<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="http://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
 xsi:schemaLocation="http://uniprot.org/uniprot http://www.uniprot.org/docs/uniprot.xsd">
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKV9</accession>
    <name>A0A2P1CKV9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_4</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="372" mass="42139" checksum="FD44F077CABC7A4E" modified="2018-05-23" version="1">MNVNAISARVSEIAALGISELTKRQLMLVELVADIVNHETENGYLTMKEGNLPLTMMPYWNSLMIYLDDAGFELLGNGHFSAAFKHHLLPQKVIKVGFKKEDSGAAYAAFCRMNQGKQGIPTIHNIQRHAGCYTVVLDELRPLVTTLWGDVDENYEDENVVDQFNTVRGIISCNETFGGGADQLLDALAETAKEIRKFFDGIASFDMHSGNAMVDHNGHVIITDPVSFTDKAVEHSRDGFMIDPEELLKEIEQLAELRIIERCRERKAKRDPKGQFRLDLKQRQKRRKEYKKAERFWKRDAAKRALKAHNRNVAFKELGSTLWMKAYFNLPDAKMVEMEAQIAAKVANRNHKAIALGQALDIDKELDAMFQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKW2</accession>
    <name>A0A2P1CKW2_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ebrios_8</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006266">
        <property type="term" value="P:DNA ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041559">
        <property type="entry name" value="DNA_ligase_ATP-dep_T7_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016306">
        <property type="entry name" value="DNA_ligase_T7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17879">
        <property type="entry name" value="DNA_ligase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001600">
        <property type="entry name" value="DNA_ligase_phage_T3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="3">
        <location>
            <begin position="175"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="2">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001600-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AVJ51891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="340" mass="38577" checksum="07857AF28D9C87BB" modified="2018-05-23" version="1">MMNIKTNPYKAVSFNEKSVEKALKRSHYLIADIKYDGVRGNTLVKPSQGACWLSRVSKPIPAIEHLNDGAARWDNLLKDNRCMFPTGFMLDGELMVDGVDFNTGSGLLRTKWLDSKNQEFHNEFLPRNVKKSEKIPFRLDAGLLKVVIYAVLPIEVVESGDDYPVKNLLMQEHVKNMLPLLRAHFPEISWQAAESHEVYDMTELSALYEMKREEGHEGLIVKDPSDIYKRGKKSGWYKLKPEQEADGIIQGVNWGTKGLANEGKVIGFSVLLESGRLVDANNVSRVLMDEFTANVKEHGADYYNGWQCQIAYMEETKDGSLRHPSFSCFRGTEDNPTEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKW3</accession>
    <name>A0A2P1CKW3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_10</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AVJ51893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="83" mass="9246" checksum="27C6C66C44926DF6" modified="2018-05-23" version="1">MLMNNYLTNPAHPLSPLNPISPISIWNQGCSREETVEVVSQRQHRELDPKEKLVLGAGFGVCLALLLTLVLVMVFGEIGRPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKW4</accession>
    <name>A0A2P1CKW4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_3</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036207">
        <property type="entry name" value="B-form_Ocr"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101059">
        <property type="entry name" value="SSF101059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="174" mass="20012" checksum="0CE9232332C9FB75" modified="2018-05-23" version="1">MKRNANAYYELLAAAVEAFNVRIQEDQLTEHHDYHAALHEVVDKMVPHCYWEIFMVMAADGIDVEFDDAGQMPDTKDVTRILQARIYEALYNDVPSDSGIEWYEGEEEEESEEPCEWYVINDEESGPYVVAYYDSLEAAIEAANERYNTLGKRCHVEDDVSSEVLYKPVPTANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKX1</accession>
    <name>A0A2P1CKX1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_20</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035156">
        <property type="entry name" value="DUF5471"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17565">
        <property type="entry name" value="DUF5471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="72" mass="8037" checksum="F629C020FBE5D086" modified="2018-05-23" version="1">MSTMNIIKGFGRMVVRMYNREAARLNKVARAEATLARELAERSNKLSVSSMKNIDEAAKVASQAQELSKFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKX2</accession>
    <name>A0A2P1CKX2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_13</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AVJ51896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="63" mass="7583" checksum="A0DC5D8A5AD23145" modified="2018-05-23" version="1">MRNQRQAPTYRNASDDKDFPSSPHHNLCSDWCHRQWESALNQGDHRAADAYMKMYEMWKARNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKX4</accession>
    <name>A0A2P1CKX4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA polymerase inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">14</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016412">
        <property type="entry name" value="RNA_pol_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038715">
        <property type="entry name" value="RNA_pol_inhibitor_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16857">
        <property type="entry name" value="RNA_pol_inhib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="73" mass="8397" checksum="E069BCEF86035075" modified="2018-05-23" version="1">MTTLYDTTTNNNMDKGSAVVENRKFWATVQTAEHSYEMPIYAVSLEEATELAERQYVPAGFEVIRVRPCRLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKX5</accession>
    <name>A0A2P1CKX5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ebrios_18</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13392">
        <property type="entry name" value="HNH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="SSF54171"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HNHc" evidence="5">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="4">
        <location>
            <begin position="119"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AVJ51901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="173" mass="19648" checksum="303E88798CCDCEA6" modified="2018-05-23" version="1">MFSLIQLKEEAMSELFKDLVIDSESPSGLRWADTARYQQAGKPAGTLQSNPRYWVVWVNKRLYRVHRVIMCLLHDLKYASCPVVDHIDGDGSNNSIGNLRLVTHAQNSANMKTPTSNTTGVKGVSYDKRRNKYRAYVTVHGKQHTAGRFDTLEEAAEAVKKLREELHGQYARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKY0</accession>
    <name>A0A2P1CKY0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_30</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="136" mass="15751" checksum="8538113638BD0803" modified="2018-05-23" version="1">MTKKRFVSVEAVSRFHAIMWTVQHLGVPTGFRDFWDYEGYVNTLMDAAGFEEEYIMDSTTGNLVAYFAWCVSNDIHHKGDIMDVTNLVIAPEFESRELHRFLSGRFKELAELNGLQWVSRCKHDSAGTMKVYFKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKY1</accession>
    <name>A0A2P1CKY1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_24</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022611">
        <property type="entry name" value="Phage_T7_5.5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11247">
        <property type="entry name" value="DUF2675"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="100" mass="11162" checksum="AF56D935F70936A5" modified="2018-05-23" version="1">MAMTKRYKVTFEITAKLTTKDVDEFTKGLIETSRKIVEGKPVNPELRACVMAALEGGVEAAVECAYRRGVRELIRDAYNEMCSEERAATKFSPATVEVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKY2</accession>
    <name>A0A2P1CKY2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_28</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020121">
        <property type="entry name" value="Phage_T7-like_6.5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10911">
        <property type="entry name" value="DUF2717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="82" mass="9411" checksum="81488E828D9B1867" modified="2018-05-23" version="1">MLKPIQHFMNHPEDVPDVPLAVTEYLQVRFNYTYLEATGHIGHMRASGCSEAHILGFIQGLQYAANVIDEIELRKEQLNEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKY3</accession>
    <name>A0A2P1CKY3_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="5">2.7.7.7</ecNumber>
            <ecNumber evidence="5">3.1.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ebrios_23</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Replicates viral genomic DNA. This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="5"/>
    <dbReference type="EC" id="3.1.11.-" evidence="5"/>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039693">
        <property type="term" value="P:viral DNA genome replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04101">
        <property type="entry name" value="DPOL_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034699">
        <property type="entry name" value="DPOL_T7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038720">
        <property type="entry name" value="YprB_RNase_H-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13482">
        <property type="entry name" value="RNase_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 5" id="KW-1194">Viral DNA replication</keyword>
    <feature type="domain" description="POLAc" evidence="6">
        <location>
            <begin position="448"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="3'-5'exonuclease" evidence="5">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Polymerase" evidence="5">
        <location>
            <begin position="202"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="5"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic; for 3'-5' exonuclease activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic; for 3'-5' exonuclease activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="475"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
            <note>catalytic; for polymerase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="506"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="518"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="522"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="526"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AVJ51906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="704" mass="79641" checksum="C4685E215A1090EC" modified="2018-05-23" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKY9</accession>
    <name>A0A2P1CKY9_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Internal virion protein gp15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ebrios_40</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the cylindrical core that assembles on the inner surface of the capsid during capsid formation and plays a role in viral DNA ejection into the host cell. The inner core is composed of stacked rings of gp14, gp15 and gp16 proteins. Following binding to the host cell surface, the internal core is disassembled and gp15 is ejected along with gp14 and gp16 into the infected cell. Gp15 probably remains associated with gp16. The gp15-gp16 complex binds to both the viral DNA and the host inner membrane, probably escorting the leading end of the genome through the periplasm and controlling the extend of DNA translocated into the host cell.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homooctamer. Interacts with gp16; after ejection the gp15-gp16 complex composed of a gp15 octamer and a gp16 tetramer probably binds both the viral DNA and the host inner membrane. Interacts with gp14.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Host periplasm</location>
        </subcellularLocation>
        <text evidence="1">The gp15-gp16 complex spans the periplasm and the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the T7virus internal virion protein gp15 family.</text>
    </comment>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044229">
        <property type="term" value="C:host cell periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099002">
        <property type="term" value="P:viral genome ejection through host cell envelope, short tail mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04122">
        <property type="entry name" value="GP15_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038993">
        <property type="entry name" value="Gp15"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1049">Host periplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1171">Viral genome ejection through host cell envelope</keyword>
    <keyword evidence="1" id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword evidence="1" id="KW-1244">Viral short tail ejection system</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <keyword evidence="1" id="KW-1160">Virus entry into host cell</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="703"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="723"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AVJ51923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="751" mass="85090" checksum="7776770A310C199D" modified="2018-05-23" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKZ1</accession>
    <name>A0A2P1CKZ1_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Major capsid protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Major head protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_34</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Assembles with the minor capsid protein to form an icosahedral capsid. The major and minor capsid proteins are incorporated into the capsid in about a 90/10 ratio respectively. Once the capsid is formed, encapsidates one single copy of the viral genome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer. Interacts with the connector protein and the minor capsid protein. Interacts with the capsid assembly scaffolding protein; capsid proteins and scaffolding proteins form building blocks that assemble to form the procapsid, each hexamer of the major capsid protein interacting with 2 scaffolding proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The N-terminus interacts with an internal region of the major capsid protein subunit in an adjacent capsomere (intercapsomeric interactions) to stabilize the capsid.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the T7virus major capsid protein family.</text>
    </comment>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019028">
        <property type="term" value="C:viral capsid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04119">
        <property type="entry name" value="CAPSID_PROTEIN_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039009">
        <property type="entry name" value="Capsid_Gp10A/Gp10B"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AVJ51917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="345" mass="36562" checksum="1D4A517520B61255" modified="2018-05-23" version="1">MANMQGGQQLGTNQGKGANNAGDKLALFLKVFGGEVLTAFARTSVTTSRHMMRSISSGKSAQFPVLGRTNAAYLAPGANLDDIRKDIPHTEKTISIDGLLTADVLIYDIEDAMNHYDVRSEYTAQLGESLAMAADGAVLAEIAGLCNLPEATNENITGLGKATILETSKPKGELSTPAAIGIEVIELLARARAALTKNYVPASDRVFFCDPDTYSAILSSLMPNAANYAAIIDPERGSIRNVMGFEVVEVPHLTSGGAGDSREERDSTQKHQFPATVQGNAKVAKSNVIGLFMHRSAVGTVKLKDLALERARRANFQADQIIAKYAMGHGGLRPEAAGAIVFKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKZ2</accession>
    <name>A0A2P1CKZ2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Capsid and scaffold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_33</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019069">
        <property type="term" value="P:viral capsid assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008768">
        <property type="entry name" value="Phage_T7_capsid"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05396">
        <property type="entry name" value="Phage_T7_Capsid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AVJ51916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="307" mass="33570" checksum="0B49B08C5C5573DF" modified="2018-05-23" version="1">MAGESNADVYASFGVNSAVMTGDSVSTHEQNMLALDVAARDGDDAIELGEPTERDLYDNSDPFGQEDDEGRIQVRIGEDGQSVEEVSQEVETGGEQDGEPTEFTPLGDTPEALKAAQAQLAEHDAGFQEMIGMAMERGLTAETIERIQAEYDSEAGISDKSYKELAEIGYTKGFIDSYIRGQEALVEQYVAGIVEYAGGREQFDALYQHLENTNPEASKALETALENLDVATVKAIINLAGESRAKTFGRKPTRSVTQRAVPAKPQAPKKVGFESRAEMVKAMSDVRYRTDAKYRAEVEQKVWNSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKZ3</accession>
    <name>A0A2P1CKZ3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Internal virion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_38</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020335">
        <property type="entry name" value="Phage_T7_Gp13"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11090">
        <property type="entry name" value="DUF2833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="135" mass="15753" checksum="A4443FE2FDAFBABB" modified="2018-05-23" version="1">MFIRNTTPNDFTMFTPAYHDILEAKAMGITPSFPDASECVTLDHGGTPLAIGGNCGDQCWFVTSDQAWKLSRKDKMRFRKAIMEYRDKMLEKYPVLWNYVWVGNTTHIRFLKTIGAVFHEEYTRDGQFKLFTIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKZ8</accession>
    <name>A0A2P1CKZ8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA packaging protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_44</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024345">
        <property type="entry name" value="DNA_matur_Phage_T7-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11123">
        <property type="entry name" value="DNA_Packaging_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="92" mass="10326" checksum="A8F1BD04CCFFB483" modified="2018-05-23" version="1">MSKQQDKSLTVFLEMLDTAMAQRMLADLGDDDRRSPQLYNAINKLLDRHKFQIGKLQPDEHILGGLAGALEEYKAKVGDTGLTDDDLYSTIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CKZ9</accession>
    <name>A0A2P1CKZ9_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Holin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_43</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of micron-scale pores (holes) causing host cell membrane disruption and endolysin escape into the periplasmic space. Participates in determining the precise timing of host cell lysis. Participates with the endolysin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles from the host cell.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homomultimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell inner membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
        <text evidence="1">Classified as a class II holin although it seems to have only one transmembrane domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the T7likevirus holin family.</text>
    </comment>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020002">
        <property type="term" value="C:host cell plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034291">
        <property type="term" value="F:canonical holin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04108">
        <property type="entry name" value="HOLIN_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019682">
        <property type="entry name" value="Phage_T7_Gp17.5_holin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10746">
        <property type="entry name" value="Phage_holin_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0204">Cytolysis</keyword>
    <keyword evidence="1" id="KW-1030">Host cell inner membrane</keyword>
    <keyword evidence="1" id="KW-0578">Host cell lysis by virus</keyword>
    <keyword evidence="1" id="KW-1032">Host cell membrane</keyword>
    <keyword evidence="1" id="KW-1043">Host membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-1188">Viral release from host cell</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="topological domain" description="Periplasmic" evidence="1">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AVJ51926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="67" mass="7284" checksum="974F1A3B34B95134" modified="2018-05-23" version="1">MLTLDFNNEVIKAAPIAGVAGADGVARLFWGLSLNEWFYVAAIAYTVVQIGAKVVDKVIDWKKASKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL05</accession>
    <name>A0A2P1CL05_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_7</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="79" mass="9089" checksum="C076D6A95FD38A89" modified="2018-05-23" version="1">MALDVMFFENRLNKLAAYANSIGLRLRWMNEPMTLSLRVGIFELGSQEPLAEKTFEWGASSLDVERWVATVCKDYASWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL09</accession>
    <name>A0A2P1CL09_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_6</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013232">
        <property type="entry name" value="Phage_T7_Gp1.1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08200">
        <property type="entry name" value="Phage_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AVJ51889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="40" mass="5003" checksum="429F1A3B720CCE36" modified="2018-05-23" version="1">MRNFEKFTKRSSRKDFAEFAQEGRKMNKVKRDRSHKRNWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL12</accession>
    <name>A0A2P1CL12_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HNHc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_9</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51892.2"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13392">
        <property type="entry name" value="HNH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="60"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AVJ51892.2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="154" mass="17190" checksum="32146FE9A58D5607" modified="2018-07-18" version="2">MAHCVTRLSVASEELRTIQQRRYKLDPAAPSGVASSKGKPIGSRRKDGYWVLSCGGKHILAHRVVWVLHNGPIPDGLVIDHINRNPSDNRIENLRCVPQSVNLANVSVRPHCKSGEKYIAFDSRTGRFTVRIRRVNHGTFATLEEAIAKRDSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL13</accession>
    <name>A0A2P1CL13_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Endolysin</fullName>
            <ecNumber evidence="4">3.5.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">N-acetylmuramoyl-L-alanine amidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ebrios_17</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Endolysin with amidase activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and breaking down the peptidoglycan layer.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Plays an important role in the switch between viral transcription and genome replication. Once produced in sufficient amount, interacts with and inhibits the viral RNA polymerase that becomes unable to produce additional late transcripts. This lysozyme-polymerase complex in turn plays an active role in viral genome replication and packaging.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.</text>
            <dbReference type="EC" id="3.5.1.28"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Zn(2+) is required for amidase activity.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="4">Binding to the viral RNA polymerase inhibits amidase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with the viral RNA polymerase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Host cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">The endolysin is cytoplasmic, but can reach the periplasmic space with the help of the holins which disrupt the host cell membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.28" evidence="4"/>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030430">
        <property type="term" value="C:host cell cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032897">
        <property type="term" value="P:negative regulation of viral transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044659">
        <property type="term" value="P:viral release from host cell by cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04111">
        <property type="entry name" value="ENDOLYSIN_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034689">
        <property type="entry name" value="Endolysin_T7_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015510">
        <property type="entry name" value="PGRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006619">
        <property type="entry name" value="PGRP_domain_met/bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11022">
        <property type="entry name" value="PTHR11022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00701">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="3 4" id="KW-0081">Bacteriolytic enzyme</keyword>
    <keyword evidence="4" id="KW-0204">Cytolysis</keyword>
    <keyword evidence="4" id="KW-0578">Host cell lysis by virus</keyword>
    <keyword evidence="4" id="KW-1035">Host cytoplasm</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0426">Late protein</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1188">Viral release from host cell</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="PGRP" evidence="6">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="site" description="Essential for amidase activity and zinc hydrate coordination" evidence="4">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AVJ51900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="151" mass="17110" checksum="058FB5DFD9AF7012" modified="2018-05-23" version="1">MSRVQFKQREATNAIFVHCSATKATQDVGVREIRQWHKEQGWLDVGYHFIIRRDGTVEDGRDVNAVGSHARGHNHNSVGVCLVGGIDEKGRHEANFTPQQMSSLRTLLEVLMDKYPSAVLKAHHDVAPKACPSFDLQRWWKHNELVTSDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL15</accession>
    <name>A0A2P1CL15_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_16</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008833">
        <property type="term" value="F:deoxyribonuclease IV (phage-T4-induced) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016032">
        <property type="term" value="P:viral process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008029">
        <property type="entry name" value="Phage_T7_Gp3_endoDNaseI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05367">
        <property type="entry name" value="Phage_endo_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="151" mass="17445" checksum="BDD42E45315C6CB0" modified="2018-05-23" version="1">MAGAYAARGIRKVGAFRSGLEDNVSKQLEIKGVKFDYELWKIPYVVPASNHWYTPDFLLPNGIFIETKGLWESDDRKKHLLIREQFPELDIRLVFSSSRTKLYKGSPTSYGEWCEKHGILFADKLIPVEWLKEPKKEVPFDKLKQSKGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL18</accession>
    <name>A0A2P1CL18_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_27</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="304" mass="34594" checksum="F5F5D8939640D54B" modified="2018-05-23" version="1">MAVLSLKEFRDIREGCDDKGILVMDGDWLVFQAMSAAEFDASWEEEIWHRCCDHAKARQILDDSIKSYSTRKKAWNGAPIVLSFTDTINWRKELVDPTYKENRKATKKPVGYFEFLDALFERHEFYCVREDMLEGDDVMGIIGSNPSAFGARKAVIISCDKDFKTIPDCDFLWCTTGNILTQTQESADWWHLFQTIKGDITDGYSGIAGWGDSAEGFLNDPFITEPQVSVLKSGKNKGQEVTKWVKRAPTESETLWDCIVSIGAKAGMTEEDVIKQGQMARILRFNDYNIDTKEITLWRPSASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL19</accession>
    <name>A0A2P1CL19_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA helicase/primase</fullName>
            <ecNumber evidence="1">2.7.7.-</ecNumber>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gene product 4</fullName>
            <shortName evidence="1">Gp4</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">4</name>
        <name evidence="5" type="ORF">ebrios_19</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-dependent DNA helicase and primase essential for viral DNA replication and recombination. The helicase moves 5' -&gt; 3' on the lagging strand template, unwinding the DNA duplex ahead of the leading strand polymerase at the replication fork and generating ssDNA for both leading and lagging strand synthesis. ATP or dTTP hydrolysis propels each helicase domain to translocate 2 nt per step sequentially along DNA. Mediates strand transfer when a joint molecule is available and participates in recombinational DNA repair through its role in strand exchange. Primase activity synthesizes short RNA primers at the sequence 5'-GTC-3' on the lagging strand that the polymerase elongates using dNTPs and providing the primase is still present.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 2 Mg(2+), one of which is catalytic.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer. Assembles as a hexamer onto linear or circular ssDNA in the presence of ATP or dTTP. Interacts (via C-terminus) with the viral DNA polymerase that is bound to DNA; this interaction is essential to initiate leading-strand DNA synthesis. The priming complex consists of 2 DNA polymerases and 1 helicase-primase hexamer that assemble on the DNA template. Interacts with the single-stranded DNA-binding protein. Part of the replicase complex that includes the DNA polymerase, thioredoxin, the primase/helicase and the single-stranded DNA binding protein.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The N-terminus zinc finger domain is essential for delivering the primed DNA template to the DNA polymerase. The central core domain contains the primase activity. The C-terminus region is responsible for the helicase activity and binds 1 Mg(2+)-dTTP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Teseptimavirus DNA helicase/primase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="1"/>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01029">
        <property type="entry name" value="TOPRIM_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04154">
        <property type="entry name" value="Helic_Prim_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046394">
        <property type="entry name" value="Helic_Prim_T7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013237">
        <property type="entry name" value="Phage_T7_Gp4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034154">
        <property type="entry name" value="TOPRIM_DnaG/twinkle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027032">
        <property type="entry name" value="Twinkle-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12873">
        <property type="entry name" value="PTHR12873"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00778">
        <property type="entry name" value="Prim_Zn_Ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1 5" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="1" id="KW-0639">Primosome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-1194">Viral DNA replication</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="3">
        <location>
            <begin position="149"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="SF4 helicase" evidence="4">
        <location>
            <begin position="279"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-like; zinc ribbon fold" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="541"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="310"/>
            <end position="317"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="dTTP/dATP binding" evidence="1">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <feature type="site" description="dTTP/dATP binding" evidence="1">
        <location>
            <position position="463"/>
        </location>
    </feature>
    <feature type="site" description="dTTP/dATP binding" evidence="1">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <feature type="site" description="dTTP/dATP binding" evidence="1">
        <location>
            <position position="520"/>
        </location>
    </feature>
    <feature type="site" description="dTTP/dATP binding" evidence="1">
        <location>
            <position position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AVJ51902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="566" mass="62338" checksum="6EFC380E54033226" modified="2018-05-23" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL23</accession>
    <name>A0A2P1CL23_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_26</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="16"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AVJ51909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="76" mass="8743" checksum="8607520D58EDF5CB" modified="2018-05-23" version="1">MSIRKCWNDEVVSMTAEAWNETLKNIKELEDRIEELEQILADHEEDVAFLDALRSAGVDNWDGYDVACEIHKGEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL25</accession>
    <name>A0A2P1CL25_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2 7">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ebrios_5</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the phage and mitochondrial RNA polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 7"/>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019083">
        <property type="term" value="P:viral transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024075">
        <property type="entry name" value="DNA-dir_RNA_pol_helix_hairp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002092">
        <property type="entry name" value="DNA-dir_Rpol_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037159">
        <property type="entry name" value="RNA_POL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029262">
        <property type="entry name" value="RPOL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102">
        <property type="entry name" value="PTHR10102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00940">
        <property type="entry name" value="RNA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14700">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01311">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00900">
        <property type="entry name" value="RNA_POL_PHAGE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00489">
        <property type="entry name" value="RNA_POL_PHAGE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-1195">Viral transcription</keyword>
    <feature type="domain" description="RPOL_N" evidence="8">
        <location>
            <begin position="34"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AVJ51888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="883" mass="98754" checksum="0004EABB2FEA37EA" modified="2018-05-23" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL26</accession>
    <name>A0A2P1CL26_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_29</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020134">
        <property type="entry name" value="Phage_T7-like_6.7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17570">
        <property type="entry name" value="DUF5476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AVJ51912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="83" mass="8811" checksum="C1973D3E998A4C05" modified="2018-05-23" version="1">MCFSPKIKVPQMNVEKAPEPAPLTELPTGVEFGGDTPTDGTEEESGRKALKVERKETSMTKPKSGPSGSMKSTIRKSAFGGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL28</accession>
    <name>A0A2P1CL28_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tail fiber protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_37</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="793" mass="88699" checksum="A3627E62BBEFA36F" modified="2018-05-23" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL29</accession>
    <name>A0A2P1CL29_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tail fiber protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_36</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033767">
        <property type="entry name" value="Tail_Gp11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17212">
        <property type="entry name" value="Tube"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="196" mass="22328" checksum="7FCB021DD3B98806" modified="2018-05-23" version="1">MRSYDMSVETAAELAAVNDILAAIGEPPVSTLEGDSNADVANARRILNKINRQVQSQGWTFNIEEGVMLLPDVFSNLITYSDDYLSIMSPSGQSTYVNRGGYVYDRTNRTDRFTEAITVNLIRLREFDEMPECFRYWIVTKASRQFNNRFFGAPEVEGVLQEEEDEARRLCMEYEMDYGGYNMLDGDAFTSGLLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL34</accession>
    <name>A0A2P1CL34_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="1">SSB protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">2.5 protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Gene product 2.5</fullName>
            <shortName evidence="1">gp2.5</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ebrios_15</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advances and stimulates the activities of viral DNA polymerase and primase/helicase. Coordinates simultaneous synthesis of leading- and lagging-strands. Together with DNA primase/helicase, promotes pairing of two homologous DNA molecules containing complementary single-stranded regions and mediates homologous DNA strand exchange. Promotes also the formation of joint molecules. Disrupts loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Interacts (via C-terminus) with the viral DNA polymerase. Interacts with the viral helicase/primase. Part of the replicase complex that includes the DNA polymerase, host thioredoxin, the primase/helicase and the single-stranded DNA binding protein.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The acidic C-terminus is involved in modulating the ssDNA binding properties. It is also required for dimer formation and for interactions with the viral DNA polymerase and the helicase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Teseptimavirus single-stranded DNA-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04153">
        <property type="entry name" value="SSB_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016411">
        <property type="entry name" value="SSB_T7"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004311">
        <property type="entry name" value="Helix_destablz_SSB_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1194">Viral DNA replication</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="188"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AVJ51898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="230" mass="25464" checksum="F5C401873ECF8D4A" modified="2018-05-23" version="1">MAKKIFTSALGTAEPYAYLAKPDYGNEERGFGNPRGVYKVDLTIPNKDPRCQRMVDEIVKCHEEAYAAAVEEYEANPPAVARGKKPLQPYEGDMPFFDNGDGTTTFKFKCYASFQDKKTKETKHINLVVVDSKGKKMEEVPIIGGGSKLKVKYSLVPYKWNTAVGASVKLQLESVMLVELATFGGGEDDWADEVEEGGYVASGSARSKPRDEEDWSEDTEEESAGDDEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL36</accession>
    <name>A0A2P1CL36_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Internal virion protein gp14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ebrios_39</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the cylindrical core that assembles on the inner surface of the capsid during capsid formation and plays a role in viral DNA ejection into the host cell. The inner core is composed of stacked rings of gp14, gp15 and gp16 proteins. Following binding to the host cell surface, the internal core is disassembled and gp14 is ejected along with gp15 and gp16 into the infected cell. May form a simple channel spanning the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with the portal protein. Interacts with gp15.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Host cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the T7virus internal virion protein gp14 family.</text>
    </comment>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020002">
        <property type="term" value="C:host cell plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044423">
        <property type="term" value="C:virion component"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099002">
        <property type="term" value="P:viral genome ejection through host cell envelope, short tail mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04118">
        <property type="entry name" value="GP14_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038996">
        <property type="entry name" value="Gp14"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1033">Host cell outer membrane</keyword>
    <keyword evidence="1" id="KW-1043">Host membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1171">Viral genome ejection through host cell envelope</keyword>
    <keyword evidence="1" id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword evidence="1" id="KW-1244">Viral short tail ejection system</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <keyword evidence="1" id="KW-1160">Virus entry into host cell</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AVJ51922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="196" mass="20865" checksum="96F270305A1DEE52" modified="2018-05-23" version="1">MCWMAAIPIAMAGAQAVSGQATEANVLGAQINAGRRQAMELLKQTNIQNADLTLQAKSNLEEASAELSTQNMQKVQAMGAIRAAIGESNLEGRSMERIQRVTEGQFIREANMVTENYRRNYQAIFAQQIGAHQSTVSQIQEIYKGEPKGKSKLQQILDPLAVVGGQTASAYASGAFDGPAFGGKSSSKSTAKGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL37</accession>
    <name>A0A2P1CL37_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_47</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="50" mass="5455" checksum="62EB3C2E72BFE15B" modified="2018-05-23" version="1">MFRFVLTLLKHRVTYRFLVVLVAALGCASTIGDTIGTLESYVCAVLSCSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL38</accession>
    <name>A0A2P1CL38_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Terminase, large subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">DNA-packaging protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="1">ATPase</fullName>
                <ecNumber evidence="1">3.6.4.-</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">Endonuclease</fullName>
                <ecNumber evidence="1">3.1.21.-</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_46</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">The terminase large subunit acts as an ATP driven molecular motor necessary for viral DNA translocation into empty capsids and as an endonuclease that cuts the viral genome at a unique and precise dsDNA sequence to initiate and to end a packaging reaction. The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit involved in viral DNA recognition (packaging sequence), and a large terminase subunit possessing endonucleolytic and ATPase activities. Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine. The terminase large subunit exhibits endonuclease activity and cleaves the viral genome concatemer. Once the DNA is packaged, the terminase detaches from the portal and gets replaced by the tail to finish maturation of the virion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homopentamer. Interacts with the terminase small subunit; the active complex is probably heterooligomeric. Interacts with the portal protein.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The ATPase region is in the N-terminus, whereas the nuclease region is in the central part. The C-terminus is involved in prohead binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Teseptimavirus large terminase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="1"/>
    <dbReference type="EC" id="3.1.21.-" evidence="1"/>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098009">
        <property type="term" value="C:viral terminase, large subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019073">
        <property type="term" value="P:viral DNA genome packaging"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04147">
        <property type="entry name" value="TERL_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044271">
        <property type="entry name" value="Terminase_large_su_gp19"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0231">Viral genome packaging</keyword>
    <keyword evidence="1" id="KW-1188">Viral release from host cell</keyword>
    <feature type="region of interest" description="Nuclease activity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in prohead binding" evidence="1">
        <location>
            <begin position="571"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Walker A motif" evidence="1">
        <location>
            <begin position="58"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Walker B motif" evidence="1">
        <location>
            <begin position="156"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic; for nuclease activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="518"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic; for nuclease activity</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AVJ51929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="586" mass="66291" checksum="E0E9CC307255B3EF" modified="2018-05-23" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL40</accession>
    <name>A0A2P1CL40_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_11</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="88" mass="10372" checksum="772554A1A34FEBB0" modified="2018-05-23" version="1">MKFKLHYHKLFKHFTVRRSDTRAIVFTTERRFAIPLIGQTVELAPKVHVIITRGKFQEATNKTRPVLNVAVTRFPFVKLLIERVKEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL42</accession>
    <name>A0A2P1CL42_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HNS binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_25</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="69" mass="7385" checksum="88EAD448E94E565C" modified="2018-05-23" version="1">MSDYIKVLQAIKGCPKSFQSNYVRNNASLVAEAASRGHISCLTTGGRNAGVWEITAYGVQFLDEMGGCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL49</accession>
    <name>A0A2P1CL49_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_21</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035151">
        <property type="entry name" value="TA_inhibitor"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17574">
        <property type="entry name" value="TA_inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="90" mass="10310" checksum="5D484FA48331AFEA" modified="2018-05-23" version="1">MSKVSQTIALSDTIDQWGRKVHINVRNGKATMVYRWKDTKSNKKHTQRMTLNDEQAFRLLKALTGAVVHAVETSGRQEQAMEILNRIEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL50</accession>
    <name>A0A2P1CL50_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Capsid and scaffold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_35</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AVJ51918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="52" mass="5349" checksum="F80342482C008FB9" modified="2018-05-23" version="1">MLGEASTVAASTEEVSVTSTEETLTPAQKAARTRAANKARKEAELAAATAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL55</accession>
    <name>A0A2P1CL55_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Host range protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_31</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024281">
        <property type="entry name" value="Phage_T7-like_viron_assmbl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11653">
        <property type="entry name" value="VirionAssem_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AVJ51914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="100" mass="10312" checksum="0AC1F49D1FD29147" modified="2018-05-23" version="1">MGKKITKAVKKVVREVARPVKQAAKEITRPIKQVAGALAGTPDMPEIAPPTPSAALVEVPQQEEAQTDTDADTAASRKKARAGGKKSLSVARSAGGGINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL58</accession>
    <name>A0A2P1CL58_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">I-spanin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_45</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016417">
        <property type="entry name" value="I-spanin_T7likevirus"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004485">
        <property type="entry name" value="T7_18-5_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="145" mass="16527" checksum="921F70AF15AAFF95" modified="2018-05-23" version="1">MGLLKKLIPWVFAGMLFGTGWHLGADSMDTKWKQEVHREYVKKTEARAATQAEVDKISQGYQQKLSTLEGDTDRLVTGLRSDNKRLRVRIKQLSETPNGDSGCFPDGRAELDERDAKRILAVTQKADAWIRALQETIRKLQEQNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CL61</accession>
    <name>A0A2P1CL61_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Internal virion protein D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_41</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039678">
        <property type="term" value="P:viral genome ejection through host cell envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04121">
        <property type="entry name" value="TRANSGLYCOSYLASE_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038994">
        <property type="entry name" value="Gp16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000189">
        <property type="entry name" value="Transglyc_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00922">
        <property type="entry name" value="TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLT" evidence="1">
        <location>
            <begin position="15"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AVJ51924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="1321" mass="143349" checksum="FFFAA6442BAE3BAC" modified="2018-05-23" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CLE0</accession>
    <name>A0A2P1CLE0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_2</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="45" mass="5268" checksum="F1A1666896DAD8AB" modified="2018-05-23" version="1">MLKHYVMPIRHSTGATVCTPDGFAMKARIERLKRELRTNRKLNNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CLE3</accession>
    <name>A0A2P1CLE3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_12</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021739">
        <property type="entry name" value="SaV-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11753">
        <property type="entry name" value="DUF3310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="118" mass="13458" checksum="6631BA6E2598D356" modified="2018-05-23" version="1">MGHYDCHKCGEYLCLGDCDVPVVVNEKAVAVGPSKQAPKQIEGVQKPSHYYLFDDIEVIEVIARSMTREQFKGYVLGNILKYRLRAGKKGELAYLEKDMAKAEFYETLYEQHKGKCYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CLF0</accession>
    <name>A0A2P1CLF0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_22</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AVJ51905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="142" mass="15898" checksum="F0B2E88E5D3545DA" modified="2018-05-23" version="1">MRSQFVIEAEIAKLQAELEDVKAHESKVIAAAHILTNLGWTWTRKDGWKKPVAPIKPTVFDKDTMTHIKKGDFCLYAKGTVLEGFVLVREVNGAECTVSYVSSIAEFNRPVVATLKFRCHANMLKVVSSQTLVDCMKNNMVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CLF3</accession>
    <name>A0A2P1CLF3_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Portal protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Head-to-tail connector</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ebrios_32</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 9">Forms the portal vertex of the capsid. This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection. The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homododecamer. Interacts with major capsid protein. Interacts with the tail tube protein gp11. Interacts with the terminase large subunit. Interacts with the internal virion protein gp14.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Virion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the podoviridae portal protein family.</text>
    </comment>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046798">
        <property type="term" value="C:viral portal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019073">
        <property type="term" value="P:viral DNA genome packaging"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099002">
        <property type="term" value="P:viral genome ejection through host cell envelope, short tail mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04120">
        <property type="entry name" value="PORTAL_PROTEIN_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020991">
        <property type="entry name" value="Connector_podovirus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038995">
        <property type="entry name" value="Portal_prot_Caudovirale"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12236">
        <property type="entry name" value="Head-tail_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0118">Viral capsid assembly</keyword>
    <keyword evidence="9" id="KW-1171">Viral genome ejection through host cell envelope</keyword>
    <keyword evidence="7 9" id="KW-0231">Viral genome packaging</keyword>
    <keyword evidence="9" id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-1188">Viral release from host cell</keyword>
    <keyword evidence="3 9" id="KW-1244">Viral short tail ejection system</keyword>
    <keyword evidence="5 9" id="KW-0946">Virion</keyword>
    <keyword evidence="8 9" id="KW-1160">Virus entry into host cell</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AVJ51915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="536" mass="58889" checksum="6D4574B1483ABFF0" modified="2018-05-23" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-05-23" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2P1CLG0</accession>
    <name>A0A2P1CLG0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tail fiber protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_42</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AVJ51925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005604">
        <property type="entry name" value="Phage_T7_tail_fibre"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037053">
        <property type="entry name" value="Phage_tail_collar_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03906">
        <property type="entry name" value="Phage_T7_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AVJ51925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="651" mass="69509" checksum="9B8CEDE2BB11818F" modified="2018-05-23" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S2HFF7</accession>
    <name>A0A2S2HFF7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_19A</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AWL54347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AWL54347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="38" mass="4152" checksum="49216DD305EA2DF7" modified="2018-07-18" version="1">MRVQGTLTTTSTASCVVATRREMVRSQSVPVTNREANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S2HFG5</accession>
    <name>A0A2S2HFG5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">S-adenosyl-L-methionine hydrolase, phage-associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_1</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AWL54346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AWL54346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="151" mass="17109" checksum="2D46614E20BC7E5C" modified="2018-07-18" version="1">MIFTKEPANVFYVLVSAFRSNLDDAENMSRHRHMVSTLRAAEGLYGSIESTDLTGCYREEIASAPTEEKTVRVRCKDKVQALNVARLACNEWEQDCVLVYNSQTHTASLMYAKGLDGYKTERLGSFQEVPKGAPLQGCYTIDEFGRRWQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S2HFG7</accession>
    <name>A0A2S2HFG7_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA helicase/primase</fullName>
            <ecNumber evidence="1">2.7.7.-</ecNumber>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gene product 4</fullName>
            <shortName evidence="1">Gp4</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">4</name>
        <name evidence="5" type="ORF">ebrios_19B</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-dependent DNA helicase and primase essential for viral DNA replication and recombination. The helicase moves 5' -&gt; 3' on the lagging strand template, unwinding the DNA duplex ahead of the leading strand polymerase at the replication fork and generating ssDNA for both leading and lagging strand synthesis. ATP or dTTP hydrolysis propels each helicase domain to translocate 2 nt per step sequentially along DNA. Mediates strand transfer when a joint molecule is available and participates in recombinational DNA repair through its role in strand exchange. Primase activity synthesizes short RNA primers at the sequence 5'-GTC-3' on the lagging strand that the polymerase elongates using dNTPs and providing the primase is still present.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 2 Mg(2+), one of which is catalytic.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer. Assembles as a hexamer onto linear or circular ssDNA in the presence of ATP or dTTP. Interacts (via C-terminus) with the viral DNA polymerase that is bound to DNA; this interaction is essential to initiate leading-strand DNA synthesis. The priming complex consists of 2 DNA polymerases and 1 helicase-primase hexamer that assemble on the DNA template. Interacts with the single-stranded DNA-binding protein. Part of the replicase complex that includes the DNA polymerase, thioredoxin, the primase/helicase and the single-stranded DNA binding protein.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The central core domain contains the primase activity. The C-terminus is responsible for the helicase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Teseptimavirus DNA helicase/primase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="1"/>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AWL54348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01029">
        <property type="entry name" value="TOPRIM_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04154">
        <property type="entry name" value="Helic_Prim_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046394">
        <property type="entry name" value="Helic_Prim_T7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034154">
        <property type="entry name" value="TOPRIM_DnaG/twinkle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027032">
        <property type="entry name" value="Twinkle-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12873">
        <property type="entry name" value="PTHR12873"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1 5" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="1" id="KW-0639">Primosome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-1194">Viral DNA replication</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="3">
        <location>
            <begin position="88"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="SF4 helicase" evidence="4">
        <location>
            <begin position="218"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="480"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="249"/>
            <end position="256"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="dTTP/dATP binding" evidence="1">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <feature type="site" description="dTTP/dATP binding" evidence="1">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <feature type="site" description="dTTP/dATP binding" evidence="1">
        <location>
            <position position="441"/>
        </location>
    </feature>
    <feature type="site" description="dTTP/dATP binding" evidence="1">
        <location>
            <position position="459"/>
        </location>
    </feature>
    <feature type="site" description="dTTP/dATP binding" evidence="1">
        <location>
            <position position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AWL54348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="505" mass="55528" checksum="77D218E6E10A6B90" modified="2018-07-18" version="1">MSYDVWNFGESQGKYSALTARGISKETCQKAGYWIAKVNGVCYQVADYRDQNGSIISQKVRDKDKNFKTTGSHKSDALFGKHLWNGGKKIVVTEGEIDMLTVMELQDCKYPVVSLGHGASAAKKTCAANYEYFDQFEQIILMFDMDEAGRKAVEEAAQVLPAGKVRVAVLPCKDANECHMLGEDRAVLEQIWNAGPWIPDGVVSALSLRERIREHLGSEDAVGILFSGCSGLNDRTLGARGGEIIMVTSGSGMGKSTFVRQQALMWGKAMGKRVGLAMLEESVEETAEDLIGLNNYVRLRQSDDLKNAIIEDGRFDQWFDELFGNDTFHLYDSFAEAEADRLLAKLAYMRTGLGCDVIVLDHISIVVSASEESDERKMIDRLMTKLKGFAKSTGVVLVVICHLKNPEKGKAHEEGRPVSITDLRGSGALRQLSDTIIALERNQQGDAPNLVLVRVLKCRFTGDTGIAGYMEYNKKTGWLEPSSYSGEEGEGDTGWEGEASGSSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S2HFI7</accession>
    <name>A0A2S2HFI7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_46B</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AWL54352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035178">
        <property type="entry name" value="DUF5466"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17554">
        <property type="entry name" value="DUF5466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AWL54352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="57" mass="6405" checksum="12C3537DB9FEDEF2" modified="2018-07-18" version="1">MVTLIRRSNCSLRRPSSGKSRLWSSRVTSVTVCSVRCSLRFSLSTTTLSLRKSVREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S2HFJ4</accession>
    <name>A0A2S2HFJ4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ebrios_19C</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AWL54349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035148">
        <property type="entry name" value="DUF5480"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17576">
        <property type="entry name" value="DUF5480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AWL54349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="98" mass="10578" checksum="FB8FC7DF0FC0BDE1" modified="2018-07-18" version="1">MKKVALFLLLTSVVLGHYVNSLTLLLPLSATSKVTLLILSSCVFSSAALLAILVLLATWNTTRKPDGSNRLATLARKEKEILAGKAKRQAAQTFNTTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S2HFK2</accession>
    <name>A0A2S2HFK2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_46A</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AWL54351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020148">
        <property type="entry name" value="DUF5477"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17571">
        <property type="entry name" value="DUF5477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AWL54351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="55" mass="5838" checksum="54B9D0C625F54893" modified="2018-07-18" version="1">MATPPSSGLPCTRGAVKKTCTTHSVSHRCSERSTTRTLRPCLVHLPTLCASIGKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-07-18" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2S2HFV6</accession>
    <name>A0A2S2HFV6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">O-spanin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ebrios_45A</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage Ebrios</name>
        <dbReference type="NCBI Taxonomy" id="2099356"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Autographiviridae</taxon>
            <taxon>Studiervirinae</taxon>
            <taxon>Teseptimavirus</taxon>
            <taxon>Escherichia virus Ebrios</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-02" db="EMBL/GenBank/DDBJ databases">
            <title>Complete Genome Sequence of Ebrios, a novel T7-like phage isolated from the Lagoon Ebrie in Abidjan.</title>
            <authorList>
                <person name="Ngazoa-Kakou S."/>
                <person name="Philippe C."/>
                <person name="Tremblay D.M."/>
                <person name="Loignon S."/>
                <person name="Koudou A."/>
                <person name="Abole A."/>
                <person name="Coulibaly D.N."/>
                <person name="Kan Kouassi S."/>
                <person name="Kouame-Sina M."/>
                <person name="Aoussi S."/>
                <person name="Dosso M."/>
                <person name="Moineau S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="MG966531">
        <property type="protein sequence ID" value="AWL54350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000240985">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019076">
        <property type="term" value="P:viral release from host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020130">
        <property type="entry name" value="O-spanin_T7likevirus"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17531">
        <property type="entry name" value="O_Spanin_T7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AWL54350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000240985"/>
        </source>
    </evidence>
    <sequence length="84" mass="9147" checksum="242C8557A3E54D7A" modified="2018-07-18" version="1">MSTLRKPRQELPLKQKSIRLAKDTSKSCPLWRATLIGLLLACVATISGCVSASSNLVKPQMVTVDASLMVEPNLTNEMLSVFSQ</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>