GO Monthly Release Notes for January 2004
========================
Generated on Wed Feb 11 10:58:30 2004
Files used:
component old: 2.440 new: 2.446
function old: 2.930 new: 2.944
process old: 2.1069 new: 2.1102
definitions old: 2.1586 new: 2.1627
GO Slim: Generic.0208
Key:
|----1----||----2-----||-3--||4||----5----||-----------6-----------|
GO:0009941 GO:0009536 TAIR D SF:575119 chloroplast envelope
(obs)
1. GO ID number
2. GO-slim term(s) that new term was added under or "obs" if the term is obsolete.
Terms with more than one GO-slim parent have further parents listed underneath the first parent.
3. Database that added term
4. indicates the existence of a definition for the term
5. the sourceforge request ID the term was added in response to
6. term name
Columns are tab-delimited and can be imported into Excel for ease of reading.
New terms in component ontology (11 new terms)
GO:0030897 GO:0005623 MAH D 856858 HOPS complex
GO:0005773
GO:0043073 GO:0005634 JL D 695398 germ cell nucleus
GO:0043074 GO:0005634 JL D 695398 microsporocyte nucleus
GO:0043075 GO:0005634 JL D 695398 pollen germ cell nucleus
GO:0043076 GO:0005634 JL D 695398 megasporocyte nucleus
GO:0043078 GO:0005634 JL D 695398 polar nucleus
GO:0043079 GO:0005634 JL D 695398 antipodal cell nucleus
GO:0043080 GO:0005634 JL D 695398 female germ cell nucleus (sensu Animalia)
GO:0043081 GO:0005634 JL D 695398 male germ cell nucleus (sensu Animalia)
GO:0043082 GO:0005634 JL D 695398 egg cell nucleus (sensu Viridiplantae)
GO:0043083 GO:0005578 JL D synaptic cleft
Term name changes in component ontology
GO:0001673: male germ-cell nucleus --> male germ cell nucleus
GO:0001674: female germ-cell nucleus --> female germ cell nucleus
GO:0019910: pyruvate dehydrogenase (lipoamide) phosphatase (sensu Eukarya) --> pyruvate dehydrogenase (lipoamide) phosphatase complex (sensu Eukarya)
GO:0045202: synaptic junction --> synapse
GO:0045249: pyruvate dehydrogenase (lipoamide) phosphatase (sensu Bacteria) --> pyruvate dehydrogenase (lipoamide) phosphatase complex (sensu Bacteria)
Term movements in component ontology:
Terms movements under GO Slim term 'cellular_component ; GO:0005575'
- GO:0008435, anticoagulant activity
- GO:0016172, antifreeze activity
- GO:0016173, ice nucleation inhibitor activity
New terms in function ontology (13 new terms)
GO:0030898 GO:0003824 MAH D 801353 actin dependent ATPase activity
GO:0030899 GO:0003824 MAH D 801353 calcium dependent ATPase activity
GO:0050800 GO:0003824 AI D 870909 hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement
GO:0050809 GO:0005488 AI D 872416 diazepam binding
GO:0050811 GO:0005102 AI D GABA receptor binding
GO:0050815 GO:0005515 AI D 873732 phosphoserine binding
GO:0050816 GO:0005515 AI D 873732 phosphothreonine binding
GO:0050824 GO:0005488 AI D 873051 water binding
GO:0050825 GO:0005488 AI D 873051 ice binding
GO:0050827 GO:0005102 AI D 873136 toxin receptor binding
GO:0050833 GO:0005215 AI D 861039 pyruvate transporter activity
GO:0050839 GO:0005515 AI D 881997 cell adhesion molecule binding
GO:0050840 GO:0005488 AI D 881997 extracellular matrix binding
New obsoletions in function ontology
GO:0000211, protein degradation tagging activity: represents a biological process and a molecular function.
GO:0000258, isoleucine/valine:sodium symporter activity: represents a multifunctional gene product.
GO:0003683, lamin/chromatin binding: represents two functions.
GO:0003793, defense/immunity protein activity: refers to involvement in a biological process.
GO:0003794, acute-phase response protein activity: refers to involvement in a biological process.
GO:0003795, antimicrobial peptide activity: describes involvement in a process and not a function.
GO:0003797, antibacterial peptide activity: describes involvement in a process and not a function.
GO:0003798, male-specific antibacterial peptide activity: describes involvement in a process and not a function.
GO:0003799, antifungal peptide activity: describes involvement in a process and not a function.
GO:0003800, antiviral response protein activity: refers to involvement in a biological process.
GO:0003801, blood coagulation factor activity: refers to involvement in a biological process.
GO:0003811, complement activity: refers to involvement in a biological process.
GO:0004895, cell adhesion receptor activity: represents a gene product.
GO:0005194, cell adhesion molecule activity: represents a gene product.
GO:0005301, valine/tyrosine/tryptophan permease activity: represents a multifunctional gene product.
GO:0005311, sodium:dicarboxylate/tricarboxylate symporter activity: represents a multifunctional gene product.
GO:0008014, calcium-dependent cell adhesion molecule activity: represents a gene product.
GO:0008025, diazepam binding inhibitor activity: represents a multifunctional gene product.
GO:0008189, apoptosis inhibitor activity: represents involvement in a biological process.
GO:0008224, Gram-positive antibacterial peptide activity: describes involvement in a process and not a function.
GO:0008225, Gram-negative antibacterial peptide activity: describes involvement in a process and not a function.
GO:0008435, anticoagulant activity: represents a biological process.
GO:0008638, protein tagging activity: represents a biological process and a molecular function.
GO:0015070, toxin activity: represents a classification of molecules and not a molecular function.
GO:0015316, nitrite/nitrate porter activity: represents a multifunctional gene product.
GO:0015331, asparagine/glutamine permease activity: represents a multifunctional gene product.
GO:0015332, leucine/valine/isoleucine permease activity: represents a multifunctional gene product.
GO:0015356, monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity: represents a multifunctional gene product.
GO:0015358, amino acid/choline transporter activity: represents a multifunctional gene product.
GO:0015363, dicarboxylate (succinate/fumarate/malate) antiporter activity: represents a multifunctional gene product.
GO:0015372, glutamate/aspartate:sodium symporter activity: represents a multifunctional gene product.
GO:0015376, betaine/GABA:sodium symporter activity: represents a multifunctional gene product.
GO:0015393, uracil/uridine permease activity: represents a multifunctional gene product.
GO:0015500, threonine/serine:sodium symporter activity: represents a multifunctional gene product.
GO:0015521, bicyclomycin/sulfathiazole:hydrogen antiporter activity: represents a multifunctional gene product.
GO:0015534, proline/glycine/betaine:hydrogen/sodium symporter activity: represents a multifunctional gene product.
GO:0015560, L-idonate/D-gluconate:hydrogen symporter activity: represents a multifunctional gene product.
GO:0015613, galactose/glucose (methylgalactoside) porter activity: represents a multifunctional gene product.
GO:0016172, antifreeze activity: This term was obsoleted because it refers to a biological process.
GO:0016173, ice nucleation inhibitor activity: This term was obsoleted because it refers to a biological process.
GO:0016329, apoptosis regulator activity: represents involvement in a biological process.
GO:0016347, calcium-independent cell adhesion molecule activity: represents a gene product.
GO:0016506, apoptosis activator activity: represents involvement in a biological process.
GO:0017028, protein stabilization activity: represents a biological process.
GO:0017030, beta-galactosidase stabilization activity: represents a biological process.
GO:0017149, protein biosynthesis inhibitor activity: represents involvement in a biological process.
GO:0019039, viral-cell fusion molecule activity: represents a gene product.
GO:0019214, surfactant activity: represents involvement in a process.
GO:0019833, ice nucleation activity: represents a biological process.
GO:0030009, complement factor H activity: represents a gene product.
GO:0030022, adhesive extracellular matrix constituent: does not represent a molecular function.
GO:0042064, cell adhesion receptor regulator activity: represents a gene product.
GO:0042072, cell adhesion receptor inhibitor activity: represents a gene product.
GO:0042280, cell surface antigen activity, host-interacting: describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.
GO:0045310, phosphoserine/phosphothreonine binding: represents two functions.
GO:0048191, peptide stabilization activity: represents a biological process.
GO:0048192, peptide antigen stabilization activity: represents a biological process.
Term name changes in function ontology
GO:0000210: NAD diphosphatase activity --> NAD+ diphosphatase activity
GO:0003713: transcription co-activator activity --> transcription coactivator activity
GO:0003714: transcription co-repressor activity --> transcription corepressor activity
GO:0003802: blood coagulation factor VII activity --> coagulation factor VIIa activity
GO:0003803: blood coagulation factor IX activity --> coagulation factor IXa activity
GO:0003804: blood coagulation factor X activity --> coagulation factor Xa activity
GO:0003805: blood coagulation factor XI activity --> coagulation factor XIa activity
GO:0003806: blood coagulation factor XII activity --> coagulation factor XIIa activity
GO:0003863: 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) activity --> 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity
GO:0003875: ADP-ribosylarginine hydrolase activity --> ADPribosylarginine hydrolase activity
GO:0003911: DNA ligase (NAD) activity --> DNA ligase (NAD+) activity
GO:0003918: DNA topoisomerase type II activity --> DNA topoisomerase (ATP-hydrolyzing) activity
GO:0003950: NAD ADP-ribosyltransferase activity --> NAD+ ADP-ribosyltransferase activity
GO:0003951: NAD kinase activity --> NAD+ kinase activity
GO:0003952: NAD synthase (glutamine-hydrolyzing) activity --> NAD+ synthase (glutamine-hydrolyzing) activity
GO:0003953: NAD nucleosidase activity --> NAD+ nucleosidase activity
GO:0003956: NAD(P)-arginine ADP-ribosyltransferase activity --> NAD(P)+-arginine ADP-ribosyltransferase activity
GO:0003957: NAD(P) transhydrogenase (B-specific) activity --> NAD(P)+ transhydrogenase (B-specific) activity
GO:0003958: NADPH-ferrihemoprotein reductase activity --> NADPH-hemoprotein reductase activity
GO:0004030: aldehyde dehydrogenase [NAD(P)] activity --> aldehyde dehydrogenase [NAD(P)+] activity
GO:0004148: dihydrolipoamide dehydrogenase activity --> dihydrolipoyl dehydrogenase activity
GO:0004149: dihydrolipoamide S-succinyltransferase activity --> dihydrolipoyllysine-residue succinyltransferase activity
GO:0004159: dihydrouracil dehydrogenase (NAD) activity --> dihydrouracil dehydrogenase (NAD+) activity
GO:0004251: Xaa-Pro dipeptidase activity --> X-Pro dipeptidase activity
GO:0004324: ferredoxin-NADP reductase activity --> ferredoxin-NADP+ reductase activity
GO:0004353: glutamate dehydrogenase [NAD(P)] activity --> glutamate dehydrogenase [NAD(P)+] activity
GO:0004354: glutamate dehydrogenase (NADP) activity --> glutamate dehydrogenase (NADP+) activity
GO:0004355: glutamate synthase (NADPH) activity --> glutamate synthase (NADPH+) activity
GO:0004367: glycerol-3-phosphate dehydrogenase (NAD) activity --> glycerol-3-phosphate dehydrogenase (NAD+) activity
GO:0004382: guanosine diphosphatase activity --> guanosine-diphosphatase activity
GO:0004449: isocitrate dehydrogenase (NAD) activity --> isocitrate dehydrogenase (NAD+) activity
GO:0004450: isocitrate dehydrogenase (NADP) activity --> isocitrate dehydrogenase (NADP+) activity
GO:0004473: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP) activity --> malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity
GO:0004487: methylenetetrahydrofolate dehydrogenase (NAD) activity --> methylenetetrahydrofolate dehydrogenase (NAD+) activity
GO:0004488: methylenetetrahydrofolate dehydrogenase (NADP) activity --> methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0004579: dolichyl-diphosphooligosaccharide-protein glycosyltransferase activity --> dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0004591: oxoglutarate dehydrogenase (lipoamide) activity --> oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0004665: prephenate dehydrogenase (NADP) activity --> prephenate dehydrogenase (NADP+) activity
GO:0004721: protein phosphatase activity --> phosphoprotein phosphatase activity
GO:0004725: protein tyrosine phosphatase activity --> protein-tyrosine-phosphatase activity
GO:0004739: pyruvate dehydrogenase (lipoamide) activity --> pyruvate dehydrogenase (acetyl-transferring) activity
GO:0004742: dihydrolipoamide S-acetyltransferase activity --> dihydrolipoyllysine-residue acetyltransferase activity
GO:0004754: saccharopine dehydrogenase (NAD, L-lysine-forming) activity --> saccharopine dehydrogenase (NAD+, L-lysine-forming) activity
GO:0004755: saccharopine dehydrogenase (NADP, L-glutamate-forming) activity --> saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity
GO:0004791: thioredoxin disulfide reductase activity --> thioredoxin-disulfide reductase activity
GO:0004800: thyroxine deiodinase activity --> thyroxine 5'-deiodinase activity
GO:0004805: trehalose phosphatase activity --> trehalose-phosphatase activity
GO:0004867: serine protease inhibitor activity --> serine-type endopeptidase inhibitor activity
GO:0005024: transforming growth factor-beta receptor activity --> transforming growth factor beta receptor activity
GO:0005025: type I transforming growth factor-beta receptor activity --> type I transforming growth factor beta receptor activity
GO:0005026: type II transforming growth factor-beta receptor activity --> type II transforming growth factor beta receptor activity
GO:0005032: tumor necrosis factor receptor cell differentiation, type I --> tumor necrosis factor receptor, type I
GO:0005072: TGFbeta receptor, cytoplasmic mediator activity --> transforming growth factor beta receptor, cytoplasmic mediator activity
GO:0005160: transforming growth factor-beta receptor binding --> transforming growth factor beta receptor binding
GO:0008025: diazepam-binding inhibitor activity --> diazepam binding inhibitor activity
GO:0008106: alcohol dehydrogenase (NADP) activity --> alcohol dehydrogenase (NADP+) activity
GO:0008185: transforming growth factor-alpha receptor binding --> transforming growth factor alpha receptor binding
GO:0008451: Xaa-Pro aminopeptidase activity --> X-Pro aminopeptidase activity
GO:0008549: dynamine GTPase activity --> dynamin GTPase activity
GO:0008675: 2-dehydro-3-deoxyphosphogluconate aldolase activity --> 2-dehydro-3-deoxy-phosphogluconate aldolase activity
GO:0008750: NAD(P) transhydrogenase (AB-specific) activity --> NAD(P)+ transhydrogenase (AB-specific) activity
GO:0008769: Xaa-His dipeptidase activity --> X-His dipeptidase activity
GO:0008772: [isocitrate dehydrogenase (NADP)] kinase activity --> [isocitrate dehydrogenase (NADP+)] kinase activity
GO:0008821: crossover junction endoribonuclease activity --> crossover junction endodeoxyribonuclease activity
GO:0008860: ferredoxin-NAD reductase activity --> ferredoxin-NAD+ reductase activity
GO:0008876: glucose dehydrogenase (pyrroloquinoline-quinone) activity --> quinoprotein glucose dehydrogenase activity
GO:0008886: glyceraldehyde-3-phosphate dehydrogenase (NADP) activity --> glyceraldehyde-3-phosphate dehydrogenase (NADP+) activity
GO:0009013: succinate-semialdehyde dehydrogenase [NAD(P)] activity --> succinate-semialdehyde dehydrogenase [NAD(P)+] activity
GO:0009035: type I site-specific deoxyribonuclease activity --> type 1 site-specific deoxyribonuclease activity
GO:0015425: nonpolar-amino acid-transporting ATPase activity --> nonpolar-amino-acid-transporting ATPase activity
GO:0016174: NADPH oxidase activity --> NAD(P)H oxidase activity
GO:0016404: 15-hydroxyprostaglandin dehydrogenase (NAD) activity --> 15-hydroxyprostaglandin dehydrogenase (NAD+) activity
GO:0017088: Xaa-Pro dipeptidyl-peptidase activity --> X-Pro dipeptidyl-peptidase activity
GO:0017110: nucleoside diphosphatase activity --> nucleoside-diphosphatase activity
GO:0017111: nucleoside triphosphatase activity --> nucleoside-triphosphatase activity
GO:0017113: dihydropyrimidine dehydrogenase (NADP) activity --> dihydropyrimidine dehydrogenase (NADP+) activity
GO:0018455: alcohol dehydrogenase [NAD(P)] activity --> alcohol dehydrogenase [NAD(P)+] activity
GO:0018477: benzaldehyde dehydrogenase (NADP) activity --> benzaldehyde dehydrogenase (NADP+) activity
GO:0018479: benzaldehyde dehydrogenase (NAD) activity --> benzaldehyde dehydrogenase (NAD+) activity
GO:0018489: vanillate demethylase activity --> vanillate monooxygenase activity
GO:0018492: carbon-monoxide dehydrogenase activity --> carbon-monoxide dehydrogenase (acceptor) activity
GO:0018674: (-)-limonene 3-monooxygenase activity --> (S)-limonene 3-monooxygenase activity
GO:0018675: (-)-limonene 6-monooxygenase activity --> (S)-limonene 6-monooxygenase activity
GO:0018676: (-)-limonene 7-monooxygenase activity --> (S)-limonene 7-monooxygenase activity
GO:0018784: 2-haloacid dehalogenase activity --> (S)-2-haloacid dehalogenase activity
GO:0018833: DDT dehydrochlorinase activity --> DDT-dehydrochlorinase activity
GO:0019727: mevaldate reductase (NAD) activity --> mevaldate reductase (NAD+) activity
GO:0019828: aspartic protease inhibitor activity --> aspartic-type endopeptidase inhibitor activity
GO:0030306: ARF binding --> ADP-ribosylation factor binding
GO:0030374: ligand-dependent nuclear receptor transcription co-activator activity --> ligand-dependent nuclear receptor transcription coactivator activity
GO:0030375: thyroid hormone receptor co-activator activity --> thyroid hormone receptor coactivator activity
GO:0030586: [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing) activity --> [methionine synthase] reductase activity
GO:0030616: TGFbeta receptor, common-partner cytoplasmic mediator activity --> transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0030617: TGFbeta receptor, inhibitory cytoplasmic mediator activity --> transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
GO:0030618: TGFbeta receptor, pathway-specific cytoplasmic mediator activity --> transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0030701: NAD-dinitrogen-reductase ADP-D-ribosyltransferase activity --> NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity
GO:0042057: transforming growth factor-beta receptor anchoring activity --> transforming growth factor beta receptor anchoring activity
GO:0042980: CFTR binding --> cystic fibrosis transmembrane conductance regulator binding
GO:0045290: D-arabinose 1-dehydrogenase [NAD(P)] activity --> D-arabinose 1-dehydrogenase [NAD(P)+] activity
GO:0046406: magnesium-protoporphyrin O-methyltransferase activity --> magnesium protoporphyrin IX methyltransferase activity
GO:0046554: malate dehydrogenase (NADP) activity --> malate dehydrogenase (NADP+) activity
GO:0047007: 21-hydroxysteroid dehydrogenase (NAD) activity --> 21-hydroxysteroid dehydrogenase (NAD+) activity
GO:0047008: 21-hydroxysteroid dehydrogenase (NADP) activity --> 21-hydroxysteroid dehydrogenase (NADP+) activity
GO:0047014: glycerol-3-phosphate 1-dehydrogenase (NADP) activity --> glycerol-3-phosphate 1-dehydrogenase (NADP+) activity
GO:0047020: 15-hydroxyprostaglandin-D dehydrogenase (NADP) activity --> 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
GO:0047021: 15-hydroxyprostaglandin dehydrogenase (NADP) activity --> 15-hydroxyprostaglandin dehydrogenase (NADP+) activity
GO:0047022: 7-beta-hydroxysteroid dehydrogenase (NADP) activity --> 7-beta-hydroxysteroid dehydrogenase (NADP+) activity
GO:0047033: 15-hydroxyprostaglandin-I dehydrogenase (NADP) activity --> 15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity
GO:0047035: 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD) activity --> 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
GO:0047045: testosterone 17-beta-dehydrogenase (NADP) activity --> testosterone 17-beta-dehydrogenase (NADP+) activity
GO:0047081: 3-hydroxy-3-methylpyridinecarboxylate dioxygenase activity --> 3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity
GO:0047100: glyceraldehyde-3-phosphate dehydrogenase (NADP) (phosphorylating) activity --> glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity
GO:0047108: (R)-3-hydroxyacid ester dehydrogenase activity --> (R)-3-hydroxyacid-ester dehydrogenase activity
GO:0047109: (S)-3-hydroxyacid ester dehydrogenase activity --> (S)-3-hydroxyacid-ester dehydrogenase activity
GO:0047130: saccharopine dehydrogenase (NADP, L-lysine-forming) activity --> saccharopine dehydrogenase (NADP+, L-lysine-forming) activity
GO:0047131: saccharopine dehydrogenase (NAD, L-glutamate-forming) activity --> saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity
GO:0047154: methylmalonyl-CoA carboxyltransferase activity --> methylmalonyl-CoA carboxytransferase activity
GO:0047193: CDP-acylglycerol O-arachidonyltransferase activity --> CDP-acylglycerol O-arachidonoyltransferase activity
GO:0047216: inositol 1-alpha-galactosyltransferase activity --> inositol 3-alpha-galactosyltransferase activity
GO:0047286: NAD-diphthamide ADP-ribosyltransferase activity --> NAD+-diphthamide ADP-ribosyltransferase activity
GO:0047290: (alpha-N-acetylneuraminyl-2,3-alpha-galactosyl-1,3)-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity --> alpha-N-acetylneuraminyl-2,3-alpha-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity
GO:0047354: sphingosine choline phosphotransferase activity --> sphingosine cholinephosphotransferase activity
GO:0047453: ATP-dependent H4NAD(P)OH dehydratase activity --> ATP-dependent NAD(P)H-hydrate dehydratase activity
GO:0047552: 2-oxoaldehyde dehydrogenase (NADP) activity --> 2-oxoaldehyde dehydrogenase (NADP+) activity
GO:0047616: acyl-CoA dehydrogenase (NADP) activity --> acyl-CoA dehydrogenase (NADP+) activity
GO:0047681: aryl-alcohol dehydrogenase (NADP) activity --> aryl-alcohol dehydrogenase (NADP+) activity
GO:0047683: aryl-aldehyde dehydrogenase (NADP) activity --> aryl-aldehyde dehydrogenase (NADP+) activity
GO:0047837: D-xylose 1-dehydrogenase (NADP) activity --> D-xylose 1-dehydrogenase (NADP+) activity
GO:0047899: formate dehydrogenase (NADP) activity --> formate dehydrogenase (NADP+) activity
GO:0047903: fructose 5-dehydrogenase (NADP) activity --> fructose 5-dehydrogenase (NADP+) activity
GO:0047910: galactose 1-dehydrogenase (NADP) activity --> galactose 1-dehydrogenase (NADP+) activity
GO:0047934: glucose 1-dehydrogenase (NAD) activity --> glucose 1-dehydrogenase (NAD+) activity
GO:0047935: glucose 1-dehydrogenase (NADP) activity --> glucose 1-dehydrogenase (NADP+) activity
GO:0047952: glycerol-3-phosphate dehydrogenase [NAD(P)] activity --> glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GO:0047953: glycerol 2-dehydrogenase (NADP) activity --> glycerol 2-dehydrogenase (NADP+) activity
GO:0047956: glycerol dehydrogenase (NADP) activity --> glycerol dehydrogenase (NADP+) activity
GO:0050009: isopropanol dehydrogenase (NADP) activity --> isopropanol dehydrogenase (NADP+) activity
GO:0050085: mannitol 2-dehydrogenase (NADP) activity --> mannitol 2-dehydrogenase (NADP+) activity
GO:0050135: NAD(P) nucleosidase activity --> NAD(P)+ nucleosidase activity
GO:0050164: oxoglutarate dehydrogenase (NADP) activity --> oxoglutarate dehydrogenase (NADP+) activity
GO:0050243: pyruvate dehydrogenase (NADP) activity --> pyruvate dehydrogenase (NADP+) activity
GO:0050259: ribose 1-dehydrogenase (NADP) activity --> ribose 1-dehydrogenase (NADP+) activity
GO:0050287: sorbose 5-dehydrogenase (NADP) activity --> sorbose 5-dehydrogenase (NADP+) activity
GO:0050343: trans-2-enoyl-CoA reductase (NAD) activity --> trans-2-enoyl-CoA reductase (NAD+) activity
GO:0050431: TGFbeta binding --> transforming growth factor beta binding
GO:0050492: glycerol-1-phosphate dehydrogenase [NAD(P)] activity --> glycerol-1-phosphate dehydrogenase [NAD(P)+] activity
GO:0050552: (-)-(4S)-limonene synthase activity --> (4S)-limonene synthase activity
GO:0050583: hydrogen dehydrogenase (NADP) activity --> hydrogen dehydrogenase (NADP+) activity
New definitions for function ontology terms (66 new definitions)
GO:0003683, lamin/chromatin binding
GO:0003794, acute-phase response protein activity
GO:0003800, antiviral response protein activity
GO:0003801, blood coagulation factor activity
GO:0004859, phospholipase inhibitor activity
GO:0004860, protein kinase inhibitor activity
GO:0004864, protein phosphatase inhibitor activity
GO:0004867, serine-type endopeptidase inhibitor activity
GO:0005051, peroxisome targeting signal receptor activity
GO:0005301, valine/tyrosine/tryptophan permease activity
GO:0005518, collagen binding
GO:0005520, insulin-like growth factor binding
GO:0005522, profilin binding
GO:0005523, tropomyosin binding
GO:0008022, protein C-terminus binding
GO:0008025, diazepam binding inhibitor activity
GO:0008139, nuclear localization sequence binding
GO:0008160, protein tyrosine phosphatase activator activity
GO:0008190, eukaryotic initiation factor 4E binding
GO:0008191, metalloendopeptidase inhibitor activity
GO:0008426, protein kinase C inhibitor activity
GO:0008428, ribonuclease inhibitor activity
GO:0008439, monophenol monooxygenase activator activity
GO:0015316, nitrite/nitrate porter activity
GO:0015332, leucine/valine/isoleucine permease activity
GO:0015356, monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity
GO:0015358, amino acid/choline transporter activity
GO:0015363, dicarboxylate (succinate/fumarate/malate) antiporter activity
GO:0015393, uracil/uridine permease activity
GO:0015613, galactose/glucose (methylgalactoside) porter activity
GO:0016004, phospholipase activator activity
GO:0016005, phospholipase A2 activator activity
GO:0016030, metarhodopsin binding
GO:0016173, ice nucleation inhibitor activity
GO:0016176, superoxide-generating NADPH oxidase activator activity
GO:0016230, sphingomyelin phosphodiesterase activator activity
GO:0016347, calcium-independent cell adhesion molecule activity
GO:0016483, tryptophan hydroxylase activator activity
GO:0016504, protease activator activity
GO:0017030, beta-galactosidase stabilization activity
GO:0017033, DNA topoisomerase I binding
GO:0017149, protein biosynthesis inhibitor activity
GO:0017166, vinculin binding
GO:0019039, viral-cell fusion molecule activity
GO:0019207, kinase regulator activity
GO:0019208, phosphatase regulator activity
GO:0019209, kinase activator activity
GO:0019211, phosphatase activator activity
GO:0019212, phosphatase inhibitor activity
GO:0019215, intermediate filament binding
GO:0019828, aspartic-type endopeptidase inhibitor activity
GO:0019834, phospholipase A2 inhibitor activity
GO:0019887, protein kinase regulator activity
GO:0019957, C-C chemokine binding
GO:0019958, C-X-C chemokine binding
GO:0019960, C-X3-C chemokine binding
GO:0030161, calpain inhibitor activity
GO:0030295, protein kinase activator activity
GO:0030296, protein tyrosine kinase activator activity
GO:0030304, trypsin inhibitor activity
GO:0030306, ADP-ribosylation factor binding
GO:0030415, carboxypeptidase A inhibitor activity
GO:0030544, Hsp70 protein binding
GO:0030742, GTP-dependent protein binding
GO:0042064, cell adhesion receptor regulator activity
GO:0042072, cell adhesion receptor inhibitor activity
Term movements in function ontology:
Terms movements under GO Slim term 'chromatin binding ; GO:0003682'
- GO:0003683, lamin/chromatin binding
Terms movements under GO Slim term 'defense/immunity protein activity ; GO:0003793'
- GO:0003793, defense/immunity protein activity
- GO:0003794, acute-phase response protein activity
- GO:0003795, antimicrobial peptide activity
- GO:0003796, lysozyme activity
- GO:0003797, antibacterial peptide activity
- GO:0003798, male-specific antibacterial peptide activity
- GO:0003799, antifungal peptide activity
- GO:0003800, antiviral response protein activity
- GO:0003801, blood coagulation factor activity
- GO:0003802, coagulation factor VIIa activity
- GO:0003803, coagulation factor IXa activity
- GO:0003804, coagulation factor Xa activity
- GO:0003805, coagulation factor XIa activity
- GO:0003806, coagulation factor XIIa activity
- GO:0003807, plasma kallikrein activity
- GO:0003808, protein C (activated) activity
- GO:0003809, thrombin activity
- GO:0003811, complement activity
- GO:0003812, alternative-complement-pathway C3/C5 convertase activity
- GO:0003813, classical-complement-pathway C3/C5 convertase activity
- GO:0003815, complement component C1r activity
- GO:0003816, complement component C1s activity
- GO:0003817, complement factor D activity
- GO:0003818, complement factor I activity
- GO:0003823, antigen binding
- GO:0008224, Gram-positive antibacterial peptide activity
- GO:0008225, Gram-negative antibacterial peptide activity
- GO:0015643, toxin binding
- GO:0019763, Fc receptor activity
- GO:0019764, high affinity Fc receptor activity
- GO:0019765, low affinity Fc receptor activity
- GO:0019766, IgA receptor activity
- GO:0019767, IgE receptor activity
- GO:0019768, high affinity IgE receptor activity
- GO:0019769, low affinity IgE receptor activity
- GO:0019770, IgG receptor activity
- GO:0019771, high affinity IgG receptor activity
- GO:0019772, low affinity IgG receptor activity
- GO:0030009, complement factor H activity
- GO:0030882, lipid antigen binding
- GO:0030883, endogenous lipid antigen binding
- GO:0030884, exogenous lipid antigen binding
- GO:0042071, leucokinin receptor activity
- GO:0042280, cell surface antigen activity, host-interacting
- GO:0042605, peptide antigen binding
- GO:0042606, endogenous peptide antigen binding
- GO:0042607, exogenous peptide antigen binding
Terms movements under GO Slim term 'catalytic activity ; GO:0003824'
- GO:0015613, galactose/glucose (methylgalactoside) porter activity
Terms movements under GO Slim term 'receptor activity ; GO:0004872'
- GO:0004895, cell adhesion receptor activity
Terms movements under GO Slim term 'cell adhesion molecule activity ; GO:0005194'
- GO:0004895, cell adhesion receptor activity
- GO:0005194, cell adhesion molecule activity
- GO:0008014, calcium-dependent cell adhesion molecule activity
- GO:0016347, calcium-independent cell adhesion molecule activity
- GO:0019039, viral-cell fusion molecule activity
- GO:0030022, adhesive extracellular matrix constituent
- GO:0042064, cell adhesion receptor regulator activity
- GO:0042072, cell adhesion receptor inhibitor activity
Terms movements under GO Slim term 'structural molecule activity ; GO:0005198'
- GO:0015070, toxin activity
- GO:0019214, surfactant activity
- GO:0030022, adhesive extracellular matrix constituent
Terms movements under GO Slim term 'transporter activity ; GO:0005215'
- GO:0000258, isoleucine/valine:sodium symporter activity
- GO:0005301, valine/tyrosine/tryptophan permease activity
- GO:0005311, sodium:dicarboxylate/tricarboxylate symporter activity
- GO:0015316, nitrite/nitrate porter activity
- GO:0015331, asparagine/glutamine permease activity
- GO:0015332, leucine/valine/isoleucine permease activity
- GO:0015356, monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity
- GO:0015358, amino acid/choline transporter activity
- GO:0015363, dicarboxylate (succinate/fumarate/malate) antiporter activity
- GO:0015372, glutamate/aspartate:sodium symporter activity
- GO:0015376, betaine/GABA:sodium symporter activity
- GO:0015393, uracil/uridine permease activity
- GO:0015500, threonine/serine:sodium symporter activity
- GO:0015521, bicyclomycin/sulfathiazole:hydrogen antiporter activity
- GO:0015534, proline/glycine/betaine:hydrogen/sodium symporter activity
- GO:0015560, L-idonate/D-gluconate:hydrogen symporter activity
- GO:0015613, galactose/glucose (methylgalactoside) porter activity
Terms movements under GO Slim term 'neurotransmitter transporter activity ; GO:0005326'
- GO:0015376, betaine/GABA:sodium symporter activity
Terms movements under GO Slim term 'protein binding ; GO:0005515'
- GO:0045310, phosphoserine/phosphothreonine binding
Terms movements under GO Slim term 'protein tagging activity ; GO:0008638'
- GO:0000211, protein degradation tagging activity
- GO:0008638, protein tagging activity
Terms movements under GO Slim term 'apoptosis regulator activity ; GO:0016329'
- GO:0008189, apoptosis inhibitor activity
- GO:0008656, caspase activator activity
- GO:0016329, apoptosis regulator activity
- GO:0016505, apoptotic protease activator activity
- GO:0016506, apoptosis activator activity
- GO:0043027, caspase inhibitor activity
Terms movements under GO Slim term 'protein stabilization activity ; GO:0017028'
- GO:0017028, protein stabilization activity
- GO:0017030, beta-galactosidase stabilization activity
- GO:0048191, peptide stabilization activity
- GO:0048192, peptide antigen stabilization activity
Terms movements under GO Slim term 'enzyme regulator activity ; GO:0030234'
- GO:0008025, diazepam binding inhibitor activity
- GO:0017149, protein biosynthesis inhibitor activity
- GO:0019833, ice nucleation activity
New terms in process ontology (64 new terms)
GO:0001788 GO:0008219 MGI D antibody-dependent cellular cytotoxicity
GO:0001789 GO:0007165 MGI D G-protein signaling, coupled to S1P second messenger (sphingosine kinase activating)
GO:0030900 GO:0007275 MAH D forebrain development
GO:0030901 GO:0007275 MAH D midbrain development
GO:0030902 GO:0007275 MAH D hindbrain development
GO:0030903 GO:0007275 MAH D notochord development
GO:0043062 GO:0007582 JL D 857620 extracellular structure organization and biogenesis
GO:0043063 GO:0007582 JL D 857620 intercellular bridge organization and biogenesis
GO:0043064 GO:0007275 JL D 862264 flagellum organization and biogenesis
GO:0016043
GO:0043065 GO:0008219 JL D positive regulation of apoptosis
GO:0043066 GO:0008219 JL D negative regulation of apoptosis
GO:0043067 GO:0008219 JL D regulation of programmed cell death
GO:0043068 GO:0008219 JL D positive regulation of programmed cell death
GO:0043069 GO:0008219 JL D negative regulation of programmed cell death
GO:0043070 GO:0008219 JL D regulation of non-apoptotic programmed cell death
GO:0043071 GO:0008219 JL D positive regulation of non-apoptotic programmed cell death
GO:0043072 GO:0008219 JL D negative regulation of non-apoptotic programmed cell death
GO:0043077 GO:0008152 JL D 695398 initiation of acetate catabolism
GO:0009056
GO:0043084 GO:0007610 JL D penile erection
GO:0043085 GO:0008150 JL D positive regulation of enzyme activity
GO:0043086 GO:0008150 JL D negative regulation of enzyme activity
GO:0043087 GO:0008150 JL D regulation of GTPase activity
GO:0043088 GO:0008150 JL D regulation of Cdc42 GTPase activity
GO:0043089 GO:0008150 JL D positive regulation of Cdc42 GTPase activity
GO:0043090 GO:0006810 JL D 882073 amino acid import
GO:0043091 GO:0006810 JL D 882073 L-arginine import
GO:0043092 GO:0006810 JL D 882073 L-amino acid import
GO:0043093 GO:0008283 JL D 872001 binary fission
GO:0048276 GO:0007275 JIC D 871238 gastrulation (sensu Vertebrata)
GO:0048277 GO:0006810 JIC D non-exocytotic vesicle docking
GO:0048278 GO:0006810 JIC D vesicle docking
GO:0050798 GO:0007582 AI D activated T-cell proliferation
GO:0008283
GO:0009607
GO:0050799 GO:0008152 AI D 859003 cocaine biosynthesis
GO:0009058
GO:0050801 GO:0007582 AI D 869226 ion homeostasis
GO:0050802 GO:0007582 AI D 862348 circadian sleep/wake cycle, sleep
GO:0007610
GO:0050803 GO:0007267 AI D 862300 regulation of synapse structure and function
GO:0050804 GO:0007267 AI D 862300 regulation of synaptic transmission
GO:0050805 GO:0007267 AI D 862300 negative regulation of synaptic transmission
GO:0050806 GO:0007267 AI D 862300 positive regulation of synaptic transmission
GO:0050807 GO:0007267 AI D 862300 regulation of synapse structure
GO:0007582
GO:0050808 GO:0007582 AI D 862300 synapse organization and biogenesis
GO:0050810 GO:0006629 AI D regulation of steroid biosynthesis
GO:0008152
GO:0009058
GO:0050812 GO:0006629 AI D regulation of acyl-CoA biosynthesis
GO:0006731
GO:0008152
GO:0009058
GO:0050813 GO:0008152 AI D 875351 epothilone metabolism
GO:0019748
GO:0050814 GO:0008152 AI D 875351 epothilone biosynthesis
GO:0009058
GO:0019748
GO:0050817 GO:0007582 AI D coagulation
GO:0050818 GO:0007582 AI D regulation of coagulation
GO:0008150
GO:0050819 GO:0007582 AI D negative regulation of coagulation
GO:0008150
GO:0050820 GO:0007582 AI D positive regulation of coagulation
GO:0008150
GO:0050821 GO:0019538 AI D protein stabilization
GO:0050822 GO:0008152 AI D peptide stabilization
GO:0050823 GO:0008152 AI D peptide antigen stabilization
GO:0050826 GO:0006950 AI D 873051 response to freezing
GO:0009628
GO:0050828 GO:0007582 AI D 873136 regulation of liquid surface tension
GO:0050829 GO:0009607 AI D defense response to Gram-negative bacteria
GO:0050830 GO:0009607 AI D defense response to Gram-positive bacteria
GO:0050831 GO:0009607 AI D male-specific defense response to bacteria
GO:0050832 GO:0009607 AI D defense response to fungi
GO:0050834 GO:0006464 AI D molybdenum incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinuncleotide
GO:0050835 GO:0006464 AI D iron incorporation into iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide
GO:0050836 GO:0006464 AI D iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide
GO:0050837 GO:0006464 AI D peptide cross-linking via L-cysteinyl-L-selenocysteine
GO:0050838 GO:0006464 AI D peptidyl-5-hydroxy-L-lysine tri-methylation
GO:0050841 GO:0006464 AI D peptidyl-N6,N6,N6-trimethyl-lysine hydroxylation to peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine
New obsoletions in process ontology
GO:0006943, chemi-mechanical coupling: its meaning is vague, and it does not fit with other terms in GO.
GO:0007273, regulation of synapse: the term string made no sense.
GO:0046908, negative regulation of crystal formation: a more appropriate term was created.
Term name changes in process ontology
GO:0000183: chromatin silencing at ribosomal DNA (rDNA) --> chromatin silencing at ribosomal DNA
GO:0000301: retrograde (vesicle recycling within Golgi) transport --> retrograde transport, vesicle recycling within Golgi
GO:0001507: acetylcholine breakdown in the synaptic cleft --> acetylcholine breakdown in synaptic cleft
GO:0006890: retrograde (Golgi to ER) transport --> retrograde transport, Golgi to ER
GO:0006900: nonselective vesicle budding --> vesicle budding
GO:0006901: nonselective vesicle coating --> vesicle coating
GO:0006903: nonselective vesicle targeting --> vesicle targeting
GO:0006904: nonselective vesicle docking --> vesicle docking during the process of exocytosis
GO:0006906: nonselective vesicle fusion --> vesicle fusion
GO:0007038: endocytosed protein transport to the vacuole --> endocytosed protein transport to vacuole
GO:0007179: TGFbeta receptor signaling pathway --> transforming growth factor beta receptor signaling pathway
GO:0007180: TGFbeta ligand binding to type II receptor --> transforming growth factor beta ligand binding to type II receptor
GO:0007181: TGFbeta receptor complex assembly --> transforming growth factor beta receptor complex assembly
GO:0008228: opsinization --> opsonization
GO:0008259: TGFbeta ligand binding to type I receptor --> transforming growth factor beta ligand binding to type I receptor
GO:0008634: negative regulation of survival gene products --> negative regulation of survival gene product activity
GO:0009296: flagella biogenesis --> flagellum biogenesis
GO:0009814: response to pathogen (incompatible interaction) --> defense response to pathogen, incompatible interaction
GO:0009816: response to pathogenic bacteria (incompatible interaction) --> defense response to pathogenic bacteria, incompatible interaction
GO:0009817: response to pathogenic fungi (incompatible interaction) --> defense response to pathogenic fungi, incompatible interaction
GO:0009818: response to pathogenic protozoa (incompatible interaction) --> defense response to pathogenic protozoa, incompatible interaction
GO:0009862: salicylic acid mediated signaling pathway (systemic acquired resistance) --> systemic acquired resistance, salicylic acid mediated signaling pathway
GO:0009864: jasmonic acid mediated signaling pathway (induced systemic resistance) --> induced systemic resistance, jasmonic acid mediated signaling pathway
GO:0009866: ethylene mediated signaling pathway (induced systemic resistance) --> induced systemic resistance, ethylene mediated signaling pathway
GO:0009868: jasmonic acid mediated signaling pathway (jasmonic acid/ethylene dependent systemic resistance) --> jasmonic acid/ethylene dependent systemic resistance, jasmonic acid mediated signaling pathway
GO:0009871: ethylene mediated signaling pathway (jasmonic acid/ethylene dependent systemic resistance) --> jasmonic acid/ethylene dependent systemic resistance, ethylene mediated signaling pathway
GO:0009944: polarity specification of the adaxial/abaxial axis --> polarity specification of adaxial/abaxial axis
GO:0009949: polarity specification of the anterior/posterior axis --> polarity specification of anterior/posterior axis
GO:0009951: polarity specification of the dorsal/ventral axis --> polarity specification of dorsal/ventral axis
GO:0010085: polarity specification of the proximal/distal axis --> polarity specification of proximal/distal axis
GO:0015628: type II protein (Sec) secretion system --> type II protein secretion system
GO:0015969: guanosine tetraphosphate (5'-ppGpp-3') metabolism --> guanosine tetraphosphate metabolism
GO:0015970: guanosine tetraphosphate (5'-ppGpp-3') biosynthesis --> guanosine tetraphosphate biosynthesis
GO:0015971: guanosine tetraphosphate (5'-ppGpp-3') catabolism --> guanosine tetraphosphate catabolism
GO:0015972: guanosine pentaphosphate (5'-pppGpp-3') metabolism --> guanosine pentaphosphate metabolism
GO:0015973: guanosine pentaphosphate (5'-pppGpp-3') biosynthesis --> guanosine pentaphosphate biosynthesis
GO:0015974: guanosine pentaphosphate (5'-pppGpp-3') catabolism --> guanosine pentaphosphate catabolism
GO:0015985: energy coupled proton transport, down the electrochemical gradient --> energy coupled proton transport, down electrochemical gradient
GO:0015988: energy coupled proton transport, against the electrochemical gradient --> energy coupled proton transport, against electrochemical gradient
GO:0016320: ER fusion --> endoplasmic reticulum membrane fusion
GO:0017015: regulation of TGFbeta receptor signaling pathway --> regulation of transforming growth factor beta receptor signaling pathway
GO:0019052: viral inhibition of intracellular antiviral response --> negative regulation of intracellular antiviral response by virus
GO:0019053: viral inhibition of extracellular antiviral response --> negative regulation of extracellular antiviral response by virus
GO:0019379: sulfate assimilation, phosphoadenylyl sulfate reduction by a phosphoadenylyl-sulfate reductase (thioredoxin) --> sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)
GO:0030032: lamellipodium formation --> lamellipodium biogenesis
GO:0030033: microvillus assembly --> microvillus biogenesis
GO:0030035: microspike formation --> microspike biogenesis
GO:0030092: regulation of flagella biosynthesis --> regulation of flagellum biogenesis
GO:0030278: regulation of bone formation --> regulation of ossification
GO:0030279: negative regulation of bone formation --> negative regulation of ossification
GO:0030503: regulation of redox homeostasis --> regulation of cell redox homeostasis
GO:0030511: positive regulation of TGFbeta receptor signaling pathway --> positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030512: negative regulation of TGFbeta receptor signaling pathway --> negative regulation of transforming growth factor beta receptor signaling pathway
GO:0042103: positive regulation of resting T-cell proliferation --> positive regulation of T-cell homeostatic proliferation
GO:0042144: vacuole fusion (non-autophagic) --> vacuole fusion, non-autophagic
GO:0042145: homotypic vacuole fusion (non-autophagic) --> homotypic vacuole fusion, non-autophagic
GO:0042146: heterotypic vacuole fusion (non-autophagic) --> heterotypic vacuole fusion, non-autophagic
GO:0042147: retrograde (endosome to Golgi) transport --> retrograde transport, endosome to Golgi
GO:0042320: regulation of REM sleep --> regulation of circadian sleep/wake cycle, REM sleep
GO:0042321: negative regulation of sleep --> negative regulation of circadian sleep/wake cycle, sleep
GO:0042322: negative regulation of REM sleep --> negative regulation of circadian sleep/wake cycle, REM sleep
GO:0042323: negative regulation of non-REM sleep --> negative regulation of circadian sleep/wake cycle, non-REM sleep
GO:0042348: NF-kappaB protein-nucleus import --> NF-kappaB-nucleus import
GO:0045018: retrograde transport from the vacuole --> retrograde transport, vacuole to Golgi
GO:0045146: acetate induction of acetate catabolism --> initiation of acetate catabolism by acetate
GO:0045147: regulation of acetate induction of acetate catabolism --> regulation of initiation of acetate catabolism by acetate
GO:0045187: regulation of sleep --> regulation of circadian sleep/wake cycle, sleep
GO:0045188: regulation of non-REM sleep --> regulation of circadian sleep/wake cycle, non-REM sleep
GO:0045718: negative regulation of flagella biosynthesis --> negative regulation of flagellum biogenesis
GO:0045724: positive regulation of flagella biosynthesis --> positive regulation of flagellum biogenesis
GO:0045755: negative regulation of acetate induction of acetate catabolism --> negative regulation of initiation of acetate catabolism by acetate
GO:0045756: positive regulation of acetate induction of acetate catabolism --> positive regulation of initiation of acetate catabolism by acetate
GO:0045778: positive regulation of bone formation --> positive regulation of ossification
GO:0045884: regulation of survival gene products --> regulation of survival gene product activity
GO:0045885: positive regulation of survival gene products --> positive regulation of survival gene product activity
GO:0045938: positive regulation of sleep --> positive regulation of circadian sleep/wake cycle, sleep
GO:0046005: positive regulation of REM sleep --> positive regulation of circadian sleep/wake cycle, REM sleep
GO:0046010: positive regulation of non-REM sleep --> positive regulation of circadian sleep/wake cycle, non-REM sleep
GO:0046013: regulation of resting T-cell proliferation --> regulation of T-cell homeostatic proliferation
GO:0046014: negative regulation of resting T-cell proliferation --> negative regulation of T-cell homeostatic proliferation
GO:0050689: negative regulation by host of antiviral response --> negative regulation of antiviral response by host
GO:0050690: viral regulation of antiviral response --> regulation of antiviral response by virus
GO:0050691: host regulation of antiviral response --> regulation of antiviral response by host
New definitions for process ontology terms (10 new definitions)
GO:0006900, vesicle budding
GO:0006901, vesicle coating
GO:0006903, vesicle targeting
GO:0006904, vesicle docking during the process of exocytosis
GO:0006906, vesicle fusion
GO:0007273, regulation of synapse
GO:0007416, synaptogenesis
GO:0008228, opsonization
GO:0016244, non-apoptotic programmed cell death
GO:0016320, endoplasmic reticulum membrane fusion
New term merges in process ontology
GO:0006899 has been merged into GO:0016192, vesicle-mediated transport
GO:0006902 has been merged into GO:0006900, vesicle budding
GO:0016193 has been merged into GO:0006897, endocytosis
GO:0016194 has been merged into GO:0006887, exocytosis
Term movements in process ontology:
Terms movements under GO Slim term 'chemi-mechanical coupling ; GO:0006943'
- GO:0006943, chemi-mechanical coupling
Terms movements under GO Slim term 'organelle organization and biogenesis ; GO:0006996'
- GO:0000042, protein-Golgi targeting
- GO:0006613, cotranslational membrane targeting
- GO:0006614, SRP-dependent cotranslational membrane targeting
- GO:0006615, SRP-dependent cotranslational membrane targeting, docking
- GO:0006616, SRP-dependent cotranslational membrane targeting, translocation
- GO:0006617, SRP-dependent cotranslational membrane targeting, signal sequence recognition
- GO:0006618, SRP-dependent cotranslational membrane targeting, signal sequence processing
- GO:0006619, SRP-independent cotranslational membrane targeting
- GO:0006620, posttranslational membrane targeting
- GO:0006621, protein-ER retention
- GO:0006622, protein-lysosome targeting
- GO:0006623, protein-vacuolar targeting
- GO:0006624, vacuolar protein processing/maturation
- GO:0006625, protein-peroxisome targeting
- GO:0016256, N-glycan processing to lysosome
- GO:0016558, peroxisome matrix protein import
- GO:0045036, protein-chloroplast targeting
- GO:0045037, chloroplast stroma protein import
- GO:0045038, chloroplast thylakoid protein import
- GO:0045046, peroxisome membrane protein import
- GO:0045047, protein-ER targeting
- GO:0045048, protein-ER insertion
- GO:0045049, ER insertion by N-terminal cleaved signal sequence
- GO:0045050, ER insertion by stop-transfer membrane-anchor sequence
- GO:0045051, ER insertion by internal uncleaved signal-anchor sequence
- GO:0045052, ER insertion by GPI attachment sequence
- GO:0045053, protein-Golgi retention
- GO:0045319, SRP-independent cotranslational membrane targeting, translocation
Terms movements under GO Slim term 'mitochondrion organization and biogenesis ; GO:0007005'
- GO:0006626, protein-mitochondrial targeting
- GO:0006627, mitochondrial processing
- GO:0030150, mitochondrial matrix protein import
- GO:0045041, mitochondrial intermembrane space protein import
- GO:0045042, conservative mitochondrial IMS protein import
- GO:0045043, non-conservative mitochondrial IMS protein import
- GO:0045044, direct mitochondrial IMS protein import
Terms movements under GO Slim term 'cell-cell signaling ; GO:0007267'
- GO:0007273, regulation of synapse
Terms movements under GO Slim term 'physiological process ; GO:0007582'
+ GO:0006873, cell ion homeostasis
+ GO:0006874, calcium ion homeostasis
+ GO:0006875, metal ion homeostasis
+ GO:0006876, cadmium ion homeostasis
+ GO:0006877, cobalt ion homeostasis
+ GO:0006878, copper ion homeostasis
+ GO:0006879, iron ion homeostasis
+ GO:0006880, intracellular iron ion storage
+ GO:0006881, extracellular iron ion storage
+ GO:0006882, zinc ion homeostasis
+ GO:0006883, sodium ion homeostasis
+ GO:0006885, regulation of pH
+ GO:0007035, vacuolar acidification
+ GO:0007036, vacuolar calcium ion homeostasis
+ GO:0007042, lysosomal lumen acidification
+ GO:0007301, ovarian ring canal formation
+ GO:0007416, synaptogenesis
+ GO:0008302, ring canal formation, actin assembly
+ GO:0009268, response to pH
+ GO:0030002, anion homeostasis
+ GO:0030003, cation homeostasis
+ GO:0030004, monovalent inorganic cation homeostasis
+ GO:0030005, di-, tri-valent inorganic cation homeostasis
+ GO:0030007, potassium ion homeostasis
+ GO:0030026, manganese ion homeostasis
+ GO:0030319, di-, tri-valent inorganic anion homeostasis
+ GO:0030320, monovalent inorganic anion homeostasis
+ GO:0030641, hydrogen ion homeostasis
+ GO:0030642, sulfate ion homeostasis
+ GO:0030643, phosphate ion homeostasis
+ GO:0030644, chloride ion homeostasis
+ GO:0030725, ring canal formation
+ GO:0030726, testicular ring canal formation
+ GO:0045851, negative regulation of pH
+ GO:0045852, positive regulation of pH
- GO:0046908, negative regulation of crystal formation
+ GO:0046916, transition metal ion homeostasis
+ GO:0048169, regulation of long-term neuronal synaptic plasticity
+ GO:0048170, positive regulation of long-term neuronal synaptic plasticity
+ GO:0048171, negative regulation of long-term neuronal synaptic plasticity
Terms movements under GO Slim term 'biological_process ; GO:0008150'
+ GO:0000079, regulation of CDK activity
+ GO:0006469, negative regulation of protein kinase activity
+ GO:0007194, negative regulation of adenylate cyclase activity
+ GO:0030193, regulation of blood coagulation
+ GO:0030194, positive regulation of blood coagulation
+ GO:0030195, negative regulation of blood coagulation
+ GO:0042730, fibrinolysis
+ GO:0045736, negative regulation of CDK activity
+ GO:0045737, positive regulation of CDK activity
+ GO:0045761, regulation of adenylate cyclase activity
+ GO:0045762, positive regulation of adenylate cyclase activity
+ GO:0045859, regulation of protein kinase activity
+ GO:0045860, positive regulation of protein kinase activity
Terms movements under GO Slim term 'metabolism ; GO:0008152'
- GO:0030092, regulation of flagellum biogenesis
- GO:0045718, negative regulation of flagellum biogenesis
- GO:0045724, positive regulation of flagellum biogenesis
Terms movements under GO Slim term 'biosynthesis ; GO:0009058'
- GO:0030092, regulation of flagellum biogenesis
- GO:0045718, negative regulation of flagellum biogenesis
- GO:0045724, positive regulation of flagellum biogenesis
Terms movements under GO Slim term 'cell organization and biogenesis ; GO:0016043'
- GO:0007301, ovarian ring canal formation
- GO:0008302, ring canal formation, actin assembly
- GO:0030725, ring canal formation
- GO:0030726, testicular ring canal formation
Terms movements under GO Slim term 'cell homeostasis ; GO:0019725'
+ GO:0042103, positive regulation of T-cell homeostatic proliferation
+ GO:0046013, regulation of T-cell homeostatic proliferation
+ GO:0046014, negative regulation of T-cell homeostatic proliferation
SourceForge items closed this month:
SF id Resolution SF item title GO ids added, if any
695398 Accepted germ cell nucleus GO:0043073-43082
801353 Accepted Actin-activated ATPase activity GO:0030898-30899
830950 Accepted vesicle docking [none]
833076 Accepted membrane fusion query [none]
835130 Accepted Golgi to endosome transport -various [none]
849100 Duplicate query protein taggin activity [none]
849757 Fixed protein storage vacuole tpv? [none]
854029 Accepted Golgi vesicle budding/ Golgi vesicle targetting [none]
856821 Fixed TPV protein-ER targeting (0) [none]
856822 Duplicate new term request spindle kinetochore attachment [none]
856858 Accepted NTR: HOPS complex GO:0030897
857144 Accepted general regulation term in process GO:0050789-50796
857611 Fixed chemi-mechanical coupling GO:0006943 [none]
857620 Fixed term move: ring canal formation GO:0043062-43063
858830 Fixed Receptor activity generic def change [none]
861039 Fixed Multifunctional transporter terms for obsoletion GO:0050833
862264 Fixed flagella biogenesis? GO:0043064
862300 Fixed regulation of synapse GO:0050803-50808
862308 Fixed structural constituent activity [none]
862348 Accepted Sleep patterns GO:0050802
864436 Fixed Regulation of survival gene products [none]
869226 Accepted Obsoletion: negative regulation of crystal formation GO:0050801
870909 Fixed EC Update GO:0050800
871238 Accepted new term: gastrulation (sensu vertebrata) GO:0048276
871993 Works For Me new relationship for budding? [none]
872001 Accepted new term: binary fission GO:0043093
872416 Fixed Obsoletion: diazepam-binding inhibitor activity GO:0050809
873051 Fixed Obsoletion: antifreeze activity GO:0050824-50826
873056 Fixed Obsoletion: ice nucleation activity [none]
873136 Fixed Obsoletion: a few more process-y function terms GO:0050827-50828
873707 Fixed Obsoletion: lamin/chromatin binding [none]
873732 Fixed Obsoletion: phosphoserine/phosphothreonine binding GO:0050815-0050816
873741 Duplicate response to nicotine [none]
874757 Rejected unknown [none]
875351 Accepted Epothilone biosynthesis GO:0050813-50814
876389 Fixed inconsistant molybdate parents [none]
876397 Fixed spelling error for term 43065 [none]
877552 Rejected protein phosphatase type 5 activity [none]
877615 Rejected protein phosphatase type 7 activity [none]
877811 Later flower development (GO:0009908) [none]
878200 Fixed Synonym for TGFbeta receptor signaling pathway [none]
881997 Fixed Obsoletion: cell adhesion molecule terms GO:0050839-50840
882073 Accepted amino acid sensing related GO:0043090-43092
882170 Works For Me spindle/kinetochore attachment [none]
882858 Fixed TAIR term name changes [none]
883046 Rejected molecular-switch [none]
884742 Accepted add synonym [none]
884745 None Can`t load cell_comp file [none]
885513 Accepted New Definition for GO:0042571, circulating Ig [none]
885680 Accepted new synonym for beta catenin destruction complex [none]
886009 Fixed DNA Damage Reversal [none]
Statistics:
Component: 1388 terms, 83.2% defined (1155 terms defined)
Function: 7280 terms, 85.5% defined (6227 terms defined)
Process: 8176 terms, 89.4% defined (7313 terms defined)
Total: 16844 terms, 87.2% defined (14695 terms defined)
Term errors
none