<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="http://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
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<entry dataset="TrEMBL" created="2009-06-16" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C3VM11</accession>
    <name>C3VM11_9RHAB</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleoprotein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Nucleocapsid protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">N</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Pike fry sprivivirus</name>
        <dbReference type="NCBI Taxonomy" id="219584"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Negarnaviricota</taxon>
            <taxon>Haploviricotina</taxon>
            <taxon>Monjiviricetes</taxon>
            <taxon>Mononegavirales</taxon>
            <taxon>Rhabdoviridae</taxon>
            <taxon>Alpharhabdovirinae</taxon>
            <taxon>Sprivivirus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2009" name="Arch. Virol." volume="154" first="1489" last="1494">
            <title>Characterization of the complete genome sequence of pike fry rhabdovirus.</title>
            <authorList>
                <person name="Chen H.L."/>
                <person name="Liu H."/>
                <person name="Liu Z.X."/>
                <person name="He J.Q."/>
                <person name="Gao L.Y."/>
                <person name="Shi X.J."/>
                <person name="Jiang Y.L."/>
            </authorList>
            <dbReference type="PubMed" id="19603256"/>
            <dbReference type="DOI" id="10.1007/s00705-009-0455-0"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">F4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Host cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Virion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FJ872827">
        <property type="protein sequence ID" value="ACP27998.1"/>
        <property type="molecule type" value="Viral_cRNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009094121.1">
        <property type="nucleotide sequence ID" value="NC_025356.1"/>
    </dbReference>
    <dbReference type="GeneID" id="20964409"/>
    <dbReference type="KEGG" id="vg:20964409"/>
    <dbReference type="Proteomes" id="UP000159768">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019029">
        <property type="term" value="C:helical viral capsid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030430">
        <property type="term" value="C:host cell cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019013">
        <property type="term" value="C:viral nucleocapsid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3610.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000448">
        <property type="entry name" value="Rhabdo_ncapsid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023331">
        <property type="entry name" value="Rhabdovirus_ncapsid_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023330">
        <property type="entry name" value="Rhabdovirus_ncapsid_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035961">
        <property type="entry name" value="Rhabdovirus_nucleoprotein-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00945">
        <property type="entry name" value="Rhabdo_ncap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140809">
        <property type="entry name" value="SSF140809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="5" id="KW-1139">Helical capsid protein</keyword>
    <keyword evidence="10" id="KW-1035">Host cytoplasm</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9 14" id="KW-0543">Viral nucleoprotein</keyword>
    <keyword evidence="7" id="KW-0946">Virion</keyword>
    <feature type="domain" description="Rhabdo_ncap" evidence="13">
        <location>
            <begin position="9"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ACP27998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000159768"/>
        </source>
    </evidence>
    <sequence length="419" mass="47037" checksum="6E576D65AE80DE23" modified="2009-06-16" version="1">MSVIRIKTNAAVAAVLPANEDQADYPATFFEGGNEIRLYVHRGEKLDVLRQYVYMGLQEKNCKIQHVNAYLYEVLKGEEERLEADWDSFGQKIGNQGEKIGPFKLVKVGDITEGLPDGKLNAEVSAEDDAWLPLFLLGLYRVGRASETAYRTLLMEALIKQCKAIKSDWVSPVTSTHKYFDVWGNDGNYLKIVACVDMFYNHFKKSIKATFRWGTIVSRFKDCAALATLGHLVKITGLTIEEVFTWVLQTEVADELVRMMKPGQEIDNGASYMPYLIDMGISAKSPYSTIKNPSFHFWGQLTSALCRSKRALNARQPDEIDSVSISNAGLLMAYALGSSPDIEQQFSTGDTYRKPPKEGSYLVTEEPKTRAVVDWIAWYSDVDNKPTDEMLLMAKRVAGTISGPRENSVGKWIKQTYGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-06-16" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>C3VM12</accession>
    <name>C3VM12_9RHAB</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoprotein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Protein M1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">P</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Pike fry sprivivirus</name>
        <dbReference type="NCBI Taxonomy" id="219584"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Negarnaviricota</taxon>
            <taxon>Haploviricotina</taxon>
            <taxon>Monjiviricetes</taxon>
            <taxon>Mononegavirales</taxon>
            <taxon>Rhabdoviridae</taxon>
            <taxon>Alpharhabdovirinae</taxon>
            <taxon>Sprivivirus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2009" name="Arch. Virol." volume="154" first="1489" last="1494">
            <title>Characterization of the complete genome sequence of pike fry rhabdovirus.</title>
            <authorList>
                <person name="Chen H.L."/>
                <person name="Liu H."/>
                <person name="Liu Z.X."/>
                <person name="He J.Q."/>
                <person name="Gao L.Y."/>
                <person name="Shi X.J."/>
                <person name="Jiang Y.L."/>
            </authorList>
            <dbReference type="PubMed" id="19603256"/>
            <dbReference type="DOI" id="10.1007/s00705-009-0455-0"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">F4</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template. May act as a chaperone for newly synthesized free N protein, so-called N(0). Plays a role in virion assembly.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the vesiculovirus protein P family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ872827">
        <property type="protein sequence ID" value="ACP27999.1"/>
        <property type="molecule type" value="Viral_cRNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009094122.1">
        <property type="nucleotide sequence ID" value="NC_025356.1"/>
    </dbReference>
    <dbReference type="GeneID" id="20964405"/>
    <dbReference type="KEGG" id="vg:20964405"/>
    <dbReference type="Proteomes" id="UP000159768">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043036">
        <property type="entry name" value="Phosphoprotein_C_viral"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="35"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="191"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ACP27999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000159768"/>
        </source>
    </evidence>
    <sequence length="309" mass="35787" checksum="5B493DD5D4DDF32F" modified="2009-06-16" version="1">MSLNSRLLDSLKAYGNLEKTVKEIETQVSALEEPVPKSVTYVTYENSTSDDEDDQELEDEDDDDLLNDEKVPDYLREERTIVVEEDEEQSEEEREDDLPRVEWGETKIGLDLGFGPGVVVPSISDFDGGTYVKYTGFGQMDPDVRNLISKLMKDLANQVSTKYGYDVDLFDYQGDFLEVFLPNKSHKEEFKADKQEVPLKKADISPKEREKEEESTPVRSEDECGRFPKEKEIKRREKSCLWNAVKSMTIQFAPWKEGDTPLNVTIRELFISEPEFNLHCSETQTELEMALTGIKLRKLYNKLYQKYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-06-16" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>C3VM13</accession>
    <name>C3VM13_9RHAB</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Matrix protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">M</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Pike fry sprivivirus</name>
        <dbReference type="NCBI Taxonomy" id="219584"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Negarnaviricota</taxon>
            <taxon>Haploviricotina</taxon>
            <taxon>Monjiviricetes</taxon>
            <taxon>Mononegavirales</taxon>
            <taxon>Rhabdoviridae</taxon>
            <taxon>Alpharhabdovirinae</taxon>
            <taxon>Sprivivirus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2009" name="Arch. Virol." volume="154" first="1489" last="1494">
            <title>Characterization of the complete genome sequence of pike fry rhabdovirus.</title>
            <authorList>
                <person name="Chen H.L."/>
                <person name="Liu H."/>
                <person name="Liu Z.X."/>
                <person name="He J.Q."/>
                <person name="Gao L.Y."/>
                <person name="Shi X.J."/>
                <person name="Jiang Y.L."/>
            </authorList>
            <dbReference type="PubMed" id="19603256"/>
            <dbReference type="DOI" id="10.1007/s00705-009-0455-0"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">F4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Host endomembrane system</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Virion membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the vesiculoviruses matrix protein family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ872827">
        <property type="protein sequence ID" value="ACP28000.1"/>
        <property type="molecule type" value="Viral_cRNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009094123.1">
        <property type="nucleotide sequence ID" value="NC_025356.1"/>
    </dbReference>
    <dbReference type="GeneID" id="20964406"/>
    <dbReference type="KEGG" id="vg:20964406"/>
    <dbReference type="Proteomes" id="UP000159768">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033645">
        <property type="term" value="C:host cell endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019031">
        <property type="term" value="C:viral envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055036">
        <property type="term" value="C:virion membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039660">
        <property type="term" value="F:structural constituent of virion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009397">
        <property type="entry name" value="Vesiculo_matrix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036711">
        <property type="entry name" value="VSV_matrix_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06326">
        <property type="entry name" value="Vesiculo_matrix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75404">
        <property type="entry name" value="SSF75404"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1043">Host membrane</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0468">Viral matrix protein</keyword>
    <keyword evidence="8" id="KW-0946">Virion</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ACP28000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000159768"/>
        </source>
    </evidence>
    <sequence length="222" mass="25348" checksum="844320706EA06C5D" modified="2009-06-16" version="1">MSTLRKIFGIKKSKGTPPTYEESFATAPVMMDTHDTHSHSIQWMRYQVEMDVHVDVPLKSMSDLLGLLKNWDADYKGSKNKRRFYRLVLFRCALDLHSSGSYSADGSAMYSTRVQGSCYVPHRFGQMPAFRREIETFRYPVHQSGYNGVINLRLSICDLHGEKHGFNLLRECQEISPANFKKYLDLVGLEAACSATGEWILDWTSPGPIDVVPKVPTFFLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-06-16" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>C3VM14</accession>
    <name>C3VM14_9RHAB</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">G</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Pike fry sprivivirus</name>
        <dbReference type="NCBI Taxonomy" id="219584"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Negarnaviricota</taxon>
            <taxon>Haploviricotina</taxon>
            <taxon>Monjiviricetes</taxon>
            <taxon>Mononegavirales</taxon>
            <taxon>Rhabdoviridae</taxon>
            <taxon>Alpharhabdovirinae</taxon>
            <taxon>Sprivivirus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2009" name="Arch. Virol." volume="154" first="1489" last="1494">
            <title>Characterization of the complete genome sequence of pike fry rhabdovirus.</title>
            <authorList>
                <person name="Chen H.L."/>
                <person name="Liu H."/>
                <person name="Liu Z.X."/>
                <person name="He J.Q."/>
                <person name="Gao L.Y."/>
                <person name="Shi X.J."/>
                <person name="Jiang Y.L."/>
            </authorList>
            <dbReference type="PubMed" id="19603256"/>
            <dbReference type="DOI" id="10.1007/s00705-009-0455-0"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">F4</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FJ872827">
        <property type="protein sequence ID" value="ACP28001.1"/>
        <property type="molecule type" value="Viral_cRNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009094124.1">
        <property type="nucleotide sequence ID" value="NC_025356.1"/>
    </dbReference>
    <dbReference type="GeneID" id="20964407"/>
    <dbReference type="KEGG" id="vg:20964407"/>
    <dbReference type="Proteomes" id="UP000159768">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019031">
        <property type="term" value="C:viral envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001903">
        <property type="entry name" value="Rhabd_glycop"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00974">
        <property type="entry name" value="Rhabdo_glycop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="466"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACP28001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000159768"/>
        </source>
    </evidence>
    <sequence length="508" mass="57805" checksum="58CDED080FF4D855" modified="2009-06-16" version="1">MSIYYALFMVSLMSGCESIPIFVPQNQDISWQPVIRPFNYQCPIHGNLPDTFGLKSTKLTFWSPSVFSPGTVSGWICHAAEWKTTCDYRWYGPQYITHSIHSIRPTIEECKRSIKQLESGTDEDLGFPPQSCGWASVTTVSNKNYKVVVHPVHLEPYQGKWVDHEFLGGECNAPVCEMRGNHSIWLTDHILKEECDQHIEETTGTMYGNARRGDNLYVNNFIIDDHHRVYKFQDACRMKFCGMDGIKFLRGDWIEKKGELARLHENVPDCADGTLISGHKPGADLVDTVFNLENLLEFTLCESTKAKINRREEITSVDLSYLAPRVGGLGSIFRVRNGTLERGSTIYMRIEVEGPIVPRLEGFDPRTNQSRVFWDDWDLDGEVYQGFNGIYKGQDQMIHIPLNMIESGLVDEELQRSFQADTIPHPHFSDDGVSDEDIFFDNTGENGNPVDAVVEWVSGWGTSLKFFGMTLIALVFLFIIIRVVIAVIYCLKKPKKTTVESREMRSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-06-16" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>C3VM15</accession>
    <name>C3VM15_9RHAB</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RNA-directed RNA polymerase L</fullName>
            <ecNumber evidence="21">2.1.1.375</ecNumber>
            <ecNumber evidence="6">2.7.7.48</ecNumber>
            <ecNumber evidence="7">2.7.7.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="22">Large structural protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="24">Replicase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="23">Transcriptase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="28" type="primary">L</name>
    </gene>
    <organism evidence="28 29">
        <name type="scientific">Pike fry sprivivirus</name>
        <dbReference type="NCBI Taxonomy" id="219584"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Negarnaviricota</taxon>
            <taxon>Haploviricotina</taxon>
            <taxon>Monjiviricetes</taxon>
            <taxon>Mononegavirales</taxon>
            <taxon>Rhabdoviridae</taxon>
            <taxon>Alpharhabdovirinae</taxon>
            <taxon>Sprivivirus</taxon>
        </lineage>
    </organism>
    <reference evidence="28 29" key="1">
        <citation type="journal article" date="2009" name="Arch. Virol." volume="154" first="1489" last="1494">
            <title>Characterization of the complete genome sequence of pike fry rhabdovirus.</title>
            <authorList>
                <person name="Chen H.L."/>
                <person name="Liu H."/>
                <person name="Liu Z.X."/>
                <person name="He J.Q."/>
                <person name="Gao L.Y."/>
                <person name="Shi X.J."/>
                <person name="Jiang Y.L."/>
            </authorList>
            <dbReference type="PubMed" id="19603256"/>
            <dbReference type="DOI" id="10.1007/s00705-009-0455-0"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="28">F4</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:65440"/>
            <dbReference type="Rhea" id="RHEA-COMP:16798"/>
            <dbReference type="Rhea" id="RHEA-COMP:16801"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156482"/>
            <dbReference type="ChEBI" id="CHEBI:156483"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + H(+) + 2 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:65376"/>
            <dbReference type="Rhea" id="RHEA-COMP:16797"/>
            <dbReference type="Rhea" id="RHEA-COMP:16798"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156483"/>
            <dbReference type="ChEBI" id="CHEBI:156484"/>
            <dbReference type="EC" id="2.1.1.375"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine = a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:65380"/>
            <dbReference type="Rhea" id="RHEA-COMP:16797"/>
            <dbReference type="Rhea" id="RHEA-COMP:16801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156482"/>
            <dbReference type="ChEBI" id="CHEBI:156484"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a 5'-end triphospho-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + GDP + H(+) = a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:65436"/>
            <dbReference type="Rhea" id="RHEA-COMP:16797"/>
            <dbReference type="Rhea" id="RHEA-COMP:16799"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:156484"/>
            <dbReference type="ChEBI" id="CHEBI:156503"/>
            <dbReference type="EC" id="2.7.7.88"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Host cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Virion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the rhabdoviridae protein L family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.375" evidence="21"/>
    <dbReference type="EC" id="2.7.7.48" evidence="6"/>
    <dbReference type="EC" id="2.7.7.88" evidence="7"/>
    <dbReference type="EMBL" id="FJ872827">
        <property type="protein sequence ID" value="ACP28002.1"/>
        <property type="molecule type" value="Viral_cRNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009094125.1">
        <property type="nucleotide sequence ID" value="NC_025356.1"/>
    </dbReference>
    <dbReference type="GeneID" id="20964408"/>
    <dbReference type="KEGG" id="vg:20964408"/>
    <dbReference type="Proteomes" id="UP000159768">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030430">
        <property type="term" value="C:host cell cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004482">
        <property type="term" value="F:mRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039530">
        <property type="entry name" value="L_methyltransferase_rhabdo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039736">
        <property type="entry name" value="L_poly_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026890">
        <property type="entry name" value="Mononeg_mRNAcap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014023">
        <property type="entry name" value="Mononeg_RNA_pol_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025786">
        <property type="entry name" value="Mononega_L_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017234">
        <property type="entry name" value="RNA-dir_pol_rhabdovirus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14314">
        <property type="entry name" value="Methyltrans_Mon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14318">
        <property type="entry name" value="Mononeg_mRNAcap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00946">
        <property type="entry name" value="Mononeg_RNA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037546">
        <property type="entry name" value="RNA_pol_RhabdoV_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04198">
        <property type="entry name" value="paramyx_RNAcap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50526">
        <property type="entry name" value="RDRP_SSRNA_NEG_NONSEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51590">
        <property type="entry name" value="SAM_MT_MNV_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-1035">Host cytoplasm</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="25" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="16" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="28" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="28" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="28" id="KW-0808">Transferase</keyword>
    <keyword evidence="25" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="25" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="13" id="KW-0946">Virion</keyword>
    <feature type="transmembrane region" description="Helical" evidence="25">
        <location>
            <begin position="825"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="25">
        <location>
            <begin position="864"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="domain" description="RdRp catalytic" evidence="26">
        <location>
            <begin position="587"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="domain" description="Mononegavirus-type SAM-dependent 2'-O-MTase" evidence="27">
        <location>
            <begin position="1625"/>
            <end position="1822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00018602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00024452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00024494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00024499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00024634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00026099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00030285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00030436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00031012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS51590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="ACP28002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP000159768"/>
        </source>
    </evidence>
    <sequence length="2095" mass="237584" checksum="06B4A2EBB387BF3B" modified="2009-06-16" version="1"> </sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>