GO Monthly Release Notes for December 2003 ======================== Generated on Tue Feb 10 15:03:29 2004 Files used: component old: 2.430 new: 2.440 function old: 2.912 new: 2.930 process old: 2.1031 new: 2.1069 definitions old: new: 2.1586 GO Slim: Generic.0208 Key: |----1----||----2-----||-3--||4||----5----||-----------6-----------| GO:0009941 GO:0009536 TAIR D SF:575119 chloroplast envelope (obs) 1. GO ID number 2. GO-slim term(s) that new term was added under or "obs" if the term is obsolete. Terms with more than one GO-slim parent have further parents listed underneath the first parent. 3. Database that added term 4. indicates the existence of a definition for the term 5. the sourceforge request ID the term was added in response to 6. term name Columns are tab-delimited and can be imported into Excel for ease of reading. New terms in component ontology (14 new terms) GO:0001405 GO:0005623 SGD D 857730 presequence translocase-associated import motor GO:0005739 GO:0030891 GO:0005622 MAH D 816550 VCB complex GO:0005737 GO:0030892 GO:0005694 MAH D 848923 mitotic cohesin complex GO:0030893 GO:0005694 MAH D 848923 meiotic cohesin complex GO:0030894 GO:0005694 MAH D 856322 replisome GO:0030895 GO:0005634 MAH D 821166 apolipoprotein B mRNA editing enzyme complex GO:0030896 GO:0000228 MAH D 848463 checkpoint clamp complex GO:0005694 GO:0035061 GO:0005654 FB D 846582 interchromatin granule GO:0035062 GO:0005654 FB D 846582 omega speckle GO:0035068 GO:0005622 FB D 850711 micro-ribonucleoprotein complex GO:0035085 GO:0005622 FB D 828196 cilium axoneme GO:0005623 GO:0005929 GO:0035086 GO:0005622 FB D 828196 flagellar axoneme GO:0005623 GO:0043034 GO:0005737 JL D 819343 costamere GO:0043036 GO:0009536 JL D 835678 starch grain Term name changes in component ontology GO:0000325: vacuole (sensu Streptophyta) --> vacuole (sensu Magnoliophyta) GO:0000330: vacuolar lumen (sensu Streptophyta) --> vacuolar lumen (sensu Magnoliophyta) GO:0005744: mitochondrial inner membrane pre-sequence translocase complex --> mitochondrial inner membrane presequence translocase complex GO:0009705: vacuolar membrane (sensu Streptophyta) --> vacuolar membrane (sensu Magnoliophyta) New definitions for component ontology terms (2 new definitions) GO:0009568, amyloplast starch grain GO:0009569, chloroplast starch grain Term movements in component ontology: Terms movements under GO Slim term 'intracellular ; GO:0005622' + GO:0001520, outer dense fiber + GO:0001534, radial spoke + GO:0001535, radial spokehead + GO:0001536, radial spoke stalk + GO:0005858, axonemal dynein complex + GO:0005879, axonemal microtubule + GO:0005930, axoneme + GO:0005931, nexin Terms movements under GO Slim term 'cell ; GO:0005623' + GO:0001520, outer dense fiber + GO:0001534, radial spoke + GO:0001535, radial spokehead + GO:0001536, radial spoke stalk + GO:0005858, axonemal dynein complex + GO:0005879, axonemal microtubule + GO:0005930, axoneme + GO:0005931, nexin + GO:0005932, basal body Terms movements under GO Slim term 'nucleoplasm ; GO:0005654' - GO:0005657, replication fork - GO:0005658, alpha DNA polymerase:primase complex - GO:0005659, delta DNA polymerase complex - GO:0005660, delta-DNA polymerase cofactor complex - GO:0005662, DNA replication factor A complex - GO:0005663, DNA replication factor C complex - GO:0005664, nuclear origin of replication recognition complex - GO:0008622, epsilon DNA polymerase complex Terms movements under GO Slim term 'chromosome ; GO:0005694' + GO:0005657, replication fork + GO:0005658, alpha DNA polymerase:primase complex + GO:0005659, delta DNA polymerase complex + GO:0005660, delta-DNA polymerase cofactor complex + GO:0005662, DNA replication factor A complex + GO:0005663, DNA replication factor C complex + GO:0008622, epsilon DNA polymerase complex + GO:0042555, MCM complex Terms movements under GO Slim term 'cilium ; GO:0005929' - GO:0001520, outer dense fiber - GO:0001534, radial spoke - GO:0001535, radial spokehead - GO:0001536, radial spoke stalk - GO:0005858, axonemal dynein complex - GO:0005879, axonemal microtubule - GO:0005930, axoneme - GO:0005931, nexin - GO:0005932, basal body New terms in function ontology (13 new terms) GO:0001784 GO:0005515 MGI D phosphotyrosine binding GO:0001785 GO:0004872 MGI D prostaglandin J receptor activity GO:0001786 GO:0008289 MGI D phosphatidylserine binding GO:0035064 GO:0005515 FB D 850156 methylated histone residue binding GO:0035091 GO:0008289 FB D 846010 phosphoinositide binding GO:0043035 GO:0003682 JL D 836549 chromatin insulator sequence binding GO:0043047 GO:0003677 JL D 852013 single-stranded telomeric DNA binding GO:0050780 GO:0005102 AI D 856526 dopamine receptor binding GO:0050781 GO:0003824 AI D 854927 ortho-trichlorophenol reductive dehalogenase activity GO:0050782 GO:0005215 AI D galactose uniporter activity GO:0050785 GO:0004872 AI D 859003 advanced glycation end-product receptor activity GO:0050786 GO:0005102 AI D 858408 RAGE receptor binding GO:0050797 GO:0003824 AI D 862524 thymidylate synthase (FAD) activity New obsoletions in function ontology GO:0003763, chaperonin ATPase activity: represents a class of gene products, and its definition incorporates process information. GO:0008552, zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity: represents more than one molecular function. GO:0008567, dynein ATPase activity: represents a class of gene products, and its definition incorporates process information. GO:0008570, myosin ATPase activity: represents a class of gene products, and its definition incorporates process information. GO:0008571, non-chaperonin molecular chaperone ATPase activity: represents a class of gene products. GO:0008572, nucleoplasmin ATPase activity: represents a class of gene products, and its definition incorporates process information. GO:0008573, peroxisome-assembly ATPase activity: incorporates process information. GO:0008576, vesicle-fusing ATPase activity: incorporates process information. GO:0015303, galactose, glucose uniporter activity: represents two molecular functions. GO:0015305, lactose, galactose:hydrogen symporter activity: represents two molecular functions. GO:0015339, cobalt, zinc uptake permease activity: represents more than one molecular function. GO:0015340, zinc, cadmium uptake permease activity: represents more than one molecular function. GO:0015342, zinc, iron permease activity: represents more than one molecular function. GO:0015543, lactose/glucose efflux transporter activity: represents two molecular functions. GO:0016821, hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement: incorporates process information. Term name changes in function ontology GO:0004791: thioredoxin-disulfide reductase activity --> thioredoxin disulfide reductase activity GO:0005214: structural constituent of cuticle (sensu Insecta) activity --> structural constituent of cuticle (sensu Insecta) GO:0005332: GABA:sodium symporter activity --> gamma-aminobutyric acid:sodium symporter activity GO:0008010: structural constituent of larval cuticle (sensu Insecta) activity --> structural constituent of larval cuticle (sensu Insecta) GO:0008011: structural constituent of pupal cuticle (sensu Insecta) activity --> structural constituent of pupal cuticle (sensu Insecta) GO:0008012: structural constituent of adult cuticle (sensu Insecta) activity --> structural constituent of adult cuticle (sensu Insecta) GO:0008597: calcium-dependent protein serine/threonine phosphatase, intrinsic regulator activity --> calcium-dependent protein serine/threonine phosphatase regulator activity GO:0008599: protein phosphatase type 1, intrinsic regulator activity --> protein phosphatase type 1 regulator activity GO:0008601: protein phosphatase type 2A, intrinsic regulator activity --> protein phosphatase type 2A regulator activity GO:0008603: cAMP-dependent protein kinase, intrinsic regulator activity --> cAMP-dependent protein kinase regulator activity GO:0008605: protein kinase CK2, intrinsic regulator activity --> protein kinase CK2 regulator activity GO:0008607: phosphorylase kinase, intrinsic regulator activity --> phosphorylase kinase regulator activity GO:0015185: L-gamma-aminobutyrate transporter activity --> L-gamma-aminobutyric acid transporter activity GO:0015539: hexuronate (glucuronate/galacturonate) porter activity --> hexuronate porter activity GO:0015619: thiamin, thiamin pyrophosphate porter activity --> thiamin pyrophosphate porter activity GO:0016536: cyclin-dependent protein kinase 5 activator, intrinsic regulator activity --> cyclin-dependent protein kinase 5 activator regulator activity GO:0016538: cyclin-dependent protein kinase, intrinsic regulator activity --> cyclin-dependent protein kinase regulator activity GO:0017020: myosin phosphatase, intrinsic regulator activity --> myosin phosphatase regulator activity GO:0019909: [pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic regulator activity --> [pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity GO:0019914: cyclin-dependent protein kinase activating kinase, intrinsic regulator activity --> cyclin-dependent protein kinase activating kinase regulator activity GO:0030020: extracellular matrix structural constituent conferring tensile strength activity --> extracellular matrix structural constituent conferring tensile strength GO:0030021: extracellular matrix structural constituent conferring compression resistance activity --> extracellular matrix structural constituent conferring compression resistance GO:0030022: adhesive extracellular matrix constituent activity --> adhesive extracellular matrix constituent GO:0030023: extracellular matrix constituent conferring elasticity activity --> extracellular matrix constituent conferring elasticity GO:0030281: structural constituent of cutaneous appendage activity --> structural constituent of cutaneous appendage GO:0030359: protein phosphatase type 2B, intrinsic regulator activity --> protein phosphatase type 2B regulator activity GO:0030362: protein phosphatase type 4, intrinsic regulator activity --> protein phosphatase type 4 regulator activity GO:0042329: structural constituent of cuticle (sensu Nematoda) activity --> structural constituent of cuticle (sensu Nematoda) New definitions for function ontology terms (19 new definitions) GO:0003691, double-stranded telomeric DNA binding GO:0003832, beta-alanyl-dopamine hydrolase activity GO:0003833, beta-alanyl-dopamine synthase activity GO:0004954, prostanoid receptor activity GO:0004955, prostaglandin receptor activity GO:0004956, prostaglandin D receptor activity GO:0004957, prostaglandin E receptor activity GO:0004958, prostaglandin F receptor activity GO:0004960, thromboxane receptor activity GO:0004961, thromboxane A2 receptor activity GO:0008599, protein phosphatase type 1 regulator activity GO:0008601, protein phosphatase type 2A regulator activity GO:0016501, prostacyclin receptor activity GO:0016536, cyclin-dependent protein kinase 5 activator regulator activity GO:0016821, hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement GO:0019888, protein phosphatase regulator activity GO:0019914, cyclin-dependent protein kinase activating kinase regulator activity GO:0030359, protein phosphatase type 2B regulator activity GO:0030362, protein phosphatase type 4 regulator activity New term merges in function ontology GO:0008596 has been merged into GO:0004723, calcium-dependent protein serine/threonine phosphatase activity GO:0008598 has been merged into GO:0000163, protein phosphatase type 1 activity GO:0008600 has been merged into GO:0000158, protein phosphatase type 2A activity GO:0008602 has been merged into GO:0004691, cAMP-dependent protein kinase activity GO:0008604 has been merged into GO:0004682, protein kinase CK2 activity GO:0008606 has been merged into GO:0004689, phosphorylase kinase activity GO:0016535 has been merged into GO:0016534, cyclin-dependent protein kinase 5 activator activity GO:0016537 has been merged into GO:0004693, cyclin-dependent protein kinase activity GO:0017019 has been merged into GO:0017018, myosin phosphatase activity GO:0019737 has been merged into GO:0008177, succinate dehydrogenase (ubiquinone) activity GO:0019906 has been merged into GO:0004741, [pyruvate dehydrogenase (lipoamide)] phosphatase activity GO:0019913 has been merged into GO:0019912, cyclin-dependent protein kinase activating kinase activity GO:0030358 has been merged into GO:0030357, protein phosphatase type 2B activity GO:0030361 has been merged into GO:0030360, protein phosphatase type 4 activity Term movements in function ontology: Terms movements under GO Slim term 'chaperone activity ; GO:0003754' - GO:0003763, chaperonin ATPase activity Terms movements under GO Slim term 'catalytic activity ; GO:0003824' - GO:0003763, chaperonin ATPase activity - GO:0008552, zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity - GO:0008567, dynein ATPase activity - GO:0008569, minus-end-directed microtubule motor activity - GO:0008570, myosin ATPase activity - GO:0008571, non-chaperonin molecular chaperone ATPase activity - GO:0008572, nucleoplasmin ATPase activity - GO:0008573, peroxisome-assembly ATPase activity - GO:0008574, plus-end-directed microtubule motor activity - GO:0008576, vesicle-fusing ATPase activity - GO:0016821, hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement - GO:0019909, [pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity Terms movements under GO Slim term 'protein kinase activity ; GO:0004672' - GO:0008603, cAMP-dependent protein kinase regulator activity - GO:0008605, protein kinase CK2 regulator activity - GO:0008607, phosphorylase kinase regulator activity - GO:0016534, cyclin-dependent protein kinase 5 activator activity - GO:0016536, cyclin-dependent protein kinase 5 activator regulator activity - GO:0016538, cyclin-dependent protein kinase regulator activity - GO:0019912, cyclin-dependent protein kinase activating kinase activity - GO:0019914, cyclin-dependent protein kinase activating kinase regulator activity Terms movements under GO Slim term 'protein phosphatase activity ; GO:0004721' - GO:0008597, calcium-dependent protein serine/threonine phosphatase regulator activity - GO:0008599, protein phosphatase type 1 regulator activity - GO:0008601, protein phosphatase type 2A regulator activity - GO:0017020, myosin phosphatase regulator activity - GO:0030359, protein phosphatase type 2B regulator activity - GO:0030362, protein phosphatase type 4 regulator activity Terms movements under GO Slim term 'transporter activity ; GO:0005215' - GO:0008552, zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity - GO:0015303, galactose, glucose uniporter activity - GO:0015305, lactose, galactose:hydrogen symporter activity - GO:0015339, cobalt, zinc uptake permease activity - GO:0015340, zinc, cadmium uptake permease activity - GO:0015342, zinc, iron permease activity - GO:0015543, lactose/glucose efflux transporter activity Terms movements under GO Slim term 'enzyme regulator activity ; GO:0030234' + GO:0008599, protein phosphatase type 1 regulator activity + GO:0008601, protein phosphatase type 2A regulator activity + GO:0019909, [pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity + GO:0030359, protein phosphatase type 2B regulator activity + GO:0030362, protein phosphatase type 4 regulator activity New terms in process ontology (87 new terms) GO:0001779 GO:0007275 MGI D 847639 natural killer cell differentiation GO:0007582 GO:0009607 GO:0030154 GO:0001780 GO:0019725 MGI D neutrophil homeostasis GO:0001781 GO:0008219 MGI D programmed cell death, neutrophils GO:0019725 GO:0001782 GO:0019725 MGI D B-cell homeostasis GO:0001783 GO:0008219 MGI D programmed cell death, B-cells GO:0019725 GO:0001787 GO:0007582 MGI D natural killer cell proliferation GO:0008283 GO:0009607 GO:0035063 GO:0016043 FB D 846582 nuclear speck organization and biogenesis GO:0035065 GO:0006259 FB D 850156 regulation of histone acetylation GO:0006464 GO:0016043 GO:0035066 GO:0006259 FB D 850156 positive regulation of histone acetylation GO:0006464 GO:0016043 GO:0035067 GO:0006259 FB D 850156 negative regulation of histone acetylation GO:0006464 GO:0016043 GO:0035069 GO:0007275 FB D 845984 larval midgut histolysis GO:0016265 GO:0035070 GO:0007275 FB D 845984 salivary gland histolysis GO:0016265 GO:0035071 GO:0007275 FB D 845984 salivary gland cell death GO:0008219 GO:0016265 GO:0035072 GO:0007275 FB D 845984 ecdysone-mediated induction of salivary gland cell death GO:0008219 GO:0009719 GO:0016265 GO:0035073 GO:0007275 FB D 845984 pupariation GO:0035074 GO:0007275 FB D 845984 pupation GO:0035075 GO:0007275 FB D 845984 response to ecdysone GO:0009719 GO:0035076 GO:0007165 FB D 845984 ecdysone receptor-mediated signaling pathway GO:0007275 GO:0009719 GO:0035077 GO:0007275 FB D 845984 ecdysone-mediated polytene chromosome puffing GO:0009719 GO:0016043 GO:0035078 GO:0007275 FB D 845984 induction of programmed cell death by ecdysone GO:0008219 GO:0009719 GO:0035079 GO:0016043 FB D 845984 polytene chromosome puffing GO:0035080 GO:0006950 FB D 845984 heat shock-mediated polytene chromosome puffing GO:0009628 GO:0016043 GO:0035081 GO:0008219 FB D 845984 induction of programmed cell death by hormones GO:0035082 GO:0007275 FB D 828196 axoneme biogenesis GO:0016043 GO:0035083 GO:0007275 FB D 828196 cilium axoneme biogenesis GO:0016043 GO:0035084 GO:0007275 FB D 828196 flagellum axoneme biogenesis GO:0016043 GO:0035087 GO:0008152 FB D 860412 RNA interference, siRNA loading onto RISC GO:0040029 GO:0035088 GO:0007010 FB D 861164 establishment and/or maintenance of apical/basal cell polarity GO:0035089 GO:0007010 FB D 861164 establishment of apical/basal cell polarity GO:0035090 GO:0007010 FB D 861164 maintenance of apical/basal cell polarity GO:0035092 GO:0000003 FB D 852727 sperm chromatin condensation GO:0006259 GO:0016043 GO:0030154 GO:0035093 GO:0000003 FB D 852727 spermatogenesis, exchange of chromosomal proteins GO:0006259 GO:0016043 GO:0030154 GO:0043037 GO:0006412 JL D translation GO:0043038 GO:0006519 JL D amino acid activation GO:0008152 GO:0043039 GO:0006519 JL D tRNA aminoacylation GO:0008152 GO:0043040 GO:0006519 JL D tRNA aminoacylation for nonribosomal peptide biosynthesis GO:0008152 GO:0009058 GO:0043041 GO:0006519 JL D nonribosomal amino acid activation GO:0008152 GO:0009058 GO:0043042 GO:0006519 JL D amino acid adenylation by nonribosomal peptide synthase GO:0008152 GO:0009058 GO:0043043 GO:0009058 JL D peptide biosynthesis GO:0043044 GO:0006259 JL D 820585 ATP-dependent chromatin remodeling GO:0016043 GO:0043045 GO:0006259 JL D 823454 DNA methylation during embryonic development GO:0007275 GO:0040029 GO:0043046 GO:0000003 JL D 823454 DNA methylation during gametogenesis GO:0006259 GO:0040029 GO:0043048 GO:0006629 JL D 854677 dolichyl monophosphate biosynthesis GO:0009058 GO:0043049 GO:0007275 JL D 857245 otic placode formation GO:0043050 GO:0007610 JL D 848674 pharyngeal pumping GO:0043051 GO:0007610 JL D 848674 regulation of pharyngeal pumping GO:0043052 GO:0009605 JL D 848674 thermotaxis GO:0043053 GO:0007275 JL D 848674 dauer entry (sensu Nematoda) GO:0043054 GO:0007275 JL D 848674 dauer exit (sensu Nematoda) GO:0043055 GO:0007275 JL D 848674 maintenance of dauer (sensu Nematoda) GO:0043056 GO:0007610 JL D 848674 forward locomotion GO:0043057 GO:0007610 JL D 848674 backward locomotion GO:0043058 GO:0007610 JL D 848674 regulation of backward locomotion GO:0008150 GO:0043059 GO:0007610 JL D 848674 regulation of forward locomotion GO:0008150 GO:0043060 GO:0007049 JL D 848674 meiotic metaphase I plate congression GO:0043061 GO:0007049 JL D 848674 meiotic metaphase II plate congression GO:0050761 GO:0008152 AI D 848869 depsipeptide metabolism GO:0050762 GO:0008152 AI D 848869 depsipeptide catabolism GO:0009056 GO:0050763 GO:0008152 AI D 848869 depsipeptide biosynthesis GO:0009058 GO:0050764 GO:0006810 AI D 840056 regulation of phagocytosis GO:0050765 GO:0006810 AI D 840056 negative regulation of phagocytosis GO:0050766 GO:0006810 AI D 840056 positive regulation of phagocytosis GO:0050767 GO:0007275 AI D 852597 regulation of neurogenesis GO:0050768 GO:0007275 AI D 852597 negative regulation of neurogenesis GO:0050769 GO:0007275 AI D 852597 positive regulation of neurogenesis GO:0050770 GO:0007275 AI D 852597 regulation of axonogenesis GO:0050771 GO:0007275 AI D 852597 negative regulation of axonogenesis GO:0050772 GO:0007275 AI D 852597 positive regulation of axonogenesis GO:0050773 GO:0007275 AI D 852597 regulation of dendrite morphogenesis GO:0050774 GO:0007275 AI D 852597 negative regulation of dendrite morphogenesis GO:0050775 GO:0007275 AI D 852597 positive regulation of dendrite morphogenesis GO:0050776 GO:0009607 AI D 837195 regulation of immune response GO:0050777 GO:0009607 AI D 837195 negative regulation of immune response GO:0050778 GO:0009607 AI D 837195 positive regulation of immune response GO:0050779 GO:0008152 AI D 795921 RNA destabilization GO:0050783 GO:0008152 AI D cocaine metabolism GO:0050784 GO:0008152 AI D 859003 cocaine catabolism GO:0009056 GO:0050787 GO:0009628 AI D 840031 detoxification of mercury ion GO:0050788 GO:0009628 AI D 840031 sequestration of mercury ion GO:0050789 GO:0008150 AI D 857144 regulation of biological process GO:0050790 GO:0008150 AI D 857144 regulation of enzyme activity GO:0050791 GO:0007582 AI D 857144 regulation of physiological process GO:0008150 GO:0050792 GO:0008150 AI D 857144 regulation of viral life cycle GO:0016032 GO:0050793 GO:0007275 AI D 857144 regulation of development GO:0008150 GO:0050794 GO:0008150 AI D 857144 regulation of cellular process GO:0050795 GO:0007610 AI D 857144 regulation of behavior GO:0008150 GO:0050796 GO:0007267 AI D 857144 regulation of insulin secretion GO:0007582 New obsoletions in process ontology GO:0006341, chromatin insulator sequence binding: represents a molecular function and not a biological process. GO:0006628, mitochondrial translocation: its definition was equivalent to that of the biological process term 'mitochondrial matrix protein import' GO:0030150 while the term name 'mitochondrial translocation' has a broader meaning; this led to mis-annotation. Term name changes in process ontology GO:0000161: MAPKKK cascade (osmolarity sensing) --> MAPKKK cascade during osmolarity sensing GO:0000167: activation of MAPKKK (osmolarity sensing) --> activation of MAPKKK during osmolarity sensing GO:0000168: activation of MAPKK (osmolarity sensing) --> activation of MAPKK during osmolarity sensing GO:0000169: activation of MAPK (osmolarity sensing) --> activation of MAPK during osmolarity sensing GO:0000173: inactivation of MAPK (osmolarity sensing) --> inactivation of MAPK during osmolarity sensing GO:0000196: MAPKKK cascade (cell wall biogenesis) --> MAPKKK cascade during cell wall biogenesis GO:0000197: activation of MAPKKK (cell wall biogenesis) --> activation of MAPKKK during cell wall biogenesis GO:0000198: activation of MAPKK (cell wall biogenesis) --> activation of MAPKK during cell wall biogenesis GO:0000199: activation of MAPK (cell wall biogenesis) --> activation of MAPK during cell wall biogenesis GO:0000200: inactivation of MAPK (cell wall biogenesis) --> inactivation of MAPK during cell wall biogenesis GO:0000201: nuclear translocation of MAPK (cell wall biogenesis) --> nuclear translocation of MAPK during cell wall biogenesis GO:0000202: MAPKKK cascade (sporulation sensu Saccharomyces) --> MAPKKK cascade during sporulation (sensu Saccharomyces) GO:0000203: activation of MAPKKK (sporulation sensu Saccharomyces) --> activation of MAPKKK during sporulation (sensu Saccharomyces) GO:0000204: activation of MAPKK (sporulation sensu Saccharomyces) --> activation of MAPKK during sporulation (sensu Saccharomyces) GO:0000205: activation of MAPK (sporulation sensu Saccharomyces) --> activation of MAPK during sporulation (sensu Saccharomyces) GO:0000206: inactivation of MAPK (sporulation sensu Saccharomyces) --> inactivation of MAPK during sporulation (sensu Saccharomyces) GO:0000207: nuclear translocation of MAPK (sporulation sensu Saccharomyces) --> nuclear translocation of MAPK during sporulation (sensu Saccharomyces) GO:0000208: nuclear translocation of MAPK (osmolarity sensing) --> nuclear translocation of MAPK during osmolarity sensing GO:0000381: regulation of alternative nuclear spliceosomal mRNA splicing --> regulation of alternative nuclear mRNA splicing, via spliceosome GO:0006338: chromatin modeling --> chromatin remodeling GO:0006418: amino acid activation --> tRNA aminoacylation for protein translation GO:0006731: coenzymes and prosthetic group metabolism --> coenzyme and prosthetic group metabolism GO:0007224: smoothened signaling pathway --> smoothened receptor signaling pathway GO:0007226: regulation of smoothened by patched --> regulation of smoothened receptor activity by patched GO:0007288: axoneme assembly --> sperm axoneme assembly GO:0007368: determination of left/right asymmetry --> determination of left/right symmetry GO:0007582: physiological processes --> physiological process GO:0008589: regulation of smoothened signaling pathway --> regulation of smoothened receptor signaling pathway GO:0030438: MAPKKK cascade (sporulation sensu Fungi) --> MAPKKK cascade during sporulation (sensu Fungi) GO:0030439: activation of MAPK (sporulation sensu Fungi) --> activation of MAPK during sporulation (sensu Fungi) GO:0030440: activation of MAPKK (sporulation sensu Fungi) --> activation of MAPKK during sporulation (sensu Fungi) GO:0030441: activation of MAPKKK (sporulation sensu Fungi) --> activation of MAPKKK during sporulation (sensu Fungi) GO:0030442: inactivation of MAPK (sporulation sensu Fungi) --> inactivation of MAPK during sporulation (sensu Fungi) GO:0030443: nuclear translocation of MAPK (sporulation sensu Fungi) --> nuclear translocation of MAPK during sporulation (sensu Fungi) GO:0030466: chromatin silencing at silent mating-type cassettes (sensu Fungi) --> chromatin silencing at silent mating-type cassette (sensu Fungi) GO:0030509: BMP receptor signaling pathway --> BMP signaling pathway GO:0030833: regulation of actin polymerization --> regulation of actin filament polymerization GO:0030834: regulation of actin depolymerization --> regulation of actin filament depolymerization GO:0030835: negative regulation of actin depolymerization --> negative regulation of actin filament depolymerization GO:0030836: positive regulation of actin depolymerization --> positive regulation of actin filament depolymerization GO:0030837: negative regulation of actin polymerization --> negative regulation of actin filament polymerization GO:0030838: positive regulation of actin polymerization --> positive regulation of actin filament polymerization GO:0035042: exchange of chromosomal proteins --> fertilization, exchange of chromosomal proteins GO:0042478: regulation of eye photoreceptor development --> regulation of eye photoreceptor cell development GO:0042479: positive regulation of eye photoreceptor development --> positive regulation of eye photoreceptor cell development GO:0042480: negative regulation of eye photoreceptor development --> negative regulation of eye photoreceptor cell development GO:0045685: regulation of glia cell differentiation --> regulation of glial cell differentiation GO:0045686: negative regulation of glia cell differentiation --> negative regulation of glial cell differentiation GO:0045687: positive regulation of glia cell differentiation --> positive regulation of glial cell differentiation GO:0045877: negative regulation of smoothened by patched --> negative regulation of smoothened receptor activity by patched GO:0045878: positive regulation of smoothened by patched --> positive regulation of smoothened receptor activity by patched GO:0046138: coenzymes and prosthetic group biosynthesis --> coenzyme and prosthetic group biosynthesis GO:0046139: coenzymes and prosthetic group catabolism --> coenzyme and prosthetic group catabolism GO:0046532: regulation of photoreceptor differentiation --> regulation of photoreceptor cell differentiation GO:0046533: negative regulation of photoreceptor differentiation --> negative regulation of photoreceptor cell differentiation GO:0046534: positive regulation of photoreceptor differentiation --> positive regulation of photoreceptor cell differentiation GO:0048024: regulation of nuclear spliceosomal mRNA splicing --> regulation of nuclear mRNA splicing, via spliceosome GO:0048025: negative regulation of nuclear spliceosomal mRNA splicing --> negative regulation of nuclear mRNA splicing, via spliceosome GO:0048026: positive regulation of nuclear spliceosomal mRNA splicing --> positive regulation of nuclear mRNA splicing, via spliceosome GO:0048176: regulation of hepacyte growth factor biosynthesis --> regulation of hepatocyte growth factor biosynthesis GO:0048177: positive regulation of hepacyte growth factor biosynthesis --> positive regulation of hepatocyte growth factor biosynthesis GO:0048178: negative regulation of hepacyte growth factor biosynthesis --> negative regulation of hepatocyte growth factor biosynthesis GO:0048209: Regulation of Golgi vesicle targeting --> regulation of Golgi vesicle targeting New definitions for process ontology terms (10 new definitions) GO:0006341, chromatin insulator sequence binding GO:0006345, loss of chromatin silencing GO:0006627, mitochondrial processing GO:0007288, sperm axoneme assembly GO:0008314, gurken receptor signaling pathway GO:0008346, larval walking behavior GO:0008628, induction of apoptosis by hormones GO:0009059, macromolecule biosynthesis GO:0009060, aerobic respiration GO:0009061, anaerobic respiration New term merges in process ontology GO:0007609 has been merged into GO:0009591, perception of mechanical stimulus Term movements in process ontology: Terms movements under GO Slim term 'reproduction ; GO:0000003' - GO:0008314, gurken receptor signaling pathway Terms movements under GO Slim term 'DNA metabolism ; GO:0006259' - GO:0006341, chromatin insulator sequence binding Terms movements under GO Slim term 'transcription ; GO:0006350' - GO:0006364, rRNA processing - GO:0006365, 35S primary transcript processing - GO:0030489, processing of 27S pre-rRNA - GO:0030490, processing of 20S pre-rRNA Terms movements under GO Slim term 'protein biosynthesis ; GO:0006412' - GO:0019184, nonribosomal peptide biosynthesis Terms movements under GO Slim term 'protein modification ; GO:0006464' + GO:0006627, mitochondrial processing Terms movements under GO Slim term 'amino acid and derivative metabolism ; GO:0006519' + GO:0006418, tRNA aminoacylation for protein translation + GO:0006419, alanyl-tRNA aminoacylation + GO:0006420, arginyl-tRNA aminoacylation + GO:0006421, asparaginyl-tRNA aminoacylation + GO:0006422, aspartyl-tRNA aminoacylation + GO:0006423, cysteinyl-tRNA aminoacylation + GO:0006424, glutamyl-tRNA aminoacylation + GO:0006425, glutaminyl-tRNA aminoacylation + GO:0006426, glycyl-tRNA aminoacylation + GO:0006427, histidyl-tRNA aminoacylation + GO:0006428, isoleucyl-tRNA aminoacylation + GO:0006429, leucyl-tRNA aminoacylation + GO:0006430, lysyl-tRNA aminoacylation + GO:0006431, methionyl-tRNA aminoacylation + GO:0006432, phenylalanyl-tRNA aminoacylation + GO:0006433, prolyl-tRNA aminoacylation + GO:0006434, seryl-tRNA aminoacylation + GO:0006435, threonyl-tRNA aminoacylation + GO:0006436, tryptophanyl-tRNA aminoacylation + GO:0006437, tyrosyl-tRNA aminoacylation + GO:0006438, valyl-tRNA aminoacylation Terms movements under GO Slim term 'transport ; GO:0006810' - GO:0006628, mitochondrial translocation - GO:0048242, epinephrine secretion - GO:0048243, norepinephrine secretion Terms movements under GO Slim term 'response to stress ; GO:0006950' + GO:0001767, establishment of lymphocyte polarity + GO:0001768, establishment of T-cell polarity + GO:0001769, establishment of B-cell polarity + GO:0001770, establishment of natural killer cell polarity + GO:0030595, immune cell chemotaxis + GO:0048246, macrophage chemotaxis + GO:0048247, lymphocyte chemotaxis Terms movements under GO Slim term 'mitochondrion organization and biogenesis ; GO:0007005' - GO:0006628, mitochondrial translocation Terms movements under GO Slim term 'development ; GO:0007275' + GO:0001754, eye photoreceptor cell differentiation + GO:0007288, sperm axoneme assembly - GO:0007459, photoreceptor fate commitment (sensu Drosophila) - GO:0007467, photoreceptor differentiation (sensu Drosophila) - GO:0008314, gurken receptor signaling pathway + GO:0009998, negative regulation of retinal cone cell fate + GO:0042670, retinal cone cell differentiation + GO:0042671, retinal cone cell fate determination + GO:0042672, retinal cone cell fate specification + GO:0042673, regulation of retinal cone cell fate + GO:0042674, cone cell differentiation (sensu Drosophila) + GO:0042706, eye photoreceptor cell fate commitment - GO:0045673, regulation of photoreceptor differentiation (sensu Drosophila) - GO:0045674, negative regulation of photoreceptor differentiation (sensu Drosophila) - GO:0045675, positive regulation of photoreceptor differentiation (sensu Drosophila) + GO:0046551, retinal cone cell fate commitment Terms movements under GO Slim term 'biological_process ; GO:0008150' + GO:0001558, regulation of cell growth + GO:0001559, interpretation of nuclear/cytoplasmic ratio to regulate cell growth + GO:0001560, interpretation of external signals that regulate cell growth + GO:0006884, regulation of cell volume + GO:0007116, regulation of budding + GO:0007621, negative regulation of female receptivity + GO:0008284, positive regulation of cell proliferation + GO:0008285, negative regulation of cell proliferation + GO:0009786, regulation of asymmetric cytokinesis + GO:0009992, cellular osmoregulation + GO:0016239, positive regulation of macroautophagy + GO:0016241, regulation of macroautophagy + GO:0016242, negative regulation of macroautophagy + GO:0016243, regulation of autophagic vacuole size + GO:0030307, positive regulation of cell growth + GO:0030308, negative regulation of cell growth + GO:0030322, stabilization of membrane potential + GO:0030503, regulation of redox homeostasis + GO:0030888, regulation of B-cell proliferation + GO:0030889, negative regulation of B-cell proliferation + GO:0030890, positive regulation of B-cell proliferation + GO:0040012, regulation of locomotion + GO:0040013, negative regulation of locomotion + GO:0040017, positive regulation of locomotion + GO:0042102, positive regulation of T-cell proliferation + GO:0042103, positive regulation of resting T-cell proliferation + GO:0042104, positive regulation of activated T-cell proliferation + GO:0042127, regulation of cell proliferation + GO:0042129, regulation of T-cell proliferation + GO:0042130, negative regulation of T-cell proliferation + GO:0042320, regulation of REM sleep + GO:0042321, negative regulation of sleep + GO:0042322, negative regulation of REM sleep + GO:0042323, negative regulation of non-REM sleep + GO:0042391, regulation of membrane potential + GO:0042749, regulation of circadian sleep/wake cycle + GO:0042752, regulation of circadian rhythm + GO:0042753, positive regulation of circadian rhythm + GO:0042754, negative regulation of circadian rhythm + GO:0045069, regulation of viral genome replication + GO:0045070, positive regulation of viral genome replication + GO:0045071, negative regulation of viral genome replication + GO:0045091, regulation of retroviral genome replication + GO:0045187, regulation of sleep + GO:0045188, regulation of non-REM sleep + GO:0045434, negative regulation of female receptivity, post-mating + GO:0045592, regulation of ovarian cumulus cell differentiation + GO:0045593, negative regulation of ovarian cumulus cell differentiation + GO:0045594, positive regulation of ovarian cumulus cell differentiation + GO:0045769, negative regulation of asymmetric cytokinesis + GO:0045770, positive regulation of asymmetric cytokinesis + GO:0045771, negative regulation of autophagic vacuole size + GO:0045772, positive regulation of autophagic vacuole size + GO:0045781, negative regulation of budding + GO:0045782, positive regulation of budding + GO:0045794, negative regulation of cell volume + GO:0045795, positive regulation of cell volume + GO:0045837, negative regulation of membrane potential + GO:0045838, positive regulation of membrane potential + GO:0045869, negative regulation of retroviral genome replication + GO:0045870, positive regulation of retroviral genome replication + GO:0045924, regulation of female receptivity + GO:0045925, positive regulation of female receptivity + GO:0045938, positive regulation of sleep + GO:0046005, positive regulation of REM sleep + GO:0046006, regulation of activated T-cell proliferation + GO:0046007, negative regulation of activated T-cell proliferation + GO:0046008, regulation of female receptivity, post-mating + GO:0046009, positive regulation of female receptivity, post-mating + GO:0046010, positive regulation of non-REM sleep + GO:0046013, regulation of resting T-cell proliferation + GO:0046014, negative regulation of resting T-cell proliferation + GO:0046596, regulation of virion penetration + GO:0046597, negative regulation of virion penetration + GO:0046598, positive regulation of virion penetration + GO:0046640, regulation of alpha-beta T-cell proliferation + GO:0046641, positive regulation of alpha-beta T-cell proliferation + GO:0046642, negative regulation of alpha-beta T-cell proliferation + GO:0046646, regulation of gamma-delta T-cell proliferation + GO:0046647, negative regulation of gamma-delta T-cell proliferation + GO:0046648, positive regulation of gamma-delta T-cell proliferation + GO:0046662, regulation of oviposition + GO:0046782, regulation of viral transcription + GO:0048042, regulation of oviposition, post-mating + GO:0048145, regulation of fibroblast proliferation + GO:0048146, positive regulation of fibroblast proliferation + GO:0048147, negative regulation of fibroblast proliferation + GO:0050434, positive regulation of viral transcription + GO:0050670, regulation of lymphocyte proliferation + GO:0050671, positive regulation of lymphocyte proliferation + GO:0050672, negative regulation of lymphocyte proliferation + GO:0050675, regulation of urothelial cell proliferation + GO:0050676, negative regulation of urothelial cell proliferation + GO:0050677, positive regulation of urothelial cell proliferation + GO:0050678, regulation of epithelial cell proliferation + GO:0050679, positive regulation of epithelial cell proliferation + GO:0050680, negative regulation of epithelial cell proliferation Terms movements under GO Slim term 'metabolism ; GO:0008152' + GO:0001717, conversion of seryl-tRNAsec to selenocys-tRNAsec + GO:0001718, conversion of met-tRNAf to fmet-tRNA + GO:0001720, conversion of lysyl-tRNA to pyrrolysyl-tRNA + GO:0006418, tRNA aminoacylation for protein translation + GO:0006419, alanyl-tRNA aminoacylation + GO:0006420, arginyl-tRNA aminoacylation + GO:0006421, asparaginyl-tRNA aminoacylation + GO:0006422, aspartyl-tRNA aminoacylation + GO:0006423, cysteinyl-tRNA aminoacylation + GO:0006424, glutamyl-tRNA aminoacylation + GO:0006425, glutaminyl-tRNA aminoacylation + GO:0006426, glycyl-tRNA aminoacylation + GO:0006427, histidyl-tRNA aminoacylation + GO:0006428, isoleucyl-tRNA aminoacylation + GO:0006429, leucyl-tRNA aminoacylation + GO:0006430, lysyl-tRNA aminoacylation + GO:0006431, methionyl-tRNA aminoacylation + GO:0006432, phenylalanyl-tRNA aminoacylation + GO:0006433, prolyl-tRNA aminoacylation + GO:0006434, seryl-tRNA aminoacylation + GO:0006435, threonyl-tRNA aminoacylation + GO:0006436, tryptophanyl-tRNA aminoacylation + GO:0006437, tyrosyl-tRNA aminoacylation + GO:0006438, valyl-tRNA aminoacylation + GO:0019988, charged-tRNA modification Terms movements under GO Slim term 'biosynthesis ; GO:0009058' + GO:0019184, nonribosomal peptide biosynthesis Terms movements under GO Slim term 'response to biotic stimulus ; GO:0009607' + GO:0030595, immune cell chemotaxis + GO:0048246, macrophage chemotaxis + GO:0048247, lymphocyte chemotaxis Terms movements under GO Slim term 'response to abiotic stimulus ; GO:0009628' + GO:0015694, mercury ion transport Terms movements under GO Slim term 'protein transport ; GO:0015031' - GO:0006628, mitochondrial translocation Terms movements under GO Slim term 'cell organization and biogenesis ; GO:0016043' - GO:0006341, chromatin insulator sequence binding + GO:0007288, sperm axoneme assembly - GO:0007465, R7 cell fate commitment - GO:0045500, sevenless signaling pathway - GO:0045501, regulation of sevenless signaling pathway - GO:0045873, negative regulation of sevenless signaling pathway - GO:0045874, positive regulation of sevenless signaling pathway Terms movements under GO Slim term 'protein metabolism ; GO:0019538' - GO:0006628, mitochondrial translocation Terms movements under GO Slim term 'cell differentiation ; GO:0030154' + GO:0001751, eye photoreceptor differentiation (sensu Drosophila) + GO:0007459, photoreceptor fate commitment (sensu Drosophila) + GO:0007467, photoreceptor differentiation (sensu Drosophila) + GO:0045465, R8 differentiation + GO:0045466, R7 differentiation + GO:0048052, R1/R6 differentiation (sensu Drosophila) + GO:0048054, R2/R5 differentiation (sensu Drosophila) + GO:0048056, R3/R4 differentiation (sensu Drosophila) SourceForge items closed this month: SF id Resolution SF item title GO ids added, if any 780191 Accepted Adding MetaCyc reactions to GO GO:0046992-46998 GO:0047000-47483 GO:0047486-47495 GO:0047500-48000 GO:0050001-50426 795921 Accepted RNA destabilization activity GO:0050779 816550 Accepted pVHL-elongin C-elongin B (VCB) complex GO:0030891 819343 Accepted costamere GO:0043034 819502 Works For Me GO:0018307 enzyme active site formation [none] 820585 Accepted ATP dependent chromatin remodeling activity GO:0043044 821166 Accepted apoB mRNA editing enzyme complex GO:0030895 821197 Duplicate plasma membrane hydrogen-transporting V-type ATPases [none] 823122 Fixed Make GO:0007609 (mechanosensory perception) obsolete? [none] 823454 Accepted URGENT: 'de novo' DNA methylation GO:0043045-43046 824110 Accepted osmoregulation [none] 827547 Fixed Use of CO2 Vs carbon dioxide [none] 828196 Fixed cilia vs flagellum GO:0035082-35086 831157 None more chromatin related [none] 835678 Accepted starch grain GO:0043036 835701 Fixed EC/GO mapping [none] 836319 Accepted modification of a definition [none] 836549 Accepted Move term from process to function. GO:0043035 837195 Accepted EASY:reg. of immune response GO:0050776-50778 837931 Accepted to be fixed [none] 839145 Works For Me acetyltransferase function/process query [none] 839958 Accepted mitochondrial matrix protein import query [none] 840031 Accepted children of "response to mercury ion" GO:0050787-50788 840056 Accepted reg of phagocytosis GO:0050764-50766 840389 Fixed mRNA processing /mRNA metabolism [none] 842205 Fixed Definition for GO:0019724 B-cell mediated immunity [none] 845592 Rejected cold shock protein [none] 845770 Fixed bad ATPase terms [none] 845984 Accepted new children of metamorphosis GO:0035069-35081 846010 Accepted phosphatidylinositol binding ; GO:0005545 GO:0035091 846022 Fixed gurken receptor signaling pathway [none] 846043 Fixed extra relationships for pigmentation terms. [none] 846502 Fixed synonyms for some enzyme terms [none] 846582 Accepted speckle organization and biogenesis GO:0035061-35063 847639 Accepted New Term: natural killer cell differentiation GO:0001779 848463 Accepted heterotrimeric checkpoint clamp complex GO:0030896 848674 Accepted new term suggestions, mostly C. elegans specific GO:0043050-43061 848869 Accepted depsipeptide metabolism GO:0050761-50763 848923 Accepted cohesin compnew cohesin complexes GO:0030892-30893 849581 Accepted dopamine biosynthesis from tyrosine [none] 850156 Accepted methylated histone residue binding GO:0035064-35067 850690 Fixed meiotic recombination redundant relationship [none] 850711 Accepted micro-ribonucleoprotein complex GO:0035068 851966 Accepted transmembrane as an inaccurate synonym? [none] 852013 Accepted single-stranded telomeric DNA binding GO:0043047 852597 Accepted regulation of neurogenesis GO:0050767-50775 852704 Accepted synonym for spermatid development [none] 852727 Accepted definition for 'exchange of chromosomal proteins' GO:0035092-35093 853382 Fixed thioredoxin-disulfide reductase activity [none] 854677 Accepted dolichyl monophosphate biosynthesis GO:0043048 854821 Works For Me top level of heirarchies [none] 854927 Accepted Ortho-chlorophenol reductive dehalogenase activity GO:0050781 856322 Fixed replication fork/ replisome? GO:0030894 856526 Accepted dopamine receptor binding GO:0050780 856814 Works For Me MP GO:0006626 : protein-mitochondrial targeting [none] 857245 Accepted New Term: otic placode formation GO:0043049 857573 Duplicate Q: cardohydrate utilization GO:0007582 [none] 857730 Accepted new mito import term GO:0001405 858130 Accepted Two terms for EC:1.3.5.1 [none] 858408 Accepted advanced glycation end product receptor activity GO:0050785-50786 859003 Accepted cocaine metabolism GO:0050784-50785 GO:0050799 859889 Rejected induction of apoptosis by DNA damage [none] 860412 Accepted RNA interference\, siRNA loading onto RISC GO:0035087 860650 Duplicate parentage of 'RNA nuclear export complex' ; GO:0042565 [none] 860994 Fixed regulatory / catalytic subunit resolution [none] 861164 Accepted establishment and/or maintenance of apico-basal cell polarit GO:0035088-35090 861606 Fixed quick [none] 862524 Accepted thymidylate synthase ThyX GO:0050797 Statistics: Component: 1377 terms, 83.1% defined (1144 terms defined) Function: 7281 terms, 84.5% defined (6155 terms defined) Process: 8113 terms, 89.2% defined (7240 terms defined) Total: 16771 terms, 86.7% defined (14539 terms defined) Term errors none