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        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
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                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <sequence length="133" mass="15873" checksum="C111594F88C15738" modified="2020-10-07" version="1">MNVEEKNLIRELREKALGYKRISGELGISVNTIKSFCRNHKLTREHIVRTIYCKECGKELIQKEHTKKKIFCSDACKRKWWNGHRKSLSKTTMEEYICLNCHKKFKAYVAEHRKYCCHSCYIKARFQGSDDHE</sequence>
</entry>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <name>A0A6M3SUB6_9CAUD</name>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
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                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49543.1"/>
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        <location>
            <begin position="158"/>
            <end position="182"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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            <dbReference type="EMBL" id="QJD49543.1"/>
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    </evidence>
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    </evidence>
    <sequence length="182" mass="19842" checksum="D5B04F32DBD80A38" modified="2020-10-07" version="1">MTTKVITGPNTRFSYLNANEPKSINGSTPKYSASLIIPKEDTATINKIKAAIEQAYKEGESKLKGNGKSVPALSTLKTPLRDGDLERPDDEAYKNAYFVNANSPHKPGVVDGNRQEIIDTSELYSGIYGRASITFYAFNSNGNKGIACGLNNLQKLRDGEPLGGRTRAEDDFATEDDDDFLN</sequence>
</entry>
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    <accession>A0A6M3SUC1</accession>
    <name>A0A6M3SUC1_9CAUD</name>
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        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
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                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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            <dbReference type="EMBL" id="QJD49525.1"/>
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    <sequence length="152" mass="17487" checksum="E87243F340A7F7B9" modified="2020-10-07" version="1">MFFLKAKDVSIVDGPIAEAVIHVQKITSEQIEFHFGWITSVSGIGGNEYFGGMTYLVATIIYIILNDSSLKNRMIRISLDMQSEAREVAINRKIDVYHKFFKTPKNISDVSEFSFHRVATFSPENRKHDLEYFKGIIEEKEKSILSVLDSYR</sequence>
</entry>
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        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
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                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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            <end position="61"/>
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        </source>
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        <source>
            <dbReference type="EMBL" id="QJD49535.1"/>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="229" mass="26231" checksum="A2F3D6A764527959" modified="2020-10-07" version="1">MFSHGRLKQRRLEIKLSQTAIANQLNVHRSAYHNWENGRNTPNQKNLTALAAILDVPVTYFESEYNIVNNYLQLSPDNQLKAEEYVEELLLSQQTSNVIPLFSVQVLSDIQLSAGLGEGFFDEFETETIYSDEEQYGYDIAAWIEGDSMEPVYKSGEVALIRSNGFDYDGAVYALSWNDSVYIKKLYRDEDGFRMVSLNKDYPEKFIPYEDEPRIVGLVVGHFMPVEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SUD2</accession>
    <name>A0A6M3SUD2_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNHc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">phi29961_0033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="50"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QJD49553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="121" mass="14265" checksum="9ADA5FD6DC3A119B" modified="2020-10-07" version="1">MPRRPSTPCKQNGCPNLVPYGHKYCDNHKANYQLDTKSTKAKGYNAQWNKARLRYLKVQPLCVQCKVKGRLTKATVVDHITPHRGDQDLFWNQTNWQALCKSCHDRKTKTTDRYVEYTYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SUD9</accession>
    <name>A0A6M3SUD9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">phi29961_0025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QJD49545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="104" mass="11645" checksum="01626A056B33C9DD" modified="2020-10-07" version="1">MKELNRLIHDMEETAKYYLRLVDEFKKLLTTEDETAPKSNPPKNEPQKEIQLEDVRAVLATKAKDGYKEDVRALLNAYGASSLSVLDPKHFAAVLEEAGGIGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SUE8</accession>
    <name>A0A6M3SUE8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Adenine-specific methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">phi29961_0035</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015840">
        <property type="entry name" value="DNA_MeTrfase_ParB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036758">
        <property type="entry name" value="Aden_M_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ParB" evidence="4">
        <location>
            <begin position="10"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QJD49555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="416" mass="47829" checksum="4A262911EE7E66C8" modified="2020-10-07" version="1">MMTKESMTWLTLTVDQLNSASYNPRKALKKGDKEYEKIKRSIQEFGYVEPIIVNYDMTIIGGHQRLTVLKDLGFKEVQCVQVHIEDENKVKALNVALNKITGSWNEELLADLMLDLQEADFDTDLTGFEFPEIDQLFSKVHNKEVNEDDFDVDEELKKPTVAKQGDIWYLGKHQVICGDSTLPETYITLMGDKKANLVLTDPPYNVNVEETAGKIKNDNMSDSDFYKFLFAMFVNVEQNMESDASIYVFHADTEGYNFRKAFKDAGFYLSGCCIWKKNSLVLGRSPYQWQHEPCLFGWKNKGKHQWFSDRKQTTIWEYDRPKLSKEHPTMKPIQLMAYPIQNSSMRGTVVLDPFLGSGSTLIACEETGRICYGIELDEKFVDVIVKRYFEATGDQSIKVMRDGKEIKYADLVEVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SUE9</accession>
    <name>A0A6M3SUE9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Head-tail connector protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">phi29961_0043</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="CDD" id="cd08054">
        <property type="entry name" value="gp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021146">
        <property type="entry name" value="Phafe_gp6_head-tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006450">
        <property type="entry name" value="Phage_HK022_Gp6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05135">
        <property type="entry name" value="Phage_connect_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01560">
        <property type="entry name" value="put_DNA_pack"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="87" mass="10115" checksum="D3E2A8F99D09C78A" modified="2020-10-07" version="1">MLTLLEAKIYLRVDTSEEDNLIKVLIATSEELCKDVLRVDELVDTPLIRSAMLYAVAYLFEHREEANHHDLKETLYHLLGGLRKEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SUF6</accession>
    <name>A0A6M3SUF6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">phi29961_0045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QJD49565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="126" mass="13790" checksum="C83C1C45497841DF" modified="2020-10-07" version="1">MSSGGRAMRADELSRAIEKELEEYLHQTTETVVEAVDDVTDEAIATLKSTSPKRSGRYVRGWTSKETSSTSTGKTKTIHNRTPGLTHLLENGYAKQNGGRVSGRPHIGPVEQKAVQALEKKIRGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SUF7</accession>
    <name>A0A6M3SUF7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Holin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">phi29961_0053</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033644">
        <property type="term" value="C:host cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006480">
        <property type="entry name" value="Phage_holin_4_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05105">
        <property type="entry name" value="Phage_holin_4_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01593">
        <property type="entry name" value="holin_tox_secr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0204">Cytolysis</keyword>
    <keyword evidence="7" id="KW-0578">Host cell lysis by virus</keyword>
    <keyword evidence="4" id="KW-1043">Host membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-1188">Viral release from host cell</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QJD49573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="138" mass="15165" checksum="E178156DF7AC0D7A" modified="2020-10-07" version="1">MKQEVLTNKLVFSGIGGVIGSIFGEIDGFLYGLLIFMLIDYVTGIMAAIVEKNLSSSIGKKGIFKKAMIICLVAVAHMIDLQVLKQGGAVRTAVIFFYFSNEGLSILENATRIGLPVPNRIKQVLRQLNEDKEDENDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SUG6</accession>
    <name>A0A6M3SUG6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">phi29961_0055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="53" mass="6435" checksum="E7B114FB699C4E96" modified="2020-10-07" version="1">MTNDKLQDEMTYQLTMIQADRLLKSRIISEEVHQQFKEKMLEKYQPFISRLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SUJ4</accession>
    <name>A0A6M3SUJ4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CpXC protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">phi29961_0006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025682">
        <property type="entry name" value="CpXC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14353">
        <property type="entry name" value="CpXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CpXC" evidence="1">
        <location>
            <begin position="16"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QJD49526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="217" mass="25393" checksum="FB704EAB86618A47" modified="2020-10-07" version="1" precursor="true">MKRKIRMTTIFLTRTSCSNCGKQSTFERFDRVYAAKTPEIISAILDWDFFKFTCHNCNHKVLIDYPTVVVDEEQKTIIQYCADGNVDVLSMQICSLISEGVNLSEYRIRVVSDIESFVEKVQIVSVGYDDRAIELMKYMNSPLEDGDIQFNYEHMVFTKVGHENYQFMFINNQIAVASLDFSQEQYEYYLADVEDLETNTYYIDSRWAESFFRTSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SUK3</accession>
    <name>A0A6M3SUK3_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hpaIIM</name>
        <name evidence="11" type="ORF">phi29961_0016</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="9"/>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099018">
        <property type="term" value="P:evasion by virus of host restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="3 7 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1258">Restriction-modification system evasion by virus</keyword>
    <keyword evidence="5 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="10">
        <location>
            <begin position="35"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QJD49536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="408" mass="46639" checksum="5D8C642E50CF52E3" modified="2020-10-07" version="1">MTFDRHILESNRKLTTTNILSKKTTIAENLSGNDIKYLRKKYNLTQKELADALGLQKFGDRTIRRWEAEETHPSKLEQSSIQSFFNSLKNPPFIISENLPFKMIDLFAGIGGTRLGFQLTNEVETVFTSEWDKFAQKTYITNFGDTPEGDITQIDENTIPDHDILVAGFPCQAFSQAGKRLGFEDTRGTLFFDVARIIKAKRPKAFLLENVKNLKTHDKGKTYKIIISTLENLGYSTSTVLFKARDFGVPQNRERIYIVGFDKTCVNNFSEFRFPEPFHLETKLGNILQTDVDEKYTISDKLWEGHQRRKAEHKTKGNGFGYSLFNADSPYTNTLSARYYKDGSEILIEQKGKNPRKITPREAARLQGFPEEFIIPVSDTQAYKQFGNSVCVPTIHEIAKQILAVLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SUL2</accession>
    <name>A0A6M3SUL2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA primase-helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">phi29961_0026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006500">
        <property type="entry name" value="DNA_primase_phage/plasmid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045455">
        <property type="entry name" value="DUF5906"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014015">
        <property type="entry name" value="Helicase_SF3_DNA-vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014818">
        <property type="entry name" value="Phage/plasmid_primase_P4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014820">
        <property type="entry name" value="PriCT_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08706">
        <property type="entry name" value="D5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19263">
        <property type="entry name" value="DUF5906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00885">
        <property type="entry name" value="D5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00942">
        <property type="entry name" value="PriCT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01613">
        <property type="entry name" value="primase_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51206">
        <property type="entry name" value="SF3_HELICASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF3 helicase" evidence="2">
        <location>
            <begin position="476"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QJD49546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="761" mass="85702" checksum="EAC7DE785BD630D6" modified="2020-10-07" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SUM1</accession>
    <name>A0A6M3SUM1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-cytosine methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">phi29961_0036</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="3">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QJD49556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="422" mass="46772" checksum="B15806984DA4975A" modified="2020-10-07" version="1">MNQLTFIDFFAGIGGFRRGLELAGMTCIGYCEKDKFAVRSYQAMYDTEGEWYSDDITKLKPNDIPKADIWTAGSPCQNVSIAGKRAGLRAERSGLFFTLVDLLKSQSEEDKPEWLILENVKGLLSSRRGVDFLDYLLELDEAGYDLEWQVFNSKDYGVPQNRERVYTIGHLRSRGRRQVLPLQPESSGNLKQLVGGMQSYRVYDTDGISTTLVGTGGGVGAKTGLYLIDQSTTKPKVTDQARCITARYTAGSTKRTAMNSGVMEVQPILTPDRVNKRQNGRRLKEKGEPMFTLTSQDRHGVVEGIKVRNGTKQGYQVAELGDSVDLSYPASPTKRARVGKGIAHNLSCSGQMGVVVWNGRMVKIRRLTPRECFRLQGFTDDLFEKAQAVNSDAQLYKQAGNGVTVTVVYAIGKAILSCLNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SUN1</accession>
    <name>A0A6M3SUN1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">phi29961_0046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="105" mass="12499" checksum="4C30C8785D0DA04F" modified="2020-10-07" version="1">MSEKEFFKQLKALHLPIAYHHFEEGHSPSPPFMVYYSPQSENFGADNQVYHKGAQFILELYTRKKDLDVEGKIETFLTEQHLFFDKVETYIDTEQLYQVAFHFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SUP1</accession>
    <name>A0A6M3SUP1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Site-specific recombinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">phi29961_0056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011109">
        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025827">
        <property type="entry name" value="Zn_ribbon_recom_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07508">
        <property type="entry name" value="Recombinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13408">
        <property type="entry name" value="Zn_ribbon_recom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51737">
        <property type="entry name" value="RECOMBINASE_DNA_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="1">
        <location>
            <begin position="10"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Recombinase" evidence="2">
        <location>
            <begin position="164"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QJD49576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="403" mass="46952" checksum="E5AB583C30579F8E" modified="2020-10-07" version="1">MMTPQKPKLRVAAYARVSDSRLHHSLSTQVSYYSRLIQSHPDWELVGVYYDEGISGKEQSNRQGLQDLLKACDDGKIDRILTKSIARFGRNTVDLLSTVRVLRQKNIGITFEKEGIDSLSSEGELMLTLLASVAQEESHNISENLRWQIKKKFEQGQPHTPQDIYGYRWNGENYVIEPDEAKVVRQVFQWFLDGDNAPMITKKLNEQGVLTRLGNPFTVSSVREFFKQEAYFGRLVLQKTYREPFSRNPKRNNGQKNKYIVEDAHEAIVSKSYFDVVLQEKERRYKVMYQESHMHKGTFRELIECSHCGKIMITRVDSKKVHRTIRYCCRTRDRFGTSSCPSKTLSEKRILATFEDKIGFKPDKNWVTENIKKVIYDSSVGLITVFPIKGRKYELKVRKEHFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SUZ5</accession>
    <name>A0A6M3SUZ5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Site-specific recombinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">phi29961_0007</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011109">
        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07508">
        <property type="entry name" value="Recombinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51737">
        <property type="entry name" value="RECOMBINASE_DNA_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="1">
        <location>
            <begin position="43"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Recombinase" evidence="2">
        <location>
            <begin position="202"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QJD49527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="370" mass="42751" checksum="D9CE37D5A8323371" modified="2020-10-07" version="1">MVRRNSKITRQQKKIRDAFVSERTVEIIPAKREFTDVKTKKLRVAAYCRVSTFDESQSGSFELQKQTYTERINSNPDWIMAGIYADQGASGTSIKRREQFQQMLHDCRCGKIDLIIVKSVSRFARNQLDFISIYRELKALSPPVGIYIEDINLNTLDTNSEFILGIMAIVAQGESEQKSASITWSVIERFKRGIPMIPTHNLLGYTKDQYGRVVIDETEAKIVRLIYDSYIEGMTASEIASTLMTNHIPTVTGLERWTSLAVYNILRNEKYKGEIIMQKTYTVDCFSHKTRKNNGEKPKYRLKNGIPSIIPESRWDLVQELLKQPRRKSKSTSEIFVPKLYIKKLKSGKLRDFVVLDPSWKSEDIHEVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SV05</accession>
    <name>A0A6M3SV05_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II restriction-modification system restriction protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">phi29961_0017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_5" evidence="1">
        <location>
            <begin position="227"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QJD49537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="555" mass="63842" checksum="087951A0966A31F5" modified="2020-10-07" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SV12</accession>
    <name>A0A6M3SV12_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VRR-NUC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">phi29961_0027</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014883">
        <property type="entry name" value="VRR_NUC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00990">
        <property type="entry name" value="VRR_NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VRR-NUC" evidence="4">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QJD49547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="93" mass="10642" checksum="73B6FC28BABD143A" modified="2020-10-07" version="1">MREKYVEQALVKSVKARGGICPKWVSPSFSGVPDRLVFLPKGKFGLVEVKAPDQKPRKLQVSRHKLFERLGFKVYVIDRIEMIGEVLDEIDIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SV18</accession>
    <name>A0A6M3SV18_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4314 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">phi29961_0037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025463">
        <property type="entry name" value="DUF4314"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14192">
        <property type="entry name" value="DUF4314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4314" evidence="1">
        <location>
            <begin position="20"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QJD49557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="83" mass="9147" checksum="C8940163BF66E6AE" modified="2020-10-07" version="1">MVIYSYQKEGGFTMNNGAKERVECLYPVGCRVKLLEMDDPFPPPIGTLGTVYGHDDLASVLVHWDNGSGLSVVYGVDRIVKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SV29</accession>
    <name>A0A6M3SV29_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tail protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">phi29961_0047</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006490">
        <property type="entry name" value="Maj_tail_phi13"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01603">
        <property type="entry name" value="maj_tail_phi13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="196" mass="21789" checksum="78B688D18AB4D591" modified="2020-10-07" version="1">MAEKNKVTFGLQDVHWAEVTTEGSDGALTYGNVERLRGAAELTLEATGDSGSYKADNINFYTTESNDGYSGTLKVALLTQEFLTRVLGETLDDTNKVITESSNATRKNFALMFRFEGDKKETLHVLYYCYASRPTVGSKTKNGSDINEVELKFTASPRPLDQVVRRRTTEETPETVKKNWFKSVYEPTVASGGSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SV37</accession>
    <name>A0A6M3SV37_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Site-specific recombinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">phi29961_0057</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011109">
        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025827">
        <property type="entry name" value="Zn_ribbon_recom_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07508">
        <property type="entry name" value="Recombinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13408">
        <property type="entry name" value="Zn_ribbon_recom"/>
        <property type="match status" value="1"/>
    </dbReference>
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            <dbReference type="PROSITE" id="PS51737"/>
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            <dbReference type="EMBL" id="QJD49577.1"/>
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</entry>
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        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
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                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
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                <person name="Ojeda Saavedra M."/>
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                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </evidence>
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        </source>
    </evidence>
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</entry>
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        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
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                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
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            <authorList>
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                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="520" mass="59142" checksum="77237434C7B8D230" modified="2020-10-07" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SVI9</accession>
    <name>A0A6M3SVI9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tail length tape-measure protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="primary">smc_2</name>
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    </gene>
    <organism evidence="4 5">
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49569.1"/>
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        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
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        <property type="entry name" value="Phage_tape_meas"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="621"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="668"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="domain" description="PhageMin_Tail" evidence="3">
        <location>
            <begin position="315"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="58"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QJD49569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="1039" mass="111167" checksum="FC36A2C0DF676758" modified="2020-10-07" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SWM2</accession>
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            <fullName evidence="5">Macrolide-efflux pump protein</fullName>
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        <name evidence="5" type="primary">msr(D)</name>
        <name evidence="5" type="ORF">phi29961_0010</name>
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        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
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            <taxon>Duplodnaviria</taxon>
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        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
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            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49530.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="297"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="214"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QJD49530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="487" mass="54735" checksum="4011A81F079BC2DC" modified="2020-10-07" version="1">MELILKAKDISVEFKGHDVLDINELEVYDYDRIGLVGANGAGKSTLFKVLLGELIPPGCKMNHLGELAYIPQLDEVTLQEEKDFALVGKLGVEQLNIQTMSGGEETRLKIAQALSAQVHGILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLDEIVDKIWELKDGKITEYWGNYSDYLRQKEEERKRQAAEYEQFIAERARLERAAEEKRKQARKIEQKAKGSSKKKSTEGGGRLAHQKSIGSKEKKMHNAAKSLENRIAALGKVEAPEGIRRIRFRQSKALELHNPYPIVGAEINKVFGDKALFENASFQIPLGAKVALTGGNGTGKTTLIQMILNHEEGISISPKAKIGYFAQNGYKYNSNQNVMEFMQKDCDYNISEIRSVLASMGFKQNDIGKSLSVLSGGEIIKLLLAKMLMGRYNILIMDEPSNFLDIPSLEALEILMKEYTGTIVFITHDKRLLENVADVVYEIRDKKIKLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SWM7</accession>
    <name>A0A6M3SWM7_9CAUD</name>
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        <lineage>
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            <taxon>Duplodnaviria</taxon>
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            <taxon>Caudovirales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="189" mass="22169" checksum="1CA33DCBA2F4A3A4" modified="2020-10-07" version="1">MTINVNFFNYCQTQSSSTGVQPTESEVLAPMFVQDYYMDSRHSGLLRGTFRQCRIMGIPILTAFVPVAEEDYEQMVWWYNNSVNDYLKDYRKPSKNAPKISSWEAFTEKQDLPMIDDDIELYLFMDQFEFLKAKLAESNFQAPDILEMLFDGYENKEIFEKLGVQKSAGYKKVKNTQKEGLELYNKFNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SWM8</accession>
    <name>A0A6M3SWM8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">phi29961_0008</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
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            <taxon>Caudovirales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49528.1"/>
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    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="138" mass="16005" checksum="76E69232AE7A06C1" modified="2020-10-07" version="1">MRFKDFNLEVVNVERYSSDYSMTVNKNFVTFSKGIVQALEYPAHVLVAFNKDTKVMGIQVCRAKTRGAFSFSKPVGEQKGIVQVGHKTLKETLLTIMSEWKSDKRYRVEGIHIPEDKAFVFELKDFDELSDFRKNDNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SWN5</accession>
    <name>A0A6M3SWN5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="75" mass="8566" checksum="BB4B8091C6297FFD" modified="2020-10-07" version="1">MWTDGRIDYQGQKVDYIAKVSPQPSEVGIDLGCIFKLDIEVAEETIVSYDRGWELYPETEEREAILEAVLMVLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SWN7</accession>
    <name>A0A6M3SWN7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Restriction endonuclease</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">phi29961_0018</name>
    </gene>
    <organism evidence="1 2">
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018579">
        <property type="entry name" value="Restrct_endonuc_II_LlaJI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09563">
        <property type="entry name" value="RE_LlaJI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="415" mass="48500" checksum="94764E3918EDCAAC" modified="2020-10-07" version="1">MCRVATNMEGDTFVGIKAEIIEGVQEVTVNFPLGFEIAKDVETARRDIIALVSVLQAHNDEESRLRTVNVNQALKTLNFPMEAYTFVIHDFINRGTYYKETEEYYIQTLGGRINWARTIKRVQPVVQGNGFKFLKMESKKQSDTDITLLTEINKFCVYEAFLNMGWLYQLPQPEKARINYNRSQFESIIKKKMATTFNDMERRLFQSMIDILNYKDRQEEPDKFYFGTNNFQYIWENLIDYTYGIANKTSYFPRTKWDLVFETKTSKGYALEPDTIMVHNDNVFVLDAKYYKFGQTNLMKDLPPSTSINKQITYGEYVANQDLLKKLHGQNSKVYNAFLMPFSKSHEIFQTDGMYQYIGEALGEWKGQDKTYERVQGILVDVKTLVHNSARNRTQYIQELSDLISEKVDEKLANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SWP1</accession>
    <name>A0A6M3SWP1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Portal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">phi29961_0040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006944">
        <property type="entry name" value="Phage/GTA_portal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006427">
        <property type="entry name" value="Portal_HK97"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04860">
        <property type="entry name" value="Phage_portal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01537">
        <property type="entry name" value="portal_HK97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1171">Viral genome ejection through host cell envelope</keyword>
    <keyword evidence="3" id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword evidence="2" id="KW-0946">Virion</keyword>
    <keyword evidence="3" id="KW-1160">Virus entry into host cell</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QJD49560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="413" mass="46715" checksum="D75559900DFA6BDB" modified="2020-10-07" version="1">MGILELIGLKRARDKPTNSYEGSDFSYLFGRTTSGKNVNEMTALQTTAVYACVRILAEAIASLPIHVYKHTDEGKEQDVNHQLYYLLHDEPNPDMTSFVFRETLMSHLLIWGNAYAQIIRDGRGQVLALYPLLPDRMTVKRDDKGELYYVYQRSEEDNPNFKDKGNIILKKSEVLHVPGLGFDGLIGYSPIAMAKNAVGMTLATEEYGASFFANGANPGGVLEHPGILKDPSKVRESWNQVYQGTNNSHKVAVLEEGMIYKTIGIPPNEAQFLETRKFQINEIARLYRIPPHMVGDLEKSSFSNIEQQSLEFVKYTLDPWVVRFEQAFQKALLLPDEKKTYFIKFNVDGLLRGDYQSRMNGYAIGRQNGWLSTNDIRRLEDMNPLSKEEGGDLYLVNGNMTKLEDAGGFIKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SWP8</accession>
    <name>A0A6M3SWP8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">phi29961_0050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="241" mass="27114" checksum="5A8ACF9FEC6830E2" modified="2020-10-07" version="1">MIQHNALIIDGVSTASFPYKILVEDRPSFHIPTSKSQLQEHDGLSGGLVLTNKHRKAIEKAYRIHLIGATEEQINEFSALLTREGFWLESERMKMTRYWCYKVDSFDIVQDNLGVFSMEVTFLCHPTRYFKKVSEYTLTKNGMIPLLGSALSYPKITVSGKSTGETSFTIGEQVIGLEQLNKTLVMDNDPSHPSFLTESGELVHWSGDFITLDANQKDKKVGVVLGTGITSLHIEILWGWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SWQ0</accession>
    <name>A0A6M3SWQ0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DEAD-DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">phi29961_0028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="13"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QJD49548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="458" mass="52209" checksum="3A9CE11A74D200D7" modified="2020-10-07" version="1">MKLTLHNYQVVAKDFIIGHPYAAVILDMGMGKTATTLSAVNELMFDRFEVTKVLVIAPLRVANTVWSDEIEQWSELRNLRYSKIVGTPKQRKVALQKDADIYIVNRENLPWLVEQCSPYFKWDMVVIDELSSFKSWQSKRFKAFMTMRPYMKRVVGLTGTPSSNGLMDLFAEFKVIDGGERLGRFIGEFRSRYFEEGRRNGNIVYEYIPMDYAECQIQDKISDITISMKALDYLDMPELISTKKLVRMSEKEKEKYIQFKKEYVLSELDGLEVTAANAASLMNKLVQLSNGAVYSDDHTVVPLHEQKLDALEDILESANGEPVLVAYWFKHDLARITGRLEKLKVTSRVLKTEEDIREWNKGNVPVGLIHPAGAGHGLNLQKGGHHLVWFGLTWSLELYQQTNARLWRQGQEAETVVIQHIVTEGTIDEEILKALGNKDAQQERLIEAVKAQVGGTDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SWQ7</accession>
    <name>A0A6M3SWQ7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Terminase small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">phi29961_0038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006448">
        <property type="entry name" value="Phage_term_ssu_P27"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05119">
        <property type="entry name" value="Terminase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01558">
        <property type="entry name" value="sm_term_P27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QJD49558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="158" mass="17876" checksum="B480065D2B6E61CF" modified="2020-10-07" version="1">MSDLAQRGCKPKPTGLKVLEGNLGKRPLNHKEPKPTKKAPRCPSWLEEDAKKEWKRMSKVLESMGLLTDMDMTAFAGYCQAYARWKEAEEFLTKHGSIIKTPNGYLQQVPQVSIAQTNMKIMLKFSEQFGLTPSARSRIQADSSDGEQDEMESLLREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SWR2</accession>
    <name>A0A6M3SWR2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">phi29961_0048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="139" mass="16253" checksum="4C3A111EDD84449A" modified="2020-10-07" version="1">MRKQVTICGKVYPLASNAYTPIAYKEQFGKDYFQDLFQMINAKSILDQLNQLEEGEELTAQNMDVSILSDFDMTFFHRLFWVFAKSANPRVKAFDVFFMEMEELPIQEIGPVLMEMLNQGMSTRKKSMKPMKRVKKSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SWS4</accession>
    <name>A0A6M3SWS4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ADP-ribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">phi29961_0058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003540">
        <property type="entry name" value="ADP-ribosyltransferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03496">
        <property type="entry name" value="ADPrib_exo_Tox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ADPrib_exo_Tox" evidence="2">
        <location>
            <begin position="66"/>
            <end position="183"/>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF03496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QJD49578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="191" mass="21738" checksum="DB850A7D05AE72C6" modified="2020-10-07" version="1">MNEFCYKLKGKILRTGQKWDLLSSSQADVPLFVAKYLNNEPPRYVGKIPSDEYIIASSGPTINGRLRSGSVDEKIENIYQTLKKYSTKADIVVYRGVSMETLEKMVESAQVEGCIDFKEKGFLHTSLVKGFEFRDPYKKLRIKIPKGTNAFYVGNLNNEETHYYEVIIQKGAKLKVISIDDYINCELVGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SX62</accession>
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        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="protein sequence ID" value="QJD49522.1"/>
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    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
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        <source>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
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            <authorList>
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                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SX81</accession>
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        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
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                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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    </dbReference>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="45" mass="5368" checksum="92CE575BF4AEC474" modified="2020-10-07" version="1">MGLWVLIGLYFGYMTIRDDIRNKVERKAKQNKEKLSQTPLSRKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SX88</accession>
    <name>A0A6M3SX88_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methionine adenosyltransferase</fullName>
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        </recommendedName>
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    <gene>
        <name evidence="17" type="primary">metK</name>
        <name evidence="17" type="ORF">phi29961_0032</name>
    </gene>
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        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
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        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the AdoMet synthase family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
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        <property type="entry name" value="PTHR11964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="SSF55973"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="13" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-AdoMet_synt_N" evidence="14">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_M" evidence="15">
        <location>
            <begin position="98"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_C" evidence="16">
        <location>
            <begin position="208"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QJD49552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="345" mass="38149" checksum="6A7ABD32AF8822FC" modified="2020-10-07" version="1">MIISSEQVSVGHPDKICDQISDAILTECLKYDKSSRVAVETLIKDNQVVVAGEISTRHYFNLENIVRQVVEPLGMKNVRVTNLLGLQSSDIAQGVDDGGAGDQGMMFGYATDETPEYLPLPYVLATRVLEKLMSLGHPLLGKDAKAQVSYDYEKKRIDTFLVSIQHTEIANLAKVKRIVTEAMMSVALRYRQNLDFKVLVNPTGRFVLGGSFADAGVTGRKIVADTYGGFAHHGGGAFSGKDPSKVDRSAAYMARKIAKDIVREGYAKRCEVQLAYAIGVAEPVSVYVETFGTSRYTSTQLEGMIRERYDLTPQGIIKELHLLNVDYTKTSCFGHFTKAYLPWEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SX99</accession>
    <name>A0A6M3SX99_9CAUD</name>
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        <name evidence="3" type="ORF">phi29961_0042</name>
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    <organism evidence="3 4">
        <name type="scientific">Streptococcus phage phi29961</name>
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            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="QJD49562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Genome"/>
    </dbReference>
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        <property type="entry name" value="Phage_capsid"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05065">
        <property type="entry name" value="Phage_capsid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01554">
        <property type="entry name" value="major_cap_HK97"/>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QJD49562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="395" mass="44444" checksum="E1DA6CF9E2846BC5" modified="2020-10-07" version="1">MDKILELREKRAKVWDKAKNFLDSCRDEKGMISQEDSEHYDKLEQEVVDLGKEIDRLERQERIERELSQATSAAIVSQPRTDAGGDEKTGTASTVYNQSFWKNVRQKNFFDVNNTLNIGNDGQGGYLVPDEYENRLIKALEEENFFRRLATIIKTSNGERKIPVVTGHGTAAWMDENGTYPESEETFGQVTLGAYKVGTAIKISEELIHDSVFDLESYMAEEFARRIGSKEEEAFLIGDGSGKPTGVFTTVTEGVTSTGANITFDDVMDLYHSLKSPYRKNSVWILNDSTIKALRKLKDNNGNYIWQPSVQAGVPDMILNRPYYTSSYAPEIASGQKVLAFGDFSHYWISDRQGRSFKRLNELYATSGQVGFLGSQRVDGKLVLPEAVKVLTMKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3SXB1</accession>
    <name>A0A6M3SXB1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Structural protein</fullName>
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        <name evidence="2" type="ORF">phi29961_0052</name>
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    <organism evidence="2 3">
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        <lineage>
            <taxon>Viruses</taxon>
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            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DUF859"/>
    </dbReference>
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        <property type="entry name" value="DUF859"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QJD49572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="618" mass="66580" checksum="380139332B966FF9" modified="2020-10-07" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3T6F8</accession>
    <name>A0A6M3T6F8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">phi29961_0001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
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            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Genome"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="45" mass="5660" checksum="8E577703B808FA62" modified="2020-10-07" version="1">MFLKNPHNYHFFNKNFEFQTFIVEKKFLFKIYFVLDFVDSLVLFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3T6G9</accession>
    <name>A0A6M3T6G9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <organism evidence="1 2">
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        <lineage>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Genome"/>
    </dbReference>
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        <property type="entry name" value="DUF5960"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19385">
        <property type="entry name" value="DUF5960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="99" mass="12369" checksum="3F79BCDE8F1F1F21" modified="2020-10-07" version="1">MNQLEFQRNHLQMDYYSESYQDFERDFYRYSNMNIPLTFLTDDILKTMATSRKNYFVLNKEKSRDNRDHFFIFEVRTLEENPLIYHYTYKKTTTYLAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3T6H9</accession>
    <name>A0A6M3T6H9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">phi29961_0021</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
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            <taxon>Caudovirales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Genome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLAc" evidence="1">
        <location>
            <begin position="375"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QJD49541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="651" mass="73833" checksum="C9B5389AB8EA13C0" modified="2020-10-07" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3T6J0</accession>
    <name>A0A6M3T6J0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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        <lineage>
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            <taxon>Duplodnaviria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Genome"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="71" mass="8446" checksum="1CFAB2A37C254DD9" modified="2020-10-07" version="1">MYTTKEEENNTMTKRQQEKLNALLTEIAKEELFVETLEKRWSDNLDFYDVSVWGIKRALERAYEAGQKSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3T6K1</accession>
    <name>A0A6M3T6K1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Clp protease-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">clpP</name>
        <name evidence="2" type="ORF">phi29961_0041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
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            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QJD49561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="228" mass="25257" checksum="549868C07C5CD05F" modified="2020-10-07" version="1">MHKFWNWAKNEGERTLFLNGVIASESWFGDEVTPQLFKDELLSEQGDITLWINSPGGDVFAAAQIYNMLMDYKGAVTVNIDGIAASAASVIAMAGTIVNMSPVSMMMIHNPATFASGDKREMEKAIQLLNEVKESIINAYEIKTSLSRQKLSNLMDGETWLNAKKAVELGFADQIIFDGTHDNDESQDAYAFSMQTVTNQVVAKCEQLIDKPKVAVSTLEKRLQLLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3T6L3</accession>
    <name>A0A6M3T6L3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Structural protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">phi29961_0051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007119">
        <property type="entry name" value="Phage_minor_struct_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010572">
        <property type="entry name" value="Prophage_Tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044051">
        <property type="entry name" value="Prophage_tail_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06605">
        <property type="entry name" value="Prophage_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18994">
        <property type="entry name" value="Prophage_tailD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01665">
        <property type="entry name" value="put_anti_recept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prophage_tailD1" evidence="2">
        <location>
            <begin position="24"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Prophage_tail" evidence="1">
        <location>
            <begin position="108"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QJD49571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="967" mass="108138" checksum="B8DBD4055CE31A7E" modified="2020-10-07" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3T9J1</accession>
    <name>A0A6M3T9J1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Site-specific recombinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">phi29961_0004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011109">
        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025827">
        <property type="entry name" value="Zn_ribbon_recom_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07508">
        <property type="entry name" value="Recombinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13408">
        <property type="entry name" value="Zn_ribbon_recom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Recombinase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Zn_ribbon_recom" evidence="2">
        <location>
            <begin position="59"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QJD49524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="155" mass="17782" checksum="FDAA97E0BE15EFC5" modified="2020-10-07" version="1">MQKTSVKGPIKQNKVKNKGELPQYYVENNHKAIVDKETFDAVQAVLDRTEKGKGSTTLFCSKLVCGDCGHYFGSKVWHSTSKYRRVIYQCNEKYKGEKKCTTPHVTENEIKDWFVSVINKVISNKDEIIQNLEMLLDVGKSSDLERIFRDTQSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3T9J6</accession>
    <name>A0A6M3T9J6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">phi29961_0014</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="75" mass="8729" checksum="8E5C3F2672464A01" modified="2020-10-07" version="1">MKLKDILELGTYGFNPNCKVEIFCMDNFEERLENEGFDEILIPQNDDAKIYPYAFLIEDSILIAMTEVDDDINEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3T9K1</accession>
    <name>A0A6M3T9K1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">phi29961_0024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021229">
        <property type="entry name" value="DUF2800"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10926">
        <property type="entry name" value="DUF2800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="385" mass="43432" checksum="310F44CC2FD8D682" modified="2020-10-07" version="1">MRQYLKKLEELVMTNHAILSASASHRWLNCPPSARLTEDLPDTTSDFAIEGSDAHELCAYLVEKALGRNARDPTEDLTFYNDEMQECAEEYRNYVMEQVEKARGYSRDPTVLIEQRLDFSKWVPEGFGTGDCIIVADGRLQVIDYKHGLGVQVDADHNPQMMCYALGALEMFDGLYNFDNVTMTIFQPRKHNISTFKIEKTELLEWAENVLTPKAELAFKGEGEMQSGKHCQFCKLKNVCRKRAEDNLALAKMEFADPASLDNEDIAEILPKLDLLISWANDIKAYALNQATDGHPIPGYKLVEGRSVRKFSDESAVSQAVIEAGYDPYEKKLLTITAMTKLLGKKTFNDLLGGLIIKPSGKPTLVPIDDSRQEMNLAKNEFKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3T9K7</accession>
    <name>A0A6M3T9K7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HTH domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">phi29961_0034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="134" mass="15373" checksum="897916A18372A242" modified="2020-10-07" version="1">MNDFKAKQVWKMRNEGLGYRKIANLLDLSLTAVKRYCSTNPHLKGYGQAVVAMISDGQRNGQLCKECLKPIEQPRKGRTKQFCSDSCRRKNWVTQHPEKADSHVCELCGKTFTAYGSPRRKFCSRTCARTPRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3T9L1</accession>
    <name>A0A6M3T9L1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Head closure protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">phi29961_0044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008767">
        <property type="entry name" value="Phage_SPP1_head-tail_adaptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038666">
        <property type="entry name" value="SSP1_head-tail_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05521">
        <property type="entry name" value="Phage_H_T_join"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01563">
        <property type="entry name" value="gp16_SPP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="QJD49564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="109" mass="12656" checksum="E3D1D814691273E4" modified="2020-10-07" version="1">MKIAPLNQRVLFKKRVITQDDIGNETSQFTNLFSRWASVNQANSDEIFEVGQTKRKLQLIVTLRYDSEVASLDTTNTQLIFQGKSFNILSIDHVFFEKKMVKCRVEEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2020-10-07" modified="2021-04-07" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A6M3T9L6</accession>
    <name>A0A6M3T9L6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">phi29961_0054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Streptococcus phage phi29961</name>
        <dbReference type="NCBI Taxonomy" id="2729190"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Siphoviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2020" name="J. Clin. Microbiol." volume="0" first="0" last="0">
            <title>Population genomic molecular epidemiological study of macrolide resistant Streptococcus pyogenes in Iceland, 1995-2016: Identification of a large clonal population with a pbp2x mutation conferring reduced in vitro beta-lactam susceptibility.</title>
            <authorList>
                <person name="Southon S.B."/>
                <person name="Beres S.B."/>
                <person name="Kachroo P."/>
                <person name="Ojeda Saavedra M."/>
                <person name="Erlendsdottir H."/>
                <person name="Haraldsson G."/>
                <person name="Yerramilli P."/>
                <person name="Pruitt L."/>
                <person name="Zhu L."/>
                <person name="Musser J.M."/>
                <person name="Kristinsson K.G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MT311968">
        <property type="protein sequence ID" value="QJD49574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000509622">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007921">
        <property type="entry name" value="CHAP_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50911">
        <property type="entry name" value="CHAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C51" evidence="1">
        <location>
            <begin position="5"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QJD49574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000509622"/>
        </source>
    </evidence>
    <sequence length="258" mass="27944" checksum="CD8CF9945D992C28" modified="2020-10-07" version="1">MTSKEKVVANALSKVNTKVTVPTNPYGGQCVALIDKIVQEETGKNMSYTNAIDCLDKAKANGFQVTYDAVGVNPQAGDFYVIRVPSHSFGHIGVCLADSDGTGLEGVEQNVDGYSDSNRNGVNDQLEVGGYTRRVSRKWYSDGRLVDSHSGGLVGYMVGWFRLPYEVATSTKKVETSEDEDMKNFVVRSKSGKQGYVAVVNGAVFGIGHIDTVVQLQSAGAAHLTLDDGDFNRFLESQKFDDEKLVASVQALEKAIKQ</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>