<?xml version="1.0" encoding="UTF-8"?>
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<entry dataset="TrEMBL" created="2017-03-15" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1L3GZ65</accession>
    <name>A0A1L3GZ65_9VIRU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA-directed RNA polymerase</fullName>
            <ecNumber evidence="6">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <organism evidence="8 9">
        <name type="scientific">Saccharomyces kudriavzevii virus L-A1</name>
        <dbReference type="NCBI Taxonomy" id="1921825"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Duplornaviricota</taxon>
            <taxon>Chrymotiviricetes</taxon>
            <taxon>Ghabrivirales</taxon>
            <taxon>Totiviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2016" name="PLoS Pathog." volume="12" first="E1005890" last="E1005890">
            <title>XRN1 Is a Species-Specific Virus Restriction Factor in Yeasts.</title>
            <authorList>
                <person name="Rowley P.A."/>
                <person name="Ho B."/>
                <person name="Bushong S."/>
                <person name="Johnson A."/>
                <person name="Sawyer S.L."/>
            </authorList>
            <dbReference type="PubMed" id="27711183"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the totiviridae RNA-directed RNA polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="6"/>
    <dbReference type="EMBL" id="KX601068">
        <property type="protein sequence ID" value="APG32845.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009328931.1">
        <property type="nucleotide sequence ID" value="NC_032106.1"/>
    </dbReference>
    <dbReference type="GeneID" id="30522869"/>
    <dbReference type="KEGG" id="vg:30522869"/>
    <dbReference type="Proteomes" id="UP000204097">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015302">
        <property type="entry name" value="Major_coat_LA-virus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036332">
        <property type="entry name" value="Major_coat_LA-virus_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001795">
        <property type="entry name" value="RNA-dir_pol_luteovirus"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09220">
        <property type="entry name" value="LA-virus_coat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02123">
        <property type="entry name" value="RdRP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82856">
        <property type="entry name" value="SSF82856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0693">Viral RNA replication</keyword>
    <feature type="domain" description="LA-virus_coat" evidence="7">
        <location>
            <begin position="1"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="APG32845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000204097"/>
        </source>
    </evidence>
    <sequence length="1505" mass="170433" checksum="7ABFEB43DECEDE6C" modified="2017-03-15" version="1">MLRFVTKNSQDKSSDLFSICSDRGTFVAHNRVRTDFKFDNLVFNRVYGVSQKFTLVGNPTVCFNEGSSYLEGIAKKYLTLDGGLAIDNILNELKSTCGIPGNAVTSHAYNITSWRWYDNHVALLMNMLRAYHLQVLSEQGQYSAGAYPMYHDGHVKVKLDVAISEDAAPESFKWPGDRASDSFPEWAQFSESFPSIDVPYIDVRPLTVTEVNFVLMMMSKWHRRTNLAIDYAAPTLADKFAYRHAITVQDADEWIEGDRTDDQFRPPSSKVMLSALRKYVNHNRLYNQFYTAAQLLSQIMVKPVPNCAEGYAWLMHDALVNLPKFGSIRGRYPFLLAGDAALIQATALEDWSAIMAKPELVFTYAMQVAVALNTGLYLRRVKKTGFGTTIDDSYEDGPFLQPETFVQAALACCTGQDAPLNGMSDVYVTYPDLLELDALTRVPVTVLEPAGYNIVDGALEVVGVPIACSPYMIFPVAAFDKANPYSGNFVIQPAVKYLRKGALYDKLEAWKLAWAMRIAGYDTSFKVYGDVHGLTKFYADNSDSWTHIPEFVSDGDIMEVYVTAIERRTRHFVELPRLNSPAFFKSVEVSTTIYDTYVQAGTFSVYHASRINLDYVKPVSAGIQVINAGELRNYWGSVRRTQQGFRSGRSYDASSNAYRRTYSWCCPRRVDRTGGRCFSRVNIIEPSHGSKPSRYILTDPDTYPAWIRFRNRIQAVSRQKATHFLFDIVPASKLRSYTTGDIATFSYKSHTYATNVTAVKFADMYGLYVQVEANMTILSPAARRQASATYSQVTGFCFNSPTVMDTLVNILDVDRNIRPKHFKGLRDYERSKVTAQHHTHLRPDEVLEAAARVSPRRKYYLLCTAELLAACEVTIEAAVATIMAFVLTLDEKFVALFLDSRSIWLGPKGPDALTNRLKQASAQIKSVHTADYEPLTELFELAVLMNRGVGHVSWQTEREHREHPDVANVDQARLYSCVRDMFEGAKETYNYPYMSWDDYTASRWEWVPGGSVHSQYSEDDEYIFPGQFTRNKFITVNKMPKHKIARMIASAPEVRAWTSTKYEWGKQRAIYGTDLRSTLITNFAMFRCEDVLTHKFPVGDQAEAAKVHKRVNMMLDGASSFCFDYDDFNSQHSIASMYTVLVAFRDAFCRNMSAEQKEAMDWVCESVKHMWVLDPDSKEWYQLRGTLLSGWRLTTFMNTVLNWAYMQIAGVFDIDDVQDSVHNGDDVMISLNRVSTAVRIMDAMHKINARAQPAKCNLFSISEFLRVEHGMSGGDGLGAQYLSRSCATLVHSRIESNEPLSVVRVMEADQTRLKDLANRTSVKEAVTAITEQLKIRVTKIFSVDTSVVTQITRAHRVCGGISTDTWAPVDTKIQTDNEAYEIPYEIDDPSFWPGVNDYAYKVWQNFGERLEFNKIKDAVSKGSRNTIALKRKAKISAKKNPFIHKSEWERTMYKAYKGLAVSYYANLSKFMSIPPMANIEFGQARYAMQAALDSSDPLRALQIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-03-15" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1L3GZ72</accession>
    <name>A0A1L3GZ72_9VIRU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major coat protein</fullName>
        </submittedName>
    </protein>
    <organism evidence="2 3">
        <name type="scientific">Saccharomyces kudriavzevii virus L-A1</name>
        <dbReference type="NCBI Taxonomy" id="1921825"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Duplornaviricota</taxon>
            <taxon>Chrymotiviricetes</taxon>
            <taxon>Ghabrivirales</taxon>
            <taxon>Totiviridae</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2016" name="PLoS Pathog." volume="12" first="E1005890" last="E1005890">
            <title>XRN1 Is a Species-Specific Virus Restriction Factor in Yeasts.</title>
            <authorList>
                <person name="Rowley P.A."/>
                <person name="Ho B."/>
                <person name="Bushong S."/>
                <person name="Johnson A."/>
                <person name="Sawyer S.L."/>
            </authorList>
            <dbReference type="PubMed" id="27711183"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">1</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX601068">
        <property type="protein sequence ID" value="APG32846.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009328932.1">
        <property type="nucleotide sequence ID" value="NC_032106.1"/>
    </dbReference>
    <dbReference type="GeneID" id="30522868"/>
    <dbReference type="KEGG" id="vg:30522868"/>
    <dbReference type="Proteomes" id="UP000204097">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019028">
        <property type="term" value="C:viral capsid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015302">
        <property type="entry name" value="Major_coat_LA-virus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036332">
        <property type="entry name" value="Major_coat_LA-virus_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09220">
        <property type="entry name" value="LA-virus_coat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82856">
        <property type="entry name" value="SSF82856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0946">Virion</keyword>
    <feature type="domain" description="LA-virus_coat" evidence="1">
        <location>
            <begin position="1"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="APG32846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000204097"/>
        </source>
    </evidence>
    <sequence length="680" mass="75943" checksum="677B49C89A8312B1" modified="2017-03-15" version="1">MLRFVTKNSQDKSSDLFSICSDRGTFVAHNRVRTDFKFDNLVFNRVYGVSQKFTLVGNPTVCFNEGSSYLEGIAKKYLTLDGGLAIDNILNELKSTCGIPGNAVTSHAYNITSWRWYDNHVALLMNMLRAYHLQVLSEQGQYSAGAYPMYHDGHVKVKLDVAISEDAAPESFKWPGDRASDSFPEWAQFSESFPSIDVPYIDVRPLTVTEVNFVLMMMSKWHRRTNLAIDYAAPTLADKFAYRHAITVQDADEWIEGDRTDDQFRPPSSKVMLSALRKYVNHNRLYNQFYTAAQLLSQIMVKPVPNCAEGYAWLMHDALVNLPKFGSIRGRYPFLLAGDAALIQATALEDWSAIMAKPELVFTYAMQVAVALNTGLYLRRVKKTGFGTTIDDSYEDGPFLQPETFVQAALACCTGQDAPLNGMSDVYVTYPDLLELDALTRVPVTVLEPAGYNIVDGALEVVGVPIACSPYMIFPVAAFDKANPYSGNFVIQPAVKYLRKGALYDKLEAWKLAWAMRIAGYDTSFKVYGDVHGLTKFYADNSDSWTHIPEFVSDGDIMEVYVTAIERRTRHFVELPRLNSPAFFKSVEVSTTIYDTYVQAGTFSVYHASRINLDYVKPVSAGIQVINAGELRNYWGSVRRTQQGLGVVGLTMPAVMPTGERTAGAAHEELIEQADDVSVE</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>