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<entry dataset="TrEMBL" created="2017-03-15" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1L3KMI1</accession>
    <name>A0A1L3KMI1_9VIRU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RdRp catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <organism evidence="6 7">
        <name type="scientific">Beihai blue swimmer crab virus 1</name>
        <dbReference type="NCBI Taxonomy" id="1922368"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>unclassified Riboviria</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Nature" volume="540" first="539" last="543">
            <title>Redefining the invertebrate RNA virosphere.</title>
            <authorList>
                <person name="Shi M."/>
                <person name="Lin X.D."/>
                <person name="Tian J.H."/>
                <person name="Chen L.J."/>
                <person name="Chen X."/>
                <person name="Li C.X."/>
                <person name="Qin X.C."/>
                <person name="Li J."/>
                <person name="Cao J.P."/>
                <person name="Eden J.S."/>
                <person name="Buchmann J."/>
                <person name="Wang W."/>
                <person name="Xu J."/>
                <person name="Holmes E.C."/>
                <person name="Zhang Y.Z."/>
            </authorList>
            <dbReference type="PubMed" id="27880757"/>
            <dbReference type="DOI" id=".1038/nature20167"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">YYSZX13554</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX884384">
        <property type="protein sequence ID" value="APG78597.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009333320.1">
        <property type="nucleotide sequence ID" value="NC_032488.1"/>
    </dbReference>
    <dbReference type="GeneID" id="30745578"/>
    <dbReference type="KEGG" id="vg:30745578"/>
    <dbReference type="Proteomes" id="UP000204501">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039694">
        <property type="term" value="P:viral RNA genome replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001370">
        <property type="entry name" value="BIR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001205">
        <property type="entry name" value="RNA-dir_pol_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007094">
        <property type="entry name" value="RNA-dir_pol_PSvirus"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00653">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00680">
        <property type="entry name" value="RdRP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50143">
        <property type="entry name" value="BIR_REPEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50507">
        <property type="entry name" value="RDRP_SSRNA_POS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0693">Viral RNA replication</keyword>
    <feature type="domain" description="RdRp catalytic" evidence="5">
        <location>
            <begin position="2573"/>
            <end position="2707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2877"/>
            <end position="2936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3719"/>
            <end position="3740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3923"/>
            <end position="3945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3957"/>
            <end position="3988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="2883"/>
            <end position="2904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="3957"/>
            <end position="3975"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="APG78597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000204501"/>
        </source>
    </evidence>
    <sequence length="3999" mass="448571" checksum="08A43F53B6D2A3DC" modified="2017-03-15" version="1">MRVPHNQIAQYYNEFAVPQIPQTSVQIEEIFDSPMETSPIATPALSAPVDLANQIEQAVEIYNEEFAKLTVSDLDPEFLPELTVEPNDFEAPKTPEPEAATSDLEWDDEPYINDPFASFPSWESFPTDNKLPTSYITEEELATVEKTPGVHHFMDSVTTQDPTTSAPITIWSHREITSYPDFVKLVVRQQTLKTIPYEQTKAFVLSQEHFPMSCQINNWTAAETYHEGSCYLAAFCEDAQQAFLLYSTESAPQFIVTDFYSRQESKNTSTEYCCYLKCKPAPMMVFGPLDCGCYNWCKCDCETVIRAKKLTPKKLISALSNIVTIMEEEEDQIEPGDIVHQSAQERYPDMPSAKEIQDAQLRVEGIADHAVCSECNLTLGHWQKGDDPLKDHRKWANDKCLGARLRDNKHIKKVAKDTRQPLNTQVVRIGHERRNLATFQNHLARIYARKRCRARQVAIEQLKKRIATFKQQKKVTEDWNIHTETYYTQTGLKSRQFSSPLRKLTFTPNAKTTQVFWSRDEWKTFAKLIVETESKVSEQMQEMGYPPVIRTEACSGDNNFIMEQCKSIIKKVTGITDKLICVAVGLVLASAVTSVIAAVKAENRTARWSSIASAVCSLVSVACLIVANSRLKKNATEAMDSIKNLVGKCTSTLHSAFSAKKPEEVVETPKEKLHFQYVDDFDNAKDKIWYVNQMDDMHWYSLQYYGETAPYVLNALAVLPSKEPTRLKHRKSWSWTEPPKYNQEEWTSYIVSLAEDAAPQAPSSVYSEEYGSEEDAEESILVRGATFLQTKNRLVTAPLSKDVEQKPGEVDEAQAIEKLSNTIASETYKAKAEAGLTHICTKKCWDKPGKGKVDWYPYTNILGLVAHLYVKSPPETPIREEKDLKHMGFRVTTVSEMSPRDTNCPNCILLCHSKDGSYVGLPTAYTAKKLQYGLNPPHFWPEYTSITAGHMTGTKLFDKNAISYIPYSVDMIPQLRNGEMHNDRCKRTYGTDSHTDEERGIYWNTKIGENAAVKHHTAEGRARFTAYPIKEAKNLRPLTKRTDAFADFDCGFIETEHGMVDVLPEEVKFSDSSSMIKLCTGVIATLGVGSYLGMSEKMDPIKACQLINQASTAKTNLDGAMNWIADVLLTSSEDESLSDIYKKIQRRYQILNAIPATYINVKPEFVYAIKRIQNEIVDFVKLMKNQKNSSEVSFYVRQCNLMTQELNRKFAEVVDGRENSGSRVPVLFVQLCGGKGLGKSTAVQAGGAIIRDINLMLGLDPETAPHQIIVDGGGFYNAYGGQAVGIRDEFLRQGDKDPFIEQVNALASPAAHGLSGAFVKQQPVAYRIVFLISNVMHVTIRDYVPEVRDAFWSRILRYRVSHEGIEKLVDDWGRHVVTDRDPRKWKWQRFTCNGDGEDRNETTIDYENFLHDVHRDILKLEYVNGSYRPLTELSRVIKEEVHTQMVNVQELTPNFKTRKFSQGRADDMPQDMRKKVTPNIAMSGHAHCVIHVHGKPGMGKTTFVKRQLANRWHTIDRDAKVYEMTSEFKIPADAKERDVYIVEDLLLAHQDAYHTFYQNLPGASVIIITSNIEVERPNWIYDALLSKIGTKRTYLNEIKAPGLLRRVGFSGQICNAEHSVDVVGTANFALEMTSRLNFKTQSGEDLSPIAAVARITQQVAQWADVFLEHPLKQVVDAIDENFNYDVVITAKNLDHLKNVLSSNTAILANLGMTPDHAIYLNPDVKDEFIESGNFSCAPWVLKEGHNRDEIAATLYSTLRQFRPQSTVKVVVGDYQAAVKSPGVMEVLLSANDYDVKFLKQDVKDTVVHFVSIKSANEEILLDMQKVETGILKGWTYVDLSAKEYEVVVANQRAIESIPEVSDIVLAKQAEREKQQKQAAKKAKMLYLKSIVYDHPILFSLACIALIGFMCSTITKAVKAVAGWWSSSSTELYKESGELIEAPLHGLACQKCKTKLVPEVRTVYLAQGPRQRLCSVMCSKCKTYVDLSPGMAKHVKAGMKIDNEIIHDQDLEWLRQKTNDRTQACGTISESTTEKRPKNMIYFPSGQVVSTDAPQWSDSLFACGDDNIDVVKNKIRQNFVKVSCCGSEVYGIGLAGKLVVTVAHIFFKNKAKPQVAYLEDGVERWVPATLVRQYTDRDIAFVTVDDKTKPQFKNIIRYVSTGADLDYVHDVALAHYKPNNSSDMYYTTAVFGDRIDLPIAELNVSDRGVMTATTLVALTTMKAIGRFAKKGRCGHPLLAFPNKDIQCRILCGLFNSSSKDAIDVTCSLLTREVVEDVIKHMHGKAQEHQLMGVLMPNKDAVYFTDYEVALFSKMYDNPCNDQVVSDNLTYIGSIPHGRNERVKLEPTIYHDIVAEARPLDVGIVPKVAPDVPEVVKDKKGKPCYYSTELSKIKSNDKQDDKIKKAVNEFVLKLYEDVYGTYYTLNTFKVLNGCENVSKARKSTAVGPSVKVVHPKADRKGYFYEERGQTTHWKETEEAQRMLEREMQILNLWYQGKPVLFVTEASIKEELLPKEKLAKGKARLFGAADQTCVNLEKRVMGGFIANAVETPANVVIGLDQQYDFHRMRRIFRTYPRVLNVDQKAFDKHTSNRDVKDALRIILNLNSTIEMRENRFQIIEAIAESLSKYIFVANGQCYHVTSGLNSGQYCTNIGGSTVSIVRGYYGVAKALMDEQQLDLEKAMLVLRRYFVMACGDDIVIMSNALQLPSAELVVHYMQDSGVTMQSPSKTGVNNYEWTMYPDTPIEFCGRNITEVEGYVVAPIRETAIYKGLYYTRDASRQNAILQLRVALEELYLHGDEKEYNKKRQLFQQCQKKTGIREHLPTWNEARLHFLEKHHGKGQVPLTAANSKETQDLLATRDLMIRRFMQNTYTRVACSGDNHQTAHQDNSEMERVDKKSETPKKEYMETPAARSAPRAQRTIQDAVQERAAQKHPELWTNKGPGIYHYEGPSVFLHDVSAGSFANSNFSPEPADYDVSDTGFTARLSQLAATGKKCDFYTQQLLKTILGTKTDKLWNLCLKAGVGLVATPVTPEPHEDELSAYHLRWQLVTASHTKFVFDGESWGTTSGDALRSAFTAILGAIIVDNHVSMKNRGNRTFREWFQRIACAGDNERTGGRDVSDSSAVPNSSDTFVSTNLQQDAGTFSLQGGMIPMDILKGGMHKNILDTIDQDFLIATKTISQTTAAGDNLLTLHLRDALYNHPFAKMMMQYSTKVSGYITFSIISTMSQLNQGGIIGYMVYPEGNSSGDLQVSGLIEKQLYQHDIRAVTQGISTRFTLPLCSQSAFFFWTEDFSETSDPELQPKFNVDAITAISNATTAAGDTAGLIYVHVNVSGLVFAGIKQTVLPPVGGTTLGTSTALTNHKDAINVNDVVGGIATLCLTGRSEMRENISSTDLYREYDEPRAANAVPAGLTPVSWGQVKYNSAPPLQNCIQKSTEVKLWNIADAEANEEIKMVVGRICTNKGSYDSGEVNPMLIASGTRTSKSKGSFTYLLRGGDGAMEILREDALSGLGPFYHGESSGSITEKYEARSLQWEWETPLVTVGQTYNIGEALPETWTNVTLRETCYHINTLGATNTNVGDDGQYKLFNYIKRKYDPTPGSIWAFSFLNKRYNQPVAQCVLYAAANLKDWRMYARVEETECVSTYEDSLIMSNPTQQSTSYVPPMTTTRNWVKSTYSSDTLSAKFMVREQVEKLGRIHSSKLDRVVRAQKVKSSVEKTLLREGEESPVVKKPPRKEKRSGRQLEACSGKSTHCPHDRLQIDCRDCGASSCAQCGRRLSRCTCRTVLKNRRLEACCLEWQEGCPHDYVTVDCTTCGASSCSQCGKRFSRCTCKRRCRELYACSLLGGAMSGMGNALNQRKQHKYDMENQDNWFRNAGNLSQQNFEQQQQLNMANYQNQKQLEMMRQSGSTTRADIAADATRYSARQSAGANVESTELQQQGANQRLASSQNFTREMKGIGQSNIMPSGTSSPKPPTGGASGEGSTGAVPKITRAAEDAAVVL</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>