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<entry dataset="TrEMBL" created="2014-09-03" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A060VT46</accession>
    <name>A0A060VT46_ONCMY</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ubiquitin-conjugating enzyme E2E 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GSONMT00077006001</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Oncorhynchus mykiss</name>
        <name type="common">Rainbow trout</name>
        <name type="synonym">Salmo gairdneri</name>
        <dbReference type="NCBI Taxonomy" id="8022"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Chordata</taxon>
            <taxon>Craniata</taxon>
            <taxon>Vertebrata</taxon>
            <taxon>Euteleostomi</taxon>
            <taxon>Actinopterygii</taxon>
            <taxon>Neopterygii</taxon>
            <taxon>Teleostei</taxon>
            <taxon>Protacanthopterygii</taxon>
            <taxon>Salmoniformes</taxon>
            <taxon>Salmonidae</taxon>
            <taxon>Salmoninae</taxon>
            <taxon>Oncorhynchus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2014" name="Nat. Commun." volume="5" first="3657" last="3657">
            <title>The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates.</title>
            <authorList>
                <person name="Berthelot C."/>
                <person name="Brunet F."/>
                <person name="Chalopin D."/>
                <person name="Juanchich A."/>
                <person name="Bernard M."/>
                <person name="Noel B."/>
                <person name="Bento P."/>
                <person name="Da Silva C."/>
                <person name="Labadie K."/>
                <person name="Alberti A."/>
                <person name="Aury J.M."/>
                <person name="Louis A."/>
                <person name="Dehais P."/>
                <person name="Bardou P."/>
                <person name="Montfort J."/>
                <person name="Klopp C."/>
                <person name="Cabau C."/>
                <person name="Gaspin C."/>
                <person name="Thorgaard G.H."/>
                <person name="Boussaha M."/>
                <person name="Quillet E."/>
                <person name="Guyomard R."/>
                <person name="Galiana D."/>
                <person name="Bobe J."/>
                <person name="Volff J.N."/>
                <person name="Genet C."/>
                <person name="Wincker P."/>
                <person name="Jaillon O."/>
                <person name="Roest Crollius H."/>
                <person name="Guiguen Y."/>
            </authorList>
            <dbReference type="PubMed" id="24755649"/>
            <dbReference type="DOI" id="10.1038/ncomms4657"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2014-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Genoscope - CEA"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2021-09" db="UniProtKB">
            <authorList>
                <consortium name="Ensembl"/>
            </authorList>
        </citation>
        <scope>IDENTIFICATION</scope>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="FR904296">
        <property type="protein sequence ID" value="CDQ58027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="8022.A0A060VT46"/>
    <dbReference type="Ensembl" id="ENSOMYT00000006430.2">
        <property type="protein sequence ID" value="ENSOMYP00000005775.1"/>
        <property type="gene ID" value="ENSOMYG00000002946.2"/>
    </dbReference>
    <dbReference type="GeneTree" id="ENSGT00940000165358"/>
    <dbReference type="Proteomes" id="UP000193380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000694395">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00195">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBQ-conjugat_E2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="SSF54495"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="6">
        <location>
            <begin position="46"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDQ58027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Ensembl" id="ENSOMYP00000005775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000193380"/>
        </source>
    </evidence>
    <sequence length="192" mass="21102" checksum="962C15089972C399" modified="2014-09-03" version="1">MSDKDSCVSTSSSSSSSSNQNKPKDTPCKKRESKASMSKTSKLLSTSAKRIQKELADITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDIAFTPDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYTTNRAEHDRTAKQWTKRYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-09-03" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A060WKM1</accession>
    <name>A0A060WKM1_ONCMY</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongation factor 1-alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GSONMT00072635001</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Oncorhynchus mykiss</name>
        <name type="common">Rainbow trout</name>
        <name type="synonym">Salmo gairdneri</name>
        <dbReference type="NCBI Taxonomy" id="8022"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Chordata</taxon>
            <taxon>Craniata</taxon>
            <taxon>Vertebrata</taxon>
            <taxon>Euteleostomi</taxon>
            <taxon>Actinopterygii</taxon>
            <taxon>Neopterygii</taxon>
            <taxon>Teleostei</taxon>
            <taxon>Protacanthopterygii</taxon>
            <taxon>Salmoniformes</taxon>
            <taxon>Salmonidae</taxon>
            <taxon>Salmoninae</taxon>
            <taxon>Oncorhynchus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2014" name="Nat. Commun." volume="5" first="3657" last="3657">
            <title>The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates.</title>
            <authorList>
                <person name="Berthelot C."/>
                <person name="Brunet F."/>
                <person name="Chalopin D."/>
                <person name="Juanchich A."/>
                <person name="Bernard M."/>
                <person name="Noel B."/>
                <person name="Bento P."/>
                <person name="Da Silva C."/>
                <person name="Labadie K."/>
                <person name="Alberti A."/>
                <person name="Aury J.M."/>
                <person name="Louis A."/>
                <person name="Dehais P."/>
                <person name="Bardou P."/>
                <person name="Montfort J."/>
                <person name="Klopp C."/>
                <person name="Cabau C."/>
                <person name="Gaspin C."/>
                <person name="Thorgaard G.H."/>
                <person name="Boussaha M."/>
                <person name="Quillet E."/>
                <person name="Guyomard R."/>
                <person name="Galiana D."/>
                <person name="Bobe J."/>
                <person name="Volff J.N."/>
                <person name="Genet C."/>
                <person name="Wincker P."/>
                <person name="Jaillon O."/>
                <person name="Roest Crollius H."/>
                <person name="Guiguen Y."/>
            </authorList>
            <dbReference type="PubMed" id="24755649"/>
            <dbReference type="DOI" id="10.1038/ncomms4657"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2014-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Genoscope - CEA"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2021-09" db="UniProtKB">
            <authorList>
                <consortium name="Ensembl"/>
            </authorList>
        </citation>
        <scope>IDENTIFICATION</scope>
    </reference>
    <comment type="function">
        <text evidence="5">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FR904496">
        <property type="protein sequence ID" value="CDQ65135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="8022.A0A060WKM1"/>
    <dbReference type="Ensembl" id="ENSOMYT00000092619.2">
        <property type="protein sequence ID" value="ENSOMYP00000085027.1"/>
        <property type="gene ID" value="ENSOMYG00000039261.2"/>
    </dbReference>
    <dbReference type="GeneTree" id="ENSGT00940000162741"/>
    <dbReference type="OrthoDB" id="1150082at2759"/>
    <dbReference type="Proteomes" id="UP000193380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000694395">
        <property type="component" value="Chromosome 18"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_A">
        <property type="entry name" value="EF_Tu_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004539">
        <property type="entry name" value="Transl_elong_EF1A_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00483">
        <property type="entry name" value="EF-1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="5"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDQ65135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Ensembl" id="ENSOMYP00000085027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000193380"/>
        </source>
    </evidence>
    <sequence length="461" mass="50141" checksum="65826C27A4DBDE48" modified="2014-09-03" version="1">MGKEKIHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETGRYYVTIIDAPGHRDFIKNMITGTSQADCAVLVVAGGVGEFEAGISKNGQTREHALLAFTLGVKQLIVGVNKMDSTEPPYSQKRFEEIQKEVSTYIKKIGYNPATVAFVPISGWHGDNMLEASANMGWFKGWKVERKDGNANGVTLLEALDSILPPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGTLKAGMIVTFAPANVTTEVKSVEMHHETLESAMPGDNVGFNVKNVSVKDIRRGNVAGDSKNDPPMEAGTFTAQVIILNHPGQISQGYAPVLDCHTAHIACKFSELKEKIDRRSGKKLEDAPKFLKSGDAAIVDMIPGKPMCVESFQEYPPLGRFAVRDMRQTVAVGVIKAVDKKAASSGKVTKSAVKAGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-09-03" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A060WQG0</accession>
    <name>A0A060WQG0_ONCMY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GSONMT00046600001</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Oncorhynchus mykiss</name>
        <name type="common">Rainbow trout</name>
        <name type="synonym">Salmo gairdneri</name>
        <dbReference type="NCBI Taxonomy" id="8022"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Chordata</taxon>
            <taxon>Craniata</taxon>
            <taxon>Vertebrata</taxon>
            <taxon>Euteleostomi</taxon>
            <taxon>Actinopterygii</taxon>
            <taxon>Neopterygii</taxon>
            <taxon>Teleostei</taxon>
            <taxon>Protacanthopterygii</taxon>
            <taxon>Salmoniformes</taxon>
            <taxon>Salmonidae</taxon>
            <taxon>Salmoninae</taxon>
            <taxon>Oncorhynchus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2014" name="Nat. Commun." volume="5" first="3657" last="3657">
            <title>The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates.</title>
            <authorList>
                <person name="Berthelot C."/>
                <person name="Brunet F."/>
                <person name="Chalopin D."/>
                <person name="Juanchich A."/>
                <person name="Bernard M."/>
                <person name="Noel B."/>
                <person name="Bento P."/>
                <person name="Da Silva C."/>
                <person name="Labadie K."/>
                <person name="Alberti A."/>
                <person name="Aury J.M."/>
                <person name="Louis A."/>
                <person name="Dehais P."/>
                <person name="Bardou P."/>
                <person name="Montfort J."/>
                <person name="Klopp C."/>
                <person name="Cabau C."/>
                <person name="Gaspin C."/>
                <person name="Thorgaard G.H."/>
                <person name="Boussaha M."/>
                <person name="Quillet E."/>
                <person name="Guyomard R."/>
                <person name="Galiana D."/>
                <person name="Bobe J."/>
                <person name="Volff J.N."/>
                <person name="Genet C."/>
                <person name="Wincker P."/>
                <person name="Jaillon O."/>
                <person name="Roest Crollius H."/>
                <person name="Guiguen Y."/>
            </authorList>
            <dbReference type="PubMed" id="24755649"/>
            <dbReference type="DOI" id="10.1038/ncomms4657"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2014-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Genoscope - CEA"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2021-09" db="UniProtKB">
            <authorList>
                <consortium name="Ensembl"/>
            </authorList>
        </citation>
        <scope>IDENTIFICATION</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.2"/>
        </reaction>
    </comment>
    <dbReference type="EMBL" id="FR904658">
        <property type="protein sequence ID" value="CDQ69242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="8022.A0A060WQG0"/>
    <dbReference type="Ensembl" id="ENSOMYT00000096387.2">
        <property type="protein sequence ID" value="ENSOMYP00000088505.1"/>
        <property type="gene ID" value="ENSOMYG00000040879.2"/>
    </dbReference>
    <dbReference type="GeneTree" id="ENSGT00940000155871"/>
    <dbReference type="Proteomes" id="UP000193380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000694395">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="PTHR24070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDQ69242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Ensembl" id="ENSOMYP00000088505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000193380"/>
        </source>
    </evidence>
    <sequence length="188" mass="21453" checksum="DAC1B319BB259860" modified="2014-09-03" version="1">MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKEGKKKKKKSKTKCILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-09-03" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A060WYV9</accession>
    <accession>A0A8C7T643</accession>
    <name>A0A060WYV9_ONCMY</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Parvalbumin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GSONMT00063579001</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Oncorhynchus mykiss</name>
        <name type="common">Rainbow trout</name>
        <name type="synonym">Salmo gairdneri</name>
        <dbReference type="NCBI Taxonomy" id="8022"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Chordata</taxon>
            <taxon>Craniata</taxon>
            <taxon>Vertebrata</taxon>
            <taxon>Euteleostomi</taxon>
            <taxon>Actinopterygii</taxon>
            <taxon>Neopterygii</taxon>
            <taxon>Teleostei</taxon>
            <taxon>Protacanthopterygii</taxon>
            <taxon>Salmoniformes</taxon>
            <taxon>Salmonidae</taxon>
            <taxon>Salmoninae</taxon>
            <taxon>Oncorhynchus</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2014" name="Nat. Commun." volume="5" first="3657" last="3657">
            <title>The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates.</title>
            <authorList>
                <person name="Berthelot C."/>
                <person name="Brunet F."/>
                <person name="Chalopin D."/>
                <person name="Juanchich A."/>
                <person name="Bernard M."/>
                <person name="Noel B."/>
                <person name="Bento P."/>
                <person name="Da Silva C."/>
                <person name="Labadie K."/>
                <person name="Alberti A."/>
                <person name="Aury J.M."/>
                <person name="Louis A."/>
                <person name="Dehais P."/>
                <person name="Bardou P."/>
                <person name="Montfort J."/>
                <person name="Klopp C."/>
                <person name="Cabau C."/>
                <person name="Gaspin C."/>
                <person name="Thorgaard G.H."/>
                <person name="Boussaha M."/>
                <person name="Quillet E."/>
                <person name="Guyomard R."/>
                <person name="Galiana D."/>
                <person name="Bobe J."/>
                <person name="Volff J.N."/>
                <person name="Genet C."/>
                <person name="Wincker P."/>
                <person name="Jaillon O."/>
                <person name="Roest Crollius H."/>
                <person name="Guiguen Y."/>
            </authorList>
            <dbReference type="PubMed" id="24755649"/>
            <dbReference type="DOI" id="10.1038/ncomms4657"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2014-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Genoscope - CEA"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="9" key="3">
        <citation type="submission" date="2021-09" db="UniProtKB">
            <authorList>
                <consortium name="Ensembl"/>
            </authorList>
        </citation>
        <scope>IDENTIFICATION</scope>
    </reference>
    <comment type="function">
        <text evidence="5 6">In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the parvalbumin family.</text>
    </comment>
    <dbReference type="EMBL" id="FR904841">
        <property type="protein sequence ID" value="CDQ72563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000084075.2">
        <property type="protein sequence ID" value="ENSOMYP00000077231.2"/>
        <property type="gene ID" value="ENSOMYG00000035703.2"/>
    </dbReference>
    <dbReference type="GeneTree" id="ENSGT00940000165760"/>
    <dbReference type="OrthoDB" id="1524081at2759"/>
    <dbReference type="Proteomes" id="UP000193380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000694395">
        <property type="component" value="Chromosome 20"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0000314"/>
        <property type="project" value="AgBase"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043679">
        <property type="term" value="C:axon terminus"/>
        <property type="evidence" value="ECO:0000314"/>
        <property type="project" value="AgBase"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030425">
        <property type="term" value="C:dendrite"/>
        <property type="evidence" value="ECO:0000314"/>
        <property type="project" value="AgBase"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016528">
        <property type="term" value="C:sarcoplasm"/>
        <property type="evidence" value="ECO:0000314"/>
        <property type="project" value="AgBase"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0000314"/>
        <property type="project" value="AgBase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008080">
        <property type="entry name" value="Parvalbumin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11653">
        <property type="entry name" value="PTHR11653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0106">Calcium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0514">Muscle protein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="38"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="77"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CDQ72563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Ensembl" id="ENSOMYP00000077231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000193380"/>
        </source>
    </evidence>
    <sequence length="108" mass="11380" checksum="751568573A67BDAD" modified="2014-09-03" version="1">MSFAGLNDADVAAALAACTAADSFNHKAFFAKVGLAGKSNDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSASARALTDAETKAFLADGDKDGDGMIGVDEFAAMIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-09-03" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A060XCT0</accession>
    <name>A0A060XCT0_ONCMY</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Rhodopsin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GSONMT00057700001</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Oncorhynchus mykiss</name>
        <name type="common">Rainbow trout</name>
        <name type="synonym">Salmo gairdneri</name>
        <dbReference type="NCBI Taxonomy" id="8022"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Chordata</taxon>
            <taxon>Craniata</taxon>
            <taxon>Vertebrata</taxon>
            <taxon>Euteleostomi</taxon>
            <taxon>Actinopterygii</taxon>
            <taxon>Neopterygii</taxon>
            <taxon>Teleostei</taxon>
            <taxon>Protacanthopterygii</taxon>
            <taxon>Salmoniformes</taxon>
            <taxon>Salmonidae</taxon>
            <taxon>Salmoninae</taxon>
            <taxon>Oncorhynchus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2014" name="Nat. Commun." volume="5" first="3657" last="3657">
            <title>The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates.</title>
            <authorList>
                <person name="Berthelot C."/>
                <person name="Brunet F."/>
                <person name="Chalopin D."/>
                <person name="Juanchich A."/>
                <person name="Bernard M."/>
                <person name="Noel B."/>
                <person name="Bento P."/>
                <person name="Da Silva C."/>
                <person name="Labadie K."/>
                <person name="Alberti A."/>
                <person name="Aury J.M."/>
                <person name="Louis A."/>
                <person name="Dehais P."/>
                <person name="Bardou P."/>
                <person name="Montfort J."/>
                <person name="Klopp C."/>
                <person name="Cabau C."/>
                <person name="Gaspin C."/>
                <person name="Thorgaard G.H."/>
                <person name="Boussaha M."/>
                <person name="Quillet E."/>
                <person name="Guyomard R."/>
                <person name="Galiana D."/>
                <person name="Bobe J."/>
                <person name="Volff J.N."/>
                <person name="Genet C."/>
                <person name="Wincker P."/>
                <person name="Jaillon O."/>
                <person name="Roest Crollius H."/>
                <person name="Guiguen Y."/>
            </authorList>
            <dbReference type="PubMed" id="24755649"/>
            <dbReference type="DOI" id="10.1038/ncomms4657"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2014-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Genoscope - CEA"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="16" key="3">
        <citation type="submission" date="2021-09" db="UniProtKB">
            <authorList>
                <consortium name="Ensembl"/>
            </authorList>
        </citation>
        <scope>IDENTIFICATION</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="FR904989">
        <property type="protein sequence ID" value="CDQ74665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="8022.A0A060XCT0"/>
    <dbReference type="Ensembl" id="ENSOMYT00000024074.2">
        <property type="protein sequence ID" value="ENSOMYP00000021958.1"/>
        <property type="gene ID" value="ENSOMYG00000010506.2"/>
    </dbReference>
    <dbReference type="GeneTree" id="ENSGT01030000234549"/>
    <dbReference type="Proteomes" id="UP000193380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000694395">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001760">
        <property type="entry name" value="Opsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027430">
        <property type="entry name" value="Retinal_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000732">
        <property type="entry name" value="Rhodopsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019477">
        <property type="entry name" value="Rhodopsin_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10413">
        <property type="entry name" value="Rhodopsin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00238">
        <property type="entry name" value="OPSIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00579">
        <property type="entry name" value="RHODOPSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00238">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0157">Chromophore</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="2 13" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4 13" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13" id="KW-0807">Transducer</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="103"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="204"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="G_PROTEIN_RECEP_F1_2" evidence="14">
        <location>
            <begin position="55"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CDQ74665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Ensembl" id="ENSOMYP00000021958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000193380"/>
        </source>
    </evidence>
    <sequence length="346" mass="37872" checksum="AC5FA841CE8D5152" modified="2014-09-03" version="1">MQNGTEGSNFYIPMSNRTGLVRSPFLYQQYYLAPPWQYYCLAVYTFFLICFGFPINGLTLYVTATNKKLRQPLNFILVNLAAAGMIMVLFGFTITITSAVNGYFIWGPLGCAIEGFMATLGGEVALWSLVVLAVERYIVVCKPMGSFTFTSTHAGAGVAFTWIAAMACAAPPLLGWSRYIPEGMQCSCGPDYYTLAEGFNNESYVIYMFTCHFIIPVCLIAFTYGSLVLTVKAAAASQQDSASTQKAEKEVTRMCILMVCGFMIAWTPYASLAAYIFFNKGIAFSAQSMAIPAFFSKSSALFNPIIYVMMNKQFRGCMLATVGMKAEEDETSVSTSKTEVSSVGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-09-03" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A060XZ25</accession>
    <name>A0A060XZ25_ONCMY</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GLOBIN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GSONMT00052301001</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Oncorhynchus mykiss</name>
        <name type="common">Rainbow trout</name>
        <name type="synonym">Salmo gairdneri</name>
        <dbReference type="NCBI Taxonomy" id="8022"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Chordata</taxon>
            <taxon>Craniata</taxon>
            <taxon>Vertebrata</taxon>
            <taxon>Euteleostomi</taxon>
            <taxon>Actinopterygii</taxon>
            <taxon>Neopterygii</taxon>
            <taxon>Teleostei</taxon>
            <taxon>Protacanthopterygii</taxon>
            <taxon>Salmoniformes</taxon>
            <taxon>Salmonidae</taxon>
            <taxon>Salmoninae</taxon>
            <taxon>Oncorhynchus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2014" name="Nat. Commun." volume="5" first="3657" last="3657">
            <title>The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates.</title>
            <authorList>
                <person name="Berthelot C."/>
                <person name="Brunet F."/>
                <person name="Chalopin D."/>
                <person name="Juanchich A."/>
                <person name="Bernard M."/>
                <person name="Noel B."/>
                <person name="Bento P."/>
                <person name="Da Silva C."/>
                <person name="Labadie K."/>
                <person name="Alberti A."/>
                <person name="Aury J.M."/>
                <person name="Louis A."/>
                <person name="Dehais P."/>
                <person name="Bardou P."/>
                <person name="Montfort J."/>
                <person name="Klopp C."/>
                <person name="Cabau C."/>
                <person name="Gaspin C."/>
                <person name="Thorgaard G.H."/>
                <person name="Boussaha M."/>
                <person name="Quillet E."/>
                <person name="Guyomard R."/>
                <person name="Galiana D."/>
                <person name="Bobe J."/>
                <person name="Volff J.N."/>
                <person name="Genet C."/>
                <person name="Wincker P."/>
                <person name="Jaillon O."/>
                <person name="Roest Crollius H."/>
                <person name="Guiguen Y."/>
            </authorList>
            <dbReference type="PubMed" id="24755649"/>
            <dbReference type="DOI" id="10.1038/ncomms4657"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2014-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Genoscope - CEA"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2021-09" db="UniProtKB">
            <authorList>
                <consortium name="Ensembl"/>
            </authorList>
        </citation>
        <scope>IDENTIFICATION</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the globin family.</text>
    </comment>
    <dbReference type="EMBL" id="FR905966">
        <property type="protein sequence ID" value="CDQ82389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000083190.2">
        <property type="protein sequence ID" value="ENSOMYP00000076426.1"/>
        <property type="gene ID" value="ENSOMYG00000035352.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000106179.2">
        <property type="protein sequence ID" value="ENSOMYP00000097767.2"/>
        <property type="gene ID" value="ENSOMYG00000035352.2"/>
    </dbReference>
    <dbReference type="GeneTree" id="ENSGT00940000157809"/>
    <dbReference type="OrthoDB" id="1370439at2759"/>
    <dbReference type="Proteomes" id="UP000193380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000694395">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005833">
        <property type="term" value="C:hemoglobin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08925">
        <property type="entry name" value="Hb-beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002337">
        <property type="entry name" value="Hemoglobin_b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00814">
        <property type="entry name" value="BETAHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GLOBIN" evidence="9">
        <location>
            <begin position="5"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="binding site" description="distal binding residue" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="proximal binding residue" evidence="7">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CDQ82389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Ensembl" id="ENSOMYP00000076426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000193380"/>
        </source>
    </evidence>
    <sequence length="147" mass="15946" checksum="3CE760644FC52C44" modified="2014-09-03" version="1">MADWTDAEKSTISAVWGKVDINEVGPLALGRVLIVYPWTQRYFGSFGDVSTAAAIMGNPKVAAHGKVVCGALDKAVKNMGNILATYKSLSETHANKLFVDPENFRVLADVLTIVIAAKFGAAFTPEIQATWQKFMKVVVAAMSSRYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-09-03" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A060YJ58</accession>
    <accession>A0A8C7P931</accession>
    <name>A0A060YJ58_ONCMY</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 5A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">eif5a</name>
        <name evidence="4" type="ORF">GSONMT00035586001</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Oncorhynchus mykiss</name>
        <name type="common">Rainbow trout</name>
        <name type="synonym">Salmo gairdneri</name>
        <dbReference type="NCBI Taxonomy" id="8022"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Chordata</taxon>
            <taxon>Craniata</taxon>
            <taxon>Vertebrata</taxon>
            <taxon>Euteleostomi</taxon>
            <taxon>Actinopterygii</taxon>
            <taxon>Neopterygii</taxon>
            <taxon>Teleostei</taxon>
            <taxon>Protacanthopterygii</taxon>
            <taxon>Salmoniformes</taxon>
            <taxon>Salmonidae</taxon>
            <taxon>Salmoninae</taxon>
            <taxon>Oncorhynchus</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2014" name="Nat. Commun." volume="5" first="3657" last="3657">
            <title>The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates.</title>
            <authorList>
                <person name="Berthelot C."/>
                <person name="Brunet F."/>
                <person name="Chalopin D."/>
                <person name="Juanchich A."/>
                <person name="Bernard M."/>
                <person name="Noel B."/>
                <person name="Bento P."/>
                <person name="Da Silva C."/>
                <person name="Labadie K."/>
                <person name="Alberti A."/>
                <person name="Aury J.M."/>
                <person name="Louis A."/>
                <person name="Dehais P."/>
                <person name="Bardou P."/>
                <person name="Montfort J."/>
                <person name="Klopp C."/>
                <person name="Cabau C."/>
                <person name="Gaspin C."/>
                <person name="Thorgaard G.H."/>
                <person name="Boussaha M."/>
                <person name="Quillet E."/>
                <person name="Guyomard R."/>
                <person name="Galiana D."/>
                <person name="Bobe J."/>
                <person name="Volff J.N."/>
                <person name="Genet C."/>
                <person name="Wincker P."/>
                <person name="Jaillon O."/>
                <person name="Roest Crollius H."/>
                <person name="Guiguen Y."/>
            </authorList>
            <dbReference type="PubMed" id="24755649"/>
            <dbReference type="DOI" id="10.1038/ncomms4657"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2014-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Genoscope - CEA"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="5" key="3">
        <citation type="submission" date="2021-09" db="UniProtKB">
            <authorList>
                <consortium name="Ensembl"/>
            </authorList>
        </citation>
        <scope>IDENTIFICATION</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="FR909558">
        <property type="protein sequence ID" value="CDQ89489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="8022.A0A060YJ58"/>
    <dbReference type="Ensembl" id="ENSOMYT00000019901.2">
        <property type="protein sequence ID" value="ENSOMYP00000018076.2"/>
        <property type="gene ID" value="ENSOMYG00000008821.2"/>
    </dbReference>
    <dbReference type="GeneTree" id="ENSGT00940000154509"/>
    <dbReference type="OrthoDB" id="1594080at2759"/>
    <dbReference type="Proteomes" id="UP000193380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000694395">
        <property type="component" value="Chromosome 15"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002671">
        <property type="entry name" value="Ribosomal_L22e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038526">
        <property type="entry name" value="Ribosomal_L22e_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028370">
        <property type="entry name" value="RPL22L1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064">
        <property type="entry name" value="PTHR10064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064:SF1">
        <property type="entry name" value="PTHR10064:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01776">
        <property type="entry name" value="Ribosomal_L22e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CDQ89489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Ensembl" id="ENSOMYP00000018076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000193380"/>
        </source>
    </evidence>
    <sequence length="129" mass="15242" checksum="6A280EBD912F6249" modified="2014-09-03" version="1">MAPLKQKKQTVVKRTKRGVSWKFTLDLTHPVEDGILDSANFETFLKERVKVNGKTGNLANVIEIARLKNKINVTSQKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQEEEESDNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-09-03" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A060YUB7</accession>
    <name>A0A060YUB7_ONCMY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">40S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GSONMT00020818001</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Oncorhynchus mykiss</name>
        <name type="common">Rainbow trout</name>
        <name type="synonym">Salmo gairdneri</name>
        <dbReference type="NCBI Taxonomy" id="8022"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Chordata</taxon>
            <taxon>Craniata</taxon>
            <taxon>Vertebrata</taxon>
            <taxon>Euteleostomi</taxon>
            <taxon>Actinopterygii</taxon>
            <taxon>Neopterygii</taxon>
            <taxon>Teleostei</taxon>
            <taxon>Protacanthopterygii</taxon>
            <taxon>Salmoniformes</taxon>
            <taxon>Salmonidae</taxon>
            <taxon>Salmoninae</taxon>
            <taxon>Oncorhynchus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2014" name="Nat. Commun." volume="5" first="3657" last="3657">
            <title>The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates.</title>
            <authorList>
                <person name="Berthelot C."/>
                <person name="Brunet F."/>
                <person name="Chalopin D."/>
                <person name="Juanchich A."/>
                <person name="Bernard M."/>
                <person name="Noel B."/>
                <person name="Bento P."/>
                <person name="Da Silva C."/>
                <person name="Labadie K."/>
                <person name="Alberti A."/>
                <person name="Aury J.M."/>
                <person name="Louis A."/>
                <person name="Dehais P."/>
                <person name="Bardou P."/>
                <person name="Montfort J."/>
                <person name="Klopp C."/>
                <person name="Cabau C."/>
                <person name="Gaspin C."/>
                <person name="Thorgaard G.H."/>
                <person name="Boussaha M."/>
                <person name="Quillet E."/>
                <person name="Guyomard R."/>
                <person name="Galiana D."/>
                <person name="Bobe J."/>
                <person name="Volff J.N."/>
                <person name="Genet C."/>
                <person name="Wincker P."/>
                <person name="Jaillon O."/>
                <person name="Roest Crollius H."/>
                <person name="Guiguen Y."/>
            </authorList>
            <dbReference type="PubMed" id="24755649"/>
            <dbReference type="DOI" id="10.1038/ncomms4657"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2014-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Genoscope - CEA"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="8" key="3">
        <citation type="submission" date="2021-09" db="UniProtKB">
            <authorList>
                <consortium name="Ensembl"/>
            </authorList>
        </citation>
        <scope>IDENTIFICATION</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the eukaryotic ribosomal protein eS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="FR914393">
        <property type="protein sequence ID" value="CDQ93059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="8022.A0A060YUB7"/>
    <dbReference type="Ensembl" id="ENSOMYT00000021357.2">
        <property type="protein sequence ID" value="ENSOMYP00000019433.1"/>
        <property type="gene ID" value="ENSOMYG00000009406.2"/>
    </dbReference>
    <dbReference type="GeneTree" id="ENSGT00390000012433"/>
    <dbReference type="Proteomes" id="UP000193380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000694395">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.168.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042563">
        <property type="entry name" value="Ribosomal_protein_S8e_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001047">
        <property type="entry name" value="Ribosomal_S8e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_S8e/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018283">
        <property type="entry name" value="Ribosomal_S8e_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10394">
        <property type="entry name" value="PTHR10394"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00307">
        <property type="entry name" value="eS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01193">
        <property type="entry name" value="RIBOSOMAL_S8E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035036747" description="40S ribosomal protein S8" evidence="6">
        <location>
            <begin position="24"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CDQ93059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Ensembl" id="ENSOMYP00000019433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000193380"/>
        </source>
    </evidence>
    <sequence length="234" mass="26923" checksum="722C7895B02C3B92" modified="2014-09-03" version="1">MASFGFSVFLFVAKFASFSLVSCFCGPGISRDNWHKRRKTGGKRKPYHKKRKYELGRPPANTKIGPRRIHTVRTRGGNKKYRALRVDVGNFSWGSECCTRKTRLIDVVYNASNNELVRTKTLVKNCIVLVDSLPYRQWYEAHFATPLGRKKGAKLTPEEEEVINKKRSKKIQKKFDERKKNCKISPLLEEQFMQGKLLACIASKPGQCGRVDGYILEGKELEFYLRKIKAKKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2014-09-03" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A060Z878</accession>
    <name>A0A060Z878_ONCMY</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GSONMT00044173001</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Oncorhynchus mykiss</name>
        <name type="common">Rainbow trout</name>
        <name type="synonym">Salmo gairdneri</name>
        <dbReference type="NCBI Taxonomy" id="8022"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Chordata</taxon>
            <taxon>Craniata</taxon>
            <taxon>Vertebrata</taxon>
            <taxon>Euteleostomi</taxon>
            <taxon>Actinopterygii</taxon>
            <taxon>Neopterygii</taxon>
            <taxon>Teleostei</taxon>
            <taxon>Protacanthopterygii</taxon>
            <taxon>Salmoniformes</taxon>
            <taxon>Salmonidae</taxon>
            <taxon>Salmoninae</taxon>
            <taxon>Oncorhynchus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2014" name="Nat. Commun." volume="5" first="3657" last="3657">
            <title>The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates.</title>
            <authorList>
                <person name="Berthelot C."/>
                <person name="Brunet F."/>
                <person name="Chalopin D."/>
                <person name="Juanchich A."/>
                <person name="Bernard M."/>
                <person name="Noel B."/>
                <person name="Bento P."/>
                <person name="Da Silva C."/>
                <person name="Labadie K."/>
                <person name="Alberti A."/>
                <person name="Aury J.M."/>
                <person name="Louis A."/>
                <person name="Dehais P."/>
                <person name="Bardou P."/>
                <person name="Montfort J."/>
                <person name="Klopp C."/>
                <person name="Cabau C."/>
                <person name="Gaspin C."/>
                <person name="Thorgaard G.H."/>
                <person name="Boussaha M."/>
                <person name="Quillet E."/>
                <person name="Guyomard R."/>
                <person name="Galiana D."/>
                <person name="Bobe J."/>
                <person name="Volff J.N."/>
                <person name="Genet C."/>
                <person name="Wincker P."/>
                <person name="Jaillon O."/>
                <person name="Roest Crollius H."/>
                <person name="Guiguen Y."/>
            </authorList>
            <dbReference type="PubMed" id="24755649"/>
            <dbReference type="DOI" id="10.1038/ncomms4657"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2014-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Genoscope - CEA"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="4" key="3">
        <citation type="submission" date="2022-04" db="UniProtKB">
            <authorList>
                <consortium name="Ensembl"/>
            </authorList>
        </citation>
        <scope>IDENTIFICATION</scope>
    </reference>
    <dbReference type="EMBL" id="FR931268">
        <property type="protein sequence ID" value="CDQ97510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000135472.1">
        <property type="protein sequence ID" value="ENSOMYP00000122754.1"/>
        <property type="gene ID" value="ENSOMYG00000053467.1"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1447698at2759"/>
    <dbReference type="Proteomes" id="UP000193380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000694395">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="SSF49562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5001596916" description="C2 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CDQ97510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Ensembl" id="ENSOMYP00000122754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000193380"/>
        </source>
    </evidence>
    <sequence length="136" mass="15232" checksum="48C3EFC641AE109B" modified="2014-09-03" version="1">MASLSLSLGLLVLCTLALVHCDLDDVQVRVWGLSASNLKVDLLSQPDPYVKVWYGPAFGGMSSILKNQANPTWPDEFNFLDMIHNSVLKLEVWDNNVGPDHRLGTCTTTIRPGTHTETCHLKKGTVYYTYSYDYSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-05-26" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>C1BFD8</accession>
    <name>C1BFD8_ONCMY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Hemoglobin subunit beta-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HBB1</name>
        <name evidence="11" type="ORF">GSONMT00008811001</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Oncorhynchus mykiss</name>
        <name type="common">Rainbow trout</name>
        <name type="synonym">Salmo gairdneri</name>
        <dbReference type="NCBI Taxonomy" id="8022"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Chordata</taxon>
            <taxon>Craniata</taxon>
            <taxon>Vertebrata</taxon>
            <taxon>Euteleostomi</taxon>
            <taxon>Actinopterygii</taxon>
            <taxon>Neopterygii</taxon>
            <taxon>Teleostei</taxon>
            <taxon>Protacanthopterygii</taxon>
            <taxon>Salmoniformes</taxon>
            <taxon>Salmonidae</taxon>
            <taxon>Salmoninae</taxon>
            <taxon>Oncorhynchus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2009-03" db="EMBL/GenBank/DDBJ databases">
            <title>Oncorhynchus mykiss ESTs and full-length cDNAs from Red Blood Cells.</title>
            <authorList>
                <consortium name="cGRASP (B.F. Koop &amp; W.S. Davidson)"/>
                <person name="Yasuike M."/>
                <person name="von Schalburg K."/>
                <person name="Cooper G."/>
                <person name="Leong J."/>
                <person name="Davidson W.S."/>
                <person name="Koop B.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <tissue evidence="10">Red blood cell</tissue>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2014" name="Nat. Commun." volume="5" first="3657" last="3657">
            <title>The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates.</title>
            <authorList>
                <person name="Berthelot C."/>
                <person name="Brunet F."/>
                <person name="Chalopin D."/>
                <person name="Juanchich A."/>
                <person name="Bernard M."/>
                <person name="Noel B."/>
                <person name="Bento P."/>
                <person name="Da Silva C."/>
                <person name="Labadie K."/>
                <person name="Alberti A."/>
                <person name="Aury J.M."/>
                <person name="Louis A."/>
                <person name="Dehais P."/>
                <person name="Bardou P."/>
                <person name="Montfort J."/>
                <person name="Klopp C."/>
                <person name="Cabau C."/>
                <person name="Gaspin C."/>
                <person name="Thorgaard G.H."/>
                <person name="Boussaha M."/>
                <person name="Quillet E."/>
                <person name="Guyomard R."/>
                <person name="Galiana D."/>
                <person name="Bobe J."/>
                <person name="Volff J.N."/>
                <person name="Genet C."/>
                <person name="Wincker P."/>
                <person name="Jaillon O."/>
                <person name="Roest Crollius H."/>
                <person name="Guiguen Y."/>
            </authorList>
            <dbReference type="PubMed" id="24755649"/>
            <dbReference type="DOI" id="10.1038/ncomms4657"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2014-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Genoscope - CEA"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="12" key="4">
        <citation type="submission" date="2021-09" db="UniProtKB">
            <authorList>
                <consortium name="Ensembl"/>
            </authorList>
        </citation>
        <scope>IDENTIFICATION</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the globin family.</text>
    </comment>
    <dbReference type="EMBL" id="BT073317">
        <property type="protein sequence ID" value="ACO07741.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FR912552">
        <property type="protein sequence ID" value="CDQ91979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000083200.2">
        <property type="protein sequence ID" value="ENSOMYP00000076434.1"/>
        <property type="gene ID" value="ENSOMYG00000035352.2"/>
    </dbReference>
    <dbReference type="GeneTree" id="ENSGT00940000157809"/>
    <dbReference type="OrthoDB" id="1370439at2759"/>
    <dbReference type="Proteomes" id="UP000193380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000694395">
        <property type="component" value="Chromosome 13"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005833">
        <property type="term" value="C:hemoglobin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08925">
        <property type="entry name" value="Hb-beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002337">
        <property type="entry name" value="Hemoglobin_b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00814">
        <property type="entry name" value="BETAHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="3 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GLOBIN" evidence="9">
        <location>
            <begin position="5"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="binding site" description="distal binding residue" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="proximal binding residue" evidence="7">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ACO07741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CDQ91979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Ensembl" id="ENSOMYP00000076434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000193380"/>
        </source>
    </evidence>
    <sequence length="147" mass="15929" checksum="2085C523B0A13AF1" modified="2009-05-26" version="1">MADWTDAEKSTISAVWGKVDINEVGPLALGRVLIVYPWTQRYFGSFGDVSTAAAIMGNPKVAAHGRVVCGALDKAVKNMGNILATYKSLSETHANKLFVDPDNFRVLADVLTIVIAAKFGAAFTPEIQATWQKFMKVVVAAMGSRYF</sequence>
</entry>
<entry dataset="TrEMBL" created="1999-05-01" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>Q9YGF5</accession>
    <accession>A0A8C7REQ8</accession>
    <accession>A0A8C7RG10</accession>
    <accession>A0A8C7UHZ0</accession>
    <accession>A0A8C7ULB7</accession>
    <accession>A0A8C7UMG6</accession>
    <accession>A0A8C7UQU0</accession>
    <accession>A0A8C7UUX0</accession>
    <name>Q9YGF5_ONCMY</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Embryonic beta-type globin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GSONMT00009490001</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Oncorhynchus mykiss</name>
        <name type="common">Rainbow trout</name>
        <name type="synonym">Salmo gairdneri</name>
        <dbReference type="NCBI Taxonomy" id="8022"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Chordata</taxon>
            <taxon>Craniata</taxon>
            <taxon>Vertebrata</taxon>
            <taxon>Euteleostomi</taxon>
            <taxon>Actinopterygii</taxon>
            <taxon>Neopterygii</taxon>
            <taxon>Teleostei</taxon>
            <taxon>Protacanthopterygii</taxon>
            <taxon>Salmoniformes</taxon>
            <taxon>Salmonidae</taxon>
            <taxon>Salmoninae</taxon>
            <taxon>Oncorhynchus</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="1999" name="Dev. Growth Differ." volume="41" first="589" last="599">
            <title>Characterization and expression of embryonic globin in the rainbow trout, Oncorhynchus mykiss: intra-embryonic initiation of erythropoiesis.</title>
            <authorList>
                <person name="Maruyama K."/>
                <person name="Yasumasu S."/>
                <person name="Iuchi I."/>
            </authorList>
            <dbReference type="PubMed" id="10545031"/>
            <dbReference type="DOI" id="10.1046/j.1440-169x.1999.00460.x"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="11" key="2">
        <citation type="journal article" date="2014" name="Nat. Commun." volume="5" first="3657" last="3657">
            <title>The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates.</title>
            <authorList>
                <person name="Berthelot C."/>
                <person name="Brunet F."/>
                <person name="Chalopin D."/>
                <person name="Juanchich A."/>
                <person name="Bernard M."/>
                <person name="Noel B."/>
                <person name="Bento P."/>
                <person name="Da Silva C."/>
                <person name="Labadie K."/>
                <person name="Alberti A."/>
                <person name="Aury J.M."/>
                <person name="Louis A."/>
                <person name="Dehais P."/>
                <person name="Bardou P."/>
                <person name="Montfort J."/>
                <person name="Klopp C."/>
                <person name="Cabau C."/>
                <person name="Gaspin C."/>
                <person name="Thorgaard G.H."/>
                <person name="Boussaha M."/>
                <person name="Quillet E."/>
                <person name="Guyomard R."/>
                <person name="Galiana D."/>
                <person name="Bobe J."/>
                <person name="Volff J.N."/>
                <person name="Genet C."/>
                <person name="Wincker P."/>
                <person name="Jaillon O."/>
                <person name="Roest Crollius H."/>
                <person name="Guiguen Y."/>
            </authorList>
            <dbReference type="PubMed" id="24755649"/>
            <dbReference type="DOI" id="10.1038/ncomms4657"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <reference evidence="11" key="3">
        <citation type="submission" date="2014-03" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Genoscope - CEA"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="12" key="4">
        <citation type="submission" date="2022-04" db="UniProtKB">
            <authorList>
                <consortium name="Ensembl"/>
            </authorList>
        </citation>
        <scope>IDENTIFICATION</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the globin family.</text>
    </comment>
    <dbReference type="EMBL" id="AB015450">
        <property type="protein sequence ID" value="BAA34950.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FR905513">
        <property type="protein sequence ID" value="CDQ79873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_001117659.1">
        <property type="nucleotide sequence ID" value="NM_001124187.1"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000054963.2">
        <property type="protein sequence ID" value="ENSOMYP00000050572.2"/>
        <property type="gene ID" value="ENSOMYG00000044375.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000054970.2">
        <property type="protein sequence ID" value="ENSOMYP00000050579.2"/>
        <property type="gene ID" value="ENSOMYG00000044375.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000091747.2">
        <property type="protein sequence ID" value="ENSOMYP00000084224.1"/>
        <property type="gene ID" value="ENSOMYG00000044375.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000106098.2">
        <property type="protein sequence ID" value="ENSOMYP00000097694.2"/>
        <property type="gene ID" value="ENSOMYG00000044399.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000106102.2">
        <property type="protein sequence ID" value="ENSOMYP00000097698.2"/>
        <property type="gene ID" value="ENSOMYG00000044399.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000106105.2">
        <property type="protein sequence ID" value="ENSOMYP00000097699.2"/>
        <property type="gene ID" value="ENSOMYG00000044399.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000106109.2">
        <property type="protein sequence ID" value="ENSOMYP00000097703.1"/>
        <property type="gene ID" value="ENSOMYG00000044399.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000106115.2">
        <property type="protein sequence ID" value="ENSOMYP00000097709.2"/>
        <property type="gene ID" value="ENSOMYG00000044399.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000106122.2">
        <property type="protein sequence ID" value="ENSOMYP00000097715.2"/>
        <property type="gene ID" value="ENSOMYG00000044399.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000106139.2">
        <property type="protein sequence ID" value="ENSOMYP00000097731.2"/>
        <property type="gene ID" value="ENSOMYG00000044375.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000106193.2">
        <property type="protein sequence ID" value="ENSOMYP00000097781.2"/>
        <property type="gene ID" value="ENSOMYG00000044375.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000119907.1">
        <property type="protein sequence ID" value="ENSOMYP00000139379.1"/>
        <property type="gene ID" value="ENSOMYG00000044399.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000131092.1">
        <property type="protein sequence ID" value="ENSOMYP00000118715.1"/>
        <property type="gene ID" value="ENSOMYG00000044399.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000143624.1">
        <property type="protein sequence ID" value="ENSOMYP00000128442.1"/>
        <property type="gene ID" value="ENSOMYG00000044399.2"/>
    </dbReference>
    <dbReference type="Ensembl" id="ENSOMYT00000159269.1">
        <property type="protein sequence ID" value="ENSOMYP00000106973.1"/>
        <property type="gene ID" value="ENSOMYG00000044399.2"/>
    </dbReference>
    <dbReference type="GeneID" id="100135791"/>
    <dbReference type="KEGG" id="omy:100135791"/>
    <dbReference type="GeneTree" id="ENSGT00940000157809"/>
    <dbReference type="OrthoDB" id="1370439at2759"/>
    <dbReference type="Proteomes" id="UP000193380">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000694395">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005833">
        <property type="term" value="C:hemoglobin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08925">
        <property type="entry name" value="Hb-beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002337">
        <property type="entry name" value="Hemoglobin_b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00814">
        <property type="entry name" value="BETAHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="3 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GLOBIN" evidence="9">
        <location>
            <begin position="5"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="binding site" description="distal binding residue" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="proximal binding residue" evidence="7">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAA34950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CDQ79873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Ensembl" id="ENSOMYP00000106973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000193380"/>
        </source>
    </evidence>
    <sequence length="147" mass="16396" checksum="79E874B4EFAA13EA" modified="1999-05-01" version="1">MVQWTDFERATIQSVFEKMDYDDVGPAALSRCLVVYPWTQRYFGNFGNLYNAAAIQGNPMVAAHGKTVLRGLDRAVKNMDDIKATYAELSVLHSEKLRVDPDNFRLLADCLTIVVAARMGADFTADVQGAFQKFLAVVVSSLGRQYH</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>