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<entry dataset="TrEMBL" created="2008-12-16" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>B6VDX7</accession>
    <name>B6VDX7_THCOV</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Replicase polyprotein 1ab</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="41">ORF1ab polyprotein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="53" type="primary">orf1ab</name>
    </gene>
    <organism evidence="53 54">
        <name type="scientific">Thrush coronavirus HKU12 (isolate Grey-backed thrush/Hong Kong/HKU12-600/2007)</name>
        <name type="common">ThCoV-HKU12</name>
        <name type="synonym">Thrush coronavirus HKU12-600</name>
        <dbReference type="NCBI Taxonomy" id="572290"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Pisuviricota</taxon>
            <taxon>Pisoniviricetes</taxon>
            <taxon>Nidovirales</taxon>
            <taxon>Cornidovirineae</taxon>
            <taxon>Coronaviridae</taxon>
            <taxon>Orthocoronavirinae</taxon>
            <taxon>Deltacoronavirus</taxon>
            <taxon>Buldecovirus</taxon>
            <taxon>unclassified Buldecovirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Turdus merula</name>
        <name type="common">Common blackbird</name>
        <dbReference type="NCBI Taxonomy" id="9187"/>
    </organismHost>
    <organismHost>
        <name type="scientific">Turdus hortulorum</name>
        <dbReference type="NCBI Taxonomy" id="411519"/>
    </organismHost>
    <reference evidence="53 54" key="1">
        <citation type="journal article" date="2009" name="J. Virol." volume="83" first="908" last="917">
            <title>Comparative analysis of complete genome sequences of three avian coronaviruses reveals a novel group 3c coronavirus.</title>
            <authorList>
                <person name="Woo P.C."/>
                <person name="Lau S.K."/>
                <person name="Lam C.S."/>
                <person name="Lai K.K."/>
                <person name="Huang Y."/>
                <person name="Lee P."/>
                <person name="Luk G.S."/>
                <person name="Dyrting K.C."/>
                <person name="Chan K.H."/>
                <person name="Yuen K.Y."/>
            </authorList>
            <dbReference type="PubMed" id="18971277"/>
            <dbReference type="DOI" id="10.1128/JVI.01977-08"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="54">Isolate Grey-backed thrush/Hong Kong/HKU12-600/2007</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="39">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:67020"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="Rhea" id="RHEA-COMP:17168"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167609"/>
            <dbReference type="EC" id="2.1.1.57"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="40">
            <text>uridylyl-uridylyl-ribonucleotide-RNA = a 3'-end uridylyl-2',3'-cyclophospho-uridine-RNA + a 5'-end dephospho-ribonucleoside-RNA</text>
            <dbReference type="Rhea" id="RHEA:67732"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17334"/>
            <dbReference type="Rhea" id="RHEA-COMP:17335"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173079"/>
            <dbReference type="ChEBI" id="CHEBI:173080"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum-Golgi intermediate compartment</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Host cytoplasm</location>
            <location evidence="7">Host perinuclear region</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Host endoplasmic reticulum-Golgi intermediate compartment</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the coronaviruses polyprotein 1ab family.</text>
    </comment>
    <dbReference type="EMBL" id="FJ376621">
        <property type="protein sequence ID" value="ACJ12052.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002308496.1">
        <property type="nucleotide sequence ID" value="NC_011549.1"/>
    </dbReference>
    <dbReference type="GeneID" id="7040223"/>
    <dbReference type="KEGG" id="vg:7040223"/>
    <dbReference type="Proteomes" id="UP000011786">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044172">
        <property type="term" value="C:host cell endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033644">
        <property type="term" value="C:host cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044220">
        <property type="term" value="C:host cell perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004532">
        <property type="term" value="F:exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008242">
        <property type="term" value="F:omega peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039520">
        <property type="term" value="P:induction by virus of host autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019082">
        <property type="term" value="P:viral protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039694">
        <property type="term" value="P:viral RNA genome replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21409">
        <property type="entry name" value="1B_cv_Nsp13-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20762">
        <property type="entry name" value="capping_2-OMTase_Nidovirales"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21512">
        <property type="entry name" value="cv_gamma-delta_Nsp2_IBV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21473">
        <property type="entry name" value="cv_Nsp4_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21561">
        <property type="entry name" value="deltaCoV-Nsp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21657">
        <property type="entry name" value="deltaCoV_Nsp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21668">
        <property type="entry name" value="deltaCoV_Nsp5_Mpro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21590">
        <property type="entry name" value="deltaCoV_RdRp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21169">
        <property type="entry name" value="M_dcv_Nsp15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21557">
        <property type="entry name" value="Macro_X_Nsp3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21161">
        <property type="entry name" value="NendoU_cv_Nsp15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21172">
        <property type="entry name" value="NTD_dcv_Nsp15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21401">
        <property type="entry name" value="ZBD_cv_Nsp13-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027351">
        <property type="entry name" value="(+)RNA_virus_helicase_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043608">
        <property type="entry name" value="CoV_NSP15_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043606">
        <property type="entry name" value="CoV_NSP15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043611">
        <property type="entry name" value="CoV_NSP3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032505">
        <property type="entry name" value="CoV_NSP4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043612">
        <property type="entry name" value="CoV_NSP4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037227">
        <property type="entry name" value="EndoU-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044371">
        <property type="entry name" value="Macro_X_NSP3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043609">
        <property type="entry name" value="NendoU_nidovirus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044863">
        <property type="entry name" value="NIRAN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036333">
        <property type="entry name" value="NSP10_sf_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044343">
        <property type="entry name" value="NSP13_1B_dom_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027352">
        <property type="entry name" value="NSP13_ZBD_CoV-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009466">
        <property type="entry name" value="NSP14_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044317">
        <property type="entry name" value="NSP14_deltaCoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044324">
        <property type="entry name" value="NSP15_M_deltaCoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043174">
        <property type="entry name" value="NSP15_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042515">
        <property type="entry name" value="NSP15_N_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044331">
        <property type="entry name" value="NSP15_N_deltaCoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044401">
        <property type="entry name" value="NSP15_NendoU_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009461">
        <property type="entry name" value="NSP16_CoV-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044383">
        <property type="entry name" value="NSP2_IBV-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038123">
        <property type="entry name" value="NSP4_C_sf_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044307">
        <property type="entry name" value="NSP5_Mpro_deltaCoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043610">
        <property type="entry name" value="NSP6_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044365">
        <property type="entry name" value="NSP6_deltaCoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037204">
        <property type="entry name" value="NSP7_sf_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014829">
        <property type="entry name" value="NSP8_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037230">
        <property type="entry name" value="NSP8_sf_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014822">
        <property type="entry name" value="NSP9_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036499">
        <property type="entry name" value="NSP9_sf_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013016">
        <property type="entry name" value="Peptidase_C16_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008740">
        <property type="entry name" value="Peptidase_C30_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043477">
        <property type="entry name" value="Peptidase_C30_dom3_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043178">
        <property type="entry name" value="PLpro_thumb_sf_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044354">
        <property type="entry name" value="RdRp_deltaCoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001205">
        <property type="entry name" value="RNA-dir_pol_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007094">
        <property type="entry name" value="RNA-dir_pol_PSvirus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009469">
        <property type="entry name" value="RNA_pol_N_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018995">
        <property type="entry name" value="RNA_synth_NSP10_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06471">
        <property type="entry name" value="CoV_ExoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06460">
        <property type="entry name" value="CoV_Methyltr_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09401">
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<entry dataset="TrEMBL" created="2008-12-16" modified="2022-01-19" version="44" xmlns="http://uniprot.org/uniprot">
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            <title>Comparative analysis of complete genome sequences of three avian coronaviruses reveals a novel group 3c coronavirus.</title>
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                <person name="Lau S.K."/>
                <person name="Lam C.S."/>
                <person name="Lai K.K."/>
                <person name="Huang Y."/>
                <person name="Lee P."/>
                <person name="Luk G.S."/>
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    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019031">
        <property type="term" value="C:viral envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055036">
        <property type="term" value="C:virion membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0075509">
        <property type="term" value="P:endocytosis involved in viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039654">
        <property type="term" value="P:fusion of virus membrane with host endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019064">
        <property type="term" value="P:fusion of virus membrane with host plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046813">
        <property type="term" value="P:receptor-mediated virion attachment to host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043607">
        <property type="entry name" value="CoV_S1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043473">
        <property type="entry name" value="S2_sf_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002551">
        <property type="entry name" value="Spike_S1_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002552">
        <property type="entry name" value="Spike_S2_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043614">
        <property type="entry name" value="Spike_S2_CoV_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044873">
        <property type="entry name" value="Spike_S2_CoV_HR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044874">
        <property type="entry name" value="Spike_S2_CoV_HR2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01600">
        <property type="entry name" value="CoV_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19209">
        <property type="entry name" value="CoV_S1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01601">
        <property type="entry name" value="CoV_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19214">
        <property type="entry name" value="CoV_S2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111474">
        <property type="entry name" value="SSF111474"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51923">
        <property type="entry name" value="COV_S2_HR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51924">
        <property type="entry name" value="COV_S2_HR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-1043">Host membrane</keyword>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-1161">Viral attachment to host cell</keyword>
    <keyword evidence="7" id="KW-0261">Viral envelope protein</keyword>
    <keyword evidence="5" id="KW-0946">Virion</keyword>
    <keyword evidence="9" id="KW-0843">Virulence</keyword>
    <keyword evidence="13" id="KW-1160">Virus entry into host cell</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1132"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="domain" description="COV_S2_HR1" evidence="16">
        <location>
            <begin position="785"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="domain" description="COV_S2_HR2" evidence="17">
        <location>
            <begin position="1048"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="911"/>
            <end position="938"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ACJ12053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000011786"/>
        </source>
    </evidence>
    <sequence length="1192" mass="133036" checksum="6EC26E056C265F23" modified="2008-12-16" version="1">MQRVILICFITLASAARLVDRVFDALTFPNAHQYLRDTRQIQPRWLPSAEEPKSDGKGHFTQNVHRFAFLTNGSSPVDQIIRTTQPLLLRCPQWFGYNGSGNWVLKFNFSESNYCNDGYNYNGNKVVSHIRLIGAFLASPSVDYVFTLQTTSGSTYYLNCSTSQRPVGFDAEMQRNYCYVKTANYTQFIGILPERVADVTFSREGTFYVNGFGMGSFGQLARITVDKGALATFNHSWAYFVDEADVLLNITDSQIQGIVYCDKDLYDHLRCQQSSFSLTDGFYSTAKYTTNQQRKTIFVTLPKHTYTETISILPNISNPAYPDGSTNGPALGWWVGTMNVLFNNSQTLCVNSSFFMVNITFKCWLKPHPTKPSDEYKCIGGLPTAQVKLPDWPFAPYYSFSQLCLSSTYQVGYSTFYFQYWNQGTNKRWESKPLFYYTYQTGTQYTYVTKPVISFTDVSELSLYECVDYNIYGVIGSGIIQPSNISYLNGLYYTSSAGQLLAFKNSTTFQIYTVQPCDSPGQVIVYNNSFIGAITASNQTILNFKSRIATPTFYYHTNATSVQGNCNTAPLQFSSIGICPDGSIMQVNTTVDTLPATTIITSGNITIPLNFTISIQAEYLQIQAQHTVVDCQTYVCNGNAKCLQLLQQYSTACSNIEQSLTMSARLDNAETLAMVQTSTQGYHLSKIEQHDNQYNLTAILPNKQGGRSAIEDLLFDKVVTNGLGTVDQDYKECTKGVSLADLACAQYYSGIMVLPGVVDAEKMAMYTASLTGGMFFGGLTAASSIPFSVAVQARLNYVALQTDVLQKNQQILANSFNQAMGNITLAFSSVNDALQQTSEVIQTVANALNKIQDVVNKQGSALNHLTLQLQNNFDAISHSIADIYARLDEVEANQQVDRLITGRLAALNAYVTQVLTQISQLKAQRQLAQEKINECVKSQSDRFGFCGNGSHLFSITQAAPNGILFLHTVLTPTDRVQVNAIAGICVSDSAFVLREPNLAFFQHDGKWLISPRRLFQPRPATVADFVQIQSCEVTFYNTTYDELPQLIPDYVDVNQTVSDILANKTDPSLDLKLDIYNQTVLNLSAEVDELFQRAQNLTLIFKQLEQYINNINNTLVDLEWLNRVETYIKWPWWVWLLIVLAIAAFACIVITIFLCTGCCGGCFGCCGGCFGLFSKRKFDSDPTPVSFKLKEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-12-16" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>B6VDX9</accession>
    <name>B6VDX9_THCOV</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Small membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">E</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Thrush coronavirus HKU12 (isolate Grey-backed thrush/Hong Kong/HKU12-600/2007)</name>
        <name type="common">ThCoV-HKU12</name>
        <name type="synonym">Thrush coronavirus HKU12-600</name>
        <dbReference type="NCBI Taxonomy" id="572290"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Pisuviricota</taxon>
            <taxon>Pisoniviricetes</taxon>
            <taxon>Nidovirales</taxon>
            <taxon>Cornidovirineae</taxon>
            <taxon>Coronaviridae</taxon>
            <taxon>Orthocoronavirinae</taxon>
            <taxon>Deltacoronavirus</taxon>
            <taxon>Buldecovirus</taxon>
            <taxon>unclassified Buldecovirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Turdus merula</name>
        <name type="common">Common blackbird</name>
        <dbReference type="NCBI Taxonomy" id="9187"/>
    </organismHost>
    <organismHost>
        <name type="scientific">Turdus hortulorum</name>
        <dbReference type="NCBI Taxonomy" id="411519"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="J. Virol." volume="83" first="908" last="917">
            <title>Comparative analysis of complete genome sequences of three avian coronaviruses reveals a novel group 3c coronavirus.</title>
            <authorList>
                <person name="Woo P.C."/>
                <person name="Lau S.K."/>
                <person name="Lam C.S."/>
                <person name="Lai K.K."/>
                <person name="Huang Y."/>
                <person name="Lee P."/>
                <person name="Luk G.S."/>
                <person name="Dyrting K.C."/>
                <person name="Chan K.H."/>
                <person name="Yuen K.Y."/>
            </authorList>
            <dbReference type="PubMed" id="18971277"/>
            <dbReference type="DOI" id="10.1128/JVI.01977-08"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Isolate Grey-backed thrush/Hong Kong/HKU12-600/2007</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="FJ376621">
        <property type="protein sequence ID" value="ACJ12054.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002308498.1">
        <property type="nucleotide sequence ID" value="NC_011549.1"/>
    </dbReference>
    <dbReference type="SMR" id="B6VDX9"/>
    <dbReference type="GeneID" id="7040216"/>
    <dbReference type="KEGG" id="vg:7040216"/>
    <dbReference type="Proteomes" id="UP000011786">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACJ12054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000011786"/>
        </source>
    </evidence>
    <sequence length="82" mass="9397" checksum="670FDE6231CE6284" modified="2008-12-16" version="1">MVVEDWSITIPGQYVIAALVILIVCVTLLFINTCLACVKLSYKCFLGARYLVNPIIVYYSKPNPTPEEEFVKIHQFPRNNYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-12-16" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>B6VDY0</accession>
    <name>B6VDY0_THCOV</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Membrane protein</fullName>
            <shortName evidence="1">M protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">E1 glycoprotein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Matrix glycoprotein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Membrane glycoprotein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">M</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Thrush coronavirus HKU12 (isolate Grey-backed thrush/Hong Kong/HKU12-600/2007)</name>
        <name type="common">ThCoV-HKU12</name>
        <name type="synonym">Thrush coronavirus HKU12-600</name>
        <dbReference type="NCBI Taxonomy" id="572290"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Pisuviricota</taxon>
            <taxon>Pisoniviricetes</taxon>
            <taxon>Nidovirales</taxon>
            <taxon>Cornidovirineae</taxon>
            <taxon>Coronaviridae</taxon>
            <taxon>Orthocoronavirinae</taxon>
            <taxon>Deltacoronavirus</taxon>
            <taxon>Buldecovirus</taxon>
            <taxon>unclassified Buldecovirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Turdus merula</name>
        <name type="common">Common blackbird</name>
        <dbReference type="NCBI Taxonomy" id="9187"/>
    </organismHost>
    <organismHost>
        <name type="scientific">Turdus hortulorum</name>
        <dbReference type="NCBI Taxonomy" id="411519"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="J. Virol." volume="83" first="908" last="917">
            <title>Comparative analysis of complete genome sequences of three avian coronaviruses reveals a novel group 3c coronavirus.</title>
            <authorList>
                <person name="Woo P.C."/>
                <person name="Lau S.K."/>
                <person name="Lam C.S."/>
                <person name="Lai K.K."/>
                <person name="Huang Y."/>
                <person name="Lee P."/>
                <person name="Luk G.S."/>
                <person name="Dyrting K.C."/>
                <person name="Chan K.H."/>
                <person name="Yuen K.Y."/>
            </authorList>
            <dbReference type="PubMed" id="18971277"/>
            <dbReference type="DOI" id="10.1128/JVI.01977-08"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Isolate Grey-backed thrush/Hong Kong/HKU12-600/2007</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Virion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FJ376621">
        <property type="protein sequence ID" value="ACJ12055.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002308499.1">
        <property type="nucleotide sequence ID" value="NC_011549.1"/>
    </dbReference>
    <dbReference type="GeneID" id="7040217"/>
    <dbReference type="KEGG" id="vg:7040217"/>
    <dbReference type="Proteomes" id="UP000011786">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044178">
        <property type="term" value="C:host cell Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019031">
        <property type="term" value="C:viral envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055036">
        <property type="term" value="C:virion membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039660">
        <property type="term" value="F:structural constituent of virion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21594">
        <property type="entry name" value="deltaCoV_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002574">
        <property type="entry name" value="M_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044346">
        <property type="entry name" value="M_deltaCoV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01635">
        <property type="entry name" value="CoV_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51927">
        <property type="entry name" value="COV_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1040">Host Golgi apparatus</keyword>
    <keyword evidence="1" id="KW-1043">Host membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0261">Viral envelope protein</keyword>
    <keyword evidence="1" id="KW-0468">Viral matrix protein</keyword>
    <keyword evidence="1" id="KW-0946">Virion</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACJ12055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000011786"/>
        </source>
    </evidence>
    <sequence length="217" mass="24362" checksum="2D1324112E0AB32D" modified="2008-12-16" version="1">MSDAQEWQVIVFIIIIWALGVILQGGYATRARLIYIIKLILLWLLQPFTLVVTIWSAVDNGNNKTGAVFIISIIFAVLTFLSWLRYWYDSIRLVIKTHSAWSFSPESRLLAGINDPMGNWRCIPIDHMAPILAPVVKHGKLKLHGQELASGVTVSSVPKSMIVVSPSDTFHYTLKKTIDTDERDFAVLIYQGDRVSNAGLHSITTSDSGNARLYKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-12-16" modified="2021-04-07" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>B6VDY1</accession>
    <name>B6VDY1_THCOV</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nonstructural protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">NS6</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Thrush coronavirus HKU12 (isolate Grey-backed thrush/Hong Kong/HKU12-600/2007)</name>
        <name type="common">ThCoV-HKU12</name>
        <name type="synonym">Thrush coronavirus HKU12-600</name>
        <dbReference type="NCBI Taxonomy" id="572290"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Pisuviricota</taxon>
            <taxon>Pisoniviricetes</taxon>
            <taxon>Nidovirales</taxon>
            <taxon>Cornidovirineae</taxon>
            <taxon>Coronaviridae</taxon>
            <taxon>Orthocoronavirinae</taxon>
            <taxon>Deltacoronavirus</taxon>
            <taxon>Buldecovirus</taxon>
            <taxon>unclassified Buldecovirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Turdus merula</name>
        <name type="common">Common blackbird</name>
        <dbReference type="NCBI Taxonomy" id="9187"/>
    </organismHost>
    <organismHost>
        <name type="scientific">Turdus hortulorum</name>
        <dbReference type="NCBI Taxonomy" id="411519"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="J. Virol." volume="83" first="908" last="917">
            <title>Comparative analysis of complete genome sequences of three avian coronaviruses reveals a novel group 3c coronavirus.</title>
            <authorList>
                <person name="Woo P.C."/>
                <person name="Lau S.K."/>
                <person name="Lam C.S."/>
                <person name="Lai K.K."/>
                <person name="Huang Y."/>
                <person name="Lee P."/>
                <person name="Luk G.S."/>
                <person name="Dyrting K.C."/>
                <person name="Chan K.H."/>
                <person name="Yuen K.Y."/>
            </authorList>
            <dbReference type="PubMed" id="18971277"/>
            <dbReference type="DOI" id="10.1128/JVI.01977-08"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">Isolate Grey-backed thrush/Hong Kong/HKU12-600/2007</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="FJ376621">
        <property type="protein sequence ID" value="ACJ12056.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002308500.1">
        <property type="nucleotide sequence ID" value="NC_011549.1"/>
    </dbReference>
    <dbReference type="GeneID" id="7040218"/>
    <dbReference type="KEGG" id="vg:7040218"/>
    <dbReference type="Proteomes" id="UP000011786">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="CDD" id="cd21629">
        <property type="entry name" value="NS6_deltaCoV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044335">
        <property type="entry name" value="NS6_deltaCoV"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACJ12056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000011786"/>
        </source>
    </evidence>
    <sequence length="91" mass="10305" checksum="F460C07D0375139D" modified="2008-12-16" version="1">MCNCLYQVKALVEYSKTHGKTDVLELLDPLVKTRCFAYTLVVCINANPVAFSILPRKLLINGEPLLIEYGNVYGKDFIIRPSLQVILEEEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-12-16" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>B6VDY2</accession>
    <name>B6VDY2_THCOV</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Nucleocapsid phosphoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">N</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Thrush coronavirus HKU12 (isolate Grey-backed thrush/Hong Kong/HKU12-600/2007)</name>
        <name type="common">ThCoV-HKU12</name>
        <name type="synonym">Thrush coronavirus HKU12-600</name>
        <dbReference type="NCBI Taxonomy" id="572290"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Pisuviricota</taxon>
            <taxon>Pisoniviricetes</taxon>
            <taxon>Nidovirales</taxon>
            <taxon>Cornidovirineae</taxon>
            <taxon>Coronaviridae</taxon>
            <taxon>Orthocoronavirinae</taxon>
            <taxon>Deltacoronavirus</taxon>
            <taxon>Buldecovirus</taxon>
            <taxon>unclassified Buldecovirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Turdus merula</name>
        <name type="common">Common blackbird</name>
        <dbReference type="NCBI Taxonomy" id="9187"/>
    </organismHost>
    <organismHost>
        <name type="scientific">Turdus hortulorum</name>
        <dbReference type="NCBI Taxonomy" id="411519"/>
    </organismHost>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2009" name="J. Virol." volume="83" first="908" last="917">
            <title>Comparative analysis of complete genome sequences of three avian coronaviruses reveals a novel group 3c coronavirus.</title>
            <authorList>
                <person name="Woo P.C."/>
                <person name="Lau S.K."/>
                <person name="Lam C.S."/>
                <person name="Lai K.K."/>
                <person name="Huang Y."/>
                <person name="Lee P."/>
                <person name="Luk G.S."/>
                <person name="Dyrting K.C."/>
                <person name="Chan K.H."/>
                <person name="Yuen K.Y."/>
            </authorList>
            <dbReference type="PubMed" id="18971277"/>
            <dbReference type="DOI" id="10.1128/JVI.01977-08"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">Isolate Grey-backed thrush/Hong Kong/HKU12-600/2007</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="FJ376621">
        <property type="protein sequence ID" value="ACJ12057.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002308501.1">
        <property type="nucleotide sequence ID" value="NC_011549.1"/>
    </dbReference>
    <dbReference type="GeneID" id="7040219"/>
    <dbReference type="KEGG" id="vg:7040219"/>
    <dbReference type="Proteomes" id="UP000011786">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019013">
        <property type="term" value="C:viral nucleocapsid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21595">
        <property type="entry name" value="CoV_N-CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21554">
        <property type="entry name" value="CoV_N-NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044344">
        <property type="entry name" value="N_prot_C_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044345">
        <property type="entry name" value="N_prot_N_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001218">
        <property type="entry name" value="Nucleocap_CoV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037179">
        <property type="entry name" value="Nucleocapsid_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037195">
        <property type="entry name" value="Nucleocapsid_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00937">
        <property type="entry name" value="CoV_nucleocap"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103068">
        <property type="entry name" value="SSF103068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110304">
        <property type="entry name" value="SSF110304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51929">
        <property type="entry name" value="COV_N_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51928">
        <property type="entry name" value="COV_N_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0013">ADP-ribosylation</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 9 13" id="KW-0543">Viral nucleoprotein</keyword>
    <keyword evidence="3 9" id="KW-0946">Virion</keyword>
    <feature type="domain" description="CoV N NTD" evidence="11">
        <location>
            <begin position="9"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="CoV N CTD" evidence="12">
        <location>
            <begin position="177"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="133"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="286"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="292"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ACJ12057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000011786"/>
        </source>
    </evidence>
    <sequence length="343" mass="38028" checksum="651CBB23F269A80C" modified="2008-12-16" version="1">MSAPVVPTTDASWFQVLKAQNKKAIHPQFRGDGVPLNSAIKPQENHGYWLRYNRQKPGGAAIPPSYAFYYTGTGPRGNLKFGEYPPNDSKDTSRITWVKAKGADTSIKPHVAKRNPNNPKHALLPLRFPSGDGPAAGFRVDPFNTRGRQLERAPGPRSMSMDTRPAANQPRKRDQSAPAAVRRKTQHQAPKRTLQKGKTISQVFGHRSRTGANVGSADTEKSGMADPRIMALARYVPGVQEMLFAGHVDSQFQVNDITLTFTYSITVKENSPDYIRIKDALSTVVNQTYEPPTKPKKEKKPVEQASKNNQQKKKPAKQETAKPDNSADLEWDDAFEIKQDSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-12-16" modified="2020-10-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>B6VDY3</accession>
    <name>B6VDY3_THCOV</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nonstructural protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">NS7a</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Thrush coronavirus HKU12 (isolate Grey-backed thrush/Hong Kong/HKU12-600/2007)</name>
        <name type="common">ThCoV-HKU12</name>
        <name type="synonym">Thrush coronavirus HKU12-600</name>
        <dbReference type="NCBI Taxonomy" id="572290"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Pisuviricota</taxon>
            <taxon>Pisoniviricetes</taxon>
            <taxon>Nidovirales</taxon>
            <taxon>Cornidovirineae</taxon>
            <taxon>Coronaviridae</taxon>
            <taxon>Orthocoronavirinae</taxon>
            <taxon>Deltacoronavirus</taxon>
            <taxon>Buldecovirus</taxon>
            <taxon>unclassified Buldecovirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Turdus merula</name>
        <name type="common">Common blackbird</name>
        <dbReference type="NCBI Taxonomy" id="9187"/>
    </organismHost>
    <organismHost>
        <name type="scientific">Turdus hortulorum</name>
        <dbReference type="NCBI Taxonomy" id="411519"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2009" name="J. Virol." volume="83" first="908" last="917">
            <title>Comparative analysis of complete genome sequences of three avian coronaviruses reveals a novel group 3c coronavirus.</title>
            <authorList>
                <person name="Woo P.C."/>
                <person name="Lau S.K."/>
                <person name="Lam C.S."/>
                <person name="Lai K.K."/>
                <person name="Huang Y."/>
                <person name="Lee P."/>
                <person name="Luk G.S."/>
                <person name="Dyrting K.C."/>
                <person name="Chan K.H."/>
                <person name="Yuen K.Y."/>
            </authorList>
            <dbReference type="PubMed" id="18971277"/>
            <dbReference type="DOI" id="10.1128/JVI.01977-08"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">Isolate Grey-backed thrush/Hong Kong/HKU12-600/2007</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="FJ376621">
        <property type="protein sequence ID" value="ACJ12058.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002308502.1">
        <property type="nucleotide sequence ID" value="NC_011549.1"/>
    </dbReference>
    <dbReference type="GeneID" id="7040220"/>
    <dbReference type="KEGG" id="vg:7040220"/>
    <dbReference type="Proteomes" id="UP000011786">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ACJ12058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000011786"/>
        </source>
    </evidence>
    <sequence length="123" mass="14089" checksum="49F29DA7A58255FB" modified="2008-12-16" version="1">MAEKRTKLTYPLGGSHETYVPSSCCNSIEPCYISTMHPYQPYISESFKLILEEIAECGNTQSPHAFLYYQEPGLKIWKIHWQRGTDCGPGHCITVFQNKEKGSVNWEEQDFTSHSVFTIPLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-12-16" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>B6VDY4</accession>
    <name>B6VDY4_THCOV</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nonstructural protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NS7b</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Thrush coronavirus HKU12 (isolate Grey-backed thrush/Hong Kong/HKU12-600/2007)</name>
        <name type="common">ThCoV-HKU12</name>
        <name type="synonym">Thrush coronavirus HKU12-600</name>
        <dbReference type="NCBI Taxonomy" id="572290"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Pisuviricota</taxon>
            <taxon>Pisoniviricetes</taxon>
            <taxon>Nidovirales</taxon>
            <taxon>Cornidovirineae</taxon>
            <taxon>Coronaviridae</taxon>
            <taxon>Orthocoronavirinae</taxon>
            <taxon>Deltacoronavirus</taxon>
            <taxon>Buldecovirus</taxon>
            <taxon>unclassified Buldecovirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Turdus merula</name>
        <name type="common">Common blackbird</name>
        <dbReference type="NCBI Taxonomy" id="9187"/>
    </organismHost>
    <organismHost>
        <name type="scientific">Turdus hortulorum</name>
        <dbReference type="NCBI Taxonomy" id="411519"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="J. Virol." volume="83" first="908" last="917">
            <title>Comparative analysis of complete genome sequences of three avian coronaviruses reveals a novel group 3c coronavirus.</title>
            <authorList>
                <person name="Woo P.C."/>
                <person name="Lau S.K."/>
                <person name="Lam C.S."/>
                <person name="Lai K.K."/>
                <person name="Huang Y."/>
                <person name="Lee P."/>
                <person name="Luk G.S."/>
                <person name="Dyrting K.C."/>
                <person name="Chan K.H."/>
                <person name="Yuen K.Y."/>
            </authorList>
            <dbReference type="PubMed" id="18971277"/>
            <dbReference type="DOI" id="10.1128/JVI.01977-08"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Isolate Grey-backed thrush/Hong Kong/HKU12-600/2007</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="FJ376621">
        <property type="protein sequence ID" value="ACJ12059.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002308503.1">
        <property type="nucleotide sequence ID" value="NC_011549.1"/>
    </dbReference>
    <dbReference type="GeneID" id="7040221"/>
    <dbReference type="KEGG" id="vg:7040221"/>
    <dbReference type="Proteomes" id="UP000011786">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACJ12059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000011786"/>
        </source>
    </evidence>
    <sequence length="83" mass="9124" checksum="C62CFF46AE66F0BA" modified="2008-12-16" version="1">MGTSQSSVSVNNQITNIHASEHSSVQTSNSNTSEIQALLQQGLPYLVILLSILLLLQSAFIIHLLRRVRRLKSRLFAAAPLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2008-12-16" modified="2020-10-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>B6VDY5</accession>
    <name>B6VDY5_THCOV</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nonstructural protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NS7c</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Thrush coronavirus HKU12 (isolate Grey-backed thrush/Hong Kong/HKU12-600/2007)</name>
        <name type="common">ThCoV-HKU12</name>
        <name type="synonym">Thrush coronavirus HKU12-600</name>
        <dbReference type="NCBI Taxonomy" id="572290"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Pisuviricota</taxon>
            <taxon>Pisoniviricetes</taxon>
            <taxon>Nidovirales</taxon>
            <taxon>Cornidovirineae</taxon>
            <taxon>Coronaviridae</taxon>
            <taxon>Orthocoronavirinae</taxon>
            <taxon>Deltacoronavirus</taxon>
            <taxon>Buldecovirus</taxon>
            <taxon>unclassified Buldecovirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Turdus merula</name>
        <name type="common">Common blackbird</name>
        <dbReference type="NCBI Taxonomy" id="9187"/>
    </organismHost>
    <organismHost>
        <name type="scientific">Turdus hortulorum</name>
        <dbReference type="NCBI Taxonomy" id="411519"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2009" name="J. Virol." volume="83" first="908" last="917">
            <title>Comparative analysis of complete genome sequences of three avian coronaviruses reveals a novel group 3c coronavirus.</title>
            <authorList>
                <person name="Woo P.C."/>
                <person name="Lau S.K."/>
                <person name="Lam C.S."/>
                <person name="Lai K.K."/>
                <person name="Huang Y."/>
                <person name="Lee P."/>
                <person name="Luk G.S."/>
                <person name="Dyrting K.C."/>
                <person name="Chan K.H."/>
                <person name="Yuen K.Y."/>
            </authorList>
            <dbReference type="PubMed" id="18971277"/>
            <dbReference type="DOI" id="10.1128/JVI.01977-08"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">Isolate Grey-backed thrush/Hong Kong/HKU12-600/2007</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="FJ376621">
        <property type="protein sequence ID" value="ACJ12060.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002308504.1">
        <property type="nucleotide sequence ID" value="NC_011549.1"/>
    </dbReference>
    <dbReference type="GeneID" id="7040222"/>
    <dbReference type="KEGG" id="vg:7040222"/>
    <dbReference type="Proteomes" id="UP000011786">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACJ12060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000011786"/>
        </source>
    </evidence>
    <sequence length="77" mass="9108" checksum="2B066279323A5DA7" modified="2008-12-16" version="1">MFETLYYAELLGPLIDIEVLGFVTFIHYFWHYRPRRCQHVIPQESQSEGAIMQTRAGYSCTESHLDKCQCKKDTYTI</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>