005829=cytosol;GO:0044464=cell part;GO:0005622=intracellular;GO:0005886=plasma membrane;GO:0005737=cytoplasm'	''	'PTN000834850'
'HORSE|Ensembl=ENSECAG00000022553|UniProtKB=F7B2X2'	''	'Uncharacterized protein (Fragment)'	'Equus caballus'	'Ensembl:ENSECAG00000022553'	'LOC100069009'	''	''	''	''	'PTN001318344'
'MOUSE|MGI=MGI=1194882|UniProtKB=O54718'	''	'Insulin receptor substrate 3, isoform CRA_a (Fragment)'	'Mus musculus'	'MGI:MGI=1194882'	'Irs3'	''	''	''	''	'PTN000834852'
'BOVIN|Ensembl=ENSBTAG00000046753|UniProtKB=G3N0N9'	''	'Uncharacterized protein'	'Bos taurus'	'Ensembl:ENSBTAG00000046753'	'LOC532330'	''	''	''	''	'PTN000834854'
'PIG|Ensembl=ENSSSCG00000007665|UniProtKB=F1RMY3'	''	'Uncharacterized protein'	'Sus scrofa'	'Ensembl:ENSSSCG00000007665'	'LOC100515824'	''	''	''	''	'PTN001318343'
'RAT|RGD=69317|UniProtKB=B1WBQ1'	''	'Insulin receptor substrate 3'	'Rattus norvegicus'	'RGD:69317'	'Irs3'	''	''	''	''	'PTN000834853'
'FELCA|Ensembl=ENSFCAG00000026820|UniProtKB=M3X4G3'	''	'Uncharacterized protein'	'Felis catus'	'Ensembl:ENSFCAG00000026820'	'LOC101100432'	''	''	''	''	'PTN001635340'
'AN37'	'SUBFAMILY NOT NAMED'	''	''	''	''	'GO:0005515=protein binding;GO:0005102=receptor binding;GO:0004871=signal transducer activity;GO:0005488=binding'	'GO:0008152=metabolic process;GO:0007165=signal transduction;GO:0050789=regulation of biological process;GO:0007154=cell communication;GO:0007166=cell surface receptor signaling pathway;GO:0007169=transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009719=response to endogenous stimulus;GO:0050896=response to stimulus;GO:0044238=primary metabolic process;GO:0009987=cellular process;GO:0065007=biological regulation;GO:0006629=lipid metabolic process'	'GO:0016020=membrane;GO:0005829=cytosol;GO:0044464=cell part;GO:0005622=intracellular;GO:0005886=plasma membrane;GO:0005737=cytoplasm'	''	'PTN000064872'
'TAKRU|Ensembl=ENSTRUG00000016413|UniProtKB=H2UYD0'	''	'Uncharacterized protein (Fragment)'	'Takifugu rubripes'	'Ensembl:ENSTRUG00000016413'	''	''	''	''	''	'PTN000064873'
'DANRE|ZFIN=ZDB-GENE-060526-161|UniProtKB=A2BFQ2'	''	'Uncharacterized protein'	'Danio rerio'	'ZFIN:ZDB-GENE-060526-161'	'si:ch211-284e13.4'	''	''	''	''	'PTN000064874'
'AN41'	'INSULIN RECEPTOR SUBSTRATE 4'	''	''	''	''	'GO:0005515=protein binding;GO:0005102=receptor binding;GO:0004871=signal transducer activity;GO:0005488=binding'	'GO:0008152=metabolic process;GO:0007165=signal transduction;GO:0050789=regulation of biological process;GO:0007154=cell communication;GO:0007166=cell surface receptor signaling pathway;GO:0007169=transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009719=response to endogenous stimulus;GO:0050896=response to stimulus;GO:0044238=primary metabolic process;GO:0009987=cellular process;GO:0065007=biological regulation;GO:0006629=lipid metabolic process'	'GO:0016020=membrane;GO:0005829=cytosol;GO:0044464=cell part;GO:0005622=intracellular;GO:0005886=plasma membrane;GO:0005737=cytoplasm'	''	'PTN000064876'
'BOVIN|Ensembl=ENSBTAG00000006535|UniProtKB=F1MGG8'	''	'Uncharacterized protein'	'Bos taurus'	'Ensembl:ENSBTAG00000006535'	'IRS4'	''	''	''	''	'PTN000064886'
'XENTR|Gene=Xenbase=XB-GENE-479893|UniProtKB=F6YCQ0'	''	'Uncharacterized protein'	'Xenopus tropicalis'	'Gene:Xenbase=XB-GENE-479893'	'irs4'	''	''	''	''	'PTN000064889'
'HORSE|Ensembl=ENSECAG00000011649|UniProtKB=F7BFW6'	''	'Uncharacterized protein (Fragment)'	'Equus caballus'	'Ensembl:ENSECAG00000011649'	'IRS4'	''	''	''	''	'PTN001318334'
'TAKRU|Ensembl=ENSTRUG00000009726|UniProtKB=H2TID3'	''	'Uncharacterized protein (Fragment)'	'Takifugu rubripes'	'Ensembl:ENSTRUG00000009726'	'LOC101074788'	''	''	''	''	'PTN000064891'
'DANRE|Ensembl=ENSDARG00000052065|UniProtKB=F1R988'	''	'Uncharacterized protein (Fragment)'	'Danio rerio'	'Ensembl:ENSDARG00000052065'	''	''	''	''	''	'PTN000064892'
'HUMAN|HGNC=6128|UniProtKB=O14654'	''	'Insulin receptor substrate 4'	'Homo sapiens'	'HGNC:6128'	'IRS4'	''	''	''	''	'PTN000064882'
'CHICK|Ensembl=ENSGALG00000008107|UniProtKB=F1NDQ2'	''	'Uncharacterized protein'	'Gallus gallus'	'Ensembl:ENSGALG00000008107'	'IRS4'	''	''	''	''	'PTN001635335'
'MONDO|Ensembl=ENSMODG00000011507|UniProtKB=F6V0Y2'	''	'Uncharacterized protein'	'Monodelphis domestica'	'Ensembl:ENSMODG00000011507'	'IRS4'	''	''	''	''	'PTN001318335'
'DANRE|ZFIN=ZDB-GENE-120215-92|UniProtKB=E7FCJ4'	''	'Uncharacterized protein'	'Danio rerio'	'ZFIN:ZDB-GENE-120215-92'	'irs4a'	''	''	''	''	'PTN000834848'
'MOUSE|MGI=MGI=1338009|UniProtKB=Q9Z0Y7'	''	'Insulin receptor substrate 4'	'Mus musculus'	'MGI:MGI=1338009'	'Irs4'	''	''	''	''	'PTN000064884'
'FELCA|Ensembl=ENSFCAG00000000760|UniProtKB=M3VVC7'	''	'Uncharacterized protein (Fragment)'	'Felis catus'	'Ensembl:ENSFCAG00000000760'	'IRS4'	''	''	''	''	'PTN001635334'
'PIG|Ensembl=ENSSSCG00000031027|UniProtKB=K7GKX4'	''	'Uncharacterized protein'	'Sus scrofa'	'Ensembl:ENSSSCG00000031027'	'LOC100622674'	''	''	''	''	'PTN001318333'
'ANOCA|Ensembl=ENSACAG00000012623|UniProtKB=H9GJ30'	''	'Uncharacterized protein'	'Anolis carolinensis'	'Ensembl:ENSACAG00000012623'	'IRS4'	''	''	''	''	'PTN001318337'
'CANFA|Ensembl=ENSCAFG00000018028|UniProtKB=E2RLU4'	''	'Uncharacterized protein'	'Canis familiaris'	'Ensembl:ENSCAFG00000018028'	'IRS4'	''	''	''	''	'PTN000064887'
'AN34'	'SUBFAMILY NOT NAMED'	''	''	''	''	'GO:0005515=protein binding;GO:0005102=receptor binding;GO:0004871=signal transducer activity;GO:0005488=binding'	'GO:0008152=metabolic process;GO:0007165=signal transduction;GO:0050789=regulation of biological process;GO:0007154=cell communication;GO:0007166=cell surface receptor signaling pathway;GO:0007169=transmembrane receptor protein tyrosine kinase signaling pathway;GO:0009719=response to endogenous stimulus;GO:0050896=response to stimulus;GO:0044238=primary metabolic process;GO:0009987=cellular process;GO:0065007=biological regulation;GO:0006629=lipid metabolic process'	'GO:0016020=membrane;GO:0005829=cytosol;GO:0044464=cell part;GO:0005622=intracellular;GO:0005886=plasma membrane;GO:0005737=cytoplasm'	''	'PTN000064869'
'TAKRU|Ensembl=ENSTRUG00000013464|UniProtKB=H2UBL4'	''	'Uncharacterized protein'	'Takifugu rubripes'	'Ensembl:ENSTRUG00000013464'	'IRS4 (1 of 2)'	''	''	''	''	'PTN000064870'
'DANRE|Ensembl=ENSDARG00000036414|UniProtKB=E7F0F4'	''	'Uncharacterized protein'	'Danio rerio'	'Ensembl:ENSDARG00000036414'	'CU019646.1'	''	''	''	''	'PTN000064871'
'AN0'	'INSULIN RECEPTOR SUBSTRATE 1'	''	''	''	''	''	''	''	''	'PTN001635327'
'IXOSC|EnsemblGenome=ISCW021008|UniProtKB=B7Q4T8'	''	'Putative uncharacterized protein'	'Ixodes scapularis'	'EnsemblGenome:ISCW021008'	'IscW_ISCW021008'	''	''	''	''	'PTN000834865'
'BRAFL|Gene=BRAFLDRAFT_109853|UniProtKB=C3ZZ55'	''	'Putative uncharacterized protein'	'Branchiostoma floridae'	'Gene:BRAFLDRAFT_109853'	'BRAFLDRAFT_109853'	''	''	''	''	'PTN001635348'
'TRIAD|EnsemblGenome=TriadG27870|UniProtKB=B3S160'	''	'Putative uncharacterized protein'	'Trichoplax adhaerens'	'EnsemblGenome:TriadG27870'	'TRIADDRAFT_27870'	''	''	''	''	'PTN001635325'
'NEMVE|Gene=v1g92099|UniProtKB=A7RST3'	''	'Predicted protein (Fragment)'	'Nematostella vectensis'	'Gene:v1g92099'	'v1g92099'	''	''	''	''	'PTN001635328'
'BRAFL|Gene=BRAFLDRAFT_87265|UniProtKB=C3ZU03'	''	'Putative uncharacterized protein'	'Branchiostoma floridae'	'Gene:BRAFLDRAFT_87265'	'BRAFLDRAFT_87265'	''	''	''	''	'PTN001635349'
'DAPPU|EnsemblGenome=DAPPUDRAFT_52188|UniProtKB=E9GLG7'	''	'Putative insulin receptor substrate (Fragment)'	'Daphnia pulex'	'EnsemblGenome:DAPPUDRAFT_52188'	'DAPPUDRAFT_52188'	''	''	''	''	'PTN002239248'
'BRAFL|Gene=BRAFLDRAFT_132514|UniProtKB=C3ZZ54'	''	'Putative uncharacterized protein'	'Branchiostoma floridae'	'Gene:BRAFLDRAFT_132514'	'BRAFLDRAFT_132514'	''	''	''	''	'PTN000834858'
'BRAFL|Gene=BRAFLDRAFT_124878|UniProtKB=C3ZU02'	''	'Putative uncharacterized protein'	'Branchiostoma floridae'	'Gene:BRAFLDRAFT_124878'	'BRAFLDRAFT_124878'	''	''	''	''	'PTN000834859'
'STRPU|EnsemblGenome=SPU_011063|UniProtKB=W4Y5R5'	''	'Uncharacterized protein'	'Strongylocentrotus purpuratus'	'EnsemblGenome:SPU_011063'	'Sp-Irs1'	''	''	''	''	'PTN001635350'
'DROME|FlyBase=FBgn0024248|UniProtKB=Q9XTN2'	''	'Insulin receptor substrate 1'	'Drosophila melanogaster'	'FlyBase:FBgn0024248'	'chico'	''	''	''	''	'PTN000064893'
'TRIAD|EnsemblGenome=TriadG28050|UniProtKB=B3S138'	''	'Putative uncharacterized protein'	'Trichoplax adhaerens'	'EnsemblGenome:TriadG28050'	'TRIADDRAFT_28050'	''	''	''	''	'PTN001635326'