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    <name>A0A0A7HC92_9CAUD</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02347.1"/>
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    <dbReference type="KEGG" id="vg:26636165"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="99" mass="11186" checksum="E0C89D0846F8468C" modified="2015-03-04" version="1">MIMSDGSLVNLQNVARCIMEAGLRKVQELPDSDRKRSYLLAVRTSAMSIKDGQKVPEERIEALLALIYHDQEHKATMRSMRKILQEIGNDKLQSESGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HC99</accession>
    <name>A0A0A7HC99_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA exonuclease A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dexA</name>
        <name evidence="2" type="ORF">VR25_013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02357.1"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5051" evidence="1">
        <location>
            <begin position="4"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="227" mass="25720" checksum="CF0F5BDC210FE26B" modified="2015-03-04" version="1">MIDAIIDFETLGNGSKGAVIDLALITFESDPAVVESFETLVNRGKRIKFSLEYQKGKRLFDTTTMGWWKKQSPEARVNLAPTANDVDTLTGIQQAIDYLKGNGINKYESLMWCRGMSFDFPLFVDLIRDLQRNEGIPERELNTYDLEPVVFWNQRDIRTAIEALSLVRKMCETPLPKGTLDGFVAHDSVHDCAKDILMLKYAQRYALGLDEVPAEEDADPLSLPKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCA9</accession>
    <name>A0A0A7HCA9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_023</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209765.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636185"/>
    <dbReference type="KEGG" id="vg:26636185"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="49" mass="5660" checksum="AD641F25A7757FDA" modified="2015-03-04" version="1">MTQEEAERRAKEALDLLLKIGSKMMEENEKYIKENKVPDGPLVGKRKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCB3</accession>
    <name>A0A0A7HCB3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209770.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="vg:26636190"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="71" mass="8538" checksum="A90688403D6A8CF3" modified="2015-03-04" version="1">MKFNFKKWDDDGRPATKAFGSDAIELGRHLEFPEENYFQLDDFYCRDTDDRNLFWVFIKGGGHFYIDKKYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCB8</accession>
    <name>A0A0A7HCB8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA primase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_033</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209775.1">
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    </dbReference>
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    </dbReference>
    <dbReference type="HAMAP" id="MF_04157">
        <property type="entry name" value="PRIMASE_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046392">
        <property type="entry name" value="PRIMASE_T4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="342" mass="39406" checksum="A94EE550CB02B026" modified="2015-03-04" version="1">MSYIDKEFAVRALSYQPRYREVTGSTFKANCRCKVCGDSQKDSHKARFWAYTNPADGAVYVKCFNCDYSTHISKYIKEFEPDLHREYMVEKYKENAFGRQRTEVAETPKEPEKTPVIEQLAFCERLDTLPEAHPIVKYVKSRCIPAGVWDRLWFTNKWPALVNSVNPGTYKNETNEPRLVIPIFNGKKEIESFQGRALRKDAPQKYITIKAHPEASKVYGVDKIDERKRVWVMEGPIDSLFIPNSIAITGGTLSLEAVPYAETRVWVMDNEPRHPDTIKRMKKLVEAGEAVMFWDNAPWHTKDINEMVKSEGATPEQIESYMADNVAQGLMARMRLSKYAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCC6</accession>
    <name>A0A0A7HCC6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_043</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636205"/>
    <dbReference type="KEGG" id="vg:26636205"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="96" mass="10610" checksum="E1BD19F35E9E2E4F" modified="2015-03-04" version="1">MKTFYHGSCSLANINNMLCPPEETGVLSETGRKKNLNRVFFTEDIGLAKIYAGRAARSIGGEPKLYRVISPVDLVQMNATPGATVYHAEWAFCEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCG3</accession>
    <name>A0A0A7HCG3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anaerobic ribonucleoside-triphosphate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nrdD</name>
        <name evidence="4" type="ORF">VR25_078</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209820.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636240"/>
    <dbReference type="KEGG" id="vg:26636240"/>
    <dbReference type="Proteomes" id="UP000030717">
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    </dbReference>
    <dbReference type="GO" id="GO:0008998">
        <property type="term" value="F:ribonucleoside-triphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01675">
        <property type="entry name" value="RNR_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019777">
        <property type="entry name" value="Form_AcTrfase_GR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012833">
        <property type="entry name" value="NrdD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13597">
        <property type="entry name" value="NRDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02487">
        <property type="entry name" value="NrdD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00850">
        <property type="entry name" value="GLY_RADICAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0556">Organic radical</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycine radical" evidence="3">
        <location>
            <begin position="482"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="2">
        <location>
            <position position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AIZ02422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="605" mass="68017" checksum="55D8C16C1F95DFDC" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCH0</accession>
    <name>A0A0A7HCH0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Modifier of suppressor tRNAs</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cef</name>
        <name evidence="1" type="ORF">VR25_009</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209751.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636171"/>
    <dbReference type="KEGG" id="vg:26636171"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="74" mass="8718" checksum="4D9F0AD5DA9F6CC4" modified="2015-03-04" version="1">MFNEDCVTTSLTAEEFWDTAESDKVIVKKNINEFLCTTDIIYVYENKDAQLPSYALFREESEDGTDFWKEIYNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCI4</accession>
    <name>A0A0A7HCI4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcription modulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">srh</name>
        <name evidence="1" type="ORF">VR25_024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209766.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636186"/>
    <dbReference type="KEGG" id="vg:26636186"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="64" mass="7545" checksum="852FCC3842E9AE2D" modified="2015-03-04" version="1">MRITSWLKDWLVTPGIDDSWVARAEEEMQREAEEWAANGLKDMQEKKTERASLKLMRDIYGDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCI9</accession>
    <name>A0A0A7HCI9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209771.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636191"/>
    <dbReference type="KEGG" id="vg:26636191"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="70" mass="8443" checksum="4E96AD5B93DEACB8" modified="2015-03-04" version="1">MSRLNKRQLKKARKKRAEWLIKNADHELVEELLANQLRHITQLITVKSDHMHMFDWVNEETLKLIAEHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCL2</accession>
    <name>A0A0A7HCL2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209801.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636221"/>
    <dbReference type="KEGG" id="vg:26636221"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="87" mass="10324" checksum="058F55A67CD50EF3" modified="2015-03-04" version="1">MRLYDFNEAGLEHIRECDVVDDDNQPNTIKYWFEAITDRETGQLIKVYVVTDWAVEFSFNVMEDDTPETLIHMAESCIKDAYYDEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCL9</accession>
    <name>A0A0A7HCL9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_069</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209811.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636231"/>
    <dbReference type="KEGG" id="vg:26636231"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020156">
        <property type="entry name" value="DUF5490"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17593">
        <property type="entry name" value="DUF5490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="65" mass="7534" checksum="6C48573F52EB2650" modified="2015-03-04" version="1">MNPESKLSQRVAESRRQFFENMIAQGIDDEVFLKWFWNHKYSSCSGAILISAAMMYEGWKAAKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCN1</accession>
    <name>A0A0A7HCN1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Recombination endonuclease VII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_079</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209821.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636241"/>
    <dbReference type="KEGG" id="vg:26636241"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1800.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004211">
        <property type="entry name" value="Endonuclease_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038563">
        <property type="entry name" value="Endonuclease_7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036309">
        <property type="entry name" value="T4_recomb_endonuclease_dim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015208">
        <property type="entry name" value="T4_recomb_endonuclease_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09124">
        <property type="entry name" value="Endonuc-dimeris"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02945">
        <property type="entry name" value="Endonuclease_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68918">
        <property type="entry name" value="SSF68918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuc-dimeris" evidence="1">
        <location>
            <begin position="104"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="157" mass="18124" checksum="AD045C9FC73C172C" modified="2015-03-04" version="1">MLLTGKLYKEEKQKLYDAQNGKCPICHRDLDSDVQANHLDHDHELNGPKAGKVRGLLCNLCNGTEGQMKHKFSRSGLKGRDVDYLEWLESLLVYLKSDYTENNIHPNFVTDKAKEFGRRGKEEMIQEMLLNGMTYNESDTKTQLMASFKKQLRKSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCN5</accession>
    <name>A0A0A7HCN5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_084</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209826.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636246"/>
    <dbReference type="KEGG" id="vg:26636246"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="106" mass="12569" checksum="C105F7AEEB09DD68" modified="2015-03-04" version="1">MTIENELDVDAVLSEIIEDHDAFTESYEFEFSDYLVPVELGEWTQNGKYQYRQAIYFSKKHNVHVAVNETRTGSYHTDWDHMVPTVELVELQERVVTQTIREWITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCQ0</accession>
    <name>A0A0A7HCQ0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Neck protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209920.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636340"/>
    <dbReference type="KEGG" id="vg:26636340"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021674">
        <property type="entry name" value="Phage_T4_Gp14_neck-protein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11649">
        <property type="entry name" value="T4_neck-protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="261" mass="29752" checksum="8C1CC74725C6A644" modified="2015-03-04" version="1">MTTYDARLFARLEDGTGYDNTNATEILNPYVNFMHHENTQTLADAIVAESIQMRGMSLYYIPRQFVKPDLLFGEDLQSKFDKAWKFAGYLDTFDAYQGDGSIFSKFGMTVNDEITVSINPNLFKHQCNGTEPIAGDLIYFPLDNSLFEITWVQPYDPFYQVGQNAIRKITASKYIYSGEELKPELQRNEGINIPEFSELDLQPIHNIDGLTDISDIPYAESDEINAEAAEYVKPYFVQNGRGLESPPKAKQDSFDDSFFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCQ1</accession>
    <name>A0A0A7HCQ1_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DksA C4-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VR25_104</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209846.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636266"/>
    <dbReference type="KEGG" id="vg:26636266"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="5">
        <location>
            <begin position="8"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="4">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AIZ02448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="85" mass="9672" checksum="31B000506ECC9A15" modified="2015-03-04" version="1">MAVGFAKDGAEQLEMEAVVQAAITHARAQVAVERESAEFCFDCDEKIPEARRQAIKGVIYCVGCQSMHDKVFKREPRNCWHRSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCQ4</accession>
    <name>A0A0A7HCQ4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lysis inhibitor regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rI</name>
        <name evidence="1" type="ORF">VR25_109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209851.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636271"/>
    <dbReference type="KEGG" id="vg:26636271"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="98" mass="11092" checksum="54532EA4D0B142B4" modified="2015-03-04" version="1">MDLIRGLSLSLLLMGCLGPNMSSATDGKFTQYADSAMQIYSQFKEPSVEQSEQFWAFIKTEWNNKSQCVNEITCQIDGRAAAVEYAKLMKVKLEDEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCR7</accession>
    <name>A0A0A7HCR7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative internal head protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ip7</name>
        <name evidence="1" type="ORF">VR25_124</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209866.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636286"/>
    <dbReference type="KEGG" id="vg:26636286"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="99" mass="10806" checksum="2F4FDE043E5532D6" modified="2015-03-04" version="1">MLTYQEFITEAKVPKAFQIGVQGNLDQQYVDAIVASLGKQGVQVDLVDFTKGNTFNIVTSKGSLSKVKKAFGVAQAYEIDHSEFENKGRQNTIKGSGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCR9</accession>
    <name>A0A0A7HCR9_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Highly immunogenic outer capsid protein</fullName>
            <shortName evidence="1">Hoc</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hoc</name>
        <name evidence="2" type="ORF">VR25_198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Capsid decoration protein that binds as a monomer at the center of each major capsid protein hexamer once maturation and expension of the capsid has occured. It only has a marginal effect on head stability. Dispensable for the head morphogenesis and phage infection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Interacts with the major capsid protein; one hoc molecule associates with each hexamer facet.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tevenvirinae Hoc family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209940.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636360"/>
    <dbReference type="KEGG" id="vg:26636360"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098021">
        <property type="term" value="C:viral capsid, decoration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04116">
        <property type="entry name" value="HOC_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038998">
        <property type="entry name" value="HOC"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <feature type="region of interest" description="Interaction with the major capsid protein" evidence="1">
        <location>
            <begin position="345"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="367" mass="38943" checksum="652C7B1AA9D4F85E" modified="2015-03-04" version="1">MAYTVSIAPLTPTAVIGATTNFTATGAGAAVAGTESFVWTVDDVPQDSVIATMDYIAAGPAGSKVIKVVATTTPEEGEPETAEAQTTITVNNKTMAATATLTTSTPTVKVGQEYNASANVTGEPGGATIAYLWSTGEITKDITRAATDAGPVSLTCQITVSAADYDNQVINPEAVVVTVENNTFPEFTVEISGPSTATVDVPFNLTASVSPAIPGATLAYKWDDNSTEATRAITESTEGLKTYTCEVTASQTGFTNSVKSGTKSVTVEEAEPVIPEECPLIYVHPLPVRNTAYIWCGWWVMDAIQKLTSESTDWKKATKEDTPYYCHLAVLAKMLSDYPEVDVQESRNGRIVHRSALEAGIIYDYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCT0</accession>
    <name>A0A0A7HCT0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_134</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209876.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636296"/>
    <dbReference type="KEGG" id="vg:26636296"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="319" mass="37118" checksum="46C50CB95F6C7BFC" modified="2015-03-04" version="1">MMLVIGSRALHNAGLIESKKIENSDWDFIADQGSWNSFKTQMMGQHVHVDNPDVQAFKCMHNGKETYFEAYIVRALTSVRELTDELQEEDFTSSYRLLKYAKANIQKDRLSGFYWATPDICLAIKLSHRYLKNNPFFLKTMSHINYLRNKGVVLNDELQKIMLQRQTETLSYSHPKLDVGKKTFFNDTIYTLDHDSIHEAVALADKPAYKFYMKDDSEVMTSREKFEALPDVIKLAGVYEEACVLALERSQVPNEFNISPSVSFHIALEKVCTSITSGWFREYAWEHYQEVVNMYNTLGREDYVKRFKANQHLIKPFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCT3</accession>
    <name>A0A0A7HCT3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209881.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636301"/>
    <dbReference type="KEGG" id="vg:26636301"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="75" mass="8645" checksum="DFAF0AF997127C6A" modified="2015-03-04" version="1">MTTKTVKEIEDQIRALICEGEQLADKTGEYFHVYADSLQRYIPAGSPEYKKYDWIHGDYGIPEGKGFWFNSSMSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCT8</accession>
    <name>A0A0A7HCT8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209886.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636306"/>
    <dbReference type="KEGG" id="vg:26636306"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="119" mass="13511" checksum="1DD0813204913F2F" modified="2015-03-04" version="1">MRTLYLPGKPEKFVYADKIDKDLMPPFGALSMCIVGVIMMVLCGDMNIISVGVAWALIIAAPFITVLSMILINVWHQNHMNKGYRGRVKEWEQKCVSLQKEHKIKCAEEFIKEVRNGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCV1</accession>
    <name>A0A0A7HCV1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Baseplate hub distal subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_208</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209950.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636370"/>
    <dbReference type="KEGG" id="vg:26636370"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024342">
        <property type="entry name" value="Phage_T4_Gp28"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11110">
        <property type="entry name" value="Phage_hub_GP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="172" mass="19609" checksum="1B2BEB2378BC6C43" modified="2015-03-04" version="1">MNLKLILPTKKIQLGDKEIHVPKLGLKHHNLIKNEANPYAALRKVMQSIFPNLTAAESDFVSLHLLEFNGKLKDKREINGFTYKLDDVYICQRLEFSYQGKTFKFRSNKPYEEFGPVDNLLETLYLGEDVPDFLDMPAFVAKWADDITSTLAIPGPNGPVKGLLKIMELLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCW7</accession>
    <name>A0A0A7HCW7_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Baseplate wedge protein gp6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Baseplate protein that is located next to the tail tube (inner baseplate). Involved in the tail assembly. Involved in sheath contraction.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer; each gp6 molecule in the ring interacts with its two neighbors, forming an N-terminal dimer with one and a C-terminal dimer with the other.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">12 copies of gp6 form a continuous ring that makes up most of the inner baseplate.</text>
    </comment>
    <comment type="induction">
        <text evidence="1">Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the T4likevirus baseplate wedge protein gp6 family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209911.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636331"/>
    <dbReference type="KEGG" id="vg:26636331"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098025">
        <property type="term" value="C:virus tail, baseplate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098003">
        <property type="term" value="P:viral tail assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04102">
        <property type="entry name" value="BP06_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034698">
        <property type="entry name" value="GP6_T4"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1226">Viral baseplate protein</keyword>
    <keyword evidence="1" id="KW-1188">Viral release from host cell</keyword>
    <keyword evidence="1" id="KW-1245">Viral tail assembly</keyword>
    <keyword evidence="1" id="KW-1227">Viral tail protein</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="652" mass="73300" checksum="CF56CF7E9BB0B07C" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCW9</accession>
    <name>A0A0A7HCW9_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(+)--arginine ADP-ribosyltransferase</fullName>
            <ecNumber evidence="2">2.4.2.31</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Alt protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">alt</name>
        <name evidence="4" type="ORF">VR25_213</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">ADP-ribosyltransferase that efficiently ADP-ribosylates one of the two alpha subunits of host RNA polymerase RPOA on an arginine located in the C-terminal region. ADP-ribosylation of RPOA alpha subunit enhances the transcription of viral early genes. Also ribosylates RPOA subunits beta, beta' and sigma 70 and performs an autoribosylation reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-arginyl-[protein] + NAD(+) = H(+) + N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:19149"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:15087"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:142554"/>
            <dbReference type="EC" id="2.4.2.31"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Virion</location>
        </subcellularLocation>
        <text evidence="2">About 25-50 copies per virion. This protein is injected into the bacterial cell along with the viral DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tevenvirinae NAD(+)--arginine ADP-ribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.31" evidence="2"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209955.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636375"/>
    <dbReference type="KEGG" id="vg:26636375"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044423">
        <property type="term" value="C:virion component"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106274">
        <property type="term" value="F:NAD+-protein-arginine ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046782">
        <property type="term" value="P:regulation of viral transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04139">
        <property type="entry name" value="ALT_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003540">
        <property type="entry name" value="ADP-ribosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016225">
        <property type="entry name" value="Phage_T4_Alt-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03496">
        <property type="entry name" value="ADPrib_exo_Tox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000491">
        <property type="entry name" value="Alt_phage"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0946">Virion</keyword>
    <feature type="propeptide" id="PRO_5026393713" evidence="2">
        <location>
            <begin position="1"/>
            <end position="7"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5026393712" description="NAD(+)--arginine ADP-ribosyltransferase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="ADPrib_exo_Tox" evidence="3">
        <location>
            <begin position="413"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="579"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage" evidence="2">
        <location>
            <begin position="7"/>
            <end position="8"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AIZ02557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="683" mass="76361" checksum="94E3388F1652317A" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCX5</accession>
    <name>A0A0A7HCX5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Baseplate wedge subunit and tail pin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_174</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209916.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636336"/>
    <dbReference type="KEGG" id="vg:26636336"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014791">
        <property type="entry name" value="Baseplate_struct_Gp11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043180">
        <property type="entry name" value="Baseplate_struct_Gp11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015982">
        <property type="entry name" value="Baseplate_struct_Gp11_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036214">
        <property type="entry name" value="Gp11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015976">
        <property type="entry name" value="Phage_T4_Gp11_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08677">
        <property type="entry name" value="GP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56558">
        <property type="entry name" value="SSF56558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="221" mass="23906" checksum="CBBA6408CCD1F68E" modified="2015-03-04" version="1">MTTLTNKKASVISRQAGYLQFDYTTTDSTAVAGNRYIGGPSANQTNDGVFYPTVQSAIDDIAFRAELPVGSIITRHENTAPGFISQSDKIKFTGSISGETLGATVLIKVFGFPVEVIVGDSSVLVASKVNDVLLTAISQGLILAETAIDALDQSILNITYNDYQNHIFESKSQYGCVMEQTIVQQPRAGYGQWEYLGAQDVTLQGGSVNGPTSLYYYKRVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCX7</accession>
    <name>A0A0A7HCX7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209965.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636385"/>
    <dbReference type="KEGG" id="vg:26636385"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009258">
        <property type="entry name" value="Phage_T4_Gp30.8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06019">
        <property type="entry name" value="Phage_30_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="122" mass="14327" checksum="CB4AA6B778E055D8" modified="2015-03-04" version="1">MKINLNSYIKGKDHDGYKAIETKEMQWHLYKEQFEFVGCMTPEGPSDDFSWKIMLTNFFTGDTYELKTLILGKIRCKTYEDEETGYSEDVTWYQNGRTTADDLIEKMKAKGELNLDNWIKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCY6</accession>
    <name>A0A0A7HCY6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209975.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636395"/>
    <dbReference type="KEGG" id="vg:26636395"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="92" mass="10313" checksum="81AA8FA9B0524EAB" modified="2015-03-04" version="1">MFPTYSEIVKLVFSQIVSDYLYEIVDVSTELKVHGRLSAILEIMFPDAVDAITVQLHPGAAFAIVPFKIDNHILTISCKMDFQKQTVVVEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD04</accession>
    <name>A0A0A7HD04_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helicase loading protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VR25_258</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210000.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636420"/>
    <dbReference type="KEGG" id="vg:26636420"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04156">
        <property type="entry name" value="HELIC_LOADER_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008944">
        <property type="entry name" value="Phage_T4_Gp59"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015086">
        <property type="entry name" value="Phage_T4_Gp59_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037082">
        <property type="entry name" value="Phage_T4_Gp59_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023197">
        <property type="entry name" value="Phage_T4_Gp59_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015085">
        <property type="entry name" value="Phage_T4_Gp59_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08994">
        <property type="entry name" value="T4_Gp59_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08993">
        <property type="entry name" value="T4_Gp59_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004374">
        <property type="entry name" value="Phage-associated_Gp59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48493">
        <property type="entry name" value="SSF48493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T4_Gp59_N" evidence="1">
        <location>
            <begin position="14"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="T4_Gp59_C" evidence="2">
        <location>
            <begin position="113"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="222" mass="26617" checksum="0A0EE8699B726122" modified="2015-03-04" version="1">MITIRMPPNNNRYINGKSVYQLYLSIKQHFSGRYDIIKYNWTMRISDSAYQKRRDKYFFEKLSDKYTLKELTLIFMSNLVANQDAWIGDISDADALIFYREYIGRLKRIKQVYEDDIKNIYYFSKKVEVKSLQEIFEYNTKVNTSYIFKLLQSNVISFETFCLLDSFLHIINKHDEQTNDLVWDKYSTKLNAYKKILNIDALEARKLFIETVKNCQITLQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD11</accession>
    <name>A0A0A7HD11_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Anti-sigma 70 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">asiA</name>
        <name evidence="1" type="ORF">VR25_268</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210010.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636430"/>
    <dbReference type="KEGG" id="vg:26636430"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015100">
        <property type="entry name" value="AsiA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036486">
        <property type="entry name" value="AsiA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09010">
        <property type="entry name" value="AsiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69070">
        <property type="entry name" value="SSF69070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="91" mass="10704" checksum="D1617F6554B200E9" modified="2015-03-04" version="1">MTKFEIVSEIVTVTSILIKTDREDITMKRDVFIAFLNELGLRNENGNELNNVSFNKLFKSLSEDEIEQIIEQFNEGFEDIHRYLMMYTSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD16</accession>
    <name>A0A0A7HD16_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_273</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210015.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636435"/>
    <dbReference type="KEGG" id="vg:26636435"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="153" mass="17493" checksum="EBE561295F7EFBE8" modified="2015-03-04" version="1">MKTFKERLELLDLALSRETPESLAAKLASYGGEYTEQDVLDEVPEICWELGYWCNDQKFQRRIVSAANRFKLKEGGTLVIPGARHYSKDMAAVLDAVEDKVVSCQVCGDDQGFIDQYSNYWTRKEAMIIATYAGQVRIERGGREDELYSEDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD19</accession>
    <name>A0A0A7HD19_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA topoisomerase II medium subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VR25_278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210020.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636440"/>
    <dbReference type="KEGG" id="vg:26636440"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOP4c" evidence="2">
        <location>
            <begin position="22"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="459" mass="52060" checksum="D0AA48DD244FD07C" modified="2015-03-04" version="1">MSDVLSMMSKQFSDSMGSLNPRSLKDIIDVEALSYAIYTVEGRAIPNMIDGFKPVHRFVMARALDLARGDKNKFHKVASIAGGVADYGYHHGEASAEEATSGLVATYKNEYPMFDGQGNFGSRMVPEASSARYVFARVSKNFYNLFKDTEYAPVHPDEEHKPPAFYLPVIPTVLLNATSGIAVGFATDILPHSFQDVKEAVKAIVEGREPVAPKVKYPEFRGEVVELEEPGKYELHGTYKMTSRTQMEITEIPVQWNLEKYTSKILDPLEEKGFITWKDNCGEHGFGFKIKFRKEYKLDGTEEENHEKIMKDFGLIEKLSQNLTVLNHKGKLAEYTNTLDLIRDFVDVRKTYVQVRIDSKIKETEAAFKLARAKVFFIKEVIDGKVVIQGKPRKKLIEELQASEIYGDYAEKLVAMNIYHMTSDEAKKLADEAKAKKAEHEYWKATDVKTEYLNDLEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD22</accession>
    <name>A0A0A7HD22_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_283</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210025.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636445"/>
    <dbReference type="KEGG" id="vg:26636445"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="114" mass="13353" checksum="80F8036F5BC1973B" modified="2015-03-04" version="1">MSKVFFGNRNIMFFKQISVSEAFDLSYSGGTKVVHLKNLMSAEFAFYQDPETGFYKFIKFRMTMDRDYRDVYYTSYESAINAIREAYGLDSLSLDRLYNASLYTSGFILEQLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD25</accession>
    <name>A0A0A7HD25_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_288</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210030.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636450"/>
    <dbReference type="KEGG" id="vg:26636450"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="88" mass="9829" checksum="288E49FE2CF6E006" modified="2015-03-04" version="1">MDIKLYYAKHKVTGTVVAAMYDASGDGDDVTTELSLSDCKFLRPLVASKEDLEKLIDGKLDNVDGIDILYDLRTALYRGLIEIKEVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD39</accession>
    <name>A0A0A7HD39_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Baseplate hub subunit tail length determinator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209951.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636371"/>
    <dbReference type="KEGG" id="vg:26636371"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="581" mass="64043" checksum="C9FCFE2FABD05FC6" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD57</accession>
    <name>A0A0A7HD57_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_219</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209961.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636380"/>
    <dbReference type="KEGG" id="vg:26636380"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="70" mass="7939" checksum="5A36036CC2828283" modified="2015-03-04" version="1">MFKKLIQKILGTEMVEVTYRVTDVSPWARNIEPYTKTIKMLKSDGGLSIADRLPGYGHWADVDIISVKDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD72</accession>
    <name>A0A0A7HD72_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_239</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209981.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636401"/>
    <dbReference type="KEGG" id="vg:26636401"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="160" mass="18181" checksum="AC47ECBEC98F58AF" modified="2015-03-04" version="1">MSLRDNSFVANPVYISGVKSPVLQKLLKLGSCASTPIEKKATFDFAWAIVDGIDVVRQVTFYAPGAIKPSQIINLDGSNYITIQLWYRMMRPVWEYPEFIEEYNEKERIRELVKSFEYAAKRHGQMQAAAALGDVSESTAYETGKILKTCREELYKELGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD83</accession>
    <name>A0A0A7HD83_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_254</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209996.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636416"/>
    <dbReference type="KEGG" id="vg:26636416"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="84" mass="9694" checksum="D630574A87564095" modified="2015-03-04" version="1">MTKDDFLDAVEKASEQFEVMGVRVHKDRNYGLDVQTYSLWLVGEHSLVTTLVMGVDTYPLLVKFRSLEKATKEMTKLGKWLDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDA0</accession>
    <name>A0A0A7HDA0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210021.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636441"/>
    <dbReference type="KEGG" id="vg:26636441"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="46" mass="5100" checksum="EBC8A342C6645DEF" modified="2015-03-04" version="1">MIKKILGYSLALATLLVALYYGVMFALVQVVLFISDAIMAVHSLIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDA2</accession>
    <name>A0A0A7HDA2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210026.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636446"/>
    <dbReference type="KEGG" id="vg:26636446"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="81" mass="9502" checksum="47F83FABFF913594" modified="2015-03-04" version="1">MKLFKDIVVGEKFVLGNGQQLIRISPLMDNSERPVRTENCLDYPWYRKRFAIENNTECFTVDELMESSEEVDLWDSAVDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDF8</accession>
    <name>A0A0A7HDF8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209764.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636184"/>
    <dbReference type="KEGG" id="vg:26636184"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="162" mass="18872" checksum="225949E3B0E34841" modified="2015-03-04" version="1">MKVYELEFYVRDSAGQTRPYDATACLIMVYNGMNSVTELETRLKDIKLPENIMMKVFHRKNVDVAEGCPFSVSEALHIKGYRHPDPYAEGTADIFYKDTDRNSNERLRGRTYLISTTEDLTEVERQIWKHFDIGLRFTLTEEVLHDTKVRARMYSYGPIGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDG4</accession>
    <name>A0A0A7HDG4_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Small outer capsid protein</fullName>
            <shortName evidence="1">Soc</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">soc</name>
        <name evidence="2" type="ORF">VR25_027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Capsid decoration protein which helps to stabilize the capsid against extremes of pH and temperature. Once maturation and expansion of the capsid has occured, trimers of soc attach the interfaces between the hexamer of the major capsid protein. Acts as a 'glue' between neighboring hexameric capsomers. Dispensable for the head morphogenesis and phage infection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotrimer. Interacts with the major capsid protein; three soc molecules associate with each interface between the major capsid protein facets.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tevenvirinae Soc family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209769.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636189"/>
    <dbReference type="KEGG" id="vg:26636189"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098021">
        <property type="term" value="C:viral capsid, decoration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04115">
        <property type="entry name" value="SOC_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031743">
        <property type="entry name" value="Soc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038151">
        <property type="entry name" value="Soc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16855">
        <property type="entry name" value="Soc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1232">Capsid decoration protein</keyword>
    <keyword evidence="1" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="77" mass="8338" checksum="FBB22264263D76C6" modified="2015-03-04" version="1">MGGFVNIKTFTHAAGEGKEVKGTEVSVPFEIYSNAHRIANAHYQTFPSAVAAYSTVVTDAADWKTKNEAMFTPTDIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDI0</accession>
    <name>A0A0A7HDI0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Discriminator of mRNA degradation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dmd</name>
        <name evidence="1" type="ORF">VR25_042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209784.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636204"/>
    <dbReference type="KEGG" id="vg:26636204"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035137">
        <property type="entry name" value="Dmd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17587">
        <property type="entry name" value="Dmd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="68" mass="7807" checksum="CA8278D9403F3533" modified="2015-03-04" version="1">MGNLAKVMFIGWFENGNMFTKEVTLDVSDKDQIQWVTSQFAEVNNALVKAFVGDNLVFESDWRSEETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDK3</accession>
    <name>A0A0A7HDK3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209804.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636224"/>
    <dbReference type="KEGG" id="vg:26636224"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="67" mass="8002" checksum="47A0AD6EF6466316" modified="2015-03-04" version="1">MALVNKPFKRLLVGAAFRLRSYGNICIKQTETEYKMIGQYSDGIFQIEPVAKVWVDSHQLKKWWKRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDK8</accession>
    <name>A0A0A7HDK8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209809.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636229"/>
    <dbReference type="KEGG" id="vg:26636229"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020303">
        <property type="entry name" value="DUF5495"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17599">
        <property type="entry name" value="DUF5495"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="88" mass="10435" checksum="F8BF235EDF125B68" modified="2015-03-04" version="1">MIKIKLSHYEKNLEMITMKEELLNDIRFTGYAVQFNDVGVLQIEGDHFIIEYEFKQYWLYAKDEVGGIDYVDQFDKLDDVLEAAQLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDL4</accession>
    <name>A0A0A7HDL4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_072</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209814.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636234"/>
    <dbReference type="KEGG" id="vg:26636234"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="84" mass="9788" checksum="18E26CF40BF1DEC6" modified="2015-03-04" version="1">MSLKLHAMKNVITLNLDDERLIFLTVTDKNIEIANGPKTYCCPVKNWKHVTFLTLSERLKDLKLDLGIKDIQYIKNLIGYKLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDR1</accession>
    <name>A0A0A7HDR1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_117</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209859.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636279"/>
    <dbReference type="KEGG" id="vg:26636279"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="180" mass="20632" checksum="B4D13199E86DAA16" modified="2015-03-04" version="1">MKKVIATLLLTVSMSAHSVEPTFSNEQMENLQYAYAFGEQFQKNGKYKENPHQHNGLGYIMAGLTWQESSAGVNTGLNKDKHHAYGIFQNYLPTVRERVKQVGWTMTDKEIIKMISKRENSARWAYIEFSYWLNIHKGDIRKTLSSYNAGWNVKAGNTYASQVLEKANYLKSRGLLKTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDU0</accession>
    <name>A0A0A7HDU0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209894.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636314"/>
    <dbReference type="KEGG" id="vg:26636314"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="127" mass="14462" checksum="49D7A0C1FC3C94A4" modified="2015-03-04" version="1">MYKVYADYQANPSDKPECQIGWAHDTLLEAVDKAQQLGYSYVDIVQQPSGTVITLEEFKNIKTNFLLFAGDSYYPRGGYADLIAKAATEDELRDIIKENENKPCYGSNRFDWWQIVNANTHTIVDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDV2</accession>
    <name>A0A0A7HDV2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative mobile endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VR25_162</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209904.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636324"/>
    <dbReference type="KEGG" id="vg:26636324"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="219" mass="25860" checksum="F7046B3E91E23311" modified="2015-03-04" version="1">MNYQFIYSSLIERARNRVLISYKESHHIIPKCMGGSNAPDNLVDLTPEEHYVAHQLLVKIYPTNPGLSFAATSMSQSSKYLKRNNKLFGWLRRRHADNISKSQTGKVYFTNGVKSIKLFPWEDVPDGFVKGRHYSPTKGTKHSRNNGHFKNKEIQDELRKRRWEKDRQEMCKNFGVDTVEQARELVLAYKKELHPRYWVKPMLERYPFMTKLRLNTLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDW2</accession>
    <name>A0A0A7HDW2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Baseplate tail fiber connector</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209914.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636334"/>
    <dbReference type="KEGG" id="vg:26636334"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019076">
        <property type="term" value="P:viral release from host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008987">
        <property type="entry name" value="Baseplate_struct_prot_Gp9/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036240">
        <property type="entry name" value="Gp9-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027411">
        <property type="entry name" value="Gp9/Gp10_mid_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027412">
        <property type="entry name" value="Gp9_C_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07880">
        <property type="entry name" value="T4_gp9_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50017">
        <property type="entry name" value="SSF50017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="289" mass="31864" checksum="478C78FFB735BD27" modified="2015-03-04" version="1">MINQTPKLLIDVGEIGNASTGDILYDGGRKINEDFDNVYNTFGDQRLYSIDNGQNSQVLHATGYYQKATNIIEWNTPVALGSLRDVDTSKGVVTARIARGKMGEGIIFINSNGTLSPTQSLEIELQGTDTFVSAPTNKIRFTSPYTKITLWCIDDANGVGTWDYSIENMFGVKHIPLDRTYNIGLNARDIPIALRGDFKTMKLLLTAISTDETKYKASEVMLFVDTQANQVYSTEYGVLRRGHVNDDDELYTINFKIGADNFVTATVSAPVSMKLAFKVAETQTIGVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDX6</accession>
    <name>A0A0A7HDX6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Tail sheath protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">VR25_182</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the myoviridae tail sheath protein family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209924.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636344"/>
    <dbReference type="KEGG" id="vg:26636344"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098027">
        <property type="term" value="C:virus tail, sheath"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099000">
        <property type="term" value="P:viral genome ejection through host cell envelope, contractile tail mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035326">
        <property type="entry name" value="Phage_sheath_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035089">
        <property type="entry name" value="Phage_sheath_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020287">
        <property type="entry name" value="Tail_sheath_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04984">
        <property type="entry name" value="Phage_sheath_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17482">
        <property type="entry name" value="Phage_sheath_1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17481">
        <property type="entry name" value="Phage_sheath_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1242">Viral contractile tail ejection system</keyword>
    <keyword evidence="8" id="KW-1171">Viral genome ejection through host cell envelope</keyword>
    <keyword evidence="3" id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword evidence="4" id="KW-1227">Viral tail protein</keyword>
    <keyword evidence="7" id="KW-1229">Viral tail sheath protein</keyword>
    <keyword evidence="6" id="KW-0946">Virion</keyword>
    <keyword evidence="9" id="KW-1160">Virus entry into host cell</keyword>
    <feature type="domain" description="Phage_sheath_1N" evidence="11">
        <location>
            <begin position="176"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Phage_sheath_1" evidence="10">
        <location>
            <begin position="349"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Phage_sheath_1C" evidence="12">
        <location>
            <begin position="547"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AIZ02526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="659" mass="71472" checksum="789661D7B2D40643" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE02</accession>
    <name>A0A0A7HE02_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_202</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209944.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636364"/>
    <dbReference type="KEGG" id="vg:26636364"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024362">
        <property type="entry name" value="DUF2685"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10886">
        <property type="entry name" value="DUF2685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="55" mass="6020" checksum="45F7DB14C94DF57A" modified="2015-03-04" version="1">MSDKICVVCKTPIDSALVVDTDQGPVHPGACYNYVQSLPVTENTQEQLNETQLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE55</accession>
    <name>A0A0A7HE55_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_232</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209974.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636394"/>
    <dbReference type="KEGG" id="vg:26636394"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="180" mass="20004" checksum="9CBFFF9AFEFDCCAB" modified="2015-03-04" version="1">MSDFFEEGKFYKFTSENAKKQFIAGGWAANYQIAGYIGMTPFEVKIVPDAISGGKKVCEIRLIDENDFVDLPKISGTQNRHHGALFVSAGPLSDEFDYFIQAEVGVKPEVEPVPVKLASVWKLLVVKNGKIEINSRHVSKEYAEGEAERLLSRGTAEDCYIIKGDITKASIVKQVKQETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE70</accession>
    <name>A0A0A7HE70_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="4">SSB protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Helix-destabilizing protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">VR25_257</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Single-stranded DNA-binding protein that participates in viral DNA replication, recombination, and repair. Coats the lagging-strand ssDNA as the replication fork advances. Stimulates the activities of viral DNA polymerase and the replicative helicase, probably via its interaction with the helicase assembly factor. Together with the replicative helicase and the helicase assembly factor, promotes pairing of two homologous DNA molecules containing complementary single-stranded regions and mediates homologous DNA strand exchange. Promotes also the formation of joint molecules. mRNA specific autogenous translational repressor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer in the absence of DNA, monomer when binding DNA. Interacts with the DNA helicase assembly protein; a ternary complex between the helicase assembly protein, the single-stranded DNA-binding protein and ssDNA is an obligatory intermediate in the helicase loading mechanism. Part of the replicase complex that includes the DNA polymerase, the polymerase clamp, the clamp loader complex, the single-stranded DNA binding protein, the primase, the replicative helicase and the helicase assembly factor. Interacts (via C-terminus) with the viral SF1 dDA helicase. Interacts with the viral SF2 UvsW repair helicase.</text>
    </comment>
    <comment type="domain">
        <text evidence="4">The acidic C-terminus is involved in modulating the ssDNA binding properties. The N-terminus LAST motif is involved in the cooperative binding of the protein to single-stranded nucleic acids.</text>
    </comment>
    <comment type="domain">
        <text evidence="4">The acidic C-terminus is involved in modulating the ssDNA binding properties. The N-terminus LAST motif is involved in the cooperative binding of the protein to ssDNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Tequatrovirus single-stranded DNA-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209999.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636419"/>
    <dbReference type="KEGG" id="vg:26636419"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039693">
        <property type="term" value="P:viral DNA genome replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.198.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04152">
        <property type="entry name" value="SSB_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012339">
        <property type="entry name" value="Phage_T4_Gp32_ssDNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044947">
        <property type="entry name" value="Phage_T4_Gp32_ssDNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046395">
        <property type="entry name" value="SSB_T4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08804">
        <property type="entry name" value="gp32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0678">Repressor</keyword>
    <keyword evidence="3 4" id="KW-1194">Viral DNA replication</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="gp32" evidence="6">
        <location>
            <begin position="41"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="LAST" evidence="4">
        <location>
            <begin position="5"/>
            <end position="9"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="265"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00018590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AIZ02601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="303" mass="33601" checksum="A1E1A19F68CF4D25" modified="2015-03-04" version="1">MSMFKRKNPADLAASLNALKGGSGFSSDDKKEWKLKDTDGVGSAVIRFLPSKNEENPSPFIKLVNHGFKNAGQWYIENCTSTHGDYENCPVCAYMNKNDLYNTNESEYRKLKRNTSYWANILVIKDPAVPSNEGQVFKYRFGKKIMDKINQMVEVDVDMGETAIDVTCPFEGANFVLKSKMVSGYKNYDDSKFMNQSEIAGINDEAFQKKLWDEMSDLNELLVFKSLEENQKKFSKVMGTAALGGAASKAAAQADKLGADLDDFDKDMEDFTSSKPAKSERTATAPSTPEPSDDGLDDLLAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE74</accession>
    <name>A0A0A7HE74_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210004.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636424"/>
    <dbReference type="KEGG" id="vg:26636424"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="1299" mass="141901" checksum="56B1DED40C7A9AFD" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE77</accession>
    <name>A0A0A7HE77_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Holin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">t</name>
        <name evidence="3" type="ORF">VR25_267</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of micron-scale pores (holes) causing host cell membrane disruption and endolysin escape into the periplasmic space. Determines the precise timing of host cell lysis. Participates with the endolysin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles from the host cell.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homomultimer. Interacts (via C-terminus) with antiholin (via C-terminus); this interaction blocks the holin homomultimerization and delays host cell lysis. Interacts (via N-terminus) with the lysis inhibition accessory protein rIII; this interaction stabilizes the holin-antiholin complex thereby resulting in a robust block of the hole formation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cell inner membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
        <text evidence="1">Classified as a class III holin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the T4likevirus holin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210009.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636429"/>
    <dbReference type="KEGG" id="vg:26636429"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020002">
        <property type="term" value="C:host cell plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034291">
        <property type="term" value="F:canonical holin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04104">
        <property type="entry name" value="HOLIN_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020982">
        <property type="entry name" value="Phage_T4_GpT_holin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11031">
        <property type="entry name" value="Phage_holin_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0204">Cytolysis</keyword>
    <keyword evidence="1" id="KW-1030">Host cell inner membrane</keyword>
    <keyword evidence="1" id="KW-0578">Host cell lysis by virus</keyword>
    <keyword evidence="1" id="KW-1032">Host cell membrane</keyword>
    <keyword evidence="1" id="KW-1043">Host membrane</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1 2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-1188">Viral release from host cell</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="topological domain" description="Periplasmic" evidence="1">
        <location>
            <begin position="49"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="217" mass="24450" checksum="0842BE0EAEC43A68" modified="2015-03-04" version="1">MEPKVGISIPDLLFGLLDRIFKDNATGKVVFSRVLVIVLLFLMAVIWYKGDAILDAYRDASYASYTEMIRQDQDNRFKIAAIEQIQIVHSSSGADFTAIYSFRPTNLNYFVDMVGYEGILPESVDEKNLGGFPIDKTSAEYLAGVNGNYFESGTESVFLPTKKKSSFEYMFSCPFFNLENVYAGTVSLYWYKQKPDLGFDRLSAMCGQAGRTLGRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE80</accession>
    <name>A0A0A7HE80_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_272</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210014.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636434"/>
    <dbReference type="KEGG" id="vg:26636434"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="91" mass="10660" checksum="7A9FBF35466D3E07" modified="2015-03-04" version="1">MNLKQLQIDAIEGHINHIKRLNAMMEDNWGTYVNQPAWDALDHEYINHISPDDIHKNMSGLKPFLRDMYIATNKGIISSLEYQLRKLHEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE82</accession>
    <name>A0A0A7HE82_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_277</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210019.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636439"/>
    <dbReference type="KEGG" id="vg:26636439"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="71" mass="8319" checksum="4A8E360A81981086" modified="2015-03-04" version="1">MFTAQQNEGQEYINAKFKSNKEACYYYFDMFKLANSKEERKQAIDVIVSTSHMKRTVVQSYASNYMKSIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFS2</accession>
    <name>A0A0A7HFS2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_031</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209773.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636193"/>
    <dbReference type="KEGG" id="vg:26636193"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="65" mass="6910" checksum="396F056C0C9A96EB" modified="2015-03-04" version="1">MLKLSSLIQAIKGSRKRTILALSILCSVLLWNFIVAPIALAHGLVLPVVAFESVVDVSLALIGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFS6</accession>
    <name>A0A0A7HFS6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_036</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209778.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636198"/>
    <dbReference type="KEGG" id="vg:26636198"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="73" mass="8711" checksum="0F977CE16A48D2D9" modified="2015-03-04" version="1">MFVLTQFSKATYSYSCQWEVFIDTPSPKYGVFGRVTTQAYVARPTKRQIRKLKKAHRQLIKRREQYECNVYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFU1</accession>
    <name>A0A0A7HFU1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209793.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636213"/>
    <dbReference type="KEGG" id="vg:26636213"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="68" mass="7965" checksum="9F63B3FD1E9A2DE2" modified="2015-03-04" version="1">MNSIAQLTVSDMGNIIIPAPAWINLPIDEQIQYQVKETLEKHPERKVIMCFTYDENRHPQMQKQVVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFU7</accession>
    <name>A0A0A7HFU7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RNA polymerase binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpbA</name>
        <name evidence="1" type="ORF">VR25_056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209798.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636218"/>
    <dbReference type="KEGG" id="vg:26636218"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019725">
        <property type="entry name" value="Phage_T4_P15K_Rpol-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10789">
        <property type="entry name" value="Phage_RpbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="141" mass="16048" checksum="3DF99DF4C350AE46" modified="2015-03-04" version="1">MNRENIMNNVTAKDIQVKTIRTDANPHNQNRIRKSWVLACDEVSATRLKSLPQEVKFMLYGVIDTDVSDKWIELMQRHYTESLAAGAKLVIDRDGSERLEDDYCVDFDDHLVQAGSIIAAQLPEYIESLPEAIRKQMAVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFW1</accession>
    <name>A0A0A7HFW1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_071</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209813.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636233"/>
    <dbReference type="KEGG" id="vg:26636233"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035133">
        <property type="entry name" value="DUF5499"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17603">
        <property type="entry name" value="DUF5499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="97" mass="11757" checksum="AB162E7C90E64D88" modified="2015-03-04" version="1">MGKTIRRKELSVKDFCYSGRRQAPDGVSQEQVEENIFRSDKWKRMRGVDSEVKNEMNRQLRKEVRQLKKDVYVEDDFDYNTSHRVAKRKSNECYRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFX0</accession>
    <name>A0A0A7HFX0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_081</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209823.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636243"/>
    <dbReference type="KEGG" id="vg:26636243"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="90" mass="10411" checksum="7B42C5C0B6BF9F03" modified="2015-03-04" version="1">MFLEIVNIHAAAQSGFMKELQDAGFKNGDVIQALRQRFDPDVKCNVWDVVETDEYLFDTIEIEGSWTCITEYMIIDNGNVECHYPCFRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFY0</accession>
    <name>A0A0A7HFY0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209833.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636253"/>
    <dbReference type="KEGG" id="vg:26636253"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="269"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="301" mass="34555" checksum="A530117BAA887C4D" modified="2015-03-04" version="1">MKNYLDYDMKIKTRAEYASSYEPHDGRVTRLIAMNSLVNFGKIKSGSATQGYGQRIVRINSLNDYCRRPAFLFGATVRKSIKEILAGGFRIRKAPVNIKNYNFNSNNLIINIKNDGVQIKFKPTTKGDVALCHNFKEVMGIALFYMRHAVESYTFDEDTNYIHQTEKFLKTIAIDIKLTKEYLLSYAPYQEKKEPEMERTPTAAYGPAFAGQFKSYDQTKISPLDVKNMYKWNVQPSSSLEIFNPTMKPIESYHADAIKESVNRLNGLIEDEKKGIQDVLNRIKNMETQRNKLQAAIKALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFZ6</accession>
    <name>A0A0A7HFZ6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209848.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636268"/>
    <dbReference type="KEGG" id="vg:26636268"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="78" mass="9393" checksum="FF60245586A16EAA" modified="2015-03-04" version="1">MKLTNTMVSLEYETNNHILEIKIFDDRSIFADYRGYRIRLEKEQLKEVELFKETLKSCGCKLKNTQVQELISTINKYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG02</accession>
    <name>A0A0A7HG02_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Thymidine kinase</fullName>
            <ecNumber evidence="3 11">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">tk</name>
        <name evidence="13" type="ORF">VR25_111</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + thymidine = ADP + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the thymidine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="3 11"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209853.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636273"/>
    <dbReference type="KEGG" id="vg:26636273"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00124">
        <property type="entry name" value="Thymidine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020633">
        <property type="entry name" value="Thymidine_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="PTHR11441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00603">
        <property type="entry name" value="TK_CELLULAR_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="8 11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AIZ02455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="190" mass="21153" checksum="755C3827FA9D9D6B" modified="2015-03-04" version="1">MASLIYHYAAMNAGKTASLLTAAYSYKERGMSVLLLKPVIDNRDSESEIKSRIGISQEANLVTADMNLFEFYKWAESQKDIHCVLVDEAQFLLPEQIDQLARVVDNYNIPVMCYGLRTDFRGQLFPGSARLLAISDKLVELKGVCHCGRKATMTARVIDGAAVKDGEQVLVGGNESYVSLCRKHWLELTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG25</accession>
    <name>A0A0A7HG25_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209873.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636293"/>
    <dbReference type="KEGG" id="vg:26636293"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="78" mass="9149" checksum="720317CA182AB17F" modified="2015-03-04" version="1">MSIAIYIKSESCDSYLYSYDTGTSEEKIKEDLESDLDMFRPISDYRVQTSDSESPSTETRIEIIMAEIFKKSWERDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG34</accession>
    <name>A0A0A7HG34_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_141</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209883.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636303"/>
    <dbReference type="KEGG" id="vg:26636303"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="93" mass="10519" checksum="85F0548EEAA11F47" modified="2015-03-04" version="1">MMNDNHNQPELLAAVKEIHEAIRRAEEIADKYETHFNIYPARGMGGDYYSPGALKADLEHWENYGEAQYAIVNQHDYTTDLAEGGWVSSSAEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG39</accession>
    <name>A0A0A7HG39_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209888.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636308"/>
    <dbReference type="KEGG" id="vg:26636308"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="50"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="197" mass="22318" checksum="28B2EAEB6FFE5DE5" modified="2015-03-04" version="1">MNTLKKLVEFIRSKLGTAMAQNLSIEDQYTKAASTLIDKITELQTAHVKSVNEEKRIRELANEKDQLAASKEREIRKLIADGADVQVHAKLGLLYRRTAKQLRKKADDYVEMRNEIKLKVKELDDSRQELAVKLEYIRETRKVSALGIATADDVVEIAALTKIDIEDTLMRVETFKGPQVGVDTTSADIEEYINSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG62</accession>
    <name>A0A0A7HG62_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Baseplate central spike protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Peptidoglycan hydrolase</fullName>
            <ecNumber evidence="6">3.2.1.17</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">VR25_166</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <molecule>Baseplate central spike protein</molecule>
        <text evidence="6">Baseplate central spike complex-associated lysozyme that is essential for the localized hydrolysis of bacterial cell wall, so that the tail tube, through which the phage DNA is ejected, can penetrate to the host inner membrane. The tail lysozyme complex at the tip of the tail tube penetrates through the outer membrane into the periplasm. This way, lysozyme domain is released and locally digests the peptidoglycan layer to make a hole to let the tube penetrate to the inner membrane. Involved in the tail assembly.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>Hydrolysis of (1-&gt;4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the glycosyl hydrolase 24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.17" evidence="6"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209908.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636328"/>
    <dbReference type="KEGG" id="vg:26636328"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04151">
        <property type="entry name" value="NEEDLE_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002196">
        <property type="entry name" value="Glyco_hydro_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010609">
        <property type="entry name" value="Gp5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009590">
        <property type="entry name" value="Gp5_OB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023347">
        <property type="entry name" value="Lysozyme_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046397">
        <property type="entry name" value="NEEDLE_T4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001165">
        <property type="entry name" value="T4-type_lysozyme"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06715">
        <property type="entry name" value="Gp5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06714">
        <property type="entry name" value="Gp5_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00959">
        <property type="entry name" value="Phage_lysozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00684">
        <property type="entry name" value="T4LYSOZYME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="4 6 7" id="KW-0081">Bacteriolytic enzyme</keyword>
    <keyword evidence="6" id="KW-1235">Degradation of host cell envelope components during virus entry</keyword>
    <keyword evidence="6" id="KW-1236">Degradation of host peptidoglycans during virus entry</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0426">Late protein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1226">Viral baseplate protein</keyword>
    <keyword evidence="6" id="KW-1171">Viral genome ejection through host cell envelope</keyword>
    <keyword evidence="6" id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-1188">Viral release from host cell</keyword>
    <keyword evidence="6" id="KW-1245">Viral tail assembly</keyword>
    <keyword evidence="6" id="KW-1227">Viral tail protein</keyword>
    <keyword evidence="6" id="KW-0946">Virion</keyword>
    <keyword evidence="6" id="KW-1160">Virus entry into host cell</keyword>
    <feature type="chain" id="PRO_5035348868" description="Baseplate central spike protein" evidence="6">
        <location>
            <begin position="1"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Gp5_OB" evidence="8">
        <location>
            <begin position="33"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AIZ02510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="576" mass="63456" checksum="690020BB09C11E06" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG68</accession>
    <name>A0A0A7HG68_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Baseplate wedge subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209913.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636333"/>
    <dbReference type="KEGG" id="vg:26636333"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036327">
        <property type="entry name" value="Gp8_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015298">
        <property type="entry name" value="Phage_T4_Gp8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09215">
        <property type="entry name" value="Phage-Gp8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89433">
        <property type="entry name" value="SSF89433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage-Gp8" evidence="1">
        <location>
            <begin position="10"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="334" mass="38169" checksum="85DF4FAD63FBABBB" modified="2015-03-04" version="1">MNNSTIVYRSIVTSKFRTEKMYNFYGAIGDSATENTMYVTFGRAEPWAANENDPGFAPPYPVDDAQGVEDVWTNMMGAVKVYKSMLDCVVPRKDWGDVRYPNPLNFQIGEIVVSNTAPYNRTDVGKGWMVYRCVDVPESGTCSIYSITNKQECLKLGGKWTSDYASSRAPSGTGDTEGRVDMGDGYLWEYLYEIPPDVSINRCTNEYIVVPWPEEIAEDPERWGYKDNLTWQQDDYGLIYRIKGNTIRFKAFMDSIYFPQFSLPGNKGFRQISIVANPLEIKAAPNDPNIKATKEYYDAIDLSRHSGEMIYMENRPPVYRAMDQTEEVNIIFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG73</accession>
    <name>A0A0A7HG73_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fibritin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">wac</name>
        <name evidence="2" type="ORF">VR25_176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209918.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636338"/>
    <dbReference type="KEGG" id="vg:26636338"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012473">
        <property type="entry name" value="Fibritin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07921">
        <property type="entry name" value="Fibritin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01880">
        <property type="entry name" value="FIBRITIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibritin_C" evidence="1">
        <location>
            <begin position="374"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="528" mass="56570" checksum="A393F19778252158" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG99</accession>
    <name>A0A0A7HG99_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636358"/>
    <dbReference type="KEGG" id="vg:26636358"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="526" mass="52553" checksum="9A9E836CFA0AD42E" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGA4</accession>
    <name>A0A0A7HGA4_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UvsW-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209943.1">
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    </dbReference>
    <dbReference type="GeneID" id="26636363"/>
    <dbReference type="KEGG" id="vg:26636363"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.210">
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    </dbReference>
    <dbReference type="InterPro" id="IPR020975">
        <property type="entry name" value="UvsW.1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038341">
        <property type="entry name" value="UvsW_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11637">
        <property type="entry name" value="UvsW-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvsW-1" evidence="1">
        <location>
            <begin position="20"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="75" mass="8643" checksum="230677530CD513C9" modified="2015-03-04" version="1">MKSFEEIMYEAAIESFMSKIGSCQTMDGLKELEGYYKKRSKEAELKDSDDISVRDALAGKRAELEDMDDEEDEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGB9</accession>
    <name>A0A0A7HGB9_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="3">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">VR25_005</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="3"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209747.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636167"/>
    <dbReference type="KEGG" id="vg:26636167"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031660">
        <property type="entry name" value="TOPRIM_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16898">
        <property type="entry name" value="TOPRIM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HATPase_c" evidence="5">
        <location>
            <begin position="47"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AIZ02349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="609" mass="68317" checksum="9F2F6F22E3A0F016" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGC3</accession>
    <name>A0A0A7HGC3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Modifier of transcription</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">motB</name>
        <name evidence="1" type="ORF">VR25_010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209752.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636172"/>
    <dbReference type="KEGG" id="vg:26636172"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020230">
        <property type="entry name" value="Tscrpt_reg_MotB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17613">
        <property type="entry name" value="motB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="167" mass="18817" checksum="726D3623EA78AD96" modified="2015-03-04" version="1">MITISDIGGIVRVSKQSRSKAAGRLVEVVSIQLKEGVRLENAEVKVRVIPKNGQTETQFGYVRAKFLESTEFTGYIAPVVEEVETIDQSHVGVDFKWKLGKGVFFVSPKPFEYICKYGPTYETTSMSGYITDQWVEEGVKLYNIVFLGTFKVIPESFIVEYADIHFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGD0</accession>
    <name>A0A0A7HGD0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR20_020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209762.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636182"/>
    <dbReference type="KEGG" id="vg:26636182"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="77" mass="8668" checksum="B8B15D18773B59F7" modified="2015-03-04" version="1">MNWLTNIPTSAQDIDRKHAHKEIEQQKINRVQRLKIESETIKAKRPTESKSSYSSCQSPIGMAADIAIFGVPLGVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGE4</accession>
    <name>A0A0A7HGE4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209777.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636197"/>
    <dbReference type="KEGG" id="vg:26636197"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="63" mass="7085" checksum="CD2681302B433AC5" modified="2015-03-04" version="1">MSAMCTGSKISVFEIFEEYEIVSQDQEAIHVIADDGVTWIIPLYHEDTYEVTDANGDKAIFVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGE8</accession>
    <name>A0A0A7HGE8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Head assembly cochaperone with GroEL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209968.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636388"/>
    <dbReference type="KEGG" id="vg:26636388"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="107" mass="11517" checksum="204CFC7E98FC7602" modified="2015-03-04" version="1">MELPIKAVGEYIILVSEPKQAGDEETTASGIVIGKLHQGEIPEMCEVFSIGSDVPEGFCEVGDLTPLPVGKIANVPHPLVALGLKQAKEVKQKFVTCHYKAVPCLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGE9</accession>
    <name>A0A0A7HGE9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209782.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636202"/>
    <dbReference type="KEGG" id="vg:26636202"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="98" mass="11863" checksum="EEB3A81B6DB2FEAC" modified="2015-03-04" version="1">MIIQIMKPVKSGFWDKSFGKHKFYADRVNSRWELIISQQTKGQMDFVEFYEFDVRPTKRQIRQCKKAFRVYVRASVLRRQRQLAMEPQLVTLDYAKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGF4</accession>
    <name>A0A0A7HGF4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative mobile nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209978.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636398"/>
    <dbReference type="KEGG" id="vg:26636398"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="241" mass="27465" checksum="6089D13A9AAEECD1" modified="2015-03-04" version="1">MNYALIYENLMNRAKSRKLTGYKESHHVVPQCLGGPDTKENRVDLTPEEHYLAHQLLVKINPEHKGLKYAAYMMTISPDGRRQNNKLFGWVKRDYLNNRIQSSGMKGKKHKPESIQLMKDKRALQEITETTKAKISKTKTGVKFTKEALKSFNEKRSANQAWIDSNFRPCKESTKSKIGDANRGRVFDKKTCPHCGKTGAGPNMKRYHFDNCKSKVAKCDLPAFNTNTTPHLDNILPIVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGF5</accession>
    <name>A0A0A7HGF5_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DnaB-like replicative helicase</fullName>
            <ecNumber evidence="1">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VR25_045</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-dependent DNA helicase essential for viral DNA replication and recombination. The helicase moves 5' -&gt; 3' on the lagging strand template, unwinding the DNA duplex ahead of the leading strand polymerase at the replication fork and generating ssDNA for both leading and lagging strand synthesis. Interaction with the primase allows the primase to initiate lagging strand synthesis and fully activates the helicase. Loaded by the helicase assembly factor on replication forks that begin at discrete replication origin sequences, as well as on forks that are created during recombination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer. The homohexamer is a trimer of asymmetric dimers. Interacts with the DNA primase; this interaction forms the active primosome complex, which is composed of 6 helicase and 1 primase subunits and expresses full helicase and primase activities. Interacts (via C-terminus) with the helicase assembly factor; this interaction brings about the rapid assembly of the helicase onto ssDNA. Part of the replicase complex that includes the DNA polymerase, the polymerase clamp, the clamp loader complex, the single-stranded DNA binding protein, the primase, the DnaB-like replicative helicase and the helicase assembly factor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="1"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209787.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636207"/>
    <dbReference type="KEGG" id="vg:26636207"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04155">
        <property type="entry name" value="Helic_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046393">
        <property type="entry name" value="Helic_T4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1194">Viral DNA replication</keyword>
    <feature type="domain" description="SF4 helicase" evidence="3">
        <location>
            <begin position="165"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="431"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="197"/>
            <end position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AIZ02389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="476" mass="53646" checksum="EFBB39B0B18B818F" modified="2015-03-04" version="1">MVETILSQLLFNKEYFVKVWPYLNNTYFEKGPAKTLFNTINEHVKEYQAVPTKTALDIALDGSDLSEVEYEGTKKLLGVLADTPEDQEWLVKETEKYVQKSAMFNATSRIIEIQSNAELPKDKRDKRIPDIGAIPDIMRDALSICFDSALGHDWLNDYEARFQTYLNKSKKVPFRINILNKITKGGVEYGTENVLLAGTNVGKSLGLCSLAADYLQTGHNVLYISMEMAEEVCAKRIDANLLDVSLDDIDEGHISWAEYKSKMEKWRASGTLGTLKIKQYPTGGAHADTFRALLNEYKLKQGFVPDVIIVDYLAICASSRLKTFTENSYGLIKMVAEELRGLAVEKNVVLWTAAQTTRGANVAAEIDMADIAESFGIAHTADFMLGVVETEEFAQMGLQLIKQLKSRYGDKNYYNKFKMGVKKGNQRWYEVDDDSTPKQGPTVKEATGEMNRQAEMNRQTRVNRSDLDDLAAQMKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGG2</accession>
    <name>A0A0A7HGG2_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="4">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nrdB</name>
        <name evidence="9" type="ORF">VR25_246</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209988.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636408"/>
    <dbReference type="KEGG" id="vg:26636408"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030475">
        <property type="entry name" value="RNR_small_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="PTHR23409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00368">
        <property type="entry name" value="RIBORED_SMALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AIZ02590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="392" mass="45227" checksum="9B2C028A3F82D4B1" modified="2015-03-04" version="1">MSTVFNTTPVDVLAEPMFFGSGLGIARYDIQRHKVFEELTEKQLSFFWRPEEVNLMMDGAQFNKLPEHQQNIFTNNLKYQSLLDSIQGRAPAAALAALVSDPSLDTWIQTWTFSETIHSRSYTHIMRNLYTDPAKVFDEILLDDAIMKRAESIGYYYDDVLNKTRQWQNQIAFVELAKETPEVDQRLERAIKQEAIAKRALMKSLYLCLHVINALEAIRFYVSFACTFNFHKNMEIMEGNAKIMKFIARDEQLHLKGTQYILRQLQTGVDGDEWVKIAQECEAEAAAIFMEVNRQEKEWAVHLFKDGGLPGLSVEILNRFIDYLTVSRMKQCGLPCEIVLESTKHPIPWIREYLNSDNVQSAPQEVELSAYLVAQIDNDVDENVLAGFRKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGG7</accession>
    <name>A0A0A7HGG7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209993.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636413"/>
    <dbReference type="KEGG" id="vg:26636413"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="113" mass="13148" checksum="AC144B6CD1AB3458" modified="2015-03-04" version="1">MLAEYTCFAKDDAHPELILEVKVNTLEQKFDWSLYIYPKNIIDVPQKYTLNDKCISGIIGYGTSESKYSLEDIRQSRCAVSYFDTDTIKHLYKLVLDIRKDFTAIKKAVKELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGH2</accession>
    <name>A0A0A7HGH2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RnaseH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rnh</name>
        <name evidence="3" type="ORF">VR25_261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210003.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636423"/>
    <dbReference type="KEGG" id="vg:26636423"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090304">
        <property type="term" value="P:nucleic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036276">
        <property type="entry name" value="T4_RNaseH_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09293">
        <property type="entry name" value="RNaseH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5_3_exonuc_N" evidence="1">
        <location>
            <begin position="19"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="RNaseH_C" evidence="2">
        <location>
            <begin position="188"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="314" mass="36375" checksum="0A4A0535871AFEF8" modified="2015-03-04" version="1">MNLDFLLPEEDRQKEGFQLLDFSQLIMAAAFQEFGKDAGYPKVTTAMTRHLVLNSIRKNIVQFKKLGYTIPIICVDNSKNGYWRRTKSYYYKKNRAKAREESQFDWEGLHAAMHIIIDEMEKYMPYIVMNMDKVEADDHIAVLTKLLTGLGHPVMIVSSDGDFTQLHKFPGVKQWSPMQKKYVKTKSGDALMDCVTKVVKGDKKDNVSSIKVRGDFYYTHEEGERTPPTRAAELEQIALNYYDHDVLKTLLTEEQYNRFCENQLLIDMDFIPTEISASILERYNNYTIPAKSKVYPYFVKSGLSKLTANIAEFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGH6</accession>
    <name>A0A0A7HGH6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Distal long tail fiber assembly catalyst</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210008.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636428"/>
    <dbReference type="KEGG" id="vg:26636428"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="181" mass="21848" checksum="95126D201C637DF4" modified="2015-03-04" version="1">MKIYHFYFDTKEFYKEENYKPVKGLGLPAHSTSKKPLEPKEGYAVVFDERKQDWIYEEDHRGKRAWTFNKEEILINDIGSLIGVTFDEPGEFDLWTDDGWKEDETYKRVMIRNQKIDDLYKEFQVLSNMVEASVADKKEKFYHQNLKRFFALLEKHEHLGGEFPAWPEKEKKSFFKRLFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGI3</accession>
    <name>A0A0A7HGI3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209817.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636237"/>
    <dbReference type="KEGG" id="vg:26636237"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="99" mass="11669" checksum="5CBD2B3D50BD4F87" modified="2015-03-04" version="1">MKRFEEYVATNWTAWDKFGDEWYFHDCDLDPKFFADKEEDLKDIYALSEIHGIKPTVYFSFDDTGFLIQVYVPYATASDEEVIKTWNYQGVISCGPKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGJ5</accession>
    <name>A0A0A7HGJ5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209827.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636247"/>
    <dbReference type="KEGG" id="vg:26636247"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="102" mass="11748" checksum="0D7CAC90AF864FE4" modified="2015-03-04" version="1">MSELSGQTIYLGDGNEDDLEYKLYEYMVALAKEEGIDFAVANPYGENTVVIGGTAYEVQWQYVGLESEEYEEDKHGDWHPVGPWYWDDGEPDFEVSSYWSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGK9</accession>
    <name>A0A0A7HGK9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209842.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636262"/>
    <dbReference type="KEGG" id="vg:26636262"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="150" mass="17142" checksum="F7D859647D406C3A" modified="2015-03-04" version="1">MIINENAWHTKLHDRFYGHYSRPHSLCAYFWKIVWVCFICSVLAGSTIFALTVAGAGVLEQFFVLSTPVGLGLGFILGLATLALILAVAIGVVYCTMSFWAWYDLRKEEKEWERIKAKREGKEIKENLVVQYIKARKSKVCPVIHFEAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGM8</accession>
    <name>A0A0A7HGM8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209862.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636282"/>
    <dbReference type="KEGG" id="vg:26636282"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="87" mass="10120" checksum="65685D2CDF63BB12" modified="2015-03-04" version="1">MIEDIKGYKPHTDDKIGKVNAIKDAEVRLGLMFDALIEEAYILKENETEQQTKEDMDAVQALKYAKQHLKEASMWACRAVFRPEEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGN2</accession>
    <name>A0A0A7HGN2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209867.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636287"/>
    <dbReference type="KEGG" id="vg:26636287"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="87" mass="9574" checksum="59462C47E2AF5EB1" modified="2015-03-04" version="1">MKTYQEFITESAKAPTGAFKVRAFAGDAEDFGTMKRNGYSFFGGDGKEIVTYAKRREIAFVVAGKKVDVDDIEWDFETFGIVSGGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGQ5</accession>
    <name>A0A0A7HGQ5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209892.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636312"/>
    <dbReference type="KEGG" id="vg:26636312"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="141" mass="15880" checksum="D35AA483DEA1D352" modified="2015-03-04" version="1">MNFLTLTSAFSVTRITNKMVADEVCEICIREDALIHLTSTQIVAIAKSLNSELKVNTKQSKESIIELIQAEMIEFPIEEVKEEKIQSKSGNARDICFQAFAEIDMNDNAARRALIDVLVTTHDIKKTVVQSYASNFRKAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGU7</accession>
    <name>A0A0A7HGU7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209932.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636352"/>
    <dbReference type="KEGG" id="vg:26636352"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="93" mass="10904" checksum="AB0CF59519549975" modified="2015-03-04" version="1">MNKVSFLRNTFKNLEIEVVALVNKYPNGVNGNALNKLVKKYENLAYDTDFWWNGNYSTHTKDKSGNWLKLQENSVNFRDLIKRRVEVHLNGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGW3</accession>
    <name>A0A0A7HGW3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Baseplate hub subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209947.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636367"/>
    <dbReference type="KEGG" id="vg:26636367"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024364">
        <property type="entry name" value="Baseplate_phage_T4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12322">
        <property type="entry name" value="T4_baseplate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="207" mass="23526" checksum="486F1AD3114E80A0" modified="2015-03-04" version="1">MTYEFIVQIKNKTINCRAFTLREYKDLLQAKLEKRMEPAIIELLNKCTDAKGLNKQEAELLLINLWANSLGAVNVEHTWVCECGKEQDIPVTISRASIVDESEVIRDFGSFKIKFRYPGLFEDGDKGKMIACCIEYIITEGGERIVVDDLNEAEIEDLYNAITLDDINALTEELLKPQVQMAIPISCECGAHSVHVIKGLKEFFKFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGY2</accession>
    <name>A0A0A7HGY2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Baseplate subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209952.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636372"/>
    <dbReference type="KEGG" id="vg:26636372"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024389">
        <property type="entry name" value="Gp48_T4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11091">
        <property type="entry name" value="T4_tail_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="366" mass="39839" checksum="E56A4C37DE79C456" modified="2015-03-04" version="1">MKVKELDFDLDIAGLFNGGSKTSAGQSKAAQTQATIVAQYPAERASGNDSSDDMRVNDLYKNGLLFTAYNFSSRTSPELRSDRSSQLTSLKKVSNGASFNPVKSLTSFAKSKLTGSGSTGKSFDSNAVANILLPRSKSDVESVSHRFNDVGESLVTKGGGSATGILSNIASTAVFGALESVTNGVMADHGEQIYTTARSMYAGPDNRTKVYTWEMTPRSAQDLIQIVKIYEIFNYYSYGETGKSSFASELKDKIDTWYKSTFKKEAIDNFDGKLLGEEITSFLTNVLVVSNPTIWYIRNFGDTSSYDGRGELFGPCQIQSIRFDKSPDGHFGGLAIAPNLPSTFVLEITFREIITLNRGSLYAEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGZ8</accession>
    <name>A0A0A7HGZ8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209972.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636392"/>
    <dbReference type="KEGG" id="vg:26636392"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="112" mass="12560" checksum="963EE07B13A3C571" modified="2015-03-04" version="1">MISLVEAITTALQEDKDGDHRGLSDGAIQFIRALLMNDTLFKSISPADYDGVLLTMLPVEIGNSLSGVVFFDKKKRFKDGYGILTSRVKSITKLRHELYRVETDKSAYIMVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HH19</accession>
    <name>A0A0A7HH19_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Long tail fiber distal subunit adhesine</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VR25_265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210007.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636427"/>
    <dbReference type="KEGG" id="vg:26636427"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011083">
        <property type="entry name" value="Phage_tail_collar_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037053">
        <property type="entry name" value="Phage_tail_collar_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07484">
        <property type="entry name" value="Collar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Collar" evidence="2">
        <location>
            <begin position="820"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="922"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="988"/>
            <end position="1013"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="1067" mass="113621" checksum="9933C7CDC0F6C233" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HH34</accession>
    <name>A0A0A7HH34_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA endonuclease IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">denB</name>
        <name evidence="1" type="ORF">VR25_290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210032.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636452"/>
    <dbReference type="KEGG" id="vg:26636452"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="197" mass="22445" checksum="AFA9D8C328164903" modified="2015-03-04" version="1">MIQKSKTWEHLKKMPSFLYTKEDLTPESLQKIVDTARYSLSKDPGQDREQVMQRCMVATMAEQAIAKWTSGFLCGGDEDYNNPFSFAFDVVSQEGVRIEVKTHQSGSKWISVHTGHQGDYPHGYGVNLGPFMQHKLADLMIMFNVKETIKGYRFKPKFLAGPGAFVPESGLVQKSQGDGWYLRSCSEEKFPYHRFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCD6</accession>
    <name>A0A0A7HCD6_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sliding-clamp-loader small subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Clamp loader gp62 subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Forms the sliding-clamp-loader together with the small subunit. The clamp loader holds the clamp in an open conformation and places it onto the DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The sliding-clamp-loader consists of 4 large subunits and 1 small subunit. Interacts with the sliding clamp; this interaction allows the sliding-clamp-loader to open the sliding clamp. Part of the replicase complex that includes the DNA polymerase, the polymerase clamp, the clamp loader complex, the single-stranded DNA binding protein, the primase, the helicase and the helicase assembly factor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tevenvirinae sliding-clamp-loader small subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209795.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636215"/>
    <dbReference type="KEGG" id="vg:26636215"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04163">
        <property type="entry name" value="T4_Clamp_Loader_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031868">
        <property type="entry name" value="Phage_clamp_gp62"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16790">
        <property type="entry name" value="Phage_clamp_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1194">Viral DNA replication</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="192" mass="22200" checksum="8F90C8CFBA9E938E" modified="2015-03-04" version="1">MAVSLFDDDVQLNEHEVAWKSRDFNKIQELSDSYKEKAENELFAILNDVTVSKKPRCLIQSENYNKFWLDNALSQHVDCIMQVNVMNLIGAGLTDQQHYNYLLHAVPQGKRYGKWAKAEPDAVNVQLVIKLLMKYYTINADDALMYLETLKVKGSLKDVLKKTKGLVTDEFLKTVTSNVKEQKEIKKQILEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCE5</accession>
    <name>A0A0A7HCE5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209805.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636225"/>
    <dbReference type="KEGG" id="vg:26636225"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022558">
        <property type="entry name" value="DUF2654"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10849">
        <property type="entry name" value="DUF2654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="103" mass="11941" checksum="3CE51C78664BA15B" modified="2015-03-04" version="1">MQAPDISQLTDKQIEEAQERLEEANALEATSQATKILKKNAREIERLNKHAQGAVLENNFEAYKYALVKLRGIYRQPVTEDLIKLMWETTRKQIWEIVNGISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCG5</accession>
    <name>A0A0A7HCG5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_004</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209746.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636166"/>
    <dbReference type="KEGG" id="vg:26636166"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="50" mass="5891" checksum="6643B2580B3F51B3" modified="2015-03-04" version="1">MTKYWITLATGEYGFLWAEKKPLFAEFVTITCETWEGETFIAYGQVYKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCG8</accession>
    <name>A0A0A7HCG8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209825.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636245"/>
    <dbReference type="KEGG" id="vg:26636245"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="49" mass="5971" checksum="49BD1FCE30A63F2D" modified="2015-03-04" version="1">MDYVIKPWYTARWETVEPEEPVYNGSETEYNEPSNNELIDMEFGYEYQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCH3</accession>
    <name>A0A0A7HCH3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209830.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636250"/>
    <dbReference type="KEGG" id="vg:26636250"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="80" mass="9468" checksum="817E2A3307E073DA" modified="2015-03-04" version="1">MAKRKEYLETADKAVRELTLAYYKEHGKFPDSYSVLKSALTRSYNNMRSEVYDIMDKHKEQTGQYSDYTETFKQVLGIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCH9</accession>
    <name>A0A0A7HCH9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ADP-ribosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">modB</name>
        <name evidence="1" type="ORF">VR25_019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209761.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636181"/>
    <dbReference type="KEGG" id="vg:26636181"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="186" mass="21488" checksum="FDE96A4AE40B5F51" modified="2015-03-04" version="1">MNIIKSDTEPNQLKFSEMEIASLFECRTSKVDKTLHSNVNSIIKSRLSVPDTVLYRGVTQQEIDLLDEAKESMQPFEFGRITSFTEDYGIARDFAAMEYVTRTIVRLNQTEAFCYHDAMRKLALDVPLKFFNTASGSKQEATLRREEYMDMIDSELEWFVPVDQKFVIVDAGFVGDYYVLDCVQEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCI3</accession>
    <name>A0A0A7HCI3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_098</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209840.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636260"/>
    <dbReference type="KEGG" id="vg:26636260"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="74" mass="8893" checksum="7C09BCA26A86495C" modified="2015-03-04" version="1">MTTTIPIIVNEEMKVFLSYGRPNKGRRWYLEAVCRETGRRINNKYICKPTPKQTREFANWAIDDIRFHNFWSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCI7</accession>
    <name>A0A0A7HCI7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209845.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636265"/>
    <dbReference type="KEGG" id="vg:26636265"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="31" mass="3699" checksum="F4A71AF972E8E6CA" modified="2015-03-04" version="1">MIYYLEPWAWLIMAVGPVLIGLFFSWLARKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCJ2</accession>
    <name>A0A0A7HCJ2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_108</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209850.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636270"/>
    <dbReference type="KEGG" id="vg:26636270"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043876">
        <property type="entry name" value="DUF5856"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19174">
        <property type="entry name" value="DUF5856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="127" mass="14588" checksum="3789F053700A352C" modified="2015-03-04" version="1">MKFDDFVTGRGSEVDSYIGWLLVSLAYFKSAHLETKSYARHKAYDFYFTEIQGPLDQFSEQWLGYSGKQYKAALPSASDLPKDTILFLDEMIKSSERVYKVVPKAIQSTLDDIVGVFFQTKYLLTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCJ5</accession>
    <name>A0A0A7HCJ5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_113</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209855.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636275"/>
    <dbReference type="KEGG" id="vg:26636275"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="60" mass="6998" checksum="988CAC19D04DB9BE" modified="2015-03-04" version="1">MSLSISQKSRLFELIHELLEENSGMQSYDEWGPVSAEDYEKIAEQFDKKENELIAYVNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCJ9</accession>
    <name>A0A0A7HCJ9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">regB</name>
        <name evidence="1" type="ORF">VR25_118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209860.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636280"/>
    <dbReference type="KEGG" id="vg:26636280"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019653">
        <property type="entry name" value="T4_endoribonuclease_RegB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10715">
        <property type="entry name" value="REGB_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="152" mass="17665" checksum="D73C1420AD65FE0A" modified="2015-03-04" version="1">MTTIDSSVYIRRNKLRRIFETEFLKINNAINKACKEAGLEAFFIKYSPHLLDRAIQREIDEQYVFDLFGKITPHVKEIVEFLEMKPLPEVEAQIDPNVNYRPLRLEITDKNLWLGMTVNPALPGKSPTMCCRMAFVNSNRLEGKISTKVIYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCK1</accession>
    <name>A0A0A7HCK1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209786.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636206"/>
    <dbReference type="KEGG" id="vg:26636206"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="100" mass="11238" checksum="34F90DCAC73D3EA3" modified="2015-03-04" version="1">MFNQTDMNRYYFGQFARRDETCAALIASGIQTGKLIKLKSDVHPSAVRSSLREYLLAGGEVFVIAEPFVNVCDDYTISVTVMHPTTGKIRCLTMHNYELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCK4</accession>
    <name>A0A0A7HCK4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_123</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209865.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636285"/>
    <dbReference type="KEGG" id="vg:26636285"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="175" mass="20400" checksum="F80CD8E4B507206D" modified="2015-03-04" version="1">MKFLTPIYLTLMHAFAERAIERLDSDQYTWYEPASRMQEFGTLRLDGGRQTGKTSALAQFAADWVSKGNDVIVMSSSSHRSREICDIIKRVSKAQPHLQVERPGFVVYDTVRSFLDEDNFHKYRGLRFTRLLIIIEEPIRLPAMDKFYEAYQVMMNKFMCQGDKPLPLFFVIGMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCK8</accession>
    <name>A0A0A7HCK8_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sliding-clamp-loader large subunit</fullName>
            <ecNumber evidence="1">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Clamp loader gp44 subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VR25_054</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Forms the sliding-clamp-loader together with the small subunit. Functions as an ATPase enzyme. The clamp loader holds the clamp in an open conformation and places it onto the DNA. 4 ATP molecules must bind to the sliding-clamp-loader before the latter can open the sliding clamp. ATP hydrolysis triggers the detachment of the sliding clamp from the sliding-clamp-loader, freeing the sliding clamp to track along DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The sliding-clamp-loader consists of 4 large subunits and 1 small subunit. Interacts with the sliding clamp; this interaction allows the sliding-clamp-loader to open the sliding clamp. Part of the replicase complex that includes the DNA polymerase, the polymerase clamp, the clamp loader complex, the single-stranded DNA binding protein, the primase, the helicase and the helicase assembly factor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tevenvirinae sliding-clamp-loader large subunit family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="1"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209796.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636216"/>
    <dbReference type="KEGG" id="vg:26636216"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04162">
        <property type="entry name" value="T4_Clamp_Loader_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046388">
        <property type="entry name" value="T4_Clamp_Loader_L"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1194">Viral DNA replication</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="48"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="18"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="59"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="325" mass="36253" checksum="A4F3F68FA4F41E68" modified="2015-03-04" version="1">MATVINGLTVNESDFMWEQKYRPGTLSECILPAHDKETLEAIVKKGLIPNLILVSSSPGTGKTTVAKAMCADTNSDMLFVNGSDCRIDFVRNELTRFASSKSIEGRRKVIVIDEFDRAGLAESQRHLRSFMEAYSSNCSIIMTANNIDGIITPLQSRCRVIKFGESTDEDRTSMLKQMIHRSVAICKNEGVEIEDLKVVAALVKHNFPDLRKTINELDRYSAKGVIDSGILSIVTNNRTPIDDVIDALKDRNFKVLRGLAPKFANDYSNFIAKLADEMYGKLTGASIIRMYEIVGENNQYHGLAANTEVHLTYLFAQLAGEMKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCM8</accession>
    <name>A0A0A7HCM8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209895.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636315"/>
    <dbReference type="KEGG" id="vg:26636315"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="61" mass="6669" checksum="D07E2B710FEAEA07" modified="2015-03-04" version="1">MKRCELIRNVTALVAVTAFGFSMFAGFMLNMLSTSENIISLVVAFLIGSISFVMDKMSKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCN2</accession>
    <name>A0A0A7HCN2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209900.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636320"/>
    <dbReference type="KEGG" id="vg:26636320"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="151" mass="16991" checksum="BEC35B22EDB49AD5" modified="2015-03-04" version="1">MTLNEVSEGLYVAAKFSELTLDALENLQRSLKVPNPVPREKFHSTICYSRVNIPYVVASGSFEVANSGHLEVWKTDDGSTLVLVLDSDYLSCRHMYARAIGATHDFPDYTPHITLSYNVGPLTYKGEVQIPVVLDREYKEPLKLNWSADLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCN7</accession>
    <name>A0A0A7HCN7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA end protector protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_163</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209905.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636325"/>
    <dbReference type="KEGG" id="vg:26636325"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="275" mass="31581" checksum="6651E23F831C7594" modified="2015-03-04" version="1">MSIFTFINESADKPGPKPSKSEQQWVEIGVEFYTAKEKGMTSKKFAEEKGINYSTFTKSMSRYHSRIQTAYKVSKLKKKPAGKLTKTERQLIMVNSFRKSIRDKIANEGAASNTKSARWFAETIKKAVRGHVTAKPQPGKIYAYIYDAKHKDTLPYWDKYPLIIYLGLGKHNLMYGLNLHYIPPKARQEFLEELLKQYANTPTITNKTHLKIDWSKVKGFKGADQMIKAYIPGNIKGTITEIKPSDWANVVLLPLQQFFSKGKRFSSQKVWRNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCP1</accession>
    <name>A0A0A7HCP1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209910.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636330"/>
    <dbReference type="KEGG" id="vg:26636330"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008727">
        <property type="entry name" value="PAAR_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05488">
        <property type="entry name" value="PAAR_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="97" mass="10192" checksum="50C92BDBD1700DF0" modified="2015-03-04" version="1">MAGLSFNQCVTAGHEAWPPTVINATQGKVFTGGIPVLVAGDPITEHTEIKKPYETHGGVTQPRTPKVFVTGKKAVQMADPISCGDTVAQASSKVFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCP4</accession>
    <name>A0A0A7HCP4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_094</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209836.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636256"/>
    <dbReference type="KEGG" id="vg:26636256"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="174" mass="20161" checksum="9CA956A1506F8980" modified="2015-03-04" version="1">MEAKSIFNLINYNNGNFKSEAQSKFFNDVACAGEITVSGGQTYKNAWNWIVNVDSVGIIDVYKNTNKNRSLFWSRETNAEYQAARAKKNMPTESDVQNIKSDIQYYDGLIAEQQAVLDKFNEIKACKEIPEFMRESVNEQYNLTSERIETYTKQRAERQVLLQKFEKRLKTVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCP6</accession>
    <name>A0A0A7HCP6_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Baseplate wedge protein gp10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Baseplate protein. Involved in the tail assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotrimer; disulfide-linked. Heteromultimer with gp7; a gp10 molecule is disulfide-linked to gp7 and the other two remaining gp10 molecules form a disulfide bond.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Present in the baseplate.</text>
    </comment>
    <comment type="induction">
        <text evidence="1">Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the T4likevirus baseplate wedge protein gp10 family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209915.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636335"/>
    <dbReference type="KEGG" id="vg:26636335"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098025">
        <property type="term" value="C:virus tail, baseplate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019076">
        <property type="term" value="P:viral release from host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098003">
        <property type="term" value="P:viral tail assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04106">
        <property type="entry name" value="BP10_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008987">
        <property type="entry name" value="Baseplate_struct_prot_Gp9/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034695">
        <property type="entry name" value="BP10_T4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036240">
        <property type="entry name" value="Gp9-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027411">
        <property type="entry name" value="Gp9/Gp10_mid_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07880">
        <property type="entry name" value="T4_gp9_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50017">
        <property type="entry name" value="SSF50017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0426">Late protein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1226">Viral baseplate protein</keyword>
    <keyword evidence="1" id="KW-1188">Viral release from host cell</keyword>
    <keyword evidence="1" id="KW-1245">Viral tail assembly</keyword>
    <keyword evidence="1" id="KW-1227">Viral tail protein</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <feature type="disulfide bond" description="Interchain (with GP7); alternate" evidence="1">
        <location>
            <position position="555"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Interchain; alternate" evidence="1">
        <location>
            <position position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="603" mass="66298" checksum="FB844530BEE45E2B" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCQ6</accession>
    <name>A0A0A7HCQ6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prohead core protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209930.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636350"/>
    <dbReference type="KEGG" id="vg:26636350"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="272" mass="29831" checksum="5A3D75D9CF0C28CD" modified="2015-03-04" version="1">MLKEQLISEAQNIDASVALDSIFESVNLSPEAKATFGTVFEATVKQHAIKLAESHIHAIAEKAEEEVEKNKEESDEKAEKKLKESAAKFLDHVAKEWLAENKLAVDRGIKADLFESMFTGMKELFVEHNVVVPEESVDVVAEMQEELEEQKAETASLFEEVSKRDAYINYVQREVALTEATKDLTESQKEKVGSLVEGMDYSDAFGTKIGAIVEMVKGQVDTAEKPITEAAINNSVDDAAALNYISEAVEEKGAKPTLSFADLSALAASRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCQ8</accession>
    <name>A0A0A7HCQ8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209856.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636276"/>
    <dbReference type="KEGG" id="vg:26636276"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="70" mass="8572" checksum="316C061B82021F05" modified="2015-03-04" version="1">MKAHYPHPFDPKNKATIIRHWSETRITKCPIKSPHNVDKWYIGEYVEYTFIDKNKRVQHVDEYCLKVQWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCR3</accession>
    <name>A0A0A7HCR3_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA ligase 2</fullName>
            <ecNumber evidence="4">6.5.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Rnl2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rnlB</name>
        <name evidence="7" type="ORF">VR25_193</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Repairs 3'-OH/5'-PO4 nicks in duplex RNA or RNA:DNA hybrid in which the broken 3'-OH strand is RNA. The nick ligation reaction entails three nucleotidyl transfer steps. In the first step, the RNA ligase reacts with ATP in the absence of nucleic acid to form a covalent ligase-AMP intermediate and release pyrophosphate. In step 2, the ligase-AMP binds to the nicked duplex nucleic acid and transfers the adenylate to the 5'-PO4 terminus to form an adenylylated nicked intermediate. In step 3, the RNA ligase directs the attack of the nick 3'-OH on the 5'-phosphoanhydride linkage, resulting in a repaired 3' - 5' phosphodiester and release of AMP.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="4">Binds 2 magnesium ions that may perform the catalytic activity via a two-metal mechanism.</text>
    </comment>
    <comment type="domain">
        <text evidence="4">The adenylyltransferase domain in the N-terminus performs step 1 and step 3 reactions. The C-terminus domain is required for step 2 of the ligation pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNA ligase 2 family.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.3" evidence="4"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209935.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636355"/>
    <dbReference type="KEGG" id="vg:26636355"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003972">
        <property type="term" value="F:RNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042245">
        <property type="term" value="P:RNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04150">
        <property type="entry name" value="RNALIG2_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012647">
        <property type="entry name" value="RNA_lig_RNL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021122">
        <property type="entry name" value="RNA_ligase_dom_REL/Rnl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041948">
        <property type="entry name" value="Rnl1/2_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040609">
        <property type="entry name" value="Rnl2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044263">
        <property type="entry name" value="Rnl2_vir"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09414">
        <property type="entry name" value="RNA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18043">
        <property type="entry name" value="T4_Rnl2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02307">
        <property type="entry name" value="RNA_lig_RNL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0692">RNA repair</keyword>
    <feature type="domain" description="RNA_ligase" evidence="5">
        <location>
            <begin position="29"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="T4_Rnl2_C" evidence="6">
        <location>
            <begin position="252"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Adenylyltransferase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="4">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AIZ02537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="334" mass="37792" checksum="76C91108FCD3DB2E" modified="2015-03-04" version="1">MFKKYNSLENHYNNKFIEKIRLQGFTSGEWVAREKIHGTNFSLIIEQDNVTCAKRTGPILPAEDFYGYEIVLKNYADSIKTVQRLLQDINYQSYQIYGEFAGAGIQKNVDYGDKDFYVFDIRVTKEDGSESVLTDSLMEAFCIIHKFKVAPRLATGSFEDLIKLPNDLDSVVPDYNFTVDNAGLTTANTTDFDAKVEGKVFTAEGYVLKPDTPAWLPNGERVAIKCKNSKFSEKKKSDKPIKAAVVLSQEDLDILWKFTDYVTVNRINNVISKIGEVTPKDFGKVMGLTVQDILEEAGREGLELTQTENPVEVKKQLIANVRDTLRHVWIALIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCR4</accession>
    <name>A0A0A7HCR4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209861.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636281"/>
    <dbReference type="KEGG" id="vg:26636281"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="101" mass="11801" checksum="C6066D7476F6FE54" modified="2015-03-04" version="1">MAQINSGFGYELSTASQRRINDSNPFGFTSKQPKIQSLDDFQEVIRKAFQDYGNYLKEDSNDCLEEDEIAYYEQRLEQLKNLHAVRAEVSQSLNKLIRFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCS4</accession>
    <name>A0A0A7HCS4_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Lysozyme</fullName>
            <ecNumber evidence="2 7">3.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">e</name>
        <name evidence="8" type="ORF">VR25_129</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of (1-&gt;4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glycosyl hydrolase 24 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.17" evidence="2 7"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209871.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636291"/>
    <dbReference type="KEGG" id="vg:26636291"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002196">
        <property type="entry name" value="Glyco_hydro_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023347">
        <property type="entry name" value="Lysozyme_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001165">
        <property type="entry name" value="T4-type_lysozyme"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00959">
        <property type="entry name" value="Phage_lysozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00684">
        <property type="entry name" value="T4LYSOZYME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="5 7" id="KW-0081">Bacteriolytic enzyme</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1188">Viral release from host cell</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AIZ02473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="164" mass="18814" checksum="5EAF99A103602CAD" modified="2015-03-04" version="1">MNIFEMLRIDEGCKLDLYKDTEGYWTIGIGQLITKNPSKDVARAELDKLMGRVCNGRITQVEAETLFNRSVEKARASVMRNAKLKPVYDSLDEVRRCALINMVFQMGEAGVAGFTNSLRLLQQKRWDEAAVNLAQSKWYKQTPNRAKRVISTFKTGTWKVYENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCV4</accession>
    <name>A0A0A7HCV4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chaperone for tail fiber formation</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209901.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636321"/>
    <dbReference type="KEGG" id="vg:26636321"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020159">
        <property type="entry name" value="Phage_Gp57"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17594">
        <property type="entry name" value="GP57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="76" mass="8247" checksum="D34BCEFA0338DD60" modified="2015-03-04" version="1">MSEQTIEQKLQAEIVALKSRILDTQDVAAQAQQESRILQDALSKIAARLGITGDQIQIEDLIAAVPDLTAESADEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCY8</accession>
    <name>A0A0A7HCY8_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Portal protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">gp20</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Forms the portal vertex of the capsid. This portal plays critical roles in head assembly, genome packaging, neck/tail attachment, and genome ejection. The portal protein multimerizes as a single ring-shaped homododecamer arranged around a central channel. Binds to the terminase subunits to form the packaging machine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homododecamer. Interacts with the large terminase subunit. Interacts with the major capsid protein. Interacts with the capsid vertex protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Located at a unique 5-fold vertex of the icosahedral capsid.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tevenvirinae portal protein family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209926.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636346"/>
    <dbReference type="KEGG" id="vg:26636346"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019028">
        <property type="term" value="C:viral capsid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099000">
        <property type="term" value="P:viral genome ejection through host cell envelope, contractile tail mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019072">
        <property type="term" value="P:viral genome packaging"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019076">
        <property type="term" value="P:viral release from host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04114">
        <property type="entry name" value="PORTAL_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010823">
        <property type="entry name" value="Portal_Gp20"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07230">
        <property type="entry name" value="Portal_Gp20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0118">Viral capsid assembly</keyword>
    <keyword evidence="1" id="KW-1242">Viral contractile tail ejection system</keyword>
    <keyword evidence="1" id="KW-1171">Viral genome ejection through host cell envelope</keyword>
    <keyword evidence="1" id="KW-0231">Viral genome packaging</keyword>
    <keyword evidence="1" id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword evidence="1" id="KW-1188">Viral release from host cell</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <keyword evidence="1" id="KW-1160">Virus entry into host cell</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="524" mass="61326" checksum="A1A6C96692281C29" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCZ0</accession>
    <name>A0A0A7HCZ0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209980.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636400"/>
    <dbReference type="KEGG" id="vg:26636400"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="99" mass="11071" checksum="37F5466988CDB190" modified="2015-03-04" version="1">MKELLENYIKCSDHYVDLCYGLKISEHDEVAGQALDNAGKALRKAAKAQGVDMSELKNHLIMFISANTRRKSSNKAVAELNEGRVELRIQLLKTLLGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCZ4</accession>
    <name>A0A0A7HCZ4_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Major capsid protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Major head protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">gp23</fullName>
        </alternativeName>
        <component>
            <recommendedName>
                <fullName evidence="1">Mature major capsid protein</fullName>
            </recommendedName>
            <alternativeName>
                <fullName evidence="1">gp23*</fullName>
            </alternativeName>
        </component>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Major capsid protein that self-associates to form hexamers, building most of the capsid in association with pentons made of the capsid vertex protein and one dodecamer of the portal protein.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer. Interacts with the portal protein. Interacts with the capsid vertex protein that forms pentamers.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Major capsid protein</molecule>
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Part of the icosahedric capsid shell of the immature virion.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Mature major capsid protein</molecule>
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Part of the icosahedric capsid shell of the mature virion.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">A proteolytic cleavage gives rise to the mature major capsid protein during virus maturation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tevenvirinae major capsid protein family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209931.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636351"/>
    <dbReference type="KEGG" id="vg:26636351"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019028">
        <property type="term" value="C:viral capsid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04117">
        <property type="entry name" value="CAPSID_H_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038997">
        <property type="entry name" value="CAPSID_Myoviridae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010762">
        <property type="entry name" value="Gp23/Gp24_T4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07068">
        <property type="entry name" value="Gp23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="1" id="KW-0426">Late protein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_5023386128" description="Major capsid protein" evidence="1">
        <location>
            <begin position="1"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023386129" description="Mature major capsid protein" evidence="1">
        <location>
            <begin position="64"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage" evidence="1">
        <location>
            <begin position="63"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="519" mass="55633" checksum="AE2413C474DE2960" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCZ5</accession>
    <name>A0A0A7HCZ5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209985.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636405"/>
    <dbReference type="KEGG" id="vg:26636405"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039653">
        <property type="term" value="P:suppression by virus of host transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020367">
        <property type="entry name" value="Host_transcript_inhib_Alc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17527">
        <property type="entry name" value="ALC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="77" mass="8817" checksum="D124FC5506083F6B" modified="2015-03-04" version="1">MLNLISNDRVTKAYGDRNDGIYVYKGDRRIGFITDLKAKLLKELKDQTGDSGFRARAKKKDERLGANSFGPRGYNRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD07</accession>
    <name>A0A0A7HD07_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inhibitor of prohead protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">inh</name>
        <name evidence="1" type="ORF">VR25_199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209941.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636361"/>
    <dbReference type="KEGG" id="vg:26636361"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016594">
        <property type="entry name" value="Phage_T4_inh"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012159">
        <property type="entry name" value="Inh_gp21_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="226" mass="25593" checksum="07A2541525A23536" modified="2015-03-04" version="1">MIDKNYIEEIRVLEKKEAKEKLAEYASSLGVDVKKTKTFDNMLIDLEAGLQAFADMPMPDDNEGLSITDLINADDELSGGKFEGEESAKPEAVLLFDAPEAPVEVVEVTQEVVPESEVKLVEIEVPFVSEDFEEAVAQIIEAETPKFTLPKNFSPNLLMLGKAPGYCTLPWWIYQWIKETPDWKERPTSFTHASAHQTLFSLIYYINRDGSILIRETRNSSFIRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD09</accession>
    <name>A0A0A7HD09_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Long tail fiber protein hinge connector</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210005.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636425"/>
    <dbReference type="KEGG" id="vg:26636425"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039477">
        <property type="entry name" value="ILEI/PANDER_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15711">
        <property type="entry name" value="ILEI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ILEI" evidence="1">
        <location>
            <begin position="57"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="378" mass="41940" checksum="AD11F3ABF753EB3E" modified="2015-03-04" version="1">MEKFMAEFGQGYVQVPVLSENNAVRYKLSIAGTCTKSPNYPYVKFQDEAFGPQNFQNGLNLIEINPVTNTITATKNYGFTKDYDVISQAFVTYINSIPAGRIVCLISQGKLNASQTLIDWFRAHGSTAFPDKWLIDQVDTSYAAFYITGRNAIVKEHVLYNDGVTVEDVLTPLEMVYDDFADVGGTGFPLRIVEDENTYYSNVTQEIKRFPTDDPITPVATYNMAPGDTFYLKFQLTYDQALKDLGTTQMSVRFFTGQTMIQSNDYDIPATGQASPPAGAWMTFERYVVVPPNADGFTLYARKTVTTGQGGVRNIFFTEIARQETQAKSAEIGVNGIRMVVAGEPGNMGNVIAQLNDKNATRSSQAGFVFAAEFREKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD27</accession>
    <name>A0A0A7HD27_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protector from prophage-induced early lysis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rIIB</name>
        <name evidence="1" type="ORF">VR25_293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210035.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636455"/>
    <dbReference type="KEGG" id="vg:26636455"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="317" mass="35896" checksum="20DC398F114F2D9D" modified="2015-03-04" version="1">MYNIKCVSEYEQKQIVSLYASGNYTQQELADWYNISVDTIRRVLKNDKEFKPSEVVITGNITVTVPNEPQVVPVTDTIGGSRPEIVWNASSKFVSITEGRTVWNATKDHKHFDAIIQALKESRFDDAIEFISIKAAVQKYVKGDVRIEGGSLFYQGIELRSGLVTRIINSMQNGEDFEFYLPFLENLLENPSEKAVQRLFDFLVANDIEITEDGHFIAWKMVRSTYKDCHSNTFDNSPGQYVKMPRSRVNDNDEQTCSTGLHVCSKGYIGSGFGHGDGRIVSCKVHPRDVVSIPVDYNDSKMRVCGYLVLDDVTEQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD51</accession>
    <name>A0A0A7HD51_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209956.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636376"/>
    <dbReference type="KEGG" id="vg:26636376"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="1">
        <location>
            <begin position="135"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="510" mass="57652" checksum="35F82AE8ECE66411" modified="2015-03-04" version="1">MILDILNEIAATDSTKEKQAILESYSENETLKRVYRLTYSKGIQFYIKKWPKPGTTTQSFGMLNIDDMLDFIEFTLAPRKLTGNAAIEELSGYIADGKKDDVEVLRRVMMRDLECGASVSIANKVWKGLIPEQPQMLASSYDEAGIAKNIKFPAFAQLKADGARCFAEVRGDELDDVRLLSRAGNEYLKLDLLKKELIEATREARERHPEGVLIDGELVYHEQKVAPQNDGLGFLFGDTEQAETQIESAESRTKSNGLANKSLKGTITAVEAAGMKFQVWDYVPLIEVYSDVKILNPLKYDVRFAVLEKMIADNVVLHGYDRMILIENHVVNNLEEAKAIYKKYIALKLEGIILKNTAAPWENKRSKNMYKFKEVIDIALEIIGFYEHEKDPNKIGGVVLQSSCGKIVTNCGSGFKDTTQVKDPKTKKWTIIPIDERHEMDREALMIKARKGELVGMIADCECNGWLTSETRKDNTVKLFLPIIKGFRFDKDKADTFEEVFGDWSQTGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD64</accession>
    <name>A0A0A7HD64_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Deoxycytidylate deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cd</name>
        <name evidence="8" type="ORF">VR25_229</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209971.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636391"/>
    <dbReference type="KEGG" id="vg:26636391"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016473">
        <property type="entry name" value="dCMP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="PTHR11086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006019">
        <property type="entry name" value="dCMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AIZ02573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="193" mass="21369" checksum="864DDF4FB88DDCB7" modified="2015-03-04" version="1">MKPTTVLQIAYLVSQESKCCSWKVGAVIEKNGRIISTGYNGSPAGGVNCCEHAEEQGWLLNKPKPVLVPGHKPECVRFSKVDRFVLAKAHREEHSAWSKNNEIHAELNAILFAARMGSSIEGATMYVTLSPCPDCAKAISQSGIKKLVYCETYDKNIPGWDDILKNAGIEVFNVPKRSLDKLNWENINEFCGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD68</accession>
    <name>A0A0A7HD68_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_234</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209976.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636396"/>
    <dbReference type="KEGG" id="vg:26636396"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="71" mass="8292" checksum="C2630343EBD23E54" modified="2015-03-04" version="1">MYDKHDEIKEEAYGFLNKLAGQGMSPALINELVKIRNDMNTRYKGEYHVEFAPLVEITDRFVVDVRVHTVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD81</accession>
    <name>A0A0A7HD81_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydrofolate reductase</fullName>
            <ecNumber evidence="1">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">frd</name>
        <name evidence="6" type="ORF">VR25_249</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="1"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209991.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636411"/>
    <dbReference type="KEGG" id="vg:26636411"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="PTHR48069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="5">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AIZ02593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="193" mass="21588" checksum="785046B68945F07A" modified="2015-03-04" version="1">MIKLVFAYSPTKTVDGRDENAFGLDDGLPWGHIKKDLQNFKARTKNSIVLMGAKTFESLPSILKGRFHVVVADPARPYPVTKAGELAGGYITWANYLKLVSGEKISISAPDAPAQMLISSENYICVIGGKSLLEAAAPYADEIVMTKIYKKHRVNSTVQLDSDFLYDISKREMLETHWYKIDEVTHITETVYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD89</accession>
    <name>A0A0A7HD89_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Long tail fiber protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_264</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210006.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636426"/>
    <dbReference type="KEGG" id="vg:26636426"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="219" mass="23966" checksum="CD0F3052B907F89C" modified="2015-03-04" version="1">MADLRVGSTTGGSVIWHQGNFPLTPVSNDVFYKTYKVYTEFNKPQAADNDFVSKAAGGTYLNTVGFDKDLQFKDTDGYWVKLGRKVNNSPMSATYSFSFRMSKGMGLETSDGTPFVIFDPSTVVGANRLTVMGDILGRQIKDESGRVFSPGNTPSKAQVGLSDVDNAKQVQINNSNIQSMAGVLSAPNFISRNPGTLNEHVPRIDQVVLRGTYEDFGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD94</accession>
    <name>A0A0A7HD94_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_269</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210011.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636431"/>
    <dbReference type="KEGG" id="vg:26636431"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="54" mass="6470" checksum="8E755C5C3292CA72" modified="2015-03-04" version="1">MSHNLENTITGQRTHEQACFEEFLGADFKFQEPIEDMYQTYVVQMENHVYNPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD95</accession>
    <name>A0A0A7HD95_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210016.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636436"/>
    <dbReference type="KEGG" id="vg:26636436"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="114" mass="12967" checksum="B9CE26B9A70F521E" modified="2015-03-04" version="1">MNKLNIVNELRACVEPTQEGWDVWYHGAYLGTIIKVKAGLYLIIRENSEFPNGVAPGGIRKNFMAAIGAFVPAAYEVYKADYKEYQESQPVIRSIGVNKAQQKSLWQRVKGWFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDE1</accession>
    <name>A0A0A7HDE1_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CxxC_CXXC_SSSS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209749.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636169"/>
    <dbReference type="KEGG" id="vg:26636169"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013429">
        <property type="entry name" value="Regulatory_FmdB_Zinc_ribbon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09723">
        <property type="entry name" value="Zn-ribbon_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00834">
        <property type="entry name" value="CxxC_CXXC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02605">
        <property type="entry name" value="CxxC_CxxC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxxC_CXXC_SSSS" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="57" mass="6634" checksum="21B883E3B3ED2219" modified="2015-03-04" version="1">MPLYDYKCQSEDCAKEYEKIKKISERDNDVCPDCHRLAVRLVSAPKHVNGGFYDLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDE6</accession>
    <name>A0A0A7HDE6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209754.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636174"/>
    <dbReference type="KEGG" id="vg:26636174"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="85" mass="9498" checksum="298C5F507287044D" modified="2015-03-04" version="1">MITSFKIGQQYEMSAIQAAEAGLTKAFECAFTNIRGKIFTVNKVAVYDKETDMNKGIYLNVSNAKGRREIMVVQPNQLAMFNEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDH5</accession>
    <name>A0A0A7HDH5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209779.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636199"/>
    <dbReference type="KEGG" id="vg:26636199"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="119" mass="13741" checksum="DEC76BCB18FD767C" modified="2015-03-04" version="1">MSYYNFLDFELVSNNDGNARYEFREPRFNQAIGYIIVKDDFIIKARSFMVMDGPYEDTRGYPFDKKNVRDCAIWITGNPEIGVMISTEANDILEGVWAKAQESSIAIDDQIFNAFMKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDJ1</accession>
    <name>A0A0A7HDJ1_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation repressor protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">regA</name>
        <name evidence="3" type="ORF">VR25_052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Controls the translation of a number of proteins (such as regA itself, rIIB and at least 35 others) by binding to their mRNA.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209794.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636214"/>
    <dbReference type="KEGG" id="vg:26636214"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002702">
        <property type="entry name" value="Transl_repress_RegA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036516">
        <property type="entry name" value="Transl_repress_RegA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01818">
        <property type="entry name" value="Translat_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55064">
        <property type="entry name" value="SSF55064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="122" mass="14538" checksum="B95871D0FE697CF5" modified="2015-03-04" version="1">MIEITLKQPEDFLKVKETLTRMGIANNKDRVLYQSCHILQKQGRYYIVHFKEMLRMDGRQVDIDGEDYQRRDSIAQLLEDWGLIAIKEEEHNELFAVTNNFRVISFKQKDDWKLVAKYTIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDJ7</accession>
    <name>A0A0A7HDJ7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209799.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636219"/>
    <dbReference type="KEGG" id="vg:26636219"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035342">
        <property type="entry name" value="Gp45.2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17470">
        <property type="entry name" value="Gp45_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="63" mass="7492" checksum="1DF3E557D032EE81" modified="2015-03-04" version="1">MADFLTGQHLLAVPEIKRYVLVNTFSKDEHLVTERDLQNAFGEEYVKIIANRHKAWFAYEYFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDL9</accession>
    <name>A0A0A7HDL9_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anaerobic ribonucleoside-triphosphate reductase-activating protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Class III anaerobic ribonucleotide reductase small component</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">nrdG</name>
        <name evidence="13" type="ORF">VR25_077</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glycyl-[protein] + reduced [flavodoxin] + S-adenosyl-L-methionine = 5'-deoxyadenosine + glycin-2-yl radical-[protein] + H(+) + L-methionine + semiquinone [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:61976"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:14480"/>
            <dbReference type="Rhea" id="RHEA-COMP:15993"/>
            <dbReference type="Rhea" id="RHEA-COMP:15994"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29947"/>
            <dbReference type="ChEBI" id="CHEBI:32722"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:140311"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the organic radical-activating enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209819.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636239"/>
    <dbReference type="KEGG" id="vg:26636239"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043365">
        <property type="term" value="F:[formate-C-acetyltransferase]-activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012837">
        <property type="entry name" value="NrdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001989">
        <property type="entry name" value="Radical_activat_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352:SF2">
        <property type="entry name" value="PTHR30352:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000368">
        <property type="entry name" value="NrdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00299">
        <property type="entry name" value="anaerobic_ribonucleoside-triph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02491">
        <property type="entry name" value="NrdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01087">
        <property type="entry name" value="RADICAL_ACTIVATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AIZ02421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="156" mass="18132" checksum="E7842A895456C6DF" modified="2015-03-04" version="1">MNYDRIYPCDFINGPGCRTVLFVTGCLHKCEGCYNKSTWNARNGVPFTGETLEQLIECLNNDYIEGLTITGGDPLYPDNRDVIHSVVQTIKNLYPNKSIWLWTGYKFEDIKQLEMIKYVDVIIDGKYEKNLPTKKLWRGSDNQRLWSNTDGVWKHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDM5</accession>
    <name>A0A0A7HDM5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative peptidase inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209824.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636244"/>
    <dbReference type="KEGG" id="vg:26636244"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="57" mass="6649" checksum="9A4769F8DF95C4AD" modified="2015-03-04" version="1">MSTKIEVGRHKGRLIEHSLYELSDSRKLPDEESALIFAAADYIHWLEAQLRFSDEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDN6</accession>
    <name>A0A0A7HDN6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209834.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636254"/>
    <dbReference type="KEGG" id="vg:26636254"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="71" mass="8470" checksum="F39ABD2AD25CDBBB" modified="2015-03-04" version="1">MEIVGFILLYFMLGFMTTIIIHKSGDWNPVEIESSYDAVFITLVWPLLWFVWAIMMVFWPIAKFYEKLFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDQ6</accession>
    <name>A0A0A7HDQ6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209854.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636274"/>
    <dbReference type="KEGG" id="vg:26636274"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="61" mass="7270" checksum="CA7047F40FFAA6F0" modified="2015-03-04" version="1">MITKEQKNKILDMIETVVDAKSEYDEELHTEYYSREDYYKALEALNKASDDLENYLESITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDR6</accession>
    <name>A0A0A7HDR6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_122</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209864.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636284"/>
    <dbReference type="KEGG" id="vg:26636284"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="98" mass="11665" checksum="8BDA0125817F5B0C" modified="2015-03-04" version="1">MTHEELFDQIYFIPKVRSEDFVKNFEIFNKANFFEYVFLSGPFIGSRFRCTAPSIRLMKLVPYFTLEFISGPCKGIITRSLLTYDQDVRLISDWKKYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDS9</accession>
    <name>A0A0A7HDS9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_137</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209879.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636299"/>
    <dbReference type="KEGG" id="vg:26636299"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="109" mass="13173" checksum="B5CD820FC6B7ED7F" modified="2015-03-04" version="1">MHRDSVFKYLLKTDKEFYMDGQAFLFVRGKRETFYKCDLSMHHHMYHTHGESILGFSADETKRIAMYYDHFKLNDCGDNALVWNSSWRRWDTVDNNKLFLEYCRSGIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDT5</accession>
    <name>A0A0A7HDT5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_147</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209889.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636309"/>
    <dbReference type="KEGG" id="vg:26636309"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="101" mass="11910" checksum="862AA662982B8669" modified="2015-03-04" version="1">MKFIINLALVDFDKTGNFASAENMIRNTKFKVQVQQAVAKEFFTDSFTKVVNHLNVVVKFTREAETTVEFDFECRYHDEYVRRILNIVSDELYYGVQENKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDU6</accession>
    <name>A0A0A7HDU6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209899.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636319"/>
    <dbReference type="KEGG" id="vg:26636319"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="110" mass="12115" checksum="EC6E092AD32D61BE" modified="2015-03-04" version="1">MNIKTYNEFLAESAINETKSIDDSEGSLKFGLSKNADGVFFQIGNERFQTSKYSKAAVEAVLKSGGKWKGKEGTKEIGIAVDGGMAYFKIGDEQFIMSARGRKELAKLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDZ6</accession>
    <name>A0A0A7HDZ6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_197</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209939.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636359"/>
    <dbReference type="KEGG" id="vg:26636359"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="287" mass="32848" checksum="3ECE34FB6135C849" modified="2015-03-04" version="1">MEPVKAVLEPDVIDVEYGNTYSATVTLSPIENIPDGSVIRYDWVVNNKFVGTGEATRTTQPSQTGNYVLSCRVFITPPNENTVMITTNKSYGYVYKNSDTSPVDAEILYDNKIYQIGSKVRLLAVANNPDTNFVKGIIWKDADGKIIGIGREYIHTMQSEYDIVRAKVTMDSPIRDEFSKNFTIHLYAINVQEGTCIRYIHPLDHRDAGFIWCGWWVMDEIQRAIKLGLDWKNPKELDLNYKCDLETLALLLKTYPEAEVQESRHGYIITRLQIETGEIYKKPYEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE06</accession>
    <name>A0A0A7HE06_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Baseplate hub subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VR25_207</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209949.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636369"/>
    <dbReference type="KEGG" id="vg:26636369"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098025">
        <property type="term" value="C:virus tail, baseplate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1920.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043085">
        <property type="entry name" value="Gp27_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043083">
        <property type="entry name" value="Gp27_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043084">
        <property type="entry name" value="Gp27_dom4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015180">
        <property type="entry name" value="Phage_T4_Gp27_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015181">
        <property type="entry name" value="Phage_T4_Gp27_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09097">
        <property type="entry name" value="Phage-tail_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09096">
        <property type="entry name" value="Phage-tail_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage-tail_1" evidence="3">
        <location>
            <begin position="7"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Phage-tail_2" evidence="2">
        <location>
            <begin position="206"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AIZ02551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="389" mass="44818" checksum="B9130EACC2B20944" modified="2015-03-04" version="1">MTAKSMQREGFPNISIRLYEDYDAWLEHRFVELAATFTTLTMRDSLYGRNEGLLQFYDTKNLHTKMNGEQIIQVSVKNANSDRTQSRIYGSKHFAVSVDAKGDNIITIQLAPIHEIEDLKFSRMFYPSVQETLVEMTGVIYQDRPLLAPPINGINVYAPNVPWCDSMNQYMEFIREVGLAVESDKFVFVWEDIDGISIQDYEWLTTQEPINFVVGEPRLVGQFVQNLETPLAFDFEWLTKANQHTRKPYENATVYAHSFLDKNATRITFGEGQNSILVSRSGGYSDYTYRNGFEEAQRLITMSQYDGYAHCKTYGNFELTPGDKINFYDPKNQFKYDFYVDEVIHEVSNNTSITNLYMFTNGKPIEVEEPPKVKNELKTDSADEENTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE28</accession>
    <name>A0A0A7HE28_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_212</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209954.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636374"/>
    <dbReference type="KEGG" id="vg:26636374"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035134">
        <property type="entry name" value="DUF5498"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17602">
        <property type="entry name" value="DUF5498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="107" mass="12076" checksum="3A76274587D93459" modified="2015-03-04" version="1">MFISIAHEENKMKSSFRFNGQELVVENVIPASEEFDSAVGNELRRVFGEDKKFDLRPVENFVNSEQTENIFNGIVTGQLESEAPIAITVFVKKEAVMTVAGFISFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE44</accession>
    <name>A0A0A7HE44_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209959.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636379"/>
    <dbReference type="KEGG" id="vg:26636379"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012596">
        <property type="entry name" value="Phage_T4_Y12G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08010">
        <property type="entry name" value="Phage_30_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="SSF143990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="152" mass="17208" checksum="9638C2F2981DEAE8" modified="2015-03-04" version="1">MSELEIRSNFPWPSCALSNFAKWPFVMDGIQFGGLEGFLQGCKVRNHEQQKRIFGMSGLVAQQTGRAYARAADRGTLFWLGIPFSRYSAAWKELYTSAYFEAALQNKGFRDALQATKGKVLKHSMASHLTVHDTILTEQEFIDILNQLRDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE50</accession>
    <name>A0A0A7HE50_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_227</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209969.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636389"/>
    <dbReference type="KEGG" id="vg:26636389"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024401">
        <property type="entry name" value="WYL_prot"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10902">
        <property type="entry name" value="WYL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="99" mass="11458" checksum="E14119997F161B2D" modified="2015-03-04" version="1">MILTEQETIHLREKVKTILSVGFHEVLFEKADGSTRRMTCTRDLDLLPYKEIQAPGPETSKEPVSYIRVFDTKLNEWRSFCFNKLISVNGLQTETLLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE64</accession>
    <name>A0A0A7HE64_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="4 12">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">nrdA</name>
        <name evidence="14" type="ORF">VR25_247</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="12">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4 12"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209989.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636409"/>
    <dbReference type="KEGG" id="vg:26636409"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="PTHR11573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="SSF48168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="13">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AIZ02591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="751" mass="85147" checksum="53EED0D5703C09C7" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE67</accession>
    <name>A0A0A7HE67_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209994.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636414"/>
    <dbReference type="KEGG" id="vg:26636414"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035392">
        <property type="entry name" value="DUF5417"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17438">
        <property type="entry name" value="DUF5417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="79" mass="9057" checksum="9A670F6F0F6C6A1F" modified="2015-03-04" version="1">MKLKRESIKDSEVKGKWYFTIQGNNPEALEKAEETLCAMGWKDECDGCPLYEDGSSSGFWIHHSDVDQFKADWKIAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE92</accession>
    <name>A0A0A7HE92_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_292</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210034.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636454"/>
    <dbReference type="KEGG" id="vg:26636454"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="65" mass="7306" checksum="F823E37D7706DF1B" modified="2015-03-04" version="1">MLGFQARVVEEYDQLVLKINALETFVKGGVFETLDNRQQGLLNAQLDAMSAYAHVLAIRISYFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFQ7</accession>
    <name>A0A0A7HFQ7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_016</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209758.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636178"/>
    <dbReference type="KEGG" id="vg:26636178"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="98" mass="11880" checksum="079B30DAEB9436D9" modified="2015-03-04" version="1">MYYAYVLVHKDKDGFEHPLEYDGKVTLYTTKAGADYELANYSYTTNRYLRMGRIETRYIPRKWWFDKRETKTVFPTEEHARELKLVLDTLYVKRVKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFR7</accession>
    <name>A0A0A7HFR7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_026</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209768.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636188"/>
    <dbReference type="KEGG" id="vg:26636188"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="73" mass="8568" checksum="3307129EE246FBAC" modified="2015-03-04" version="1">MLNRWIKPNKALDEIIAHDVHFKYGLGVFDEVIVHSFMMHDDDSLEFNIEIRCSILKSVVMMVKLNLNEVSYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFT5</accession>
    <name>A0A0A7HFT5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Head vertex assembly chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209788.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636208"/>
    <dbReference type="KEGG" id="vg:26636208"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021049">
        <property type="entry name" value="Phage_T4_Gp40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11113">
        <property type="entry name" value="Phage_head_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="113" mass="12883" checksum="01E25D54ACD4717D" modified="2015-03-04" version="1">MNDIDLSDLDNFEKDAEGAKAPSVPYYEKSLEIIRQSMGTVRQEILLSLPDGSSHIVYVTGIKIEPSGKVSVDFGTPSEDRKAELAVHVEKCVTMQIQDEIDKIKMKKRWWKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFV4</accession>
    <name>A0A0A7HFV4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209803.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636223"/>
    <dbReference type="KEGG" id="vg:26636223"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035136">
        <property type="entry name" value="DUF5486"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17588">
        <property type="entry name" value="DUF5486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="57" mass="6472" checksum="DF5C043C12E7D36F" modified="2015-03-04" version="1">MTSSTDFDKIKSDKNEMMLQFEAARIKAENEGTITYKTIKFKSSHEPLYGVLIGKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFX6</accession>
    <name>A0A0A7HFX6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_086</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209828.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636248"/>
    <dbReference type="KEGG" id="vg:26636248"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="55" mass="6281" checksum="D6C2A63FEC7A72C1" modified="2015-03-04" version="1">MIELMLGVLYIIIGIGYAKTLAKLDDFGAGDFCWWLTSMICWPLFLVGASFWNFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG18</accession>
    <name>A0A0A7HG18_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative internal head protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ip10</name>
        <name evidence="1" type="ORF">VR25_126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209868.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636288"/>
    <dbReference type="KEGG" id="vg:26636288"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="104" mass="11810" checksum="2FB5CB1631E7A84E" modified="2015-03-04" version="1">MKTYQEFITESTQQRVEGGYVWIEQLTPPSETSTGSWKITVDGPGGKRKTIKEIKGYYDEAKSWAGSHVMQIKIANPDNVHAAKAFRRIGNKLYDAFLRDFPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG44</accession>
    <name>A0A0A7HG44_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209893.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636457"/>
    <dbReference type="KEGG" id="vg:26636457"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="159" mass="18454" checksum="778BF2A0F7DE1DD3" modified="2015-03-04" version="1">MNIKFGQTIPKGYVIEIETWENDGDNYKTQTIFGVEEQEIQQYKYILELFQGSHCNYPDKCGNSEWDVVKDLVIAHIESGVKSGQLTSEFINKTLCIENLENLVEGDNDQEFELLYSLQELLGEPVEYDSDFMRVVSWVKLYIIEEEIQIPNVKALDML</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG50</accession>
    <name>A0A0A7HG50_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative internal head protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ip9</name>
        <name evidence="1" type="ORF">VR25_156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209898.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636318"/>
    <dbReference type="KEGG" id="vg:26636318"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="90" mass="10556" checksum="76342EE465E8831F" modified="2015-03-04" version="1">MKTFNELFNESQLNEEVKISKAVKAMIDNINHLYSIDLTDHITIGNKRNFFAFDISELDQNQINNIERFANDKGLRHETAGYKKYAIYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG55</accession>
    <name>A0A0A7HG55_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tail completion and sheath stabilizer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209903.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636323"/>
    <dbReference type="KEGG" id="vg:26636323"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010667">
        <property type="entry name" value="Phage_T4_Gp19"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06841">
        <property type="entry name" value="Phage_T4_gp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="199" mass="22433" checksum="C08C283C5BF52B2A" modified="2015-03-04" version="1">MSGLYNQTNTTNFILEVSDSNLTQTFKLNVQDVTLPGVHIPVTDVPGGTQGINRSSLPGSTIEFDPLIVNFLCDKDLRAWLDIYKWMLSLNNYITHESKAWHPKGRPEAVTLHILDNNKDKIVMSIHYYGAWPSDLSEIQYSYKEDSDPAINATATFNFKSFAVEIDGIIIEGRPQIDSNAAMQQEIRSKSMHPSMRNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG87</accession>
    <name>A0A0A7HG87_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prohead core protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209928.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636348"/>
    <dbReference type="KEGG" id="vg:26636348"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016415">
        <property type="entry name" value="Phage_T4_Gp68"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004377">
        <property type="entry name" value="Phage_prohead_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="142" mass="16085" checksum="1388C388F25B2AFB" modified="2015-03-04" version="1">MFIIPDDYELTLENIESVSEEAQGQFDSLSEALEKDDINIIVENMFAAGEYEKATVIGALNEGVQLNEFIVKHVSSRGELTRTKDRATRKRNAFQTTGLSKAKRRQIARLATKTKRANPSTQIRAERKRKKARAKRKAFGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG92</accession>
    <name>A0A0A7HG92_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Capsid vertex protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">gp24</fullName>
        </alternativeName>
        <component>
            <recommendedName>
                <fullName evidence="1">Mature capsid vertex protein</fullName>
            </recommendedName>
            <alternativeName>
                <fullName evidence="1">gp24*</fullName>
            </alternativeName>
        </component>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VR25_191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Capsid protein that self-associates to form pentons, building the capsid in association with hexamers of the major capsid protein and one dodecamer of the portal protein.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homopentamer. Interacts with the portal protein. Interacts with the major capsid protein that forms hexamers.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Capsid vertex protein</molecule>
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Part of the icosahedric capsid shell of the immature virion.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Mature capsid vertex protein</molecule>
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Part of the icosahedric capsid shell of the mature virion.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">A proteolytic cleavage gives rise to the mature capsid vertex protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tevenvirinae capsid vertex protein family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209933.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636353"/>
    <dbReference type="KEGG" id="vg:26636353"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019028">
        <property type="term" value="C:viral capsid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04113">
        <property type="entry name" value="CAPSID_P_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038999">
        <property type="entry name" value="CAPSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010762">
        <property type="entry name" value="Gp23/Gp24_T4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07068">
        <property type="entry name" value="Gp23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="1" id="KW-0426">Late protein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_5023452379" description="Capsid vertex protein" evidence="1">
        <location>
            <begin position="1"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023452380" description="Mature capsid vertex protein" evidence="1">
        <location>
            <begin position="11"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage" evidence="1">
        <location>
            <begin position="10"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="426" mass="46632" checksum="4DABB34E7ECBDB21" modified="2015-03-04" version="1">MAKINELLRESTTTTSNSLGRPNLVALTRATTKLIYRDIIAEQRTNQPVAALYGVKYLTPDNEFSFQTGATYGGEVGSKDRTTIPELATATQPVAKGEYVKYQNIVYKALVDNPFATTTETVLSDVLQEGLIASTIRLVPDAAHTEKFEAGDVEISNAVFQVNKWNAPVKSRKLKTALTVELAQDMEANGFNAPAFLEDLLATTMADEINKDVLQSLITVSKRYKVTGVSDKGFIDLTYDSAPEGARKLYELVCEMNSEIQKTTSYSGTFVVASSRVAAMLAGSGWLKHKPEDEQWLPETAYGYLINGLPVFCDVNSPLDYVTVGVKENYGGNEVVGSIFYAPYTEGLDLDDEEHVGAFKVIVDPDSLQPSISLMVRYALSANPYTVAKDDKEARIIDATNMDLMAGQSNMSYLLGVKLPPIIYEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGC5</accession>
    <name>A0A0A7HGC5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dda</name>
        <name evidence="2" type="ORF">VR25_015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209757.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636177"/>
    <dbReference type="KEGG" id="vg:26636177"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041214">
        <property type="entry name" value="SH3_14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18343">
        <property type="entry name" value="SH3_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="26"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="442" mass="50695" checksum="1D82216440AEE7E7" modified="2015-03-04" version="1">MIKFEDLNKGQKEAFDYITEAIQRRSGECITLNGPAGTGKTTLTKFVIDHLVRNGVLGIVLAAPTHQAKKVLSKLSGQTANTIHSILKINPTTYEDQNIFEQREMPDMSKCNVLICDEASMYDGPLFKIICNSVPEWCTILGIGDMHQLQPVDPGSTQQKISPFFTHPKFKQIHLTEVMRSNAPIIEVATEIRNGGWFRDCMYEGHGVQGFTSQTALKDFMVNYFSHVKDADMLMENRMYAYTNKSVEKLNNIIRRKLYETDKAFLPYEVLVMQEPHMKELEFEGKKFSETIFNNGQLVRIKDCKYTSTILRCKGESHQLVINYWDLEVESIDEDEEYQVDRIKVLPEDQQPKFQAYLAKVADTYKQMKAAGKRPEWKDFWKARRTFLKVRALPVSTIHKAQGVSVNKAFIYTPCIHMAEASLASQLAYVGITRARYDAYYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGC9</accession>
    <name>A0A0A7HGC9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Baseplate subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209953.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636373"/>
    <dbReference type="KEGG" id="vg:26636373"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="319" mass="34657" checksum="9F9F7D819976BFF4" modified="2015-03-04" version="1">MFTLQEFQTQAINIDLQRNNLFSVVFATAPSSKSQNLLDQFGGALFSNLPVNSDWFGLTQGDLTQGITTLVTAGTQKLIRKSGISKYLIGAMSNRVVQSLLGEFEVGTYLLDFFNMAYPTAGLLVHSVKLPDNTLNYEMDLNHNAPNIKITGREYSPLVLSFRMDSEAGNFRAFNDWVNSVQDPVTQLRALPEDVEADIQVNLHSRNGLPHTVVMLTGCVPVSVSAPELSYEGDNQIATFDVTFAYRVMSTGAVGRNAALEWLEDKVIKGVSGISSDNNLNAEVAKLSRLSGAQSGLTSLYNTFTGSGRAVSGGSQRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGF1</accession>
    <name>A0A0A7HGF1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209973.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636393"/>
    <dbReference type="KEGG" id="vg:26636393"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="77" mass="8722" checksum="248A2110D40A0A3D" modified="2015-03-04" version="1">MLSETPITVEEFHEKVKAFAQAMINHVSQRFPDATLKVIQESARSFMIVINPKDGDQFTQLKLGSDGLVEAQRVYIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGF8</accession>
    <name>A0A0A7HGF8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VR25_241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209983.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636403"/>
    <dbReference type="KEGG" id="vg:26636403"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="117" mass="13137" checksum="3CE83B0FB8E2EF99" modified="2015-03-04" version="1">MQISNITAGLMLALVVTAGSGFYLKAKVDNLKTEVAAVTKVAEDNAKNLQSIKDQVNQINLLDQERQEYVELLQKENDKLRADAKRTKVVAAKPKLVEKQINQSFDKFAQDFQELTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGG1</accession>
    <name>A0A0A7HGG1_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="12">2.7.7.7</ecNumber>
            <ecNumber evidence="12">3.1.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">VR25_050</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="12">Replicates the viral genomic DNA. This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction for proofreading purpose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12 13">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Part of the replicase complex that includes the DNA polymerase, the polymerase clamp, the clamp loader complex, the single-stranded DNA binding protein, and the primase/helicase. Interacts with the polymerase clamp; this interaction constitutes the polymerase holoenzyme.</text>
    </comment>
    <comment type="domain">
        <text evidence="12">The N-terminus contains the 3'-5' exonuclease activity. The C-terminus contains the polymerase activity and is involved in binding to the polymerase clamp protein. A beta hairpin structure is necessary for the proofreading function of the polymerase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12 13">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="12"/>
    <dbReference type="EC" id="3.1.11.-" evidence="12"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209792.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636212"/>
    <dbReference type="KEGG" id="vg:26636212"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039686">
        <property type="term" value="P:bidirectional double-stranded viral DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04100">
        <property type="entry name" value="DPOL_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034749">
        <property type="entry name" value="DPOL_T4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 12 13" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="7 12" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3 12 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 12" id="KW-1194">Viral DNA replication</keyword>
    <feature type="domain" description="DNA_pol_B_exo1" evidence="15">
        <location>
            <begin position="96"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol_B" evidence="14">
        <location>
            <begin position="369"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Polymerase" evidence="12">
        <location>
            <begin position="381"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="12">
        <location>
            <begin position="415"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Binding of DNA in B-conformation" evidence="12">
        <location>
            <begin position="706"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with the polymerase clamp" evidence="12">
        <location>
            <begin position="898"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic; for 3'-5' exonuclease activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic; for 3'-5' exonuclease activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic; for 3'-5' exonuclease activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
            <note>catalytic; for polymerase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="483"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="560"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="623"/>
        </location>
    </feature>
    <feature type="site" description="Optimization of metal coordination by the polymerase active site" evidence="12">
        <location>
            <position position="621"/>
        </location>
    </feature>
    <feature type="site" description="Optimization of metal coordination by the polymerase active site" evidence="12">
        <location>
            <position position="707"/>
        </location>
    </feature>
    <feature type="site" description="Essential for viral replication" evidence="12">
        <location>
            <position position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="AIZ02394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="904" mass="103716" checksum="1231F65A374D4AC9" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGG4</accession>
    <name>A0A0A7HGG4_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sliding clamp</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">DNA polymerase accessory protein Gp45</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">DNA polymerase clamp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VR25_055</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Sliding clamp that encircles the genomic DNA and links the DNA polymerase to the template to control the processivity of DNA synthesis. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. Interaction with the sliding-clamp-loader opens the sliding clamp so that it can be loaded around the DNA template. During transcription, encircles the DNA and tethers host RNA polymerase (RNAP) to it.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotrimer. Interacts with the viral DNA polymerase; this interaction constitutes the polymerase holoenzyme. Interacts with the sliding-clamp-loader; this interaction allows the sliding-clamp-loader to open the sliding clamp. Interacts with the viral DNA ligase. Part of the replicase complex that includes the DNA polymerase, the polymerase clamp, the clamp loader complex, the single-stranded DNA binding protein, the primase, the helicase and the helicase assembly factor. Interacts with the viral RNA polymerase (RNAP). Part of the transcription activation complex containing host RNAP, the viral RNA polymerase sigma-like factor, the late transcription coactivator, and the sliding clamp.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tevenvirinae sliding clamp family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209797.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636217"/>
    <dbReference type="KEGG" id="vg:26636217"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039693">
        <property type="term" value="P:viral DNA genome replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04161">
        <property type="entry name" value="Sliding_clamp_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004190">
        <property type="entry name" value="DNA_pol_proc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015200">
        <property type="entry name" value="Sliding_clamp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046389">
        <property type="entry name" value="Sliding_clamp_T4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02916">
        <property type="entry name" value="DNA_PPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09116">
        <property type="entry name" value="gp45-slide_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1194">Viral DNA replication</keyword>
    <keyword evidence="1" id="KW-1195">Viral transcription</keyword>
    <feature type="domain" description="DNA_PPF" evidence="2">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="gp45-slide_C" evidence="3">
        <location>
            <begin position="116"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AIZ02399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="231" mass="25520" checksum="F30F339F7B352644" modified="2015-03-04" version="1">MKFSKDTIAVLKNFTSIYSGIMLKPGNTILTRSVTGASYGESEINDTIDFEAAIYDLNGFLSILGLVTDQAEVSLAEDASNIIIKDQRSTIHWPAADPSTIVFPAKKIPFPVAKVIFDLKGSDLQQLLRVAGGLSLDTFAITNKDGKIVIHGYNQLEDKELARPLYSLVCGDYEGDAAFKFIINKLNMKMIPADYRVMLWAKDDKFATKFEGTQASYVIAMEQGSSHEFQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGH4</accession>
    <name>A0A0A7HGH4_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA polymerase sigma-like factor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Promoter specificity factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in the transcription of the viral late genes by acting as a late promoter recognition subunit. Associates with host RNA polymerase (RNAP) core and thus replaces the host sigma-70/rpoD subunit in the complex. May also play a role in DNA packaging by interacting with the terminase subunit gp17.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with the host RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ to form the RNAP-gp55 holoenzyme. Part of the transcription activation complex containing host RNAP, the viral RNA polymerase sigma-like factor, the late transcription coactivator, and the sliding clamp. Interacts with the terminase large subunit; this interaction may load the terminase onto DNA for packaging.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tevenvirinae RNA polymerase sigma-like factor family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209807.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636227"/>
    <dbReference type="KEGG" id="vg:26636227"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04164">
        <property type="entry name" value="T4_Sigma_like_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046386">
        <property type="entry name" value="T4_Sigma_like_factor"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-1195">Viral transcription</keyword>
    <feature type="DNA-binding region" evidence="1">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with host RNAP core and recognition of the promoter specific element" evidence="1">
        <location>
            <begin position="14"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with host RNAP" evidence="1">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with host RNAP" evidence="1">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with host RNAP" evidence="1">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="185" mass="21320" checksum="C2809F28E8B9FCAB" modified="2015-03-04" version="1">MNEIKLTKNNYVNNKELLKAISEWKQKLNANTDPNKIIRQNDVIGLAIMLIAEGLSKRFNFSGYTQSWKQEMIADGIEAAIKGLHNFDETKYDNPHAYITMACFNAFVQRIKKERKEMAKKYSYFVHNVYDSRDDDMVALADETFIQDIYDKMTQYESSLVKAPGSDKSAKDKEGDLDFLYGTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGH8</accession>
    <name>A0A0A7HGH8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209812.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636232"/>
    <dbReference type="KEGG" id="vg:26636232"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035141">
        <property type="entry name" value="DUF5484"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17583">
        <property type="entry name" value="DUF5484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="43" mass="5179" checksum="9541EB24D9316DEC" modified="2015-03-04" version="1">MNIKRMFFKQGLYTLNVTPKGDTTKWSVNDWIKFIDENGNWKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGI8</accession>
    <name>A0A0A7HGI8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210023.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636443"/>
    <dbReference type="KEGG" id="vg:26636443"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050792">
        <property type="term" value="P:regulation of viral process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012585">
        <property type="entry name" value="Stp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08133">
        <property type="entry name" value="Nuclease_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="26" mass="3174" checksum="89F1671E6B1D9FD3" modified="2015-03-04" version="1">MSNFHNEHVMQWHRHNLKLTGVFGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGJ0</accession>
    <name>A0A0A7HGJ0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209822.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636242"/>
    <dbReference type="KEGG" id="vg:26636242"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="58" mass="6865" checksum="C8B9CAECFBABBC96" modified="2015-03-04" version="1">MKTVLVYTEKLNGGKVWKLLIKGSPTDRFMATCVGLYTRPTKKMIRQFKRLHRSFYNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGJ2</accession>
    <name>A0A0A7HGJ2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_286</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210028.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636448"/>
    <dbReference type="KEGG" id="vg:26636448"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="38" mass="4712" checksum="9CC087C05F1F4858" modified="2015-03-04" version="1">MKKLLKAIWNMFVLFVVLSIFPIVFMIDHVHVYFNYFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGK6</accession>
    <name>A0A0A7HGK6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209837.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636257"/>
    <dbReference type="KEGG" id="vg:26636257"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="100" mass="11662" checksum="1902E8AD9093CA05" modified="2015-03-04" version="1">MKKYEIDMIDACLKSADHFKLKMHKLRGMVKTPEEKKRYALKEKCKALIMMDKLQMVAAEAHRTRKAEALGVYMAEQIHRAQQAVKSAWFSGENTERTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGL4</accession>
    <name>A0A0A7HGL4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209847.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636267"/>
    <dbReference type="KEGG" id="vg:26636267"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="60" mass="6850" checksum="20368BB350697609" modified="2015-03-04" version="1">MITLEQIEKIIKLARDIEIDSYELAVEHCEGYSYSGIEQCKRDLNSSKANLVEYLNGLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGP0</accession>
    <name>A0A0A7HGP0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209877.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636297"/>
    <dbReference type="KEGG" id="vg:26636297"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="78" mass="9167" checksum="3606B53B3918BEBE" modified="2015-03-04" version="1">MIYYESIGTEVVAKTITREKFKKIFDIAYKKSDYNVRFEDAFCTICPYNEDINGVIAPIVCNSHEALWDEYDSARWDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGQ2</accession>
    <name>A0A0A7HGQ2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209887.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636307"/>
    <dbReference type="KEGG" id="vg:26636307"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="184" mass="20956" checksum="285410A482185D88" modified="2015-03-04" version="1">MSLYTDLISNVDWFGGSGLATETNTVLYRIRGDLGYSNDFLRRTTSRGDTTKLPFIFALAEDLSFADALEIIDVNLGIQRVEFAGLRYSVYALNESDDCVLLNIADDDYHLVCYVALENGDVFGMVDRRPSYSDIKNYDKDELTILADEYTLESRKQQRKLNRFIKECREYAKGVQNANVISAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGS1</accession>
    <name>A0A0A7HGS1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Baseplate wedge subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209907.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636327"/>
    <dbReference type="KEGG" id="vg:26636327"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022607">
        <property type="entry name" value="Phage_T4_Gp53_baseplate_wedge"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11246">
        <property type="entry name" value="Phage_gp53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="200" mass="23576" checksum="040EADEF4E96E585" modified="2015-03-04" version="1">MLFSFFNPIDYDAKTIRKNPASLTKEDVLSIPMTDIFRNYRAYFDKVAVNYTPKTYYIAGAPRPEELSYQLYGNTQLYWVLLMLNDIYDPYYGWLCTQEASYQASIQKYSNVGGNQVLYHVNEDGEKFWNLVSYPDNPYTWYDKGDKNKLYPQYEGPLAAVDIYEDAIRKNEYKREIKIIDPEDIESFISALIREMEKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGS7</accession>
    <name>A0A0A7HGS7_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Baseplate wedge protein gp7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VR25_170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Baseplate protein. Involved in the tail assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds to gp10 homotrimer; disulfide-linked. Heteromultimer with gp10; a gp10 molecule is disulfide-linked to gp7 and the other two remaining gp10 molecules form a disulfide bond.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Present in the baseplate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the T4likevirus baseplate wedge protein gp7 family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209912.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636332"/>
    <dbReference type="KEGG" id="vg:26636332"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098025">
        <property type="term" value="C:virus tail, baseplate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098003">
        <property type="term" value="P:viral tail assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04103">
        <property type="entry name" value="BP07_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034697">
        <property type="entry name" value="GP7_T4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0426">Late protein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-1226">Viral baseplate protein</keyword>
    <keyword evidence="1" id="KW-1188">Viral release from host cell</keyword>
    <keyword evidence="1" id="KW-1245">Viral tail assembly</keyword>
    <keyword evidence="1" id="KW-1227">Viral tail protein</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="881"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Interchain (with GP10)" evidence="1">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="1031" mass="119917" checksum="B317A15F5AF99E1D" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGV3</accession>
    <name>A0A0A7HGV3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209937.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636357"/>
    <dbReference type="KEGG" id="vg:26636357"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021404">
        <property type="entry name" value="Phage_T4_Gp24.3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11242">
        <property type="entry name" value="DUF2774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="63" mass="7423" checksum="0D04AA6AFAFCBF4F" modified="2015-03-04" version="1">MNKVKVHFLHETGMTFIEIAKVLGGTAKEMAKAWVDVEQAKEKFKSREKIVYRKRLFNKKVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGV7</accession>
    <name>A0A0A7HGV7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">uvsW</name>
        <name evidence="2" type="ORF">VR25_200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209942.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636362"/>
    <dbReference type="KEGG" id="vg:26636362"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="122"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="499" mass="57703" checksum="F226D239F32E2D5E" modified="2015-03-04" version="1">MDIKINFLNFSHVHVECEDSIFYELRDYFSFEAENYRFNPKFRAGVWDGRIRLLDYNRKLPYGLVNQIKKFADQFGYSFWIDPQITEKEEISRVDFDKWVESKEIYSGHTKITPHWYQTDAVYDGLVNRRKILNLPTSAGKSLIQALLARYYLENYEGKVLILVPTTALVDQMINDFVDYRLFPREACLGIRSGTKRDSDAMIYVSTYQTAVKQPKEWFSQFGQFMNDECHMATGKSISTVIEGLTNCMFKFGLSGSLRDGKANLMQYMGLFGDIFKPVSTSQLMDEGQVTDLKINSIFLRYPDEFTIKMKGKSYQDEIKVITKATRRNKWVTNLALKLAKKDENVFLMFKNIEHGKSMFEMLKEAGHENVYYVSGEVDTETRNALKVMAENGKGIIVVASYGVFSTGISVKNLHHIIFAHPVKSKVIVLQTIGRVLRKHESKSTANVWDIVDDMGVKPKSANAKKKYVHLNFALKHALERIQRYADEKFNYIIKQVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGZ3</accession>
    <name>A0A0A7HGZ3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209962.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636382"/>
    <dbReference type="KEGG" id="vg:26636382"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="64" mass="7052" checksum="B860C36FAECD26DF" modified="2015-03-04" version="1">MQLFLSQTVQLKGVGIPGMISKVLPAFKFGGIVIKEAYLVLWVDGTEDVRMDGELSVIKCLRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGZ7</accession>
    <name>A0A0A7HGZ7_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lysis inhibition accessory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rIII</name>
        <name evidence="2" type="ORF">VR25_225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Probably binds to the cytoplasmic part of the holin during lysis inhibition and stabilizes the holin-antiholin complex thereby resulting in a robust block of the hole formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homooligomer. Interacts with holin (via N-terminus).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the T4likevirus lysis inhibition accessory protein rIII family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209967.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636387"/>
    <dbReference type="KEGG" id="vg:26636387"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901218">
        <property type="term" value="P:negative regulation of holin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04112">
        <property type="entry name" value="Linr3_BPT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034688">
        <property type="entry name" value="Linr3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="site" description="Interaction with holin" evidence="1">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="84" mass="9539" checksum="6200EF8FEDA238EF" modified="2015-03-04" version="1">MSLNKQLQHALELQRTAWNNGHENYGASIDVEAEALEILQYFKHLNPVQTDLRAVLEAKDELKFAKPLASAARKAVRHFVVTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HH01</accession>
    <name>A0A0A7HH01_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209977.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636397"/>
    <dbReference type="KEGG" id="vg:26636397"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="66" mass="7812" checksum="8B457AF0DDC7A5AC" modified="2015-03-04" version="1">MNNIEKIFRKIEEIEKGYEYFFSVWPLTDGRIGLDVMDYKDEDKVDGGIFTSATALLDFLEEHYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HH04</accession>
    <name>A0A0A7HH04_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209982.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636402"/>
    <dbReference type="KEGG" id="vg:26636402"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="97" mass="11517" checksum="6460791427DB8661" modified="2015-03-04" version="1">MMKSIMAVCLAIGLVSCAQKPVVEPTIQVHPNWPQTLMEYRQQWEVKVIDGQPWVGMPFEASQEFRIWMNDVKRYVHDQKGMLCYYRSELKEERCHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HH06</accession>
    <name>A0A0A7HH06_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endonuclease II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">denA</name>
        <name evidence="4" type="ORF">VR25_245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209987.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636407"/>
    <dbReference type="KEGG" id="vg:26636407"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10436">
        <property type="entry name" value="GIY-YIG_EndoII_Hpy188I_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044556">
        <property type="entry name" value="EndoII-like_GIY-YIG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016413">
        <property type="entry name" value="Phage_T4_DenA_endoDNaseII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004362">
        <property type="entry name" value="Endonuclease_II_phage_DenA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="3">
        <location>
            <begin position="31"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AIZ02589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="136" mass="15849" checksum="FB7BBC1DEDEF94FA" modified="2015-03-04" version="1">MKQIADEYSFIKYAELELVDGKIPTLTLANKKNVIYAISVDDELVYIGKTNNLKKRINYYRTAINRIEQTSDSNKSRMIHEALQAGKKVVFYARQCFNLSMTNELGTMSVETMSLEEPMFIKLFNPPWNYQHKVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HH10</accession>
    <name>A0A0A7HH10_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209992.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636412"/>
    <dbReference type="KEGG" id="vg:26636412"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="75" mass="8779" checksum="DE87EB43FCFA907E" modified="2015-03-04" version="1">MIVVFEYHDSDSWTLFTALNDPDVNEFEKAFNDAADMSVNNYELFKAAVTLFKDGVKIDEDIFYETNEAIAWWEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HH11</accession>
    <name>A0A0A7HH11_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209997.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636417"/>
    <dbReference type="KEGG" id="vg:26636417"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004885">
        <property type="entry name" value="FRD2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03197">
        <property type="entry name" value="FRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="121" mass="13625" checksum="4910CEF9670C1B5F" modified="2015-03-04" version="1">METGKFYVLDPAAKKQFIAGSPDDNSRMVKLMGQHGSSFKVLDMCFIDGDYFVEKVEMKDGTILDSMDDADEYFELAEWEFRHFLEVDGDAPVVDTQTIHVQVNHKNAAEVIALIKATFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HH16</accession>
    <name>A0A0A7HH16_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Double-stranded DNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dsbA</name>
        <name evidence="1" type="ORF">VR25_260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210002.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636422"/>
    <dbReference type="KEGG" id="vg:26636422"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020313">
        <property type="entry name" value="Double-stranded_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11126">
        <property type="entry name" value="Phage_DsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="89" mass="10158" checksum="5F192A7C793439FC" modified="2015-03-04" version="1">MKEKKVKVEFCPDTHGAELAKLIKAASDTKLKMEAYADEIKDLKDKAKTELGVDGKMFNTQLGLYHKGTRERFEDEKTEAVELYDVLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HH31</accession>
    <name>A0A0A7HH31_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210027.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636447"/>
    <dbReference type="KEGG" id="vg:26636447"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="68" mass="7906" checksum="49C9B01A96CD255D" modified="2015-03-04" version="1">MNYQSQFKKSNRRFDFMFKFIVAMIILIFIGAIVMIGFQVWIAAEVFTQIQDNGLKSVVDVIWNGAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HC96</accession>
    <name>A0A0A7HC96_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative mRNA metabolism modulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">goF</name>
        <name evidence="2" type="ORF">VR25_008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209750.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636170"/>
    <dbReference type="KEGG" id="vg:26636170"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="126" mass="14507" checksum="7C1BAAC820B91C21" modified="2015-03-04" version="1">MSKFETDKWYYFKDNVSESRFRLLCTDNDNIADAIINGEGFRPVKIEGGDVYKIELSTGGMESLFITEEEFHFFEEEKDDGDEDGVPDAEETEAPEITAFPLTKITISNNEEAWSVFQMLKAHFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCC1</accession>
    <name>A0A0A7HCC1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209780.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636200"/>
    <dbReference type="KEGG" id="vg:26636200"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="145" mass="17025" checksum="95CAFB6E010AC755" modified="2015-03-04" version="1">MINRNLVIKKLRCKNPNAQAYRVFWSDEIQYLGYFLVDSDDRIVFAHKLLNKELNQWKDFPKMVTKPLTRNTMIELTHLFSGGVPHKVTFEGFEFNNINHNSELVDDVINASIPSKYIKNSLLKILENPVYSVDDQIFNAFMKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCD0</accession>
    <name>A0A0A7HCD0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209790.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636210"/>
    <dbReference type="KEGG" id="vg:26636210"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="167" mass="18496" checksum="0EC98743E733ACCD" modified="2015-03-04" version="1">MKKLAIAAVLLLSGCAYQGDVVRADEVGQARVAADKARYNGSFDFKGGTGLIYKRANSQCGNNCANYAQREVEYQREQAAKHDEVIAKLEAETKRQNDLDMVARIAETCAAYIGMQINVMRAEAYRAMETGAPEAKEYNALYQRSAKARLTYINKCIAKEKARQGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCE0</accession>
    <name>A0A0A7HCE0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VR25_058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209800.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636220"/>
    <dbReference type="KEGG" id="vg:26636220"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="2">
        <location>
            <begin position="8"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="368"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="560" mass="63531" checksum="C6B3374827F3A45D" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCF1</accession>
    <name>A0A0A7HCF1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_068</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209810.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636230"/>
    <dbReference type="KEGG" id="vg:26636230"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016409">
        <property type="entry name" value="Phage_T4_Gp55.2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004270">
        <property type="entry name" value="UCP004270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="108" mass="12087" checksum="024F3E6E05124506" modified="2015-03-04" version="1">MTASITNTIANFAFAKVNTLMKSGFVTPEILDQWEGDVQKLIIAEGQTMGKARIRESLVQYILNEFDVVAFGLPLPRENKEVSDKAIKRMNSQRKKGFVDLKIVKGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCF8</accession>
    <name>A0A0A7HCF8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_073</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209815.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636235"/>
    <dbReference type="KEGG" id="vg:26636235"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="60" mass="7002" checksum="4E4612CEE8F81FE5" modified="2015-03-04" version="1">MVVQDKEIKVDRYYSVNGYPVQVTKVTDQDVWYRPLKWPDAPLMVCDRSLFNTVAKGPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCH5</accession>
    <name>A0A0A7HCH5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_014</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209756.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636176"/>
    <dbReference type="KEGG" id="vg:26636176"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="79" mass="9258" checksum="97D8ACFBE174EDA9" modified="2015-03-04" version="1">MYKVYKEDLDNLIYGIHDAVEFYEDNPTIVQQGNYVLLELSLIQKRMAAIEYFNNEEPGIFISDYVAGEIQKLKEMCDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCH8</accession>
    <name>A0A0A7HCH8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209835.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636255"/>
    <dbReference type="KEGG" id="vg:26636255"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="228"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="282" mass="32414" checksum="759A7E3E6F2CCA83" modified="2015-03-04" version="1">MSQAINEIRSEVKKVVKFNSIPSTKDVVLNVLYMMWNKFNVCTNSAEFTKIFNKTTGLLTLEDRVMKSLQRSGMLSRANAKILLKNYNKGYDLYGRAISTMTFDEVVKDLHTNQRRLLALGARLASGQDKQMTFKTNNSLDYKLFNVIKGQNEGEYSISSFSGCQYENWKFHLRLALSELEHHGVLTFYDVKTGGVQRIKLCQIKDRVVVESPSEQAPKMEPVPVRSNEKYSEQIELFTKQIEELNITIQQQDDEIFRLSGLNNAAKAERHKLMNVIKLLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCJ3</accession>
    <name>A0A0A7HCJ3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209776.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636196"/>
    <dbReference type="KEGG" id="vg:26636196"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010762">
        <property type="entry name" value="Gp23/Gp24_T4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07068">
        <property type="entry name" value="Gp23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="55" mass="5821" checksum="9769D14BA9DDA716" modified="2015-03-04" version="1">MKTFKDFINEDMVAGDAGGNPTNIATGTTSGAVVNKGPEQIPSKKRKNKDDKPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCJ7</accession>
    <name>A0A0A7HCJ7_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein spackle</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sp</name>
        <name evidence="2" type="ORF">VR25_039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Inhibits viral DNA ejection into the host cytoplasm, thereby confering the infected host bacteria with immunity against secondary phage infection. Achieves superinfection exclusion by localizing to the periplasm and inhibiting the activity of tail-associated lysozyme, thereby preventing penetration by the tail tube of incoming phages.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Interacts with the baseplate central spike protein; this interaction selectively inhibits the lysozyme activity of the baseplate central spike protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tevenvirinae spackle protein family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209781.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636201"/>
    <dbReference type="KEGG" id="vg:26636201"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04159">
        <property type="entry name" value="SPACKLE_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046391">
        <property type="entry name" value="SPACKLE_T4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-1049">Host periplasm</keyword>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1260">Superinfection exclusion</keyword>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="29"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="97" mass="10813" checksum="58F3B8A7ABFA93AB" modified="2015-03-04" version="1">MKKLSIAAILVLASCHAAPVTAGYDKDLCEWSMTADQEAVEHQIYADIMNITKRDQPNKVKEVSDQLASGGVMQYNYVLYCDPNFENENIVKEVTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCK5</accession>
    <name>A0A0A7HCK5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Immunity to superinfection membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">imm</name>
        <name evidence="2" type="ORF">VR25_049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209791.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636211"/>
    <dbReference type="KEGG" id="vg:26636211"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016410">
        <property type="entry name" value="Phage_imm"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14373">
        <property type="entry name" value="Imm_superinfect"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004305">
        <property type="entry name" value="Phage-assoc_immunity"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="78" mass="8673" checksum="8B392547CB3A2D86" modified="2015-03-04" version="1">MEALIVGAGVFGFGSLVVMFIGYFLPWIIALLRGTRSNVGIFFINLLFGWTMIGWVIALIWAIVAERKTNAQIIVVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCK9</accession>
    <name>A0A0A7HCK9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative internal head protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ip5</name>
        <name evidence="1" type="ORF">VR25_128</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209870.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636290"/>
    <dbReference type="KEGG" id="vg:26636290"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="93" mass="10390" checksum="3033F2FCCAA4C863" modified="2015-03-04" version="1">MKTYNEFLTVTTLNEATDAFATKLGTALVEAESLLARISELASKVDTRKFERTSDITKLEALLRMCDKPEEIAKNGSLMKQRLEKYISAASTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCL4</accession>
    <name>A0A0A7HCL4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_133</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209875.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636295"/>
    <dbReference type="KEGG" id="vg:26636295"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="229" mass="26452" checksum="D546DFEE5CDBB4D5" modified="2015-03-04" version="1">MNSSKTFNSKMREVGQFAQDISNDQIKNEPMFFNCDAYFAHKHGGPITRSFIENLPEDWQCGPDIVFDSRVHMLMPGWYPAIPGFHHDDVPRPDIPAGQHFITAGQPDYDNPRYHSEHILGLVNASVCPTNFALGTSEFSQIPDGELIYRRWHQEVLEKIKAGELLVQEAPDRTLCEFNWQTWHTGTKTVGNGWRWFGRVSRNTDRVKKITNEIRVNAQVYLEFPMEGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCL6</accession>
    <name>A0A0A7HCL6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_064</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209806.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636226"/>
    <dbReference type="KEGG" id="vg:26636226"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020248">
        <property type="entry name" value="Y03I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17595">
        <property type="entry name" value="DUF5491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="77" mass="9213" checksum="03CDFB1AAA61085A" modified="2015-03-04" version="1">MEHQFDITDFLDKIEEDFTALPYFIKLYLRDIKGLPIDIDPLNVRNLEFTSPDNNVDYRYHVDNANLYFTIELTPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCL7</accession>
    <name>A0A0A7HCL7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209880.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636300"/>
    <dbReference type="KEGG" id="vg:26636300"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="74" mass="8307" checksum="AD76BC4B35B39097" modified="2015-03-04" version="1">MSDINELEKAALELAALYKKVKDMASAQDFGIELDDYDGEVRLEDWLNSSCYGEEAGRTFVAHPDGKIWYPSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCM0</accession>
    <name>A0A0A7HCM0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209885.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636305"/>
    <dbReference type="KEGG" id="vg:26636305"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="117" mass="12945" checksum="850334C2F3C92E41" modified="2015-03-04" version="1">MERPSLASHVYQLAEYDIGANLLLGIATAMLGGLVGLVMTTVMAAIEGVMPIEMGFFMIIAPAVVAYFIPVVYDICYTNALNAPIRKRYALAMAEYNKFLNKTKRNDLETFIKECKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCM4</accession>
    <name>A0A0A7HCM4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nrdH</name>
        <name evidence="1" type="ORF">VR25_074</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209816.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636236"/>
    <dbReference type="KEGG" id="vg:26636236"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="105" mass="11829" checksum="F7AFCB73F33966FB" modified="2015-03-04" version="1">MGQNSTKIEIYGIPEEVGRCPGCMHIRSLLGSLNLPYTFYSVLNKQGSEIAYDRPLIVSLAKRAGYPTLNIRYPVIFVNDEKMTNIPAFKTKLISLGYDQDLIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCM5</accession>
    <name>A0A0A7HCM5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209890.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636310"/>
    <dbReference type="KEGG" id="vg:26636310"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="147" mass="16233" checksum="E168A171C248764A" modified="2015-03-04" version="1">MKTSKLVKYVKLALNNSSEAEAQSAARMFFKRLTAEGISFNPAVFGITRGEAAKLATLAGKIFKGLNDGQVKPEVKPTPKAEPKAERKAPKRSGMSNKDLCYDMFKTVNMSNGAARRAVIDMIVREFGFNKASVQSYASNFRKEFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCP2</accession>
    <name>A0A0A7HCP2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_089</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209831.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636251"/>
    <dbReference type="KEGG" id="vg:26636251"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="100" mass="11620" checksum="BF185F7614C4786A" modified="2015-03-04" version="1">MKQRLREDIASASNTGLLNFIKGAELIGKIHGCDDYSQDIPDWNQIIKIVERREQASKNVPNCPECGTEQVQLTYWRSSPLQYKCRHCKHRFEREENGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCP7</accession>
    <name>A0A0A7HCP7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209841.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636261"/>
    <dbReference type="KEGG" id="vg:26636261"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018775">
        <property type="entry name" value="RlaP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10127">
        <property type="entry name" value="RlaP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="336" mass="38854" checksum="3047849B0BE97DE1" modified="2015-03-04" version="1">MRTVMKGYFGSHLYGTSTPESDVDFKEIFVPHPRDILLGTAMNHTNLNTNNTATKNTKDDVDHELYSLKYFFKLAAEGETVALDMIHTPANLVVKSDLPDVWKFIQDNRSRFYTTNMKAYLGYVRKQASKYGVKGSRLAALRGVLAIVNQIPEQWVDYQEDGSTKQRRTKVEDIKHRLPENEFCEWVFHNHEKTGPQTFYTVLGRKYQTTLSLIELKQSLNKLDAEYGERARKAEANEGIDWKALSHAYRAGYQLKEIYQAGDLQYPLRTAPFILEIKQGLHAFKDVQAELEAIVDEVETNAVWAAKNGMPDKVDMKFWDKFVEEVYLDNHNSYYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCQ3</accession>
    <name>A0A0A7HCQ3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tail tube protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209925.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636345"/>
    <dbReference type="KEGG" id="vg:26636345"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010667">
        <property type="entry name" value="Phage_T4_Gp19"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06841">
        <property type="entry name" value="Phage_T4_gp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="163" mass="18640" checksum="BF77A23C190B2773" modified="2015-03-04" version="1">MELTDITRAFESGDFARPNLFEVEIPFLGKNFAFHCKAAPMPAGIVEKVPVGYMNRKINVAGDRTFDDWTITIYNDDAHKVRQAIVDWQNMCHGMTNEITGAAPADYKKTATVRQFHRDGKTITKEVVITGMWPTNVGEVQMDWDSNNEIETFETTFAIDWWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCS6</accession>
    <name>A0A0A7HCS6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Recombination, repair and ssDNA binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">uvsY</name>
        <name evidence="1" type="ORF">VR25_203</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209945.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636365"/>
    <dbReference type="KEGG" id="vg:26636365"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021289">
        <property type="entry name" value="UvsY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11056">
        <property type="entry name" value="UvsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="144" mass="16742" checksum="EC8EFBEAAAEAD280" modified="2015-03-04" version="1">MKTEIEYKLEVFQDELDADLKIDGTQIQYETQNNVLLHSKWLRLYTNCKKEIMRLEIQKKTALKKRLDHYTGRGDPGEEVCMDVYEKSELKTVMAADSSVLKIDTSIQYWALLQDFCSAALDGVKSRSFALKHMLEIRQFEAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCU3</accession>
    <name>A0A0A7HCU3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_149</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209891.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636311"/>
    <dbReference type="KEGG" id="vg:26636311"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="98" mass="11129" checksum="BA4E8C5A1479FCB8" modified="2015-03-04" version="1">MFNAPAWHATQAQEENKAIISAKIEAQLNELCETASEEVVAIIKQYPASNYSLACIKTEMVNLWRKNKKTFLGMQYQAIASAVVNMYDFEVYFPTSEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCU8</accession>
    <name>A0A0A7HCU8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative internal head protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ip6</name>
        <name evidence="1" type="ORF">VR25_154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209896.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636316"/>
    <dbReference type="KEGG" id="vg:26636316"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="77" mass="8969" checksum="A2B6BED8D35BE34A" modified="2015-03-04" version="1">MKTYQEFINETADVKVQFIYTGKKDKMGEMPYGTLRDALDNYGQLGGEEFGDYFVIQGPAEVIEKWANKYKSIFRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCW0</accession>
    <name>A0A0A7HCW0_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Head completion nuclease</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">During phage morphogenesis, plays an essential role in the head-tail joining step. The associated nuclease activity is essential for morphogenesis, possibly by cleaving packaged DNA to enable the joining of heads to tails. Displays both exo- and endonuclease activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Caudovirales head completion nuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209906.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636326"/>
    <dbReference type="KEGG" id="vg:26636326"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04160">
        <property type="entry name" value="NUCL_HEAD_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046390">
        <property type="entry name" value="NUCL_HEAD_T4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="149" mass="17723" checksum="F91C0CDB6D1BE868" modified="2015-03-04" version="1">MAYSGKFKPTNIEKYKGDWKKIQYRSSWEAWLMRWLDNHPNVVQWGSETVIIPYFSNADGKKRRYYMDFWVKFDTGQQFFFEVKPLKETRPPTKPVNNTAASKKRFINEMYTWAVNSDKWKAAQSTADKMGITFRIITENSLKKLGWKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCX4</accession>
    <name>A0A0A7HCX4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209960.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636381"/>
    <dbReference type="KEGG" id="vg:26636381"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020112">
        <property type="entry name" value="DUF2883"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11097">
        <property type="entry name" value="DUF2883"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="74" mass="8664" checksum="8E611D1CD656031E" modified="2015-03-04" version="1">MNNKNVYLGCPDWSHNKLEELMQELRTVGRFSGLEFPFQDTLQHGKSCIQVHILKQLSKTKDSATHYKLQRAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCY1</accession>
    <name>A0A0A7HCY1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tail sheath stabilizer and completion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209921.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636341"/>
    <dbReference type="KEGG" id="vg:26636341"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2000.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031997">
        <property type="entry name" value="T4-gp15_tss"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038553">
        <property type="entry name" value="T4-gp15_tss_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16724">
        <property type="entry name" value="T4-gp15_tss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="291" mass="33890" checksum="A55A86B440D0E10B" modified="2015-03-04" version="1">MFGHFYNSSLRRYIVLMGDLFSHVQVARTREDTGLKYIKVPISYASKEKFMMQLGKWTAIQNTPTPDMSPQERAAQKAKIETVLPRMNLHLVDLMYNGQYKTALQNHTQARFANNDPRKQISQYSPVPVKMIFELGIYTRHQDDMFQIIEQIMPYFQPHFNTTITELYTNEITFERDIRIVLQSIAMDEQIEGDAMTRRRLEWSIMFEVNGWLYPPVKEVAGEIRTIYLDFFANSRELAPEGNFESVDSEAVPRDVDQEDWQGESVQTYSQDIPVPVDPAPPAPRKNRVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCY2</accession>
    <name>A0A0A7HCY2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209970.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636390"/>
    <dbReference type="KEGG" id="vg:26636390"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="77" mass="8998" checksum="732D432CADCE123B" modified="2015-03-04" version="1">MKFRMVKISGLSSRGTGIIAFSVEYKKNFFSRWKSYYKSEWIDESIKYKTDPVFEKCKNLLSALKSRGTTTIKTVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HCZ7</accession>
    <name>A0A0A7HCZ7_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thymidylate synthase</fullName>
            <ecNumber evidence="3">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">td</name>
        <name evidence="10" type="ORF">VR25_248</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thymidylate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="3"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209990.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636410"/>
    <dbReference type="KEGG" id="vg:26636410"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="PTHR11548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="SSF55831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylat_synt" evidence="9">
        <location>
            <begin position="2"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AIZ02592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="286" mass="32891" checksum="20802E3EB604C9F2" modified="2015-03-04" version="1">MKNYQDLIQTVFDIGYQTDDRTGTGTIATFGTKVEWDMSEGFPATTVKRLAYKSVVGELLWFLEGSTNVERLREITHGPDSDKKTIWDQNFEAQGRALGYVDGELGPVYGKQWRDFGGVDQLVETIEKVKKVPTDRRQIVSAWNPAELKQMALPPCHLLYQFNVHDGELDLLWYQRSVDVFLGLPFDIGSYGTLLHIVAKMTRLKPGKLVFMGGNTHIYLNHIEQCKEVLRREPKTLPTLKINWPEQFQLWDTEMQLYWVTRHMSPGDFVLENYEPHPTIPAPMAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD00</accession>
    <name>A0A0A7HD00_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209936.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636356"/>
    <dbReference type="KEGG" id="vg:26636356"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="87" mass="10179" checksum="6F930CDA3A5D44B1" modified="2015-03-04" version="1">MTFAEELRQMAKESQDKVANDFIVIFRKVAIAAAENGKDAVNMAVSEKEYEEGNRTKISDFLRAEKFTSFTWNYNWQENKPTLYVKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD01</accession>
    <name>A0A0A7HD01_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uncharacterized 8.8 kDa protein in frd-Gp32 intergenic region</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209995.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636415"/>
    <dbReference type="KEGG" id="vg:26636415"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008765">
        <property type="entry name" value="Phage_T2_Frd3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05798">
        <property type="entry name" value="Phage_FRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="75" mass="8947" checksum="86938494F4C76043" modified="2015-03-04" version="1">MAKVNIDIVDFEYTYEVIRNRYPSLSMTYIKDTQFFSIQIEVQGPLEDLTRFMTDEYCDGMHVEDAEFYMGLIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD15</accession>
    <name>A0A0A7HD15_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Baseplate wedge subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209946.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636366"/>
    <dbReference type="KEGG" id="vg:26636366"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007048">
        <property type="entry name" value="IraD/Gp25-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04965">
        <property type="entry name" value="GPW_gp25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GPW_gp25" evidence="1">
        <location>
            <begin position="28"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="129" mass="14460" checksum="7E0C1A7FEA771177" modified="2015-03-04" version="1">MNINKMYSDVPPDLSMSWDKDVAKVTGARSVKNSLLGIITTRKGSRPFMPEFGCDISNQLFENITPLITDTIKRNIVSAVRNFEPRISNLQVAVVPMYDDNSIIVTVQFSIVDDPDTLEQIRIQLSQNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD61</accession>
    <name>A0A0A7HD61_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209966.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636386"/>
    <dbReference type="KEGG" id="vg:26636386"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="53" mass="5789" checksum="FE1923AC0EE8B7C1" modified="2015-03-04" version="1">MAKKEVKVVDGSSKRAGYKRASNKRINQVTDKLQARARAVLRADAACFGKPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD76</accession>
    <name>A0A0A7HD76_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA ligase 1</fullName>
            <ecNumber evidence="2">6.5.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Rnl1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rnlA</name>
        <name evidence="8" type="ORF">VR25_244</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in countering a host defense mechanism which, following viral infection, activates the host anticodon nuclease and shuts off viral translation. Repairs 5'-PO4 and 3'-OH groups in the cleaved host tRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions that perform the catalytic activity via a two-metal mechanism. One of the catalytic Mg(2+), which is coordinated by 5 water molecules, engages the lysine nucleophile and the ATP alpha phosphate while the Mg(2+) orients the PPi leaving group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tequatrovirus RNA ligase 1 family.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.3" evidence="2"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209986.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636406"/>
    <dbReference type="KEGG" id="vg:26636406"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003972">
        <property type="term" value="F:RNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042245">
        <property type="term" value="P:RNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04149">
        <property type="entry name" value="RNALIG_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019039">
        <property type="entry name" value="RNA_ligase_T4-Rnl1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012648">
        <property type="entry name" value="Rnl1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09511">
        <property type="entry name" value="RNA_lig_T4_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02308">
        <property type="entry name" value="RNA_lig_T4_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1259">Evasion of bacteria-mediated translation shutoff by virus</keyword>
    <keyword evidence="2" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="1 2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0692">RNA repair</keyword>
    <feature type="domain" description="RNA_lig_T4_1" evidence="7">
        <location>
            <begin position="53"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="2 3">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2 4">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2 4">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2 4">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2 4">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2 4">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2 4">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2 5">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Essential for RNA ligase activity" evidence="2">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="site" description="Essential for RNA ligase activity" evidence="2 6">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR612648-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR612648-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR612648-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR612648-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AIZ02588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="378" mass="43505" checksum="912D498356295291" modified="2015-03-04" version="1">MIELYDNLMKLCAESEKGKFFYTDFVSPFETKFRIFSYNYASYSDWLLDDALECRGIMFEMDADGPVRIAARPMEKFFNLGENPLTMNINMDEVALVMTKADGSLVSTYMDQTNIAFKSKGSIKSSQAAEALQVFKQEHRIAFRERVTEITEAGYTCNMEYVAPTNRIVLPYQERDLILLNVRHNETGEYIPYQDLFKDAALRPFLVEAYDPATIENVRDMKEIEGFVYELVDGRKFKVKTEWYCALHHTKDSVNNNQRLFEVVVAGGADDVIAMFTGDDYAREKVNAFTLTHLDYLSNTLGLLLDAQKQLAGKDRREFAIKGQELCKPYPGLFSVLMNTYQRPQETEQTIAQINNVFLKNHKLYIPADYQADVIMPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HD87</accession>
    <name>A0A0A7HD87_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Late transcription coactivator</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">RNA polymerase-associated protein Gp33</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">VR25_259</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Activates transcription at late promoters when the sliding clamp is present. Binds to both the host RNA polymerase (RNAP) and the upstream dsDNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with the beta subunit of host RNAP RpoB (via flap domain). Part of the transcription activation complex containing host RNAP, the viral RNA polymerase sigma-like factor, the coactivator gp33, and the sliding clamp.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The C-terminus is involved in transcriptional enhancement.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tevenvirinae late transcription coactivator family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210001.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636421"/>
    <dbReference type="KEGG" id="vg:26636421"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04165">
        <property type="entry name" value="T4_TRANSCR_COACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046384">
        <property type="entry name" value="LTACT_myovirus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031836">
        <property type="entry name" value="Trans_coact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042071">
        <property type="entry name" value="Trans_coact_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16805">
        <property type="entry name" value="Trans_coact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with host RNAP" evidence="1">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in transcriptional enhancement" evidence="1">
        <location>
            <begin position="91"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="97" mass="10868" checksum="0D1EBAC37D2777F7" modified="2015-03-04" version="1">MMSSLVNFDTQKTESPSGAISKQQNGLDIEAMVESTEMSYLEATTAWLEERGVPEGNFARYIPAGIIDKIMNEAYDDNLLRPSMSRTQKTNTLDFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDA7</accession>
    <name>A0A0A7HDA7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210031.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636451"/>
    <dbReference type="KEGG" id="vg:26636451"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="91" mass="10608" checksum="402911B81B314AA0" modified="2015-03-04" version="1">MEHVTTHHIKQILIQALKNNNINFPTHEIFDVVFNEVQGQVAYYDVIVYLSEFEVYHLTEIAFYLYRGTADFTGVVNAVGAYKEVKEQMHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDD7</accession>
    <name>A0A0A7HDD7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_002</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209744.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636164"/>
    <dbReference type="KEGG" id="vg:26636164"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="67" mass="8194" checksum="4B1DF8C3B7BCDC93" modified="2015-03-04" version="1">MTNFKVNLELFDKVVHKEYRVIQRFFDIREAEEFKERFKEIRIKIASDTATKDELLEVADLFKRNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDF3</accession>
    <name>A0A0A7HDF3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative anti-sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">srd</name>
        <name evidence="1" type="ORF">VR25_017</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209759.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636179"/>
    <dbReference type="KEGG" id="vg:26636179"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="248" mass="28795" checksum="C2313B1C82538D77" modified="2015-03-04" version="1">MTLSKTKTLKVKRRLEHTQASAKRRGKDFNLDFNYLVNILDQKVCAYSGEAFNNSIEDEKLSLERFNNDIGYIKGNVIPVKKKYNTMRSDWSLDELKQRRDDVAVKIARPSAKKIEKLNLTSEKWEQIKKSYNHIKNIQHKRGNRVKHYAQMSKSEQSKENQLKMVALKARIDGSRIAEGHELTKLNVLLKGNDWKVTKKLTNAETLFDCYDKIIQGLERFEKIGFIGKLKLKRGLPLNASIFKLIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDG9</accession>
    <name>A0A0A7HDG9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209774.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636194"/>
    <dbReference type="KEGG" id="vg:26636194"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="66" mass="7414" checksum="B9951D10C74B54E6" modified="2015-03-04" version="1">MGTLFYQIWKLTSKKDKKLIMGFLALDIFLWNLLVVPIAATQGVHLPQVTMGHIHSIIGYFTGIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDI6</accession>
    <name>A0A0A7HDI6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RecA-like recombination protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">uvsX</name>
        <name evidence="6" type="ORF">VR25_047</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecA family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209789.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636209"/>
    <dbReference type="KEGG" id="vg:26636209"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RECA_2" evidence="5">
        <location>
            <begin position="30"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AIZ02391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="392" mass="43980" checksum="A044EA40B1E38DB4" modified="2015-03-04" version="1">MSIADLKSRLIKASTSKMTATLTKSKFFNDKDVVRTKIPMLNIAISGALDGGMQSGLTIFAGPSKHFKSNMGLTMVSAYMNKYPEAICLFYDSEFGITEAYLRAMKVDPERVIHTPIQSVEQLKVDMVNQLEAIERGEKVIIFIDSIGNMASKKETEDALNEKVVGDMTRAKSLKSLFRIVTPFFSIKDIPCVAVNHTIETIEMYSKTVMTGGTGVMYSADTVFIIGKRQIKETGKELEGFQFVLNAEKSRMVKEKSKFFIDVKFDGGIDPYSGLLDMAMEIGFVVKPKVGWYNREYLDVETGEMVREEKSWRAKDTNCTEFWGPLFKHEPFRDAIKRHYQLGAIDSNAVVDAEVDELIASKVEKYSAPVGKTKPSAADIENDLDMMEDLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDN1</accession>
    <name>A0A0A7HDN1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nrdC</name>
        <name evidence="3" type="ORF">VR25_087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209829.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636249"/>
    <dbReference type="KEGG" id="vg:26636249"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="2">
        <location>
            <begin position="12"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="87" mass="9983" checksum="173372AA7B447303" modified="2015-03-04" version="1">MFKVYGYDSSIHRCVFCDNAKRFLDVKKQPYEFINVMPEKGVFDDEKIAQLLAALGRESQIGLTMPQVFAPDGSHIGGFTELREYFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDP2</accession>
    <name>A0A0A7HDP2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209839.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636259"/>
    <dbReference type="KEGG" id="vg:26636259"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="94" mass="9633" checksum="45F60FCDDE3A4EB0" modified="2015-03-04" version="1">MKLKLKVAIGLLAAVMSFGVLATEGTSGPGGQGSSQSAGPSNGSAHASHSQGIENIKSSYVNTTHGKAQEAWAKGRVVTDSVFCHMPKYVGCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDP6</accession>
    <name>A0A0A7HDP6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_102</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209844.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636264"/>
    <dbReference type="KEGG" id="vg:26636264"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="71" mass="7874" checksum="46CA84818C99104F" modified="2015-03-04" version="1">MLYDPSGNSENGIIVLEPEHPTGDVYRTVEVCECNFVEGNTGGISIEQDDDVIYLDASQVEALYSILKHNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDQ1</accession>
    <name>A0A0A7HDQ1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_107</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209849.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636269"/>
    <dbReference type="KEGG" id="vg:26636269"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="67" mass="7627" checksum="3568A7593BA24923" modified="2015-03-04" version="1">MRIKNIKIDAVNTGDEVVIYLNDYAIFMDRATDEEVVELLQKAPFELCEEDATHLSSAIFSLSYVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDS1</accession>
    <name>A0A0A7HDS1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease V N-glycosylase UV repair enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">denV</name>
        <name evidence="2" type="ORF">VR25_127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209869.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636289"/>
    <dbReference type="KEGG" id="vg:26636289"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004260">
        <property type="entry name" value="Pyr-dimer_DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021143">
        <property type="entry name" value="Pyr-dimer_DNAGlyclase_EndonucV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024796">
        <property type="entry name" value="T4_endonuc_V"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03013">
        <property type="entry name" value="Pyr_excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500103">
        <property type="entry name" value="EndoV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001000">
        <property type="entry name" value="PDG_ENDV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001000-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="138" mass="16214" checksum="F208902DA9AD5FAD" modified="2015-03-04" version="1">MTRINLTLVSELADQHLMAEYRELPRVFGAVRKHVQNGKKVSDFKIPSSFLLGTGHVTFFYDKLLFLKNRHQELIAECLKRGFNIKDISTQDLNDIPDEWKNDYQPSIWSIEISQSRLNEKISQKPTWYKYYGKAVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDS5</accession>
    <name>A0A0A7HDS5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209874.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636294"/>
    <dbReference type="KEGG" id="vg:26636294"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="195" mass="22135" checksum="0182E56255F53559" modified="2015-03-04" version="1">MALYEPGCMGIDANFIRRSENAGIIIPSGENMIIKKSWRNLDDGDEGIAASTVDWSGCNYNMKELLIKEFRMGYIVNGWQPEPLKEQTPDPLISYSKKYGFRTWKDEFDKLICSRFYAWSGILFLPILLFFLTGKNEAPVAVMGACISSAAVGLIASFLWTMTIEVPFRISKVKKVYDDIAKKNTLNSFIEECRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDT1</accession>
    <name>A0A0A7HDT1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_142</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209884.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636304"/>
    <dbReference type="KEGG" id="vg:26636304"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="96" mass="10747" checksum="94787698D19504FA" modified="2015-03-04" version="1">MNKIEIAIPKYYDEKSAEKAIYSLLNKTSEIETHCEEIADEYGIEFSTGDYGTGRTYHPVGYECSEWFTHHIEANGGKVENGVVTVGAWVSSSEMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDV8</accession>
    <name>A0A0A7HDV8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209909.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636329"/>
    <dbReference type="KEGG" id="vg:26636329"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="179" mass="19779" checksum="498CB5470BF8F74B" modified="2015-03-04" version="1">MANILPMSADLGDSMEGASIDVTFTAQLETNETLVEINITEYEATPGVNVEGNHLYGVYESVFGFADDALKYRLNDEFKTAGSWEDLPADKSTQLYLWRAPASLQKVFSYTVTLTYDFQEESSGGDTGNSGGSNSRAGNETNPPPAPVRKTMTKVYTKTIVGNWSRWADKLRSYVYARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDW9</accession>
    <name>A0A0A7HDW9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Neck protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209919.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636339"/>
    <dbReference type="KEGG" id="vg:26636339"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="312" mass="34791" checksum="905C808086BEF4D8" modified="2015-03-04" version="1">MATESYNPKQLKDAILRRLGAPITNIEVTTEQVYDCIQRALELYGEYHYNGYNKGYQAFYIGHDEVSQQKFRDGVFDLKGRNIFAVTQIIRTNVGSLTSMDGQATYPWFTDFVLGLAGINGGMGSSCNSFGPNAFGADLGYFTQLMQYRSMMQDLMVPLPDYWYNDDTEQLKIMGNFRQGDVIVIEVYTKSFNGVDAMASNTAGYGYASGDCSNPWNTGAQWDNPARRISGMRAGEDLGLQDGAYNNRWVKDYATALVKEVNGNVLAKHQGMMMPGGVTVDGVRLIEEARMEKERLREELDLLDAPTPILVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDY2</accession>
    <name>A0A0A7HDY2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Prohead core scaffolding protein and protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_187</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209929.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636349"/>
    <dbReference type="KEGG" id="vg:26636349"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005082">
        <property type="entry name" value="Peptidase_U9_T4_prohead"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03420">
        <property type="entry name" value="Peptidase_S77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="212" mass="23099" checksum="EA9B57BFAFC6F06B" modified="2015-03-04" version="1">MEQKPELLIEHWGQPGEIKDGVPMLESHDGSSSGLKPGLYIEGIFLQAEVVNRNKRLYPKRILEKAVADYIAEQVETKQSLGELNHPPRANVDPMQAAIIIEEMWWKGNDVYGRARIIEGDHGPGDKLAANIRAGWIPGVSSRGLGSLTKSAKGYNIVNEGFKLTVGVDAVWGPSAPDAWVKPKQITESQTAEADTSADDAFMALAEALKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HDY9</accession>
    <name>A0A0A7HDY9_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Capsid vertex protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">gp24</fullName>
        </alternativeName>
        <component>
            <recommendedName>
                <fullName evidence="1">Mature capsid vertex protein</fullName>
            </recommendedName>
            <alternativeName>
                <fullName evidence="1">gp24*</fullName>
            </alternativeName>
        </component>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Capsid protein that self-associates to form pentons, building the capsid in association with hexamers of the major capsid protein and one dodecamer of the portal protein.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homopentamer. Interacts with the portal protein. Interacts with the major capsid protein that forms hexamers.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Capsid vertex protein</molecule>
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Part of the icosahedric capsid shell of the immature virion.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Mature capsid vertex protein</molecule>
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Part of the icosahedric capsid shell of the mature virion.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">A proteolytic cleavage gives rise to the mature capsid vertex protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Tevenvirinae capsid vertex protein family.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209934.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636354"/>
    <dbReference type="KEGG" id="vg:26636354"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019028">
        <property type="term" value="C:viral capsid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04113">
        <property type="entry name" value="CAPSID_P_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038999">
        <property type="entry name" value="CAPSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010762">
        <property type="entry name" value="Gp23/Gp24_T4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07068">
        <property type="entry name" value="Gp23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="1" id="KW-0426">Late protein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_5023245328" description="Capsid vertex protein" evidence="1">
        <location>
            <begin position="1"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023245329" description="Mature capsid vertex protein" evidence="1">
        <location>
            <begin position="11"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage" evidence="1">
        <location>
            <begin position="10"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="427" mass="46783" checksum="4E0CFBA29C9C2E32" modified="2015-03-04" version="1">MQKINALIHESTLTAANQVARPNLLSYTRATNKRIFKALVAEQKTTQPVAALYGVRVLNPDDKMTYLGGATFAGQIGMFERKNIPEFTNKDEAYAVGNMFQFESIVFKALEASPFAGTLETDLGEVISEAIAAGHIRMMSDAAFTDKFEQGHPEIAEAGFRIDKWQTEVKSRKLKTSLTVELAQDLEANGFDATDFIDNILGIQMAEEINKDVLQSLITVSSRFKVQGVSEKGVLNLTDAAYDNAQDRARTLYYYMCEMNSAVQRQTSFAGTYAVASSRCAAILAASGWVEKKEDQDELAYGVLKNGLPLYADMNSPCDYVIVGVNADMGEGQTVASLYYAPYTEGLSEVDDEGDTSVGEFKVIVDPESLQPTVALLARYALTANPYTVAKDDKEARIIDGADMDKMANQSQLSSYLGVKLPPLEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE49</accession>
    <name>A0A0A7HE49_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_222</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209964.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636384"/>
    <dbReference type="KEGG" id="vg:26636384"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009690">
        <property type="entry name" value="Phage_T4_Gp30_7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06919">
        <property type="entry name" value="Phage_T4_Gp30_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="121" mass="14146" checksum="26F4350B524656A3" modified="2015-03-04" version="1">MNYINFERKYVSNCIPGSSEVICLWKHKNGSVCEIEQYMTPNYVYMRFENGITLSITMTGSNFKIALDDDFRERDLGTHPCWNGVNRKLLVKTWIRHILGNKAKPEHLEAIFDVVLNEFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE57</accession>
    <name>A0A0A7HE57_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polynucleotide kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pseT</name>
        <name evidence="1" type="ORF">VR25_237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209979.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636399"/>
    <dbReference type="KEGG" id="vg:26636399"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047846">
        <property type="term" value="F:deoxynucleotide 3'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044493">
        <property type="entry name" value="PNKP_C_HAD"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00010">
        <property type="entry name" value="C1.8:_polynucleotide_5'-hydrox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="302" mass="35159" checksum="75593559584DEC12" modified="2015-03-04" version="1">MMKRIILTVGCPGSGKSTWAREFIAKNPGYFNVNRDDYRQSIMGHEERDEYKYTKKKEGIVTCMQFDTAKGILYGGDSVKGVIISDTNLNPERRLAWETFAKEYNWKIEYKVFDVPWTELVKRNNKRGTKAVPIDVLRSMYSHMRAYLGLPVYTGTPGKPKAVIFDVDGTLAKMVDRSPYDLEKCDTDIINPMVVELSKMYDKQGYQIIVVSGRECGTEEDPMKYYRMTRKWVEDFAQVPLVMQCQRVQGDDRKDDVVKEEIFWEKIAPHFDVKLAVDDRQNVVEMWRRIGVECWQVAFGDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE62</accession>
    <name>A0A0A7HE62_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inhibitor of host transcription</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">alc</name>
        <name evidence="1" type="ORF">VR25_242</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209984.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636404"/>
    <dbReference type="KEGG" id="vg:26636404"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039653">
        <property type="term" value="P:suppression by virus of host transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020367">
        <property type="entry name" value="Host_transcript_inhib_Alc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17527">
        <property type="entry name" value="ALC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="167" mass="19127" checksum="14C0031B597DF08E" modified="2015-03-04" version="1">MNMQLISNDMIVDVYGDRHDGIYVYKGSKNVGFLTDLRKKLASDNKLKTKQKEYRNKKSEERKEALHESVPEMVDFLKNHLVKYDAEVFINQTQPNVHINGCVCYVVVEPLTLQHRLGIKHPVLTQDDMADEVGNQFRISASDSTNHILLNGLSQDDIVEVIIKLCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE86</accession>
    <name>A0A0A7HE86_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoid disruption protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ndd</name>
        <name evidence="6" type="ORF">VR25_282</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Disorganizes the host nucleoid and inhibits replication, but without host DNA cleavage or degradation. Only the architecture of the nucleoid is affected. May act on the host chromosomal sequences that determine the structure of the nucleoid. Binds to dsDNA but not to ssDNA.</text>
    </comment>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210024.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636444"/>
    <dbReference type="KEGG" id="vg:26636444"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098673">
        <property type="term" value="P:inhibition of host DNA replication by virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060153">
        <property type="term" value="P:modulation by virus of host cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009514">
        <property type="entry name" value="Phage_Ndd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06591">
        <property type="entry name" value="Phage_T4_Ndd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="4" id="KW-1248">Inhibition of host DNA replication by virus</keyword>
    <keyword evidence="3" id="KW-1121">Modulation of host cell cycle by virus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AIZ02626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="149" mass="16749" checksum="F41A8CE161943913" modified="2015-03-04" version="1">MTTYMTRRDVLNAGATTIAYIHNGNYVAGRPTKEAITQPGFYFVVKGEGESRIVAARFYVGNQRSQQGFDTVLSHIRKQRSQLSRTMANNGVIYEVLFVPVSKMKPLTTGYGKGQIAMAFTRSHSSDCQTLSEMNRMLADNFKFILQSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HE88</accession>
    <name>A0A0A7HE88_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210029.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636449"/>
    <dbReference type="KEGG" id="vg:26636449"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="27" mass="3073" checksum="491B586128E055B9" modified="2015-03-04" version="1">MSSKNWCLIWVLSIPMICVCFSLLITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFP6</accession>
    <name>A0A0A7HFP6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protector from prophage-induced early lysis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rIIA</name>
        <name evidence="1" type="ORF">VR25_001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209743.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636458"/>
    <dbReference type="KEGG" id="vg:26636458"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="744" mass="84276" checksum="6B0EEA5791D68461" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFQ0</accession>
    <name>A0A0A7HFQ0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209748.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636168"/>
    <dbReference type="KEGG" id="vg:26636168"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="86" mass="9215" checksum="D495C127B91D56D0" modified="2015-03-04" version="1">MKYVNRSITALVLAVSLVGCTDADNATKVLNANGFEQIQITGYSLFGCSEDDFQRTGFTAVGPTGKQVKGTVCSGLLFKNSTIRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFQ4</accession>
    <name>A0A0A7HFQ4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209753.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636173"/>
    <dbReference type="KEGG" id="vg:26636173"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020230">
        <property type="entry name" value="Tscrpt_reg_MotB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17613">
        <property type="entry name" value="motB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="251" mass="28822" checksum="D52BC6ABC0AEB085" modified="2015-03-04" version="1">MKPEFIDFDITSMYVRPIKPLKLEKQNMTIEINKTYHLIEPIIQNAAMISGYNTLTDALGEGEFVVETFVKSNWFDKAYILHARRLDTNEVEKIMVYEAEIQLFKEVEETPIKVGKTYQLIEDDSQFGKTVALHAGWRVLKGIFGFAPFTVKTVKYSTHLNIFEFTAVNESDEHLEAILYPRESVLLKEVSELGDPVDLLCKPVQIKRPFNSSICGWVTDQWIEDGVELLNVVHVGEFTVVPRSMVVQIFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFR1</accession>
    <name>A0A0A7HFR1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209763.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636183"/>
    <dbReference type="KEGG" id="vg:26636183"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="58" mass="6744" checksum="7F7B69BF9AA842F9" modified="2015-03-04" version="1">MDLFELFEEPKAHTEARVDLVDELDAIIQKHGFSLPMEVLRDLASYYDDPPPWAPWGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFT2</accession>
    <name>A0A0A7HFT2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209783.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636203"/>
    <dbReference type="KEGG" id="vg:26636203"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="110" mass="12384" checksum="75EF8F885E4C4E11" modified="2015-03-04" version="1">MITDKVEVTLVITPLGFPAYNRVVSLHPAGIHWYAHKTADTHNAKVEAFVNGKCHHKIDLRKGAALRSLILAVESQLENEEICISDIEFALYNAREEYYKMTGQSVEGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFV7</accession>
    <name>A0A0A7HFV7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_066</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209808.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636228"/>
    <dbReference type="KEGG" id="vg:26636228"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="88" mass="10530" checksum="4DFD4D1F8B00F786" modified="2015-03-04" version="1">MHINHTMISVQDLGTFWVDEFMKITFFPHAEGYGSWESHISMLNEGQYRNEHDRLMEFISDAEVIPYIDIHEFKAIMEKVFQAYCLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFW7</accession>
    <name>A0A0A7HFW7_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209818.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636238"/>
    <dbReference type="KEGG" id="vg:26636238"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="71" mass="7942" checksum="169B011BF578635A" modified="2015-03-04" version="1">MNKFRNATADILANITLVLFIVCLLILAIPFGLLFVIIGWLSTNPGLESSEFNKRIQAIHNTIAKMLKVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFY5</accession>
    <name>A0A0A7HFY5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_096</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209838.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636258"/>
    <dbReference type="KEGG" id="vg:26636258"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="68" mass="7446" checksum="64130AE438343615" modified="2015-03-04" version="1">MLELIKAAGEKGLMVNTRDPEQRQAFGELKAKGLVKASLGIGNALRVTLTPAGKAMFFPKPLPKRRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HFZ1</accession>
    <name>A0A0A7HFZ1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209843.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636263"/>
    <dbReference type="KEGG" id="vg:26636263"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="184" mass="21231" checksum="3E45700D68D375B5" modified="2015-03-04" version="1">MIIEKSGLFGDLTADVIDNAIVLKQEDDTVVLTIQDIQNLYKLSVIDAEQYIRTHNRVFKINDEVAAWLYRGENGFNLETEWACLSIKNRSEFLEKIFKLFQEECVPELEWKIPGCDAIMHSSETFEGDEEGDYNTEFSVYQYQGRDMLSIIQTHDGEAEVVFTKDELKVLVKYLNTVIPTMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG07</accession>
    <name>A0A0A7HG07_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Valyl-tRNA synthetase modifier</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">vs</name>
        <name evidence="1" type="ORF">VR25_116</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209858.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636278"/>
    <dbReference type="KEGG" id="vg:26636278"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="119" mass="13093" checksum="4BBD1BAFA1EECE85" modified="2015-03-04" version="1">MVRVITLAIGLVFSTGGIASVQSDDNNSIIEYATRTAKDYCASSNVDCVIQFSAKLTAAYKDGQNDVEHTLMKKSILSNKYEKKLFEMDCILSSAKYKAACTSMVDRLVDSYNRGLNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG13</accession>
    <name>A0A0A7HG13_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209863.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636283"/>
    <dbReference type="KEGG" id="vg:26636283"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="72" mass="8172" checksum="E259C67983700C4B" modified="2015-03-04" version="1">MSKLTIEGSDAALKRFVEWFNGPGEQDFLEVWDGGQWNGKELVYPTTYISVQGWTDGLRLVEYDIATGEEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG30</accession>
    <name>A0A0A7HG30_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209878.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636298"/>
    <dbReference type="KEGG" id="vg:26636298"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="66" mass="7226" checksum="9422C63E8CE4C9C9" modified="2015-03-04" version="1">MSIANELIKVLNEAKANQLEVNLQEVSDGIKVTISGDGVPGTTEVCDTLEEVVSFVKRWTYLYGPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HG80</accession>
    <name>A0A0A7HG80_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Terminase, large subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">DNA-packaging protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="3">ATPase</fullName>
                <ecNumber evidence="3">3.6.4.-</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="3">Endonuclease</fullName>
                <ecNumber evidence="3">3.1.21.-</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="5" type="ORF">VR25_181</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">The terminase large subunit acts as an ATP driven molecular motor necessary for viral DNA translocation into empty capsids and as an endonuclease that cuts the viral genome to initiate and to end a packaging reaction. The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit involved in viral DNA recognition (packaging sequence), and a large terminase subunit possessing endonucleolytic and ATPase activities. Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine. The terminase large subunit exhibits endonuclease activity and cleaves the viral genome concatemer. Once the capsid is packaged with the DNA, the terminase complex is substituted by the tail.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">ATPase activity requires 1 Mg(2+) ion per subunit. Nuclease activity probably requires 2 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with the terminase small subunit; the active complex is probably heterooligomeric. Interacts with the portal protein.</text>
    </comment>
    <comment type="domain">
        <text evidence="3">The N-terminus contains an ATPase domain. The C-terminus contains an endonuclease domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Tequatrovirus large terminase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="3"/>
    <dbReference type="EC" id="3.1.21.-" evidence="3"/>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209923.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636343"/>
    <dbReference type="KEGG" id="vg:26636343"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098009">
        <property type="term" value="C:viral terminase, large subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019073">
        <property type="term" value="P:viral DNA genome packaging"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_04146">
        <property type="entry name" value="TERL_T4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035421">
        <property type="entry name" value="Terminase_6C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044267">
        <property type="entry name" value="Terminase_large_su_gp17-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17289">
        <property type="entry name" value="Terminase_6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0231">Viral genome packaging</keyword>
    <keyword evidence="3" id="KW-1188">Viral release from host cell</keyword>
    <feature type="domain" description="Terminase_6C" evidence="4">
        <location>
            <begin position="399"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Walker A motif" evidence="3">
        <location>
            <begin position="161"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Walker B motif" evidence="3">
        <location>
            <begin position="251"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="ATPase coupling" evidence="3">
        <location>
            <begin position="285"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="active site" description="For ATPase activity" evidence="3">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic; for nuclease activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="542"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic; for nuclease activity</note>
        </ligand>
    </feature>
    <feature type="site" description="Modulates nuclease activity" evidence="3">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_04146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AIZ02525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="610" mass="70086" checksum="680DC8E212274B76" modified="2015-03-04" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGA8</accession>
    <name>A0A0A7HGA8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Baseplate hub assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209948.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636368"/>
    <dbReference type="KEGG" id="vg:26636368"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024364">
        <property type="entry name" value="Baseplate_phage_T4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12322">
        <property type="entry name" value="T4_baseplate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="250" mass="29410" checksum="7E3A6F66FCED9DA2" modified="2015-03-04" version="1">MANIVRCEMPDGVHRFKPFTVADYRDLLLVRNDMNNKPVEEQKQLLDELLEDYFGEYPKAWRPYIFLKVFTSSIGKTKVPVAFECQKCKKTKQTLFNMSQGPLINPTMETAGIKIQFKFPEMEYKDKSELVLNTIQTVEDSEQKYNWEDLPEETKMQVIDAIDIESLEELLKKMHSIYLPFTYGCCEKHKTEYTDLLDVFKLILNPDEVFIFYQINHLLVKNQYSLDSIMHMIPIERGIALSLVEKDLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGD5</accession>
    <name>A0A0A7HGD5_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209767.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636187"/>
    <dbReference type="KEGG" id="vg:26636187"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="112" mass="12032" checksum="9A85A969DCD8AE11" modified="2015-03-04" version="1">MISWLKNLFKTKPGEGVVPIAPSDVKLREYVYMGDGMMEEVIRQPEKAGNVGVGALPLNSKKLKEHLDARRTSHIDTTSIVVTAAAVSSWTGDSSYSSYDSGSCDSSSSSCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGD9</accession>
    <name>A0A0A7HGD9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_216</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209958.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636378"/>
    <dbReference type="KEGG" id="vg:26636378"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="270" mass="31146" checksum="00018D90F6955857" modified="2015-03-04" version="1">MKPVILTDIDGVCLSWQSGLPYFAQKYNLPLEHILKMIQDEKFVTPGKLFNCDEELGAQLIEKYNCSDFIRYLSPYADALRVINNLKEQYDFVAVTALGDSIDARLNRQFNLNALFPGAFKEVMMCGHTASKEELFQKAKDKYNVICYIDDLAHHCDHASEILAVPVYWMARGERDAIPKTASKVFNWDDVAGQLKLKHKDEPTKPEFTPDELRKLEELFRETRRLQQQMQQGWQPGQPWTPGYNPAYPYQYGVGTGIEYWYNQPTCGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGE0</accession>
    <name>A0A0A7HGE0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleoside triphosphate pyrophosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209772.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636192"/>
    <dbReference type="KEGG" id="vg:26636192"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="173" mass="19955" checksum="EF8894BAEC7CAC48" modified="2015-03-04" version="1">MAHFNECSQLIAGVDKAEEAYFNALIHEDKDPLQVMLDMQKSLQVRLAKEKPEYNEHPDNLATAGEVVTWLRNQKDYIDDEFRELITALGGMSNGEKAASAVWKPWKAQHGEMQQTLINDLSPEDQLEIKFEMIDILHFVLNMFQGLGLTAEEIFKLYYLKNAENFARQDRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGE3</accession>
    <name>A0A0A7HGE3_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209963.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636383"/>
    <dbReference type="KEGG" id="vg:26636383"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="95" mass="10727" checksum="37BE02E174E37CF0" modified="2015-03-04" version="1">MFMTTYFDTRKNFCEVVFSKKGPNVPAGCEPTKESIKNYADIVCPVEFRTVNGRDTLAITKLSRDIDIDPISAREINSSDINGKNVKSRGFLTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGG9</accession>
    <name>A0A0A7HGG9_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209802.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636222"/>
    <dbReference type="KEGG" id="vg:26636222"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="339" mass="39330" checksum="86864BA0569F8263" modified="2015-03-04" version="1">MKILNLGDWHLGVKADDPWAQNIQRDGILQAIAYSKANGIKVWIQYGDIFDVRKAVTHKTMEFSREIMELLREAGITLHTIIGNHDMNLKNKIHPNAITELLNKYDHVKIYDKPTTVDFDGCQIDMIPWMCDENATAIHDHIKTSGAEYCIGHWELTGFYFYKGLKSHGLEPDFLKKYKQVWSGHFHTISEAANVKYIGTPWTLTAGDENDPRGFWEFNTETEEMKFIPNETTWHRKIFYPNETINYDDFKDLSVRVIVEKVDKELTKFESELEKRVHDLRIVNKVDNSVDTTDADEELDIKRLTDMMAEYIDALPDANEKESKALKALANKLYLEVQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGH0</accession>
    <name>A0A0A7HGH0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209998.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636418"/>
    <dbReference type="KEGG" id="vg:26636418"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004885">
        <property type="entry name" value="FRD2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03197">
        <property type="entry name" value="FRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="85" mass="9721" checksum="69E53A9CDE75D456" modified="2015-03-04" version="1">MQTFKTYTLNNLINEYKREDAKNCDMVNLINKNGGSFKVLSINKFMDTLIVDCVEFPNGVIASSDDFGVNCFEILDSEFKFFSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGI0</accession>
    <name>A0A0A7HGI0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210013.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636433"/>
    <dbReference type="KEGG" id="vg:26636433"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="65" mass="7520" checksum="1127BE6882BD2DCE" modified="2015-03-04" version="1">MKTLNSKSEYFNSLNSRDKETIKYFIVELGYTDVNMLSEHIIECGVAKRFSLTGGCLREVIAYYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGI4</accession>
    <name>A0A0A7HGI4_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">motA</name>
        <name evidence="3" type="ORF">VR25_276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210018.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636438"/>
    <dbReference type="KEGG" id="vg:26636438"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015241">
        <property type="entry name" value="MotA_Tscrpt_reg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036474">
        <property type="entry name" value="MotA_Tscrpt_reg_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015198">
        <property type="entry name" value="Phage_T4_MotA_Tscrpt_reg_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09114">
        <property type="entry name" value="MotA_activ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09158">
        <property type="entry name" value="MotCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69652">
        <property type="entry name" value="SSF69652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MotA_activ" evidence="1">
        <location>
            <begin position="3"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="MotCF" evidence="2">
        <location>
            <begin position="102"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AIZ02620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="202" mass="23001" checksum="AE745232519CAA3B" modified="2015-03-04" version="1">MNKLNYIVKCSQNALHETDVNALVFVYKNNFVRPEVVLDQQNTSIDSVQTLLNNNYVEASGDGLMITEKGVDLILDAAELWANENNPDLLEVKKTRTKRGVTDEMEATAEYIKEQLLSIGIDFKSISEDRSNLIVKFKRVKTLKQIDVRRDGQIRVHAYNTEQKIVKQFTDVGFSVKVGGLNTYIDNHMSTENIQHVINILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGJ6</accession>
    <name>A0A0A7HGJ6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210033.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636453"/>
    <dbReference type="KEGG" id="vg:26636453"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="89" mass="10181" checksum="1E1F440E96F9F1B9" modified="2015-03-04" version="1">MIKHFNVSDRDIKVSNLRGHHYAGTVYCGKLIKHEGDVHYGWLECDEVVVGEFPDPDSDTFDANDRLYYGELHIRGIVGIDEVQDDSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGK1</accession>
    <name>A0A0A7HGK1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209832.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636252"/>
    <dbReference type="KEGG" id="vg:26636252"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="330" mass="37565" checksum="3BE964889CE37751" modified="2015-03-04" version="1">MTRNEYIQAFNTTIDAKVKPLIGESAILSIINFWLNQIDASIVASGRFKKDIATIASRAGNADIKKTFKGSRVLAYLVNKDLLNKFGVESRRGKGTIGYHWFGDVEKYYLDKQGYTVSEFANSWAREFRNNKMSIIKSATKLMGGDFRTIYHLAENMVKVKDSGENQVIITVKHEFYTPEATPENIKKYLDVACTLTHQLQCALNYMHTVEKIKVDPITSSHGWKGWKIVVTLREVKCAKQPTDAEIYKKKSEEIMNAPQEVTTLEDLIDNLNNEPVKQKAPEIVALETAYNEALAVNKKATEDYTKAKRLWEESTNRLDKLEQALELLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGL8</accession>
    <name>A0A0A7HGL8_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209852.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636272"/>
    <dbReference type="KEGG" id="vg:26636272"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="91" mass="10810" checksum="75CAD0135AFD8210" modified="2015-03-04" version="1">MIYKIWTYISIFVIAGIAFIPTQTDSERYEREIEIVASTYHSVNKECPNKNGINLQKAHYMLTVTSPVQRIWVDRHFSDLFAIYCFKFKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGM2</accession>
    <name>A0A0A7HGM2_9CAUD</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Macro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209857.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636277"/>
    <dbReference type="KEGG" id="vg:26636277"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="159" mass="17583" checksum="8C697713D1062C42" modified="2015-03-04" version="1">MIVNYIKGDIVALFLEGNIIAHGCNCFHTMGSGVAGQLAKAYPKILEMDKTSTEYGSREKLGDMSIVFKHKPTGFGMCYNLYTQYEPGPNLDYGALVNCMIELNRQAESLLFKPVIYIPRIGCGIAGGDWDKVSRLIDMFTPDIDLVVVDYESTLSTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGN6</accession>
    <name>A0A0A7HGN6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nudix hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nudE</name>
        <name evidence="2" type="ORF">VR25_130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209872.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636292"/>
    <dbReference type="KEGG" id="vg:26636292"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="152" mass="17404" checksum="29A33F2CEF2DD155" modified="2015-03-04" version="1">MSKKNVVKELSAGIIFMTEDKELFMGRVTGSRKPGMPAHKWDIPKGHVEAGESPIEAAMRECEEETGFTRYDPAFLKDLGEFRYSDNKNLHLFLYTVPVEHEQFRHSKCSAYHTFPDGSSVPEFDAFALIKPSQWQYVMGKSMYKVLTQIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGP6</accession>
    <name>A0A0A7HGP6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209882.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636302"/>
    <dbReference type="KEGG" id="vg:26636302"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="65" mass="7328" checksum="ADF573BA2DA55556" modified="2015-03-04" version="1">MSRELDCAIRTAKAAIENVIQICKEEREEADIYISGVRDLDRHITLYNGCITISGTSWVSSSYEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGR0</accession>
    <name>A0A0A7HGR0_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209897.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636317"/>
    <dbReference type="KEGG" id="vg:26636317"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="99" mass="11420" checksum="270C30995EE0EB5B" modified="2015-03-04" version="1">MQTFHEFLVENNYLAEAKTWPLGLQKKNTYKWVDFKGKGDAEDFDQLRKNGYTFLDSNYNKITSFSQKSSIAYIETGKNTPKNITDDFAAYGVIRGSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGR6</accession>
    <name>A0A0A7HGR6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Deoxynucleoside monophosphate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209902.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636322"/>
    <dbReference type="KEGG" id="vg:26636322"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023191">
        <property type="entry name" value="DNMP_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="225" mass="25919" checksum="9DE53E8DFCBABE20" modified="2015-03-04" version="1">MKLIAIVGKKRSGKDTTADYVISQNGTKWQLAGPIKEALYKAWVRQDLPHNLTLENFDGQGYDREKTLIMNNTEAHILLVDALEWLKQQYNLDLPNPDMVRKIIEFHTLNNVEPWTVRRFMQTLGTDIVCTEFDSMFWIKTFACDYLDNLYSGYKYYVVPDVRQKNELDSLRAMGATIIFVERDEANHSTDTHITEAGLPPLASDIVIKNDGTLEELFDKINKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGT1</accession>
    <name>A0A0A7HGT1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Short tail fibers protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">VR25_175</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209917.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636337"/>
    <dbReference type="KEGG" id="vg:26636337"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098024">
        <property type="term" value="C:virus tail, fiber"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1070.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015173">
        <property type="entry name" value="Phage_T4_Gp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011083">
        <property type="entry name" value="Phage_tail_collar_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037053">
        <property type="entry name" value="Phage_tail_collar_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027448">
        <property type="entry name" value="Short_tail_fibre_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044916">
        <property type="entry name" value="Short_tail_fibre_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07484">
        <property type="entry name" value="Collar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09089">
        <property type="entry name" value="gp12-short_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14928">
        <property type="entry name" value="S_tail_recep_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="gp12-short_mid" evidence="2">
        <location>
            <begin position="253"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Collar" evidence="1">
        <location>
            <begin position="325"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="S_tail_recep_bd" evidence="3">
        <location>
            <begin position="420"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AIZ02519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="511" mass="53203" checksum="C32C75AB1E66A4C9" modified="2015-03-04" version="1">MTTTNTLKHISDKSEYKTFDPTGTSFPPSVTNVQEALGALAPIAIDGFIPESTVAVPGIIRLATEQEVIDGIGNNTAVTPETLKARLNIPTQATETVVGITRYATNAEAIDGTVTDAAIVPSSLKASIDNTFNTRTSTEDRNGVIKISTQAAALAGTDDTTAMTPLKVSLAIGAATAALPTYSTATTTIQGIVKIATPAEVQAGAMNNGVAVSPLGLISLTANASRRGLVQLASSAEAITGTDATKAITPQALQAKTGNTGRLGIVKLTTTVGSGDGNTALAYNANVISTTGGTINGTLNVNGTLRRNGQDVVTRNELKDSVPIGTIIMWGGQTGNIPSGWEICDGGNVGDAGFRNVVGSKWGATGNKPDFRGLFPRGSNSSNDGAMKEWETNINIRNAKGNDSKQKPKLGQGVGSYGHGTVQAQQLRFHKHAGGFGEHDNSGAFGNTVRSNYAGTRKGLDWDNRSYFTNEGYEIDGAGSRDSRTTLNSEGLIGNESRPWSMSILFIIKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGT6</accession>
    <name>A0A0A7HGT6_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Small terminase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209922.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636342"/>
    <dbReference type="KEGG" id="vg:26636342"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020342">
        <property type="entry name" value="Phage_T4_Gp16_DNA-pack"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11053">
        <property type="entry name" value="DNA_Packaging"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="163" mass="18088" checksum="64958D515052F6E5" modified="2015-03-04" version="1">MSELDINKLMDITDLPGIAGEEVTAYEPLVLKEVESNPNNRTPDLEDDYSVVRKNLHFQQQMLMDAGKIFLEAAKNAESPRHMEVFATLMGQMTTTNKELLKLHKEMKEITAEQIGTKGGAPSQTNIENATIFMGSPADLMDEVGDSYEAQERQEKIINGTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGU2</accession>
    <name>A0A0A7HGU2_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prohead core protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209927.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636347"/>
    <dbReference type="KEGG" id="vg:26636347"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035114">
        <property type="entry name" value="GP67"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17634">
        <property type="entry name" value="GP67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="84" mass="9582" checksum="C294651EC30F83FD" modified="2015-03-04" version="1">MDDLFEAIKSNDLVAVRKYFAENIGPVCGSLIEERKIEIARSIMIEGEEPKEDDENKDDKAEKKDKKESDDADEGDDDEDEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HGZ1</accession>
    <name>A0A0A7HGZ1_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009209957.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636377"/>
    <dbReference type="KEGG" id="vg:26636377"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021405">
        <property type="entry name" value="Phage_T4_Gp30.1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11243">
        <property type="entry name" value="DUF3045"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="92" mass="10853" checksum="924FFB9E18D9D3E4" modified="2015-03-04" version="1">MFVVHTISDRGPTTTMDYGHVNQFIRHVNHDYSFDINPAKDNPVWRECVEQGFIYVHFMTKMKPDGATKFVFSYHKRLDLLLEDVAYNRAND</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HH21</accession>
    <name>A0A0A7HH21_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210012.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636432"/>
    <dbReference type="KEGG" id="vg:26636432"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="93" mass="10709" checksum="DFB0D008E82D45B8" modified="2015-03-04" version="1">MITKLHTCKATELVILIDELFKIHAAVGDEIYAEILCDLDSSFGYIQPEYTIRFSSERPGYVKVTFGADLDEEQILREIQEEIDDFGLEDYID</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HH25</accession>
    <name>A0A0A7HH25_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">VR25_275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210017.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636437"/>
    <dbReference type="KEGG" id="vg:26636437"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AIZ02619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="58" mass="6875" checksum="5F16D6B054FE1C2F" modified="2015-03-04" version="1">MNIYLIKYLKDGKERDYQIPAKNEYDACVRLGQIHGDDREYRDDVEIEIQSVTLKVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-03-04" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0A7HH27</accession>
    <name>A0A0A7HH27_9CAUD</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">VR25_280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Escherichia phage vB_EcoM_VR25</name>
        <dbReference type="NCBI Taxonomy" id="1567028"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Duplodnaviria</taxon>
            <taxon>Heunggongvirae</taxon>
            <taxon>Uroviricota</taxon>
            <taxon>Caudoviricetes</taxon>
            <taxon>Caudovirales</taxon>
            <taxon>Myoviridae</taxon>
            <taxon>Tevenvirinae</taxon>
            <taxon>Gaprivervirus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2014-10" db="EMBL/GenBank/DDBJ databases">
            <title>VR bacteriophages - a small but diverse group of low-temperature viruses.</title>
            <authorList>
                <person name="Kaliniene L."/>
                <person name="Meskys R."/>
                <person name="Simoliunas E."/>
                <person name="Zajanckauskaite A."/>
                <person name="Truncaite L."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="KP007361">
        <property type="protein sequence ID" value="AIZ02624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009210022.1">
        <property type="nucleotide sequence ID" value="NC_028925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="26636442"/>
    <dbReference type="KEGG" id="vg:26636442"/>
    <dbReference type="Proteomes" id="UP000030717">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AIZ02624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000030717"/>
        </source>
    </evidence>
    <sequence length="55" mass="6235" checksum="F89C721DF92D2CC5" modified="2015-03-04" version="1">MTSVFSFIYLVAVIVLVTLFVAGVFIPPMWFVYFLCGWFVVDAFVKFMVSAVSND</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>