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<entry dataset="TrEMBL" created="2018-09-12" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2U8U8C2</accession>
    <name>A0A2U8U8C2_9VIRU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Replicase large subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RdRp</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Opuntia virus 2</name>
        <dbReference type="NCBI Taxonomy" id="2200716"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Kitrinoviricota</taxon>
            <taxon>Alsuviricetes</taxon>
            <taxon>Martellivirales</taxon>
            <taxon>Virgaviridae</taxon>
            <taxon>Tobamovirus</taxon>
            <taxon>unclassified Tobamovirus</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-07" db="EMBL/GenBank/DDBJ databases">
            <title>A novel strategy of RNA-seq for identifying of RNA plant viruses in Opuntia ficus-indica from Mexico.</title>
            <authorList>
                <person name="Salgado O H."/>
                <person name="De La Torre A R."/>
                <person name="Sanchez N J."/>
                <person name="Pallas V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="MF434821">
        <property type="protein sequence ID" value="AWM98766.2"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000289810">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008174">
        <property type="term" value="F:mRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039694">
        <property type="term" value="P:viral RNA genome replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027351">
        <property type="entry name" value="(+)RNA_virus_helicase_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002588">
        <property type="entry name" value="Alphavirus-like_MT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007094">
        <property type="entry name" value="RNA-dir_pol_PSvirus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001788">
        <property type="entry name" value="Tymovirus_RNA-dep_RNA_pol"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00978">
        <property type="entry name" value="RdRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01443">
        <property type="entry name" value="Viral_helicase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01660">
        <property type="entry name" value="Vmethyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51743">
        <property type="entry name" value="ALPHAVIRUS_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51657">
        <property type="entry name" value="PSRV_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50507">
        <property type="entry name" value="RDRP_SSRNA_POS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-0941">Suppressor of RNA silencing</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0693">Viral RNA replication</keyword>
    <feature type="domain" description="Alphavirus-like MT" evidence="11">
        <location>
            <begin position="72"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="(+)RNA virus helicase C-terminal" evidence="10">
        <location>
            <begin position="786"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="domain" description="RdRp catalytic" evidence="9">
        <location>
            <begin position="1365"/>
            <end position="1478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AWM98766.2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000289810"/>
        </source>
    </evidence>
    <sequence length="1598" mass="180648" checksum="59E22DA25CA0A06B" modified="2020-02-26" version="2"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2020-02-26" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2U8U8D0</accession>
    <name>A0A2U8U8D0_9VIRU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Capsid protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CP</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Opuntia virus 2</name>
        <dbReference type="NCBI Taxonomy" id="2200716"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Kitrinoviricota</taxon>
            <taxon>Alsuviricetes</taxon>
            <taxon>Martellivirales</taxon>
            <taxon>Virgaviridae</taxon>
            <taxon>Tobamovirus</taxon>
            <taxon>unclassified Tobamovirus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-07" db="EMBL/GenBank/DDBJ databases">
            <title>A novel strategy of RNA-seq for identifying of RNA plant viruses in Opuntia ficus-indica from Mexico.</title>
            <authorList>
                <person name="Salgado O H."/>
                <person name="De La Torre A R."/>
                <person name="Sanchez N J."/>
                <person name="Pallas V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the virgaviridae capsid protein family.</text>
    </comment>
    <dbReference type="EMBL" id="MF434821">
        <property type="protein sequence ID" value="AWM98769.2"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000289810">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019029">
        <property type="term" value="C:helical viral capsid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001337">
        <property type="entry name" value="TMV-like_coat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036417">
        <property type="entry name" value="TMV-like_coat_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00721">
        <property type="entry name" value="TMV_coat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47195">
        <property type="entry name" value="SSF47195"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="4" id="KW-1139">Helical capsid protein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0946">Virion</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AWM98769.2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000289810"/>
        </source>
    </evidence>
    <sequence length="179" mass="19233" checksum="8B753D13A6F50CC3" modified="2020-02-26" version="1">MPYVGVSTRSLALLTPSFVRYVDVLSLIQSILGSQSFQTQSGRDQLRSQLAGLLTAPASRDVRFPEETVFVRVFDSVIEPLWLSVLAATDTRNRIIEEQMVQGPTTPEVLNATKRVDDATVACRTALSKLRSGISDNLDTVCYDRTKFELELGSAWLQPGGAPGGGNPAGSGARTGTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-09-12" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2U8U8G9</accession>
    <name>A0A2U8U8G9_9VIRU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Movement protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Cell-to-cell transport protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">MP</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Opuntia virus 2</name>
        <dbReference type="NCBI Taxonomy" id="2200716"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Kitrinoviricota</taxon>
            <taxon>Alsuviricetes</taxon>
            <taxon>Martellivirales</taxon>
            <taxon>Virgaviridae</taxon>
            <taxon>Tobamovirus</taxon>
            <taxon>unclassified Tobamovirus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-07" db="EMBL/GenBank/DDBJ databases">
            <title>A novel strategy of RNA-seq for identifying of RNA plant viruses in Opuntia ficus-indica from Mexico.</title>
            <authorList>
                <person name="Salgado O H."/>
                <person name="De La Torre A R."/>
                <person name="Sanchez N J."/>
                <person name="Pallas V."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Forms a ribonucleoprotein complex with viral RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Host cell junction</location>
            <location evidence="2">Host plasmodesma</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Host cytoplasm</location>
            <location evidence="1">Host cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the tobamovirus movement protein family.</text>
    </comment>
    <dbReference type="EMBL" id="MF434821">
        <property type="protein sequence ID" value="AWM98768.2"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000289810">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044219">
        <property type="term" value="C:host cell plasmodesma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044163">
        <property type="term" value="C:host cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046740">
        <property type="term" value="P:transport of virus in host, cell to cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001022">
        <property type="entry name" value="TMV_movement"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028919">
        <property type="entry name" value="Viral_movement"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01107">
        <property type="entry name" value="MP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00964">
        <property type="entry name" value="MOVEMENT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1031">Host cell junction</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <keyword evidence="5 8" id="KW-0916">Viral movement protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AWM98768.2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000289810"/>
        </source>
    </evidence>
    <sequence length="254" mass="27854" checksum="7E2BDFEC10B42F6E" modified="2020-02-26" version="2">MAIDTYSKLLEPKRFIKPGFWYCTPLGKSKSPLKFCNICVTDIVKVKSVGSFSFCLSVYKTVRPDHRSFKFARLVGVTISGVWHFDKGLPGSAVIALIDSRITDVNLSILSKVVVSASQAGEFQFTFSPNFSITMNDLKRNPIELIVDLQGLPLCDGFEPLSLELGFLFYYSDSALSSSLGAKIKLLQSETNVESGDIPDHVFDEVVSEVDLNSVIPKARNLRNALSVSSKSSSALERAVVSNKFAKGAKANKR</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>