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<entry dataset="TrEMBL" created="2014-09-03" modified="2021-06-02" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A059XJ33</accession>
    <name>A0A059XJ33_9ADEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">E1B protein, small T-antigen</fullName>
        </recommendedName>
    </protein>
    <organism evidence="4 6">
        <name type="scientific">California sea lion adenovirus 1</name>
        <dbReference type="NCBI Taxonomy" id="943083"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Preplasmiviricota</taxon>
            <taxon>Tectiliviricetes</taxon>
            <taxon>Rowavirales</taxon>
            <taxon>Adenoviridae</taxon>
            <taxon>Mastadenovirus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2014-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Cortes-Hinojosa G.A."/>
                <person name="Gulland F.M.D."/>
                <person name="Goldstein T."/>
                <person name="Venn-Watson S."/>
                <person name="Rivera R."/>
                <person name="Waltzek T.B."/>
                <person name="Salemi M."/>
                <person name="Wellehan J.F.X.Jr."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">Zc11-030</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="journal article" date="2015" name="Infect. Genet. Evol." volume="31" first="270" last="276">
            <title>Phylogenomic characterization of California sea lion adenovirus-1.</title>
            <authorList>
                <person name="Cortes-Hinojosa G."/>
                <person name="Gulland F.M."/>
                <person name="Goldstein T."/>
                <person name="Venn-Watson S."/>
                <person name="Rivera R."/>
                <person name="Waltzek T.B."/>
                <person name="Salemi M."/>
                <person name="Wellehan J.F.Jr."/>
            </authorList>
            <dbReference type="PubMed" id="25660039"/>
            <dbReference type="DOI" id="10.1016/j.meegid.2015.01.024"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">Zc11-030</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="3">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>Complex virome in a mesenteric lymph node from a Californian sea lion (Zalophus californianus) with polyserositis and steatitis ('skinny fat syndrome').</title>
            <authorList>
                <person name="Altan E."/>
                <person name="Delwart E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">Hanchett_2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the adenoviridae E1B 19 kDa protein family.</text>
    </comment>
    <dbReference type="EMBL" id="KJ563221">
        <property type="protein sequence ID" value="AIA22344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MT610364">
        <property type="protein sequence ID" value="QLH64698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009032603.1">
        <property type="nucleotide sequence ID" value="NC_024150.1"/>
    </dbReference>
    <dbReference type="GeneID" id="19488605"/>
    <dbReference type="KEGG" id="vg:19488605"/>
    <dbReference type="Proteomes" id="UP000116231">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000510833">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019050">
        <property type="term" value="P:suppression by virus of host apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002924">
        <property type="entry name" value="Adenovir_t-Ag_E1B_19kDa"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01691">
        <property type="entry name" value="Adeno_E1B_19K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0244">Early protein</keyword>
    <keyword evidence="3" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="2 3" id="KW-1081">Inhibition of host apoptosis by viral BCL2-like protein</keyword>
    <keyword evidence="3" id="KW-1119">Modulation of host cell apoptosis by virus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AIA22344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QLH64698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000116231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000510833"/>
        </source>
    </evidence>
    <sequence length="147" mass="16602" checksum="B8042EB88117BCF9" modified="2014-09-03" version="1">MEQLKDYSFFKEVVEHASLRTGNLYRFFFSSSLAKVVFQVYLEKVGEFDRLDSTASALLALSQGNNFLFEKLIIPELPFYSFGHILASLAFCSFCVNKADISATVSSGFILDAVCRPAWQKFMMSHNMMENQTGSSEFSLEEALTDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-09-03" modified="2021-06-02" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A059XN88</accession>
    <name>A0A059XN88_9ADEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">E1A</fullName>
        </submittedName>
    </protein>
    <organism evidence="3 5">
        <name type="scientific">California sea lion adenovirus 1</name>
        <dbReference type="NCBI Taxonomy" id="943083"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Preplasmiviricota</taxon>
            <taxon>Tectiliviricetes</taxon>
            <taxon>Rowavirales</taxon>
            <taxon>Adenoviridae</taxon>
            <taxon>Mastadenovirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2014-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Cortes-Hinojosa G.A."/>
                <person name="Gulland F.M.D."/>
                <person name="Goldstein T."/>
                <person name="Venn-Watson S."/>
                <person name="Rivera R."/>
                <person name="Waltzek T.B."/>
                <person name="Salemi M."/>
                <person name="Wellehan J.F.X.Jr."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">Zc11-030</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="journal article" date="2015" name="Infect. Genet. Evol." volume="31" first="270" last="276">
            <title>Phylogenomic characterization of California sea lion adenovirus-1.</title>
            <authorList>
                <person name="Cortes-Hinojosa G."/>
                <person name="Gulland F.M."/>
                <person name="Goldstein T."/>
                <person name="Venn-Watson S."/>
                <person name="Rivera R."/>
                <person name="Waltzek T.B."/>
                <person name="Salemi M."/>
                <person name="Wellehan J.F.Jr."/>
            </authorList>
            <dbReference type="PubMed" id="25660039"/>
            <dbReference type="DOI" id="10.1016/j.meegid.2015.01.024"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Zc11-030</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="3">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>Complex virome in a mesenteric lymph node from a Californian sea lion (Zalophus californianus) with polyserositis and steatitis ('skinny fat syndrome').</title>
            <authorList>
                <person name="Altan E."/>
                <person name="Delwart E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">Hanchett_2</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KJ563221">
        <property type="protein sequence ID" value="AIA22343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MT610364">
        <property type="protein sequence ID" value="QLH64697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009032602.1">
        <property type="nucleotide sequence ID" value="NC_024150.1"/>
    </dbReference>
    <dbReference type="GeneID" id="19488634"/>
    <dbReference type="KEGG" id="vg:19488634"/>
    <dbReference type="Proteomes" id="UP000116231">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000510833">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019048">
        <property type="term" value="P:modulation by virus of host process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014410">
        <property type="entry name" value="Aden_E1A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02703">
        <property type="entry name" value="Adeno_E1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0244">Early protein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIA22343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QLH64697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000116231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000510833"/>
        </source>
    </evidence>
    <sequence length="245" mass="27078" checksum="EDF9F87331683759" modified="2014-09-03" version="1">MPLITLHFSKELLEMVANCLPEDARPPHPYDLLDLEHQPSLHDMFDIVLDSDVGGETPEIELDFPETLVNDALDYFASSPISIPSDSSPVSPDLCCHESPLSSVSEAENEDTSVEKENQDFKLDCPDYPGVNCTSCDYHRQANPEAVCSLCYMRATSHLIFEPVSPPPVSEDVFDFDVDTVLDDLIAEKDPFLSFEEVDASLQCLANGANSLFTLDSAPASTLKRKHDDDDQLEPLDLSLPKKSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A7D5NTE2</accession>
    <name>A0A7D5NTE2_9ADEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">IX</fullName>
        </submittedName>
    </protein>
    <organism evidence="7 8">
        <name type="scientific">California sea lion adenovirus 1</name>
        <dbReference type="NCBI Taxonomy" id="943083"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Preplasmiviricota</taxon>
            <taxon>Tectiliviricetes</taxon>
            <taxon>Rowavirales</taxon>
            <taxon>Adenoviridae</taxon>
            <taxon>Mastadenovirus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>Complex virome in a mesenteric lymph node from a Californian sea lion (Zalophus californianus) with polyserositis and steatitis ('skinny fat syndrome').</title>
            <authorList>
                <person name="Altan E."/>
                <person name="Delwart E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">Hanchett_2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the adenoviridae hexon-interlacing protein family.</text>
    </comment>
    <dbReference type="EMBL" id="MT610364">
        <property type="protein sequence ID" value="QLH64700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000510833">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098021">
        <property type="term" value="C:viral capsid, decoration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031423">
        <property type="term" value="F:hexon binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005641">
        <property type="entry name" value="Hexon_assoc_IX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03955">
        <property type="entry name" value="Adeno_PIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1232">Capsid decoration protein</keyword>
    <keyword evidence="4" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="3 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0946">Virion</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="112"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="70"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QLH64700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000510833"/>
        </source>
    </evidence>
    <sequence length="156" mass="17256" checksum="721A46660257EBA0" modified="2020-12-02" version="1">MDLASGSIHTSFLTARLPTWAGSRQNIQGSNMDGLPILPSNEHSASASTYKVQQXXXXXXXXXXXXPTAVQDLEQSVATLQDNQKNIQQQLDLLLNSLRNYNHRLATVENRARRVVVPEPEEDGDESNQEDNQSENHSDDEIDDDQVDPPAAGDQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-12-02" modified="2021-06-02" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A7D5NTG3</accession>
    <name>A0A7D5NTG3_9ADEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">E1B</fullName>
        </submittedName>
    </protein>
    <organism evidence="1 2">
        <name type="scientific">California sea lion adenovirus 1</name>
        <dbReference type="NCBI Taxonomy" id="943083"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Preplasmiviricota</taxon>
            <taxon>Tectiliviricetes</taxon>
            <taxon>Rowavirales</taxon>
            <taxon>Adenoviridae</taxon>
            <taxon>Mastadenovirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>Complex virome in a mesenteric lymph node from a Californian sea lion (Zalophus californianus) with polyserositis and steatitis ('skinny fat syndrome').</title>
            <authorList>
                <person name="Altan E."/>
                <person name="Delwart E."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">Hanchett_2</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="MT610364">
        <property type="protein sequence ID" value="QLH64699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000510833">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002612">
        <property type="entry name" value="Adeno_E1B_55kDa"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01696">
        <property type="entry name" value="Adeno_E1B_55K"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QLH64699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000510833"/>
        </source>
    </evidence>
    <sequence length="418" mass="46543" checksum="0E7E9FB1B8F46AB9" modified="2020-12-02" version="1">MAEVHDEPQHDGEPDGIIGILPRRSADRQLEVVPXXXXXAEAERLRHEVVEWEDLTYSLENLNPVYEFAEIKTHFVEPGDDLEKAIKVHAKVALRENCEYVLDKPLHIFNSCYIIGNGAKIIITSVLSNWIKVFPLKLGPSVIALYGVTWTNCVFENNSNASDPSYSLFSLFTCCRFVGCLFSGFTGTCIETDSEIEVVGCTFTACYKCVHSKSSLQAVCKGGVFNKCMMGIVSQAPAVITCCTFLETYCSLLAYDFVEFKHNSVTFPYGLIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKIFCGSRRGQYDLSGNFFTNCSIICTPKSVRKVEVSDSTCLNIVVMKLIGTDENEKKMRACACNNAHYCPKIKLFDISDSKVPNPYVESVLVSEVDPSSDEDDE</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>