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<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-12-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>O72899</accession>
    <name>I2_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein I2 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Protein FPV089</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV089</name>
        <name type="ORF">FPI2L</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1998" name="Virus Genes" volume="17" first="5" last="9">
            <title>Nucleotide sequence of the 4.3 kbp BamHI-N fragment of fowlpox virus FP9.</title>
            <authorList>
                <person name="Pollitt E."/>
                <person name="Skinner M.A."/>
                <person name="Heaphy S."/>
            </authorList>
            <dbReference type="PubMed" id="9778782"/>
            <dbReference type="DOI" id="10.1023/A:1008045914991"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Late protein which probably plays a role in virus entry into the host cell.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Virion membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
        <text>Component of the membrane of the mature virion.</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the chordopoxvirinae I2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AJ223385">
        <property type="protein sequence ID" value="CAA11292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039052.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486637"/>
    <dbReference type="KEGG" id="vg:1486637"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009175">
        <property type="entry name" value="Poxvirus_I2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12575">
        <property type="entry name" value="Pox_EPC_I2-L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003766">
        <property type="entry name" value="VAC_I2L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <keyword id="KW-1160">Virus entry into host cell</keyword>
    <feature type="chain" id="PRO_0000099570" description="Protein I2 homolog">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="65" mass="7573" checksum="ECDD9A25B824DF92" modified="1998-08-01" version="1">MEKLFTGTYGVFLESNDSDFEDFINTIMTVLTGKKESKQLSWLTIFIIFVVCIVVFTFLYLKLMC</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>O72902</accession>
    <name>I6_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Telomere-binding protein I6 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Protein FPV084</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV084</name>
        <name type="ORF">FPI6L</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="submission" date="1998-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Pollitt E."/>
                <person name="Skinner M.A."/>
                <person name="Heaphy S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to the hairpin form of the viral telomeric sequence. Might direct genome encapsidation into the virus particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Present in the virus core.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae I6 family.</text>
    </comment>
    <dbReference type="EMBL" id="AJ223385">
        <property type="protein sequence ID" value="CAA11297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="E48563">
        <property type="entry name" value="E48563"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039047.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486632"/>
    <dbReference type="KEGG" id="vg:1486632"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007674">
        <property type="entry name" value="Poxvirus_36kDa_major_membrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022219">
        <property type="entry name" value="Poxvirus_I6_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12562">
        <property type="entry name" value="DUF3746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04595">
        <property type="entry name" value="Pox_I6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099581" description="Telomere-binding protein I6 homolog">
        <location>
            <begin position="1"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="390" mass="45297" checksum="522A8FCA369DD14A" modified="1998-08-01" version="1">MDNFLKQISSNVKKPIAELEDPDAVIKFHYMNISFNFPDLYYCNNNLFDKPENNLLDISKSLLMLNSFSHECFILQDILRVIRRYGHVYDVYFLPIGWLVGHGEAPKYHASIKLIRSNTQEIIDGIIRRQLSQYGIQGDNLSIFVDSSNEVAINRHSIIGARQLNPICVVSFYPFDPEHKVFFVIYVGRYKDKYCGISYVADREDMYKVINRIYPYVSCFYLVSDGIINFHTTPVANHTRNIKPLPVNYCNTLCEIVYDFEYLKFEQGVMSIPVFMPFVPKQFVSIINLPDDILITCTASSNIEYITHIDNKKLKRILIIIKDKFLKGTIMQGTFKKVNIIRHKKYTYTITYSSFDCPKLEDTKSSLPSTCNKAILDGRRYVTKTFNDTI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>O72903</accession>
    <name>I7_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Core protease I7 homolog</fullName>
            <ecNumber>3.4.22.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Protein FPV083</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV083</name>
        <name type="ORF">FPI7L</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="submission" date="1998-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Pollitt E."/>
                <person name="Skinner M.A."/>
                <person name="Heaphy S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Late protein responsible for processing most or all of the viral core and membrane proteins known to undergo morphogenesis-associated proteolysis. These proteolytic events are involved in the transformation of immature virions (IV) into mature virions (MV).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Present in the virion core.</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C57 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-"/>
    <dbReference type="EMBL" id="AJ223385">
        <property type="protein sequence ID" value="CAA11298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="F48563">
        <property type="entry name" value="F48563"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039046.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="MEROPS" id="C57.001"/>
    <dbReference type="GeneID" id="1486631"/>
    <dbReference type="KEGG" id="vg:1486631"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004970">
        <property type="entry name" value="Peptidase_C57"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03290">
        <property type="entry name" value="Peptidase_C57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0788">Thiol protease</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099585" description="Core protease I7 homolog">
        <location>
            <begin position="1"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="421" mass="48621" checksum="B58813864F2F10BA" modified="1998-08-01" version="1">MDKYTELVINKIPELGFVNLLSHIYQTVGLCSSIDISKFKTNCNGYVVERFDKSETAGKVSCVPISILMELVERGMLSKPDNSKSQLEVKTDLVNELISKNNGFEDIMTIPTSIPMKYFFKPVLKEKVSKAIDFSVMDIKGDDVSRMGIRYGENDKVVKIKIAPERDAWMTNTSIHQFLIPMCYGTEVIYIGQFNFNFMNRHAIYEKSSVFNKNTEVFKLKDRIRDNRSSRFIMFGFCYLHHWKCAIYDKNRDFICFYDSGGNNPNEFNHYRNFFFYSNSDGLNRNSYLSSLANENADIDILFNFFIDNYGVTAGCINVEVNQLLESECGMFTCLFMAVCCLNPPKGFKGIRKIYTYFKFLADKKVTMLKSILFNVGKMEFTIKEVDGEGMQQYKKMEKWCANTINILANKITSRVEDIIN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-08-12" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>O72910</accession>
    <name>VLTF2_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Viral late gene transcription factor 2</fullName>
            <shortName>VLTF-2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName>Trans-activator protein A1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">VLTF2</name>
        <name type="ordered locus">FPV049</name>
        <name type="ORF">FP-A1</name>
        <name type="ORF">FPA1</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="submission" date="1998-05" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Skinner M.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1990" name="J. Gen. Virol." volume="71" first="2873" last="2881">
            <title>Analysis of the fowlpox virus genome region corresponding to the vaccinia virus D6 to A1 region: location of, and variation in, non-essential genes in poxviruses.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Britton B.S."/>
                <person name="Mason C."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2177083"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Acts with RNA polymerase to initiate transcription from late gene promoters.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with itself. Interacts with the late transcription factors VLTF-1.</text>
    </comment>
    <comment type="developmental stage">
        <text>Intermediate stages of infection.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae VLTF-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AJ005163">
        <property type="protein sequence ID" value="CAA06404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S42254">
        <property type="entry name" value="S42254"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039012.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486597"/>
    <dbReference type="KEGG" id="vg:1486597"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004975">
        <property type="entry name" value="Poxvirus_VLTF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010507">
        <property type="entry name" value="Znf_MYM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03295">
        <property type="entry name" value="Pox_TAA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06467">
        <property type="entry name" value="zf-FCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0010">Activator</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <feature type="chain" id="PRO_0000099174" description="Viral late gene transcription factor 2">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="154" mass="17983" checksum="6BE3AE570F844167" modified="1998-08-01" version="1">MYKKVNLSGIVISEPKSVKKFKTKDSIVNVLPEYYHTIADKRLEIRKDKDNCWFCKQDMNTYNPYFIETLYGDHIGVFCSKICRDSFANMIKSVIALREEPKISLLPLELYEKPEEVLEVINDLRHKEGIYGSCILESDKNIIKLTLRCHCNTN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2019-10-16" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>P0DTA5</accession>
    <accession>O72909</accession>
    <accession>Q70HA0</accession>
    <accession>Q9J5F4</accession>
    <name>D13_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Scaffold protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>62 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>D13 ortholog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>N3L protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>Rifampicin resistance protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV050</name>
        <name type="ordered locus">fp9.050</name>
        <name type="ORF">FP-D13</name>
        <name type="ORF">FPD13</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Scaffold protein which forms a transitory spherical honeycomb lattice providing curvature and rigidity to the convex membrane of crescent and immature virions (IV). This association occurs concomitantly with viral membrane formation. Targeted by the drug rifampicin, which prevents the formation of this lattice, and hence virus morphogenesis. In the presence of rifampicin, irregularly shaped membranes that lack the honeycomb layer accumulate around areas of electron-dense viroplasm. This layer is lost from virions during maturation from IV to mature virion (MV), through the proteolysis of A17 N-terminus.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotrimer (By similarity). Self-assembles to form a layer. Interacts with A17 (via N-terminus); this interaction is necessary for D13 association with membranes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location>Membrane</location>
            <topology>Peripheral membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">Associates transitorily with crescent and IV membranes.</text>
    </comment>
    <comment type="miscellaneous">
        <text>Displays structure similarities to capsid proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviridae protein D13 family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous gene model prediction">
            <sequence resource="EMBL-CDS" id="AAF44394" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44394.1"/>
        <property type="status" value="ALT_SEQ"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S42253">
        <property type="entry name" value="S42253"/>
    </dbReference>
    <dbReference type="SMR" id="P0DTA5"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005008">
        <property type="entry name" value="Poxvirus_Rif-R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03340">
        <property type="entry name" value="Pox_Rif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099129" description="Scaffold protein">
        <location>
            <begin position="1"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="552" mass="62413" checksum="899E55999D02A245" modified="2019-10-16" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="1989-07-01" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>P10052</accession>
    <name>KITH_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Thymidine kinase</fullName>
            <ecNumber>2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">TK</name>
        <name type="ordered locus">FPV086</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1987" name="Virology" volume="156" first="355" last="365">
            <title>Fowlpox virus thymidine kinase: nucleotide sequence and relationships to other thymidine kinases.</title>
            <authorList>
                <person name="Boyle D.B."/>
                <person name="Coupar B.E.H."/>
                <person name="Gibbs A.J."/>
                <person name="Seigman L.J."/>
                <person name="Both G.W."/>
            </authorList>
            <dbReference type="PubMed" id="3027984"/>
            <dbReference type="DOI" id="10.1016/0042-6822(87)90415-6"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1275" last="1283">
            <title>Comparison of a conserved region in fowlpox virus and vaccinia virus genomes and the translocation of the fowlpox virus thymidine kinase gene.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Tomley F.M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2838574"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="1992" name="Virus Res." volume="24" first="161" last="172">
            <title>Gene translocations in poxviruses: the fowlpox virus thymidine kinase gene is flanked by 15 bp direct repeats and occupies the locus which in vaccinia virus is occupied by the ribonucleotide reductase large subunit gene.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Boursnell M.E.G."/>
                <person name="Skinner M.A."/>
            </authorList>
            <dbReference type="PubMed" id="1326827"/>
            <dbReference type="DOI" id="10.1016/0168-1702(92)90004-S"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="4">
        <citation type="submission" date="1990-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Beisel C.E."/>
                <person name="Nazerian K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>Vaccine</strain>
        </source>
    </reference>
    <reference key="5">
        <citation type="submission" date="2001-07" db="EMBL/GenBank/DDBJ databases">
            <title>Sequence of thymidine kinase gene of Indian isolate of fowlpox virus.</title>
            <authorList>
                <person name="Senthilvelan A."/>
                <person name="Purushothaman V."/>
                <person name="Palaniswami K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="6">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction>
            <text>ATP + thymidine = ADP + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the thymidine kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21"/>
    <dbReference type="EMBL" id="M16617">
        <property type="protein sequence ID" value="AAA43822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="D00321">
        <property type="protein sequence ID" value="BAA00233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AJ223385">
        <property type="protein sequence ID" value="CAA11295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="X52860">
        <property type="protein sequence ID" value="CAA37041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF396867">
        <property type="protein sequence ID" value="AAK77606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="A27532">
        <property type="entry name" value="KIVZFP"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039049.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P10052"/>
    <dbReference type="GeneID" id="1486634"/>
    <dbReference type="KEGG" id="vg:1486634"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020633">
        <property type="entry name" value="Thymidine_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="PTHR11441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00603">
        <property type="entry name" value="TK_CELLULAR_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0237">DNA synthesis</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000174930" description="Thymidine kinase">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="11"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="163"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="183" mass="20381" checksum="FA60C5629F2DF276" modified="1989-07-01" version="1">MSSGSIHVITGPMFSGKTSELVRRIKRFMLSNFKCIIIKHCGDNRYNEDDINKVYTHDLLFMEATASSNLSVLVPTLLNDGVQVIGIDEAQFFLDIVEFSESMANLGKTVIVAALNGDFKRELFGNVYKLLSLAETVSSLTAICVKCYCDASFSKRVTENKEVMDIGGKDKYIAVCRKCFFSN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-01-01" modified="2020-12-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>P14361</accession>
    <accession>Q9ICB1</accession>
    <name>V006_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein FPV006/FPV255</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>BamHI-ORF1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV006</name>
    </gene>
    <gene>
        <name type="ordered locus">FPV255</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1025" last="1040">
            <title>Sequence analysis of an 11.2 kilobase, near-terminal, BamHI fragment of fowlpox virus.</title>
            <authorList>
                <person name="Tomley F."/>
                <person name="Binns M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E."/>
            </authorList>
            <dbReference type="PubMed" id="2836548"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the poxviruses C4/C10 family.</text>
    </comment>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="A29963">
        <property type="entry name" value="WMVZFV"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038969.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039218.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486827"/>
    <dbReference type="GeneID" id="1486838"/>
    <dbReference type="KEGG" id="vg:1486827"/>
    <dbReference type="KEGG" id="vg:1486838"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005004">
        <property type="entry name" value="Poxvirus_C4/C10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03336">
        <property type="entry name" value="Pox_C4_C10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003698">
        <property type="entry name" value="VAC_C10L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0244">Early protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099724" description="Uncharacterized protein FPV006/FPV255">
        <location>
            <begin position="1"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; BAA00190." evidence="1" ref="1">
        <original>S</original>
        <variation>G</variation>
        <location>
            <position position="4"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; BAA00190." evidence="1" ref="1">
        <original>E</original>
        <variation>Q</variation>
        <location>
            <position position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="418" mass="48326" checksum="FCF1F27A492AD131" modified="2001-08-29" version="2">MEFSCTGTNNQLAVHRFTETRFTSFKKELLVNLGISDLNDIKNICEDSKIFFPEKRTELLSIKDRKSKQIVFENSLNDDLLKKLHALIYDELSTVVDSVTVENTVTLIMYEKGDYFARHRDFSTVFSKNIICVHLLLYLEQPETGGETVIYIDNNTSVKLKTDHLFDKTIEHESITVESGRKCVALFDVLLEKKLSASTNVIGSIEYLGKKINLYDRENDLQLCYCDMVIERMTEDKEYSLGMISDRSGRCIKSHHNGSIVRYRKEEYGSFDALCIYNMNEVDEIWTGDKKHIIWSTIDKKTGTSFIPIDPVLYEKLKAISSKEHKEYKDLRGFCNSRTEYICCSVSKYYFDLPTKTDLIHEVINSIDYDTKSVGTPDWYTLPIEVKQTILGNMSYEELFNIVRGNIALEEDNEYGCD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-01-01" modified="2020-08-12" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>P14364</accession>
    <name>V248_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein FPV248</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>BamHI-ORF6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV248</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1025" last="1040">
            <title>Sequence analysis of an 11.2 kilobase, near-terminal, BamHI fragment of fowlpox virus.</title>
            <authorList>
                <person name="Tomley F."/>
                <person name="Binns M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E."/>
            </authorList>
            <dbReference type="PubMed" id="2836548"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="F29963">
        <property type="entry name" value="WMVZF6"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039211.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486820"/>
    <dbReference type="KEGG" id="vg:1486820"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017880">
        <property type="entry name" value="KilA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA_N/APSES_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51301">
        <property type="entry name" value="KILA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0244">Early protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099735" description="Uncharacterized protein FPV248">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="KilA-N" evidence="1">
        <location>
            <begin position="11"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00631"/>
        </source>
    </evidence>
    <sequence length="151" mass="17967" checksum="0F6E850144CD5B76" modified="1990-01-01" version="1">MEIKVESINNNFCKLSYEDIEIIMMKENEYINATRLCSSRGRDILDWMSKESSVELINELDRINRSCNDYYDYRGIVLNVVSDSETSELYVHRDLILHISHWISPLFSLKVVKFINSYIQDSYQLEYELIHKKSLMDQLKEIILLNDDNNM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-01-01" modified="2022-02-23" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>P14366</accession>
    <name>V237_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein FPV237</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>BamHI-ORF9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV237</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1025" last="1040">
            <title>Sequence analysis of an 11.2 kilobase, near-terminal, BamHI fragment of fowlpox virus.</title>
            <authorList>
                <person name="Tomley F."/>
                <person name="Binns M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E."/>
            </authorList>
            <dbReference type="PubMed" id="2836548"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="I29963">
        <property type="entry name" value="WMVZF9"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039200.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486809"/>
    <dbReference type="KEGG" id="vg:1486809"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0244">Early protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099733" description="Uncharacterized protein FPV237">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <sequence length="67" mass="7928" checksum="F4502AA087EAB307" modified="1990-01-01" version="1">MSSLKYANTDITIKMVIITPKVLEDDSLSESSIHFANNRFHFDLYYIKPWAFVSILYLFLCFLYNII</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-01-01" modified="2022-02-23" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>P14368</accession>
    <accession>P14367</accession>
    <accession>Q9J501</accession>
    <name>V234_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV234</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>BamHI-ORF12/ORF13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV234</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1025" last="1040">
            <title>Sequence analysis of an 11.2 kilobase, near-terminal, BamHI fragment of fowlpox virus.</title>
            <authorList>
                <person name="Tomley F."/>
                <person name="Binns M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E."/>
            </authorList>
            <dbReference type="PubMed" id="2836548"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 65-428</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <comment type="sequence caution" evidence="1">
        <conflict type="frameshift">
            <sequence resource="EMBL-CDS" id="BAA00207" version="1"/>
        </conflict>
    </comment>
    <comment type="sequence caution" evidence="1">
        <conflict type="frameshift">
            <sequence resource="EMBL-CDS" id="BAA00209" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00209.1"/>
        <property type="status" value="ALT_FRAME"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00207.1"/>
        <property type="status" value="ALT_FRAME"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="C30087">
        <property type="entry name" value="WMVZTW"/>
    </dbReference>
    <dbReference type="PIR" id="D30087">
        <property type="entry name" value="WMVZTH"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039197.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P14368"/>
    <dbReference type="GeneID" id="1486806"/>
    <dbReference type="KEGG" id="vg:1486806"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018272">
        <property type="entry name" value="PRANC_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09372">
        <property type="entry name" value="PRANC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067125" description="Putative ankyrin repeat protein FPV234">
        <location>
            <begin position="1"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="39"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="71"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="103"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="137"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 6">
        <location>
            <begin position="174"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 7">
        <location>
            <begin position="206"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 8">
        <location>
            <begin position="242"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="428" mass="49194" checksum="C71BEAF74687EE8F" modified="2001-08-29" version="2">MQVRNKDDILICEAIENYDSESLRNILENGADPNVRVPYQYSHLHNAIEKKNGSAVSLLLKHGADPNISGFFTPPLHKAIKKGCVDIARSLLEYGAIVNLEHYCLKPIHIAANRTESKIVKLLIEYGADINSEDGANGKYPIHYAMKVYDPFRLKIIKVLLDHGADINKQSVLTNTSPLYETRFITDDLLDYIISRGANINIKGRMGRNILHEIILRNGYNDFSNILVLIDHGADINALDDEGNTPFMLHTINNNAIILANYIVSLYYLSYKARISNGMEKNMKIINKCEYLSSCINIIKEEIERMKTFKIYDGNSFQDLSLFDLLSNEDNIAIVYRLSDTLLEKMNIIKTIFPNCFRIIQNILKMLTKRYEMLLEINNIMNANLVNTKWYTLPIEIRWMILTKLDDMILRNLLLQNETNNIKNCKKQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-01-01" modified="2020-08-12" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>P14369</accession>
    <accession>Q9J4Z2</accession>
    <name>V251_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized serpin-like protein FPV251</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV251</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1025" last="1040">
            <title>Sequence analysis of an 11.2 kilobase, near-terminal, BamHI fragment of fowlpox virus.</title>
            <authorList>
                <person name="Tomley F."/>
                <person name="Binns M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E."/>
            </authorList>
            <dbReference type="PubMed" id="2836548"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the serpin family. Poxviruses subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="C29963">
        <property type="entry name" value="WMVZF3"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039214.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P14369"/>
    <dbReference type="GeneID" id="1486823"/>
    <dbReference type="KEGG" id="vg:1486823"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="PTHR11461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="SSF56574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0646">Protease inhibitor</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="chain" id="PRO_0000094158" description="Uncharacterized serpin-like protein FPV251">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; BAA00194." evidence="1" ref="1">
        <original>S</original>
        <variation>L</variation>
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="148" mass="16438" checksum="60428E34E286994A" modified="2001-08-29" version="2">MLKLICLRNFNTFSILGVVDSLNNGKNINKIISKKDMTLKEIVLYLPKFELEDDVDLKDALIHMGCNDLFKSGELVGISDTKTLRIGNIRQKSVIKVDEYGTEAASVTESCTTDGIKKIPIVKANVPFMFLVADVQTKIPLFLGIFQG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-01-01" modified="2020-08-12" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>P14371</accession>
    <accession>Q9J500</accession>
    <name>V239_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative C-type lectin protein FPV239</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>BamHI-ORF8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV239</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1025" last="1040">
            <title>Sequence analysis of an 11.2 kilobase, near-terminal, BamHI fragment of fowlpox virus.</title>
            <authorList>
                <person name="Tomley F."/>
                <person name="Binns M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E."/>
            </authorList>
            <dbReference type="PubMed" id="2836548"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-116</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="H29963">
        <property type="entry name" value="WMVZF8"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039201.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P14371"/>
    <dbReference type="PRIDE" id="P14371"/>
    <dbReference type="GeneID" id="1486811"/>
    <dbReference type="KEGG" id="vg:1486811"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="CDD" id="cd03593">
        <property type="entry name" value="CLECT_NK_receptors_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033992">
        <property type="entry name" value="NKR-like_CTLD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0430">Lectin</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000046729" description="Putative C-type lectin protein FPV239">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="1">
        <location>
            <begin position="48"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="76"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="137"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00040"/>
        </source>
    </evidence>
    <sequence length="163" mass="18635" checksum="5156DC8928855532" modified="2001-08-29" version="2">MEEGKPRRSSAVLWMLIPCGSIIIVLSVFVIILSTRPPVPPDIKILYCKEGWVGYNKNCYFFSEEKNNKSLAVERCKDMDGHLTSISSKEEFKFILRYKGPGNHWIGIEKVDFNGTWKLEDGSSYDNIVPIKGIGDCAYLSDRSIMSSFCFLPKKWICRIILL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-04-01" modified="2020-12-02" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>P15910</accession>
    <accession>Q9J595</accession>
    <name>L1_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein L1 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Virion membrane protein M25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV128</name>
        <name type="ORF">FP2</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1275" last="1283">
            <title>Comparison of a conserved region in fowlpox virus and vaccinia virus genomes and the translocation of the fowlpox virus thymidine kinase gene.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Tomley F.M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2838574"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-444</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Envelope protein which probably plays a role in virus entry into the host cell. Is probably involved in the virus attachment to the host cell surface and associates with the entry/fusion complex (EFC). Needed for fusion and penetration of the virus core into host cell.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with G4; this interaction involves formation of a transient disulfide-bonded intermediate, allowing disulfide bond transfer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Virion membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">Localizes to the membrane surrounding the core of mature virus particles (MV).</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Myristoylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the chordopoxvirinae L1 family.</text>
    </comment>
    <dbReference type="EMBL" id="D00320">
        <property type="protein sequence ID" value="BAA00225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="JS0222">
        <property type="entry name" value="WMVZP2"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039091.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P15910"/>
    <dbReference type="GeneID" id="1486676"/>
    <dbReference type="KEGG" id="vg:1486676"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003472">
        <property type="entry name" value="Virion_mem_poxvirus_L1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02442">
        <property type="entry name" value="L1R_F9L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0945">Host-virus interaction</keyword>
    <keyword id="KW-0449">Lipoprotein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0519">Myristate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-1161">Viral attachment to host cell</keyword>
    <keyword id="KW-0261">Viral envelope protein</keyword>
    <keyword id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <keyword id="KW-1160">Virus entry into host cell</keyword>
    <feature type="initiator methionine" description="Removed; by host" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000099615" description="Protein L1 homolog">
        <location>
            <begin position="2"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="topological domain" description="Virion surface" evidence="2">
        <location>
            <begin position="2"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="topological domain" description="Intravirion" evidence="2">
        <location>
            <begin position="205"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Targeting to MV membrane" evidence="1">
        <location>
            <begin position="2"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="N-myristoyl glycine; by host" evidence="1">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="49"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="116"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; BAA00225." evidence="3" ref="1">
        <original>S</original>
        <variation>C</variation>
        <location>
            <position position="19"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; BAA00225." evidence="3" ref="1">
        <original>A</original>
        <variation>R</variation>
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="243" mass="26519" checksum="36B7CD3E8E3284B8" modified="2007-01-23" version="4">MGAAASIQTTVTTINKKISEKLEQTASASATANCDINIGNIIFKKNKGCNVLVKNMCSANASAQLDAIVSAVREVYDQLTEQQKAYAPSLLTAALNIQTNVSTITQDFETYIKQKCNSDAVINNIINVQSLEVDECSAPPGQIMTFEFINTGTATGNCAMKSVLDVLTKSSDRVSGNQSTGNDFSKYLYIIGGIICFLILLYYAKKLFFMSTNDKVKVLLAKKPDVHWTTYIDTYFRSSPVLV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-04-01" modified="2020-08-12" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>P15912</accession>
    <name>V130_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein FPV130</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV130</name>
        <name type="ORF">FP4</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1275" last="1283">
            <title>Comparison of a conserved region in fowlpox virus and vaccinia virus genomes and the translocation of the fowlpox virus thymidine kinase gene.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Tomley F.M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2838574"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-444</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the poxviruses L3 family.</text>
    </comment>
    <dbReference type="EMBL" id="D00320">
        <property type="protein sequence ID" value="BAA00227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="JS0224">
        <property type="entry name" value="WMVZP4"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039093.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486678"/>
    <dbReference type="KEGG" id="vg:1486678"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005007">
        <property type="entry name" value="Poxvirus_L3/FP4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03339">
        <property type="entry name" value="Pox_L3_FP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099624" description="Protein FPV130">
        <location>
            <begin position="1"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="301" mass="35368" checksum="4828F0EB751F73DC" modified="1990-04-01" version="1">MSKNNATTESNRQIPFTEQRLCDYYQERKRYEISCYIGEYFNIRKQVCIDEANYWVTLSALVKAGKALGFPLVYSVKDHTYGRTIYFEYFKNMKRTNLNINTVCLTKDIILQIVAILYSLYKNNIFSDDFKFDLVSIPRSTISMSINHLVLLFNTESLILLSTNTHLYKSELSQSCYLDYMTAHQDLMTRRNLKSTNYFFEWFIRNHFENISRQYLDIFKIKKNYINTPQIHRLTEPGSLVYVMYNDALIMGITLSDVSLNNIVRVIYSIDGGNIFEIDDFSTNDVFTAKELITRSTNINL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-04-01" modified="2020-12-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>P15913</accession>
    <name>VP8_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Core protein VP8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>25 kDa major core protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>L4 core protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>P25K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV131</name>
        <name type="ORF">FP5</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1275" last="1283">
            <title>Comparison of a conserved region in fowlpox virus and vaccinia virus genomes and the translocation of the fowlpox virus thymidine kinase gene.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Tomley F.M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2838574"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-444</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Major core structural protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Localizes to the virion core.</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Undergoes morphogenesis-associated proteolysis which cleaves the 28 kDa to a 25-kDa product. Proteolytic cleavage of major core proteins P4a (A10L), P4b (A3L), and VP8 (L4R), which occurs at a late stage of core formation, is required for production of infectious mature virions (MV).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae VP8 family.</text>
    </comment>
    <dbReference type="EMBL" id="D00320">
        <property type="protein sequence ID" value="BAA00228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="JS0225">
        <property type="entry name" value="WMVZP5"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039094.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486679"/>
    <dbReference type="KEGG" id="vg:1486679"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007586">
        <property type="entry name" value="VP8_pox_nuc-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04498">
        <property type="entry name" value="Pox_VP8_L4R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="propeptide" id="PRO_0000040595" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000040596" description="Core protein VP8">
        <location>
            <begin position="32"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by core protease I7" evidence="1">
        <location>
            <begin position="31"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="253" mass="28345" checksum="E8E68B0360E6002D" modified="1990-04-01" version="1" precursor="true">MNDLLLENLFGEKALCAQVTRDQLLEIIAAGARSKFPKSLLSMYRVTPRVMTRYPLKLITNESITGVVITTVYNLKKNLNIPQNNKLTTQDIERYYLDKSVEVINLMVGNTSLGDLACGRPRRTKSSKKKDPVIFLGISAPLILVMNSKKSINTYIQDKKSDPSSDYVNINPGIGVLENYGNTYLLDIHNPSSVLTISTIYGLDNNMELKKLSTASEIDAYQDVNIGKSVDLKKFNEIFNTMKKHLSLSNFSI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-04-01" modified="2022-08-03" version="109" xmlns="http://uniprot.org/uniprot">
    <accession>P15916</accession>
    <accession>Q85279</accession>
    <accession>Q9J594</accession>
    <name>MCE_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase</fullName>
            <ecNumber>2.1.1.57</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Poly(A) polymerase regulatory subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>Poly(A) polymerase small subunit</fullName>
            <shortName>PAP-S</shortName>
        </alternativeName>
        <alternativeName>
            <fullName>VP39</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">PAPS</name>
        <name type="ordered locus">FPV134</name>
        <name type="ORF">FP9</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1987" name="Virology" volume="160" first="203" last="209">
            <title>Similar genetic organization between a region of fowlpox virus DNA and the vaccinia virus HindIII J fragment despite divergent location of the thymidine kinase gene.</title>
            <authorList>
                <person name="Drillien R."/>
                <person name="Spehner D."/>
                <person name="Villeval D."/>
                <person name="Lecocq J.-P."/>
            </authorList>
            <dbReference type="PubMed" id="2820129"/>
            <dbReference type="DOI" id="10.1016/0042-6822(87)90061-4"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>Salisbury</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1275" last="1283">
            <title>Comparison of a conserved region in fowlpox virus and vaccinia virus genomes and the translocation of the fowlpox virus thymidine kinase gene.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Tomley F.M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2838574"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-206</scope>
        <source>
            <strain>FP-9 / Isolate HP-444</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Displays methyltransferase, positive regulation of the poly(A) polymerase and transcription elongation activities. Involved in the modification of both mRNA ends and in intermediate and late gene positive transcription elongation. At the mRNAs 5' end, methylates the ribose 2' OH group of the first transcribed nucleotide, thereby producing a 2'-O-methylpurine cap. At the 3' end, functions as a processivity factor which stimulates the activity of the viral poly(A) polymerase VP55 that creates mRNA's poly(A) tail. In the presence of VP39, VP55 does not dissociate from the RNA allowing tail elongation to around 250 adenylates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:67020"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="Rhea" id="RHEA-COMP:17168"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167609"/>
            <dbReference type="EC" id="2.1.1.57"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Methyltransferase activity: Monomer, poly(A) polymerase activity: Heterodimer composed of a catalytic component, VP55, and a processivity factor, VP39. Interacts with Rap94 and NPH-I; these interactions might help linking transcription to capping and polyadenylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Virion</location>
        </subcellularLocation>
        <text evidence="3">Localizes to the virion core.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. Poxvirus/kinetoplastid 2'-O-MTase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.57"/>
    <dbReference type="EMBL" id="M17418">
        <property type="protein sequence ID" value="AAA66422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="D00320">
        <property type="protein sequence ID" value="BAA00231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="PS0044">
        <property type="entry name" value="WMVZP9"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039097.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P15916"/>
    <dbReference type="GeneID" id="1486682"/>
    <dbReference type="KEGG" id="vg:1486682"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004483">
        <property type="term" value="F:mRNA (nucleoside-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031440">
        <property type="term" value="P:regulation of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20756">
        <property type="entry name" value="capping_2-OMTase_Poxviridae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000176">
        <property type="entry name" value="mRNA_MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025804">
        <property type="entry name" value="Pox/kineto_cap_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030375">
        <property type="entry name" value="Poxvir_cap_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01358">
        <property type="entry name" value="PARP_regulatory"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003726">
        <property type="entry name" value="PolA_polym_reg_poxV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51612">
        <property type="entry name" value="SAM_MT_2O_PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0251">Elongation factor</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-0506">mRNA capping</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099115" description="Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase">
        <location>
            <begin position="1"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Binding to NPH-I" evidence="2">
        <location>
            <begin position="177"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="active site" description="For methyltransferase activity" evidence="2">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>mRNA</name>
            <dbReference type="ChEBI" id="CHEBI:33699"/>
        </ligand>
        <ligandPart>
            <name>mRNA cap</name>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="185"/>
            <end position="188"/>
        </location>
        <ligand>
            <name>mRNA</name>
            <dbReference type="ChEBI" id="CHEBI:33699"/>
        </ligand>
        <ligandPart>
            <name>mRNA cap</name>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>mRNA</name>
            <dbReference type="ChEBI" id="CHEBI:33699"/>
        </ligand>
        <ligandPart>
            <name>mRNA cap</name>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="213"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>mRNA</name>
            <dbReference type="ChEBI" id="CHEBI:33699"/>
        </ligand>
        <ligandPart>
            <name>mRNA cap</name>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>mRNA</name>
            <dbReference type="ChEBI" id="CHEBI:33699"/>
        </ligand>
        <ligandPart>
            <name>mRNA cap</name>
        </ligandPart>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; AAA66422." evidence="3" ref="1">
        <original>M</original>
        <variation>R</variation>
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="308" mass="36655" checksum="921B7C5A8E6361FF" modified="2001-08-29" version="2">MHEGHQESFKELEMTKPYMFFNELVGEEDYNKELENSNTKFQGQGQLKLLLGELYFLNTLIKNKTLCSDTVIVYIGSAPGSHINFLYHYMDDLKIDLKWILIDGRDHDRSLESLKNVSIIHRFVDEQYLFKLRNMIRKNHKIVLISDIRSLRGKEPTSEDLLHDYALQNQMVSILKPIASSLKWRCPFPDQWIRDFYIPCGDEFLQPFAPPFSAEMRLLSCYSRAPIRLIRIDKNAAIEYEKKMFYLNTKIRPKIVLDFDYPNQKYDYFYMFYILKDIVLPTYKEFSTYKQKVIFLQEAIFNALNIKP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-08-01" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>P17355</accession>
    <name>P4B_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Major core protein 4b</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Virion core protein 4b</fullName>
            <shortName>p4b</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV167</name>
        <name type="ORF">FP4B</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1989" name="Virology" volume="170" first="288" last="291">
            <title>Analysis of the fowlpoxvirus gene encoding the 4b core polypeptide and demonstration that it possesses efficient promoter sequences.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Boursnell M.E.G."/>
                <person name="Tomley F.M."/>
                <person name="Campbell J."/>
            </authorList>
            <dbReference type="PubMed" id="2541544"/>
            <dbReference type="DOI" id="10.1016/0042-6822(89)90380-2"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-444</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1998" name="J. Virol." volume="72" first="170" last="179">
            <title>The 131-amino-acid repeat region of the essential 39-kilodalton core protein of fowlpox virus FP9, equivalent to vaccinia virus A4L protein, is nonessential and highly immunogenic.</title>
            <authorList>
                <person name="Boulanger D."/>
                <person name="Green P."/>
                <person name="Smith T."/>
                <person name="Czerny C.P."/>
                <person name="Skinner M.A."/>
            </authorList>
            <dbReference type="PubMed" id="9420213"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Major component of the virion core that undergoes proteolytic processing during the immature virion (IV) to mature virion (MV) transition. Essential for the formation of a structurally normal core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Localizes to the virion core wall.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">The precursor is cleaved to a mature protein during virion maturation. Proteolytic cleavage of major core proteins P4a (A10L), P4b (A3L), and VP8 (L4R), which occurs at a late stage of core formation, is required for production of infectious mature virions (MV).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviridae protein P4b family.</text>
    </comment>
    <dbReference type="EMBL" id="M25781">
        <property type="protein sequence ID" value="AAA43817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AJ005164">
        <property type="protein sequence ID" value="CAA06406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="A31474">
        <property type="entry name" value="FOVZFV"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039130.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486715"/>
    <dbReference type="KEGG" id="vg:1486715"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004972">
        <property type="entry name" value="P4B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03292">
        <property type="entry name" value="Pox_P4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="propeptide" id="PRO_0000040587" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000040588" description="Major core protein 4b">
        <location>
            <begin position="62"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="657" mass="75217" checksum="78AD757F652C9734" modified="1990-08-01" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-11-01" modified="2020-08-12" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>P18521</accession>
    <name>I5L_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein I5 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV085</name>
        <name type="ORF">FPI5L</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1275" last="1283">
            <title>Comparison of a conserved region in fowlpox virus and vaccinia virus genomes and the translocation of the fowlpox virus thymidine kinase gene.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Tomley F.M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2838574"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-444</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1992" name="Virus Res." volume="24" first="161" last="172">
            <title>Gene translocations in poxviruses: the fowlpox virus thymidine kinase gene is flanked by 15 bp direct repeats and occupies the locus which in vaccinia virus is occupied by the ribonucleotide reductase large subunit gene.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Boursnell M.E.G."/>
                <person name="Skinner M.A."/>
            </authorList>
            <dbReference type="PubMed" id="1326827"/>
            <dbReference type="DOI" id="10.1016/0168-1702(92)90004-S"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion membrane</location>
            <topology>Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">Probably localizes to the membrane of mature virions (MV).</text>
    </comment>
    <comment type="induction">
        <text>Expressed late in the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Chordopoxvirinae I5 family.</text>
    </comment>
    <dbReference type="EMBL" id="D00320">
        <property type="status" value="NOT_ANNOTATED_CDS"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="D00321">
        <property type="protein sequence ID" value="BAA00232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AJ223385">
        <property type="protein sequence ID" value="CAA11296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="JS0228">
        <property type="entry name" value="WMVZ44"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039048.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486633"/>
    <dbReference type="KEGG" id="vg:1486633"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006803">
        <property type="entry name" value="Poxvirus_I5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04713">
        <property type="entry name" value="Pox_I5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003768">
        <property type="entry name" value="VAC_I5L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099730" description="Protein I5 homolog">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="8"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="81" mass="9123" checksum="1E9B4A571CC97B74" modified="1990-11-01" version="1">MEIARETLITIGLTILVVLLIITGFSLVLRLIPGVYSSVSRSSFTAGRILRFMEIFSTIMFIPGIIILYAAYIRKIKMKNN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1991-05-01" modified="2021-09-29" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>P21402</accession>
    <accession>Q9J5C6</accession>
    <name>DPOL_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>DNA polymerase</fullName>
            <ecNumber>2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">POL</name>
        <name type="ordered locus">FPV094</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1987" name="Nucleic Acids Res." volume="15" first="6563" last="6573">
            <title>Identification by a random sequencing strategy of the fowlpoxvirus DNA polymerase gene, its nucleotide sequence and comparison with other viral DNA polymerases.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Stenzler L."/>
                <person name="Tomley F.M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2819823"/>
            <dbReference type="DOI" id="10.1093/nar/15.16.6563"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-444</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes DNA synthesis. Acquires processivity by associating with a heterodimeric processivity factor comprised of the viral A20 and D4 proteins, thereby forming the DNA polymerase holoenzyme. Displays 3'- to 5' exonuclease activity. Might participate in viral DNA recombination. Does not perform translesion synthesis across an abasic site.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with A20. Component of the Uracil-DNA glycosylase(UDG)-A20-polymerase complex; A20 and UDG form a heterodimeric processivity factor that associates with E9 to form the processive polymerase holoenzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7"/>
    <dbReference type="EMBL" id="M31638">
        <property type="protein sequence ID" value="AAA43821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039057.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P21402"/>
    <dbReference type="PRIDE" id="P21402"/>
    <dbReference type="GeneID" id="1486642"/>
    <dbReference type="KEGG" id="vg:1486642"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013617">
        <property type="entry name" value="DNA-dir_DNA_pol_B_vir_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013660">
        <property type="entry name" value="DNApol_B_exo_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08408">
        <property type="entry name" value="DNA_pol_B_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08452">
        <property type="entry name" value="DNAP_B_exo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-1194">Viral DNA replication</keyword>
    <feature type="chain" id="PRO_0000046535" description="DNA polymerase">
        <location>
            <begin position="1"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; AAA43821." evidence="2" ref="1">
        <original>E</original>
        <variation>Q</variation>
        <location>
            <position position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="988" mass="116661" checksum="53A3E0AD4A71A328" modified="2001-08-29" version="2"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="1991-08-01" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>P21966</accession>
    <accession>Q9J5F2</accession>
    <name>ETF1_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Early transcription factor 70 kDa subunit</fullName>
            <ecNumber>3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>ATP-dependent helicase VETFS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>ETF small subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">VETFS</name>
        <name type="ordered locus">FPV057</name>
        <name type="ORF">FPD6</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1990" name="J. Gen. Virol." volume="71" first="1517" last="1524">
            <title>Nucleotide sequence analysis of a 10.5 kbp HindIII fragment of fowlpox virus: relatedness to the central portion of the vaccinia virus HindIII D region.</title>
            <authorList>
                <person name="Tartaglia J."/>
                <person name="Winslow J."/>
                <person name="Goebel S.J."/>
                <person name="Johnson G.P."/>
                <person name="Taylor J."/>
                <person name="Paoletti E."/>
            </authorList>
            <dbReference type="PubMed" id="2165135"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-1</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Acts with RNA polymerase to initiate transcription from early gene promoters. Is recruited by the RPO-associated protein of 94 kDa (RAP94) to form the early transcription complex, which also contains the core RNA polymerase. ETF heterodimer binds to early gene promoters.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of a 70 kDa and a 82 kDa subunit. Part of the early transcription complex composed of ETF, RAP94, and the DNA-directed RNA polymerase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Virion</location>
        </subcellularLocation>
        <text>All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the helicase family. VETF subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-"/>
    <dbReference type="EMBL" id="X17202">
        <property type="protein sequence ID" value="CAA35069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="F35216">
        <property type="entry name" value="F35216"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039020.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P21966"/>
    <dbReference type="GeneID" id="1486605"/>
    <dbReference type="KEGG" id="vg:1486605"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0010">Activator</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0347">Helicase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099073" description="Early transcription factor 70 kDa subunit">
        <location>
            <begin position="1"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="32"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="326"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DEXH box">
        <location>
            <begin position="135"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA35069." evidence="4" ref="1">
        <original>NDIIVVPFNLLFTEYSWMINFRKELNVVV</original>
        <variation>K</variation>
        <location>
            <begin position="605"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="633" mass="73020" checksum="C17DE6EA97EE4D25" modified="2001-08-29" version="2"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="1991-08-01" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>P21969</accession>
    <accession>Q9J5F1</accession>
    <name>D5_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Primase D5</fullName>
            <ecNumber>3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV058</name>
        <name type="ORF">FPD5</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1990" name="J. Gen. Virol." volume="71" first="1517" last="1524">
            <title>Nucleotide sequence analysis of a 10.5 kbp HindIII fragment of fowlpox virus: relatedness to the central portion of the vaccinia virus HindIII D region.</title>
            <authorList>
                <person name="Tartaglia J."/>
                <person name="Winslow J."/>
                <person name="Goebel S.J."/>
                <person name="Johnson G.P."/>
                <person name="Taylor J."/>
                <person name="Paoletti E."/>
            </authorList>
            <dbReference type="PubMed" id="2165135"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-1</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Primase which may have roles in initiation of DNA replication or lagging-strand synthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with A20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the poxviridae D5 family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-"/>
    <dbReference type="EMBL" id="X17202">
        <property type="protein sequence ID" value="CAA35068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="E35216">
        <property type="entry name" value="E35216"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039021.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="PRIDE" id="P21969"/>
    <dbReference type="GeneID" id="1486606"/>
    <dbReference type="KEGG" id="vg:1486606"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004968">
        <property type="entry name" value="DNA_primase/NTPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014015">
        <property type="entry name" value="Helicase_SF3_DNA-vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014818">
        <property type="entry name" value="Phage/plasmid_primase_P4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08706">
        <property type="entry name" value="D5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03288">
        <property type="entry name" value="Pox_D5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51206">
        <property type="entry name" value="SF3_HELICASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0347">Helicase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099442" description="Primase D5">
        <location>
            <begin position="1"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="domain" description="SF3 helicase" evidence="3">
        <location>
            <begin position="479"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Primase" evidence="1">
        <location>
            <begin position="346"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="505"/>
            <end position="512"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA35068." evidence="4" ref="1">
        <original>C</original>
        <variation>Y</variation>
        <location>
            <position position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="791" mass="92595" checksum="349147DB081A4FF1" modified="2001-08-29" version="2"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="1991-08-01" modified="2022-02-23" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>P21971</accession>
    <accession>Q9J5E8</accession>
    <name>V063_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein FPV063</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>FPLeft</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV063</name>
        <name type="ORF">FPleft</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1990" name="J. Gen. Virol." volume="71" first="1517" last="1524">
            <title>Nucleotide sequence analysis of a 10.5 kbp HindIII fragment of fowlpox virus: relatedness to the central portion of the vaccinia virus HindIII D region.</title>
            <authorList>
                <person name="Tartaglia J."/>
                <person name="Winslow J."/>
                <person name="Goebel S.J."/>
                <person name="Johnson G.P."/>
                <person name="Taylor J."/>
                <person name="Paoletti E."/>
            </authorList>
            <dbReference type="PubMed" id="2165135"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 242-400</scope>
        <source>
            <strain>FP-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text>Involved in viral replication.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="X17202">
        <property type="protein sequence ID" value="CAA35063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039026.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="PRIDE" id="P21971"/>
    <dbReference type="GeneID" id="1486611"/>
    <dbReference type="KEGG" id="vg:1486611"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039434">
        <property type="entry name" value="NSs-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11073">
        <property type="entry name" value="NSs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099727" description="Protein FPV063">
        <location>
            <begin position="1"/>
            <end position="400"/>
        </location>
    </feature>
    <sequence length="400" mass="47366" checksum="1A029505C9CC180A" modified="2001-08-29" version="2">MISTYTNILSNNYSLDRFMIDEKNISVNRFRFDRFLSKFGNIINIRMLNGIIVNKYTTISLKLHNSHLLILVLDLPDNIKLKVGIDRLKLFLKRLSARYYMVINSSEHTNHIVITTVKINNNEEEQYKLTLGKKYKILICYYDSNMLRYKSIEQNNKKALLVGCGFIIGKWYIEKKKTRVVKHSISRITKKCITSEYYLDRTNIKVTDISSINAYWICNPIYHYKYKISDILKSKNKSLIQALRWPLGKPSITFFRLWIIGEYGTHNINLDTIVRILKRMTGRKITNNCGLGDILIYAFGIVRKQANKLGLDCKRITFRNFWKEVASIQLIRYNKYKSSMDNKNKQNNKVISPDNNQYKYLPFNPWMLDISKEVELWDDLKLNLLDKNKWYNDWPVLSRA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1994-06-01" modified="2021-09-29" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>P36316</accession>
    <name>F13_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Envelope protein F13 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>43 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>p43K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV108</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1992" name="Virology" volume="191" first="783" last="792">
            <title>Identification and functional analysis of the fowlpox virus homolog of the vaccinia virus p37K major envelope antigen gene.</title>
            <authorList>
                <person name="Calvert J.G."/>
                <person name="Ogawa R."/>
                <person name="Yanagida N."/>
                <person name="Nazerian K."/>
            </authorList>
            <dbReference type="PubMed" id="1333124"/>
            <dbReference type="DOI" id="10.1016/0042-6822(92)90254-M"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Envelope protein associated with the inner side of the enveloped virion (EV) membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Host endoplasmic reticulum membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="1">Component of the inner side of the enveloped virion (EV) membrane. F13 is associated post-translationally with membranes (By similarity).</text>
    </comment>
    <dbReference type="EMBL" id="M88587">
        <property type="protein sequence ID" value="AAA43819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="M88588">
        <property type="protein sequence ID" value="AAA47186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="A44216">
        <property type="entry name" value="A44216"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039071.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P36316"/>
    <dbReference type="GeneID" id="1486656"/>
    <dbReference type="KEGG" id="vg:1486656"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032803">
        <property type="entry name" value="PLDc_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00614">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13918">
        <property type="entry name" value="PLDc_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1038">Host endoplasmic reticulum</keyword>
    <keyword id="KW-1043">Host membrane</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0449">Lipoprotein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0519">Myristate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0261">Viral envelope protein</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="initiator methionine" description="Removed" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000099200" description="Envelope protein F13 homolog">
        <location>
            <begin position="2"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="3">
        <location>
            <begin position="309"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="N-myristoyl glycine; by host" evidence="2">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00153"/>
        </source>
    </evidence>
    <sequence length="377" mass="43022" checksum="5F4666B7C97F9B86" modified="1994-06-01" version="1">MGNIFKPIPKADYQIVETVPQSLTAINSTNLSTYECFKRLIDLAKKEIYIATFCCNLSTNPEGTDILNRLIDVSSKVSVYILVDESSPHKDYEKIKSSHISYIKVDIGVLNNESVGNLLGNFWVVDKLHFYIGSASLMGNALTTIKNMGIYSENNSLAMDLYFRSLDYKIISKKKCLFFTRMATKYHFFKNHNGIFFSDSPEHMVGRKRTFDLDCVIHYIDAAKSTIDLAIVSLLPTKRTKDSIVYWPIIKDALIRAVLERGVKLRVLLGFWKKTDVISKASIKSLNELGVDHIDISTKVFRFPVNSKVDDINNSKMMIIDGRYAHVMTANLDGSHFNHHAFVSFNCMDQQFTKKIAEVFERDWISPYAKEIDMSQI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1994-06-01" modified="2022-02-23" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>P36317</accession>
    <name>F12_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Virion release protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Protein F12 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV109</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1993" name="J. Gen. Virol." volume="74" first="55" last="64">
            <title>Insertional inactivation of a fowlpox virus homologue of the vaccinia virus F12L gene inhibits the release of enveloped virions.</title>
            <authorList>
                <person name="Ogawa R."/>
                <person name="Yanagida N."/>
                <person name="Nazerian K."/>
                <person name="Calvert J.G."/>
            </authorList>
            <dbReference type="PubMed" id="8380837"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Late protein that plays a role in intracellular enveloped virus (IEV) transport to the cell surface on microtubules. When absent, viral morphogenesis halts after the formation of IEV particles, and these are not transported to the cell periphery. Important for plaque formation, extracellular envelope virus (EEV) production and virulence.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Host endosome</location>
        </subcellularLocation>
        <text evidence="1">Associates with the membrane of IEV particles, but not intracellular mature virus (IMV), cell-associated enveloped virus (CEV) or EEV. Colocalizes with microtubules (By similarity).</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Not glycosylated or contains very little carbohydrate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviridae F12 protein family.</text>
    </comment>
    <dbReference type="EMBL" id="M88588">
        <property type="protein sequence ID" value="AAA47187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="M88587">
        <property type="protein sequence ID" value="AAA43820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="JQ1894">
        <property type="entry name" value="JQ1894"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039072.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486657"/>
    <dbReference type="KEGG" id="vg:1486657"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005005">
        <property type="entry name" value="Poxvirus_F12L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008917">
        <property type="entry name" value="TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03337">
        <property type="entry name" value="Pox_F12L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015793">
        <property type="entry name" value="VAC_EEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47454">
        <property type="entry name" value="SSF47454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1039">Host endosome</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <keyword id="KW-0843">Virulence</keyword>
    <feature type="chain" id="PRO_0000099505" description="Virion release protein">
        <location>
            <begin position="1"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="630" mass="74099" checksum="CD8E1F102032020F" modified="1994-06-01" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="1994-06-01" modified="2022-02-23" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>P36700</accession>
    <accession>Q9J5B2</accession>
    <name>F11_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein F11 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV110</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1993" name="J. Gen. Virol." volume="74" first="55" last="64">
            <title>Insertional inactivation of a fowlpox virus homologue of the vaccinia virus F12L gene inhibits the release of enveloped virions.</title>
            <authorList>
                <person name="Ogawa R."/>
                <person name="Yanagida N."/>
                <person name="Nazerian K."/>
                <person name="Calvert J.G."/>
            </authorList>
            <dbReference type="PubMed" id="8380837"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-151</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Stimulates increases in peripheral microtubule dynamics and may increase the motility of the infected cells, contributing to cell-to-cell spread of the virus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the poxviridae F11 protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="M88588">
        <property type="protein sequence ID" value="AAA47188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="PQ0506">
        <property type="entry name" value="PQ0506"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039073.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P36700"/>
    <dbReference type="GeneID" id="1486658"/>
    <dbReference type="KEGG" id="vg:1486658"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007027">
        <property type="entry name" value="Poxvirus_F11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04943">
        <property type="entry name" value="Pox_F11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099501" description="Protein F11 homolog">
        <location>
            <begin position="1"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="451" mass="52010" checksum="664623EA83D3A331" modified="2001-08-29" version="2">MDTNRKRSLDEHDTGEESPGKLQIVEINDEEDITFTDNPYYKLVKSRDNSINLVPLVGCVMIKINDIKGVTDKVNKLLPKTSSKTNSTSCINIPIDSIPLNFLDDGNKYFNVSEVSILQVSHGNDMMNIDKYVDGSFDYIAVLCLKNSGRSVIMLNHCNKQHVMQDNFCLIFRSFYGINILTQIIGESVYLLVKLSPSDLFKIRWSSVIDSNRFMGKKFYIRNLQEDACIEKMKNMEKDIYKNIEFIIINSVLLEDLKSRLDITRELNHTIDKMFNHNNNTLFSDIIKLSEEIIDKDFKNMEKMSDSVLADVKQISKTKNKLRERLLKAAISSKEVEEILSDIPVIEEGTIKQFSLNQRAVYDHYKKVIYKNNSSLDLGCMNIEKSYMFNLYKVYGQNEYMITYILNLINRVKKGMDAIKSNLGDIYKYNIDNINLVVSERINKVISGESL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>Q05569</accession>
    <accession>O93019</accession>
    <name>RP19_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>DNA-directed RNA polymerase 19 kDa subunit</fullName>
            <ecNumber>2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">RPO19</name>
        <name type="ordered locus">FPV169</name>
        <name type="ORF">FP-A5</name>
        <name type="ORF">FPA5</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1990" name="Virus Res." volume="15" first="175" last="186">
            <title>Mapping of a major early/late gene of fowlpox virus.</title>
            <authorList>
                <person name="Kumar S."/>
                <person name="Boyle D.B."/>
            </authorList>
            <dbReference type="PubMed" id="2157318"/>
            <dbReference type="DOI" id="10.1016/0168-1702(90)90007-X"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="1998" name="J. Virol." volume="72" first="170" last="179">
            <title>The 131-amino-acid repeat region of the essential 39-kilodalton core protein of fowlpox virus FP9, equivalent to vaccinia virus A4L protein, is nonessential and highly immunogenic.</title>
            <authorList>
                <person name="Boulanger D."/>
                <person name="Green P."/>
                <person name="Smith T."/>
                <person name="Czerny C.P."/>
                <person name="Skinner M.A."/>
            </authorList>
            <dbReference type="PubMed" id="9420213"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-97</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. DNA-dependent RNA polymerase associates with the early transcription factor (ETF) thereby allowing the early genes transcription. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The DNA-dependent RNA polymerase used for intermediate and late genes expression consists of eight subunits (147) kDa, 133 kDa, 35 kDa, 30 kDa, 22 kDa, 19 kDa, 18 kDa and 7 kDa totalling more than 500 kDa in mass. The same holoenzyme, with the addition of the transcription-specificity factor RAP94, is used for early gene expression.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Virion</location>
        </subcellularLocation>
        <text evidence="1">All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the early phase of the viral replicative cycle. Expression seems to continue throughout virus infection.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the poxviridae DNA-directed RNA polymerase 19 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6"/>
    <dbReference type="EMBL" id="X52461">
        <property type="protein sequence ID" value="CAA36694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AJ005164">
        <property type="protein sequence ID" value="CAA06407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="A60013">
        <property type="entry name" value="A60013"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039132.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q05569"/>
    <dbReference type="GeneID" id="1486717"/>
    <dbReference type="KEGG" id="vg:1486717"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007984">
        <property type="entry name" value="DNA-dir_RNA_Pol_19kDa_poxvir"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05320">
        <property type="entry name" value="Pox_RNA_Pol_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000743">
        <property type="entry name" value="RPO19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0244">Early protein</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099149" description="DNA-directed RNA polymerase 19 kDa subunit">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="167" mass="19500" checksum="D67E10A724179C37" modified="1996-11-01" version="1">MDNSMDINDILLSDDNDYKSYDEDDDSISDIGETSDDCCTTKQSDSRIESFKFDETTQSPHPKQLSERIKAIKQRYTRRISLFEITGILSESYNLLQRGRIPLLNDLTEETFKDSIINIMFKEIEQGNCPIVIQKNGELLSLTDFDKKGVQYHLDYIKTIWRNQRKL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>Q67477</accession>
    <accession>Q9J5F8</accession>
    <name>3BHS_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>3 beta-hydroxysteroid dehydrogenase/Delta 5--&gt;4-isomerase</fullName>
            <shortName>3-beta-HSD</shortName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName>3-beta-hydroxy-Delta(5)-steroid dehydrogenase</fullName>
                <ecNumber>1.1.1.145</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName>3-beta-hydroxy-5-ene steroid dehydrogenase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName>Progesterone reductase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName>Steroid Delta-isomerase</fullName>
                <ecNumber>5.3.3.1</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName>Delta-5-3-ketosteroid isomerase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name type="ordered locus">FPV046</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1994" name="J. Gen. Virol." volume="75" first="2495" last="2498">
            <title>Deletion of fowlpox virus homologues of vaccinia virus genes between the 3 beta-hydroxysteroid dehydrogenase (A44L) and DNA ligase (A50R) genes.</title>
            <authorList>
                <person name="Skinner M.A."/>
                <person name="Moore J.B."/>
                <person name="Binns M.M."/>
                <person name="Smith G.L."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="8077953"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a 3beta-hydroxy-Delta(5)-steroid + NAD(+) = a 3-oxo-Delta(5)-steroid + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:24076"/>
            <dbReference type="ChEBI" id="CHEBI:1722"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:47907"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.145"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a 3-oxo-Delta(5)-steroid = a 3-oxo-Delta(4)-steroid</text>
            <dbReference type="Rhea" id="RHEA:14709"/>
            <dbReference type="ChEBI" id="CHEBI:47907"/>
            <dbReference type="ChEBI" id="CHEBI:47909"/>
            <dbReference type="EC" id="5.3.3.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text>Lipid metabolism; steroid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 3-beta-HSD family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.145"/>
    <dbReference type="EC" id="5.3.3.1"/>
    <dbReference type="EMBL" id="Z29716">
        <property type="protein sequence ID" value="CAA82802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S41971">
        <property type="entry name" value="S41971"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039008.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q67477"/>
    <dbReference type="GeneID" id="1486594"/>
    <dbReference type="KEGG" id="vg:1486594"/>
    <dbReference type="UniPathway" id="UPA00062"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003854">
        <property type="term" value="F:3-beta-hydroxy-delta5-steroid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102294">
        <property type="term" value="F:cholesterol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004769">
        <property type="term" value="F:steroid delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006694">
        <property type="term" value="P:steroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0755">Steroidogenesis</keyword>
    <feature type="chain" id="PRO_0000087797" description="3 beta-hydroxysteroid dehydrogenase/Delta 5--&gt;4-isomerase">
        <location>
            <begin position="1"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA82802." evidence="2" ref="1">
        <original>IRIDQW</original>
        <variation>LDRPM</variation>
        <location>
            <begin position="38"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA82802." evidence="2" ref="1">
        <original>N</original>
        <variation>K</variation>
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="370" mass="42349" checksum="730FE72BA84FA681" modified="2001-08-29" version="2">MRTLVYVVTGGCGFLGRHIINNLILFESSLKEVRVYDIRIDQWLLDLVEKCNIIKIVPVIGDVRNKSTLDEALRSADVVIHIASINDVAGKFTNDSIMDVNINGTKNVVDSCLYNGVRVLVYTSSYSAVGPNFLGDAMIRGNENTYYQSNHKEAYPLSKQLSEKYILEANGTMSNIGLRLCTCALRPLGVFGEYCPVLETLYRRSYKSRKMYKYADDKVFHSRVYAGNVAWMHILAARNMIENGQHSPLCNNVYYCYDTSPTEHYHDFNMHFFNQLGMDLRNTCLPLWCLRFIANINKGLRVLLSPICSYTPLLNPYTLIKECTTFTIETDKAFKDFGYVPLYTWEESRSKTQLWIRELEAKSSSQKPKS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>Q9ICF9</accession>
    <name>V002_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein FPV002/FPV259</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV002</name>
    </gene>
    <gene>
        <name type="ordered locus">FPV259</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="A31685">
        <property type="entry name" value="A31685"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038965.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039222.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486825"/>
    <dbReference type="GeneID" id="1486840"/>
    <dbReference type="KEGG" id="vg:1486825"/>
    <dbReference type="KEGG" id="vg:1486840"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099723" description="Uncharacterized protein FPV002/FPV259">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <sequence length="222" mass="26068" checksum="4A928A80B4AE8454" modified="2000-10-01" version="1">MIVEKIAAWLLYPLCLLRCFLCNSVRPATCKCVHCLLYPFEVCCECMSETLDSLEHSCCYCCVLPLLIIREFWRRVILPTLKATCDCIRLPCVLTRRFCKRTICPLAKSWCRCFCCPCEVFLRCLLFPCMMLRRMHRGRLTGVREPGAFRDSRDPARRGTWVNDWCEDLCVWIWSPCCYVKRCIRTMCDTFTKKIFYWFIAPAGSPRMPEEPSPLSRKVFSS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>Q9ICH6</accession>
    <name>V001_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative C-type lectin protein FPV001/FPV260</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV001</name>
    </gene>
    <gene>
        <name type="ordered locus">FPV260</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038964.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039223.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9ICH6"/>
    <dbReference type="GeneID" id="1486824"/>
    <dbReference type="GeneID" id="1486831"/>
    <dbReference type="KEGG" id="vg:1486824"/>
    <dbReference type="KEGG" id="vg:1486831"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0430">Lectin</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000046724" description="Putative C-type lectin protein FPV001/FPV260">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin">
        <location>
            <begin position="84"/>
            <end position="187"/>
        </location>
    </feature>
    <sequence length="205" mass="23349" checksum="21FD35D180F8C17F" modified="2000-10-01" version="1">MKMNYPIEYYKEKMKFLRDNSERYILPITCLCLTSVVITSCLFAALFVAVRDCKRDSFLEDTTTAITTSSSIATTYRDNLVIHCPRDWISHNGICLLSTGEKVGFRQGIQKCEKLGSDMIGKSEEEMKALKNIWTGNDHSRFWVDNRAAASTFDPVNECAYGTRSSVSEVPKVLTSPCSVRRYLVCKKTDNSYPTTQSSFYNQYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J4Z3</accession>
    <name>Q9J4Z3_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV247 EFc gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV247</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039210.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486819"/>
    <dbReference type="KEGG" id="vg:1486819"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="124" mass="13866" checksum="B4D4903D890A6281" modified="2000-10-01" version="1">MVLDFKVRYIGQESMKSILASALDPLNSQNGRTEDGCFTLQIIKNINFTAPKQLCAVEGDTVKIYFFEGKGGLIFSVKDVMSESSEEESGYVVEGDYVEFEARFTCFITLACTDPKNTIIYCLE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J4Z4</accession>
    <name>V246_FOWPN</name>
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        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV246</fullName>
        </recommendedName>
    </protein>
    <gene>
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    <organism>
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        <name type="common">FPV</name>
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        <name type="common">vertebrates</name>
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    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
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            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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        <property type="entry name" value="PRANC_domain"/>
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</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J4Z5</accession>
    <name>V245_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV245</fullName>
        </recommendedName>
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    <organism>
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            <title>The genome of fowlpox virus.</title>
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                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
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                <person name="Rock D.L."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J4Z9</accession>
    <name>V241_FOWPN</name>
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        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV241</fullName>
        </recommendedName>
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                <person name="Lu Z."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="75" xmlns="http://uniprot.org/uniprot">
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            <fullName>Putative ankyrin repeat protein FPV233</fullName>
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                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
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            <dbReference type="PubMed" id="10729156"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </feature>
    <sequence length="512" mass="59439" checksum="65D8CD0FC0C90086" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J504</accession>
    <name>V231_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV231</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV231</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039194.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J504"/>
    <dbReference type="PRIDE" id="Q9J504"/>
    <dbReference type="GeneID" id="1486803"/>
    <dbReference type="KEGG" id="vg:1486803"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067122" description="Putative ankyrin repeat protein FPV231">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="24"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="57"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <sequence length="256" mass="28913" checksum="E86EA7CFC28DC5BE" modified="2000-10-01" version="1">MFGNTTISKMLLDYGARIDSRNKEECLPLNHAIATNNKELTSLFLARGADTNIVDKYNRSVLHKAIGNNNITSVKLLLNHGIDYNLRDNHGYTALHYAITLQNREITDMLLSSGADPNIMNNEKHTPLYHALLYRSSNVESLILHGADINIVDDTGKTPLSNTYIDIIDNKNIEVIVSQFTILEYIAPDDIKNQLGYKINTDLINNNKRYSTIKQKCVHEINLLKAIKFHSGYSAEIFLIKSKSNIFHNSQGIQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J506</accession>
    <name>Q9J506_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV229</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV229</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039192.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486801"/>
    <dbReference type="KEGG" id="vg:1486801"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="180" mass="21001" checksum="CEAD545B7D3B93DC" modified="2000-10-01" version="1">MGNASSMIHTVNNNPYHKLNSSSDNTLLDVFSVMSDDGKIDMIDAAAVHLLKSWNYELQLFLSSLQDIDMTKRVKDRLVDTTKIVYENRNKEIDEYPVILDGFKNIQDKISIVEKEITDFCNNEIQEDKLEYKANQFKKKGDYRSYLFLKMLAEQDSDISLREKTKSLLKEIISYRKENI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J508</accession>
    <name>V227_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV227</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV227</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039190.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J508"/>
    <dbReference type="GeneID" id="1486799"/>
    <dbReference type="KEGG" id="vg:1486799"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018272">
        <property type="entry name" value="PRANC_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09372">
        <property type="entry name" value="PRANC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067119" description="Putative ankyrin repeat protein FPV227">
        <location>
            <begin position="1"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="58"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="155"/>
            <end position="184"/>
        </location>
    </feature>
    <sequence length="361" mass="42209" checksum="5CD53677E950C4C1" modified="2000-10-01" version="1">MSDNTLLLHTIMILDLEPNYNECRYCVRMLFNAVKFNNIRLVMHLLRNGVDPNFYDEYMRSPIHYAVEKGNTEMVKALLEHKADPNIFDDNFDYPITNSIIENKVEIVKILLQYGADKTMINEFDLLHDAIKNKHIDMAKILIDNGISLTMKDTDDYTPLHYAMLDNDTSVIYNLLDYIFKVKGYDVLGNIVHDILCNYDLYKETTLELLISYYIIISYLYRGIDLSDIYNSNIEILLNSKHLSDIKEKCENEIDVMKNAVICDGIAIIDLCTGYDANSIARNSVNLKRFSDTKLKIYRYYIEPIVEIGKYRRELLYNAINSMNEYCKSESNDIANWSCLPFEIKYKILENIKDDETLRKI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J509</accession>
    <name>V226_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Probable serine/threonine-protein kinase FPV226</fullName>
            <ecNumber>2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV226</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction>
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Poxviruses subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039189.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J509"/>
    <dbReference type="PRIDE" id="Q9J509"/>
    <dbReference type="GeneID" id="1486798"/>
    <dbReference type="KEGG" id="vg:1486798"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000086788" description="Probable serine/threonine-protein kinase FPV226">
        <location>
            <begin position="1"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1 2">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="20"/>
            <end position="28"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10027"/>
        </source>
    </evidence>
    <sequence length="292" mass="33991" checksum="CC0C0AB9632D3B1D" modified="2000-10-01" version="1">MEGIPLIDIYGKQWKIDKLIGCGGFGCVYSTQCASNTRQAVIKVESLNNTTMVSEVLVYNNIYDKNRIALWKNYKNIDHLGIPMYYGCGSFKRNTMYYRFILLERLVENTKELLKRVKKPKPLIKNIMKDMLYTLEYIHEHGISHGDIKPENIMVDGRYRSYLIDYGIVSYFIVNGKHVKYYKESKNWHRGTLYYASLDAHNGTCVTRRGDLESLGYCMLKWAGIPLPWKVFGNNGNMVHVAKCDFIKRVHKNKVNIKSANKGIYDYIKCVTKLSYEEKPDYDLLRQLVNSL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J513</accession>
    <name>V222_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV222</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV222</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039185.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J513"/>
    <dbReference type="GeneID" id="1486794"/>
    <dbReference type="KEGG" id="vg:1486794"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018272">
        <property type="entry name" value="PRANC_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13606">
        <property type="entry name" value="Ank_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09372">
        <property type="entry name" value="PRANC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067116" description="Putative ankyrin repeat protein FPV222">
        <location>
            <begin position="1"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="38"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="103"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="169"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="202"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 6">
        <location>
            <begin position="234"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 7">
        <location>
            <begin position="294"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 8">
        <location>
            <begin position="328"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 9">
        <location>
            <begin position="361"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 10">
        <location>
            <begin position="397"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 11">
        <location>
            <begin position="430"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 12">
        <location>
            <begin position="464"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 13">
        <location>
            <begin position="495"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 14">
        <location>
            <begin position="529"/>
            <end position="559"/>
        </location>
    </feature>
    <sequence length="747" mass="85304" checksum="55F90AF2855C3D28" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J517</accession>
    <name>V218_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV218</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV218</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039181.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J517"/>
    <dbReference type="PRIDE" id="Q9J517"/>
    <dbReference type="GeneID" id="1486790"/>
    <dbReference type="KEGG" id="vg:1486790"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018272">
        <property type="entry name" value="PRANC_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09372">
        <property type="entry name" value="PRANC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067114" description="Putative ankyrin repeat protein FPV218">
        <location>
            <begin position="1"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="120"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 6">
        <location>
            <begin position="153"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 7">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 8">
        <location>
            <begin position="217"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 9">
        <location>
            <begin position="250"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 10">
        <location>
            <begin position="281"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 11">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 12">
        <location>
            <begin position="431"/>
            <end position="460"/>
        </location>
    </feature>
    <sequence length="461" mass="52636" checksum="E5892ABD916AB807" modified="2000-10-01" version="1">MLSLYYAINYKNRKMVERLLREGVHPDSTIKGFYRPLVKSILLRDVDLVSILLQNGANPNNINDETVSPLAIAIKVNSPTIVSLLLDYNADTSLFPLYVSFPIIKVLVYHGIDVNVIDRESRSFLHYAAKNDDVDTVISLILHGANVNVQDSKGLSPLHHAVSKKTTLTAKILLENGARVNIRDSLGRLPLHLGANTYEMVKLLIDYGSPIDIKDVNGSTPLHYAIWKSSLDTIRLLVNVSTINALDNNCNSPLHYIILSETEILVELLLRGADITIKDICGNTPLDILCKLRIKKLDNIKAIISNAFLMREVVPDLLKLCGFESNRKIISNISDLKQHEVSCIKEIHLMKEHSFRKNGPTILDVCTDKVHFLHRLVNARDNVQYKDFPIYCKYIKFRIEKAIYKKTIIEKTILLLDDILIKHEYTSWHDLPYELKHYIIEYINIEFIKSLLEHTNLKNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J525</accession>
    <name>Q9J525_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV210</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV210</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039173.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486782"/>
    <dbReference type="KEGG" id="vg:1486782"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="66" mass="7869" checksum="46078020F9A6B64E" modified="2000-10-01" version="1">MYTLNKSKNTIKEYKMSPSVYIDMLYLKIHLNYNNTTTQSTLKNIQDERTINRSKERIQLNKNING</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J529</accession>
    <name>V206_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>G-protein coupled receptor homolog FPV206</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV206</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Host cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039169.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J529"/>
    <dbReference type="GeneID" id="1486778"/>
    <dbReference type="KEGG" id="vg:1486778"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0297">G-protein coupled receptor</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-1032">Host cell membrane</keyword>
    <keyword id="KW-1043">Host membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0675">Receptor</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0807">Transducer</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000070250" description="G-protein coupled receptor homolog FPV206">
        <location>
            <begin position="1"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="topological domain" description="Extracellular" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=1" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=2" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="topological domain" description="Extracellular" evidence="1">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=3" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=4" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="topological domain" description="Extracellular" evidence="1">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=5" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=6" evidence="1">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="topological domain" description="Extracellular" evidence="1">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=7" evidence="1">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="292"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine; by host" evidence="1">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine; by host" evidence="1">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="89"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="308" mass="35375" checksum="5ABFE53EE1FEB28A" modified="2000-10-01" version="1">MNFTGDCLLYAGYEKLSLSLAVVTILIFSSSLILNISALVIGFYTTAPGPMKMYLINLIVSDILFTVTLPLKIDYYYYFFNWRWGEMACRIMSFLSYINTYVSINFMTWISVNRYYAVTRPHKYNSRDNIMRTKIACACTWVIILVPMSSILFVSTTSSDHETKIRCMEYNKVGDSMYLPPWVTIVMCFIGFVIPFAMMAISYSAVCYTVLSGISKSTRSYRTCKLVACILTEFVICFLPYHASVISYMIHIITSKTVLCENVSYYQMLLHATQCLMKLNCCMDPIIYLFVSSYKSKAKSNSIKLMFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J537</accession>
    <name>Q9J537_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV196</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV196</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039159.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486768"/>
    <dbReference type="KEGG" id="vg:1486768"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="120" mass="13567" checksum="4BD127B35562535F" modified="2000-10-01" version="1">MDILTIMKRIKSGKDITPSMVTRFVELVGNKELFYDPLPIKLSSSTLTGRNINYSEEHVKSMIVIIYGYLPSIIKKKIFVNKISKLLSIPPDDALKRIFGDTSEIGVNTFIKKFLAELTS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J541</accession>
    <name>A28_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Envelope protein A28 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Protein FPV192</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV192</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Envelope protein required for virus entry into host cell and for cell-cell fusion (syncytium formation).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Virion membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">Component of the intracellular mature virion (IMV) membrane.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Contains two intramolecular disulfide bonds. They are created by the viral disulfide bond formation pathway, a poxvirus-specific pathway that operates on the cytoplasmic side of the MV membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the poxviridae A28 protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039155.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486764"/>
    <dbReference type="KEGG" id="vg:1486764"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019031">
        <property type="term" value="C:viral envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055036">
        <property type="term" value="C:virion membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039663">
        <property type="term" value="P:membrane fusion involved in viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046718">
        <property type="term" value="P:viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007664">
        <property type="entry name" value="Poxvirus_A28"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04584">
        <property type="entry name" value="Pox_A28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-1168">Fusion of virus membrane with host membrane</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0735">Signal-anchor</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0261">Viral envelope protein</keyword>
    <keyword id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <keyword id="KW-1160">Virus entry into host cell</keyword>
    <feature type="chain" id="PRO_0000099291" description="Envelope protein A28 homolog">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Signal-anchor for type II membrane protein" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="topological domain" description="Virion surface" evidence="2">
        <location>
            <begin position="22"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="141" mass="16114" checksum="26511BF203424318" modified="2000-10-01" version="1">MDALFVFIIILATAVICLFLFQAYTIYDNYHNIIEFNEKYGGLEYSRSPGGLYIDKRVFDPNDSETDPKAKWRCVNYNNNQYASASKFGYLATSSRNPVLFTNLEDCVYYNYTRGEIGTIWNPCAEYGEGSAECSTLKSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J543</accession>
    <name>Q9J543_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV190 A type inclusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV190</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039153.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486762"/>
    <dbReference type="KEGG" id="vg:1486762"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009285">
        <property type="entry name" value="Orthopox_A30L/A26L"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06086">
        <property type="entry name" value="Pox_A30L_A26L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="620" mass="74902" checksum="333313F5CCF81504" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2021-04-07" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J545</accession>
    <name>Q9J545_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Intermediate transcription factor 3 large subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FPV188</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">NVSL</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts with RNA polymerase to initiate transcription from intermediate gene promoters.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviruses A23 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039151.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486760"/>
    <dbReference type="KEGG" id="vg:1486760"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008789">
        <property type="entry name" value="Poxvirus_intermed-TF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05718">
        <property type="entry name" value="Pox_int_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AAF44532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="383" mass="44794" checksum="CC40CF33BB36B417" modified="2000-10-01" version="1">MYELFSYLHEIEDEYIRTIFNFHIKKCDEISNIYNIIMTKIKDAKNFNDVIDERFNKTIKKLIYCDIKTTKHIINQSCYPTKNKQIKKISKINQYFDINIISDTPASKRTKEIFLSDRSSLVSYIKTSNKKCKIDYGELKKTINSHNRSIYYSGRRSDEYMSTEVHKDQKNPWIKSISKKLTLDIENQSITTRGKSSILQTIEIIYVNRTCIKIFKDSTIHVILSKDKSETNCVDTINKLFDTYSILFDLITDITGNEKFLEYKAVASDIVSTDNFNEKILIIKKHPNMYGIHNFKIGMFNITYKLSIDMIIFPSLMEFNSKIKFFKGKKLNIVALSSLQDCIKYVKEAKGILCMMKKKSEELEEIDIITASVDRLKNVIINI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2021-06-02" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J546</accession>
    <name>RUVV_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Holliday junction resolvase</fullName>
            <ecNumber>3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV187</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Nuclease that specifically cleaves and resolves four-way DNA Holliday junctions into linear duplex products.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RuvC family. Poxviruses-type subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039150.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="PDB" id="6P7A">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="3.08 A"/>
        <property type="chains" value="A/B=1-148"/>
    </dbReference>
    <dbReference type="PDB" id="6P7B">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="3.32 A"/>
        <property type="chains" value="A/B/C/D=1-149"/>
    </dbReference>
    <dbReference type="PDBsum" id="6P7A"/>
    <dbReference type="PDBsum" id="6P7B"/>
    <dbReference type="BMRB" id="Q9J546"/>
    <dbReference type="SMR" id="Q9J546"/>
    <dbReference type="GeneID" id="1486759"/>
    <dbReference type="KEGG" id="vg:1486759"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006932">
        <property type="entry name" value="HJ-resolvase_A22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04848">
        <property type="entry name" value="Pox_A22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0002">3D-structure</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0233">DNA recombination</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000183159" description="Holliday junction resolvase">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="strand" evidence="3">
        <location>
            <begin position="2"/>
            <end position="7"/>
        </location>
    </feature>
    <feature type="strand" evidence="3">
        <location>
            <begin position="10"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="strand" evidence="3">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="turn" evidence="3">
        <location>
            <begin position="22"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="strand" evidence="3">
        <location>
            <begin position="26"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="strand" evidence="4">
        <location>
            <begin position="38"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="helix" evidence="3">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="strand" evidence="3">
        <location>
            <begin position="55"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="strand" evidence="4">
        <location>
            <begin position="64"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="helix" evidence="3">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="turn" evidence="3">
        <location>
            <begin position="79"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="strand" evidence="3">
        <location>
            <begin position="85"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="helix" evidence="3">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="helix" evidence="3">
        <location>
            <begin position="114"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="helix" evidence="3">
        <location>
            <begin position="120"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="helix" evidence="3">
        <location>
            <begin position="131"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <evidence type="ECO:0007829" key="3">
        <source>
            <dbReference type="PDB" id="6P7A"/>
        </source>
    </evidence>
    <evidence type="ECO:0007829" key="4">
        <source>
            <dbReference type="PDB" id="6P7B"/>
        </source>
    </evidence>
    <sequence length="156" mass="18154" checksum="C6C9707548BBC331" modified="2000-10-01" version="1">MIICSVDIGIKNPAYAIFNYDNTSNTIKLIAIEKSDWTKNWERSVARDLTRYNPDVVILEKQGFKSPNSKIIYFIKGFFYNSNTKVIVRNPTFKGGSYRNRKKQSIDVFIQKISEYTDYKNDILNKYTKLDDIADSFNLGLSYMESLLKKCKISKD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-12-02" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J551</accession>
    <name>A17_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Virion membrane protein A17 precursor homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV182</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Envelope protein which participates in virus morphogenesis. Needed for an early step in viral crescent membrane formation by interacting with D13 scaffold protein. Its interaction with D13 scaffold protein leads to the formation of rigid, crescent-shaped membranes that assemble around the cytoplasmic virus factory. Membrane anchor for the protein A27. A17-A27 virus envelope protein might be involved in fusion or attachment, and can further associate to A26.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts (via N-terminus) with D13 scaffold; this interaction helps D13 to associate with membranes. Interacts with A14. Interacts with A27; this interaction allows A27 to be anchored in the mature virion (MV) membrane. Part of a complex composed of A17, A25, A26 and A27.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Virion membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">The 22 kDa precursor is probably cleaved by the I7 protease during virus maturation.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Phosphorylated on tyrosine and threonine. Its phosphorylation state is regulated by the F10 kinase and the H1 phosphatase (By similarity). Phosphorylation by F10 kinase seems to be required to form the membranes associated with IV.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the chordopoxvirinae A17 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039145.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486754"/>
    <dbReference type="KEGG" id="vg:1486754"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007977">
        <property type="entry name" value="Poxvirus_P21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05313">
        <property type="entry name" value="Pox_P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0597">Phosphoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0261">Viral envelope protein</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099260" description="Virion membrane protein A17 precursor homolog">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="topological domain" description="Virion surface" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="topological domain" description="Intravirion" evidence="1">
        <location>
            <begin position="77"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="topological domain" description="Virion surface" evidence="1">
        <location>
            <begin position="167"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by I7 protease" evidence="1">
        <location>
            <begin position="18"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by I7 protease" evidence="1">
        <location>
            <begin position="182"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphotyrosine" evidence="1">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Interchain" evidence="1">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="198" mass="21966" checksum="C75FDCED33A57F2E" modified="2000-10-01" version="1">MDNNYLNYYNVFEEFDAGAGIKEKELFTEEQQLSFLPKKGLGNGGFDGVERLYSNIINNNDIKSLLALIMLVFAINTNSLVALIFIILSAIFVPVPALIIAYCIALHLKNGSDATHVGISILLMLASAVTIYLTSTSKISKGFKRAIDVVLLVILGFYIVKIYGIDRQISIPSRRYCRQMSGPSSLENLNAFQTHSNY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J553</accession>
    <name>A15_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Core protein A15 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV180</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Late protein which is a part of a large complex required for early virion morphogenesis. This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions. A15 is required for the stability and kinase activity of F10.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of a complex composed of A30, G7, F10 kinase, A15, D2, D3, and J1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location>Virion</location>
        </subcellularLocation>
        <text evidence="1">Localizes in cytoplasmic virus factories and present in the virion core.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae A15 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039143.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486728"/>
    <dbReference type="KEGG" id="vg:1486728"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008445">
        <property type="entry name" value="A15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05846">
        <property type="entry name" value="Chordopox_A15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1035">Host cytoplasm</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099249" description="Core protein A15 homolog">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="97" mass="11578" checksum="583B5E4FFFBC3B02" modified="2000-10-01" version="1">MYIENNSLVLIIPETNSITPQLFTIHDNKPICVCSRYSLIPSKKENVQISYIDNIHMYFRSFKNLYLVNPRNHDIIKVFNFLKNYKWGGNFYLLFNV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-08-12" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J555</accession>
    <name>A13_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Virion membrane protein A13 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV178</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Essential for the encapsidation of DNA into immature virions (IV) and the subsequent maturation of IV into mature virions (MV).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">The mature virion is located in the cytoplasm of infected cells and is probably released by cell lysis.</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the chordopoxvirinae A13 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039141.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J555"/>
    <dbReference type="GeneID" id="1486726"/>
    <dbReference type="KEGG" id="vg:1486726"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009236">
        <property type="entry name" value="Chordopox_A13L"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05961">
        <property type="entry name" value="Chordopox_A13L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099241" description="Virion membrane protein A13 homolog">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="topological domain" description="Virion surface" evidence="2">
        <location>
            <begin position="22"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="71" mass="8018" checksum="FF5FE854B1DA2E7C" modified="2000-10-01" version="1">MGIIDTFVITAVTVIIFCLLIYAAYKRYKCIPSPDDRDKVLKSTLNDDTLFNQTLTPDQVKALHRLVTSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J565</accession>
    <name>Q9J565_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV166 Molluscum contagiosum virus MC105L homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV166</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039129.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486714"/>
    <dbReference type="KEGG" id="vg:1486714"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007952">
        <property type="entry name" value="Poxvirus_A3L"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05288">
        <property type="entry name" value="Pox_A3L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="72" mass="8609" checksum="AC9A531FB7D51FD7" modified="2000-10-01" version="1">MSEYKYSIDPPVRCSNCSNNLVEYLKSDRQLIKLMLNNNEYKKNILKQFLIFSRNKTLLTKILDPEIRRVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2021-06-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J567</accession>
    <name>Q9J567_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein FPV164</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV164</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039127.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486712"/>
    <dbReference type="KEGG" id="vg:1486712"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="383" mass="43805" checksum="61B1F8AEBF5E316D" modified="2000-10-01" version="1">MIRIIILSLLFINVTTDSQESSKNIQNVLHVTEYSRTGVTACSLHCFDRSKGLDQPKTFILPGKYSNNSIKLEVAIDTYKKDSDFSYSHPCQIFQFCVSGNFSGKRFDHYLYGYTISGFIDIAPKYYSGMSISTITVMPLQEGSLKHDDADDYDYDDDCVPYKETQPRHMPESVIKEGCKPIPLPRYDENDDPTCIMYWDHSWDNYCNVGFFNSLQSDHNPLVFPLTSYSDINNAFHAFQSSYCRSLGFNQSYSVCVSIGDTPFEVTYHSYESVTVDQLLQEIKTLYGEDAVYGLPFRNITIMARTRIQSLPLTNNTCIPKQDDADDVDDADDVDDADDADDDDDYELYVETTPRVPTARKKPVTEEYNDIFSSFDNFDMKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J568</accession>
    <name>Q9J568_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ORF FPV163 N1R/p28 gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FPV163</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039126.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486711"/>
    <dbReference type="KEGG" id="vg:1486711"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017880">
        <property type="entry name" value="KilA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA_N/APSES_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51301">
        <property type="entry name" value="KILA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KilA-N" evidence="2">
        <location>
            <begin position="14"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="165"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AAF44507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="263" mass="31632" checksum="91442DB8E3164E94" modified="2000-10-01" version="1">MNTLPYIIQDIDSHFCYIKYDGITLTMMKDNGYINATQLCMLGNKDFKEWIKLDHSIELIKEIEKNINKETTKYVKAVISVRSDYYNSETSNDIKGFYIHGNIMPHICAWISSKFAIKVSNIVHNYLNDRYVQNDKEEIHQEPDKDIKYIKKQCKLMREIRILFKKNYTRELDELKKVRELYYEKNKGLEEYIDKLEYSYTQRMKELTLSIDELKNSNKQLKNKLENIEKRIKCINPPTESSKNVIYDRFKKLYHILTFRKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J570</accession>
    <name>Q9J570_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV161 N1R/p28 gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV161</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039124.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486709"/>
    <dbReference type="KEGG" id="vg:1486709"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017880">
        <property type="entry name" value="KilA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA_N/APSES_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51301">
        <property type="entry name" value="KILA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KilA-N" evidence="1">
        <location>
            <begin position="14"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="157" mass="18305" checksum="1BE24D453122F969" modified="2000-10-01" version="1">MDKRYISTRKLNDGFLILYYDSIEIIVMSCNHFINISALLAKKNKDFNEWLKIESFREIIDTLDKINYDLGQRYCEEPYGASHSSVIIEVKASNLIDDRTAGFYVHKDLIPYILTCISIPFSLKVVRVLDTYIGEKLENRIKLSQSMDLETNNSYNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J572</accession>
    <name>Q9J572_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV159 N1R/p28 gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV159</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039122.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486707"/>
    <dbReference type="KEGG" id="vg:1486707"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017880">
        <property type="entry name" value="KilA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA_N/APSES_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="SSF54616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51301">
        <property type="entry name" value="KILA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KilA-N" evidence="1">
        <location>
            <begin position="11"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="241" mass="28254" checksum="2573B31FAE58C7FD" modified="2000-10-01" version="1">MSTITCYGNDKFSYIIYDKIKIIIMKSNNYVNATRLCELRGRKFTNWKKLSESKILVDNVKKINDKTNQLKTDMIIYVKDIDHKGRDTCGYYVHQDLVSSISNWISPLFAVKVNKIINYYICNEYDIRLSEMESDMTEVIDVVDKLVGGYNDEIAEIIYLFNKFIEKYIANISLSTELSSILNNFINFNKKYNNDIKDIKSLILDLKNTSIKLDKKLFDKDNNESNDEKLETEVDKLIFFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J575</accession>
    <name>Q9J575_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ORF FPV155 N1R/p28 gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FPV155</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039118.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486703"/>
    <dbReference type="KEGG" id="vg:1486703"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017880">
        <property type="entry name" value="KilA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA_N/APSES_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51301">
        <property type="entry name" value="KILA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KilA-N" evidence="2">
        <location>
            <begin position="14"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="209"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AAF44499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="408" mass="49034" checksum="F088CFF650F79C34" modified="2000-10-01" version="1">MMFNSMITGYIDEEFCYIQYSGFHLVMMISNCYINASKLCDTKDFKKWLRLDSSLSLLQEIENTNFPSEKKFSIKNSKSVIILEKYYHEEVEGYYIHPDILPHIVGWLSPTFAISMSKFINGYISNSFTITEKDDKKYNTLPPSSSYKQGDRNCFIDMLNEMTNKHLNDITELKTHYREQKRELKYQNTVLSSKITELKNVNDEFRYRIKHFDDSIKEIKDENNTLKSNIKITEKHNKELQRDNNRLKTLLRELYEKNTSLQNNITELRETIARETKELHNQVIELSKDKGIEPIEEYRVDRCFVRNRLHRSNKNNYIIIFQHKKDLFTFKYFKLHIRKVCIELFNYRESHNLFLIIYEPTNKSIIRFKNMLENNEHIELKDNNFKITDTRYTVINILKDINKIFSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J577</accession>
    <name>Q9J577_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV153</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV153</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039116.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486701"/>
    <dbReference type="KEGG" id="vg:1486701"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="208" mass="24180" checksum="76F0BE8651E8ECFF" modified="2000-10-01" version="1">MILAWKIIYLAILLYIPTERLVLSHTVITRSKLSTEDNEIDDVPTCPYRMFNKKKIMGPIVSVKSPDNPTGPIMALDAYHNYTSCKYNQYCTFFDFCMAGNTTIRFGRQKINLIYFVFIEAVTRDDYTKITQEVTLKHLDDVRFKPVSVTFAALYKQFVKMSAYHECNKTGFKKPVRDSCRKDSNSAIQYSNEQKSHYNFLLKSSKKI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J579</accession>
    <name>DCK2_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Probable deoxycytidine kinase FPV151</fullName>
            <shortName>dCK</shortName>
            <ecNumber>2.7.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV151</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction>
            <text>2'-deoxycytidine + a ribonucleoside 5'-triphosphate = a ribonucleoside 5'-diphosphate + dCMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="EC" id="2.7.1.74"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DCK/DGK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.74"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039114.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J579"/>
    <dbReference type="GeneID" id="1486699"/>
    <dbReference type="KEGG" id="vg:1486699"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004137">
        <property type="term" value="F:deoxycytidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01673">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002624">
        <property type="entry name" value="DCK/DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031314">
        <property type="entry name" value="DNK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01712">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000705">
        <property type="entry name" value="DNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000175094" description="Probable deoxycytidine kinase FPV151">
        <location>
            <begin position="1"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="30"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="235" mass="27678" checksum="60AC94B9B0B956D4" modified="2000-10-01" version="1">MAFQELCCSNLLKFENCSLLETHKKISIEGNISAGKSTLINILSDNGYNVVQEPLEQWRGNNLLDKLYKDPSRWAYTFQSHAFWTRTKTYIDALNKNKGNIILERSVFSDKYIFATALHDIGYIDDTEWNIYNEYSKWMTEFMDIKIDGIIYLKTSPDICYKRMLNRARHEENTVKIDYLNLLHDKHEKWLSENNEHEFKVPVLEINGDGDFIDDSNRQSSILSNIYDFISELYI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J586</accession>
    <name>H7_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Late protein H7 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV144</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Contributes to the formation of crescents and immature virions (IV).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">Probably transitorily part of the membrane of crescents during immature virions formation. Not incorporated into virions. Probably synthesized, but not retained in viral factories (By similarity).</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the chordopoxvirinae H7 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039107.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J586"/>
    <dbReference type="GeneID" id="1486692"/>
    <dbReference type="KEGG" id="vg:1486692"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006872">
        <property type="entry name" value="Poxvirus_H7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04787">
        <property type="entry name" value="Pox_H7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000099556" description="Late protein H7 homolog">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="152" mass="17733" checksum="3235C8671DCB7E1A" modified="2000-10-01" version="1">MDHKSRMLLDTIFKDMLNTKDVYALIKYIFKKDPVETIFSKKDDDIFIDFVYNDNVLASDYLGMKTTKVEDCCSCRKVVAVEYMNTSIIDNDLEGYIKQSDKLKRFIKLYNKNNAIKKARNIKSRQKMLKDAGIDDIGYEFIKDAIGLISRK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J589</accession>
    <name>RAP94_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>RNA polymerase-associated transcription-specificity factor RAP94</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Protein H4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>RPO-associated protein of 94 kDa</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">RAP94</name>
        <name type="ordered locus">FPV141</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-directed RNA polymerase-associated factor required for the transcription of viral early genes as well as for transcription termination. Within minutes after virus entry, recruits the core RNA polymerase, the early transcription factor (ETF) and other enzymes needed for transcription initiation, elongation, and termination thereby allowing synthesis of early mRNAs which are extruded through pores in the core particle. Recruits the multifunctional J3 protein, with poly(A) polymerase-stimulatory, cap nucleoside-2'-O-methyltransferase, and transcription elongation activities. Interacts with NPH-I, a DNA-dependent ATPase required for the termination of early transcripts. Acts as a transcription termination factor by binding, together with the capping enzyme/VTF, to the termination motif 5'-UUUUUNU-3' in the nascent mRNA. Involved as well in the packaging of RNA polymerase and other components needed for early transcription in assembling virus particles.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the early transcription complex composed of ETF, RAP94, and the DNA-directed RNA polymerase. Interacts (via N-terminus) with NPH-I. Interacts with J3. Interacts with ETF heterodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Virion</location>
        </subcellularLocation>
        <text evidence="1">All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome.</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">Interacts with ETF via its N-terminus and with DNA-directed RNA polymerase via its C-terminus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviridae protein RAP94 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039104.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J589"/>
    <dbReference type="GeneID" id="1486689"/>
    <dbReference type="KEGG" id="vg:1486689"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004974">
        <property type="entry name" value="Pox_Rap94"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03294">
        <property type="entry name" value="Pox_Rap94"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0806">Transcription termination</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099123" description="RNA polymerase-associated transcription-specificity factor RAP94">
        <location>
            <begin position="1"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with NPH-I; required for transcription termination" evidence="1">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with J3" evidence="1">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="798" mass="95221" checksum="2A3ED2D453537BD3" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J593</accession>
    <name>RP147_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>DNA-directed RNA polymerase 147 kDa polypeptide</fullName>
            <ecNumber>2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">RPO147</name>
        <name type="ordered locus">FPV137</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. DNA-dependent RNA polymerase associates with the early transcription factor (ETF) thereby allowing the early genes transcription. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The DNA-dependent RNA polymerase used for intermediate and late genes expression consists of eight subunits (147) kDa, (133) kDa, (35) kDa, (30) kDa, (22) kDa, (19) kDa, (18) kDa and (7) kDa totalling more than 500 kDa in mass. The same holoenzyme, with the addition of the transcription-specificity factor RAP94, is used for early gene expression.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Virion</location>
        </subcellularLocation>
        <text evidence="1">All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviridae DNA-directed RNA polymerase 147 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039100.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J593"/>
    <dbReference type="GeneID" id="1486685"/>
    <dbReference type="KEGG" id="vg:1486685"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000073922" description="DNA-directed RNA polymerase 147 kDa polypeptide">
        <location>
            <begin position="1"/>
            <end position="1287"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="1287" mass="147998" checksum="B9DC191393999E62" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J597</accession>
    <name>Q9J597_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ORF FPV125 V-type Ig domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FPV125</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039088.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486673"/>
    <dbReference type="KEGG" id="vg:1486673"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013151">
        <property type="entry name" value="Immunoglobulin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00047">
        <property type="entry name" value="ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="SSF48726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="39"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="251"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AAF44469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="345" mass="39027" checksum="2283509E1700A8E5" modified="2000-10-01" version="1">MLYRLYFTYYNDGHKKQLMLIVFLSFINLLQSFVLVNTPSVYIIVPRNSSINLTCDFTDDKGYGIDAVRVTWTRSDKRIEEEIETTWNETSQVGETVLHVPSVSEEEEKFRCLVYVNLSVDYKNIKIQTIDITQKVNLDSVLEIIPPSKQVDICDGPPLKLNCSFKFPNWCLKHQVKVEWWEYNNDTLAWKKHVDGISWVATKGGGTGWLNISNPGVETTFLCVVTCGYIGNSGVRVSVPVPVHKGQKIQPRHSQYPAVKGMSVILVCNIDDSSYSESGWWFNGTNIDKGNKYTLSNKQKSMELVIGNVGDEDKGNYTCWVAKDGSWDAASVNVYITEEDIDGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J598</accession>
    <name>Q9J598_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ORF FPV124 N1R/p28 gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FPV124</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039087.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486672"/>
    <dbReference type="KEGG" id="vg:1486672"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022549">
        <property type="entry name" value="DUF3627"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017880">
        <property type="entry name" value="KilA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA_N/APSES_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12299">
        <property type="entry name" value="DUF3627"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51301">
        <property type="entry name" value="KILA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KilA-N" evidence="2">
        <location>
            <begin position="14"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="138"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AAF44468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="289" mass="34574" checksum="74D0E68399240E78" modified="2000-10-01" version="1">MDFSDLVTREIDDRFCYIKYDKFDLIMMKENRFINATKLCKLGGKDFHRWKRLDGSKELMIKVNEMNEMWKSAPPPPDLGGIIIEVNGSNQYTEYDIAGSYVHQDLIPHIASWISPLFALKVSKIISCYVSGKYEFKLKEKENKIEELLDLLHKFNNKYDKDTLELKELYREQRKEAKSLRKINERIEEKYDKDTRELKQGLKELKDENKELKFELKKIEERLRDKVINPFSPNKHHRLVILQKKIDNNSFKTLRLQAERLNQEMNKYKTNILYFLMHTNLTQYPVLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5A0</accession>
    <name>Q9J5A0_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ORF FPV122 variola B22R gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FPV122</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039085.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486670"/>
    <dbReference type="KEGG" id="vg:1486670"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007490">
        <property type="entry name" value="Poxvirus_B22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025128">
        <property type="entry name" value="Poxvirus_B22R_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025133">
        <property type="entry name" value="Poxvirus_B22R_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04395">
        <property type="entry name" value="Poxvirus_B22R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13168">
        <property type="entry name" value="Poxvirus_B22R_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13169">
        <property type="entry name" value="Poxvirus_B22R_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poxvirus_B22R_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Poxvirus_B22R_C" evidence="1">
        <location>
            <begin position="920"/>
            <end position="1114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AAF44466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="1870" mass="211758" checksum="2423D319743D3F2F" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5A1</accession>
    <name>Q9J5A1_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV121 CC chemokine gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV121</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039084.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486669"/>
    <dbReference type="KEGG" id="vg:1486669"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="121" mass="13125" checksum="521F6C5AC4852D91" modified="2000-10-01" version="1">MDTTKRMWPLQLCALIAICFTSTTVSAASGDGCCPYGFSPDGTDVPVWNLLNCTKIPDNCEKKGFLFHYKSGGGTCGTGDEDWFSPHSLMNDLCNNGLTAIVKRTMSGDCNCKCTCDMEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-01-19" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5A2</accession>
    <name>Q9J5A2_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Assembly protein G7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">FPV120</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">NVSL</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Late protein which is a part of a large complex required for early virion morphogenesis. This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of a complex composed of A30, G7, F10 kinase, A15, D2, D3, and J1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae G7 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039083.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486668"/>
    <dbReference type="KEGG" id="vg:1486668"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008787">
        <property type="entry name" value="Poxvirus_G7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05503">
        <property type="entry name" value="Pox_G7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0946">Virion</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AAF44464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="343" mass="39058" checksum="0E662E335E723F8D" modified="2000-10-01" version="1">MEDQKQSRIFNMVSKSLIETLLKDYLDDKAIAGIVARAKYIYNSSNRDSIINSIYQKCESDISIPTIAGVKSLVDKTRNYERHVQDEIEFNELRNILTRLTHNKSFFITCNYLINTTAATLLTLILANQLIHAAKIVMEIENYLFDSKKRPSSEVSDLLDMKYAILKFAQYKIFPILTGQQDIETIAGGKVMSFSEEIDIIIDLPLKSPKLDKMYKTICEIGLCKDTYPEYIAGLKIEEVGEEAENTVKNQLATYIANNNKVLDMAYKYSKGHDLDGAVISPITEDRIRLTNNDLRKFAILDYLYTIRVLANCIKKKKSFKTKKPGTTLTINSPYKIVTVPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5A3</accession>
    <name>Q9J5A3_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV119</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV119</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039082.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486667"/>
    <dbReference type="KEGG" id="vg:1486667"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024453">
        <property type="entry name" value="Peptidase_C92"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05708">
        <property type="entry name" value="Peptidase_C92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="188" mass="22019" checksum="3F2039685D5E5C00" modified="2000-10-01" version="1">MDISLFDYVAPGAVILSQSNHSIVNFFNPSEEKHSSLYFGYGIVDFIIKNDINFSINGLNNFTNYIIEFNTSGFAIIPLREFMLDRKYAKVYYYMEGIFPNYRLMEDTVKQAFLHANKEYGFGKDKTYCFKMIADCYLDIGINVKSYKILGKYIYLSQSFCTDDRWTKVLDTLTGENLITRNSYYFIR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5A4</accession>
    <name>RP07_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>DNA-directed RNA polymerase 7 kDa subunit</fullName>
            <ecNumber>2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">RPO7</name>
        <name type="ordered locus">FPV118</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. DNA-dependent RNA polymerase associates with the early transcription factor (ETF) thereby allowing the early genes transcription. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The DNA-dependent RNA polymerase used for intermediate and late genes expression consists of eight subunits 147 kDa, 133 kDa, 35 kDa, 30 kDa, 22 kDa, 19 kDa, 18 kDa and 7 kDa totalling more than 500 kDa in mass. The same holoenzyme, with the addition of the transcription-specificity factor RAP94, is used for early gene expression.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Virion</location>
        </subcellularLocation>
        <text evidence="1">All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the early phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviridae DNA-directed RNA polymerase 7 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039081.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5A4"/>
    <dbReference type="GeneID" id="1486666"/>
    <dbReference type="KEGG" id="vg:1486666"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008448">
        <property type="entry name" value="RNA_pol_7kDa_chordopoxvir"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05864">
        <property type="entry name" value="Chordopox_RPO7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0244">Early protein</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099160" description="DNA-directed RNA polymerase 7 kDa subunit">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="63" mass="7351" checksum="7555329482D9EDA3" modified="2000-10-01" version="1">MVFPLVCSTCGRDLSEARYRLLVEQMELKKVVITYSRKCCRLKLSTQIEPYRNLTVQPSLDIN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-12-02" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5A5</accession>
    <name>V117_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein FPV117</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV117</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the poxviruses G5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039080.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486665"/>
    <dbReference type="KEGG" id="vg:1486665"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007678">
        <property type="entry name" value="Poxvirus_G5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04599">
        <property type="entry name" value="Pox_G5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099533" description="Protein FPV117">
        <location>
            <begin position="1"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="440" mass="51486" checksum="C330B8A480D09081" modified="2000-10-01" version="1">MGIKNLKSVLLLKHSLKVLDSAVKSKEIYVDFLGLFMAIAYSVTSTAMLHHIIKEKFKFIHSIADNVTVFVDRGSISLKTSLREKRKQSLKNQYKRKQEELKNLEIAIDNLSVDDEMYEEQKESLFSKIDKNSYYMFLADKKNMEAIITDVLASLKNTEIYYCDHIDAEFMMCCRAREYYTNNGTWPSILSSDQDTICLVCVDTQEKILYDTKSVYKLSPNKYTSYLTKLIVLTNGCDFFRGLYGISINKDNYMRYELFTEFNRENAFRSIAHKNYSLNNSNTDENIDEISTNIDVIFDFINHYTSLNEDAYKFEDLPDIRVKDFLDVMVRSKWYEAKNKYDLGSDILQNIYNVYKVHRRNYEKEKETNILKMIESYKYRNIKINTITTFIKLLGIETSDSICVLGILAPSELYIGFEGRFYFNKTSIIKSSPKLININI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5A7</accession>
    <name>V155_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV115</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV115</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039078.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5A7"/>
    <dbReference type="GeneID" id="1486663"/>
    <dbReference type="KEGG" id="vg:1486663"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067111" description="Putative ankyrin repeat protein FPV115">
        <location>
            <begin position="1"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="157"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="218"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="251"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="285"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 6">
        <location>
            <begin position="316"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 7">
        <location>
            <begin position="347"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 8">
        <location>
            <begin position="378"/>
            <end position="407"/>
        </location>
    </feature>
    <sequence length="542" mass="62057" checksum="CBB71D6E04A06629" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5A8</accession>
    <name>Q9J5A8_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV114 HAL3 domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV114</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039077.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486662"/>
    <dbReference type="KEGG" id="vg:1486662"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="1">
        <location>
            <begin position="5"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="183" mass="20779" checksum="090E039BC0CE27D3" modified="2000-10-01" version="1">MSRIKILIGITGSVAAVKLPDLIKELTRLENIELRIVATENSMKFTDQKTIGIPIYTDKDEWTTWKKIPDPVLHIELRRWADVFIIAPLTANTLAKIANGICDNLLTSIVRAWDTNKPLIFCPAMNTLMWEHPITEKHIDTLKYMGFIEIECIEKKLACGDVGNGAMAEVAEIYRVVRDIMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5B0</accession>
    <name>Q9J5B0_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ORF FPV112 Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FPV112</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">NVSL</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Interacts with G4; this interaction involves formation of a transient disulfide-bonded intermediate, allowing disulfide bond transfer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Virion membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039075.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5B0"/>
    <dbReference type="GeneID" id="1486660"/>
    <dbReference type="KEGG" id="vg:1486660"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019031">
        <property type="term" value="C:viral envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055036">
        <property type="term" value="C:virion membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003472">
        <property type="entry name" value="Virion_mem_poxvirus_L1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02442">
        <property type="entry name" value="L1R_F9L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0261">Viral envelope protein</keyword>
    <keyword evidence="4" id="KW-0946">Virion</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AAF44456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="213" mass="24380" checksum="A8CAE4B1DECA4CF9" modified="2000-10-01" version="1">MENQQVISNLYYLFSEKYLEKLNQHPDTSNVRCGIHIGYLSGEAKNCIVSIINACNSNEQKSFQLLIESLIETIENLPEKQQKEIAKSIGINIDDYKAGKKTELQQHCEAYANLTQHIDIQHFNIGTCYSPNDKYTDIKIINTGSALSNCGVEIILNKIKTNNPIVPIDNKLSMESFSIKWFIIYIVLCVLILLLLGYIYRTVRIKYTYGVYI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5B1</accession>
    <name>V111_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Probable serine/threonine-protein kinase FPV111</fullName>
            <ecNumber>2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV111</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction>
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Poxviruses subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039074.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486659"/>
    <dbReference type="KEGG" id="vg:1486659"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008790">
        <property type="entry name" value="Poxvirus_ser/thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05445">
        <property type="entry name" value="Pox_ser-thr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015695">
        <property type="entry name" value="STPK_F10L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000086786" description="Probable serine/threonine-protein kinase FPV111">
        <location>
            <begin position="1"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="87"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1 2">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="93"/>
            <end position="101"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10027"/>
        </source>
    </evidence>
    <sequence length="444" mass="52848" checksum="F8490899B8615971" modified="2000-10-01" version="1">MEFPDIHAYNSTKYLEDGDTTILGDTIQFQFIYENIDNKEHISLPKIKIFKYFRDKISFETLDRIIKNDYINPSYFQLKDKKFCAHNRDFYHLSTGGYGIIFRMEKYVVKFVFEDGSKKYKPMEVTSEFTIPRFLYNNLKGDERKFIVCAIAMGINFKIDFLRTIYYNTMSLMSALFNIMEGEPLENKYSHRKVLRYFAKYKQSNDFVKLISQFYPYVVNSNINVINNFNYLINFFERSRRSNGYFNRGNIIIFPLAKCSAEKITPDNYAQYGFSSIVEYTKFMFLQIALLYIKIYELPCSNFVHLDLKPDNILIFDSKEPINIYVGDMHYVFKEPIRCTLNDFDFSQISEIIPNKKAVTAINKEQNWYYDFHFFSHVLFKVYPEISKDEDFTSLLNEFTICDKYICENFRLQVNKLPSISFLINIVSRDIFSKWIDGKSTSHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5B3</accession>
    <name>Q9J5B3_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ORF FPV107 variola B22R gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FPV107</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039070.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486655"/>
    <dbReference type="KEGG" id="vg:1486655"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007490">
        <property type="entry name" value="Poxvirus_B22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025128">
        <property type="entry name" value="Poxvirus_B22R_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025133">
        <property type="entry name" value="Poxvirus_B22R_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04395">
        <property type="entry name" value="Poxvirus_B22R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13168">
        <property type="entry name" value="Poxvirus_B22R_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13169">
        <property type="entry name" value="Poxvirus_B22R_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poxvirus_B22R_N" evidence="3">
        <location>
            <begin position="18"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Poxvirus_B22R_C" evidence="2">
        <location>
            <begin position="824"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="730"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AAF44451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="1777" mass="200811" checksum="E776A0C1E31DB1EC" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5B4</accession>
    <name>Q9J5B4_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV106</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV106</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039069.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486654"/>
    <dbReference type="KEGG" id="vg:1486654"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="71" mass="8297" checksum="351E76556C42A5E5" modified="2000-10-01" version="1">MYVSELDLSKGFMVISDIKTNEIINIDLYNQKGFSTINNNHEQNHLNRLSKSCSDIHNKIMCKAEMRKLCY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-12-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5B5</accession>
    <name>F15_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein F15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV105</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the poxviridae F15 protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039068.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5B5"/>
    <dbReference type="GeneID" id="1486653"/>
    <dbReference type="KEGG" id="vg:1486653"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007675">
        <property type="entry name" value="Poxvirus_F15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04596">
        <property type="entry name" value="Pox_F15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015694">
        <property type="entry name" value="VAC_F15L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099514" description="Protein F15">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="148" mass="17723" checksum="492B0CB93D66B02A" modified="2000-10-01" version="1">MNVSRLEELISMNPFSDMENIVINEKEKCILGNRCFVKLSEVYNMPMCCIDTNQCLTMNRFKFSLNELLYTPFYYKQLQYQYLTPQFIFRCIQEANENNMSCYYCYTKKKEHNGLNIDIFIPTANSKSYIVIGLRIKDFWKQSFKVNK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5B9</accession>
    <name>E2_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein E2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV101</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the poxviridae E2 protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039064.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5B9"/>
    <dbReference type="PRIDE" id="Q9J5B9"/>
    <dbReference type="GeneID" id="1486649"/>
    <dbReference type="KEGG" id="vg:1486649"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007585">
        <property type="entry name" value="Poxvirus_E2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021155">
        <property type="entry name" value="Poxvirus_E2/O1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04497">
        <property type="entry name" value="Pox_E2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015692">
        <property type="entry name" value="VAC_E2L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099446" description="Protein E2 homolog">
        <location>
            <begin position="1"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="717" mass="85047" checksum="25DD7DD803793BB4" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2021-06-02" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5C2</accession>
    <name>Q9J5C2_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ORF FPV098 variola B22R gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">FPV098</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039061.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486646"/>
    <dbReference type="KEGG" id="vg:1486646"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007490">
        <property type="entry name" value="Poxvirus_B22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025128">
        <property type="entry name" value="Poxvirus_B22R_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025133">
        <property type="entry name" value="Poxvirus_B22R_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04395">
        <property type="entry name" value="Poxvirus_B22R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13168">
        <property type="entry name" value="Poxvirus_B22R_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13169">
        <property type="entry name" value="Poxvirus_B22R_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poxvirus_B22R_N" evidence="4">
        <location>
            <begin position="27"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Poxvirus_B22R_C" evidence="3">
        <location>
            <begin position="842"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="327"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="374"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="669"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="722"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="528"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="385"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="677"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AAF44442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="1802" mass="203222" checksum="9B25E3166DEC12ED" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5C4</accession>
    <name>E6_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein E6 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV096</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Late protein which may play a role in the virion morphogenesis and have therefore an indirect role on viral transcription ability.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Localizes in the mature virion (MV).</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae E6 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039059.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="PRIDE" id="Q9J5C4"/>
    <dbReference type="GeneID" id="1486644"/>
    <dbReference type="KEGG" id="vg:1486644"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006749">
        <property type="entry name" value="Pox_E6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04656">
        <property type="entry name" value="Pox_E6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015629">
        <property type="entry name" value="VAC_E6R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099457" description="Protein E6 homolog">
        <location>
            <begin position="1"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="571" mass="67789" checksum="2F1EDCCDEA10CFFB" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5C7</accession>
    <accession>O72895</accession>
    <name>V093_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Probable FAD-linked sulfhydryl oxidase FPV093</fullName>
            <ecNumber>1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV093</name>
        <name type="ORF">FPE10R</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1998" name="Virus Genes" volume="17" first="5" last="9">
            <title>Nucleotide sequence of the 4.3 kbp BamHI-N fragment of fowlpox virus FP9.</title>
            <authorList>
                <person name="Pollitt E."/>
                <person name="Skinner M.A."/>
                <person name="Heaphy S."/>
            </authorList>
            <dbReference type="PubMed" id="9778782"/>
            <dbReference type="DOI" id="10.1023/A:1008045914991"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>O2 + 2 R'C(R)SH = H2O2 + R'C(R)S-S(R)CR'</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviruses E10 family.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2"/>
    <dbReference type="EMBL" id="AJ223385">
        <property type="protein sequence ID" value="CAA11288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039056.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5C7"/>
    <dbReference type="GeneID" id="1486641"/>
    <dbReference type="KEGG" id="vg:1486641"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006890">
        <property type="entry name" value="Sulphydryl_Oase_FAD-link_ERV1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04805">
        <property type="entry name" value="Pox_E10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015696">
        <property type="entry name" value="VAC_E10R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="SSF69000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0274">FAD</keyword>
    <keyword id="KW-0285">Flavoprotein</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099467" description="Probable FAD-linked sulfhydryl oxidase FPV093">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="1">
        <location>
            <begin position="41"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA11288." evidence="2" ref="1">
        <original>S</original>
        <variation>R</variation>
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA11288." evidence="2" ref="1">
        <original>W</original>
        <variation>G</variation>
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA11288." evidence="2" ref="1">
        <original>C</original>
        <variation>R</variation>
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA11288." evidence="2" ref="1">
        <original>FF</original>
        <variation>SS</variation>
        <location>
            <begin position="68"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="94" mass="11252" checksum="401A36D5E96AAAF8" modified="2000-10-01" version="1">MDPRYWGSSFWIVIFIIITKFKHDIETCKRHLYNICKALPCAECKDHALQAIQKNNIMSSNDINYIYFFFISLYNNLVFNPERCIDIKKVKKLI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-05-25" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5D2</accession>
    <name>G3_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein G3 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Protein FPV078</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV078</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry. Also plays a role in cell-cell fusion (syncytium formation).</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of a stable entry-fusion complex (EFC) which is at least composed of proteins A16, A21, A28, G3, G9, H2, J5, and L5. Formation of the viral membrane is necessary for the assembly of the complex. Interacts with L5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Virion membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">Component of the mature virion (MV) membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the chordopoxvirinae G3 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039042.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486626"/>
    <dbReference type="KEGG" id="vg:1486626"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055036">
        <property type="term" value="C:virion membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019064">
        <property type="term" value="P:fusion of virus membrane with host plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046718">
        <property type="term" value="P:viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010367">
        <property type="entry name" value="Poxvirus_G3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06129">
        <property type="entry name" value="Chordopox_G3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1169">Fusion of virus membrane with host cell membrane</keyword>
    <keyword id="KW-1168">Fusion of virus membrane with host membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0735">Signal-anchor</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <keyword id="KW-1160">Virus entry into host cell</keyword>
    <feature type="chain" id="PRO_0000099530" description="Protein G3 homolog">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Signal-anchor" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="topological domain" description="Virion surface" evidence="2">
        <location>
            <begin position="22"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="103" mass="12236" checksum="BCE3BF93F3E79914" modified="2000-10-01" version="1">MTLFLVIFFILFLLLCYFFSFKRTNKMEIGINPIKKIPWSDNEHIFVSSLFTNKDKYLTGPMRLTYRPDSKTAVLDFKGTNYTYYLDNFDDVRKLVPTLLLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5D5</accession>
    <name>Q9J5D5_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV076 beta-Nerve growth factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV076</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039039.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486624"/>
    <dbReference type="KEGG" id="vg:1486624"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002072">
        <property type="entry name" value="Nerve_growth_factor-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00243">
        <property type="entry name" value="NGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="SSF57501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NGF" evidence="1">
        <location>
            <begin position="40"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="144" mass="16330" checksum="152EE31283759DE0" modified="2000-10-01" version="1">MYVTHILVLLTCFQYYHAAVLYDTQTSSNDNTTVYLYEPACELVTTWVDIREVSPVNGTGVSKIEFLGRYSEKGDGYTQYIQMISCMGFPNSTSPCKGIDESRWESYCSTVTEIKKIMYLGENNAVMTKHVSVPVNCVCMVKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5D6</accession>
    <name>Q9J5D6_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ORF FPV075 N1R/p28 gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FPV075</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039038.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486623"/>
    <dbReference type="KEGG" id="vg:1486623"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017880">
        <property type="entry name" value="KilA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA_N/APSES_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51301">
        <property type="entry name" value="KILA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KilA-N" evidence="2">
        <location>
            <begin position="14"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AAF44419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="199" mass="22966" checksum="3AF0243EB7428F1A" modified="2000-10-01" version="1">MEFVPNTVKHIDENFCFINYANIEVIMLKYNGYINATKICDLGNKNFRQWCRLESSKKLIKTLNYKNGIYNKAVLEIGLASNSAYKYELVGTYVHIDLVPHIICWVFPSIALNFSKILNSYLSNSYCTRLKKGSDNEDQIRSGFFSEGISKILYDIHDNEILKLKKNTKKLEEKYEKTNSLINQKISNLEVAVKGLSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5D8</accession>
    <name>Q9J5D8_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV073 Interleukin binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV073</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039036.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486621"/>
    <dbReference type="KEGG" id="vg:1486621"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="174" mass="19732" checksum="65CCC17935CF2DED" modified="2000-10-01" version="1">MMYRTIFILCLIIPVLLNPIDYGDEGDYSTVSYEEDDSDETIFLDLEGYLPENARKNSDGVRECCPVTREDCTYVNITRLPEDINTTSLICVGCGRKGSSARMFWAGPGGKPISEMESVIHKSPVTIPLQNSTFFIRELLVDNKHNGKEFMCLLVESNTTVYRQLLLRHILLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5E1</accession>
    <name>Q9J5E1_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV070 T10 gene product</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV070</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039033.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486618"/>
    <dbReference type="KEGG" id="vg:1486618"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008551">
        <property type="entry name" value="TANGO2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17985">
        <property type="entry name" value="PTHR17985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05742">
        <property type="entry name" value="TANGO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="273" mass="31155" checksum="3DC1D118FE07DC9A" modified="2000-10-01" version="1">MCILFLFFDPHNIYGRFKYIIASNRDEIYSREAIPAKFWNSNGYDVLSGIDVKSGGTWLGINTDGKFSVVTNYLQPYEDPNFISRGNLVSDYLTSNISSREYLCYLSKRGHLYNGFNLITASFSKESDDLYYYSNRSGTAPERLGTGIYGLSNSLLDISWPKVCVGKKVFTDIIHAHKNDLNQESLITELLEMLNDTSPLPIDPRIQEQGQDFIRPMIKEFSSICVRADGYGTRTNTIVTIDSHYSVNFIEKTITDMDTKEFKISRYTFSLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2021-06-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5E3</accession>
    <name>Q9J5E3_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein FPV068</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV068</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039031.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486616"/>
    <dbReference type="KEGG" id="vg:1486616"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="133" mass="14804" checksum="D2E60AC15F57529E" modified="2000-10-01" version="1">MEKKLIQEYEKLKGQEAKDVFTRQLLICHEDMRGRMDNMTKLISDVFRTLAGGSSKAPTEKSDIDTMPPSNDAGSEPQPQPSESKPPEQPSPEPEKDSSSKPSDQPTPEPEKGSSSKPRTDIFSGLRNKEINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5F5</accession>
    <name>Q9J5F5_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ORF FPV048 GNS1/SUR4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FPV048</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">NVSL</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039011.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486596"/>
    <dbReference type="KEGG" id="vg:1486596"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030457">
        <property type="entry name" value="ELO_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="PTHR11157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01188">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AAF44392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="261" mass="31223" checksum="F1B819001ED7C992" modified="2000-10-01" version="1">MSTSLIEFYNWSLTIRDKRVDNWLLMNSPIPTICISTLYLIIVWLGPKWIKTRNAFNIRWLLVLYNFSMVFLNFYILKELFVSSAAKGYSYVCQPIDYSDNVHEVRIARALWLYYISKGIEYLDTVFFILRKKFNQVSFLHVYHHFTMFTLGWIGIKWFAGGQAFFGAQLNSFIHVIMYTYYGMAACGPMFRKYLWWKRYLTIMQLVQFHIAIGHTAMSIYIDCPFPKWIQWSVIIYSISFILLFGNFYFRTYKNSSKKVK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-08-12" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5G1</accession>
    <name>V042_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein FPV042</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV042</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039005.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486590"/>
    <dbReference type="KEGG" id="vg:1486590"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099728" description="Uncharacterized protein FPV042">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <sequence length="85" mass="9560" checksum="8D05C270430AF192" modified="2000-10-01" version="1">MKLFFYLLIVYKKYYSSGGDIETAYNCLISFRLLAVSYVLSSLILEHLGNRIDILEAVWVEDLVNSDPIISHTGANEISEIITSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5G2</accession>
    <name>Q9J5G2_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein FPV041</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV041</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039004.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486589"/>
    <dbReference type="KEGG" id="vg:1486589"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="206" mass="23941" checksum="720B28DC81846FB6" modified="2000-10-01" version="1">MRIIIINVILYVLYHVDAKPISPNIVCRFGRITDIDEYTLGYQRSEYMIPSNKAWKVIRLGKDVSVTLLDTDNYKCYICDINKHKENLPYLNNCKYAGHNVTHSDIYNSLKVMVCRKSTKNSHKKVIYPNSVYYDITYGVKTVYTTGVVVCLIEKEHTWAFTIGHMIIYILALLVIFISLMPLIILYNLFKMGDIEDYDSLDEENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5G6</accession>
    <name>Q9J5G6_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein FPV037</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FPV037</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">NVSL</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TspO/BZRP family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039000.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486585"/>
    <dbReference type="KEGG" id="vg:1486585"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004307">
        <property type="entry name" value="TspO_MBR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03073">
        <property type="entry name" value="TspO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AAF44381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="162" mass="18934" checksum="CA5FA0F3C8BCE63F" modified="2000-10-01" version="1">MTLFEYICDHSYSLISLTLWLIVVKIIEKYSFYNYIGYNKYHVVKEYYFRCVLSAISYACMGHAMYLMTSGEKISRHIIIFYFLQLFLDMSWFLVFYIMSMLRTSAIISALNVLLSVYNFLTWNSMSAVIGACISPFMVVSSLHLLLNYNVISLSKKSEKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5G8</accession>
    <name>Q9J5G8_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV035</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV035</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038998.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486583"/>
    <dbReference type="KEGG" id="vg:1486583"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="135" mass="15571" checksum="10FEBFE56A5B084C" modified="2000-10-01" version="1">MDINIKELEHDKDVINYINKIKDLCSCHTMFPNSINFIMRKLLNLRDTSNIIGMFRLNKINNCIHHIKSGDEIIIYGSYIDSSGLTIRVSTSTSTKFTYIDMLSIIAIKCNTDYLIECITNNDFEVVIFGIRKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5H0</accession>
    <name>Q9J5H0_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ORF FPV032 DNase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FPV032</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">NVSL</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNase II family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038995.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486751"/>
    <dbReference type="KEGG" id="vg:1486751"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004531">
        <property type="term" value="F:deoxyribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004947">
        <property type="entry name" value="DNase_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10858">
        <property type="entry name" value="PTHR10858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03265">
        <property type="entry name" value="DNase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AAF44376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="232" mass="26772" checksum="14C05BB3BA79C73A" modified="2000-10-01" version="1">MAWNSDSVTGFWLIHSVPRFPPSPVLGYNYPYSGYVYGQSMLCINLDYKGGLTALDNTLPVNNPNVYNCSVTNKNLNNLYHLCNDKNYTTLYKNVSRWMESRKGEKFLTFAKSKYFRHDIMSAWIGPTLESDLLSETWQRRGESMITNCSSKYHVHNIKSINVNGTSFINYYDHSKWIVSLYDKKGWVCIGDINRSPTQRHRGGGYACTRNGYLFKLLKETVIEYEGCVINM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5H2</accession>
    <name>V029_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative peptidyl-tRNA hydrolase</fullName>
            <shortName>PTH</shortName>
            <ecNumber>3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV029</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction>
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PTH2 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038992.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5H2"/>
    <dbReference type="GeneID" id="1486748"/>
    <dbReference type="KEGG" id="vg:1486748"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PTHR12649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="SSF102462"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00283">
        <property type="entry name" value="arch_pth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000120286" description="Putative peptidyl-tRNA hydrolase">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="124" mass="14325" checksum="6BCF767A560AE47C" modified="2000-10-01" version="1">MANVFDNSSYRDMLKMVFVIRDDLKMTKGEIVSQCCHGAISAYEKSKKYSPDYLKRWLKNGQVKETVKVDNENEMMDIRENATAIGVNYYIVQNDKRQKCNTVLVIGPAPNYMFESLTRSLKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5H3</accession>
    <name>Q9J5H3_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV028</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV028</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038991.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486747"/>
    <dbReference type="KEGG" id="vg:1486747"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="180" mass="21289" checksum="FF7FD0ECB3F8DBBF" modified="2000-10-01" version="1">MEENILVKTFDELYKNRFVDEIYHNDKLITFNKKKGKGNNLCYSIIEYINPIYDSCYSVAKVVYITNGVMYATLNYMGKPVENRELVPINKLLSDSEILSMGVNAKDLSTKHYEYKYKVSTNHDKKRDSSLVNIIKDDSLLEKLDYFLEGYGDWKITTIRPRQFPNKFCKYRISKYYFSL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5H5</accession>
    <name>V026_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV026</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV026</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038989.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5H5"/>
    <dbReference type="GeneID" id="1486745"/>
    <dbReference type="KEGG" id="vg:1486745"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018272">
        <property type="entry name" value="PRANC_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09372">
        <property type="entry name" value="PRANC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067108" description="Putative ankyrin repeat protein FPV026">
        <location>
            <begin position="1"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="101"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="135"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="168"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="201"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 6">
        <location>
            <begin position="234"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="409"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00080"/>
        </source>
    </evidence>
    <sequence length="436" mass="50514" checksum="5EA094C1E79E76C0" modified="2000-10-01" version="1">MWLFPERVYYLKNENLLISFYIECYLTITTMFLDDDTPHEESTVQPYSINLVRRLMEGNTKDEGIRVLRMAIKFERIDIIKILLEYGVNVNENEYYEEELTCYSVLHFAVDIGNKDIVSILLYAGADVNNTRCYLRNTPLHLAIQQKNTDIAKLLLDSGADQNITNENGNIPIQIAVTYNDEKMVNILLQYSPNLEIADYNGRTVLHNAVLDKNINIVSLLLENGALVDSKCIEGYTILLSSVNRTDPFIIKMLLHRGANPFFLNIKLNHIPLTWYCYCHGNSLSMTVKDLISSAVMISHIRDKVKLTPGFKINEDFTNSIYRFNYYKNLCEEEIRNMKIRRAGYKLTVFDFIKAGKQDDHNTLARCIELLLVGVNKNEFQIYGDIIDQYIKIGLYRKEQLDRVVNSLTSTITNLPYEVIYIIVEKMTNKELCEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5H6</accession>
    <name>Q9J5H6_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV025</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV025</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038988.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486744"/>
    <dbReference type="KEGG" id="vg:1486744"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="203" mass="22928" checksum="9D6EB336F1830879" modified="2000-10-01" version="1">MATTIQKELEKIVVKEKQNKKDAILMGLEVEVPWDYCNWASISFYDIRLEKGISDLESIAVKYMTGCDIPPHVTLGIANKDQESNFKRFKELTKNIDLTSLSFTCKEVICFPQSRASKELGANGRAVVMKLEASDDVKALRNVLFNVVPTPREIFGSVLSDPVWCPHVTIGYVSADDEDNKNRFIELAEAFRGSKIKVTGWYE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5I0</accession>
    <name>V021_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>G-protein coupled receptor homolog FPV021</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV021</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Host cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038984.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5I0"/>
    <dbReference type="GeneID" id="1486740"/>
    <dbReference type="KEGG" id="vg:1486740"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000248">
        <property type="entry name" value="ATII_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000826">
        <property type="entry name" value="Formyl_rcpt-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24225">
        <property type="entry name" value="PTHR24225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00241">
        <property type="entry name" value="ANGIOTENSINR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0297">G-protein coupled receptor</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-1032">Host cell membrane</keyword>
    <keyword id="KW-1043">Host membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0675">Receptor</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0807">Transducer</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000070248" description="G-protein coupled receptor homolog FPV021">
        <location>
            <begin position="1"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="topological domain" description="Extracellular" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=1" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=2" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="topological domain" description="Extracellular" evidence="1">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=3" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=4" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="topological domain" description="Extracellular" evidence="1">
        <location>
            <begin position="155"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=5" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="210"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=6" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="topological domain" description="Extracellular" evidence="1">
        <location>
            <begin position="244"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=7" evidence="1">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="282"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine; by host" evidence="1">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="89"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="320" mass="37809" checksum="5F082B9A1C616958" modified="2000-10-01" version="1">MDTDYGTVHTQQSVKGNTLILLIYFISFIVGFPGNCTVIWFTGYRWKKSVTTIWFLNLAIADTLFVIFIPFEITYILMGHYWPFGLFVCRIGSLMFNTGMYASIFFLTFISIDRYCLAFRRDICNKYRYRINIMVMIIISWIISILLSTPYMYFKNTNEKYRNNRDCLEDYHSDNNTYLLRRVVFCISLVMRYLVPSVVMLFCYCLLLFKHSLFLSKGQTYTIVIMITSFMVLWTPYNILYFIDVIGSHYYNADTIIDAAPISISLIFLSSSINPMIYMLVGRYVSFENYSMRESLKLILSEERDNQTNHENEIKMENIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5I2</accession>
    <name>Q9J5I2_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein FPV019</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV019</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038982.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486738"/>
    <dbReference type="KEGG" id="vg:1486738"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="104" mass="12459" checksum="17A3287AA83AA06C" modified="2000-10-01" version="1">MEYSIKGKRTYKRRKRRNTCCKIFIKYLNIIGLHIYNAYENNKDTIFYYLTKCKTSICKYRSHINGKCLTNIMQKITHMIVKSVINTGMTSFIQNPYKQKLTDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5I4</accession>
    <name>Q9J5I4_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV017 V-type Ig domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV017</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038980.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486736"/>
    <dbReference type="KEGG" id="vg:1486736"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="245" mass="28434" checksum="527C6E1F3D39D317" modified="2000-10-01" version="1">MYGKIYSFSLFLLTTFIQCNSYTMVVHNDVRVNLTCILPPDIHATKLVVIKGNLKNNTFKVTIDIHNAGEDSICYCNDPDKEYNVELPRRSSRNDEGRYRCIFYYNKTESYRHIIELRVMPRVDAYAVDDVGRGLIDFIINRTRTMEDSEVKVDARAGGVVLSEDTQLVEYKKYHECEKVVANKNYTDFTTEVIFTVSYKGLSRDYIASIISCDDKEPRQDLSVVLISGSFLEYGEKSRYKRWLE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2021-02-10" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5J0</accession>
    <name>V011_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Soluble NSF attachment protein homolog FPV011</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV011</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNAP family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038974.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5J0"/>
    <dbReference type="GeneID" id="1486730"/>
    <dbReference type="KEGG" id="vg:1486730"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="CDD" id="cd15832">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="PTHR13768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00448">
        <property type="entry name" value="NSFATTACHMNT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0653">Protein transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000219077" description="Soluble NSF attachment protein homolog FPV011">
        <location>
            <begin position="1"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="278" mass="31577" checksum="2060D42A1573E65A" modified="2000-10-01" version="1">MQKIKLKVSPFFKNLFGPPIEIEEAAGMVSHAANLFASVQLWECAGKAFFKSGDMLLQKNKNSIAAASSFVDAANAFKKIDSYEAINCLSKAIEVYTCLGKFYTVARCHMNIAAIYENDILELDKAIFHYENASGYYGGEGYNKLSDDCMLLIARLSIQKEDFDRAGKIFEQVGYNRMNTMLSKYESRHQLLYAIMCYLCSDVSRAKRSLDKYKDIFPAFKDFKECKFIEKILAACETKNIETFTSAIEEYDHGNTIDEALMSMLLTIRKATFEDEVE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-01-11" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>O72904</accession>
    <name>NPH2_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>RNA helicase NPH-II</fullName>
            <ecNumber>3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Nucleoside triphosphatase II</fullName>
            <shortName>NTPase II</shortName>
        </alternativeName>
        <alternativeName>
            <fullName>Nucleoside triphosphate phosphohydrolase II</fullName>
            <shortName>NPH II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">NPH2</name>
        <name type="ordered locus">FPV082</name>
        <name type="ORF">FPI8R</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1992" name="Virus Res." volume="24" first="161" last="172">
            <title>Gene translocations in poxviruses: the fowlpox virus thymidine kinase gene is flanked by 15 bp direct repeats and occupies the locus which in vaccinia virus is occupied by the ribonucleotide reductase large subunit gene.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Boursnell M.E.G."/>
                <person name="Skinner M.A."/>
            </authorList>
            <dbReference type="PubMed" id="1326827"/>
            <dbReference type="DOI" id="10.1016/0168-1702(92)90004-S"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase. Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm. Required for replication and propagation of viral particles.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text>Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location>Virion</location>
        </subcellularLocation>
        <text evidence="1">Localizes to the virion core.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DEAD box helicase family. DEAH subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13"/>
    <dbReference type="EMBL" id="AJ223385">
        <property type="protein sequence ID" value="CAA11299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="G48563">
        <property type="entry name" value="G48563"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039045.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="O72904"/>
    <dbReference type="PRIDE" id="O72904"/>
    <dbReference type="GeneID" id="1486630"/>
    <dbReference type="KEGG" id="vg:1486630"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021892">
        <property type="entry name" value="NPH-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12011">
        <property type="entry name" value="NPH-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0347">Helicase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000055187" description="RNA helicase NPH-II">
        <location>
            <begin position="1"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="181"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="386"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DEXH box">
        <location>
            <begin position="303"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="194"/>
            <end position="201"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="682" mass="79808" checksum="F394E69FD9745652" modified="1998-08-01" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2000-05-30" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>O72907</accession>
    <name>NTP1_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Nucleoside triphosphatase I</fullName>
            <ecNumber>3.6.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>NPH-I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>Nucleoside triphosphate phosphohydrolase I</fullName>
            <shortName>NPH I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">NPH1</name>
        <name type="ordered locus">FPV052</name>
        <name type="ORF">FP-D11</name>
        <name type="ORF">FPD11</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="submission" date="1998-05" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Skinner M.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1990" name="J. Gen. Virol." volume="71" first="2873" last="2881">
            <title>Analysis of the fowlpox virus genome region corresponding to the vaccinia virus D6 to A1 region: location of, and variation in, non-essential genes in poxviruses.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Britton B.S."/>
                <person name="Mason C."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2177083"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent ATPase required for providing the needed energy to achieve the termination of early transcripts. Acts in concert with the RAP94 subunit of the virion RNA polymerase and the capping enzyme/VTF to catalyze release of UUUUUNU-containing nascent RNA from the elongation complex. NPH-I must bind ssDNA in order to exhibit ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="EC" id="3.6.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Interacts (via C-terminus) with RAP94 (via N-terminus). Interacts with the cap-specific mRNA (nucleoside-2'-O-)-methyltransferase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Virion core enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the helicase family. NPH I subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.15"/>
    <dbReference type="EMBL" id="AJ005163">
        <property type="protein sequence ID" value="CAA06401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S42251">
        <property type="entry name" value="S42251"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039015.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="O72907"/>
    <dbReference type="GeneID" id="1486600"/>
    <dbReference type="KEGG" id="vg:1486600"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013676">
        <property type="entry name" value="NPHI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08469">
        <property type="entry name" value="NPHI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099094" description="Nucleoside triphosphatase I">
        <location>
            <begin position="1"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="43"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="358"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Binding to the cap-specific mRNA (nucleoside-2'-O-)-methyltransferase" evidence="1">
        <location>
            <begin position="459"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DEXH box">
        <location>
            <begin position="142"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="56"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="637" mass="73774" checksum="9F838D2E0519F0D8" modified="1998-08-01" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2021-09-29" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>O72908</accession>
    <name>MCES_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>mRNA-capping enzyme small subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>mRNA (guanine-N(7))-methyltransferase</fullName>
            <ecNumber>2.1.1.56</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName>mRNA cap methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV051</name>
        <name type="ORF">FP-D12</name>
        <name type="ORF">FPD12</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="submission" date="1998-05" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Skinner M.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1990" name="J. Gen. Virol." volume="71" first="2873" last="2881">
            <title>Analysis of the fowlpox virus genome region corresponding to the vaccinia virus D6 to A1 region: location of, and variation in, non-essential genes in poxviruses.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Britton B.S."/>
                <person name="Mason C."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2177083"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text>Catalyzes the last reaction in the mRNA cap formation pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a 5'-end (5'-triphosphoguanosine)-(ribonucleoside) in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:67008"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.1.1.56"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text>Heterodimer of a large and a small subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text>All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.56"/>
    <dbReference type="EMBL" id="AJ005163">
        <property type="protein sequence ID" value="CAA06402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S42252">
        <property type="entry name" value="S42252"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039014.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="O72908"/>
    <dbReference type="PRIDE" id="O72908"/>
    <dbReference type="GeneID" id="1486599"/>
    <dbReference type="KEGG" id="vg:1486599"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005009">
        <property type="entry name" value="Poxvirus_mRNA-cap_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043096">
        <property type="entry name" value="Poxvirus_mRNA-cap_ssu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03341">
        <property type="entry name" value="Pox_mRNA-cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-0506">mRNA capping</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000210139" description="mRNA-capping enzyme small subunit">
        <location>
            <begin position="1"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="289" mass="33867" checksum="ADCEFC32AA71B131" modified="1998-08-01" version="1">MNTDRITAFIKNGISARMPFYDTLPDMDLVFGKNHLPSLEYGANYFLQLSKINDINRLSTEMLSLYTHDLNKESDISKLFEPYNIKTIKSYGRSIQADAVVVDLRPSNSLYKNEHPYYKSNNYLKENNLYICDYTMITFEIYRPIFELSTEKTCIIKVPTLFGKTIVNAVRVYCSLFRYVKLYKLSADSWLKDSAIIVCQQPHAANINKFITYIRKVTKSQTWLDSNNVNFILIHDSVERVFIEKFLSFSYKIYESLYYVHSLLYSSMTSDLQSLDNEYQKKLIKLLRG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>O90760</accession>
    <name>V031_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV031</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">ANK3</name>
        <name type="ordered locus">FPV031</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1998" name="J. Virol." volume="72" first="6742" last="6751">
            <title>Fowlpox virus encodes nonessential homologs of cellular alpha-SNAP, PC-1, and an orphan human homolog of a secreted nematode protein.</title>
            <authorList>
                <person name="Laidlaw S.M."/>
                <person name="Anwar M.A."/>
                <person name="Thomas W."/>
                <person name="Green P."/>
                <person name="Shaw K."/>
                <person name="Skinner M.A."/>
            </authorList>
            <dbReference type="PubMed" id="9658122"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AJ006408">
        <property type="protein sequence ID" value="CAA07013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038994.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="O90760"/>
    <dbReference type="GeneID" id="1486750"/>
    <dbReference type="KEGG" id="vg:1486750"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018272">
        <property type="entry name" value="PRANC_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09372">
        <property type="entry name" value="PRANC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067109" description="Putative ankyrin repeat protein FPV031">
        <location>
            <begin position="1"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="58"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="92"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="125"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="163"/>
            <end position="195"/>
        </location>
    </feature>
    <sequence length="341" mass="39311" checksum="8F55C94BBAE5CC8E" modified="1998-11-01" version="1">MPFLIELLRITGIVTLCPKYRLDRNSLLLVATKRNYIDVVRYLVKKGVDINFQETIRDNLTPLMIASRFNSHQLVELLLNNGAIINQRSLTCGNTALHLAVKNDNRITVDILLFHGANTNITNNDGFTPLHKAVIYNASIDIIKKLLRYKADVNIRDNEEENTGLTPLDIAMSCNNYEIISLLVSHVIRLDYSTCMSNKTKGFDHNKKLVKDNKRLQRIAIHCLKDIEKMKQVSINSRFTLFDLFVNNNVDLLLRCINKDNRFIVNFDKKLTVFNILYTDFIDTFMSRHVLLNKASKVLEDLFLDNDSNTSSWNNLPNEIKDHIFTYINNDELKIMTGSKT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-01-01" modified="2022-02-23" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>P14360</accession>
    <name>V240_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV240</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>BamHI-ORF7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV240</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1025" last="1040">
            <title>Sequence analysis of an 11.2 kilobase, near-terminal, BamHI fragment of fowlpox virus.</title>
            <authorList>
                <person name="Tomley F."/>
                <person name="Binns M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E."/>
            </authorList>
            <dbReference type="PubMed" id="2836548"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="G29963">
        <property type="entry name" value="WMVZF7"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039203.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P14360"/>
    <dbReference type="GeneID" id="1486812"/>
    <dbReference type="KEGG" id="vg:1486812"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018272">
        <property type="entry name" value="PRANC_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09372">
        <property type="entry name" value="PRANC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-0244">Early protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067126" description="Putative ankyrin repeat protein FPV240">
        <location>
            <begin position="1"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="66"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="100"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="133"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="166"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 6">
        <location>
            <begin position="200"/>
            <end position="229"/>
        </location>
    </feature>
    <sequence length="410" mass="46874" checksum="20D576EC48503E5C" modified="1990-01-01" version="1">MDRVELCNAILFGELDVARRLLDSYINPNFTINGYSPIKMAVRLRDVEMIKLLMSYNTYPDYNYPDIESELHEAVEEGDVVKVEELLDSGKFINDVIYKKGNTPLHLATISKNLDMMRLLIARGADTDVPNTDRFTPLHLAVMSKDIKGIELLLDHRACTNIEDCYGCTPLIIAMSKGDTEVCRMLLDSGANIDYFSKRPCVTAMCYAIQNNKIDMVSMFLKRGADSNIVFTVMNEEHTTLEMICNMDTNPESESVDMLIADIALRQYTNTISSDKGFSRNMTVINSKSRLKDVFEKCKIELRRINSESIRTYNILDLCLKPSKNLDENILARHSRKILGLYDNAIFYKYLLKELADTASQRAEAIESAMRVIDEKITGDETKWNWLPHEIKYNILEYIGNKELDIASMK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-01-01" modified="2020-08-12" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>P14362</accession>
    <name>V250_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein FPV250</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>BamHI-ORF4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV250</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1025" last="1040">
            <title>Sequence analysis of an 11.2 kilobase, near-terminal, BamHI fragment of fowlpox virus.</title>
            <authorList>
                <person name="Tomley F."/>
                <person name="Binns M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E."/>
            </authorList>
            <dbReference type="PubMed" id="2836548"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="D29963">
        <property type="entry name" value="WMVZF4"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039213.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486822"/>
    <dbReference type="KEGG" id="vg:1486822"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003360">
        <property type="entry name" value="US22-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02393">
        <property type="entry name" value="US22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0244">Early protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099737" description="Uncharacterized protein FPV250">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <sequence length="140" mass="16508" checksum="0909406BC510C425" modified="1990-01-01" version="1">MDRNINLPEEELKYIKECCEVLYLPQPTRMDIIGVMNDSDISWNENLIILMSEDGKIYVYDDEALYKVADTMEEFSEIGLINLGNEVYHCREDIKPLPEEDRDKDEYIMKIREKARQLIDNSQKDFEAILDSLENKHVSI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-01-01" modified="2020-08-12" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>P14363</accession>
    <name>V249_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein FPV249</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>BamHI-ORF5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV249</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1025" last="1040">
            <title>Sequence analysis of an 11.2 kilobase, near-terminal, BamHI fragment of fowlpox virus.</title>
            <authorList>
                <person name="Tomley F."/>
                <person name="Binns M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E."/>
            </authorList>
            <dbReference type="PubMed" id="2836548"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="E29963">
        <property type="entry name" value="WMVZFF"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039212.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P14363"/>
    <dbReference type="GeneID" id="1486821"/>
    <dbReference type="KEGG" id="vg:1486821"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0244">Early protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099736" description="Uncharacterized protein FPV249">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <sequence length="105" mass="12574" checksum="816F3D04DED47E93" modified="1990-01-01" version="1">MIIRRNNKALGSVMSDFIKTINEEYDSNIKEIKSEIDIKCNSILKELDEKYRQEIKELCMIVDQLKNQYKIIDNIYSRYITEIRIQLLALKEENKCLKEELTKLK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-01-01" modified="2022-02-23" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>P14365</accession>
    <name>V236_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein FPV236</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>BamHI-ORF10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV236</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1025" last="1040">
            <title>Sequence analysis of an 11.2 kilobase, near-terminal, BamHI fragment of fowlpox virus.</title>
            <authorList>
                <person name="Tomley F."/>
                <person name="Binns M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E."/>
            </authorList>
            <dbReference type="PubMed" id="2836548"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="A30087">
        <property type="entry name" value="WMVZFT"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039199.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P14365"/>
    <dbReference type="GeneID" id="1486808"/>
    <dbReference type="KEGG" id="vg:1486808"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017880">
        <property type="entry name" value="KilA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA_N/APSES_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51301">
        <property type="entry name" value="KILA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0244">Early protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099732" description="Uncharacterized protein FPV236">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="KilA-N" evidence="1">
        <location>
            <begin position="26"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00631"/>
        </source>
    </evidence>
    <sequence length="280" mass="33040" checksum="DF5E6B7EB3D00A57" modified="1990-01-01" version="1">MKFKEVRNTIKKMNITDIKICGINEYFMSMKLLDVEVVIMRSNGFVNITRLCNLEGKDFNDWKQLESSRRLLNTLKDNNKLHDPIINIRHTRIKINGEYVSQLLLDYVIPWISPYVATRVSILMRYYRRCVALNIETEKDIDHSQELQNQISKIDEVYDRSIKDISNRFKEIETSYYSKLSTYLLTKAERVLEKDYSMEQDIDNNEDIRTDEMIAAIEAEIEENNRRYLSIISGIRKQHAEDRINISKIMLSGDSFNEIIVKIRDYIETTAKPAVANNYE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-01-01" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>P14370</accession>
    <name>V008_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative C-type lectin protein FPV008/FPV253</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>BamHI-ORF2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV008</name>
    </gene>
    <gene>
        <name type="ordered locus">FPV253</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1025" last="1040">
            <title>Sequence analysis of an 11.2 kilobase, near-terminal, BamHI fragment of fowlpox virus.</title>
            <authorList>
                <person name="Tomley F."/>
                <person name="Binns M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E."/>
            </authorList>
            <dbReference type="PubMed" id="2836548"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="B29963">
        <property type="entry name" value="WMVZF2"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038971.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039216.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P14370"/>
    <dbReference type="PRIDE" id="P14370"/>
    <dbReference type="GeneID" id="1486835"/>
    <dbReference type="GeneID" id="1486836"/>
    <dbReference type="KEGG" id="vg:1486835"/>
    <dbReference type="KEGG" id="vg:1486836"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0430">Lectin</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000046726" description="Putative C-type lectin protein FPV008/FPV253">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="1">
        <location>
            <begin position="49"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="77"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="131"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00040"/>
        </source>
    </evidence>
    <sequence length="167" mass="19869" checksum="C769ECAA8AD238ED" modified="1990-01-01" version="1">MPILLKKQVSEVSCYAITVLGILCLILFTILVVVTCKWYYAFPYFSKVCPDEWIGYNSKCYYFTINETNWNDSKKLCDVMDSSLIRFDNIETLNFVSRYGKGSYWIDINQNRKIPGINFSLYYEQGVNDICLLFDTSNIIEMSCIFHERTICVKEDRYTHWYTEYMR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-01-01" modified="2022-02-23" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>P14372</accession>
    <name>V235_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative protein FPV235</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>BamHI-ORF11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV235</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1025" last="1040">
            <title>Sequence analysis of an 11.2 kilobase, near-terminal, BamHI fragment of fowlpox virus.</title>
            <authorList>
                <person name="Tomley F."/>
                <person name="Binns M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E."/>
            </authorList>
            <dbReference type="PubMed" id="2836548"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="B30087">
        <property type="entry name" value="WMVZEL"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039198.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P14372"/>
    <dbReference type="GeneID" id="1486807"/>
    <dbReference type="KEGG" id="vg:1486807"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000046728" description="Putative protein FPV235">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <sequence length="143" mass="16662" checksum="D421E253A20CB01E" modified="1990-01-01" version="1">MCKKARKRGLLTIAFTILLFVIILVDIDRDRYLVRCGKDWLEFDNLCYFISENKLSWDDSMMVCDNLGGGNNININTNSGLLNTSKDYWIKIVDELDCTNINMCNFLYSNIVGCDICTIEKFYICIKPINKINLFSYFVEYTK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-04-01" modified="2022-02-23" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>P15911</accession>
    <name>L2_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein FPV129</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV129</name>
        <name type="ORF">FP3</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1275" last="1283">
            <title>Comparison of a conserved region in fowlpox virus and vaccinia virus genomes and the translocation of the fowlpox virus thymidine kinase gene.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Tomley F.M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2838574"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-444</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Early protein involved in early virion morphogenesis. Participates in the formation and elongation of crescent-shaped membrane precursors of immature virions in cytoplasmic factories.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Virion membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Host cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">Localizes in cytoplasmic virus factories.</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the early phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the chordopoxvirinae L2 family.</text>
    </comment>
    <dbReference type="EMBL" id="D00320">
        <property type="protein sequence ID" value="BAA00226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="JS0223">
        <property type="entry name" value="WMVZP3"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039092.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P15911"/>
    <dbReference type="GeneID" id="1486677"/>
    <dbReference type="KEGG" id="vg:1486677"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008447">
        <property type="entry name" value="Prot_L2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05803">
        <property type="entry name" value="Chordopox_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0244">Early protein</keyword>
    <keyword id="KW-1035">Host cytoplasm</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099620" description="Protein FPV129">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="96" mass="11250" checksum="C78F9D254FBB90C9" modified="1990-04-01" version="1">MHTFLTARLQAIEDVSNRNLSMLELILTRAIVTHWIILDLVLNLIFDSLITSFVIIYSLYSFVARNNKVLLFLLMSYAIFRFIVMYLLYIVSESID</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1991-08-01" modified="2021-02-10" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>P21968</accession>
    <accession>Q9J5E9</accession>
    <name>UNG_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uracil-DNA glycosylase</fullName>
            <shortName>UDG</shortName>
            <ecNumber>3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">UNG</name>
        <name type="ordered locus">FPV062</name>
        <name type="ORF">FPD4</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1990" name="J. Gen. Virol." volume="71" first="1517" last="1524">
            <title>Nucleotide sequence analysis of a 10.5 kbp HindIII fragment of fowlpox virus: relatedness to the central portion of the vaccinia virus HindIII D region.</title>
            <authorList>
                <person name="Tartaglia J."/>
                <person name="Winslow J."/>
                <person name="Goebel S.J."/>
                <person name="Johnson G.P."/>
                <person name="Taylor J."/>
                <person name="Paoletti E."/>
            </authorList>
            <dbReference type="PubMed" id="2165135"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-1</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Interacts with protein A20. Component of the Uracil-DNA glycosylase(UDG)-A20-polymerase complex; A20 and UDG form a heterodimeric processivity factor that associates with E9 to form the processive polymerase holoenzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27"/>
    <dbReference type="EMBL" id="X17202">
        <property type="protein sequence ID" value="CAA35064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="A35216">
        <property type="entry name" value="A35216"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039025.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P21968"/>
    <dbReference type="GeneID" id="1486610"/>
    <dbReference type="KEGG" id="vg:1486610"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000176177" description="Uracil-DNA glycosylase">
        <location>
            <begin position="1"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA35064." evidence="3" ref="1">
        <original>T</original>
        <variation>A</variation>
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="218" mass="25593" checksum="2355AE81686CD24F" modified="2001-08-29" version="2">MKTLKLNNWPYPIEYHEDWENIINHISDVIEETGPWLLEENTSPSHENIFKQLKQSLKDKRVCIVGIDPYPTDATGVPFESPDFSKKTIKAIAENISRRYNVRLFKNYNFLFVEGVLAWNYYLSCREGETKSHKIFWERLADVFINHIAAYVSVFYFLGKSDFSNFRSILNSPTTVVVGYHPAARNRQFDTDETFEIVNTLLELKNEPRINWVQGFEI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1991-08-01" modified="2022-02-23" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>P21972</accession>
    <name>V061_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative CC-type chemokine FPV061</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV061</name>
        <name type="ORF">FP14</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1990" name="J. Gen. Virol." volume="71" first="1517" last="1524">
            <title>Nucleotide sequence analysis of a 10.5 kbp HindIII fragment of fowlpox virus: relatedness to the central portion of the vaccinia virus HindIII D region.</title>
            <authorList>
                <person name="Tartaglia J."/>
                <person name="Winslow J."/>
                <person name="Goebel S.J."/>
                <person name="Johnson G.P."/>
                <person name="Taylor J."/>
                <person name="Paoletti E."/>
            </authorList>
            <dbReference type="PubMed" id="2165135"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-1</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the intercrine beta (chemokine CC) family. Highly divergent.</text>
    </comment>
    <dbReference type="EMBL" id="X17202">
        <property type="protein sequence ID" value="CAA35065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="B35216">
        <property type="entry name" value="B35216"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039024.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P21972"/>
    <dbReference type="GeneID" id="1486609"/>
    <dbReference type="KEGG" id="vg:1486609"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036048">
        <property type="entry name" value="Interleukin_8-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54117">
        <property type="entry name" value="SSF54117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0202">Cytokine</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000144306" description="Putative CC-type chemokine FPV061">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="129" mass="14110" checksum="E0C25E79875E40DB" modified="1991-08-01" version="1">MQSNISIYVLTVIGSCFYNPFILTYECRDDCCNGRYGPVPAPWKVLNCTKTGPGCPDSGYLLTTSENKTYCITGNETDKGNYPQTIGAIFPNCSGMNVGAGRLITRMLEEYPRGKSPSNNSINNIKISC</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1991-08-01" modified="2020-08-12" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>P21973</accession>
    <accession>Q9J5F0</accession>
    <name>V060_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative CC-type chemokine FPV060</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV060</name>
        <name type="ORF">FP18</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1990" name="J. Gen. Virol." volume="71" first="1517" last="1524">
            <title>Nucleotide sequence analysis of a 10.5 kbp HindIII fragment of fowlpox virus: relatedness to the central portion of the vaccinia virus HindIII D region.</title>
            <authorList>
                <person name="Tartaglia J."/>
                <person name="Winslow J."/>
                <person name="Goebel S.J."/>
                <person name="Johnson G.P."/>
                <person name="Taylor J."/>
                <person name="Paoletti E."/>
            </authorList>
            <dbReference type="PubMed" id="2165135"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-1</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the intercrine beta (chemokine CC) family. Highly divergent.</text>
    </comment>
    <comment type="sequence caution" evidence="1">
        <conflict type="frameshift">
            <sequence resource="EMBL-CDS" id="CAA35066" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="X17202">
        <property type="protein sequence ID" value="CAA35066.1"/>
        <property type="status" value="ALT_FRAME"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="C35216">
        <property type="entry name" value="C35216"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039023.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486608"/>
    <dbReference type="KEGG" id="vg:1486608"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020343">
        <property type="entry name" value="Chemokine_CC_FPV060"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17614">
        <property type="entry name" value="FPV060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0202">Cytokine</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000144305" description="Putative CC-type chemokine FPV060">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="188" mass="20920" checksum="468F10E5F91674B8" modified="2001-08-29" version="2">MYTRYKLSILFFVINFYNILCMPLSCETECCMAGKKYDDAAIDRDLCVLLCNLQYLASSNEGIGEILQCCLSSNYTSKTREDLRNCIAKCPPLPDRGCTGECCDLRENVDSLRANNPLGCCNDYTKVSSSSLNEDDVIDCRKSDASCEDRGYLLVRNNGSAVCIPENSKNDNIGFYFGSECSDLSRKG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1991-08-01" modified="2020-12-02" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>P21975</accession>
    <name>V055_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative Ig-like V-type domain-containing protein FPV055</fullName>
            <shortName>Protein Y</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV055</name>
        <name type="ORF">D8</name>
        <name type="ORF">FP30</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1990" name="J. Gen. Virol." volume="71" first="1517" last="1524">
            <title>Nucleotide sequence analysis of a 10.5 kbp HindIII fragment of fowlpox virus: relatedness to the central portion of the vaccinia virus HindIII D region.</title>
            <authorList>
                <person name="Tartaglia J."/>
                <person name="Winslow J."/>
                <person name="Goebel S.J."/>
                <person name="Johnson G.P."/>
                <person name="Taylor J."/>
                <person name="Paoletti E."/>
            </authorList>
            <dbReference type="PubMed" id="2165135"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-1</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1998" name="Virus Genes" volume="17" first="5" last="9">
            <title>Nucleotide sequence of the 4.3 kbp BamHI-N fragment of fowlpox virus FP9.</title>
            <authorList>
                <person name="Pollitt E."/>
                <person name="Skinner M.A."/>
                <person name="Heaphy S."/>
            </authorList>
            <dbReference type="PubMed" id="9778782"/>
            <dbReference type="DOI" id="10.1023/A:1008045914991"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="X17202">
        <property type="protein sequence ID" value="CAA35071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AJ005163">
        <property type="protein sequence ID" value="CAA06399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="H35216">
        <property type="entry name" value="H35216"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039018.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P21975"/>
    <dbReference type="GeneID" id="1486603"/>
    <dbReference type="KEGG" id="vg:1486603"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013151">
        <property type="entry name" value="Immunoglobulin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00047">
        <property type="entry name" value="ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="SSF48726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0393">Immunoglobulin domain</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000072709" description="Putative Ig-like V-type domain-containing protein FPV055">
        <location>
            <begin position="1"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like V-type 1">
        <location>
            <begin position="25"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like V-type 2">
        <location>
            <begin position="140"/>
            <end position="239"/>
        </location>
    </feature>
    <sequence length="275" mass="30887" checksum="C709787B944BDA53" modified="1991-08-01" version="1">MICKNSIRHKELTLIIFLCFIYLSKTFVEVKAPPYVLVPEGSDINLTCFIKDDQGAGEDKVIVAWQQGDGEVTQGIKTTWDTTRQVGQTMLHISKVSKEAEGSYMCVVWINGDADYKKMNLGVFTVSKKTYMHNEVSITPRRSRVDMSDGRPLKIECAFSTRRIYGRSQVNIKWWKIDGITRKWEQQTSGVNLLLHTYGGIGSLSIPNPTTGESTGKYMCVVTCGDIGNVGFRLVKSLSPLSDTESDHSYTSEEGSHFMERCKVKKSPYGGWIVE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1993-10-01" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>P32817</accession>
    <name>D10_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>mRNA-decapping protein D10</fullName>
            <ecNumber>3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV053</name>
        <name type="ORF">D10</name>
        <name type="ORF">FP-D10</name>
        <name type="ORF">FPD10</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1990" name="J. Gen. Virol." volume="71" first="2873" last="2881">
            <title>Analysis of the fowlpox virus genome region corresponding to the vaccinia virus D6 to A1 region: location of, and variation in, non-essential genes in poxviruses.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Britton B.S."/>
                <person name="Mason C."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2177083"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="1998-05" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Skinner M.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Decapping enzyme required for the removal of the 5'-end m7GpppN cap tethered to viral and host mRNAs to allow their decay in cells. May therefore accelerate viral and cellular mRNA turnover to eliminate competing host mRNAs and allow stage-specific synthesis of viral proteins. Acceleration of the turnover of cellular transcripts may even promote the shutoff of host protein synthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-"/>
    <dbReference type="EMBL" id="AJ005163">
        <property type="protein sequence ID" value="CAA06400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S42250">
        <property type="entry name" value="S42250"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039016.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486601"/>
    <dbReference type="KEGG" id="vg:1486601"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003301">
        <property type="entry name" value="Vaccinia_D10_decapping"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01364">
        <property type="entry name" value="VD10PROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000057095" description="mRNA-decapping protein D10">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="35"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Nudix box">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="225" mass="26445" checksum="C9668C82951A64D7" modified="1993-10-01" version="1">MGEYYKNKLLLRPSVYSDNIQKIKLVAYEYGKLHAKYPLSVIGIMKTIDDKFVLCHRYNSFLFSEIAFTKDKRRKIRLFKKYSKYMSNIERDILSYKLSLPNNYNTNHIDIIFPGGKIKDLESITNCLVREIKEELNIDSSYLAICKNCFVYGSIYDRLIDKDFEVIALYVETDLTSRQILNRFIPNREIKGISFIDARDINKDYLYTNVIKYIINAVRTSASNS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1997-11-01" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>Q67480</accession>
    <accession>Q9J5G0</accession>
    <name>DNLI_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>DNA ligase</fullName>
            <ecNumber evidence="2">6.5.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Polydeoxyribonucleotide synthase [ATP]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">LIG</name>
        <name type="ordered locus">FPV043</name>
        <name type="ORF">A50R</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1994" name="J. Gen. Virol." volume="75" first="2495" last="2498">
            <title>Deletion of fowlpox virus homologues of vaccinia virus genes between the 3 beta-hydroxysteroid dehydrogenase (A44L) and DNA ligase (A50R) genes.</title>
            <authorList>
                <person name="Skinner M.A."/>
                <person name="Moore J.B."/>
                <person name="Binns M.M."/>
                <person name="Smith G.L."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="8077953"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text>DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. It is not essential for viral replication and recombination.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP + diphosphate.</text>
            <dbReference type="EC" id="6.5.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="2"/>
    <dbReference type="EMBL" id="Z29716">
        <property type="protein sequence ID" value="CAA82805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S41974">
        <property type="entry name" value="S41974"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039006.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q67480"/>
    <dbReference type="GeneID" id="1486591"/>
    <dbReference type="KEGG" id="vg:1486591"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="SSF117018"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0233">DNA recombination</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000059591" description="DNA ligase">
        <location>
            <begin position="1"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="2">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA82805." evidence="3" ref="1">
        <original>K</original>
        <variation>N</variation>
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="564" mass="64487" checksum="85B5D829FEE89FA0" modified="2001-08-29" version="2"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2011-07-27" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>Q77NS7</accession>
    <name>Q77NS7_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV203 Tyrosine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV203</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039166.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q77NS7"/>
    <dbReference type="GeneID" id="1486775"/>
    <dbReference type="KEGG" id="vg:1486775"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="285" mass="33338" checksum="C9AA9CC08D520643" modified="2011-07-27" version="1">MDIITNTTMFDIQFNDIPNIPYVDIEKPLLVYSCDSYRLYNAKYDNNPVSLKTFTCPSKNSIRQFIKELDLLRSLQSSEHVIKLYGYILDISVPLCSLVVENNYLTLRNFLDMEKDIDYAKKTRIIIDAAKGLNAMHTSYSTPILHKNLTSESFYMTNNGVLKIGSGAYYNIYKRVNFMAYFDYDMLKDIFSNYTIKSEIYRFGIVIWEIITRKIPFENMDYQGIYNMLIKENKGEYMPLDCPLELQCIVIACRNTNSIFRPSISAIIDFLETFYSNIIKNRNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-07-27" modified="2020-08-12" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>Q77NS8</accession>
    <name>Q77NS8_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV201</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV201</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039164.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486773"/>
    <dbReference type="KEGG" id="vg:1486773"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="283" mass="32418" checksum="3A186482234D9F5F" modified="2011-07-27" version="1">MATVARMYKTINTTGISCVLKSLIPDSYNEEYNIDDLDLLKIKEFIEISMQRCFSIKSVTDSTVLYIENRTNRYSISTSHDKNEPYEENGIIMNNIECYFVACLEGSCTVNVNLGDRQISDNISESSGFLMDVNTDHVIDTKYVGLFITKIKVDAHVFYGQNVIMFPEKNLFSQTNGPNFILYDITVQDRNVLLLITSKYIYNLCDDKYYDIFELKYLVDNCKLPMPLIPLSKYDFTFTDLSVIKSENVKTVLSKVHTSMKSYYNNDTSLPVAVKVIYGTVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-07-27" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>Q77NS9</accession>
    <name>Q77NS9_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyribodipyrimidine photo-lyase</fullName>
            <ecNumber evidence="3">4.1.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">DNA photolyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">FPV158</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">NVSL</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA photolyase class-2 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.3" evidence="3"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039121.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486706"/>
    <dbReference type="KEGG" id="vg:1486706"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008148">
        <property type="entry name" value="DNA_photolyase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032673">
        <property type="entry name" value="DNA_photolyase_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00591">
        <property type="entry name" value="phr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01084">
        <property type="entry name" value="DNA_PHOTOLYASES_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="10">
        <location>
            <begin position="37"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AAF44502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="464" mass="54590" checksum="EB86F7F4CCFE4BF4" modified="2011-07-27" version="1">MISPQSDENIKDVENFEYNKKRNRTLSISKHINKNSKVVLYWMFRDQRVQDNWALIYAQRLALKLKIPLRICFCVVPKFHTTTSRHFMFLISGLKEVAEECKRLCIGFSLIYGVPKVIIPCIVKKYRVGVIITDFFPLRVPERLMKQTVISLPDNIPFIQVDAHNIVPCWEASDKEEYGARTLRKKIFDKLYEYMTEFPVVRKHPYGPFSISIAKPKNISLDKTVLPVKWATPGTKAGIIVLKEFIKNRLPSYDADHNNPTCDALSNLSPWLHFGHVSAQRVALEVLKCIRESKKNVETFIDEIIVRRELSDNFCYYNKHYDSIQSTHSWARKTLEDHINDPRKYIYSIKQLEKAETHDPLWNASQMQMVREGKMHSFLRMYWAKKILEWTRTPEDALSYSIYLNNKYELDGTDPNGYVGCMWSICGLHDRAWKERPIFGKIRYMNYESSKKKFDVAVFIQKYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-07-27" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>Q77NT1</accession>
    <name>Q77NT1_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV087 HT motif gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV087</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="B48563">
        <property type="entry name" value="B48563"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039050.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486635"/>
    <dbReference type="KEGG" id="vg:1486635"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045408">
        <property type="entry name" value="DUF5890"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19240">
        <property type="entry name" value="DUF5890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="91" mass="11164" checksum="6E1B80293225EE90" modified="2011-07-27" version="1">MEFDISSCRMIYSVLEQYHFVTDNRYNNHNQKFRIILYCLKDSTIKKYPYRFVSEIHFVRYIINKFRGKNLYKISIEAIDISKGRQQIIRT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>Q85281</accession>
    <name>J5_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein J5 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>FPV136</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV136</name>
        <name type="ORF">F11</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1987" name="Virology" volume="160" first="203" last="209">
            <title>Similar genetic organization between a region of fowlpox virus DNA and the vaccinia virus HindIII J fragment despite divergent location of the thymidine kinase gene.</title>
            <authorList>
                <person name="Drillien R."/>
                <person name="Spehner D."/>
                <person name="Villeval D."/>
                <person name="Lecocq J.-P."/>
            </authorList>
            <dbReference type="PubMed" id="2820129"/>
            <dbReference type="DOI" id="10.1016/0042-6822(87)90061-4"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>Salisbury</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text>Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry. Also plays a role in cell-cell fusion (syncytium formation).</text>
    </comment>
    <comment type="subunit">
        <text>Part of a stable entry-fusion complex (EFC) which is at least composed of proteins A16, A21, A28, G3, G9, H2, J5, and L5. Formation of the viral membrane is necessary for the assembly of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Virion membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">Component of the mature virion (MV) membrane. The mature virion is located in the cytoplasm of infected cells and is probably released by cell lysis (By similarity).</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the poxviridae A16/G9/J5 family.</text>
    </comment>
    <dbReference type="EMBL" id="M17418">
        <property type="protein sequence ID" value="AAA66424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039099.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486684"/>
    <dbReference type="KEGG" id="vg:1486684"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019031">
        <property type="term" value="C:viral envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055036">
        <property type="term" value="C:virion membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019064">
        <property type="term" value="P:fusion of virus membrane with host plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046718">
        <property type="term" value="P:viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004251">
        <property type="entry name" value="Pox_virus_G9/A16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03003">
        <property type="entry name" value="Pox_G9-A16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1169">Fusion of virus membrane with host cell membrane</keyword>
    <keyword id="KW-1168">Fusion of virus membrane with host membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0735">Signal-anchor</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0261">Viral envelope protein</keyword>
    <keyword id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <keyword id="KW-1160">Virus entry into host cell</keyword>
    <feature type="chain" id="PRO_0000099597" description="Protein J5 homolog">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="topological domain" description="Virion surface" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Signal-anchor" evidence="2">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="137" mass="15605" checksum="F7AF163C7F67318A" modified="1996-11-01" version="1">MDNVINDEAIFKYCESNPKDRDCLCIHPEPTIEKIGEDLLLPYYCWYEPCKRKTAKIPTALRDNMKRCNLIDCSVSLGEINLLDGILKVNNDCLSSHAIYAGYSVKPLEQEIHLPIIDPKYLILGLAILALIVLINW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-10-07" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>Q9ICC1</accession>
    <name>V003_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative C-type lectin protein FPV003/FPV258</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV003</name>
    </gene>
    <gene>
        <name type="ordered locus">FPV258</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="C31685">
        <property type="entry name" value="C31685"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038966.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039221.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9ICC1"/>
    <dbReference type="PRIDE" id="Q9ICC1"/>
    <dbReference type="GeneID" id="1486833"/>
    <dbReference type="GeneID" id="1486834"/>
    <dbReference type="KEGG" id="vg:1486833"/>
    <dbReference type="KEGG" id="vg:1486834"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0430">Lectin</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000046725" description="Putative C-type lectin protein FPV003/FPV258">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin">
        <location>
            <begin position="21"/>
            <end position="122"/>
        </location>
    </feature>
    <sequence length="123" mass="13970" checksum="BFDDCE4357876076" modified="2000-10-01" version="1">MKSLILIAMLLMLDCANSLNCRGPYTSYNNKCIWVNRLDKMHHKKTYSEASTTCLITFPMGTLARRSLIDNEKDMKFISKFGMGQSLWIRDDKKPEVGKCAYTDGKTFGFSPCNATYGFVCID</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>Q9ICF5</accession>
    <name>Q9ICF5_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV005 EFc gene family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">ORF FPV256 EFc gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV005</name>
        <name evidence="1" type="synonym">FPV256</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="E31685">
        <property type="entry name" value="E31685"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038968.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039219.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486830"/>
    <dbReference type="GeneID" id="1486832"/>
    <dbReference type="KEGG" id="vg:1486830"/>
    <dbReference type="KEGG" id="vg:1486832"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="122" mass="13445" checksum="4FB3A5DD56AA64C5" modified="2000-10-01" version="1">MALNLRVRPVEQESGIKVLAAASDPLNYENDHTGDGGFVARAIRNMEFCRARYLCAAAGDTVKIYFLEGEGELIYSVSRVGSPTADSGYVTRGNCVEFETDSSCFITLMCTSSYNTVVYWME</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>Q9ICF7</accession>
    <name>V007_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein FPV007/FPV254</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV007</name>
    </gene>
    <gene>
        <name type="ordered locus">FPV254</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038970.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039217.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486828"/>
    <dbReference type="GeneID" id="1486837"/>
    <dbReference type="KEGG" id="vg:1486828"/>
    <dbReference type="KEGG" id="vg:1486837"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099725" description="Uncharacterized protein FPV007/FPV254">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <sequence length="72" mass="8434" checksum="4E0DD562D55946F0" modified="2000-10-01" version="1">MLYSVFTRIYKIRKNNKTEMILAIYDRNAYIVKKTGIGSILLRDNGTRNTMLNIIYDTSSRNMQMVLRVSVL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J4Z6</accession>
    <name>V244_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV244</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV244</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44588.1"/>
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        </location>
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        <location>
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        </location>
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        <location>
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    </feature>
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        </location>
    </feature>
    <sequence length="668" mass="76201" checksum="F3C5BA076023791B" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J4Z7</accession>
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        </recommendedName>
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    <organism>
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            <taxon>Chitovirales</taxon>
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        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
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            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
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            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
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</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="72" xmlns="http://uniprot.org/uniprot">
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    </organism>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
    <feature type="repeat" description="ANK 10">
        <location>
            <begin position="316"/>
            <end position="345"/>
        </location>
    </feature>
    <sequence length="358" mass="40885" checksum="AB6D88F1FCECCBF9" modified="2000-10-01" version="1">MISFNNNYRKLRKAIINEDIEEIKYIIEKDPNMIVKVDNNNHTLLHIAIMYRKVNAVKVLLDKGDNLVYVINSFPILPPLYCAIIGFCKLTRRNKISNALEKINNHKKIIEALVDKGVELTGLEIALSCKNIWLIKFLIEKGISVEYTGFFPVGVNYNTIDIDICKVLLENKIDINKPVCGETLVRYAIRSSDLNLLKYLISKGADIEKRNKYEQDPNIIEAVEKGNLGIVEYLIDNGISIDTVSIYNHKPAIYYAILAGHYNMVDLLLRRGANPFITCEGNTSLISVATQAKRNRLKLINLLLKYGVRLPGDHDYYIQPILLDYSYETYNIIHILLEHGLRITSNTTLVSTFLIIRV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="76" xmlns="http://uniprot.org/uniprot">
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        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV232</fullName>
        </recommendedName>
    </protein>
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    </gene>
    <organism>
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        <lineage>
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            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
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    <feature type="chain" id="PRO_0000067123" description="Putative ankyrin repeat protein FPV232">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
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            <begin position="36"/>
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    </feature>
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        </location>
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        </location>
    </feature>
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        <location>
            <begin position="270"/>
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        </location>
    </feature>
    <feature type="repeat" description="ANK 9">
        <location>
            <begin position="301"/>
            <end position="332"/>
        </location>
    </feature>
    <sequence length="482" mass="55457" checksum="F34131B6FAD31BBB" modified="2000-10-01" version="1">MLKLYISMFLDSTEHILKEINRLQHKEQRTNGISCIPLIPLHQAVEARNLEVVEALLERGHNVNETDHRYLTPLHIICSHPNKIGMKEVIAEKTKRDLSSYEERAISEACYNNDINIFKMLLLNDGNRTIDDVQLCTIDYDDSIDTKIIKLLLAYGADTKIKTEDKLKTALHYASTNKNYKLAEYLLIYGAEVNSPDIGNNSPMHEAVRHRNEDVVKILLQYGSNTDHMNSCGTTPLHISVGRVLNRNNYSILKILLEHGTSVNIQSSILGFTALHLSIHSEDKLNLLLEYGADPNILNFEKETPLSMAVKVTRYDINIYNRLIYNICLRAFKYPFIKTTEGYIKNMTCINGYPKCKSIKDACEYEIKNLESIKLSPRFSMADFLKDDNSLMMDKIINNDLIDYYYSFMDSFPIYGNIVKKSIDTAKDRYLLIQGAIRSMDNITFPSQRVSWYNMPLEIKHDIMYLLDDKSLCNLIVAEYDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J510</accession>
    <name>Q9J510_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV225 vaccinia B20R homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV225</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039188.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486797"/>
    <dbReference type="KEGG" id="vg:1486797"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018272">
        <property type="entry name" value="PRANC_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09372">
        <property type="entry name" value="PRANC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="SSF81383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRANC" evidence="1">
        <location>
            <begin position="8"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="104" mass="12810" checksum="3C7C1CE226A3D300" modified="2000-10-01" version="1">MKYVNFINAYSVYDIYINKNKIDINIPLHINYDLKYKEIKNEFPIYRDMIEKKIRYILDKPNLVYKVINCMSEYMDSTYWMFLPTEIKFKVLSYLSSKDLYFII</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J511</accession>
    <name>V224_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV224</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV224</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039187.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J511"/>
    <dbReference type="GeneID" id="1486796"/>
    <dbReference type="KEGG" id="vg:1486796"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067118" description="Putative ankyrin repeat protein FPV224">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="9"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="42"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="94"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <sequence length="146" mass="16759" checksum="9B1064458E4290B2" modified="2000-10-01" version="1">MNINATDNSLSTPLHHAINLLKTDIVSLLMQYKADASIRDSKGITPFCYAMYLGYYGVNKDILNIITRYNSINGTTRDINDVYTILLNNKKKNYVFVNLHDAARLGYVYILKKIIYNGKNINRIDEYYYSALHYAVKSSNLKAVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J514</accession>
    <name>Q9J514_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV221 vaccinia A47L homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV221</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039184.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486793"/>
    <dbReference type="KEGG" id="vg:1486793"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="183" mass="22112" checksum="7D17A98EC2BB2DCA" modified="2000-10-01" version="1">MGNNNTHGSKKNRLSMIYSKKRITSFIRKHHNYLMRVFDYLSDNGKVVMIDCMGHWLYNKWDYEPNMFLKCISERSDIESIYRELAKKTLEDAKNYHNIFPRTVRDNFSISNKLKTVMDNNDILIKKYNSVNYYIKKEIIDTIVNEFKIRRTYEPYLFLQTLERQLRGSNDYFYNDILQAITI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J515</accession>
    <name>V220_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein FPV220</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV220</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039183.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486792"/>
    <dbReference type="KEGG" id="vg:1486792"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099731" description="Uncharacterized protein FPV220">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <sequence length="117" mass="13519" checksum="5DA7301BBC8D29FA" modified="2000-10-01" version="1">MIYTEFTILYKSSLPKYLRIMYFTSIGIFFHKLSIVSLEIVSSKTVNDLEIKLSLSFAVYTAFIIISLYMINSGNVTLLYNLSNIFDSILFRYISNRLLLPIFTSSIFNISFSHSNL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J516</accession>
    <name>V219_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV219</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV219</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039182.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J516"/>
    <dbReference type="GeneID" id="1486791"/>
    <dbReference type="KEGG" id="vg:1486791"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001995">
        <property type="entry name" value="Peptidase_A2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018272">
        <property type="entry name" value="PRANC_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09372">
        <property type="entry name" value="PRANC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067115" description="Putative ankyrin repeat protein FPV219">
        <location>
            <begin position="1"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="66"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="101"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="132"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="165"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 6">
        <location>
            <begin position="196"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 7">
        <location>
            <begin position="229"/>
            <end position="258"/>
        </location>
    </feature>
    <sequence length="434" mass="49245" checksum="917BBCA3D6F7AB71" modified="2000-10-01" version="1">MKLIEAIDNNNLKEVIRIIRSDNINLESINDEDDLSPLHHAVSRGYKEIVISMLEHGADVNLCNDEVCSPLHIAIKNDNVEMVQLLIDNGADTDCCNNTIHGTPLQCAILNENYRITDALLESGADTHEIYTKNHPIIEAIKLDNLPLVRLLLRHGADVNTFDPLYGYPIHLAIRYGNIDIIKELLYHGVIESYSLYPSLLHQSIMCNNKEVVLLLISMGFDVNAKDNEGNTPMHLAVQKNLVGIVKILLDKGADTSIINNLSVTCLRSCYVYGNNSTEILQLLISRIVINKYANIPCRSIAGMNYNWSLIESNQKTNSYKLECEKEILKMLDVKIGSRSLFDIYLNKIESNMLLRLYNKVTLPEFIIYKDIIINAVYTAKERESLISKSFTVLEDTISNDTIDNLWKNIPIEVKYMILRYLGKDDLYNIVNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J518</accession>
    <name>Q9J518_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV217</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV217</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039180.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486789"/>
    <dbReference type="KEGG" id="vg:1486789"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020387">
        <property type="entry name" value="AcMNPV_Orf112"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10860">
        <property type="entry name" value="DUF2661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="328" mass="39244" checksum="B06E855815279225" modified="2000-10-01" version="1">MKLVYVWYHDSVFVPDSLYYPFLSNFRFNSKYRSCHVFYYINNTDNLRIPENEYNQDFIDFKTVFPEDMATLTVLPNKAQKIDFMKLSILFKGHRILNTKSDILLLDFDCHIKTIGKMIYNVEPFYCKKTKYLYVGGQNDEQDSYIENYATRIDEVGSRRLYDIFTRLDFHPGKSKTNSYVYMIYVSMIIEYFKVYHNYIFPTLCENVYLESSVDMSYSRGSTWKIDISNLDDDSLWIIKYSKPFNKAIKDEIQDCIHNKNFSVFYTIVLKELNLPFDKDIFWLNDKQRNGTLKEYVHENIKDSSGNTFISIIDRAINFQKSYIKYQI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J519</accession>
    <name>V216_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV216</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV216</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039179.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J519"/>
    <dbReference type="GeneID" id="1486788"/>
    <dbReference type="KEGG" id="vg:1486788"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067113" description="Putative ankyrin repeat protein FPV216">
        <location>
            <begin position="1"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="107"/>
            <end position="136"/>
        </location>
    </feature>
    <sequence length="296" mass="34298" checksum="C998B1BEAA694637" modified="2000-10-01" version="1">MSITSIINNLIDIITLYIRIFYVIYYIAIKSKNQICIANILYTSIKFYYTDIIDAVLKRGIDPNIPFPLSENSYVNPLIYAIECDNHDAILSLIRYGADVNTYSNYLVITPLYISVLHGCPKCVEILLYYGANINIVTYKMVTPIELASRICYNNLAFMVCDRTITNIPKKITYNFEIMKILVSHFILQASNDRLNNRHNKYFSEGYNKNKMLVSTSIILTYFKKQCIEDIDIMKNIKLGDDSFLDILVERNTMKLSTYISNQDILDIPKTVKVYNTRINMLLDEAIIYNNINIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J522</accession>
    <name>Q9J522_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV213</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV213</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039176.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486785"/>
    <dbReference type="KEGG" id="vg:1486785"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="162" mass="18505" checksum="B181627F29440D65" modified="2000-10-01" version="1">MERVKKCFSNIIFFSKDVDTSMFSPNIVYSGLLDSYNFSFVDALLAVNLSIGIVRRRETLCSKCTNICILNNQVKLLLEFGYRDDKDIIKKGSVSIGLLNMDSRVNITTLFPPCCNFMDAKVLNFNLLFPECDCFFVDVKMNIAEESNFIPRYLFVSPLQDS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J523</accession>
    <name>V212_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Probable serine/threonine-protein kinase FPV212</fullName>
            <ecNumber>2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV212</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction>
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Poxviruses subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039175.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J523"/>
    <dbReference type="PRIDE" id="Q9J523"/>
    <dbReference type="GeneID" id="1486784"/>
    <dbReference type="KEGG" id="vg:1486784"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000086787" description="Probable serine/threonine-protein kinase FPV212">
        <location>
            <begin position="1"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1 2">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="31"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10027"/>
        </source>
    </evidence>
    <sequence length="303" mass="34775" checksum="4B1BFD17C5220716" modified="2000-10-01" version="1">MPQNKVLSFPLPEGTLLEDITKNKWILGKQLGSGGFGLVYQVSCKSKEIDCVAKIELKESGGLFCEINFYNRVMKNKTSLDTWMKEQKIDYIGIPSFHGFGITIYKNVEYRFAIIQRLGRDLENILSEKEKFNITVIKKLAIKILDILKFIHSKEFSHGDIKAGNILFGKDDDKVYLVDYGLATKYSSNGKHKEYTINPKNRHNGTMAFTSIDAHKGVTVSRRGDLESLGFCMLKWYSGKLPWEKYEKEPENVQGMKEAFVNNISKKTIPFKNAGIIYNYIKVVTKLEYEEAPNYESLKQMFL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-10-07" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J524</accession>
    <name>V211_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Probable growth factor FPV211</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV211</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039174.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J524"/>
    <dbReference type="GeneID" id="1486783"/>
    <dbReference type="KEGG" id="vg:1486783"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF-like_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0245">EGF-like domain</keyword>
    <keyword id="KW-0339">Growth factor</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0964">Secreted</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000007606" description="Probable growth factor FPV211">
        <location>
            <begin position="49"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="80"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="84"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <sequence length="125" mass="14559" checksum="A0C676CABCA7EB28" modified="2000-10-01" version="1" precursor="true">MKEPLIEVKREYNLIKTLTGKKFVVSTSIVVVLLIINMIFYGIRIHELAVIRRNSETHISSFNYKGQAQAQNKRVKNTRLFEKCKSKFNNFCIYGECMNIINLDKKFCICNKGYTGNRCDIVSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J526</accession>
    <name>Q9J526_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV209 HT motif gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV209</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039172.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486781"/>
    <dbReference type="KEGG" id="vg:1486781"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045408">
        <property type="entry name" value="DUF5890"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19240">
        <property type="entry name" value="DUF5890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="130" mass="15763" checksum="D102E323AAC4318F" modified="2000-10-01" version="1">MASTKDDITGRFLSENISKEEFFWKHRGLDTIKTFFINEKEDLKRVFSEFHRITKHRFCSPDQRFQVGTYSSGKSYIFECYIREVDYVHGFNSYNIDNIFMIKIMPIKTMNPKEIRSLVIRKYKKLKYYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J527</accession>
    <name>Q9J527_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV208</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV208</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039171.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486780"/>
    <dbReference type="KEGG" id="vg:1486780"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="67" mass="8062" checksum="9AE409A2B9F10433" modified="2000-10-01" version="1">MKRSIKSPDFIIWINGQRNIVNTLRFEEPNVCIKNTLQLVSSRFYKNIRYRTMGRCFTQIFTYSNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J528</accession>
    <name>Q9J528_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV207</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV207</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039170.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486779"/>
    <dbReference type="KEGG" id="vg:1486779"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="100" mass="11576" checksum="2068F328CF9A1235" modified="2000-10-01" version="1">MISLPSSCQNIINTVINGKCFFGRCSNKRLKMTVPMTSSELAYIQEWMLEKHDLFIEFPIDLITVEHIMMHLAVDVTTIKRKKSDITAYRTRLKDVPEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J530</accession>
    <name>Q9J530_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein FPV205</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV205</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039168.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486777"/>
    <dbReference type="KEGG" id="vg:1486777"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="218" mass="25379" checksum="EC8DC533D099FD74" modified="2000-10-01" version="1">MNRVIRILVILSNVVHVYPCKRSVSIEQSEANIILCPSTSIKCVKWMYVEKKEPKSQIYKTLGIMVFPDSYHIKEPNYLSNLTLDKITLKRWSTGDVYHVSIGIKKKCMGSVIESIFVDDSYITRRDNYNSTELYNNTTNIVLVHFLNNYQLYTLVLSSICVVIIIIIVCYISYKHKYINKKIKTISNSEKFILINVHPDREPLITHIDESEYESDDN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J531</accession>
    <accession>O36447</accession>
    <name>V204_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized serpin-like protein FPV204</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV204</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1997" name="Virology" volume="235" first="367" last="376">
            <title>Field and vaccine strains of fowlpox virus carry integrated sequences from the avian retrovirus, reticuloendotheliosis virus.</title>
            <authorList>
                <person name="Hertig C.H."/>
                <person name="Coupar B.E.H."/>
                <person name="Gould A.R."/>
                <person name="Boyle D.B."/>
            </authorList>
            <dbReference type="PubMed" id="9281517"/>
            <dbReference type="DOI" id="10.1006/viro.1997.8691"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-175</scope>
        <source>
            <strain>Mild vaccine</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the serpin family. Poxviruses subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF006064">
        <property type="protein sequence ID" value="AAC58237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039167.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J531"/>
    <dbReference type="GeneID" id="1486776"/>
    <dbReference type="KEGG" id="vg:1486776"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023795">
        <property type="entry name" value="Serpin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="PTHR11461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="SSF56574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00284">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0646">Protease inhibitor</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="chain" id="PRO_0000094157" description="Uncharacterized serpin-like protein FPV204">
        <location>
            <begin position="1"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="342" mass="39624" checksum="024593A94C90BA95" modified="2000-10-01" version="1">MFAISVLKELYDSGEPLLFSPRGLHKILCNIRHGCNGNTKNQLDNLLEETIYDYGEDQALKHIITNISVLLIKRCYNINEKFIKDSNTIYNTDVLEFYNVRQIPRIMNKWIRSRSNNKITDIGCHIYDNTKSIIAEAMFFTMKHESIFGSTRKDTITFYKYDGTSLPVEAIHADPYYYPYRYFDDIKCSVLQLWKLGYAFNMFIILPDDEKGLDNLVDNITGDVFSKIMTEQMDYKRLELRMPVFSISQETNFCMPIFNLGCHSMFIDGDFSGISEVSDFQLSGIIQKNIIEVQYDKVKTTKPLNVRCSSFYVNKPFIFIVTDVGNYDTIPILLGIYQGSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J532</accession>
    <name>Q9J532_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV202</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV202</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039165.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486774"/>
    <dbReference type="KEGG" id="vg:1486774"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="100" mass="12114" checksum="716315F5DB57F5BA" modified="2000-10-01" version="1">MLAFNKHFLLWFMSLLLMPIPRNDISEIYQVQWRLRQASMITEANMAVSEPALFPPELPPHFLYCYCSVNHLNGDRKRRIIVVVRFHTRMNFREYRFNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J533</accession>
    <name>Q9J533_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV200 V-type Ig domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV200</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039163.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486772"/>
    <dbReference type="KEGG" id="vg:1486772"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07686">
        <property type="entry name" value="V-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="SSF48726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="48"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="265" mass="30700" checksum="AF3EB3E1A84C8DF0" modified="2000-10-01" version="1">MIMKYTSSKFIFSLLKIHYNMKFIIILLSILQYVYSKDDYYDVVSHVGDSVILNCNDYPNTSNVDSVIWFKYSDPVNKYLSISTINGTQYYKNDHKIFTRTSVDLKLSSLTITSASIENHGCYGCKFKSGICNRERKTCLGILDSVYLSWISFMYTTRVRCYIVSAKKDLSINWMVNGVITEGMSFNEISYDDSYLSGCFMIELKIINSFSDKVISPICRVNFGSKGYKEYRINLTNTLPDTLYDKYSNPIRYYNPSNSRITKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J534</accession>
    <name>Q9J534_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV199 V-type Ig domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV199</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039162.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486771"/>
    <dbReference type="KEGG" id="vg:1486771"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013151">
        <property type="entry name" value="Immunoglobulin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00047">
        <property type="entry name" value="ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="SSF48726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IG" evidence="1">
        <location>
            <begin position="17"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="219" mass="24951" checksum="EB806F7C60F5EE71" modified="2000-10-01" version="1">MHISSFYILSIICCTSSANIIADIGSSVVVDCKIPNNYSVDTVILKQTSSGKTNKITVPNEYITGNTCNTGYRTYGFTINNVTKNDEGRYRCSFYLSSVQIYETKLTMYVIPAIDAYTLDARDNKMMYACNRSRSRLYDDDINMDIIIGGVYISGEENVHTFDTDHSLHIYTFGDKNYPDISKQMTCLLTFKGVKKTKRITIYDYSWESLINDNEIYVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J536</accession>
    <name>Q9J536_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV197 Virion assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV197</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039160.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486769"/>
    <dbReference type="KEGG" id="vg:1486769"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006758">
        <property type="entry name" value="A32L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04665">
        <property type="entry name" value="Pox_A32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="301" mass="34619" checksum="E27E532B1177A9E3" modified="2000-10-01" version="1">MDIVREVKFNRNSLLNDYFRMVILGGSGSGKTTFLLSLFKTFITKYKHIFLFTPILNPSYNYYVWPDHIYKITTAEELEYSLSKMKQDLVNLGKRGSINHKFLVILDDLGDMQLKSKILSWLVNTGRHIRMSIVMLCQTYRHVPSNCRSSITHLCCCNVSDADIENITRSMSLVATKQIIKALSVMRAASRGKKVYIIENTVFANKDIRICYDTADKSVIEQKPDTAILLSQFSHMKDQLHTILSDDNKDTDYFKDLSKLNSINDDRDKKDCIYSPEKEASSNMKLLKSYSKQESLQELAC</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-12-02" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J538</accession>
    <name>V195_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein FPV195</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV195</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the poxviruses A31 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039158.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486767"/>
    <dbReference type="KEGG" id="vg:1486767"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008786">
        <property type="entry name" value="Poxvirus_A31"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05771">
        <property type="entry name" value="Pox_A31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099312" description="Protein FPV195">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="113" mass="13609" checksum="6973B069675B3328" modified="2000-10-01" version="1">MEIFELISENEKYFNGIPIILPKKKKTYVYKNITFIFYIPSDNKIEQYIQRSELHYSDFIVYGKVIIDDVEMLLLYVNFEYYGISIDGKTKYLGKSIKDLKIRGTKRWKDFTH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-12-02" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J539</accession>
    <name>A30_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein A30 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV194</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the association between the dense viroplasm and the viral membranes to form the mature virion (MV).</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with protein G7; the interaction stabilizes both proteins.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Phosphorylated by viral F10 kinase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae A30 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039157.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486766"/>
    <dbReference type="KEGG" id="vg:1486766"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009257">
        <property type="entry name" value="Chordopox_A30L"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06015">
        <property type="entry name" value="Chordopox_A30L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0597">Phosphoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099308" description="Protein A30 homolog">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="74" mass="8580" checksum="E41581447F94752C" modified="2000-10-01" version="1">MDDIDYIDDINEDSINHMLSTLANVRDPEFSATISLMQEVLKIINSRIIEIDKKYKKNNRNINSMNNASSRVSY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J540</accession>
    <name>RP35_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>DNA-directed RNA polymerase 35 kDa subunit</fullName>
            <ecNumber>2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">RPO35</name>
        <name type="ordered locus">FPV193</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. DNA-dependent RNA polymerase associates with the early transcription factor (ETF) thereby allowing the early genes transcription. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The DNA-dependent RNA polymerase used for intermediate and late genes expression consists of eight subunits 147 kDa, 133 kDa, 35 kDa, 30 kDa, 22 kDa, 19 kDa, 18 kDa and 7 kDa totalling more than 500 kDa in mass. The same holoenzyme, with the addition of the transcription-specificity factor RAP94, is used for early gene expression.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Virion</location>
        </subcellularLocation>
        <text evidence="1">All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviridae DNA-directed RNA polymerase 35 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039156.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J540"/>
    <dbReference type="GeneID" id="1486765"/>
    <dbReference type="KEGG" id="vg:1486765"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019083">
        <property type="term" value="P:viral transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005059">
        <property type="entry name" value="DNA-dir_RNA_pol_35kDa_poxviral"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03396">
        <property type="entry name" value="Pox_RNA_pol_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000746">
        <property type="entry name" value="Rpo35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099137" description="DNA-directed RNA polymerase 35 kDa subunit">
        <location>
            <begin position="1"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="302" mass="35128" checksum="8E2A46918FE29F6C" modified="2000-10-01" version="1">MHRQEYRIDVSANPSIATFIKHMCKKHLVIPRLNVGVVMINTTTAINEEWLTSIESLPTHKIFYDYVYDIIAMQCNFCIHLKKTQKENDSYISLADIDYYIIKPEEVIKLDPIKELKETLLHSFSEYRATNTKTIELAAFSSGTKINDELVNRLSFLDTELFNREYKNVKIIHSQNYETYFPFSIIAPEGNISIFMEKYTWFNSSVYFKSMLSYLKEVISDQIAEFNITKLDMEKDTPTSSAYDPKSNIVFVNDITTMCIINFFGCECQLGTYHKFNISSINTKTFHKAVNKTISEIYKAIN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J544</accession>
    <name>RP132_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>DNA-directed RNA polymerase 132 kDa polypeptide</fullName>
            <ecNumber>2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">RPO132</name>
        <name type="ordered locus">FPV189</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. DNA-dependent RNA polymerase associates with the early transcription factor (ETF), itself composed of D6 and A7, thereby allowing the early genes transcription. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The DNA-dependent RNA polymerase used for intermediate and late genes expression consists of eight subunits (147) kDa, (133) kDa, (35) kDa, (30) kDa, (22) kDa, (19) kDa, (18) kDa and (7) kDa totalling more than 500 kDa in mass. The same holoenzyme, with the addition of the transcription-specificity factor RAP94, is used for early gene expression.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039152.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J544"/>
    <dbReference type="GeneID" id="1486761"/>
    <dbReference type="KEGG" id="vg:1486761"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024390">
        <property type="entry name" value="RNA_pol_132_poxvirus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12415">
        <property type="entry name" value="rpo132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000048067" description="DNA-directed RNA polymerase 132 kDa polypeptide">
        <location>
            <begin position="1"/>
            <end position="1161"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="1161" mass="133469" checksum="334C2FC5DD63584F" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J547</accession>
    <name>Q9J547_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA polymerase processivity factor component A20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">FPV185</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">NVSL</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays an essential role in viral DNA replication by acting as the polymerase processivity factor together with protein D4. May serve as a bridge which links the DNA polymerase E9 and the uracil DNA glycosylase.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with the DNA polymerase catalytic subunit E9. Interacts with UDG. Component of the Uracil-DNA glycosylase(UDG)-A20-polymerase complex; A20 and UDG form a heterodimeric processivity factor that associates with E9 to form the processive polymerase holoenzyme. Interacts with D5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the poxviruses A20 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039149.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486757"/>
    <dbReference type="KEGG" id="vg:1486757"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010267">
        <property type="entry name" value="Chordopox_A20R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05941">
        <property type="entry name" value="Chordopox_A20R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AAF44529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="433" mass="50809" checksum="2CED19D8A0C33758" modified="2000-10-01" version="1">MSKSKDLDKLRELLKLKKNIHLLGKNNTVRYNELLDWTTKSYWSVGSIHIEEHVCVDEYYQSIKNNSYLLQGRYYFLHKYFGTKYVYLHESFYELSGGTTEATIEKSLKDKIKLVTNKYPDIRFILFVEYKNTFAIEDIVSKDNYKLYDILKFSKSVGLKVNGCLSLQIDKKTQFTKEYYELIHTNIEKIKGFYINGLICIREDTLVREVSDAKSNEFCCVQSIKLEKIDDNLWLPYAITFNNQVLKISGFKSLVRARLYVGSFVSVIKYRNILLLPDSTVPDKQIPKNEYIRKILEYFNNEYFSIGNYMVKTGTIEINKIGNSVTGILLPFSNSEELKQKLEDVEFVNKLKSRSLFDLSCDYFLQDREKVIKLINEMDFKLDDNNKIVEFDLNSESVIKGDRILEDIYMKFHQFVIVFNSLSTAKSMLPDNQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J548</accession>
    <name>A21_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Virion membrane protein A21 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV186</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Envelope protein part of a stable entry-fusion complex (EFC) which is at least composed of proteins A16, A21, A28, G3, G9, H2, J5, and L5. Formation of the viral membrane is necessary for the assembly of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Virion membrane</location>
            <topology evidence="3">Single-pass type III membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">Component of the mature virion (MV) membrane. The mature virion is located in the cytoplasm of infected cells and is probably released by cell lysis (By similarity).</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Contains two intramolecular disulfide bonds. They are created by the viral disulfide bond formation pathway, a poxvirus-specific pathway that operates on the cytoplasmic side of the MV membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the chordopoxvirinae A21 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039148.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486758"/>
    <dbReference type="KEGG" id="vg:1486758"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019031">
        <property type="term" value="C:viral envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055036">
        <property type="term" value="C:virion membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039663">
        <property type="term" value="P:membrane fusion involved in viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046718">
        <property type="term" value="P:viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007987">
        <property type="entry name" value="Poxvirus_A21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05323">
        <property type="entry name" value="Pox_A21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-1168">Fusion of virus membrane with host membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0735">Signal-anchor</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0261">Viral envelope protein</keyword>
    <keyword id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <keyword id="KW-1160">Virus entry into host cell</keyword>
    <feature type="chain" id="PRO_0000099274" description="Virion membrane protein A21 homolog">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Signal-anchor for type III membrane protein" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="topological domain" description="Virion surface" evidence="2">
        <location>
            <begin position="24"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="113" mass="13210" checksum="64424E058B2D4880" modified="2000-10-01" version="1">MFVLFLIVCYFILIFNIIVPKIADKLRLEHEAFTKYRQIYGNKFRCIGDNLINYSFTPFGVKANYLVNKNTKMPAICNDIKNINSLIAVTCDDASKFIKHRNICERAYTELFL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J550</accession>
    <name>A18_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Transcript termination protein A18</fullName>
            <ecNumber>3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV183</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">DNA helicase which seems to act as a postreplicative transcription termination factor. Involved in ATP-dependent release of nascent RNA. Forms a stable complex with single-stranded DNA, and to a lesser extent RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with G2. Might be part of a transcription complex composed at least of G2, A18, and H5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Localizes to the virion core.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the helicase family. Poxviruses subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039146.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486755"/>
    <dbReference type="KEGG" id="vg:1486755"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0347">Helicase</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000102180" description="Transcript termination protein A18">
        <location>
            <begin position="1"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="99"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="308"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DEAH box">
        <location>
            <begin position="205"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="112"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="462" mass="53501" checksum="2A7786A6B27E4A93" modified="2000-10-01" version="1">MSYITVIDDKLYSSLRKLVGYSPLYLFNDKGDFVEVMKNSEFRFLIPSGYFSNSNVPLYGLTFSYGRNWMKDRQKIILPELYPIQRRVIEEIILQFSRKCKEKRPLYTTLHLACGFGKTVTASYLIGTHKKNAVVSVPNKLILKQWENSISSLKVSYYVSYEGVSKLLKVLTSKSFSILVVVDKHFSNKEFCELVYENYDVFILDEAHIYNLMNESIMTSFLCYYPPRICYFLTATPRQQNAVYCNSIINFIKFSPLQKILYVIRELYNEYTNPSIRAHVSQLQTTANKYHLYTEKALAEDIHRNKTIVDKIIETFKTNQGNRILVITKLRNHMIIIYNDLRKVLSDKVYLGDAQKKSTTDMIKELRTIDNFILVSTLHYAGTGLDIPNLDSLFICNTVMNSMQSEQVMGRICRDTGSSPTRSIYLFINTSIKEIKSLVGVFTQRFAQQATKLGFREVSQMA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J554</accession>
    <name>A14_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Virion membrane protein A14 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV179</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Envelope protein which is a major component of the mature virion (MV) membrane. Essential for membrane biogenesis. Is required, together with A17, to form bona fide crescents, which can progress to form the immature virion (IV) membrane. A14 and A17 form a lattice that is stabilized by disulfide bonds and serves as an anchor within the viral membrane to which several other proteins important in virion structure and morphogenesis attach.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer; disulfide-linked. Interacts with A17.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Virion membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">Component of the mature virion (MV) membrane.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Phosphorylated by viral F10 kinase, phosphorylation state is regulated by H1 phosphatase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the chordopoxvirinae A14 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039142.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J554"/>
    <dbReference type="GeneID" id="1486727"/>
    <dbReference type="KEGG" id="vg:1486727"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008785">
        <property type="entry name" value="Poxvirus_A14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05767">
        <property type="entry name" value="Pox_A14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0597">Phosphoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0261">Viral envelope protein</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099244" description="Virion membrane protein A14 homolog">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="topological domain" description="Intravirion" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="topological domain" description="Virion surface" evidence="2">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="topological domain" description="Intravirion" evidence="2">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Interchain" evidence="1">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="91" mass="9950" checksum="64FE7AEECFD3849D" modified="2000-10-01" version="1">MDPLGFFRNRPSYVVVFGIILLIVACICAYIELSKSGKPADSALRSISIISFILAILLLLGIILFSGYNRYCTGNVVDESRYATSPGTEIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J556</accession>
    <name>Q9J556_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein FPV177</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV177</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039140.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486725"/>
    <dbReference type="KEGG" id="vg:1486725"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="68" mass="8014" checksum="1D5E4A281543C9F1" modified="2000-10-01" version="1">MSIIIIIFFVLICYFALFFYTSSGVIFGPDYKRYKDGDIIADRINEEKVKIKKIAKNIDVVNRELLKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J557</accession>
    <name>Q9J557_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">25 kDa core protein A12L</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FPV176</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">NVSL</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the virion core that undergoes proteolytic processing during the immature virion (IV) to mature virion (MV) transition. Essential for the formation of a structurally normal core.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the chordopoxvirinae A12 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039139.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486724"/>
    <dbReference type="KEGG" id="vg:1486724"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006744">
        <property type="entry name" value="Poxvirus_A12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04651">
        <property type="entry name" value="Pox_A12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0426">Late protein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0946">Virion</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="42"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AAF44520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="171" mass="18261" checksum="6DF52AA28303FF83" modified="2000-10-01" version="1">MTGKRGSQQHSSFNEYVEAMHKLNPQLKSLLNHINAITANTPPNFSEGSLPSTPPASNNSPTPKDVTAGAPRKSSRCTGTTSTRKPCSRRRGGAMASNEQEVQAVTNSGKIVYGVITGDGQLEVKGHVGEVNEDLLGIDLDIVNGGRKTRTKRTSRKKRMSNDNSIDGGMA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J558</accession>
    <name>A11_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein A11 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV175</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Required for viral crescent formation early during virus morphogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homomultimer. Interacts with A32.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">Localizes to the cytoplasmic viral factory. Not incorporated into virus particles. Does not seem to be a transmembrane protein (By similarity).</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Phosphorylated by a F10-independent mechanism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the poxviridae A11 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039138.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486723"/>
    <dbReference type="KEGG" id="vg:1486723"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007755">
        <property type="entry name" value="Poxvirus_A11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05061">
        <property type="entry name" value="Pox_A11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0175">Coiled coil</keyword>
    <keyword id="KW-1035">Host cytoplasm</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0597">Phosphoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099234" description="Protein A11 homolog">
        <location>
            <begin position="1"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="106"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="274" mass="31347" checksum="D4ACBC82F8135711" modified="2000-10-01" version="1">MTGLMVTDITNIAKEYNLTAFSEDVYPCNKNYELTNGQLSALKTINVVLTTRSDNYEKDVTYNDDDDHDRCIVSEIGSHHSFNDEKDNYIQSNNIQQTPSLSAVFDDNKRVHLLEQEIAELRKKKTKSKNLLDFTNTLFNKNPLRIGILNKRAIILNYASMNNSPLTMEDLEACEDEEIENMYISIKQYHEVHKKKLIVTNIISILISVIEQLLVRIGFDEIKGLSKEVTSTIIDLEIGEDCEQLATKMGVANNPVINISLFILKIFIRRINIL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J559</accession>
    <name>P4A_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Major core protein 4a precursor</fullName>
            <shortName>p4a</shortName>
        </recommendedName>
        <alternativeName>
            <fullName>Virion core protein 4a precursor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV174</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Core protein 4a is the most abundant virion protein. Major component of the virion core that undergoes proteolytic processing during the immature virion (IV) to mature virion (MV) transition.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with P39/A4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Probably localizes to the virion core wall.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviridae protein P4a family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039137.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="PRIDE" id="Q9J559"/>
    <dbReference type="GeneID" id="1486722"/>
    <dbReference type="KEGG" id="vg:1486722"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044423">
        <property type="term" value="C:virion component"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005058">
        <property type="entry name" value="Poxvirus_P4A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03395">
        <property type="entry name" value="Pox_P4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099217" description="Major core protein 4a precursor">
        <location>
            <begin position="1"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="891" mass="102269" checksum="21D64EE473D74B72" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-04-27" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J562</accession>
    <name>ETF2_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Early transcription factor 82 kDa subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>ETF large subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">VETFL</name>
        <name type="ordered locus">FPV171</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Acts with RNA polymerase to initiate transcription from early gene promoters. Is recruited by the RPO-associated protein of 94 kDa (RAP94) to form the early transcription complex, which also contains the core RNA polymerase. ETF heterodimer binds to early gene promoters.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of a 70 kDa and a 82 kDa subunit. Part of the early transcription complex composed of ETF, RAP94, and the DNA-directed RNA polymerase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviridae VETF large subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039134.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J562"/>
    <dbReference type="PRIDE" id="Q9J562"/>
    <dbReference type="GeneID" id="1486719"/>
    <dbReference type="KEGG" id="vg:1486719"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007532">
        <property type="entry name" value="Poxvirus_early-TF_lsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04441">
        <property type="entry name" value="Pox_VERT_large"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0010">Activator</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099084" description="Early transcription factor 82 kDa subunit">
        <location>
            <begin position="1"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="709" mass="82730" checksum="79C39E93A84E051C" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J563</accession>
    <name>A6_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein A6 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV170</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an essential role in immature virion (IV) to mature virion (MV) transition.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Localizes to the virion core.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae A6 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
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        <property type="chains" value="A/B=124-374"/>
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        <property type="chains" value="A=119-374"/>
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    <keyword id="KW-0002">3D-structure</keyword>
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            <begin position="1"/>
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        </location>
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        </location>
    </feature>
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            <end position="162"/>
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    </feature>
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            <end position="176"/>
        </location>
    </feature>
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            <end position="188"/>
        </location>
    </feature>
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            <end position="194"/>
        </location>
    </feature>
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            <end position="206"/>
        </location>
    </feature>
    <feature type="helix" evidence="3">
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            <end position="220"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="helix" evidence="3">
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            <end position="242"/>
        </location>
    </feature>
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            <end position="252"/>
        </location>
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        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
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        <location>
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            <end position="294"/>
        </location>
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            <end position="373"/>
        </location>
    </feature>
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    <evidence type="ECO:0007829" key="3">
        <source>
            <dbReference type="PDB" id="6BR9"/>
        </source>
    </evidence>
    <sequence length="374" mass="43748" checksum="E460DBA5B0B31CDC" modified="2000-10-01" version="1">MEKFRNAFIEFYELSKKYLENSTGQKVYEVNYDNDIDSFLTVFPILESKIGGDINCAMSDETVILAMQQVEFKMFTFWYMRSAANVKSMLNKITDKETKEQFIRIFKDMLVYAKVITSINNMYSNMKKDTNEIVQDLKKILGIVSLIKSANNEHQAYKILMENNSFIIRTINKVLADSNYIIKIIALFNTDVVSDKIKLEEYKDVFSFSKENVIFGIKCFCDITIDGIDQINNKYVSFFKKVLPNIILFQTSCVKTTQFVNIFSKLSSIVYSEILTNERLHVLFSEIMASFKTKVSVEDLKKRKVNNIQGLISEISNNREMYKNIFVEEYEKHKTTLISIVQCITDNYNINYKENAVDIEFIFDFIQEHYISKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J564</accession>
    <name>Q9J564_FOWPN</name>
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        </submittedName>
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        <name evidence="2" type="primary">FPV168</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
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        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
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            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
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        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
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        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
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    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="83"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="288" mass="30875" checksum="592894F9883B179E" modified="2000-10-01" version="1">MAENFHKDFISRIKRNVSNNPEIFSEKLDEDDSRNEKESIVDEYNTDDSRSIQDRMISILRSNDTAGIFTSFLNRFNNQQSSNLPYPQNLGPPSYNSSTTLPSTSGNQGTSSSVSGLAPQGTSSSVSGLAPQGTSSSVSGLAPQGTSSSVSGLAPQGLSSLSSNIGLQGPSSLSSNSSFGPQTTSSSGSSFGPQTPSSSSSSSTLVPSSNIQQSQVLTLPSSTPLWIRNLHDKYIDILPPIKVPLSNSNKIDKQMFFDEVITWINIYLQEKGIMLPDDIRELRDAIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J571</accession>
    <name>Q9J571_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV160</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV160</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
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        <lineage>
            <taxon>Viruses</taxon>
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            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
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            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
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    </organism>
    <organismHost>
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        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
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    <dbReference type="Proteomes" id="UP000008597">
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="156" mass="18477" checksum="03F18B0D305803AE" modified="2000-10-01" version="1">MSLSDKDTKTHGDYQPSNEQILQKIRRTMENEADSLNRRSIKEIVVDVMKNWDHPLNEEIDKVLNWKNDTLNDLDHLNTDDNIKEIIQCLIREFAFKKINSIMYSYAMVKLNSDNETLKDKIKDYFIETILKDKRGYKQKPLPGLETKILDSIIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J573</accession>
    <name>Q9J573_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">E3 ubiquitin-protein ligase makorin-2</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">RING-type E3 ubiquitin transferase makorin-2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">FPV157</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">NVSL</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039120.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486705"/>
    <dbReference type="KEGG" id="vg:1486705"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039648">
        <property type="term" value="P:modulation by virus of host protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017880">
        <property type="entry name" value="KilA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA_N/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026293">
        <property type="entry name" value="Makorin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045072">
        <property type="entry name" value="MKRN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224">
        <property type="entry name" value="PTHR11224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224:SF17">
        <property type="entry name" value="PTHR11224:SF17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51301">
        <property type="entry name" value="KILA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0221">Differentiation</keyword>
    <keyword evidence="7" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1128">Modulation of host ubiquitin pathway by viral E3 ligase</keyword>
    <keyword evidence="5" id="KW-1130">Modulation of host ubiquitin pathway by virus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="KilA-N" evidence="18">
        <location>
            <begin position="34"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="17">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="16">
        <location>
            <begin position="218"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="15">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="AAF44501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="311" mass="36592" checksum="5DB2C18B8CA2D9B4" modified="2000-10-01" version="1">MKEDDSSNINNIHGKYSVSDLSQDDYVIECIDGSFDSIKYRDIKVIIMKNNGYVNCSKLCKMRNKYFSRWLRLSTSKALLDIYNNKSVDNAIVKVYGKGKKLIITGFYLKQNMIRYVIEWIGDDFTNDIYKMINFYNALFGNDELKIVSCENTLCPFIELGRCYYGKKCKYIHGDQCDICGLYILHPTDINQRVSHKKTCLVDRDSLIVFKRSTSKKCGICIEEINKKHISEQYFGILPSCKHIFCLSCIRRWADTTRNTDTENTCPECRIVFPFIIPSRYWIDNKYDKKILYNRYKKMIFTKIPIRTIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J580</accession>
    <name>Q9J580_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ORF FPV150 N1R/p28 gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FPV150</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039113.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486698"/>
    <dbReference type="KEGG" id="vg:1486698"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039648">
        <property type="term" value="P:modulation by virus of host protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017880">
        <property type="entry name" value="KilA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA_N/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026294">
        <property type="entry name" value="Makorin_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045072">
        <property type="entry name" value="MKRN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224">
        <property type="entry name" value="PTHR11224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11224:SF38">
        <property type="entry name" value="PTHR11224:SF38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51301">
        <property type="entry name" value="KILA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1128">Modulation of host ubiquitin pathway by viral E3 ligase</keyword>
    <keyword evidence="1" id="KW-1130">Modulation of host ubiquitin pathway by virus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="KilA-N" evidence="9">
        <location>
            <begin position="12"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="196"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AAF44494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="276" mass="31917" checksum="B704DD9013F6E92B" modified="2000-10-01" version="1">MSHLHLNNGDTEYRVIEDNGFSIILLKHTEYINVTKLCKIHNKEFYRWKRLISAGRIIETVSRDISNQGFESPLVYVNRKGNKEFYGFYAHPQLALYIAKWISEDIFNKIKHLINSYTISDKTVVIKDFSYCDELCPDAIIGKCCKTKSSCEYVHGDICDICGFEALHPTDIDKRLTHEKVCMQLLCKEDIKYDKCGICLDAIKGNKKPYGILSDCNHMFCINCIKTWMTTINSKKQCPECRVPSKYIIQSPIWTVDKVSKNQLSVSYKTVYIKSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J582</accession>
    <name>Q9J582_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ORF FPV148 Virion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">FPV148</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">NVSL</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Late protein which is part of a large complex required for early virion morphogenesis. This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae D2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039111.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486696"/>
    <dbReference type="KEGG" id="vg:1486696"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006791">
        <property type="entry name" value="Pox_D2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04701">
        <property type="entry name" value="Pox_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0426">Late protein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0946">Virion</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AAF44492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="139" mass="16494" checksum="CEB786ED87665F05" modified="2000-10-01" version="1">MELELKSIGLINIHTLFNKVIRFQQDINNILKSDYIIVSFCDNGKLFEIYNFDKVARFDNGIIYQQIKNVYKDRHDYLPVIFPSQNILESFNEEFPIRKESSTLRIPSANKHPKMILLELFNSFKTNKVLGCCYYYTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J583</accession>
    <name>Q9J583_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV147 HT motif gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV147</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039110.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486695"/>
    <dbReference type="KEGG" id="vg:1486695"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="104" mass="12685" checksum="AB7468F313419D94" modified="2000-10-01" version="1">MGPELYHTDAMTFSLSDKYDIYGIFRTFHINTDGKYSKPGSLYDYYITYNTDGVESYFLFERATEEQLYKILKSYNYLLITKVTVYPNDNSYDRRYKHRRDRRY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J584</accession>
    <name>MCEL_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>mRNA-capping enzyme catalytic subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Virus termination factor large subunit</fullName>
            <shortName>VTF large subunit</shortName>
        </alternativeName>
        <alternativeName>
            <fullName>mRNA-capping enzyme 97 kDa subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>mRNA-capping enzyme large subunit</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName>Polynucleotide 5'-triphosphatase</fullName>
                <ecNumber>3.1.3.33</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName>mRNA 5'-triphosphatase</fullName>
                <shortName>TPase</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName>mRNA guanylyltransferase</fullName>
                <ecNumber>2.7.7.50</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName>GTP--RNA guanylyltransferase</fullName>
                <shortName>GTase</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName>mRNA (guanine-N(7))-methyltransferase</fullName>
                <ecNumber>2.1.1.56</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName>mRNA cap methyltransferase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name type="ordered locus">FPV146</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalytic subunit of the mRNA capping enzyme which catalyzes three enzymatic reactions: the 5' triphosphate end of the pre-mRNA is hydrolyzed to a diphosphate by RNA 5' triphosphatase; the diphosphate RNA end is capped with GMP by RNA guanylyltransferase and the GpppN cap is methylated by RNA (guanine-N7) methyltransferase. Heterodimeric mRNA capping enzyme catalyzes the linkage of a N7-methyl-guanosine moiety to the first transcribed nucleotide (cap 0 structure), whereas the polymerase associated VP39 is responsible for a second methylation at the 2'-O position of the ribose (cap 1 structure).</text>
    </comment>
    <comment type="function">
        <text evidence="1">The heterodimeric enzyme is also involved in early viral gene transcription termination and intermediate viral gene transcription initiation. Early gene transcription termination requires the termination factor VTF, the DNA-dependent ATPase NPH-I and the Rap94 subunit of the viral RNA polymerase, as well as the presence of a specific termination motif. Binds, together with RAP94, to the termination motif 5'-UUUUUNU-3' in the nascent early mRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a 5'-end triphospho-(purine-ribonucleoside) in mRNA + H2O = a 5'-end diphospho-(purine-ribonucleoside) in mRNA + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11008"/>
            <dbReference type="Rhea" id="RHEA-COMP:13929"/>
            <dbReference type="Rhea" id="RHEA-COMP:13942"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:138276"/>
            <dbReference type="ChEBI" id="CHEBI:138288"/>
            <dbReference type="EC" id="3.1.3.33"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a 5'-end diphospho-ribonucleoside in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-(ribonucleoside) in mRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:67012"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.7.7.50"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (5'-triphosphoguanosine)-(ribonucleoside) in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:67008"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.1.1.56"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of a catalytic and a regulatory subunit. Intrinsic methyltransferase activity of the catalytic subunit is weak and needs to be stimulated 30- to 50-fold by the regulatory subunit, which is itself catalytically inert.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Virion</location>
        </subcellularLocation>
        <text>All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The N-terminus contains the triphosphatase and guanylyltransferase domains, whereas the C-terminus contains the methyltransferase domain. The N-terminus is involved in binding to the termination motif 5'-UUUUUNU-3' in the nascent mRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.33"/>
    <dbReference type="EC" id="2.7.7.50"/>
    <dbReference type="EC" id="2.1.1.56"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039109.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J584"/>
    <dbReference type="GeneID" id="1486694"/>
    <dbReference type="KEGG" id="vg:1486694"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004482">
        <property type="term" value="F:mRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004651">
        <property type="term" value="F:polynucleotide 5'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019602">
        <property type="entry name" value="mRNA_cap_ATPase/GuylTrfase_vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004971">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039753">
        <property type="entry name" value="RG7MT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189">
        <property type="entry name" value="PTHR12189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10640">
        <property type="entry name" value="Pox_ATPase-GT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03291">
        <property type="entry name" value="Pox_MCEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51562">
        <property type="entry name" value="RNA_CAP0_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-0506">mRNA capping</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000210130" description="mRNA-capping enzyme catalytic subunit">
        <location>
            <begin position="1"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="domain" description="mRNA cap 0 methyltransferase" evidence="3">
        <location>
            <begin position="521"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Triphosphatase-guanylyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="active site" description="N6-GMP-lysine intermediate" evidence="1">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic; for RNA triphosphatase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic; for RNA triphosphatase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic; for RNA triphosphatase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic; for RNA triphosphatase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="554"/>
            <end position="555"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="574"/>
            <end position="575"/>
        </location>
        <ligand>
            <name>mRNA</name>
            <dbReference type="ChEBI" id="CHEBI:33699"/>
        </ligand>
        <ligandPart>
            <name>mRNA cap</name>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="578"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="603"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="625"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="683"/>
            <end position="685"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="site" description="Essential for RNA triphosphatase activity" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="site" description="Essential for RNA triphosphatase activity" evidence="1">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="site" description="Essential for RNA triphosphatase activity" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="site" description="Essential for RNA triphosphatase activity" evidence="1">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="site" description="Essential for RNA triphosphatase activity" evidence="1">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="3">
        <location>
            <position position="612"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="3">
        <location>
            <position position="637"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="3">
        <location>
            <position position="687"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="3">
        <location>
            <position position="768"/>
        </location>
    </feature>
    <feature type="site" description="mRNA cap binding" evidence="3">
        <location>
            <position position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000250" key="2">
        <source>
            <dbReference type="UniProtKB" id="P04298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="851" mass="98888" checksum="DC3607ADD634BA7A" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J585</accession>
    <name>Q9J585_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV145 Molluscum contagiosum virus MC089L homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV145</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039108.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486693"/>
    <dbReference type="KEGG" id="vg:1486693"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="103" mass="12259" checksum="135A0206E0C6E08E" modified="2000-10-01" version="1">MIVILVIYIIVIVFFLFMLTKKATSVRLDKDNMILSGLYKDKITAQNTLVKLQEELSEKKTNYSAWYDLTSSNELNKHKDIKRMDPYTAMKFTYDLLDRWRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J587</accession>
    <name>Q9J587_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA topoisomerase I</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FPV143</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">NVSL</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type IB topoisomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039106.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486691"/>
    <dbReference type="KEGG" id="vg:1486691"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.66.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035447">
        <property type="entry name" value="DNA_topo_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001631">
        <property type="entry name" value="TopoI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027362">
        <property type="entry name" value="TopoI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014711">
        <property type="entry name" value="TopoI_cat_a-hlx-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013500">
        <property type="entry name" value="TopoI_cat_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015346">
        <property type="entry name" value="TopoI_N_vir"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01028">
        <property type="entry name" value="Topoisom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09266">
        <property type="entry name" value="VirDNA-topo-I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00416">
        <property type="entry name" value="EUTPISMRASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55869">
        <property type="entry name" value="SSF55869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0426">Late protein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="VirDNA-topo-I_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Topoisom_I" evidence="7">
        <location>
            <begin position="93"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AAF44487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="316" mass="37174" checksum="6905BB781A6A1292" modified="2000-10-01" version="1">MVKKVFFHYKDDKLYYDAAYKNLVPASNKTYEIIKAYRVPPHLKEVIVYEQSLEEASNSLIFIGVDSKGRKQYFYGKNHVILRNKNRDKVFIKVHKIIKKINNYIDKNICSESNTLEFQLAVFMLMETSFYIRIGKVKYYKQNDTVGLLTLQNKHLTVTDENITIKFTGKDKVVHAFNVKKENRLYEPLLRIHDFSKPDSVLFSLLSEKKVYSFIKQYSIKIKDLRTYGVNITFLYNIWNNVISMLKLPSIKKLIVLSIKQTADTIGHTPNISKQAYMAITILELMKEENITETIKQKTFDEFLNFVINYVNKKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2021-06-02" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J588</accession>
    <name>Q9J588_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV142 Late transcription factor VLTF-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV142</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039105.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486690"/>
    <dbReference type="KEGG" id="vg:1486690"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="174" mass="19250" checksum="84F1DDE996282680" modified="2000-10-01" version="1">MSWTNSEDKSFKTIDELKAKVKADSSHHVSNSASDTEPEMIPEVVKKPTKKTAKKTKKQELASCNSSNPNTDPFTKDLDLYDLDVLSDGKCAEENKPSSIDLVETRLVIKTISKSIKDIAHRIAALRSVIHDLDLTDIPKNTGQAIKEVDKLKEALCNLGVSVPPPKQQRKKAK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J590</accession>
    <name>VP35_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Immunodominant envelope protein p35</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Ag35</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>Virion envelope protein p35</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV140</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Envelope protein that binds to the cell surface to provide virion attachment to target cell.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Virion membrane</location>
            <topology evidence="4">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the poxviruses protein p35 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039103.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J590"/>
    <dbReference type="GeneID" id="1486688"/>
    <dbReference type="KEGG" id="vg:1486688"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004900">
        <property type="entry name" value="Poxvirus_P35"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03213">
        <property type="entry name" value="Pox_P35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0945">Host-virus interaction</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-1161">Viral attachment to host cell</keyword>
    <keyword id="KW-0261">Viral envelope protein</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <keyword id="KW-1160">Virus entry into host cell</keyword>
    <feature type="chain" id="PRO_0000099210" description="Immunodominant envelope protein p35">
        <location>
            <begin position="1"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="327" mass="38014" checksum="C1F374A84E8EDA02" modified="2000-10-01" version="1">MAPGDKKQIIFVITTIGRPSSTVVPFKNLEVSEWSYKKGIKNGYDDYRDPPSPKPLPKSKQEPNADDKVGDIEYDEMVSVRDGYYSDVCRLTCTEDTKIFIADHISLWRYIMDNAEKLPNYVVIMEDDNTITGEGFITNLDNITKVLNDNNVDILQLVTHTKLLKDRNSQHLMLLPDLEAFKGSFDVSLSAYIIRQEAVRKLYSYFTNNKPSFDISLEILRIENTLGITRYVVDNDRYVYHDYKLANEFMKNKKNRLSIKSRIDGWIMDNWPSFYHRMYYPLFSVFGKYDITMMFLIAIVIIIGLAIFDINNKLLWLLSGVFLAYSM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J592</accession>
    <name>DUSP_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Probable dual specificity protein phosphatase H1 homolog</fullName>
            <ecNumber>3.1.3.-</ecNumber>
            <ecNumber>3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV138</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Serine/Tyrosine phosphatase which down-regulates cellular antiviral response by dephosphorylating activated STAT1 and blocking interferon (IFN)-stimulated innate immune responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:10137"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:82620"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Host cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">Approximately 200 molecules of H1 are packaged within the virion and are essential for the viability of the virus.</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-"/>
    <dbReference type="EC" id="3.1.3.48"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039101.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J592"/>
    <dbReference type="GeneID" id="1486686"/>
    <dbReference type="KEGG" id="vg:1486686"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030430">
        <property type="term" value="C:host cell cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039563">
        <property type="term" value="P:suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039502">
        <property type="term" value="P:suppression by virus of host type I interferon-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-1035">Host cytoplasm</keyword>
    <keyword id="KW-0945">Host-virus interaction</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1090">Inhibition of host innate immune response by virus</keyword>
    <keyword id="KW-1114">Inhibition of host interferon signaling pathway by virus</keyword>
    <keyword id="KW-1105">Inhibition of host STAT1 by virus</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0904">Protein phosphatase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0899">Viral immunoevasion</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000094870" description="Probable dual specificity protein phosphatase H1 homolog">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="2">
        <location>
            <begin position="25"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate" evidence="2">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="166" mass="19637" checksum="D98A7C95DAB29BD6" modified="2000-10-01" version="1">MDEKQLYKHIITKSTNTCVKFTPRDITKITDYVYLGNYRNVIELPNKTFFKYIVNVSMLKYKLKRTDITVLHFPLEDNDTVSISKHIDAVTYVLKKCESLKIPVLVHCMAGINRSSAMIMGYLMEIRDKNIPFVIYFLYIYHELKYIRGAFIENKSFLNQIIDKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J599</accession>
    <name>Q9J599_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ORF FPV123 variola B22R gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FPV123</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039086.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486671"/>
    <dbReference type="KEGG" id="vg:1486671"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007490">
        <property type="entry name" value="Poxvirus_B22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025128">
        <property type="entry name" value="Poxvirus_B22R_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025133">
        <property type="entry name" value="Poxvirus_B22R_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04395">
        <property type="entry name" value="Poxvirus_B22R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13168">
        <property type="entry name" value="Poxvirus_B22R_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13169">
        <property type="entry name" value="Poxvirus_B22R_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poxvirus_B22R_N" evidence="3">
        <location>
            <begin position="35"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Poxvirus_B22R_C" evidence="2">
        <location>
            <begin position="805"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="541"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AAF44467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="1766" mass="201147" checksum="B3D87FF4A52679D9" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-10-07" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5A6</accession>
    <name>Q9J5A6_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV116 CC chemokine gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV116</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039079.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486664"/>
    <dbReference type="KEGG" id="vg:1486664"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008009">
        <property type="term" value="F:chemokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006955">
        <property type="term" value="P:immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036048">
        <property type="entry name" value="Interleukin_8-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54117">
        <property type="entry name" value="SSF54117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="120" mass="13536" checksum="48EBDCE0906A9122" modified="2000-10-01" version="1">MEKLIIYSFILVVLNHVYGQYLYLGGLFSSPRKTIIMKLCCPSVDGDMLPADKIGSNIRATDCRCKSKPSIIVSTTKEEEKCFPPNTPWLEQAIKEKNLKIPKCVYYPNKIGAPKGFGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5B6</accession>
    <name>Q9J5B6_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV104</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV104</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039067.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486652"/>
    <dbReference type="KEGG" id="vg:1486652"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="210" mass="24690" checksum="1C8FC5203C0EC560" modified="2000-10-01" version="1">MFKNYKYTLLSEDTNNMKLLIPGLEDDMEAGTIENSGYRNISTKMFKDQVKDIVKKTYNQTYLQLLQLLERSNVDCNELELLYRIININPRICHRFYINRYDSIFGSFNKLHEFISNVMIKIFKIGNSIYITFISDNTSLEINVDNDTEGRLMNIDYTIKFGDVIILQLGRISIKFSGNFVIMKDILFLVTDSNKIVYNEDEFLLEIYNT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5C0</accession>
    <name>RPO5_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>DNA-directed RNA polymerase 30 kDa polypeptide</fullName>
            <ecNumber>2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">RPO30</name>
        <name type="ordered locus">FPV100</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Rpo30 may have a role in RNA chain elongation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text>This enzyme consists of at least eight subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the poxviridae DNA-directed RNA polymerase 30 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039063.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5C0"/>
    <dbReference type="GeneID" id="1486648"/>
    <dbReference type="KEGG" id="vg:1486648"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009162">
        <property type="entry name" value="RNA_pol_30_chordopoxvir-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024394">
        <property type="entry name" value="RNA_pol_30_chordopoxvir-type_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12410">
        <property type="entry name" value="rpo30_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="TFIIS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000745">
        <property type="entry name" value="VAC_RPO30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="chain" id="PRO_0000121459" description="DNA-directed RNA polymerase 30 kDa polypeptide">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="TFIIS-type" evidence="2">
        <location>
            <begin position="135"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="182" mass="21373" checksum="1D33E3B9D0DCCBEB" modified="2000-10-01" version="1">MDMMKIIKKYINSEEEAQKLLKWAIDNANIYYLRNIVNTKVNIEETKFKTVHNIGIEYSKDNKYKLSYRNKPSIATNEKYKELCNLIRSTNGIEKETLRYLLFGIKCVHAKVEYDIEKVPDYDYSNYFDVLKEKSTIRCVACKSNNTIPMILQTRSSDEEPTVRVVCKDCGKNFAPPRLKFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2021-06-02" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5C3</accession>
    <name>Q9J5C3_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ORF FPV097 variola B22R gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FPV097</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039060.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486645"/>
    <dbReference type="KEGG" id="vg:1486645"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007490">
        <property type="entry name" value="Poxvirus_B22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025128">
        <property type="entry name" value="Poxvirus_B22R_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025133">
        <property type="entry name" value="Poxvirus_B22R_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04395">
        <property type="entry name" value="Poxvirus_B22R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13168">
        <property type="entry name" value="Poxvirus_B22R_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13169">
        <property type="entry name" value="Poxvirus_B22R_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poxvirus_B22R_N" evidence="3">
        <location>
            <begin position="19"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Poxvirus_B22R_C" evidence="2">
        <location>
            <begin position="962"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="816"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="737"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="835"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="896"/>
            <end position="915"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AAF44441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="1912" mass="215981" checksum="9C4C709F671826FE" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5C5</accession>
    <name>Q9J5C5_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV095</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV095</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039058.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486643"/>
    <dbReference type="KEGG" id="vg:1486643"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005057">
        <property type="entry name" value="Poxvirus_E8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03394">
        <property type="entry name" value="Pox_E8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015690">
        <property type="entry name" value="VAC_E8R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="272" mass="31353" checksum="76150734B0D1EA9D" modified="2000-10-01" version="1">MTNANRGIRDIIGNAHERTDDQKTFNRMNLPPILNNTFLYHDYAYGWIPETALWNTQYEKLDIRSYYPITLGLLNKFEFMLGLHQGPPPQYTPKINIQYLNQISTVNLNDYFKKFSILPVDQLISFLLLTSIPIYNILFFFKNTTFNPRIHSLTGSFYIDDAKHIELAKYLIRGGDYKPIFGKLDRQGLYDGTLFPVNMATLQIPATSPNLYLLNIETLENLSVIISNTKQDPVLIFLIFYLPGLSVTTKITPAVEYLMNKLGLKKENVILV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5C8</accession>
    <accession>O72894</accession>
    <name>E11_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein E11 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV092</name>
        <name type="ORF">FPE11L</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1998" name="Virus Genes" volume="17" first="5" last="9">
            <title>Nucleotide sequence of the 4.3 kbp BamHI-N fragment of fowlpox virus FP9.</title>
            <authorList>
                <person name="Pollitt E."/>
                <person name="Skinner M.A."/>
                <person name="Heaphy S."/>
            </authorList>
            <dbReference type="PubMed" id="9778782"/>
            <dbReference type="DOI" id="10.1023/A:1008045914991"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Found in the core of mature virions (MV).</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae E11 family.</text>
    </comment>
    <dbReference type="EMBL" id="AJ223385">
        <property type="protein sequence ID" value="CAA11287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039055.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5C8"/>
    <dbReference type="GeneID" id="1486640"/>
    <dbReference type="KEGG" id="vg:1486640"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009201">
        <property type="entry name" value="Virion_core"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06138">
        <property type="entry name" value="Chordopox_E11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015797">
        <property type="entry name" value="Virion_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099471" description="Protein E11 homolog">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA11287." evidence="2" ref="1">
        <original>S</original>
        <variation>T</variation>
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="131" mass="15321" checksum="A946714AFE503D48" modified="2000-10-01" version="1">MELVNILLESESERVKLYYDIPPKKSLRTKCEVDRAVKYFISVIKKYIKLKESTFYVVVKDTTLFTYKYDKGELTPVDNTYYTFSKELASTDYSSSEITSICFTITDDMSISVKPKTGYIVKVRSDNSRYY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5C9</accession>
    <accession>O72898</accession>
    <name>I1_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Telomere-binding protein I1 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Protein FPV90</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV090</name>
        <name type="ORF">FPI1L</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1998" name="Virus Genes" volume="17" first="5" last="9">
            <title>Nucleotide sequence of the 4.3 kbp BamHI-N fragment of fowlpox virus FP9.</title>
            <authorList>
                <person name="Pollitt E."/>
                <person name="Skinner M.A."/>
                <person name="Heaphy S."/>
            </authorList>
            <dbReference type="PubMed" id="9778782"/>
            <dbReference type="DOI" id="10.1023/A:1008045914991"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Late DNA-binding protein which binds to the hairpin form of the viral telomeric sequence. Required for the production of mature virions (MV).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Present in the virus core.</text>
    </comment>
    <comment type="induction">
        <text>Expressed late in the viral replicative cycle.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">Each virion contains approximately 670 molecules of I1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae I1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AJ223385">
        <property type="protein sequence ID" value="CAA11291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039053.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486638"/>
    <dbReference type="KEGG" id="vg:1486638"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004969">
        <property type="entry name" value="Poxvirus_I1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03289">
        <property type="entry name" value="Pox_I1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015625">
        <property type="entry name" value="VAC_I1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099565" description="Telomere-binding protein I1 homolog">
        <location>
            <begin position="1"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA11291." evidence="2" ref="1">
        <original>YS</original>
        <variation>LC</variation>
        <location>
            <begin position="277"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="311" mass="35989" checksum="D3A5B19932983999" modified="2000-10-01" version="1">MEQFDQLVLNSISAKALKSYLTTKIAEAIDELAAKKNSPKKKAQTKKPENRIPLDLINKNFVSKFGLKGYKDGVLNSLICSLVENNYFENGKLKRGKHDELVLLDIEKEILARIDENSSLNIDVLDVKVLANRLRTNADRFEFKGHTYYLEQNKTEDIINQLIKNSAISMDMKNTIKDTFYMISDELLDVFKNRLFKCPQVKDNIISRARLYEYFIKATKPDDSKIYVILKDDNIAKILNIETIVIDHFIYTKHSLLVSSISNQIDKYSKKFNDQFYSSISEYIKDNEKINLSKVIEYLTISTVKIENTVE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5D0</accession>
    <accession>O72905</accession>
    <name>MP44_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Probable metalloendopeptidase G1-type</fullName>
            <ecNumber>3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV081</name>
        <name type="ORF">FPG1L</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="1998-01" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Pollitt E."/>
                <person name="Skinner M.A."/>
                <person name="Heaphy S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 286-626</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Seems to be involved in viral proteins maturation by cleavage at Ala-Gly-|-Xaa motifs.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M44 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AJ223385">
        <property type="protein sequence ID" value="CAA11300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="H48563">
        <property type="entry name" value="H48563"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039044.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5D0"/>
    <dbReference type="GeneID" id="1486629"/>
    <dbReference type="KEGG" id="vg:1486629"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019058">
        <property type="term" value="P:viral life cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005072">
        <property type="entry name" value="Peptidase_M44"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03410">
        <property type="entry name" value="Peptidase_M44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015679">
        <property type="entry name" value="Peptidase_M44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0482">Metalloprotease</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000218448" description="Probable metalloendopeptidase G1-type">
        <location>
            <begin position="1"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="626" mass="73949" checksum="98EA28BCF318B687" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2021-02-10" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5D1</accession>
    <name>Q9J5D1_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ORF FPV080 Transforming growth factor-beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FPV080</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039043.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486628"/>
    <dbReference type="KEGG" id="vg:1486628"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001839">
        <property type="entry name" value="TGF-b_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00019">
        <property type="entry name" value="TGF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00204">
        <property type="entry name" value="TGFB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="SSF57501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51362">
        <property type="entry name" value="TGF_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="TGF_BETA_2" evidence="2">
        <location>
            <begin position="249"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AAF44424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="363" mass="41947" checksum="C48D5E2BE4A7D1FF" modified="2000-10-01" version="1">MVCRNIIIFISSCLVYCVIGYGNLPSIKDLILSMIGENEENLQDEYYDTIVEVPENHKNKPSIDLHGMYGSGKYMNTAYFNTHDVYFVNRILNVSICIYLNTQHEEVVLKVICNCSINKICGTGDYHVLPADKWYCILLTENMAKQSIYNRHCNYTLLAPDGIINRTRHVFLEYYVNETEPKDDRYYTVSTNNRHRYISVEGLIKKLLSITDEEELYSDDHVDYSFDIRKRSIKSTDLPTESTNKMSVGSKKYVESDSGVDYSSPSDNCKVYRKYINFRSIGLKWILHPPGIDYGYCMGECQSFVYTDSFLYSLLAFHYIDGIELKQCCSIQSMDDLVVHYRLGRTPKTAILRKVSVKSCKCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5D4</accession>
    <name>Q9J5D4_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Glutaredoxin-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">FPV077</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">NVSL</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Glutaredoxin necessary for virion morphogenesis and virus replication.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Host cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glutaredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039040.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486625"/>
    <dbReference type="KEGG" id="vg:1486625"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030430">
        <property type="term" value="C:host cell cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008554">
        <property type="entry name" value="Glutaredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05768">
        <property type="entry name" value="Glrx-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="3 4" id="KW-1035">Host cytoplasm</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AAF44421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="125" mass="14387" checksum="460EDEDCB81C307C" modified="2000-10-01" version="1">MKGTIILFGKPNCPLCKFSNEILSNKKIASKYEIVRINIATFFDKSKVVEILGMDKSYDLLNSIGEKLGNEYVLVFRYDDTSKQMAYIPFKKYIVIGQISQDSIDFDKLLNELETTPYNILLKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5E0</accession>
    <name>Q9J5E0_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein FPV071</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV071</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039034.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486619"/>
    <dbReference type="KEGG" id="vg:1486619"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="SSF102645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DFP" evidence="1">
        <location>
            <begin position="133"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="289" mass="32995" checksum="56399B275B7A4A98" modified="2000-10-01" version="1">MDTTTNINNWVKLQKEKNRRVALVTSGGTRVSLEKKPVRFLENFSTGMRGAISVEKLIENGYSVCFLYREYSIFPWSRLLPSGNMLLSSLNVEGNTVYFNDALNTQLVSALKKYNEAIEQNKLLAISYTCIHQYLNFLEMISKSLSILGSHAVVYLAAAVSDFYIPEDEMYEHKIDSSTDITLELKTVPKMLFHLVDEWCPNAFVVSFKLETDKNMLVTKARQALYKYNHHVVIANSLDTRRTNVLLITNHSESNIVLSDKDSKEGIVIEDKIIKSIKEMHDEHIDKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5E5</accession>
    <name>Q9J5E5_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV066</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV066</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039029.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486614"/>
    <dbReference type="KEGG" id="vg:1486614"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="122" mass="14797" checksum="908629B0DB871662" modified="2000-10-01" version="1">MSIDEVNDILKHDGISPCYFGECREDILNLDVSEYNLYNIYEIKELYTRFLKDNYLDSIDTFKLDDNSLDHIMYHFTEYLSMLKNTVLSRKTICKRILNKDMYKKTKSRKLRNEFTYSNQKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5E6</accession>
    <name>Q9J5E6_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV065</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV065</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039028.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486613"/>
    <dbReference type="KEGG" id="vg:1486613"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="111" mass="13176" checksum="54C66C7C2C34E2B9" modified="2000-10-01" version="1">MVSNYCVVFMLNNYSSDDYKKIKSLDYHYLILDKHSDSSHKTISGYVELKDGISCSIIENINSRILYKKLQGNKDFLRINKKNIVDSFKSKGCYEEYRSRRLDLSIFDYYK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5F7</accession>
    <name>V045_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein FPV045</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV045</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039009.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5F7"/>
    <dbReference type="GeneID" id="1486593"/>
    <dbReference type="KEGG" id="vg:1486593"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099729" description="Uncharacterized protein FPV045">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <sequence length="73" mass="8658" checksum="BECBDE957AB6A036" modified="2000-10-01" version="1">MCLPKNPHPPVTTYTSVRILSINYIRPKLYFHFLLYYTIIKTNKYTNIIRNLEHVIKVLPFLLTACSCNCRLE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5G3</accession>
    <name>V040_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized serpin-like protein FPV040</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV040</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the serpin family. Poxviruses subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039003.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5G3"/>
    <dbReference type="MEROPS" id="I04.067"/>
    <dbReference type="GeneID" id="1486588"/>
    <dbReference type="KEGG" id="vg:1486588"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="PTHR11461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="SSF56574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0646">Protease inhibitor</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="chain" id="PRO_0000094155" description="Uncharacterized serpin-like protein FPV040">
        <location>
            <begin position="1"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="337" mass="38614" checksum="05B0AFCA802224DD" modified="2000-10-01" version="1">MDIIKIQLDVAIKIYNYIKSTGTENIIIAPCSIISSLCALSKLTDHSTADKIYDILNIECQNIDLYMKKINDNMNSSDIDYFCKLGLNNVCINQRTKNILYNCYKTCTVDETEGCSIKFKNVLEFEALWNRPFTAPTEEQIRKRHNSVEIVSILVDAKRRLHMLRRLDNIGCSVVRTSLASNRYILTTISPNEDKEEIFNLLENSINVDSLLDWIDNSKMKKAQHRLKIPKIKMSSSYDIVELLKSLGLNLMEIKFSNVFPETTLFVERIAQSSIMEIKAESISLNTDIELEFTNNEYPKINCSSCSETVVGKPFIFILQCRVTGNCIYFGVLRDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5G7</accession>
    <name>Q9J5G7_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV036</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV036</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038999.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486584"/>
    <dbReference type="KEGG" id="vg:1486584"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="153" mass="18105" checksum="D999FEEB3EE4E135" modified="2000-10-01" version="1">MKMKYNKYYTYIYSMNYHMISFIDDIDLYTECSRITDFYRLINNTKVINIFVSETLTNILSQYLLNNEYLAHVMLVMDINDYTLEVGNYSNFIILCIDSEDCGLLLHNDGKCIVLYPNNMVRFVSYPYNSIDIKNSIATDSKYNIIVFFISRT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5H4</accession>
    <name>V027_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>G-protein coupled receptor homolog FPV027</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV027</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Host cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038990.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5H4"/>
    <dbReference type="GeneID" id="1486746"/>
    <dbReference type="KEGG" id="vg:1486746"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000248">
        <property type="entry name" value="ATII_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00241">
        <property type="entry name" value="ANGIOTENSINR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0297">G-protein coupled receptor</keyword>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-1032">Host cell membrane</keyword>
    <keyword id="KW-1043">Host membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0675">Receptor</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0807">Transducer</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000070249" description="G-protein coupled receptor homolog FPV027">
        <location>
            <begin position="1"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="topological domain" description="Extracellular" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=1" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=2" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="topological domain" description="Extracellular" evidence="1">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=3" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=4" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="topological domain" description="Extracellular" evidence="1">
        <location>
            <begin position="165"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=5" evidence="1">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=6" evidence="1">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="topological domain" description="Extracellular" evidence="1">
        <location>
            <begin position="262"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Name=7" evidence="1">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="1">
        <location>
            <begin position="298"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine; by host" evidence="1">
        <location>
            <position position="5"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine; by host" evidence="1">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="99"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="336" mass="38991" checksum="434095D954A5E293" modified="2000-10-01" version="1">MSMNNITSKMNQDSYGYFQLHMSDFTRVSLSIVFTLVFLVGIIGNAVIIWFIGFKWTKTISTLLFINLALADSLFLIFIPVYTVYVLSNFHWYLGEFLCRVSSFFFTTNMYASMFLLTFISIDKYLTLTSHRLVYKYRKYRNYYVCIGAIWCISIALGVPTLYYKRVILSSSRNETRCISYYGDDKHTAITIYRIIVCIRFIIGYVFPMTVILLSYALIVYKVKFINKPPNRSFMITTASIFVFLACWTPHHVLNIISLYGLKSTSMYNYIKESIPFVNAIAFVYSAINPIIYIFVIRLTSTYDSDTMDELRSALLDEETTSTEDCSDIEISDISR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5H8</accession>
    <name>V023_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV023</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV023</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038986.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5H8"/>
    <dbReference type="GeneID" id="1486742"/>
    <dbReference type="KEGG" id="vg:1486742"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067106" description="Putative ankyrin repeat protein FPV023">
        <location>
            <begin position="1"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="33"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="134"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="167"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="201"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="236"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 6">
        <location>
            <begin position="269"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 7">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <sequence length="434" mass="48885" checksum="139BDB7296322E57" modified="2000-10-01" version="1">MDYTKITRYTTGIDSILYKLIENCIDLRPTTYRLKILLHKAIELRNIEAVRLLLNNDVDPVAIDTHGITSLHTLTMPPNSSFIELDNWCSNTYTELLEVINRLNKSKTSYSFQRVELMRMIMDYCKDDEISKCLTISRMEPSRQIEEIQIMDILLSKGIDINFKDDIGNTALHYACDYRNGLNMVRHLIKNGADINIENDYGTTPLACAVSTRNIELVSILLDSGADPNSSSSSSIGTKVLHTAVGSGNFNIAKELIESGADPNIGDKAGVTPLHVAAIDEDSYALLELLLDNGADPNIKCSNGTTPLFQAMHNYNRVKLLFMYGADINIIDNQGNTPFTNLMSYDNEKLNSIIILQIMLIRKLFNDKMYYPAGLIKNLECIESHENLMNMAKRCEKLIKNKKSKDIVPDRISSELLDEEYDLDGWRSTSCSIS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5I3</accession>
    <name>V018_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV018</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV018</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038981.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5I3"/>
    <dbReference type="GeneID" id="1486737"/>
    <dbReference type="KEGG" id="vg:1486737"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018272">
        <property type="entry name" value="PRANC_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09372">
        <property type="entry name" value="PRANC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067104" description="Putative ankyrin repeat protein FPV018">
        <location>
            <begin position="1"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="126"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="204"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="236"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 6">
        <location>
            <begin position="270"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 7">
        <location>
            <begin position="301"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 8">
        <location>
            <begin position="395"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 9">
        <location>
            <begin position="428"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 10">
        <location>
            <begin position="461"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 11">
        <location>
            <begin position="494"/>
            <end position="523"/>
        </location>
    </feature>
    <sequence length="700" mass="80698" checksum="A36FB71A13A84CF0" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5I5</accession>
    <name>Q9J5I5_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV016</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV016</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038979.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486735"/>
    <dbReference type="KEGG" id="vg:1486735"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="238" mass="27320" checksum="77FAD7976300451C" modified="2000-10-01" version="1">MKMNYMVIAIAIIISFILKNIYGEEDLPDSPVKLQCRTKDGDEISRATWRGDDNIMVAQEQVGGYGLNAFNYVPGPYKDMYEVTVSGSTSTFTVKKPDPQSLCFTCVLRTASGKEETYQRCTEIQKEDITYVVEKHRNETTITCFVGSKHGDPRWIVTGIVTGGVMSYEIPRGFTQNVEYYRYTSIKVNESVVGHVETPYCRYWINNTHAREFPVHYVGKEQGKEYIVTEYKDVYGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5I8</accession>
    <name>Q9J5I8_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV013</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV013</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038976.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486732"/>
    <dbReference type="KEGG" id="vg:1486732"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="60" mass="7140" checksum="C7C02F6BB5EC7215" modified="2000-10-01" version="1">MKTRVTTDWYPSHMDLVIIKSNEAIELLNSYPDQDKSRRKKELHNAITLDNNTTPLRWKL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5I9</accession>
    <name>V012_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV012</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV012</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038975.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5I9"/>
    <dbReference type="GeneID" id="1486731"/>
    <dbReference type="KEGG" id="vg:1486731"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018272">
        <property type="entry name" value="PRANC_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09372">
        <property type="entry name" value="PRANC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067102" description="Putative ankyrin repeat protein FPV012">
        <location>
            <begin position="1"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="11"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="110"/>
            <end position="139"/>
        </location>
    </feature>
    <sequence length="331" mass="37301" checksum="A8403E37517C5901" modified="2000-10-01" version="1">MDTEMDGVNNDGYTSLYKETAKGNIKKVVELLYKGVNPNTPNVDSYTPLHIAAKTGNIKIIRRLIRYGANVDKETNDGYTALLIAICTGDIKTCNVLLDEGANPNYVNKYGITPLVRIISYYRPTILKLLMDRGANCNQIINIGQVTYTIMEYFINLFDEYKIPILNLVPYIIISKFKASITVNIEGFNRNIAAIAKNSRLLEVALKCKSEIAFMTTRGIGDKSLFEICILEDIKDIDHNSFVAFLDKLIESQSNLRIYGYTMNKIIEMGRYRKELLCSAVRVNSCNLSSLNTEWCLLPLKGKLNILSKLNNDNIKKLILNDAIKVNNKTG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-08-12" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5J1</accession>
    <name>V010_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized serpin-like protein FPV010</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV010</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the serpin family. Poxviruses subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038973.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5J1"/>
    <dbReference type="GeneID" id="1486729"/>
    <dbReference type="KEGG" id="vg:1486729"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="PTHR11461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="SSF56574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0646">Protease inhibitor</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="chain" id="PRO_0000094154" description="Uncharacterized serpin-like protein FPV010">
        <location>
            <begin position="1"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="355" mass="40617" checksum="D3EDFB65E5CABABF" modified="2000-10-01" version="1">MGSLVRLLKELYVPGKDICISPRGVYTILMNIMIGCKKETRDKIKDLLGIFGNYVPIPDKSEYYVEYYDDKDELINKSIMLIEEGYPIKRDFINSSYDIFNAKVVSFTDDTISETINKWVELSTRGLIKDFSISLADDIRLAIINVLYFKSKWKYPFDTELTSKHPFKKYNGTDVMIDTMMIQDVAFYYKHDEDIRSQVVMLEYEDYRFVMFIIIPDSVTGIDGVVDSLNNGKNINKIISKKDMTLKEIVLYLPKFELEDDVDLKDALIHMGCNDLFKSGELVGISDTKTLRIGNIRQKSVIKVDEYGTEAASVTESCTTDGIKKIPIVKANVPFMFLVADVQTKIPLFLGIFQG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-08-12" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>Q9YPJ6</accession>
    <name>V238_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein FPV238</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>ORF f</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV238</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1025" last="1040">
            <title>Sequence analysis of an 11.2 kilobase, near-terminal, BamHI fragment of fowlpox virus.</title>
            <authorList>
                <person name="Tomley F."/>
                <person name="Binns M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E."/>
            </authorList>
            <dbReference type="PubMed" id="2836548"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="JT0460">
        <property type="entry name" value="JT0460"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039202.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9YPJ6"/>
    <dbReference type="GeneID" id="1486810"/>
    <dbReference type="KEGG" id="vg:1486810"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0244">Early protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099734" description="Uncharacterized protein FPV238">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <sequence length="61" mass="7461" checksum="40328C83CD56CEC2" modified="1999-05-01" version="1">MESTSIILRYYVAVYPPPFFKYTLSRFIKLKNAFKLLIIKLKKQIMIYREVLNTYIIQWIV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-08-12" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>Q9YPK0</accession>
    <name>V009_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein FPV009/FPV252</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>ORF b</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV009</name>
    </gene>
    <gene>
        <name type="ordered locus">FPV252</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1025" last="1040">
            <title>Sequence analysis of an 11.2 kilobase, near-terminal, BamHI fragment of fowlpox virus.</title>
            <authorList>
                <person name="Tomley F."/>
                <person name="Binns M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E."/>
            </authorList>
            <dbReference type="PubMed" id="2836548"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="D00295">
        <property type="protein sequence ID" value="BAA00193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="JT0456">
        <property type="entry name" value="JT0456"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038972.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039215.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486829"/>
    <dbReference type="GeneID" id="1486841"/>
    <dbReference type="KEGG" id="vg:1486829"/>
    <dbReference type="KEGG" id="vg:1486841"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0244">Early protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099726" description="Uncharacterized protein FPV009/FPV252">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <sequence length="66" mass="7791" checksum="F6BF3B90CA85AFA8" modified="1999-05-01" version="1">MNKALMIFVYYLTRVTLSKCLVYFTKERYVLKKIDTPIGIPNTCVRFTTSFLYNSILYVLVNRKSV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>O72896</accession>
    <name>O1_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein O1 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Protein FPV091</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV091</name>
        <name type="ORF">FPO1L</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1998" name="Virus Genes" volume="17" first="5" last="9">
            <title>Nucleotide sequence of the 4.3 kbp BamHI-N fragment of fowlpox virus FP9.</title>
            <authorList>
                <person name="Pollitt E."/>
                <person name="Skinner M.A."/>
                <person name="Heaphy S."/>
            </authorList>
            <dbReference type="PubMed" id="9778782"/>
            <dbReference type="DOI" id="10.1023/A:1008045914991"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae O1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AJ223385">
        <property type="protein sequence ID" value="CAA11289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039054.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="O72896"/>
    <dbReference type="GeneID" id="1486639"/>
    <dbReference type="KEGG" id="vg:1486639"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021155">
        <property type="entry name" value="Poxvirus_E2/O1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006732">
        <property type="entry name" value="Poxvirus_O1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04497">
        <property type="entry name" value="Pox_E2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015980">
        <property type="entry name" value="VAC_O1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000099641" description="Protein O1 homolog">
        <location>
            <begin position="1"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="544"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="656" mass="77178" checksum="274E70D4E26A6456" modified="1998-08-01" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>O90758</accession>
    <name>V033_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Soluble NSF attachment protein homolog FPV033</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">SNAP</name>
        <name type="ordered locus">FPV033</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1998" name="J. Virol." volume="72" first="6742" last="6751">
            <title>Fowlpox virus encodes nonessential homologs of cellular alpha-SNAP, PC-1, and an orphan human homolog of a secreted nematode protein.</title>
            <authorList>
                <person name="Laidlaw S.M."/>
                <person name="Anwar M.A."/>
                <person name="Thomas W."/>
                <person name="Green P."/>
                <person name="Shaw K."/>
                <person name="Skinner M.A."/>
            </authorList>
            <dbReference type="PubMed" id="9658122"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNAP family.</text>
    </comment>
    <dbReference type="EMBL" id="AJ006408">
        <property type="protein sequence ID" value="CAA07011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038996.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="O90758"/>
    <dbReference type="GeneID" id="1486752"/>
    <dbReference type="KEGG" id="vg:1486752"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="CDD" id="cd15832">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="PTHR13768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00448">
        <property type="entry name" value="NSFATTACHMNT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0653">Protein transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000219078" description="Soluble NSF attachment protein homolog FPV033">
        <location>
            <begin position="1"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="287" mass="33438" checksum="66EC241841AABA5F" modified="1998-11-01" version="1">MEQEAYRLISEANRRLKDVGFLFSWKFLRNVNNVKEVGNLLIRSAILFKAVKNWELAGYSFLKAAVLQSQESDFVLDTAINFVNASNMYRKIDPKKSIECLLQAIEVYKSINNFTTAAKHQMTVAEIYESCIMDLEKACMHYEYATEYYREEGSIKSANDCMIKVADCFTRMKQFDKAASVYEQIGIICMRLPILKHRIKDQFLKAILCHFCIGDKDMRLIVGYYTELYAQFIDYREYTLIMKVVESCDTCNLDILVDALREYGSVTRLDYILTIMLLEIKKNIQTQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2019-10-16" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>P0DTA7</accession>
    <accession>Q70H53</accession>
    <accession>Q9J5B8</accession>
    <name>PAP1_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Poly(A) polymerase catalytic subunit</fullName>
            <ecNumber>2.7.7.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Poly(A) polymerase large subunit</fullName>
            <shortName>PAP-L</shortName>
        </alternativeName>
        <alternativeName>
            <fullName>VP55</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">PAPL</name>
        <name type="ordered locus">FPV102</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text>Polymerase that creates the 3'-poly(A) tail of mRNA's.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide</text>
            <dbReference type="Rhea" id="RHEA:11332"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17347"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="ChEBI" id="CHEBI:173115"/>
            <dbReference type="EC" id="2.7.7.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of a large (catalytic) subunit and a small (regulatory) subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviridae poly(A) polymerase catalytic subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039065.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P0DTA7"/>
    <dbReference type="GeneID" id="1486650"/>
    <dbReference type="KEGG" id="vg:1486650"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037265">
        <property type="entry name" value="PolyA_pol_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024231">
        <property type="entry name" value="Pox_polyA_pol_nucTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038419">
        <property type="entry name" value="Pox_polyA_pol_nucTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004976">
        <property type="entry name" value="Poxviridae_polyA_pol_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024397">
        <property type="entry name" value="Poxvirus_polyA_pol_cat_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024398">
        <property type="entry name" value="Poxvirus_polyA_pol_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038337">
        <property type="entry name" value="Poxvirus_polyA_pol_cat_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03296">
        <property type="entry name" value="Pox_polyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12629">
        <property type="entry name" value="Pox_polyA_pol_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12630">
        <property type="entry name" value="Pox_polyA_pol_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015693">
        <property type="entry name" value="VAC-48L_nuct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160957">
        <property type="entry name" value="SSF160957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000099109" description="Poly(A) polymerase catalytic subunit">
        <location>
            <begin position="1"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="472" mass="56081" checksum="ADDD6F39EC84DC22" modified="2019-10-16" version="1">MERSRQVYYIINEYLGRHPSSTEYQVLKHQVEKISKINNFNKETFFFLLKKNKNKFFKDLELSDDLLKKRIDEYFSKQKHAKRLGNLFAIMELQKILISSFTKTIGILTTKVPEYYHSTIKLEYSSMEKIADDILDSYNVVEPSKEVKGRHKVSDLVGHVYKIMEEYLRRHSNSCLCYGSYSLHFLNNKIEYGDIDVLQTNARTFLINIAFLIKFITGRRIVLLKVPFLKNYVIMHDEETNHVMDTFNIREKTMNMIPKIMIDNMYIVDPCIQLLNMIKMLSQIDRLEELQAKFEKLSVRLGTLLEYTRYRYSIPLDSESILEVRAKLDKDKRKITVDFKKYKLNYIKCYFYLDEVELKKFISKNSGLDEYEDFEAVTNSEYAIRNKTMYTYFSNTALMRSENEIHPITINALTSHALLYHVITRKFYDDLLGDLVRSLMIVEKVPVFKIIPRDKKQGRHTIIDIEKDIIFH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2019-10-16" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>P0DTA9</accession>
    <accession>Q70H83</accession>
    <accession>Q9J5E2</accession>
    <name>D3_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>27 kDa core protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV069</name>
        <name type="ordered locus">fp9.069</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Late protein which is part of a large complex required for early virion morphogenesis. This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Localizes to the virion core.</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae D3 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039032.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486617"/>
    <dbReference type="KEGG" id="vg:1486617"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007660">
        <property type="entry name" value="Pox_D3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04580">
        <property type="entry name" value="Pox_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099435" description="27 kDa core protein">
        <location>
            <begin position="1"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="270" mass="31962" checksum="9D1578339992F8A8" modified="2019-10-16" version="1">MEIHRLNSYTSVDYLCNSSNNVYILLGDTDEFINKRIILLMNNIELYYVYEISVNDEDELYHSFITSNVVCPIKQRINLMLYKEYKKVIGSCVINNEGNIKMYSQPDKLHVYVLCYRCNGDIKTITMIKCHQLLKPEKEIVIDGYQVNDSSFFYTSPNLIKQINMDKSDLFYKNILLRKEINCLIRKQESSNLYCILNKHIVSLSDTDIWKVIISDELFDSSDIEKLVKFDYDRDKFHAFVRAWYSGQLSNCKEENETIKTVYEMIEKRI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2019-10-16" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>P0DTB1</accession>
    <accession>P15909</accession>
    <accession>Q70H31</accession>
    <accession>Q9J596</accession>
    <name>V127_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein FPV127</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV127</name>
        <name type="ordered locus">fp9.127</name>
        <name type="ORF">FP1</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviruses A16/G9/J5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44394.1"/>
        <property type="status" value="ALT_SEQ"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039013.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486598"/>
    <dbReference type="KEGG" id="vg:1486598"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004251">
        <property type="entry name" value="Pox_virus_G9/A16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03003">
        <property type="entry name" value="Pox_G9-A16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099545" description="Protein FPV127">
        <location>
            <begin position="1"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="336" mass="38045" checksum="CBCFC3BCDBA4C202" modified="2019-10-16" version="1">MGGGLVLPTRDPPKEQDTSETATNIPKLLKSIPGVKLGQQIRIGYKPGPETAKAFPEFDIKEVSNGLYELSRKSYLGDTKTCCINPSLSYYWEDSKNKIFDEYATGRSLKTCDPLTKTISGSTLCDNILTSLCLDEKSGVDRTMCNEWMGYALNRPDLSIPKSINDRYTKLCSKGANNIVCEDWLHHLRIIGGKENDEVIDNVLMQQTPEFKEKYMKCSFPSHNTVFLADRVIEPRECWDQECITSNVHFLLSKNYHNLTLCHIYRCNISINNLLIDGKSSVKISCHDENISNKDKPKARNKAKFIDDILGSSFNINFGFFFVIFIMIALILIVLL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-04-01" modified="2020-12-02" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>P15908</accession>
    <name>VLTF1_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Late transcription factor 1</fullName>
            <shortName>VLTF-1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">VLTF1</name>
        <name type="ordered locus">FPV126</name>
        <name type="ORF">FP0</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1275" last="1283">
            <title>Comparison of a conserved region in fowlpox virus and vaccinia virus genomes and the translocation of the fowlpox virus thymidine kinase gene.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Tomley F.M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2838574"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-444</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Associates with RNA polymerase to initiate transcription from late gene promoters.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with the late transcription factors VLTF-2 and VLTF-3. Interacts with the late transcription elongation factor H5/VLTF-4. Interacts with itself.</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the intermediate phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae VLTF-1 family.</text>
    </comment>
    <dbReference type="EMBL" id="D00320">
        <property type="protein sequence ID" value="BAA00223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="JS0220">
        <property type="entry name" value="WMVZP0"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039089.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486674"/>
    <dbReference type="KEGG" id="vg:1486674"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005022">
        <property type="entry name" value="Pox_TAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03355">
        <property type="entry name" value="Pox_TAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0010">Activator</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <feature type="chain" id="PRO_0000099169" description="Late transcription factor 1">
        <location>
            <begin position="1"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="260" mass="29853" checksum="E8CBDCA7EBA9869F" modified="1990-04-01" version="1">MSLRIKIDKLRQLVTYFSEFSEEVSINIDVKSNVLYIFATLGGSINIWTIVPLNSNVFYNGVENTVFNLPVLKVKNCLCSFHNDAVVSITADHDNNTVTLSSHYTVSIDCNNEQIPHSTGTSISLGIDQKKSYIFNFHKYEEKCCGRTVFHLDMLLGFIKCISQYQYLNICFDDKKLLLKTPGTRDTFVRSYSMTEWSPTLQNYSFKIAIFSLNKLRGFKKRVLVFESKIVMDTEGNILGLLFRDRIGTYKVNVFMAFQD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-04-01" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>P15914</accession>
    <name>L5_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>L5 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Protein FPV132</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV132</name>
        <name type="ORF">FP6</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1275" last="1283">
            <title>Comparison of a conserved region in fowlpox virus and vaccinia virus genomes and the translocation of the fowlpox virus thymidine kinase gene.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Tomley F.M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2838574"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-444</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1987" name="Virology" volume="160" first="203" last="209">
            <title>Similar genetic organization between a region of fowlpox virus DNA and the vaccinia virus HindIII J fragment despite divergent location of the thymidine kinase gene.</title>
            <authorList>
                <person name="Drillien R."/>
                <person name="Spehner D."/>
                <person name="Villeval D."/>
                <person name="Lecocq J.-P."/>
            </authorList>
            <dbReference type="PubMed" id="2820129"/>
            <dbReference type="DOI" id="10.1016/0042-6822(87)90061-4"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>Salisbury</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry. Also plays a role in cell-cell fusion (syncytium formation).</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of a stable entry-fusion complex (EFC) which is at least composed of proteins A16, A21, A28, G3, G9, H2, J5, and L5. Formation of the viral membrane is necessary for the assembly of the complex. Interacts with G3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion membrane</location>
            <topology evidence="3">Single-pass type III membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">Component of the mature virion (MV) membrane (By similarity). The mature virion is located in the cytoplasm of infected cells and is probably released by cell lysis.</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Most cysteines are linked by disulfide bonds. They are created by the viral disulfide bond formation pathway, a poxvirus-specific redox pathway that operates on the cytoplasmic side of the MV membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the chordopoxvirinae L5 family.</text>
    </comment>
    <dbReference type="EMBL" id="D00320">
        <property type="protein sequence ID" value="BAA00229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="M17418">
        <property type="protein sequence ID" value="AAA66420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="JS0226">
        <property type="entry name" value="WMVZP6"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039095.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P15914"/>
    <dbReference type="GeneID" id="1486680"/>
    <dbReference type="KEGG" id="vg:1486680"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019031">
        <property type="term" value="C:viral envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055036">
        <property type="term" value="C:virion membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019064">
        <property type="term" value="P:fusion of virus membrane with host plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046718">
        <property type="term" value="P:viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006956">
        <property type="entry name" value="Poxvirus_L5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04872">
        <property type="entry name" value="Pox_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-1169">Fusion of virus membrane with host cell membrane</keyword>
    <keyword id="KW-1168">Fusion of virus membrane with host membrane</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0735">Signal-anchor</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0261">Viral envelope protein</keyword>
    <keyword id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <keyword id="KW-1160">Virus entry into host cell</keyword>
    <feature type="chain" id="PRO_0000099629" description="L5 homolog">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical; Signal-anchor for type III membrane protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="76"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="129" mass="14745" checksum="DB98CCC282E48A6B" modified="1990-04-01" version="1">MDRNINFSPVFIEPRFKHEFLLSPQRYFYILVFEVIVALIILNFFFKEEILYTFFPLAKPSKNSINSLLDRTMLKCEEDGSLMISRPSGIYSALSLDGSPVRISDCSLLLSSINGASSSTSPYSIFNRR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1990-04-01" modified="2022-02-23" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>P15915</accession>
    <name>J1_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein J1 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>Protein FPV133</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">FPV133</name>
        <name type="ORF">FP7</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1988" name="J. Gen. Virol." volume="69" first="1275" last="1283">
            <title>Comparison of a conserved region in fowlpox virus and vaccinia virus genomes and the translocation of the fowlpox virus thymidine kinase gene.</title>
            <authorList>
                <person name="Binns M.M."/>
                <person name="Tomley F.M."/>
                <person name="Campbell J."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="2838574"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-444</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1987" name="Virology" volume="160" first="203" last="209">
            <title>Similar genetic organization between a region of fowlpox virus DNA and the vaccinia virus HindIII J fragment despite divergent location of the thymidine kinase gene.</title>
            <authorList>
                <person name="Drillien R."/>
                <person name="Spehner D."/>
                <person name="Villeval D."/>
                <person name="Lecocq J.-P."/>
            </authorList>
            <dbReference type="PubMed" id="2820129"/>
            <dbReference type="DOI" id="10.1016/0042-6822(87)90061-4"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>Salisbury</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Late protein which is a part of a large complex required for early virion morphogenesis. This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions. J1 protein is required for DNA packaging during immature virions (IV) formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Part of a complex composed of A30, G7, F10 kinase, A15, D2, D3, and J1. Interacts with A45.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location>Virion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Host cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">Localizes in cytoplasmic virus factories. Probably located in between the core and the virion membrane (By similarity).</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae J1 family.</text>
    </comment>
    <dbReference type="EMBL" id="D00320">
        <property type="protein sequence ID" value="BAA00230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="M17418">
        <property type="protein sequence ID" value="AAA66421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="JS0227">
        <property type="entry name" value="WMVZP7"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039096.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486681"/>
    <dbReference type="KEGG" id="vg:1486681"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005006">
        <property type="entry name" value="Poxvirus_J1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03338">
        <property type="entry name" value="Pox_J1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-1035">Host cytoplasm</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099590" description="Protein J1 homolog">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="148" mass="16953" checksum="4EF42F906079CDF4" modified="1990-04-01" version="1">MAHPHQHLLTLFLTDDNGFYSYLSEKSDDEALEDINTIKKYMDFILSVLIRSKEKLENIGCSYEPMSESFKALIKVKDDGTLVKAFTKPLLNPHSEKIVLDRGYTSDFAISVIRLSSKSSYILPANTKYINPNENMYINNLISLLKRN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1991-08-01" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>P21967</accession>
    <accession>O93018</accession>
    <name>RP18_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>DNA-directed RNA polymerase 18 kDa subunit</fullName>
            <ecNumber>2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">RPO18</name>
        <name type="ordered locus">FPV056</name>
        <name type="ORF">FP-D7</name>
        <name type="ORF">FPD7</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1990" name="J. Gen. Virol." volume="71" first="1517" last="1524">
            <title>Nucleotide sequence analysis of a 10.5 kbp HindIII fragment of fowlpox virus: relatedness to the central portion of the vaccinia virus HindIII D region.</title>
            <authorList>
                <person name="Tartaglia J."/>
                <person name="Winslow J."/>
                <person name="Goebel S.J."/>
                <person name="Johnson G.P."/>
                <person name="Taylor J."/>
                <person name="Paoletti E."/>
            </authorList>
            <dbReference type="PubMed" id="2165135"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-1</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="submission" date="1998-05" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Skinner M.A."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-440</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. DNA-dependent RNA polymerase associates with the early transcription factor (ETF) thereby allowing the early genes transcription. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The DNA-dependent RNA polymerase used for intermediate and late genes expression consists of eight subunits 147 kDa, 133 kDa, 35 kDa, 30 kDa, 22 kDa, 19 kDa, 18 kDa and 7 kDa totalling more than 500 kDa in mass. The same holoenzyme, with the addition of the transcription-specificity factor RAP94, is used for early gene expression.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Virion</location>
        </subcellularLocation>
        <text evidence="1">All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the early phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviridae DNA-directed RNA polymerase 18 kDa subunit family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="CAA06398" version="1"/>
        </conflict>
        <text>Truncated N-terminus.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="CAA06398" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="2.7.7.6"/>
    <dbReference type="EMBL" id="X17202">
        <property type="protein sequence ID" value="CAA35070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AJ005163">
        <property type="protein sequence ID" value="CAA06398.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="G35216">
        <property type="entry name" value="G35216"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039019.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P21967"/>
    <dbReference type="GeneID" id="1486604"/>
    <dbReference type="KEGG" id="vg:1486604"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019083">
        <property type="term" value="P:viral transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004973">
        <property type="entry name" value="DNA-dir_RNA_pol_18kDa_poxviral"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03293">
        <property type="entry name" value="Pox_RNA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0244">Early protein</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099154" description="DNA-directed RNA polymerase 18 kDa subunit">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="161" mass="18014" checksum="4C1752A43CB6D3BD" modified="1991-08-01" version="1">MSLFNTNAYLPVVIQPHELNLDLMDNIKKAVINKYLHKETSGFMAKKIQIVEDTPMPLAELVNNEIVVHVTCNIDYKYYKVGDIVSGILTITDESDISVVCSDLICKIRSDSGTVSYDNSKYCFIKNGKVYANESTVTVMLKEAQSGMESSFVFLGNIIEK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1991-08-01" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>P21970</accession>
    <accession>Q9J5F3</accession>
    <name>D9_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative Nudix hydrolase FPV054</fullName>
            <ecNumber>3.6.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV054</name>
        <name type="ORF">FP-D9</name>
        <name type="ORF">FPD9</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1990" name="J. Gen. Virol." volume="71" first="1517" last="1524">
            <title>Nucleotide sequence analysis of a 10.5 kbp HindIII fragment of fowlpox virus: relatedness to the central portion of the vaccinia virus HindIII D region.</title>
            <authorList>
                <person name="Tartaglia J."/>
                <person name="Winslow J."/>
                <person name="Goebel S.J."/>
                <person name="Johnson G.P."/>
                <person name="Taylor J."/>
                <person name="Paoletti E."/>
            </authorList>
            <dbReference type="PubMed" id="2165135"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-78</scope>
        <source>
            <strain>FP-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Decapping enzyme required for the removal of the 5'-end m7GpppN cap tethered to viral and host mRNAs to allow their decay in cells. May therefore accelerate viral and cellular mRNA turnover to eliminate competing host mRNAs and allow stage-specific synthesis of viral proteins. Acceleration of the turnover of cellular transcripts may even promote the shutoff of host protein synthesis. Does not cleave unmethylated RNAs or RNAs shorter than 24 nucleotides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="induction">
        <text>Expressed in the early phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.-.-"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="X17202">
        <property type="protein sequence ID" value="CAA35072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039017.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486602"/>
    <dbReference type="KEGG" id="vg:1486602"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003300">
        <property type="entry name" value="Viral_VD9"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01363">
        <property type="entry name" value="VD09PROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0235">DNA replication</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000057090" description="Putative Nudix hydrolase FPV054">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="74"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Nudix box">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="231" mass="27267" checksum="B2337D8128761DFD" modified="2001-08-29" version="2">MFDISREQQNMLEKNKDCVITFETNRERITIENTNIKDILSDRRIHIFALCITSDNIPIIGIRRTSFMYQSVISKRRSFSEILAVDINHLKYMYNNEIKEICIRSIVPFTYSGFNNFEELVLLGGRVKNKESIYQCLSRELSEESDGILTIKTFGNKILKLTIEDKILRRTFYGYCIVCFIDQLYSEIIKPLYNIEIKELGSLFDRSSNEKYEYLHFIYNTLLTYKYGGVL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1991-08-01" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>P21974</accession>
    <name>DCK1_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Probable deoxycytidine kinase FPV059</fullName>
            <shortName>dCK</shortName>
            <ecNumber>2.7.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV059</name>
        <name type="ORF">FP26</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1990" name="J. Gen. Virol." volume="71" first="1517" last="1524">
            <title>Nucleotide sequence analysis of a 10.5 kbp HindIII fragment of fowlpox virus: relatedness to the central portion of the vaccinia virus HindIII D region.</title>
            <authorList>
                <person name="Tartaglia J."/>
                <person name="Winslow J."/>
                <person name="Goebel S.J."/>
                <person name="Johnson G.P."/>
                <person name="Taylor J."/>
                <person name="Paoletti E."/>
            </authorList>
            <dbReference type="PubMed" id="2165135"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-1</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="1993" name="Virus Genes" volume="7" first="289" last="295">
            <title>Fowlpox virus encodes a protein related to human deoxycytidine kinase: further evidence for independent acquisition of genes for enzymes of nucleotide metabolism by different viruses.</title>
            <authorList>
                <person name="Koonin E.V."/>
                <person name="Senkevich T.G."/>
            </authorList>
            <dbReference type="PubMed" id="8279127"/>
            <dbReference type="DOI" id="10.1007/BF01702589"/>
        </citation>
        <scope>DISCUSSION OF SEQUENCE</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction>
            <text>2'-deoxycytidine + a ribonucleoside 5'-triphosphate = a ribonucleoside 5'-diphosphate + dCMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="EC" id="2.7.1.74"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DCK/DGK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.74"/>
    <dbReference type="EMBL" id="X17202">
        <property type="protein sequence ID" value="CAA35067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="D35216">
        <property type="entry name" value="D35216"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039022.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="P21974"/>
    <dbReference type="PRIDE" id="P21974"/>
    <dbReference type="GeneID" id="1486607"/>
    <dbReference type="KEGG" id="vg:1486607"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004137">
        <property type="term" value="F:deoxycytidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01673">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002624">
        <property type="entry name" value="DCK/DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031314">
        <property type="entry name" value="DNK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01712">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000705">
        <property type="entry name" value="DNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000175093" description="Probable deoxycytidine kinase FPV059">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="16"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="219" mass="25909" checksum="4C3B08D885B58CE7" modified="1991-08-01" version="1">MDSINEFTSKKLSIEGNISSGKTDVLNILRNINNVVSFHDVEDRYTPIEKELIRKFHENPSRWSYALQTHYCMKRVRMHLECFVPSRVNILERSIFSDRYVFAEAATALGYMDDPEWALYCKQHDWYTDKLEIQFDGIIYLRTIPESCKERINEKSITEKNYPNISIDYLKTLHEKHELWLTQCKKVPVLIIDGEEDFIFDPCAKKKLINEVTEFINSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-07-27" modified="2021-06-02" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>Q77NT0</accession>
    <name>Q77NT0_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV088 DNA-binding phosphoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV088</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="A48563">
        <property type="entry name" value="A48563"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039051.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486636"/>
    <dbReference type="KEGG" id="vg:1486636"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006754">
        <property type="entry name" value="Poxvirus_I3_ssDNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04661">
        <property type="entry name" value="Pox_I3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="290" mass="33150" checksum="E33422678B4B9FC9" modified="2011-07-27" version="1">MKNNLYEEKMNMSKKQVKTQSKCNNNASRFTCLDAVQYAKALCTKDTKIVKSVKLTPSHHNLCSNISVTLEPKYNEKLVSPFILVEGEGKIYQTRSDNFSREESYFLKIRPSVISPILHQMMECIYSDLGYLDPENTMDEKTFKDGYIYINKNKMSSTIIEYTRNNKEVAGRKTLSSEVEHLSKKDPQMVKAVLVASIFFENAVMCKISFSLKKLIMEKVCRKTLIDTNGEVISVVTSGDDDIEDESGEFEYESDGVSGILEERSDGNRRGGYKIKETDEYDERSLFNVN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>Q85280</accession>
    <name>RP22_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>DNA-directed RNA polymerase 22 kDa subunit</fullName>
            <ecNumber>2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">RPO22</name>
        <name type="ordered locus">FPV135</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1987" name="Virology" volume="160" first="203" last="209">
            <title>Similar genetic organization between a region of fowlpox virus DNA and the vaccinia virus HindIII J fragment despite divergent location of the thymidine kinase gene.</title>
            <authorList>
                <person name="Drillien R."/>
                <person name="Spehner D."/>
                <person name="Villeval D."/>
                <person name="Lecocq J.-P."/>
            </authorList>
            <dbReference type="PubMed" id="2820129"/>
            <dbReference type="DOI" id="10.1016/0042-6822(87)90061-4"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>Salisbury</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of early, intermediate and late genes. DNA-dependent RNA polymerase associates with the early transcription factor (ETF) thereby allowing the early genes transcription. Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The DNA-dependent RNA polymerase used for intermediate and late genes expression consists of eight subunits 147 kDa, 133 kDa, 35 kDa, 30 kDa, 22 kDa, 19 kDa, 18 kDa and 7 kDa totalling more than 500 kDa in mass. The same holoenzyme, with the addition of the transcription-specificity factor RAP94, is used for early gene expression.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Virion</location>
        </subcellularLocation>
        <text evidence="1">All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the poxviridae DNA-directed RNA polymerase 22 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6"/>
    <dbReference type="EMBL" id="M17418">
        <property type="protein sequence ID" value="AAA66423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039098.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q85280"/>
    <dbReference type="GeneID" id="1486683"/>
    <dbReference type="KEGG" id="vg:1486683"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019083">
        <property type="term" value="P:viral transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007937">
        <property type="entry name" value="RNA_Pol_22kDa_poxvir"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05273">
        <property type="entry name" value="Pox_RNA_Pol_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000744">
        <property type="entry name" value="RPO22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099142" description="DNA-directed RNA polymerase 22 kDa subunit">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="186" mass="21800" checksum="584BD653E120FD97" modified="1996-11-01" version="1">MMNQYNVTYLSKILCLKTEILYKPFSIINRSIVNQYNIDVKYDDITSIVKIRHKTENTILVFQIFNESNVKYSPIEYDYGDPIIITSNLQHGHNRIPINMLYIDVVESDMFPTFSRLDSETIKIITSILQSDNKKEQSIKLPKVSENELSVKILYHKDYPLKYVRYYKNNMVTGIEVIDRSVAITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>Q9ICC7</accession>
    <name>Q9ICC7_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV004</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein FPV257</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV257</name>
        <name evidence="1" type="synonym">FPV004</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="D31685">
        <property type="entry name" value="D31685"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038967.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039220.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486826"/>
    <dbReference type="GeneID" id="1486839"/>
    <dbReference type="KEGG" id="vg:1486826"/>
    <dbReference type="KEGG" id="vg:1486839"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="101" mass="11529" checksum="BC037D295EFE6108" modified="2000-10-01" version="1">MNNDTIFTLFYCKNKKYVRGEGGRRRGKTGILLFHPINHRVIGTSAHQCYKTRRIGFKLYAVAPRHVSTIRCGRSHSAHRVDKFSFSFQKVDFHCIAGSGA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J505</accession>
    <name>V230_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV230</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV230</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039193.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J505"/>
    <dbReference type="GeneID" id="1486802"/>
    <dbReference type="KEGG" id="vg:1486802"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067121" description="Putative ankyrin repeat protein FPV230">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="2"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="36"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="135"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <sequence length="188" mass="21493" checksum="894A7895A22DF3C6" modified="2000-10-01" version="1">MENELKLYYAVSSQNENLVIQLLNKGYNPNAINRFKYMIPLHKAVECRNVDITKHLLSNGADANVRDFLGLGVFHILSMFSSLPELKDILHNTEGTFVLCKYNYAPLEEDYEVKTLEIARMLFISKANINMTSKLGSTPLHIASKYNNKTMVKFFLERGADINILDSNNNTPLIYAVCSVIRLYLKCY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J507</accession>
    <name>V228_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV228</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV228</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039191.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J507"/>
    <dbReference type="GeneID" id="1486800"/>
    <dbReference type="KEGG" id="vg:1486800"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018272">
        <property type="entry name" value="PRANC_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09372">
        <property type="entry name" value="PRANC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067120" description="Putative ankyrin repeat protein FPV228">
        <location>
            <begin position="1"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="39"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="72"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="123"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="190"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 6">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 7">
        <location>
            <begin position="258"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 8">
        <location>
            <begin position="291"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 9">
        <location>
            <begin position="324"/>
            <end position="353"/>
        </location>
    </feature>
    <sequence length="525" mass="60156" checksum="E8AF61D9B33BCFB0" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J512</accession>
    <name>V223_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV223</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV223</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039186.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J512"/>
    <dbReference type="GeneID" id="1486795"/>
    <dbReference type="KEGG" id="vg:1486795"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067117" description="Putative ankyrin repeat protein FPV223">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <sequence length="141" mass="16075" checksum="D29ED1CFD067C12E" modified="2000-10-01" version="1">MNVLKLLCKYHVDINISSHSSGRTSLHYAVLFNHKRALSFLLARGADVFKKDACMCTPLYYAMLSDQRDMVTMLLHSKKYIVKFRNKLDLHNAIETGNIKVIKTLLDNGVNENSVDKDGLTPLHYAVKYGNISIVKMFVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J520</accession>
    <name>Q9J520_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein FPV215</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV215</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039178.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486787"/>
    <dbReference type="KEGG" id="vg:1486787"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="74" mass="7859" checksum="3AA2D60BC978012A" modified="2000-10-01" version="1">MQFFTPILMLVTSLAIITAVTMISLLITATIILPISLILPSTSSSTFLVTVISLISSVSIVAIAINTVMIIRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J521</accession>
    <name>Q9J521_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV214 Putative 13.7 kDa protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV214</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039177.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486786"/>
    <dbReference type="KEGG" id="vg:1486786"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="124" mass="13933" checksum="90C4095D04C01EEA" modified="2000-10-01" version="1">MLYIYIISTSILLVKGYVIENNNCGCGNITASKDVTTSNSTFDRLLCTVYMSSEDGYIYWIGPNSTFIENLEGANEGSDNTFEVGNECYKHTRELNITSRDYVGKNFTCTSMTEYGTTFFNVIL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J535</accession>
    <name>V198_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative C-type lectin protein FPV198</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV198</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039161.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J535"/>
    <dbReference type="GeneID" id="1486770"/>
    <dbReference type="KEGG" id="vg:1486770"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0430">Lectin</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000046727" description="Putative C-type lectin protein FPV198">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin">
        <location>
            <begin position="50"/>
            <end position="169"/>
        </location>
    </feature>
    <sequence length="173" mass="19732" checksum="8260A4EE120F74E5" modified="2000-10-01" version="1">MNRQSSEKLKKTCAWFIHLIASMCGTGLLGLFVTNVTLYRQIKICGNREGMSGWVQINNNCYTMVENITFDELIGHCTKHDSIIPNALDQSEVLIVSSVLGVKDHWMPFTKKSRNWFHGKLPVNIKGDGDKREELGKPRKPDKSEKCTIYYDNGIIEENCNKKHTGICFSPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J542</accession>
    <name>Q9J542_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF FPV191 A type inclusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV191</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039154.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486763"/>
    <dbReference type="KEGG" id="vg:1486763"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019031">
        <property type="term" value="C:viral envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019064">
        <property type="term" value="P:fusion of virus membrane with host plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003436">
        <property type="entry name" value="Chordopox_Fusion/A27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009285">
        <property type="entry name" value="Orthopox_A30L/A26L"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06086">
        <property type="entry name" value="Pox_A30L_A26L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02346">
        <property type="entry name" value="Vac_Fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01847">
        <property type="entry name" value="VIRALFUSION"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="474" mass="55037" checksum="43A908D1E2220FE6" modified="2000-10-01" version="1">MDVVPGAGEEEDDVVIPKPVSTNDPVTLFVSIVKESWNTQLRQDTYINYYYANCIRNIIRYHMESFKDHISVSEFYGKILNYETLIKGRAYTSLMSYNHGEFAEMLQQIHSFNSVDTVGKYIAFIVMFFITTAKERISLTQDETDKIYETIRRIRHRYFNRIASIHMRFRCKSMFIGIPCYLFPDDSAFGEILEWGSNMFSRPYMIMHKKYIEYLKNNVRNPGNRKVVMLATTASTWYFNNSVPEYVLKGLCYRHDDLIATETNDKVRFYLRFLPDSKKYVYHEVNTRTPQVKFPSPVSVKFDTFAISIGNPEEEGNRPDDLITTYEHPFYTIGEVKSAGGVKLDSDDLVPPEDGKASDGLLIDEDPIDDDDDDDDDDDDDRIDKNIPENGKVDIYDENKKRGDLGSLKQKALRRLERRLGRIEQDHVEVAKSCSIVAEAIDRLERHADTLRHSMVNLAKKIDYQTGYGHLYME</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2021-06-02" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J549</accession>
    <name>A19_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein A19 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV184</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae A19 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039147.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486756"/>
    <dbReference type="KEGG" id="vg:1486756"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007769">
        <property type="entry name" value="Poxvirus_A19"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05077">
        <property type="entry name" value="DUF678"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000099265" description="Protein A19 homolog">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="88" mass="9585" checksum="F82C8687B08EFCEA" modified="2000-10-01" version="1">MADSTAGAKKRKKRSTSATSTRKEPPTVIPEDECTTCSICQSKLVMFSGVSKYKLSDYLNTGKVFTNSNIRCKACGSSLCHLRDLSKS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J552</accession>
    <name>A16_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Virion membrane protein A16 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV181</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry. Also plays a role in cell-cell fusion (syncytium formation).</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of a stable entry-fusion complex (EFC) which is at least composed of proteins A16, A21, A28, G3, G9, H2, J5, and L5. Formation of the viral membrane is necessary for the assembly of the complex. Interacts with G9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Virion membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <text evidence="1">Component of the mature virion (MV) membrane. The mature virion is located in the cytoplasm of infected cells and is probably released by cell lysis.</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Most cysteines are linked by disulfide bonds. They are created by the viral disulfide bond formation pathway, a poxvirus-specific redox pathway that operates on the cytoplasmic side of the MV membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the poxviridae A16/G9/J5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039144.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486753"/>
    <dbReference type="KEGG" id="vg:1486753"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019031">
        <property type="term" value="C:viral envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055036">
        <property type="term" value="C:virion membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039663">
        <property type="term" value="P:membrane fusion involved in viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046718">
        <property type="term" value="P:viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004251">
        <property type="entry name" value="Pox_virus_G9/A16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03003">
        <property type="entry name" value="Pox_G9-A16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-1168">Fusion of virus membrane with host membrane</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0446">Lipid-binding</keyword>
    <keyword id="KW-0449">Lipoprotein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0519">Myristate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0735">Signal-anchor</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0261">Viral envelope protein</keyword>
    <keyword id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <keyword id="KW-1160">Virus entry into host cell</keyword>
    <feature type="initiator methionine" description="Removed; by host" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000099256" description="Virion membrane protein A16 homolog">
        <location>
            <begin position="2"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="topological domain" description="Virion surface" evidence="2">
        <location>
            <begin position="2"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="topological domain" description="Intravirion" evidence="2">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="N-myristoyl glycine; by host" evidence="1">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="369" mass="42082" checksum="380A71032C18BB99" modified="2000-10-01" version="1">MGQHVSNITVIATPQAPETKYLRVEYTGGYDDEYIRFFEAENIHSGDIGSEISPPFCLTRDTTVKQCASFLSPEAKKKFVIVPGEPCKSLSFRPGSILDLQKIPYGTESYVLDGTRCRFINIDYLYTDPDIKRCCNKESDKDCPEIFSNNYETDHCDTIMSSICLQTPGSLPCREWLEKKREVAFDTYMKVCSDHLDANYCSDFVDYTRPDNFGYSDAAILSYCSKHRNNPNCWCVTTPKNDKLFSLELALGPKVCWLHECTDKSKDRKYLLFDQDVQRTNCKYIGCNINVDTLRLRNSVAELIAKCGGSIAEDTVLGDDSYNKEAKLPSFFSIIPVCIVLLCLFVLFYFLRIYDAKVINSNTINVYRK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J560</accession>
    <name>A9_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Protein A9 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV173</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Envelope protein. Required for an early step in virion morphogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Host cytoplasm</location>
        </subcellularLocation>
        <text evidence="1">Component of the mature virion (MV) membrane. The mature virion is located in the cytoplasm of infected cells and is probably released by cell lysis. Also found in cytoplasmic virus factories (By similarity).</text>
    </comment>
    <comment type="induction">
        <text>Expressed in the late phase of the viral replicative cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the chordopoxvirinae A9 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039136.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J560"/>
    <dbReference type="GeneID" id="1486721"/>
    <dbReference type="KEGG" id="vg:1486721"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006920">
        <property type="entry name" value="Poxvirus_A9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04835">
        <property type="entry name" value="Pox_A9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0325">Glycoprotein</keyword>
    <keyword id="KW-1035">Host cytoplasm</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0732">Signal</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0261">Viral envelope protein</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000099229" description="Protein A9 homolog">
        <location>
            <begin position="22"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="topological domain" description="Intravirion" evidence="2">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="topological domain" description="Virion surface" evidence="2">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine; by host" evidence="2">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="76" mass="8594" checksum="D7825336FF026759" modified="2000-10-01" version="1" precursor="true">MSCYSSILNSISTLAFLQVASNVIELVRHCIMHFCETRIRCNTLAFVILKILITMVIYFMIGLGLFYLAKNGTEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-05-25" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J561</accession>
    <name>Q9J561_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Intermediate transcription factor 3 small subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">VITF-3 32 kDa subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">VITF-3 small subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FPV172</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">NVSL</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts with RNA polymerase to initiate transcription from intermediate gene promoters.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer of a 45 kDa (A23R) and a 32 kDa (A8R) subunit to form the virus intermediate transcription factor (VITF)-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chordopoxvirinae A8 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039135.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486720"/>
    <dbReference type="KEGG" id="vg:1486720"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006834">
        <property type="entry name" value="Pox_A8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04745">
        <property type="entry name" value="Pox_A8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AAF44516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="301" mass="35661" checksum="41A9731209DC2172" modified="2000-10-01" version="1">MYEIVPDLDTSMSLELGDFKLSTTRTKPREEDNQYYLSKNRRMYVCSSKGSERAKSLGFFLSKIPFLNYKEKNYMFQKMDNINNIQLTKKNNVISAPYVILINLSANGFKFTESFLEIYFPEIYKESSKKFKFNTQIQLIQEKLGYEHSSYYNIEFEHYYTTVCLILQSKRNMEKEDPELFDIREMSPILKSLSEITYKLYVLYIKSKFVQWSISSSAVVTQLVNTVLITVYNLVTKFITENKTFKCKLAHNNELPIDMLVSYYEEFSEIITNLMKLNRYRINKHIQETLLSFCTIFGEVE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2020-12-02" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J566</accession>
    <name>VLTF3_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Viral late gene transcription factor 3</fullName>
            <shortName>VLTF-3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">VLTF3</name>
        <name type="ordered locus">FPV165</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text>Acts with RNA polymerase to initiate transcription from late gene promoters.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with the late transcription elongation factor H5/VLTF-4. Interacts with the late transcription factors VLTF-1.</text>
    </comment>
    <comment type="developmental stage">
        <text>Intermediate stages of infection.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleo-cytoplasmic large DNA viruses (NCLDVs) VLTF-3 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039128.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="PRIDE" id="Q9J566"/>
    <dbReference type="GeneID" id="1486713"/>
    <dbReference type="KEGG" id="vg:1486713"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007031">
        <property type="entry name" value="Poxvirus_VLTF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014900">
        <property type="entry name" value="VLTF-3_Zn_ribbon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08792">
        <property type="entry name" value="A2L_zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04947">
        <property type="entry name" value="Pox_VLTF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0010">Activator</keyword>
    <keyword id="KW-0426">Late protein</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="chain" id="PRO_0000099179" description="Viral late gene transcription factor 3">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="zinc finger region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="225" mass="26226" checksum="B45D4B50C8F4E18E" modified="2000-10-01" version="1">MSNLKHCSNCKHNGLITESNHEFCIFCQSIFQLSNKVSKKSNFHVSNKLIHLRNVLRRLLSNQCSSDVIVELKSVMTKNNISSTDIDANFVSSFLKANEKINKKDYKLVFEIINHIKEEKLNLDTSKINEVIEIFKHLVFFCQENTPSKTINYSFFLDKIFSLTSVTNNLKPQTVKNYTKNNSNQLVWENFLDYMKKKKINTSVYDYGHEYVFVDYGFTTCSLEV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J569</accession>
    <name>V162_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV162</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV162</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039125.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J569"/>
    <dbReference type="GeneID" id="1486710"/>
    <dbReference type="KEGG" id="vg:1486710"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018272">
        <property type="entry name" value="PRANC_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09372">
        <property type="entry name" value="PRANC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067112" description="Putative ankyrin repeat protein FPV162">
        <location>
            <begin position="1"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="124"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="159"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 6">
        <location>
            <begin position="193"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 7">
        <location>
            <begin position="227"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 8">
        <location>
            <begin position="261"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 9">
        <location>
            <begin position="295"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 10">
        <location>
            <begin position="329"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 11">
        <location>
            <begin position="366"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 12">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 13">
        <location>
            <begin position="432"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 14">
        <location>
            <begin position="504"/>
            <end position="533"/>
        </location>
    </feature>
    <sequence length="603" mass="66543" checksum="8FFE3E464DB9D16D" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J574</accession>
    <name>Q9J574_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV156 HT motif gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV156</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039119.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486704"/>
    <dbReference type="KEGG" id="vg:1486704"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045408">
        <property type="entry name" value="DUF5890"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19240">
        <property type="entry name" value="DUF5890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="132" mass="16085" checksum="9250A54DAA744715" modified="2000-10-01" version="1">MCFKDVRTLYKNKRRNNCEIVYKCNSYAENDNIFWYEKSKGDIVCIDMRSSDEIFDAFLMYHIATRYAYHDDDIYLQIVLYYSNNQNVISYITKNKYVKYIRNKTRDDIHKVKILALEDFTTEEIYCWISNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J576</accession>
    <name>Q9J576_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV154</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV154</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039117.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486702"/>
    <dbReference type="KEGG" id="vg:1486702"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="150" mass="17948" checksum="71A2629E46D0B554" modified="2000-10-01" version="1">MSGNKNIIFSEILEILNSKYKKDMKLLNIVYEKYRAIIFWELDDIKSESKKLRTQYQEELSKNLMSDLLKNKYQRDIRYFRSKLIELKTRLDDIERKLIDRSNSLMLKYVSDLQKIQSYLSSKTSDSVIIDLVTQLIAYRIVDGYKEAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J578</accession>
    <name>Q9J578_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV152 HT motif gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV152</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039115.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486700"/>
    <dbReference type="KEGG" id="vg:1486700"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045408">
        <property type="entry name" value="DUF5890"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19240">
        <property type="entry name" value="DUF5890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="127" mass="15113" checksum="47C6FE1337C3D6AA" modified="2000-10-01" version="1">MENGNCKSLILTVHDNDVNTVSYDEQFFWKEFAVGDLISLQISNTCDIPRIFECYHVITDDKYRNQDQHFQIGLYSKNKKYEYTYYTTESEYAELVNNASLCDLYKISIMPIRELTNKEIEDKFYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-10-07" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J581</accession>
    <name>Q9J581_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein FPV149</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV149</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039112.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486697"/>
    <dbReference type="KEGG" id="vg:1486697"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001496">
        <property type="entry name" value="SOCS_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036036">
        <property type="entry name" value="SOCS_box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037139">
        <property type="entry name" value="VHL_alpha_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158235">
        <property type="entry name" value="SSF158235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50225">
        <property type="entry name" value="SOCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SOCS box" evidence="1">
        <location>
            <begin position="151"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="186" mass="21615" checksum="0F323E7AC81CF00B" modified="2000-10-01" version="1">MNICINPESTNCVHSTNDVKARTPIKNKYLPDYALIRFMIKKFNKLFIEKGLPITAVYSWTVFREAAICRGQYRSWIMSFIHTISGNNIANFRLDRAYSDSRYNSIIIDSTSGKIICEGIGIMEKLRLHGVDFINDKLFTEEEIITHVYGVQPLQDICIRMIRNTVSRDDYDKLELPRSLLKEIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-05-25" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J591</accession>
    <name>Q9J591_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ORF FPV139</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FPV139</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">NVSL</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Part of a stable entry-fusion complex (EFC) which is at least composed of proteins A16, A21, A28, G3, G9, H2, J5, and L5. Formation of the viral membrane is necessary for the assembly of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type III membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Virion membrane</location>
            <topology evidence="2">Single-pass type III membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039102.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486687"/>
    <dbReference type="KEGG" id="vg:1486687"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055036">
        <property type="term" value="C:virion membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039663">
        <property type="term" value="P:membrane fusion involved in viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046718">
        <property type="term" value="P:viral entry into host cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005023">
        <property type="entry name" value="Pox_LP_H2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03356">
        <property type="entry name" value="Pox_LP_H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1168">Fusion of virus membrane with host membrane</keyword>
    <keyword evidence="5" id="KW-0426">Late protein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-1162">Viral penetration into host cytoplasm</keyword>
    <keyword evidence="3" id="KW-1160">Virus entry into host cell</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AAF44483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="190" mass="21959" checksum="33150A5B266530FA" modified="2000-10-01" version="1">MGNEVELSVHGIELNYARNNITKNIRYARVSTLIFFFLLLVISVVLFFFQISNNSIFSTLSKYTRIKNNLSSWKPLVIQKSKINSELGKHAALNRQDLMRFKCVDFGSYFLPVRLNNNNFLPEAVRRGDGDGWMIKKAGKYDPAAEQYCDFILDRYKDTITCGDQMFNSLGYSGYFESGHWCQTFLDLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5A9</accession>
    <name>Q9J5A9_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV113</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV113</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039076.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486661"/>
    <dbReference type="KEGG" id="vg:1486661"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="66" mass="7566" checksum="F32628307E1C3FF1" modified="2000-10-01" version="1">MADRNVKSSNNLTKKRIKKVRIKQPDPTTEEIDTYGADINVKLIQPNISIEQDDGEIQTIHIDDFN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5B7</accession>
    <name>F17_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Phosphoprotein F17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV103</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an essential role in virion assembly and morphogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Self-associates to form high molecular-weight forms.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
        <text evidence="1">Major component of the virion comprising about 10% of the virion mass.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Phosphorylated on two serines.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the poxviridae F17 protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039066.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486651"/>
    <dbReference type="KEGG" id="vg:1486651"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006854">
        <property type="entry name" value="Phosphoprotein_F17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04767">
        <property type="entry name" value="Pox_F17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003688">
        <property type="entry name" value="VAC_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0597">Phosphoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0946">Virion</keyword>
    <feature type="chain" id="PRO_0000099523" description="Phosphoprotein F17">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="1">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="P07396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="114" mass="12742" checksum="FEC99BAC5487B8EE" modified="2000-10-01" version="1">MEESAGTPFHDPKYFVSPFILNTDEGRYLVLKAIKLCNVRTIDCMKQETSCVLKVDKPQSPCPISSSDSAPKCYMQQTSPQQQRQAPQLRFINTGALSNLFANTTDKAARVINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-08-03" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5C1</accession>
    <name>Q9J5C1_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ORF FPV099 variola B22R gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">FPV099</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039062.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486647"/>
    <dbReference type="KEGG" id="vg:1486647"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007490">
        <property type="entry name" value="Poxvirus_B22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025128">
        <property type="entry name" value="Poxvirus_B22R_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025133">
        <property type="entry name" value="Poxvirus_B22R_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04395">
        <property type="entry name" value="Poxvirus_B22R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13168">
        <property type="entry name" value="Poxvirus_B22R_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13169">
        <property type="entry name" value="Poxvirus_B22R_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1893"/>
            <end position="1919"/>
        </location>
    </feature>
    <feature type="domain" description="Poxvirus_B22R_N" evidence="4">
        <location>
            <begin position="32"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Poxvirus_B22R_C" evidence="3">
        <location>
            <begin position="946"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="880"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="735"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="770"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AAF44443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="1949" mass="219449" checksum="B974590AE8543025" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5D3</accession>
    <name>Q9J5D3_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV079 Putative elongation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV079</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039041.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486627"/>
    <dbReference type="KEGG" id="vg:1486627"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008446">
        <property type="entry name" value="Chordopox_G2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05796">
        <property type="entry name" value="Chordopox_G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="225" mass="26027" checksum="A117C796CE51E3E4" modified="2000-10-01" version="1">MSFRTLISYNLLKYLDSGDEAYMEKFISLCNSFNVDRVKVLTKYYNSKNTKLISKALNCDTYLKEIELSYPDNILKELVTIKLGKFTKTIKRSYKLPNEGIGIIVINGNEIKYNADNNTIAYSKLKYIPSIYRYTEYPDGIKTEDIPKESIVLIFGKDYLDYFTYMLAKKVLSNKDIKIKVTDQCIDHLLNESNTDMLDTVFSNKPNNIISSTLNDIYLSLRSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5D7</accession>
    <name>Q9J5D7_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein FPV074</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FPV074</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039037.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486622"/>
    <dbReference type="KEGG" id="vg:1486622"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAF44418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="104" mass="12185" checksum="D4708A0DA7FC5969" modified="2000-10-01" version="1">MIDTSIYLAILSSFIAVIMNNISLPLTAIFIITMYVIHIRLAINIMFLYILSWIIDINILIIIFLGIIFMRKTGKYLNNYIRSRKSSRKITRYTVLLLDKEKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5D9</accession>
    <name>Q9J5D9_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ORF FPV072 beta-Nerve growth factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FPV072</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039035.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486620"/>
    <dbReference type="KEGG" id="vg:1486620"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020408">
        <property type="entry name" value="Nerve_growth_factor-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002072">
        <property type="entry name" value="Nerve_growth_factor-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019846">
        <property type="entry name" value="Nerve_growth_factor_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11589">
        <property type="entry name" value="PTHR11589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00243">
        <property type="entry name" value="NGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00268">
        <property type="entry name" value="NGF"/>
    </dbReference>
    <dbReference type="SMART" id="SM00140">
        <property type="entry name" value="NGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="SSF57501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00248">
        <property type="entry name" value="NGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="NGF" evidence="2">
        <location>
            <begin position="71"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AAF44416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="186" mass="21121" checksum="D2A2125D90D2E759" modified="2000-10-01" version="1">MAYHTHPCNFRRLIFICVLGIVCKGSLLQFTNPYLINDKLDTSKVVFSTRTPNIEHRGKRSIDELLSVGNTSEGIYLSCESSSTWVANKTTVFDHRGNKLELLDQIVHNKQVYYQYLFETKCKEYPAISGCLGIDTRFWSSYCSTSHSFVNSIVIKNGMPSWEYIRIGTSCVCVVQLKCKANVALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5E4</accession>
    <name>Q9J5E4_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV067 HT motif gene family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV067</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039030.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486615"/>
    <dbReference type="KEGG" id="vg:1486615"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045408">
        <property type="entry name" value="DUF5890"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19240">
        <property type="entry name" value="DUF5890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="90" mass="10920" checksum="87FE71C4AB57BBD0" modified="2000-10-01" version="1">MFISPIMVKIVFVMNSRKDIDVILCRFHEMTNYAFKSVYQRFCYRLQCSRMGKYHKTVTFRNTIEPKIKELIKRIRGFTVYKITIQPEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5E7</accession>
    <name>Q9J5E7_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ORF FPV064 Glutathione peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FPV064</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">NVSL</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039027.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486612"/>
    <dbReference type="KEGG" id="vg:1486612"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="PTHR11592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000303">
        <property type="entry name" value="Glutathion_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AAF44408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="200" mass="23520" checksum="63E0414CF2179AED" modified="2000-10-01" version="1">MNDDWILHHTIYNFNLNLLNGESFDFKTYKDKICIFVNVASEXRLADRNYKELTKLYDRYFCDGLRIMAFPCNQFGGQEPGGVKEIMETIKKYSVLFDVSEKVIVNTIYAHPLWKWLQTRPILGDVPGPIKWNFCKFLISPFGYVIKRFDPEVNPMSIQKDIEHVIEQRANEEMTINRWVMPDTHCSEEESLSKDVLNDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5F6</accession>
    <name>Q9J5F6_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ORF FPV047 Semaphorin vaccinia A39R homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">FPV047</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">NVSL</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039010.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486595"/>
    <dbReference type="KEGG" id="vg:1486595"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030215">
        <property type="term" value="F:semaphorin receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002165">
        <property type="entry name" value="Plexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016201">
        <property type="entry name" value="PSI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001627">
        <property type="entry name" value="Semap_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036352">
        <property type="entry name" value="Semap_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027231">
        <property type="entry name" value="Semaphorin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11036">
        <property type="entry name" value="PTHR11036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01437">
        <property type="entry name" value="PSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01403">
        <property type="entry name" value="Sema"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00423">
        <property type="entry name" value="PSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00630">
        <property type="entry name" value="Sema"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101912">
        <property type="entry name" value="SSF101912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51004">
        <property type="entry name" value="SEMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sema" evidence="5">
        <location>
            <begin position="27"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="489"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="AAF44391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="612" mass="69515" checksum="175D0D18EC274E23" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5F9</accession>
    <accession>Q67478</accession>
    <accession>Q67479</accession>
    <name>V044_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized serpin-like protein FPV044</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV044</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1994" name="J. Gen. Virol." volume="75" first="2495" last="2498">
            <title>Deletion of fowlpox virus homologues of vaccinia virus genes between the 3 beta-hydroxysteroid dehydrogenase (A44L) and DNA ligase (A50R) genes.</title>
            <authorList>
                <person name="Skinner M.A."/>
                <person name="Moore J.B."/>
                <person name="Binns M.M."/>
                <person name="Smith G.L."/>
                <person name="Boursnell M.E.G."/>
            </authorList>
            <dbReference type="PubMed" id="8077953"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the serpin family. Poxviruses subfamily.</text>
    </comment>
    <comment type="sequence caution" evidence="1">
        <conflict type="frameshift">
            <sequence resource="EMBL-CDS" id="CAA82803" version="1"/>
        </conflict>
    </comment>
    <comment type="sequence caution" evidence="1">
        <conflict type="frameshift">
            <sequence resource="EMBL-CDS" id="CAA82804" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="Z29716">
        <property type="protein sequence ID" value="CAA82803.1"/>
        <property type="status" value="ALT_FRAME"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="Z29716">
        <property type="protein sequence ID" value="CAA82804.1"/>
        <property type="status" value="ALT_FRAME"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S41972">
        <property type="entry name" value="S41972"/>
    </dbReference>
    <dbReference type="PIR" id="S41973">
        <property type="entry name" value="S41973"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039007.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5F9"/>
    <dbReference type="PRIDE" id="Q9J5F9"/>
    <dbReference type="GeneID" id="1486592"/>
    <dbReference type="KEGG" id="vg:1486592"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023795">
        <property type="entry name" value="Serpin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="PTHR11461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="SSF56574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00284">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0646">Protease inhibitor</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="chain" id="PRO_0000094156" description="Uncharacterized serpin-like protein FPV044">
        <location>
            <begin position="1"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="358" mass="41441" checksum="79A3F5174ED05998" modified="2000-10-01" version="1">MSNVSSINNKLAFISTKFYELITKRIPDKNIVISPPSIMLIVKMLLKASTDRSRNQLLDLLYMLPLDDDEDDDSNTDKILKELLSRTEYTSIFFIDHNKRIHDSYKKYVSKSNITSLVSGDVTVLCNKMSELNYNTEDMLSSIRKPPEASILFNIKYSDLWESPFSDNDSHKFFVTKYLTKVVPYIITSGMFGHMYCHEIKSNIINIPYLHNTYSMLLFFADTYKNFKYLEKHITPRILLSSKIGVSNMKYSEISVSIPKFSIQTQHNIKSVFVELGITDIFDENCSMKSVSPDKFSITSLFVKSQVDFINNKIVLGDQKKWEKISNNNYHINRPFIFVIKYNKTGSVVFMGKIKDPE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5G4</accession>
    <name>ARBH_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Apoptosis regulator Bcl-2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV039</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2007" name="J. Virol." volume="81" first="11032" last="11045">
            <title>Fowlpox virus encodes a Bcl-2 homologue that protects cells from apoptotic death through interaction with the proapoptotic protein Bak.</title>
            <authorList>
                <person name="Banadyga L."/>
                <person name="Gerig J."/>
                <person name="Stewart T."/>
                <person name="Barry M."/>
            </authorList>
            <dbReference type="PubMed" id="17686864"/>
            <dbReference type="DOI" id="10.1128/JVI.00734-07"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>INTERACTION WITH HOST BAK1</scope>
        <scope>SUBCELLULAR LOCATION</scope>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2009" name="J. Virol." volume="83" first="7085" last="7098">
            <title>The fowlpox virus BCL-2 homologue, FPV039, interacts with activated Bax and a discrete subset of BH3-only proteins to inhibit apoptosis.</title>
            <authorList>
                <person name="Banadyga L."/>
                <person name="Veugelers K."/>
                <person name="Campbell S."/>
                <person name="Barry M."/>
            </authorList>
            <dbReference type="PubMed" id="19439472"/>
            <dbReference type="DOI" id="10.1128/JVI.00437-09"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>INTERACTION WITH HOST BAX</scope>
    </reference>
    <reference key="4">
        <citation type="journal article" date="2017" name="J. Biol. Chem." volume="292" first="9010" last="9021">
            <title>Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039.</title>
            <authorList>
                <person name="Anasir M.I."/>
                <person name="Caria S."/>
                <person name="Skinner M.A."/>
                <person name="Kvansakul M."/>
            </authorList>
            <dbReference type="PubMed" id="28411240"/>
            <dbReference type="DOI" id="10.1074/jbc.M116.768879"/>
        </citation>
        <scope>X-RAY CRYSTALLOGRAPHY (1.35 ANGSTROMS) OF 1-143</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Plays a role in the inhibition of host apoptosis by sequestering and inactivating multiple proapoptotic BCL-2 proteins, including BAK1 and BAX.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 2">Interacts with host BAX; this interaction inhibits BAX oligomerization and subsequent activation. Interacts with host BAK1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Bcl-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039002.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="PDB" id="5TZP">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="1.35 A"/>
        <property type="chains" value="A=1-143"/>
    </dbReference>
    <dbReference type="PDB" id="5TZQ">
        <property type="method" value="X-ray"/>
        <property type="resolution" value="1.65 A"/>
        <property type="chains" value="A/B=1-143"/>
    </dbReference>
    <dbReference type="PDBsum" id="5TZP"/>
    <dbReference type="PDBsum" id="5TZQ"/>
    <dbReference type="SASBDB" id="Q9J5G4"/>
    <dbReference type="SMR" id="Q9J5G4"/>
    <dbReference type="GeneID" id="1486587"/>
    <dbReference type="KEGG" id="vg:1486587"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033650">
        <property type="term" value="C:host cell mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019050">
        <property type="term" value="P:suppression by virus of host apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.437.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036834">
        <property type="entry name" value="Bcl-2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046371">
        <property type="entry name" value="Bcl-2_BH1-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002475">
        <property type="entry name" value="Bcl2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020717">
        <property type="entry name" value="Bcl2_BH1_motif_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00452">
        <property type="entry name" value="Bcl-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56854">
        <property type="entry name" value="SSF56854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50062">
        <property type="entry name" value="BCL2_FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01080">
        <property type="entry name" value="BH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0002">3D-structure</keyword>
    <keyword id="KW-0053">Apoptosis</keyword>
    <keyword id="KW-1045">Host mitochondrion</keyword>
    <keyword id="KW-0945">Host-virus interaction</keyword>
    <keyword id="KW-1081">Inhibition of host apoptosis by viral BCL2-like protein</keyword>
    <keyword id="KW-1119">Modulation of host cell apoptosis by virus</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000143093" description="Apoptosis regulator Bcl-2 homolog">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="BH1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="BH2">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="helix" evidence="4">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="helix" evidence="4">
        <location>
            <begin position="32"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="helix" evidence="4">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="helix" evidence="4">
        <location>
            <begin position="69"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="helix" evidence="4">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="strand" evidence="4">
        <location>
            <begin position="103"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="helix" evidence="4">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="helix" evidence="4">
        <location>
            <begin position="134"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000269" key="1">
        <source>
            <dbReference type="PubMed" id="17686864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="19439472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <evidence type="ECO:0007829" key="4">
        <source>
            <dbReference type="PDB" id="5TZP"/>
        </source>
    </evidence>
    <sequence length="175" mass="20458" checksum="4537425136506629" modified="2000-10-01" version="1">MASSNMKDETYYIALNMIQNYIIEYNTNKPRKSFVIDSISYDVLKAACKSVIKTNYNEFDIIISRNIDFNVIVTQVLEDKINWGRIITIIAFCAYYSKKVKQDTSPQYYDGIISEAITDAILSKYRSWFIDQDYWNGIRIYKNYSYIFNTASYCIFTASLIIASLAVFKICSFYM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5G5</accession>
    <name>DUT_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName>dUTPase</shortName>
            <ecNumber>3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">DUT</name>
        <name type="ordered locus">FPV038</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction>
            <text>dUTP + H2O = diphosphate + dUMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dUTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23"/>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_039001.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5G5"/>
    <dbReference type="GeneID" id="1486586"/>
    <dbReference type="KEGG" id="vg:1486586"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="PTHR11241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0546">Nucleotide metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000182947" description="Deoxyuridine 5'-triphosphate nucleotidohydrolase">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="145" mass="16253" checksum="94CF5F6963B47D08" modified="2000-10-01" version="1">MEEVTVYKISDRAKLPYKQTSYSAGYDLYSAYDYVIEPMNKELIKTDIILKIPNGYYGRIAPRSGLAYNYFIDVGAGVIDSDYRGNVGVLLFNFGSTQFNVCKGDRIAQIIFEKIAYPKIIEVTTLEEINITDRGNSGFGSTGLK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5G9</accession>
    <accession>O90757</accession>
    <name>V034_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV034</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">ANK2</name>
        <name type="ordered locus">FPV034</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="1998" name="J. Virol." volume="72" first="6742" last="6751">
            <title>Fowlpox virus encodes nonessential homologs of cellular alpha-SNAP, PC-1, and an orphan human homolog of a secreted nematode protein.</title>
            <authorList>
                <person name="Laidlaw S.M."/>
                <person name="Anwar M.A."/>
                <person name="Thomas W."/>
                <person name="Green P."/>
                <person name="Shaw K."/>
                <person name="Skinner M.A."/>
            </authorList>
            <dbReference type="PubMed" id="9658122"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <source>
            <strain>FP-9 / Isolate HP-438</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AJ006408">
        <property type="protein sequence ID" value="CAA07010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038997.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5G9"/>
    <dbReference type="GeneID" id="1486582"/>
    <dbReference type="KEGG" id="vg:1486582"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
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            <end position="449"/>
        </location>
    </feature>
    <sequence length="578" mass="65788" checksum="D47F02B98BABF693" modified="2000-10-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5I1</accession>
    <name>Q9J5I1_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ORF FPV020 C4L/C10L-like gene family protein (Vaccinia C10L)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV020</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038983.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486739"/>
    <dbReference type="KEGG" id="vg:1486739"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005004">
        <property type="entry name" value="Poxvirus_C4/C10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03336">
        <property type="entry name" value="Pox_C4_C10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003698">
        <property type="entry name" value="VAC_C10L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="426" mass="49587" checksum="1B749B0352498BE4" modified="2000-10-01" version="1">MSFTYIRDGIPKMHIFSDDYFSDFKKLLIEEIETNYMDYDFSESRILDEHTGYEILDLEHCKSKQIVYESLCKDLTTKLENLIVSQLKYIVSEVRVENKVTFVVYGVGDYLKKTNNKPCKKKSKNTLCMYILLLLQKATEGGKTKFYLKGINSLDISSDVLFDKSVYHETTIVESGVTYVALLDVTMKLKTEKGIVDTIEYLDVSINLYDRENNNTLCYCEVIYIAPPCNKKLVRAGILINRKGKCLLTHINNKIHSIEHPIVFSSFQDVSVSKFNREYTVAYLEKNTINDIAWSSIDSNENDNYLPNDKELFDKLMKISSKEHAKCYEIEYIDESNEDAEPYYAYCMVSKYYFKLPDKESIINYIIKQGDSLEAISTDWKELEDSKKRDLLSSYERDQLFKIVLSKQEYDLQSDESDSDITIDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2000-10-01" modified="2020-08-12" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5I6</accession>
    <name>Q9J5I6_FOWPN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein FPV015</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">FPV015</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">NVSL</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038978.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1486734"/>
    <dbReference type="KEGG" id="vg:1486734"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="AAF44359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000008597"/>
        </source>
    </evidence>
    <sequence length="177" mass="20657" checksum="38EF3294D1ADC97C" modified="2000-10-01" version="1">MVILREISSEIKSCFNEVTPITNSMVFMQVNGTRPTPESILKAFDYDTKCKFMTSCIIFNIFIGCLHPDTEYVSGCTQYTTRDEILNMVDGEGKFYVEKLSPMSEFCLAMAPLVYNEDLKSNMTDTNKCKNVNKEEMFKPTYDNYRDYRDYRSYEPENLVKCVNPNDVYETKKILLY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-02-23" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>Q9J5I7</accession>
    <name>V014_FOWPN</name>
    <protein>
        <recommendedName>
            <fullName>Putative ankyrin repeat protein FPV014</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">FPV014</name>
    </gene>
    <organism>
        <name type="scientific">Fowlpox virus (strain NVSL)</name>
        <name type="common">FPV</name>
        <dbReference type="NCBI Taxonomy" id="928301"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Varidnaviria</taxon>
            <taxon>Bamfordvirae</taxon>
            <taxon>Nucleocytoviricota</taxon>
            <taxon>Pokkesviricetes</taxon>
            <taxon>Chitovirales</taxon>
            <taxon>Poxviridae</taxon>
            <taxon>Chordopoxvirinae</taxon>
            <taxon>Avipoxvirus</taxon>
        </lineage>
    </organism>
    <organismHost>
        <name type="scientific">Vertebrata</name>
        <name type="common">vertebrates</name>
        <dbReference type="NCBI Taxonomy" id="7742"/>
    </organismHost>
    <reference key="1">
        <citation type="journal article" date="2000" name="J. Virol." volume="74" first="3815" last="3831">
            <title>The genome of fowlpox virus.</title>
            <authorList>
                <person name="Afonso C.L."/>
                <person name="Tulman E.R."/>
                <person name="Lu Z."/>
                <person name="Zsak L."/>
                <person name="Kutish G.F."/>
                <person name="Rock D.L."/>
            </authorList>
            <dbReference type="PubMed" id="10729156"/>
            <dbReference type="DOI" id="10.1128/JVI.74.8.3815-3831.2000"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <dbReference type="EMBL" id="AF198100">
        <property type="protein sequence ID" value="AAF44358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_038977.1">
        <property type="nucleotide sequence ID" value="NC_002188.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9J5I7"/>
    <dbReference type="GeneID" id="1486733"/>
    <dbReference type="KEGG" id="vg:1486733"/>
    <dbReference type="Proteomes" id="UP000008597">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018272">
        <property type="entry name" value="PRANC_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09372">
        <property type="entry name" value="PRANC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-0040">ANK repeat</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <feature type="chain" id="PRO_0000067103" description="Putative ankyrin repeat protein FPV014">
        <location>
            <begin position="1"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 1">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 2">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 3">
        <location>
            <begin position="99"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 4">
        <location>
            <begin position="131"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 5">
        <location>
            <begin position="164"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 6">
        <location>
            <begin position="197"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK 7">
        <location>
            <begin position="230"/>
            <end position="259"/>
        </location>
    </feature>
    <sequence length="437" mass="49081" checksum="BDAE820872F88346" modified="2000-10-01" version="1">MEVFEAIESGCVSDVIKALKGNDSDPNMVNEYGCSLLHCAVENGNTEIARILLLEGANPDLYTESTPTALHRAVILRHYDIVNLLMEFNVDPDNYENHESRTPLEYAVKLNDVKMTKTLLDYGADAEDIYRFNCPINDAAANGNLEICKLLIDAGARINSRSMGSVYTIHHAIRSGNYELVVELLSRGALPDVEDELSFSSLHHAVMEGSADMVLTLLEHGASVDVQDFCGRTPLFLAANASELDIVKVLLDFWADTSVSSGRNTPLSVCDLNSDTGIEIAKQIISTMVINTEYKYHKVINEEARRNDLEIIESNNEMKDWKDSCIEEVEKMRKTTLGSDRRSLLDLCLNCDDNAIAKCLNCISCEGFFIYRQLIEYTIERGLLRHESLDKALDVMEKAFEKNRNVKDNGLKDWSDLPLGIKYDILEKIDEEDLPYC</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>