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<entry dataset="TrEMBL" created="2017-03-15" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1L3KLY5</accession>
    <name>A0A1L3KLY5_9VIRU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhv domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <organism evidence="3 4">
        <name type="scientific">Hubei picorna-like virus 21</name>
        <dbReference type="NCBI Taxonomy" id="1923101"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>unclassified Riboviria</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2016" name="Nature" volume="540" first="539" last="543">
            <title>Redefining the invertebrate RNA virosphere.</title>
            <authorList>
                <person name="Shi M."/>
                <person name="Lin X.D."/>
                <person name="Tian J.H."/>
                <person name="Chen L.J."/>
                <person name="Chen X."/>
                <person name="Li C.X."/>
                <person name="Qin X.C."/>
                <person name="Li J."/>
                <person name="Cao J.P."/>
                <person name="Eden J.S."/>
                <person name="Buchmann J."/>
                <person name="Wang W."/>
                <person name="Xu J."/>
                <person name="Holmes E.C."/>
                <person name="Zhang Y.Z."/>
            </authorList>
            <dbReference type="PubMed" id="27880757"/>
            <dbReference type="DOI" id=".1038/nature20167"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">WHBL73090</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX884263">
        <property type="protein sequence ID" value="APG78397.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009337211.1">
        <property type="nucleotide sequence ID" value="NC_033069.1"/>
    </dbReference>
    <dbReference type="GeneID" id="30854717"/>
    <dbReference type="KEGG" id="vg:30854717"/>
    <dbReference type="Proteomes" id="UP000203650">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00205">
        <property type="entry name" value="rhv_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001676">
        <property type="entry name" value="Picornavirus_capsid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033703">
        <property type="entry name" value="Rhv-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029053">
        <property type="entry name" value="Viral_coat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00073">
        <property type="entry name" value="Rhv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhv" evidence="2">
        <location>
            <begin position="316"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="731"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="APG78397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000203650"/>
        </source>
    </evidence>
    <sequence length="801" mass="87869" checksum="F1E25E7D27CB475B" modified="2017-03-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-03-15" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1L3KM22</accession>
    <name>A0A1L3KM22_9VIRU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <organism evidence="10 11">
        <name type="scientific">Hubei picorna-like virus 21</name>
        <dbReference type="NCBI Taxonomy" id="1923101"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>unclassified Riboviria</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2016" name="Nature" volume="540" first="539" last="543">
            <title>Redefining the invertebrate RNA virosphere.</title>
            <authorList>
                <person name="Shi M."/>
                <person name="Lin X.D."/>
                <person name="Tian J.H."/>
                <person name="Chen L.J."/>
                <person name="Chen X."/>
                <person name="Li C.X."/>
                <person name="Qin X.C."/>
                <person name="Li J."/>
                <person name="Cao J.P."/>
                <person name="Eden J.S."/>
                <person name="Buchmann J."/>
                <person name="Wang W."/>
                <person name="Xu J."/>
                <person name="Holmes E.C."/>
                <person name="Zhang Y.Z."/>
            </authorList>
            <dbReference type="PubMed" id="27880757"/>
            <dbReference type="DOI" id=".1038/nature20167"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">WHBL73090</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX884263">
        <property type="protein sequence ID" value="APG78396.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009337210.1">
        <property type="nucleotide sequence ID" value="NC_033069.1"/>
    </dbReference>
    <dbReference type="GeneID" id="30854718"/>
    <dbReference type="KEGG" id="vg:30854718"/>
    <dbReference type="Proteomes" id="UP000203650">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039694">
        <property type="term" value="P:viral RNA genome replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004004">
        <property type="entry name" value="Helic/Pol/Pept_Calicivir-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000605">
        <property type="entry name" value="Helicase_SF3_ssDNA/RNA_vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014759">
        <property type="entry name" value="Helicase_SF3_ssRNA_vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001205">
        <property type="entry name" value="RNA-dir_pol_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007094">
        <property type="entry name" value="RNA-dir_pol_PSvirus"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00680">
        <property type="entry name" value="RdRP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00910">
        <property type="entry name" value="RNA_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00918">
        <property type="entry name" value="CALICVIRUSNS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50507">
        <property type="entry name" value="RDRP_SSRNA_POS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51218">
        <property type="entry name" value="SF3_HELICASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0693">Viral RNA replication</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="SF3 helicase" evidence="9">
        <location>
            <begin position="609"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="domain" description="RdRp catalytic" evidence="8">
        <location>
            <begin position="1576"/>
            <end position="1705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="APG78396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000203650"/>
        </source>
    </evidence>
    <sequence length="1836" mass="208173" checksum="61DE354A426D74AA" modified="2017-03-15" version="1"> </sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
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