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<entry dataset="TrEMBL" created="2017-03-15" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1L3KFP3</accession>
    <name>A0A1L3KFP3_9VIRU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA-directed RNA polymerase</fullName>
            <ecNumber evidence="4">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <organism evidence="6 7">
        <name type="scientific">Changjiang tombus-like virus 8</name>
        <dbReference type="NCBI Taxonomy" id="1922822"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>unclassified Riboviria</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Nature" volume="540" first="539" last="543">
            <title>Redefining the invertebrate RNA virosphere.</title>
            <authorList>
                <person name="Shi M."/>
                <person name="Lin X.D."/>
                <person name="Tian J.H."/>
                <person name="Chen L.J."/>
                <person name="Chen X."/>
                <person name="Li C.X."/>
                <person name="Qin X.C."/>
                <person name="Li J."/>
                <person name="Cao J.P."/>
                <person name="Eden J.S."/>
                <person name="Buchmann J."/>
                <person name="Wang W."/>
                <person name="Xu J."/>
                <person name="Holmes E.C."/>
                <person name="Zhang Y.Z."/>
            </authorList>
            <dbReference type="PubMed" id="27880757"/>
            <dbReference type="DOI" id=".1038/nature20167"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CJLX29920</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="4"/>
    <dbReference type="EMBL" id="KX883090">
        <property type="protein sequence ID" value="APG76241.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009337198.1">
        <property type="nucleotide sequence ID" value="NC_033063.1"/>
    </dbReference>
    <dbReference type="GeneID" id="30854698"/>
    <dbReference type="KEGG" id="vg:30854698"/>
    <dbReference type="Proteomes" id="UP000201089">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039694">
        <property type="term" value="P:viral RNA genome replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007094">
        <property type="entry name" value="RNA-dir_pol_PSvirus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002166">
        <property type="entry name" value="RNA_pol_HCV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00998">
        <property type="entry name" value="RdRP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50507">
        <property type="entry name" value="RDRP_SSRNA_POS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0693">Viral RNA replication</keyword>
    <feature type="domain" description="RdRp catalytic" evidence="5">
        <location>
            <begin position="215"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="APG76241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000201089"/>
        </source>
    </evidence>
    <sequence length="523" mass="59455" checksum="390A24465F8EDE5E" modified="2017-03-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-03-15" modified="2020-04-22" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1L3KFQ0</accession>
    <name>A0A1L3KFQ0_9VIRU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <organism evidence="1 2">
        <name type="scientific">Changjiang tombus-like virus 8</name>
        <dbReference type="NCBI Taxonomy" id="1922822"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>unclassified Riboviria</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2016" name="Nature" volume="540" first="539" last="543">
            <title>Redefining the invertebrate RNA virosphere.</title>
            <authorList>
                <person name="Shi M."/>
                <person name="Lin X.D."/>
                <person name="Tian J.H."/>
                <person name="Chen L.J."/>
                <person name="Chen X."/>
                <person name="Li C.X."/>
                <person name="Qin X.C."/>
                <person name="Li J."/>
                <person name="Cao J.P."/>
                <person name="Eden J.S."/>
                <person name="Buchmann J."/>
                <person name="Wang W."/>
                <person name="Xu J."/>
                <person name="Holmes E.C."/>
                <person name="Zhang Y.Z."/>
            </authorList>
            <dbReference type="PubMed" id="27880757"/>
            <dbReference type="DOI" id=".1038/nature20167"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">CJLX29920</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="KX883090">
        <property type="protein sequence ID" value="APG76240.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009337197.1">
        <property type="nucleotide sequence ID" value="NC_033063.1"/>
    </dbReference>
    <dbReference type="GeneID" id="30854700"/>
    <dbReference type="KEGG" id="vg:30854700"/>
    <dbReference type="Proteomes" id="UP000201089">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="APG76240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000201089"/>
        </source>
    </evidence>
    <sequence length="255" mass="29191" checksum="C0DDC80B9CD13A70" modified="2017-03-15" version="1">MVTTRANSEFLPVTRLSQPDDQPYWTFWDRWKSSFAEFWSTSTITRMCCCVDPEVHLDAQLRRRQHNAVRESLLYTLDYRGDTSIITATMNDLLDEGHVMLQDAAPTPARSPPTINPATLGPTFTTLTVYEPATHHAWSQPQLAPPLNHTRRNLTPVKFVPRFTAAVIVELRSRLGQLPESIPGNALIVEREALRLMRKYSVREVDAVTHLPSIISCYFREDLHYRVETSVSRMSKFQRWLVGEAQPKPSFTPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-03-15" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1L3KG20</accession>
    <name>A0A1L3KG20_9VIRU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Capsid protein</fullName>
        </recommendedName>
    </protein>
    <organism evidence="6 7">
        <name type="scientific">Changjiang tombus-like virus 8</name>
        <dbReference type="NCBI Taxonomy" id="1922822"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>unclassified Riboviria</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2016" name="Nature" volume="540" first="539" last="543">
            <title>Redefining the invertebrate RNA virosphere.</title>
            <authorList>
                <person name="Shi M."/>
                <person name="Lin X.D."/>
                <person name="Tian J.H."/>
                <person name="Chen L.J."/>
                <person name="Chen X."/>
                <person name="Li C.X."/>
                <person name="Qin X.C."/>
                <person name="Li J."/>
                <person name="Cao J.P."/>
                <person name="Eden J.S."/>
                <person name="Buchmann J."/>
                <person name="Wang W."/>
                <person name="Xu J."/>
                <person name="Holmes E.C."/>
                <person name="Zhang Y.Z."/>
            </authorList>
            <dbReference type="PubMed" id="27880757"/>
            <dbReference type="DOI" id=".1038/nature20167"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">CJLX29920</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the icosahedral plant coat protein family.</text>
    </comment>
    <dbReference type="EMBL" id="KX883090">
        <property type="protein sequence ID" value="APG76242.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009337199.1">
        <property type="nucleotide sequence ID" value="NC_033063.1"/>
    </dbReference>
    <dbReference type="GeneID" id="30854699"/>
    <dbReference type="KEGG" id="vg:30854699"/>
    <dbReference type="Proteomes" id="UP000201089">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039617">
        <property type="term" value="C:T=3 icosahedral viral capsid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000937">
        <property type="entry name" value="Capsid_prot_S-dom_vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029053">
        <property type="entry name" value="Viral_coat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00729">
        <property type="entry name" value="Viral_coat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1142">T=3 icosahedral capsid protein</keyword>
    <keyword evidence="3" id="KW-0946">Virion</keyword>
    <feature type="domain" description="Viral_coat" evidence="5">
        <location>
            <begin position="30"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="APG76242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000201089"/>
        </source>
    </evidence>
    <sequence length="346" mass="37496" checksum="C7E72A6A8163CBB1" modified="2017-03-15" version="1">MTNKQQPKKGNLRGAQQKNSVPTMARNDSVRAAPVALATRRNGTAARMTTTNTGVTVTHRSFLMPVTNTLNYTAFSVPCNPGMAGSFPWLCKLARRYEEYRFKKLRYEFRSVTASSQSGVVMMSFDFDAADSAPSTKAEQAQTVPNTETNVWMNNDLVVTPDPKWQYVRSGFLSSNLDIKTYDMGNLWLSTAYGNNVVGGELYVEYTVELRKPTDGPETCGTWTADTGAFSAPVNQTNVVSTGASFPFRRIDNNNFEVVSGGEYIMVCRASGTGLTAVIATPTIASSGTTALVSSIQTCVGGSSTINVLRLRVDTGDVIYFANAGTGTTINATRYWVAPVDYTSIV</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>