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        <name type="scientific">Pteromalus puparum negative-strand RNA virus 1</name>
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            <title>A Novel Negative-stranded RNA Virus Mediates Sex Ratio in Its Parasitoid Host.</title>
            <authorList>
                <person name="Wang F."/>
                <person name="Fang Q."/>
                <person name="Wang B."/>
                <person name="Yan Z."/>
                <person name="Hong J."/>
                <person name="Bao Y."/>
                <person name="Kuhu J.H."/>
                <person name="Werren J.H."/>
                <person name="Song Q."/>
                <person name="Ye G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1">1</strain>
        </source>
    </reference>
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    <reference evidence="2 3" key="1">
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            <title>A Novel Negative-stranded RNA Virus Mediates Sex Ratio in Its Parasitoid Host.</title>
            <authorList>
                <person name="Wang F."/>
                <person name="Fang Q."/>
                <person name="Wang B."/>
                <person name="Yan Z."/>
                <person name="Hong J."/>
                <person name="Bao Y."/>
                <person name="Kuhu J.H."/>
                <person name="Werren J.H."/>
                <person name="Song Q."/>
                <person name="Ye G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">1</strain>
        </source>
    </reference>
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            <dbReference type="EMBL" id="APL97664.1"/>
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    </evidence>
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            <taxon>Negarnaviricota</taxon>
            <taxon>Haploviricotina</taxon>
            <taxon>Monjiviricetes</taxon>
            <taxon>Mononegavirales</taxon>
            <taxon>Artoviridae</taxon>
            <taxon>Peropuvirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-06" db="EMBL/GenBank/DDBJ databases">
            <title>A Novel Negative-stranded RNA Virus Mediates Sex Ratio in Its Parasitoid Host.</title>
            <authorList>
                <person name="Wang F."/>
                <person name="Fang Q."/>
                <person name="Wang B."/>
                <person name="Yan Z."/>
                <person name="Hong J."/>
                <person name="Bao Y."/>
                <person name="Kuhu J.H."/>
                <person name="Werren J.H."/>
                <person name="Song Q."/>
                <person name="Ye G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">1</strain>
        </source>
    </reference>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="EMBL" id="APL97665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000233833"/>
        </source>
    </evidence>
    <sequence length="402" mass="43497" checksum="1C1D9B78E9EB0AB3" modified="2017-03-15" version="1">MSGKKDAKTPRSATKGTLSKAEELLQQLAAYDPLTNNDPLSLGKKRPKPPKCPDIQEPSDSPPYKRHDTRGDEPDETRDPDPSLHPCYYPLGNSSSTASIVEVIESDSQDLNPPEEPKDRPSTRGETSRTATREQREVLSIRKLADTQEVISSDEEEEGRESGAVPKGFYTVPPPVLQYITGESSKKPGGFQTEMDRWFEDEWGKLVNPPPGLLSTHYLWCLPPSTTNTLAGEKFKVASNNLAISLGRSKIWGKKKSSKGTAGVLVLPFPGVQSNTAEKAAGDRLTKAAEALQQLAEDFKSAIAILQADINRQAAASRGFITDSSQSIRANTLSLIRSMEETAKSVKGTTTPVQGMGESRRDSRTTTPSLPGPGAGQSSRPSTGGLTIDPSKFKRIVPQGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-03-15" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1L5BWP9</accession>
    <name>A0A1L5BWP9_9MONO</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Replicase</fullName>
            <ecNumber evidence="19">2.1.1.375</ecNumber>
            <ecNumber evidence="5">2.7.7.48</ecNumber>
            <ecNumber evidence="6">2.7.7.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Transcriptase</fullName>
        </alternativeName>
    </protein>
    <organism evidence="24 25">
        <name type="scientific">Pteromalus puparum negative-strand RNA virus 1</name>
        <dbReference type="NCBI Taxonomy" id="1926633"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Negarnaviricota</taxon>
            <taxon>Haploviricotina</taxon>
            <taxon>Monjiviricetes</taxon>
            <taxon>Mononegavirales</taxon>
            <taxon>Artoviridae</taxon>
            <taxon>Peropuvirus</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2016-06" db="EMBL/GenBank/DDBJ databases">
            <title>A Novel Negative-stranded RNA Virus Mediates Sex Ratio in Its Parasitoid Host.</title>
            <authorList>
                <person name="Wang F."/>
                <person name="Fang Q."/>
                <person name="Wang B."/>
                <person name="Yan Z."/>
                <person name="Hong J."/>
                <person name="Bao Y."/>
                <person name="Kuhu J.H."/>
                <person name="Werren J.H."/>
                <person name="Song Q."/>
                <person name="Ye G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24">1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:65440"/>
            <dbReference type="Rhea" id="RHEA-COMP:16798"/>
            <dbReference type="Rhea" id="RHEA-COMP:16801"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156482"/>
            <dbReference type="ChEBI" id="CHEBI:156483"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + H(+) + 2 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:65376"/>
            <dbReference type="Rhea" id="RHEA-COMP:16797"/>
            <dbReference type="Rhea" id="RHEA-COMP:16798"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156483"/>
            <dbReference type="ChEBI" id="CHEBI:156484"/>
            <dbReference type="EC" id="2.1.1.375"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:65380"/>
            <dbReference type="Rhea" id="RHEA-COMP:16797"/>
            <dbReference type="Rhea" id="RHEA-COMP:16801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156482"/>
            <dbReference type="ChEBI" id="CHEBI:156484"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 5'-end triphospho-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + GDP + H(+) = a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:65436"/>
            <dbReference type="Rhea" id="RHEA-COMP:16797"/>
            <dbReference type="Rhea" id="RHEA-COMP:16799"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:156484"/>
            <dbReference type="ChEBI" id="CHEBI:156503"/>
            <dbReference type="EC" id="2.7.7.88"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Host cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Virion</location>
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    </comment>
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    <dbReference type="EC" id="2.7.7.48" evidence="5"/>
    <dbReference type="EC" id="2.7.7.88" evidence="6"/>
    <dbReference type="EMBL" id="KX431032">
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        <property type="molecule type" value="Viral_cRNA"/>
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        <property type="component" value="Genome"/>
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    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030430">
        <property type="term" value="C:host cell cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004482">
        <property type="term" value="F:mRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039530">
        <property type="entry name" value="L_methyltransferase_rhabdo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026890">
        <property type="entry name" value="Mononeg_mRNAcap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014023">
        <property type="entry name" value="Mononeg_RNA_pol_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025786">
        <property type="entry name" value="Mononega_L_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14314">
        <property type="entry name" value="Methyltrans_Mon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14318">
        <property type="entry name" value="Mononeg_mRNAcap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00946">
        <property type="entry name" value="Mononeg_RNA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50526">
        <property type="entry name" value="RDRP_SSRNA_NEG_NONSEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51590">
        <property type="entry name" value="SAM_MT_MNV_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-1035">Host cytoplasm</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="24" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="24" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="24" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0946">Virion</keyword>
    <feature type="domain" description="RdRp catalytic" evidence="22">
        <location>
            <begin position="559"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="domain" description="Mononegavirus-type SAM-dependent 2'-O-MTase" evidence="23">
        <location>
            <begin position="1608"/>
            <end position="1808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001270"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00024452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00024494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00024634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00026099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00030436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00031012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="APL97667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000233833"/>
        </source>
    </evidence>
    <sequence length="2166" mass="245855" checksum="A3AD6C15682A8B87" modified="2017-03-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-03-15" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1L5BWQ0</accession>
    <name>A0A1L5BWQ0_9MONO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative glycoprotein</fullName>
        </submittedName>
    </protein>
    <organism evidence="2 3">
        <name type="scientific">Pteromalus puparum negative-strand RNA virus 1</name>
        <dbReference type="NCBI Taxonomy" id="1926633"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Negarnaviricota</taxon>
            <taxon>Haploviricotina</taxon>
            <taxon>Monjiviricetes</taxon>
            <taxon>Mononegavirales</taxon>
            <taxon>Artoviridae</taxon>
            <taxon>Peropuvirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-06" db="EMBL/GenBank/DDBJ databases">
            <title>A Novel Negative-stranded RNA Virus Mediates Sex Ratio in Its Parasitoid Host.</title>
            <authorList>
                <person name="Wang F."/>
                <person name="Fang Q."/>
                <person name="Wang B."/>
                <person name="Yan Z."/>
                <person name="Hong J."/>
                <person name="Bao Y."/>
                <person name="Kuhu J.H."/>
                <person name="Werren J.H."/>
                <person name="Song Q."/>
                <person name="Ye G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX431032">
        <property type="protein sequence ID" value="APL97666.1"/>
        <property type="molecule type" value="Viral_cRNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000233833">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="516"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="APL97666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000233833"/>
        </source>
    </evidence>
    <sequence length="574" mass="63358" checksum="B0057CE2848D70E6" modified="2017-03-15" version="1"> </sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>